LOCUS NC_009566 1813033 bp DNA circular BCT 29-DEC-2012
DEFINITION Haemophilus influenzae PittEE chromosome, complete genome.
ACCESSION NC_009566
VERSION NC_009566.1 GI:148825133
DBLINK Project: 58591
BioProject: PRJNA58591
KEYWORDS .
SOURCE Haemophilus influenzae PittEE
ORGANISM Haemophilus influenzae PittEE
Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
Pasteurellaceae; Haemophilus.
REFERENCE 1 (bases 1 to 1813033)
AUTHORS Hogg,J.S., Hu,F.Z., Janto,B., Boissy,R., Hayes,J., Keefe,R.,
Post,J.C. and Ehrlich,G.D.
TITLE Characterization and modeling of the Haemophilus influenzae core
and supragenomes based on the complete genomic sequences of Rd and
12 clinical nontypeable strains
JOURNAL Genome Biol. 8 (6), R103 (2007)
PUBMED 17550610
REFERENCE 2 (bases 1 to 1813033)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (05-SEP-2007) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 1813033)
AUTHORS Ehrlich,G.D.
TITLE Direct Submission
JOURNAL Submitted (10-APR-2007) Center for Genomic Sciences,
Allegheny-Singer Research Institute, 320 E. North Ave. 11th Floor,
Pittsburgh, PA 15212-4772, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from CP000671.
Annotation was added by the NCBI Prokaryotic Genomes Automatic
Annotation Pipeline Group. Information about the Pipeline can be
found here:
http://www.ncbi.nlm.nih.gov/genomes/static/Pipeline.html. Please be
aware that the annotation is done automatically with little or no
manual curation.
Annotation updated by the NCBI Prokaryotic Genomes Automatic
Annotation Pipeline Group on September 9, 2007.
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..1813033
/organism="Haemophilus influenzae PittEE"
/mol_type="genomic DNA"
/strain="PittEE"
/db_xref="taxon:374930"
gene 1450..4413
/locus_tag="CGSHiEE_00010"
/db_xref="GeneID:5226334"
CDS 1450..4413
/locus_tag="CGSHiEE_00010"
/note="COG1629 Outer membrane receptor proteins, mostly Fe
transport"
/codon_start=1
/transl_table=11
/product="hemoglobin-haptoglobin binding protein B"
/protein_id="YP_001289887.1"
/db_xref="GI:148825134"
/db_xref="GeneID:5226334"
/translation="MTNFRLNALAYSVMLGLTASVAYAEPTNQPTNQPTNQNSNLSEQ
LEQINVSGSTENSDSKTPPKIAETVKTAKTLEREQANNIKDIVKYETGVTVVEAGRFG
QSGFAIRGVDENRVAINIDGLRQAETLSSQGFKELFEGYGNFNNTRNGAEIETLKEVN
ITKGANSIKSGSGSLGGSVIYKTKDARDYLLNKDYYVSYKKGYATENNQSFNTLTLAG
RYKKFDALVVTTRRNGHELENYDYKNANSLTQGKKREKADPYKIEQDSTLLKFSFNPT
ENHRFTLAADLYEHRSRGQDLSYTLKYQKTNPDLPEVESRHTNDKTKRRNISFSYENF
SQTPFWDTLKITFSKQKIKTRARTDEYCDAGVRHCQGTENPTGLKLTDGKITRRDGTP
LKFKEKTTNGTEKTYDFDKFIDTNDQEIEGKLTRKRASETWYDCSIFNCKDGTKINVF
EGKRHYGHEGKWKEVELEKKEINGKTFARIKDKDNNNYNYGKIQSIFPSSPGYLERLW
QERDLDTNTQQLNLDLTKDFKTWRVEHNLQYGSSYNTTMKRMVNRAGNDATDVQWWAE
RTLGTKTNLFSPTQQEIPRTCEDSLDPNLCPRVDPEFSYLLPIKTKEKSVYLFDNVVI
TDYLSFDLGYRYDNIHYQPKYKHGVTPKLPDDIVKGLFIPLNGKNNNDEVIKKNVQEN
IDYIAKQNKKYKAHSYSFASTIDPTSFLRLQLKYSKGFRAPTSDEMYFTFKHPDFTIL
PNTNLKPEIAKTKEIAFTLHHDDWGFISTSLFKTNYKNFIDLVYKGTQSFKLVSGGDT
LPFSLYQNINRDSAVVKGIEINSKVFLGKMAKFMDGFNLSYKYTYQKGRINGNIPMNA
IQPKTMVYGLGYDHPSQKFGFNFYTTHVATKNPEDTYDIYAEDKRQTDTSIKWRSKSY
TILDLIGYVQPIKNLTIRAGVYNLTNRKYITWDSARSIRSFGTSNVIEQTTGLGINRF
YAPGRNYKMSVQFEF"
misc_feature 1651..1950
/locus_tag="CGSHiEE_00010"
/note="TonB-dependent Receptor Plug Domain; Region: Plug;
pfam07715"
/db_xref="CDD:203737"
misc_feature <2941..4410
/locus_tag="CGSHiEE_00010"
/note="TonB dependent/Ligand-Gated channels are created by
a monomeric 22 strand (22,24) anti-parallel beta-barrel.
Ligands apparently bind to the large extracellular loops.
The N-terminal 150-200 residues form a plug from the
periplasmic end of barrel; Region: ligand_gated_channel;
cd01347"
/db_xref="CDD:73259"
misc_feature order(3085..3087,3166..3168)
/locus_tag="CGSHiEE_00010"
/note="ligand-binding site [chemical binding]; other site"
/db_xref="CDD:73259"
misc_feature 4873..5578
/note="potential frameshift: common BLAST hit:
gi|68249200|ref|YP_248312.1| peptidase E [Haemophilus
influenzae 86-028NP]"
misc_feature 5596..6892
/note="potential frameshift: common BLAST hit:
gi|68249201|ref|YP_248313.1| predicted C4-dicarboxylate
transporter [Haemophilus influenzae]"
gene 6964..8235
/locus_tag="CGSHiEE_00035"
/db_xref="GeneID:5225155"
CDS 6964..8235
/locus_tag="CGSHiEE_00035"
/EC_number="3.4.13.21"
/note="COG1473 Metal-dependent
amidase/aminoacylase/carboxypeptidase"
/codon_start=1
/transl_table=11
/product="peptidase E"
/protein_id="YP_001289888.1"
/db_xref="GI:148825135"
/db_xref="GeneID:5225155"
/translation="MNLDLNQLVKWRREFHRFPEIGWSEFWTTSRIADYLEDLDCFEI
FLGKQIINPDFVRGRKQAVVDKGLANAKAYGANEKWLEKMEGYTGCVALFDSGKPGKT
IALRFDIDCVNVTETRSPEHIPNKEGFASINDGFMHACGHDSHITIGLGVALWIAQNK
DKLTGKVKIVFQPAEEGVRGAAAIAQSGIIDDADYFASSHISFCANTGTVIANPRNFL
STTKIDIRYKGKPAHAGAAPHLGRNALLAAAHTVTQLHGIARHGEGMTRINVGVLKAG
EGRNVIPSSAELQLEVRGENKAINEYMTEQVMQIAKGISISFDVAYETEIVGEAVDMN
NDVELIKLIEEISLEQPQINNVNSDYAFNASEDATILGRRVQEHGGKAIYFILGADRT
AGHHEAEFDFDENQLLTGVNIYTSLVQKLLS"
misc_feature 6964..8229
/locus_tag="CGSHiEE_00035"
/note="Metal-dependent
amidase/aminoacylase/carboxypeptidase [General function
prediction only]; Region: AbgB; COG1473"
/db_xref="CDD:31662"
misc_feature 6979..8217
/locus_tag="CGSHiEE_00035"
/note="M20 Peptidases Aminoacyclase-1
indole-3-acetic-L-aspartic acid hydrolase from bacteria
and archaea; Region: M20_Acy1_IAAspH_bact; cd05665"
/db_xref="CDD:193541"
misc_feature order(7381..7383,7387..7389,7489..7491,7561..7563,
8149..8151)
/locus_tag="CGSHiEE_00035"
/note="putative metal binding site [ion binding]; other
site"
/db_xref="CDD:193541"
misc_feature order(7627..7635,7696..7701,7711..7713,7720..7722,
7729..7731,7762..7764,7768..7812,7828..7836,7840..7842,
7942..7944,8047..8049)
/locus_tag="CGSHiEE_00035"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:193541"
gene 8329..10302
/gene="cpdB"
/locus_tag="CGSHiEE_00040"
/db_xref="GeneID:5225149"
CDS 8329..10302
/gene="cpdB"
/locus_tag="CGSHiEE_00040"
/EC_number="3.1.4.16"
/EC_number="3.1.3.6"
/note="periplasmic enzyme; functions during ribonucleic
acid degradation; 2',3'-cyclic nucleotides are first
converted to 3'-nucleotide and then cleaved to yield a
ribonucleotide and a phosphate"
/codon_start=1
/transl_table=11
/product="bifunctional 2',3'-cyclic nucleotide
2'-phosphodiesterase/3'-nucleotidase periplasmic protein"
/protein_id="YP_001289889.1"
/db_xref="GI:148825136"
/db_xref="GeneID:5225149"
/translation="MMNRRHFIQIGATSILALSANRFAMAKGKSDVDLRIVATTDVHS
FLTDFDYYKDAPTDKFGFTRAASLIRQARAEVKNSVLVDNGDLIQGNPIADYQAAQGY
KEGKSNPAVDCLNAMNYEVGTLGNHEFNYGLNYLADAIKQAKFPIVNANVVKAGTEEP
YFTPYVIQEKSVVDNNGKTHKLKIGYIGFVPPQIMVWDKANLQGKVETRDIVKTAQKY
VPEMKKKGADIVVALAHTGPSDEPYQEGAENSAFYLADVPHIDAVIFGHSHRLFPNKE
FAKSPNADIVNGTVKGVPESMAGYWANNISVVDLGLTEHKGKWIVTSGKAVLRPIYDV
ETKKALAKNDPEITALLKPVHEATRKYVSQPIGKATDNMYSYLALIQDDPTIQIVNQA
QKAYVEKVAPSVAAMAGLPILSAGAPFKAGGRKNDPTGYTEVNKGELTFRNAADLYLY
PNTLVVVKATGEQLKEWLECSAGMFKQIDPTSDKPQSLIDWEGFRTYNFDVIDGVNYE
YDLTKPARYDGECKLINPESHRVVNLTYQGKPVDPKAEFLIATNNYRAYGNKFPGTGD
QHIVYASPDESRQILADYIKATSEKEGSVNPNADKNWRFVPITGNDKLDVRFETSPSE
QAAKFIAEKAQYPMKQVGTDEIGFAVYQIDLSK"
misc_feature 8329..10299
/gene="cpdB"
/locus_tag="CGSHiEE_00040"
/note="bifunctional 2',3'-cyclic nucleotide
2'-phosphodiesterase/3'-nucleotidase periplasmic precursor
protein; Reviewed; Region: cpdB; PRK09420"
/db_xref="CDD:181840"
misc_feature 8428..9321
/gene="cpdB"
/locus_tag="CGSHiEE_00040"
/note="Escherichia coli CpdB and related proteins,
N-terminal metallophosphatase domain; Region: MPP_CpdB_N;
cd07410"
/db_xref="CDD:163653"
misc_feature order(8449..8451,8455..8457,8584..8586,8704..8709,
9031..9033,9127..9129,9133..9135)
/gene="cpdB"
/locus_tag="CGSHiEE_00040"
/note="active site"
/db_xref="CDD:163653"
misc_feature order(8449..8451,8455..8457,8584..8586,8704..8706,
9031..9033,9127..9129,9133..9135)
/gene="cpdB"
/locus_tag="CGSHiEE_00040"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:163653"
misc_feature 9466..10005
/gene="cpdB"
/locus_tag="CGSHiEE_00040"
/note="5'-nucleotidase, C-terminal domain; Region:
5_nucleotid_C; pfam02872"
/db_xref="CDD:202440"
gene complement(10568..11047)
/gene="cpdB"
/locus_tag="CGSHiEE_00045"
/db_xref="GeneID:5225200"
CDS complement(10568..11047)
/gene="cpdB"
/locus_tag="CGSHiEE_00045"
/EC_number="3.1.4.16"
/note="COG0500 SAM-dependent methyltransferases"
/codon_start=1
/transl_table=11
/product="bifunctional 2',3'-cyclic nucleotide
2'-phosphodiesterase/3'-nucleotidase periplasmic protein"
/protein_id="YP_001289890.1"
/db_xref="GI:148825137"
/db_xref="GeneID:5225200"
/translation="MTNELTFNSDWFTHNVPALEAIMADLKPSKILEIGSFEGRSTVF
FLENMLNIHDKVEIHCIDSWLGGREHIQSGWDMDSVEHQFEENIRTFLHSFNEKKECK
VVKRKGYSHAKMIELLTQGYENYFDFIYVDGSHEATDVLFDALLAHRLVRGGGDNSL"
misc_feature complement(10583..10954)
/gene="cpdB"
/locus_tag="CGSHiEE_00045"
/note="Methyltransferase domain; Region: Methyltransf_24;
pfam13578"
/db_xref="CDD:205756"
gene 11499..13388
/locus_tag="CGSHiEE_00050"
/gene_synonym="gidA"
/db_xref="GeneID:5225201"
CDS 11499..13388
/locus_tag="CGSHiEE_00050"
/gene_synonym="gidA"
/note="GidA; glucose-inhibited cell division protein A;
involved in the 5-carboxymethylaminomethyl modification
(mnm(5)s(2)U) of the wobble uridine base in some tRNAs"
/codon_start=1
/transl_table=11
/product="tRNA uridine 5-carboxymethylaminomethyl
modification enzyme GidA"
/protein_id="YP_001289891.1"
/db_xref="GI:148825138"
/db_xref="GeneID:5225201"
/translation="MFYTETYDVIVIGGGHAGTEAALAPARMGFKTLLLTHNVDTLGQ
MSCNPAIGGIGKGHLVKEVDAMGGLMAHAADKAGIQFRTLNSSKGPAVRATRAQADRV
LYRQAVRTALENQPNLDIFQQEATDILIEQDRVTGVSTKMGLIFRAKSVVLTAGTFLA
GKIHIGLENYEGGRAGDPASVNLSHRLRDLGLRVDRLKTGTPPRIDARTINFDILAKQ
HGDEVLPMFSFMGSVDDHPQQIPCYITYTNEQTHEVIRNNLDRSPMYTGVIEGIGPRY
CPSIEDKVMRFSDRNSHQIYLEPEGLTSNEVYPNGISTSLPFDVQMGIVNSMKGLENA
RIVKPGYAIEYDYFDPRDLKPTLETKSISGLFFAGQINGTTGYEEAAAQGLLAGINAG
LYVQEKDAWYPRRDQSYTGVLVDDLCTLGTKEPYRVFTSRAEYRLLLREDNADIRLTP
IAHELGLIDDARWARFNQKMENIEQERQRLRNIWLHPRSEYLEEANKVLGSPLVREAS
GEDLLRRPEMTYDILTSLTPYKPAMEDKEAVEQVEIAIKYQGYIEHQQEEIEKQKRHE
NTAIPANFDYSKVSSLSNEVRAKLEQHRPVSISQASRISGITPAAISIILVNLKKQGM
LKRGE"
misc_feature 11505..13379
/locus_tag="CGSHiEE_00050"
/gene_synonym="gidA"
/note="tRNA uridine 5-carboxymethylaminomethyl
modification enzyme GidA; Validated; Region: PRK05192"
/db_xref="CDD:179960"
misc_feature 11523..>11882
/locus_tag="CGSHiEE_00050"
/gene_synonym="gidA"
/note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
NADB_Rossmann; cl09931"
/db_xref="CDD:213117"
misc_feature <12486..12695
/locus_tag="CGSHiEE_00050"
/gene_synonym="gidA"
/note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
NADB_Rossmann; cl09931"
/db_xref="CDD:213117"
misc_feature 13134..13349
/locus_tag="CGSHiEE_00050"
/gene_synonym="gidA"
/note="GidA associated domain 3; Region: GIDA_assoc_3;
pfam13932"
/db_xref="CDD:206103"
gene 13570..13944
/gene="rpsL"
/locus_tag="CGSHiEE_00055"
/db_xref="GeneID:5225202"
CDS 13570..13944
/gene="rpsL"
/locus_tag="CGSHiEE_00055"
/note="interacts with and stabilizes bases of the 16S rRNA
that are involved in tRNA selection in the A site and with
the mRNA backbone; located at the interface of the 30S and
50S subunits, it traverses the body of the 30S subunit
contacting proteins on the other side; mutations in the
S12 gene confer streptomycin resistance"
/codon_start=1
/transl_table=11
/product="30S ribosomal protein S12"
/protein_id="YP_001289892.1"
/db_xref="GI:148825139"
/db_xref="GeneID:5225202"
/translation="MATINQLVRKPRVKKVVKSNVPALEACPQKRGVCTRVYTTTPKK
PNSALRKVCRIRLTNGFEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGAL
DCAGVKDRKQGRSKYGVKRPKA"
misc_feature 13576..13899
/gene="rpsL"
/locus_tag="CGSHiEE_00055"
/note="S12-like family, 30S ribosomal protein S12
subfamily; S12 is located at the interface of the large
and small ribosomal subunits of prokaryotes, chloroplasts
and mitochondria, where it plays an important role in both
tRNA and ribosomal subunit...; Region: Ribosomal_S12;
cd03368"
/db_xref="CDD:239466"
misc_feature order(13579..13584,13588..13593,13600..13605)
/gene="rpsL"
/locus_tag="CGSHiEE_00055"
/note="S17 interaction site [polypeptide binding]; other
site"
/db_xref="CDD:239466"
misc_feature 13579..13581
/gene="rpsL"
/locus_tag="CGSHiEE_00055"
/note="S8 interaction site; other site"
/db_xref="CDD:239466"
misc_feature order(13603..13611,13645..13647,13651..13656,13660..13662,
13705..13710,13714..13722,13741..13743,13765..13767,
13774..13779,13816..13821,13831..13836,13897..13899)
/gene="rpsL"
/locus_tag="CGSHiEE_00055"
/note="16S rRNA interaction site [nucleotide binding];
other site"
/db_xref="CDD:239466"
misc_feature order(13696..13701,13831..13833)
/gene="rpsL"
/locus_tag="CGSHiEE_00055"
/note="streptomycin interaction site [chemical binding];
other site"
/db_xref="CDD:239466"
misc_feature 13699..13704
/gene="rpsL"
/locus_tag="CGSHiEE_00055"
/note="23S rRNA interaction site [nucleotide binding];
other site"
/db_xref="CDD:239466"
misc_feature order(13702..13719,13777..13803)
/gene="rpsL"
/locus_tag="CGSHiEE_00055"
/note="aminoacyl-tRNA interaction site (A-site)
[nucleotide binding]; other site"
/db_xref="CDD:239466"
gene 14102..14572
/locus_tag="CGSHiEE_00060"
/db_xref="GeneID:5225183"
CDS 14102..14572
/locus_tag="CGSHiEE_00060"
/note="binds directly to 16S rRNA where it nucleates
assembly of the head domain of the 30S subunit"
/codon_start=1
/transl_table=11
/product="30S ribosomal protein S7"
/protein_id="YP_001289893.1"
/db_xref="GI:148825140"
/db_xref="GeneID:5225183"
/translation="MPRRRSVEARKILPDPKFGSELLAKFINVIMVDGKKSVAESIVY
GALETLAQRTGKEPLEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALGMR
WIVEAARKRGDKSMALRLANELSDASDNKGAAVKKREDVHRMAEANKAFAHYRW"
misc_feature 14102..14569
/locus_tag="CGSHiEE_00060"
/note="30S ribosomal protein S7; Validated; Region:
PRK05302"
/db_xref="CDD:180003"
gene 14656..16758
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/db_xref="GeneID:5225184"
CDS 14656..16758
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="EF-G; promotes GTP-dependent translocation of the
ribosome during translation; many organisms have multiple
copies of this gene"
/codon_start=1
/transl_table=11
/product="elongation factor G"
/protein_id="YP_001289894.1"
/db_xref="GI:148825141"
/db_xref="GeneID:5225184"
/translation="MARTTPIERYRNIGISAHIDAGKTTTTERILFYTGVSHKIGEVH
DGAATMDWMEQEQERGITITSAATTAFWSGMSQQFPQHRINVIDTPGHVDFTVEVERS
MRVLDGAVMVYCAVGGVQPQSETVWRQANKYEVPRIAFVNKMDRTGANFLRVVEQLKT
RLGANAIPLQLPVGAEENFTGVVDLIKMKAINWNEADQGMTFTYEEVPANMQADCEEW
RQNLVEAAAEASEELMEKYLGGEDLTEEEIKSALRQRVLANEIILVTCGSAFKNKGVQ
AMLDAVVEYLPAPTDIPAIKGINPDETEGERHASDEEPFSSLAFKIATDPFVGNLTFF
RVYSGVINSGDTVLNSVRQKRERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTG
DTLCAIDAPIILERMEFPEPVISVAVEPKTKADQEKMGLALGRLAQEDPSFRVHTDEE
SGETIISGMGELHLDIIVDRMKREFKVEANIGKPQVSYRETIRTRVNDVEGKHAKQSG
GRGQYGHVVIDLYPLDPEGPGYEFVNEIKGGVIPGEYIPAVDKGIQEQLKSGPLAGYP
VVDLGVRLHFGSYHDVDSSELAFKLAASLAFKAAFSKANPVLLEPIMKVEVETPPEYV
GDVIGDLSRRRAMVNGQEANEFVVKIDAEVPLSEMFGYATDLRSQTQGRASYSMEPLK
YAEAPTSVAAAVIEARKK"
misc_feature 14656..16755
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="elongation factor G; Reviewed; Region: PRK00007"
/db_xref="CDD:178789"
misc_feature 14689..15522
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="Elongation factor G (EF-G) family involved in both
the elongation and ribosome recycling phases of protein
synthesis; Region: EF-G; cd01886"
/db_xref="CDD:206673"
misc_feature 14704..14727
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="G1 box; other site"
/db_xref="CDD:206673"
misc_feature order(14707..14709,14713..14715,14725..14730,14737..14739,
14746..14751,14851..14856,14929..14934,15001..15006,
15112..15114,15124..15126)
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="putative GEF interaction site [polypeptide
binding]; other site"
/db_xref="CDD:206673"
misc_feature order(14713..14715,14719..14730,15079..15084,15088..15090,
15457..15465)
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="GTP/Mg2+ binding site [chemical binding]; other
site"
/db_xref="CDD:206673"
misc_feature 14794..14853
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="Switch I region; other site"
/db_xref="CDD:206673"
misc_feature 14839..14841
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="G2 box; other site"
/db_xref="CDD:206673"
misc_feature 14917..14928
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="G3 box; other site"
/db_xref="CDD:206673"
misc_feature 14923..14979
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="Switch II region; other site"
/db_xref="CDD:206673"
misc_feature 15079..15090
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="G4 box; other site"
/db_xref="CDD:206673"
misc_feature 15457..15465
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="G5 box; other site"
/db_xref="CDD:206673"
misc_feature 15598..15843
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="EFG_mtEFG_II: this subfamily represents the domain
II of elongation factor G (EF-G) in bacteria and, the
C-terminus of mitochondrial Elongation factor G1 (mtEFG1)
and G2 (mtEFG2)_like proteins found in eukaryotes. During
the process of peptide synthesis...; Region: EFG_mtEFG_II;
cd04088"
/db_xref="CDD:58095"
misc_feature 16117..16413
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="EFG_mtEFG1_IV: domains similar to domain IV of the
bacterial translational elongation factor (EF) EF-G.
Included in this group is a domain of mitochondrial
Elongation factor G1 (mtEFG1) proteins homologous to
domain IV of EF-G. Eukaryotic cells harbor 2...; Region:
EFG_mtEFG1_IV; cd01434"
/db_xref="CDD:58274"
misc_feature 16483..16716
/locus_tag="CGSHiEE_00065"
/gene_synonym="fusA"
/note="EFG_mtEFG_C: domains similar to the C-terminal
domain of the bacterial translational elongation factor
(EF) EF-G. Included in this group is the C-terminus of
mitochondrial Elongation factor G1 (mtEFG1) and G2
(mtEFG2) proteins. Eukaryotic cells harbor 2...; Region:
EFG_mtEFG_C; cd03713"
/db_xref="CDD:58065"
gene 16823..18007
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/db_xref="GeneID:5225185"
CDS 16823..18007
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/EC_number="3.6.5.3"
/note="EF-Tu; promotes GTP-dependent binding of
aminoacyl-tRNA to the A-site of ribosomes during protein
biosynthesis; when the tRNA anticodon matches the mRNA
codon, GTP hydrolysis results; the inactive EF-Tu-GDP
leaves the ribosome and release of GDP is promoted by
elongation factor Ts; many prokaryotes have two copies of
the gene encoding EF-Tu"
/codon_start=1
/transl_table=11
/product="elongation factor Tu"
/protein_id="YP_001289895.1"
/db_xref="GI:148825142"
/db_xref="GeneID:5225185"
/translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKHYGGAA
RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGA
ILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ
YDFPGDDTPIVRGSALQALNGVAEWEEKILELANHLDTYIPEPERAIDQPFLLPIEDV
FSISGRGTVVTGRVERGIIRTGDEVEIVGIKDTAKTTVTGVEMFRKLLDEGRAGENIG
ALLRGTKREEIERGQVLAKPGSITPHTDFESEVYVLSKDEGGRHTPFFKGYRPQFYFR
TTDVTGTIELPEGVEMVMPGDNIKMTVSLIHPIAMDQGLRFAIREGGRTVGAGVVAKI
IK"
misc_feature 16823..18004
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="elongation factor Tu; Reviewed; Region: PRK00049"
/db_xref="CDD:178823"
misc_feature 16853..17431
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="Elongation Factor Tu (EF-Tu) GTP-binding proteins;
Region: EF_Tu; cd01884"
/db_xref="CDD:206671"
misc_feature 16877..16900
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="G1 box; other site"
/db_xref="CDD:206671"
misc_feature order(16880..16882,16886..16888,16898..16903,16910..16912,
16919..16924,16934..16936,17018..17023,17075..17080,
17147..17152,17156..17167,17174..17176,17267..17269,
17279..17281,17357..17362)
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="GEF interaction site [polypeptide binding]; other
site"
/db_xref="CDD:206671"
misc_feature order(16886..16903,16961..16963,17228..17233,17237..17239,
17342..17350)
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="GTP/Mg2+ binding site [chemical binding]; other
site"
/db_xref="CDD:206671"
misc_feature 16988..17020
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="Switch I region; other site"
/db_xref="CDD:206671"
misc_feature 17006..17008
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="G2 box; other site"
/db_xref="CDD:206671"
misc_feature 17063..17074
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="G3 box; other site"
/db_xref="CDD:206671"
misc_feature 17069..17125
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="Switch II region; other site"
/db_xref="CDD:206671"
misc_feature 17228..17239
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="G4 box; other site"
/db_xref="CDD:206671"
misc_feature 17342..17350
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="G5 box; other site"
/db_xref="CDD:206671"
misc_feature 17453..17713
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="EFTU_II: Elongation factor Tu domain II. Elongation
factors Tu (EF-Tu) are three-domain GTPases with an
essential function in the elongation phase of mRNA
translation. The GTPase center of EF-Tu is in the
N-terminal domain (domain I), also known as the...;
Region: EFTU_II; cd03697"
/db_xref="CDD:58088"
misc_feature 17720..17989
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="Domain III of elongation factor (EF) Tu. Ef-Tu
consists of three structural domains, designated I, II and
III. Domain III adopts a beta barrel structure. Domain III
is involved in binding to both charged tRNA and binding to
elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707"
/db_xref="CDD:58073"
misc_feature order(17756..17758,17762..17770,17822..17824,17942..17950,
17978..17980)
/locus_tag="CGSHiEE_00070"
/gene_synonym="tuf"
/note="Antibiotic Binding Site [chemical binding]; other
site"
/db_xref="CDD:58073"
gene complement(18137..18424)
/locus_tag="CGSHiEE_00075"
/db_xref="GeneID:5225186"
CDS complement(18137..18424)
/locus_tag="CGSHiEE_00075"
/note="COG2168 Uncharacterized conserved protein involved
in oxidation of intracellular sulfur"
/codon_start=1
/transl_table=11
/product="elongation factor G"
/protein_id="YP_001289896.1"
/db_xref="GI:148825143"
/db_xref="GeneID:5225186"
/translation="MLYTFSQSDYPKTELDDYFSYITEKDAVVLWQDGVLLAIKYPDY
FAKCKGNCMILKQDILARNLTALLPQSSKIKLISIEELVGITENYLPQLSL"
misc_feature complement(18140..18424)
/locus_tag="CGSHiEE_00075"
/note="Uncharacterized conserved protein involved in
oxidation of intracellular sulfur [Inorganic ion transport
and metabolism]; Region: DsrH; COG2168"
/db_xref="CDD:32351"
gene complement(18433..18792)
/locus_tag="CGSHiEE_00080"
/db_xref="GeneID:5225187"
CDS complement(18433..18792)
/locus_tag="CGSHiEE_00080"
/note="in Escherichai coli the heterohexameric TusBCD
complex is involved in sulfur related that results in
thiouridation to U34 position in some tRNAs"
/codon_start=1
/transl_table=11
/product="sulfur relay protein TusC"
/protein_id="YP_001289897.1"
/db_xref="GI:148825144"
/db_xref="GeneID:5225187"
/translation="MKIAFLFRTSPHGTSISREGLDAILAATAFCEPNDIGIFFIDDG
VLNLIDNQQPEIIQQKDFIRAFKLLDLYDVEQRFICTASLQKFKLDNRELILSCEKID
RSLLLEKLNQAEKLFTF"
misc_feature complement(18436..18792)
/locus_tag="CGSHiEE_00080"
/note="sulfur relay protein TusC; Validated; Region:
PRK00211"
/db_xref="CDD:178930"
gene complement(18789..19169)
/locus_tag="CGSHiEE_00085"
/db_xref="GeneID:5224905"
CDS complement(18789..19169)
/locus_tag="CGSHiEE_00085"
/note="in Escherichai coli the heterohexameric TusBCD
complex is involved in sulfur related that results in
thiouridation to U34 position in some tRNAs"
/codon_start=1
/transl_table=11
/product="sulfur transfer complex subunit TusD"
/protein_id="YP_001289898.1"
/db_xref="GI:148825145"
/db_xref="GeneID:5224905"
/translation="MRYVIAVKSPIYGKQGAFLAYQFANALIKKGHEISQIFFFQDGV
SNGNALVYPANDEVNLQKHWQMFSITHNVPLHLCVAASQRRGVVDNLTTPTTAHYNLA
EGFIIAGLGEFIAASLNADRVITL"
misc_feature complement(18792..19169)
/locus_tag="CGSHiEE_00085"
/note="sulfur transfer complex subunit TusD; Validated;
Region: PRK00207"
/db_xref="CDD:178928"
gene complement(19169..19834)
/locus_tag="CGSHiEE_00090"
/db_xref="GeneID:5224906"
CDS complement(19169..19834)
/locus_tag="CGSHiEE_00090"
/note="COG2964 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289899.1"
/db_xref="GI:148825146"
/db_xref="GeneID:5224906"
/translation="MTLNDKYPFTDEDQAIINSYKAVVDGVSALIGEHCEIVLHSLEN
IEHSAICIANGHNTNRQVGSPITDLALRSLRNMQSESVSKPYFTRAKGSVLMKSVTIA
IRNKTQRIIGLLCININLDVPMSQFLQCFMPTEHTNETSSVNFANSVEDLVAQTIEKT
IEEVNADRAVANNTKNRQIVLSLYEKGIFDIKDAINLVAERLDISRHTVYLYIRQIKQ
EQE"
misc_feature complement(19172..19816)
/locus_tag="CGSHiEE_00090"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG2964"
/db_xref="CDD:32784"
misc_feature complement(19448..19789)
/locus_tag="CGSHiEE_00090"
/note="YheO-like PAS domain; Region: PAS_6; pfam08348"
/db_xref="CDD:116929"
misc_feature complement(19193..19384)
/locus_tag="CGSHiEE_00090"
/note="HTH domain; Region: HTH_22; pfam13309"
/db_xref="CDD:205489"
gene complement(19924..20649)
/locus_tag="CGSHiEE_00095"
/db_xref="GeneID:5224907"
CDS complement(19924..20649)
/locus_tag="CGSHiEE_00095"
/note="COG0545 FKBP-type peptidyl-prolyl cis-trans
isomerases 1"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289900.1"
/db_xref="GI:148825147"
/db_xref="GeneID:5224907"
/translation="MLKIQKLSIAALMVSAVISGQVFAEDNTFDEKAASYAVGTLMGS
QMKDLVDSHKEVIKYDNARILDGLKDALEGKVDVRKDEKIQKTLESIEAKLVAASKAK
AEAIAKQAKEEGDKFRAEFAKGKDVKTTQSGLMYKIESAGKGDTIKSTDTVKVHYTGK
LPNGKVFDSSVERGQPVEFQLDQVIKGWTEGLQLVKKGGKIQLVIAPELGYGEQGAGA
SIPPNSTLIFDVEVLDVNPKSEK"
misc_feature complement(20236..20613)
/locus_tag="CGSHiEE_00095"
/note="Domain amino terminal to FKBP-type peptidyl-prolyl
isomerase; Region: FKBP_N; pfam01346"
/db_xref="CDD:189949"
misc_feature complement(19942..20568)
/locus_tag="CGSHiEE_00095"
/note="FKBP-type peptidyl-prolyl cis-trans isomerases 1
[Posttranslational modification, protein turnover,
chaperones]; Region: FkpA; COG0545"
/db_xref="CDD:30891"
misc_feature complement(19951..20217)
/locus_tag="CGSHiEE_00095"
/note="FKBP-type peptidyl-prolyl cis-trans isomerase;
Region: FKBP_C; pfam00254"
/db_xref="CDD:201116"
gene 20747..20968
/locus_tag="CGSHiEE_00100"
/db_xref="GeneID:5224908"
CDS 20747..20968
/locus_tag="CGSHiEE_00100"
/note="COG2900 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289901.1"
/db_xref="GI:148825148"
/db_xref="GeneID:5224908"
/translation="MQIQQMLENRIEELEMKIAFQEQLLDELNHALVQQQFDIDKMQV
QLRYMANKLKDFQPSNIASQSEETPPPHY"
misc_feature 20747..20965
/locus_tag="CGSHiEE_00100"
/note="hypothetical protein; Provisional; Region:
PRK02119"
/db_xref="CDD:167317"
gene complement(21060..21785)
/locus_tag="CGSHiEE_00105"
/db_xref="GeneID:5224909"
CDS complement(21060..21785)
/locus_tag="CGSHiEE_00105"
/note="COG0678 Peroxiredoxin"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289902.1"
/db_xref="GI:148825149"
/db_xref="GeneID:5224909"
/translation="MSNMEGKKVPQMTFRTRQGDKWVDVTTSELFDNKTVIVFSLPGA
FTPTCSSSHLPRYNELAPVFKKYGVDDILVVSVNDTFVMNAWKEDEKSENITFIPDGN
GEFTEGMGMLVGKEDLGFGKRSWRYSMLVKNGVVEKMFIEPNEPGDPFKVSDADTMLK
YLAPQHQVQESISIFTKPGCPFCAKAKQLLHDKGLSFEEIILGHDATIVSVRAVSGRA
TVPQVFIGGKHIGGSDDLEKYFA"
misc_feature complement(<21345..21785)
/locus_tag="CGSHiEE_00105"
/note="Peroxiredoxin [Posttranslational modification,
protein turnover, chaperones]; Region: AhpC; COG0450"
/db_xref="CDD:30799"
misc_feature complement(21306..21773)
/locus_tag="CGSHiEE_00105"
/note="Peroxiredoxin (PRX) family, PRX5-like subfamily;
members are similar to the human protein, PRX5, a
homodimeric TRX peroxidase, widely expressed in tissues
and found cellularly in mitochondria, peroxisomes and the
cytosol. The cellular location of PRX5...; Region:
PRX5_like; cd03013"
/db_xref="CDD:48562"
misc_feature complement(order(21408..21410,21639..21641,21648..21650))
/locus_tag="CGSHiEE_00105"
/note="catalytic triad [active]"
/db_xref="CDD:48562"
misc_feature complement(order(21417..21419,21480..21485,21543..21545,
21549..21551,21645..21647))
/locus_tag="CGSHiEE_00105"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:48562"
misc_feature complement(21063..21278)
/locus_tag="CGSHiEE_00105"
/note="Glutaredoxin (GRX) family, PRX5 hybrid subfamily;
composed of hybrid proteins containing peroxiredoxin (PRX)
and GRX domains, which is found in some pathogenic
bacteria and cyanobacteria. PRXs are thiol-specific
antioxidant (TSA) proteins that confer a...; Region:
GRX_hybridPRX5; cd03029"
/db_xref="CDD:48578"
misc_feature complement(order(21126..21131,21240..21248,21255..21257))
/locus_tag="CGSHiEE_00105"
/note="GSH binding site [chemical binding]; other site"
/db_xref="CDD:48578"
misc_feature complement(order(21237..21239,21246..21248))
/locus_tag="CGSHiEE_00105"
/note="catalytic residues [active]"
/db_xref="CDD:48578"
gene 21909..22814
/locus_tag="CGSHiEE_00110"
/db_xref="GeneID:5226279"
CDS 21909..22814
/locus_tag="CGSHiEE_00110"
/note="Activates the expression of a regulon of hydrogen
peroxide-inducible genes such as katG, gor, ahpC, ahpF,
oxyS, dps, fur and grxA"
/codon_start=1
/transl_table=11
/product="DNA-binding transcriptional regulator OxyR"
/protein_id="YP_001289903.1"
/db_xref="GI:148825150"
/db_xref="GeneID:5226279"
/translation="MNIRDLEYLVALSEYKHFRRAADSCNVSQPTLSGQIRKLEDELG
IILLERTSRKVLFTQSGMLLVDQARTVLREVKLLKEMASNQGKEMTGPLHIGLIPTVG
PYLLPYIVPMLKAAFPDLEVFLYEAQTHQLLEQLETGRLDCAIVATVPETEAFIEVPI
FNEKMLLAVSEHHPWAQESKLPMNQLNGQEMLMLDDGHCLRNQALDYCFTAGAKENSH
FQATSLETLRNMVAANAGITFMPELAVLNEGTRKGVKYIPCYSPEPSRTIALVYRPGS
PLRNRYERVASAVSDEVKSILDGLK"
misc_feature 21909..22802
/locus_tag="CGSHiEE_00110"
/note="DNA-binding transcriptional regulator OxyR;
Provisional; Region: PRK11151"
/db_xref="CDD:182999"
misc_feature 21915..22091
/locus_tag="CGSHiEE_00110"
/note="Bacterial regulatory helix-turn-helix protein, lysR
family; Region: HTH_1; pfam00126"
/db_xref="CDD:201021"
misc_feature 22179..22775
/locus_tag="CGSHiEE_00110"
/note="The C-terminal substrate-binding domain of the
LysR-type transcriptional regulator OxyR, a member of the
type 2 periplasmic binding fold protein superfamily;
Region: PBP2_OxyR; cd08411"
/db_xref="CDD:176103"
misc_feature order(22215..22217,22224..22229,22236..22238,22248..22250,
22272..22286,22563..22565,22572..22577,22584..22586,
22593..22598,22602..22607)
/locus_tag="CGSHiEE_00110"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:176103"
gene 22814..23431
/locus_tag="CGSHiEE_00115"
/db_xref="GeneID:5226280"
CDS 22814..23431
/locus_tag="CGSHiEE_00115"
/note="negatively controls the expression of fabA and
fabB, genes involved in the unsaturated fatty acid
biosynthesis"
/codon_start=1
/transl_table=11
/product="DNA-binding transcriptional repressor FabR"
/protein_id="YP_001289904.1"
/db_xref="GI:148825151"
/db_xref="GeneID:5226280"
/translation="MAGVRAVQKEKTRRALVDAAFNQLSAEKSFSNLSLREVAREAGI
APTSFYRHFSDMDELGLEMVDEAGLMLRQLMRQARKRIDAGGSVISVSVDTFFEFITN
STNVFRLLLRESSGTSQAFRTAAAREIKHFVDELAEYISYKHQYSQYVAYVQAEGIVT
IVFTAGANALDMSKAEREQLKARVILQLRMLAKGADFAANKERGK"
misc_feature 22814..23398
/locus_tag="CGSHiEE_00115"
/note="DNA-binding transcriptional repressor FabR;
Provisional; Region: PRK11202"
/db_xref="CDD:183037"
misc_feature 22859..23002
/locus_tag="CGSHiEE_00115"
/note="Bacterial regulatory proteins, tetR family; Region:
TetR_N; pfam00440"
/db_xref="CDD:201228"
gene complement(23501..23977)
/gene="greB"
/locus_tag="CGSHiEE_00120"
/db_xref="GeneID:5226281"
CDS complement(23501..23977)
/gene="greB"
/locus_tag="CGSHiEE_00120"
/note="necessary for efficient RNA polymerase
transcription elongation past template-encoded arresting
sites; arresting sites in DNA have the property of
trapping a certain fraction of elongating RNA polymerases
that pass through, resulting in locked ternary complexes.
Cleavage of the nascent transcript by cleavage factors
such as GreA or GreB allows the resumption of elongation
from the new 3'terminus"
/codon_start=1
/transl_table=11
/product="transcription elongation factor GreB"
/protein_id="YP_001289905.1"
/db_xref="GI:148825152"
/db_xref="GeneID:5226281"
/translation="MAKSNYITRQGWLVLDQELKFLWKEERPKVTQAVSDAAALGDRS
ENAEYIYGKRRLREIDRRVRFLTKRLEVLQIVDYNPKQEGKVFFGAWVELENEEGEIK
QYRIVGCDEFAPAKNWISIDSPVARALIGKTLDDEVRVETPSGFITLYINKIWYEK"
misc_feature complement(23507..23977)
/gene="greB"
/locus_tag="CGSHiEE_00120"
/note="transcription elongation factor GreB; Reviewed;
Region: greB; PRK01885"
/db_xref="CDD:179345"
misc_feature complement(23753..23965)
/gene="greB"
/locus_tag="CGSHiEE_00120"
/note="Transcription elongation factor, N-terminal;
Region: GreA_GreB_N; pfam03449"
/db_xref="CDD:190636"
misc_feature complement(23510..23737)
/gene="greB"
/locus_tag="CGSHiEE_00120"
/note="Transcription elongation factor, GreA/GreB, C-term;
Region: GreA_GreB; pfam01272"
/db_xref="CDD:201702"
gene 24073..26385
/gene="greB"
/locus_tag="CGSHiEE_00125"
/db_xref="GeneID:5226282"
CDS 24073..26385
/gene="greB"
/locus_tag="CGSHiEE_00125"
/note="COG2183 Transcriptional accessory protein"
/codon_start=1
/transl_table=11
/product="transcription elongation factor GreB"
/protein_id="YP_001289906.1"
/db_xref="GI:148825153"
/db_xref="GeneID:5226282"
/translation="MLNQQISQIIAAELTVQPQQILAAIQLLDDGNTIPFIARYRKEA
TGGLDDTQLRHFETRLIYLRELEERRQTILKSIEEQGKLTDELRDKIHATQSKTELED
LYLPYKPKRRTKGQIAIEAGLEPLANLLWNEPKNDPESTALSFVDADKGVTDTKVALD
GARYILMERFAEDAGLLAKVRDYLAKNAVIVSKVIEGKETEGAKFQDYFDHQELLKNV
PSHRALAMFRGRNEGILQLSLNADPDAEEGSRQSYCEEIIRDYLDVRFTGQPADKWRE
QVIAWTWKIKVSLHLETELMASLREKAEEEAIDVFARNLTALLMAAPAGAKSTMGLDP
GLRTGVKVAVVDNTGKLLDTTTIYPHTGREAEAQVAIFSLIRKHNVELIAIGNGTASR
ETERFAKEVIKEIKENKPQTVVVSEAGASVYSASEFAANEFPNLDVSLRGAVSIARRL
QDPLAELVKIEPKAIGVGQYQHDVNQSQLARKLDAVVEDCVNAVGVDLNTASAPLLAR
VAGMTKTLAQNIVEYRDENGRFESRRELKKVPRLGPKAFEQCAGFMRIAGGKNPLDAS
GVHPEAYPVVEKILQATAQSIQDLMGNSGVVRQLDAKQFIDEQFGLPTVQDIFKELEK
PGRDPRGEFKTAVFAEGVEEITDLKSGMILEGTVTNVTNFGAFVDIGVHQDGLVHISS
LSDKFVEDPHQVVKTGNIVKVKVLEVDVPRKRIALTMRLDESAVKNDSKSDRTLSARP
RGNTQREDRNSRGNNAMGNAFADALKNWKK"
misc_feature 24073..26376
/gene="greB"
/locus_tag="CGSHiEE_00125"
/note="Transcriptional accessory protein [Transcription];
Region: Tex; COG2183"
/db_xref="CDD:32366"
misc_feature 24100..24678
/gene="greB"
/locus_tag="CGSHiEE_00125"
/note="Tex-like protein N-terminal domain; Region: Tex_N;
pfam09371"
/db_xref="CDD:150144"
misc_feature 25051..25344
/gene="greB"
/locus_tag="CGSHiEE_00125"
/note="Likely ribonuclease with RNase H fold; Region:
YqgFc; smart00732"
/db_xref="CDD:128971"
misc_feature 26023..26226
/gene="greB"
/locus_tag="CGSHiEE_00125"
/note="S1_Tex: The C-terminal S1 domain of a transcription
accessory factor called Tex, which has been characterized
in Bordetella pertussis and Pseudomonas aeruginosa. The
tex gene is essential in Bortella pertusis and is named
for its role in toxin expression; Region: S1_Tex; cd05685"
/db_xref="CDD:88440"
misc_feature order(26047..26049,26071..26073,26101..26103,26107..26109)
/gene="greB"
/locus_tag="CGSHiEE_00125"
/note="RNA binding site [nucleotide binding]; other site"
/db_xref="CDD:88440"
gene 26511..28931
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/db_xref="GeneID:5226283"
CDS 26511..28931
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="negatively supercoils closed circular
double-stranded DNA"
/codon_start=1
/transl_table=11
/product="DNA gyrase subunit B"
/protein_id="YP_001289907.1"
/db_xref="GI:148825154"
/db_xref="GeneID:5226283"
/translation="MSETTNDNYGASSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMV
FEVVDNAIDEALAGHCSDIIVTIHDDNSVSVQDDGRGIPVDIHPEEGVSAAEVIMTVL
HAGGKFDDNSYKVSGGLHGVGVSVVNALSDKLQLTIRRQGHVHEQFYHLGEPQAPLTV
IGNTETTGTTVRFWPSSDIFAITTFDYKILAKRLRELSFLNSGVSIRLIDKRDGAEDH
FHYEGGIQAFVEYLNKNKNPIHPKPFYFTAEKDGIGVEVALQWNDGVNENVYCFTNNI
PQRDGGTHLAGFRGALTRSLNSYMENEGMLKKEKVATSGDDAREGLVAIISVKVPDPK
FSSQTKDKLVSSEVKSAVESAMNEKMQEYLLENPADAKIIVNQIIMAARAREAARKAR
EMTRRKGVLDIAGLPGKLADCQEKDPALSELYLVEGDSAGGSAKVGRDRKTQAILPLK
GKILNVEKARFDKMLSSQEVGTLITALGCGIGRDEYNPDKLRYHHIIIMTDADVDGSH
IRTLLLTFFYRQMPELIERGYVYIAQPPLYKVKKGKQERYIKDADEMEQYELTLALDG
AELHISANAPAMNALVFEKLVAEYNSVQKLIGRLSRHYPAPVLKGLIYQSPISVEMMK
DESAVENWGKSFVEQLTAKETEAHQYSVRTQFNAERQVYEAVITVRKHGIDTDYFLNF
DFVHGNEYAKIVSLNKQLNGLLEEGAYVIRGEKVQPVRTFEQAVEWLVKESRKGLEVQ
RYKGLGEMNADQLWETTMDPNSRRMLKVSIKDAVAADQLFTTLMGDEVEPRREFIELN
ALRANLDV"
misc_feature 26517..28928
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="DNA gyrase subunit B; Provisional; Region: gyrB;
PRK14939"
/db_xref="CDD:184903"
misc_feature 26628..>26777
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="Histidine kinase-like ATPases; This family includes
several ATP-binding proteins for example: histidine
kinase, DNA gyrase B, topoisomerases, heat shock protein
HSP90, phytochrome-like ATPases and DNA mismatch repair
proteins; Region: HATPase_c; cd00075"
/db_xref="CDD:28956"
misc_feature 26658..26660
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="Mg2+ binding site [ion binding]; other site"
/db_xref="CDD:28956"
misc_feature order(26745..26747,26751..26753)
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="G-X-G motif; other site"
/db_xref="CDD:28956"
misc_feature 27177..27647
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="TopoIIA_Trans_DNA_gyrase: Transducer domain, having
a ribosomal S5 domain 2-like fold, of the type found in
proteins of the type IIA family of DNA topoisomerases
similar to the B subunits of E. coli DNA gyrase and E.
coli Topoisomerase IV which are; Region:
TopoII_Trans_DNA_gyrase; cd00822"
/db_xref="CDD:48467"
misc_feature 27330..27332
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="anchoring element; other site"
/db_xref="CDD:48467"
misc_feature order(27504..27506,27513..27518,27522..27524)
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:48467"
misc_feature order(27522..27524,27528..27530)
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:48467"
misc_feature 27771..28115
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM)
nucleotidyl transferase/hydrolase domain of the type found
in proteins of the type IIA family of DNA topoisomerases
similar to the Escherichia coli GyrB subunit. TopoIIA
enzymes cut both strands of the...; Region:
TOPRIM_TopoIIA_GyrB; cd03366"
/db_xref="CDD:173786"
misc_feature order(27789..27794,27801..27803,28011..28013,28017..28019,
28023..28025)
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="active site"
/db_xref="CDD:173786"
misc_feature order(27789..27791,28011..28013)
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="putative metal-binding site [ion binding]; other
site"
/db_xref="CDD:173786"
misc_feature 28704..28898
/gene="gyrB"
/locus_tag="CGSHiEE_00130"
/note="DNA gyrase B subunit, carboxyl terminus; Region:
DNA_gyraseB_C; pfam00986"
/db_xref="CDD:201537"
gene 29078..29752
/locus_tag="CGSHiEE_00135"
/db_xref="GeneID:5226284"
CDS 29078..29752
/locus_tag="CGSHiEE_00135"
/EC_number="5.1.3.1"
/note="catalyzes the interconversion of D-ribulose
5-phosphate to xylulose 5-phosphate"
/codon_start=1
/transl_table=11
/product="ribulose-phosphate 3-epimerase"
/protein_id="YP_001289908.1"
/db_xref="GI:148825155"
/db_xref="GeneID:5226284"
/translation="MKPYLIAPSILSADLARLGDDVQNVLNAGADVIHFDVMDNHYVP
NLTFGPAVCQALRDYGITAPIDVHLMVKPVDRIIPDFAKAGANYITFHPESSEHIDRS
LQLIRDCGCKSGLVFNPATPLSYLDYVLDKVDVVLLMSVNPGFGGQSFIPATLKKLQQ
ARKIIDESGYDIRLEVDGGVKVDNIAEIAAAGADMFVAGSAIFGKPDYKQVIDQMRTQ
LASVIA"
misc_feature 29090..29725
/locus_tag="CGSHiEE_00135"
/note="Ribulose-5-phosphate 3-epimerase (RPE). This enzyme
catalyses the interconversion of D-ribulose 5-phosphate
(Ru5P) into D-xylulose 5-phosphate, as part of the Calvin
cycle (reductive pentose phosphate pathway) in
chloroplasts and in the oxidative pentose...; Region: RPE;
cd00429"
/db_xref="CDD:73366"
misc_feature 29093..29725
/locus_tag="CGSHiEE_00135"
/note="ribulose-phosphate 3-epimerase; Region: rpe;
TIGR01163"
/db_xref="CDD:130231"
misc_feature order(29102..29104,29108..29110,29183..29185,29285..29287,
29504..29509,29513..29518,29606..29608,29612..29614,
29672..29677)
/locus_tag="CGSHiEE_00135"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:73366"
misc_feature order(29123..29125,29132..29134,29192..29194,29198..29203,
29207..29209,29213..29224,29294..29296,29306..29308,
29369..29371,29375..29380,29432..29434,29441..29443,
29447..29449,29459..29461,29501..29503,29528..29530,
29534..29536,29546..29548)
/locus_tag="CGSHiEE_00135"
/note="hexamer interface [polypeptide binding]; other
site"
/db_xref="CDD:73366"
misc_feature order(29177..29179,29183..29185,29279..29281,29606..29608)
/locus_tag="CGSHiEE_00135"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:73366"
gene 29798..30472
/locus_tag="CGSHiEE_00140"
/db_xref="GeneID:5224727"
CDS 29798..30472
/locus_tag="CGSHiEE_00140"
/note="catalyzes the dephosphorylation of
2-phosphoglycolate to form glycolate and phosphate"
/codon_start=1
/transl_table=11
/product="phosphoglycolate phosphatase"
/protein_id="YP_001289909.1"
/db_xref="GI:148825156"
/db_xref="GeneID:5224727"
/translation="MNTQFKLIGFDLDGTLVNSLPDLALSVNSALAELNLPQAPEELV
LTWIGNGAPVLIARALDWAQKQTGKVLTEEEIKQVTERFNFHYGENLCNVSRLYPNVK
ETLETLKEKGYILSVVTNKPTKHVQPVLAAFGIDHLFSEMLGGQSLPAIKPHPAPLYY
LCGKFGFEPRQVLFVGDSKNDIIAGHAAGCAVVGLTYGYNYNIPIRESNPDWVFDDFA
QLLTIL"
misc_feature 29798..30469
/locus_tag="CGSHiEE_00140"
/note="phosphoglycolate phosphatase; Provisional; Region:
PRK13222"
/db_xref="CDD:183901"
misc_feature 29825..>30211
/locus_tag="CGSHiEE_00140"
/note="Haloacid Dehalogenase-like Hydrolases; Region:
HAD_like; cl11391"
/db_xref="CDD:212620"
misc_feature 30044..30379
/locus_tag="CGSHiEE_00140"
/note="Haloacid dehalogenase-like hydrolases. The haloacid
dehalogenase-like (HAD) superfamily includes L-2-haloacid
dehalogenase, epoxide hydrolase, phosphoserine
phosphatase, phosphomannomutase, phosphoglycolate
phosphatase, P-type ATPase, and many others; Region:
HAD_like; cd01427"
/db_xref="CDD:119389"
misc_feature 30152..30154
/locus_tag="CGSHiEE_00140"
/note="motif II; other site"
/db_xref="CDD:119389"
gene 30563..30916
/locus_tag="CGSHiEE_00145"
/db_xref="GeneID:5224728"
CDS 30563..30916
/locus_tag="CGSHiEE_00145"
/codon_start=1
/transl_table=11
/product="transposase"
/protein_id="YP_001289910.1"
/db_xref="GI:148825157"
/db_xref="GeneID:5224728"
/translation="MGKHYTIEFKLQALQPILNGKMSIREAARFYNIPSNALVGTWLK
RFEKSGIKGLIPRKPSGRPPMKPKYAKMPPPPKTEEDRLRLRILQLEAEVAYLKELRK
LRLQDEAEQQKLSKG"
misc_feature 30587..30748
/locus_tag="CGSHiEE_00145"
/note="Helix-turn-helix domain; Region: HTH_28; pfam13518"
/db_xref="CDD:205696"
gene 31084..31200
/locus_tag="CGSHiEE_00150"
/db_xref="GeneID:5224729"
CDS 31084..31200
/locus_tag="CGSHiEE_00150"
/note="COG2963 Transposase and inactivated derivatives"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289911.1"
/db_xref="GI:148825158"
/db_xref="GeneID:5224729"
/translation="MPGVNHIVESWLNMASFKVCREKGIAWTMKRWKVSLGD"
gene 31113..31352
/locus_tag="CGSHiEE_00155"
/db_xref="GeneID:5224730"
CDS 31113..31352
/locus_tag="CGSHiEE_00155"
/EC_number="5.1.3.1"
/note="COG2801 Transposase and inactivated derivatives"
/codon_start=1
/transl_table=11
/product="ribulose-phosphate 3-epimerase"
/protein_id="YP_001289912.1"
/db_xref="GI:148825159"
/db_xref="GeneID:5224730"
/translation="MAEHGIIQSMSRKGNCLDNEAMESFFGRLKTECFYGREFNSREE
IVDAVRDYLDYYNHRRIQLKLKGLSPIQYRKQSFK"
misc_feature <31113..31211
/locus_tag="CGSHiEE_00155"
/note="Integrase core domain; Region: rve; pfam00665"
/db_xref="CDD:201381"
misc_feature 31179..31346
/locus_tag="CGSHiEE_00155"
/note="Integrase core domain; Region: rve_2; pfam13333"
/db_xref="CDD:205513"
gene complement(31415..32407)
/locus_tag="CGSHiEE_00160"
/db_xref="GeneID:5224731"
CDS complement(31415..32407)
/locus_tag="CGSHiEE_00160"
/EC_number="6.3.1.1"
/note="catalyzes the formation of asparagine from
aspartate and ammonia"
/codon_start=1
/transl_table=11
/product="asparagine synthetase AsnA"
/protein_id="YP_001289913.1"
/db_xref="GI:148825160"
/db_xref="GeneID:5224731"
/translation="MKKTFILQQQEISFVKNTFTQNLIEQLGIIEVQGPILSQVGNGM
QDNLSGIEKAVQVNVKCIPNAVFEVVHSLAKWKRHTLARFNFKEDEGLFVHMKALRPD
EDSLDPTHSVYVDQWDWEKVIPEGRRNFAYLKETVNSIYRAIRLTELAVEARFDIPSI
LPKQITFVHSEDLVKRYPDLSSKERENAICKEYGAVFLIGIGGKLSDGKPHDGRAPDY
DDWTTESENGYKGLNGDILVWNDQLGKAFELSSMGIRVDQSALRLQAGLTGDEDRLKM
DWHQDLLNGKLPLTIGGGIGQSRLAMLLLRKKHIGEVQSSVWPKEMLEEFSNIL"
misc_feature complement(31430..32383)
/locus_tag="CGSHiEE_00160"
/note="Asparagine synthetase (aspartate-ammonia ligase)
(AsnA) catalyses the conversion of L-aspartate to
L-asparagine in the presence of ATP and ammonia. AsnA is
a homodimeric enzyme which is structurally similiar to the
catalytic core domain of class II...; Region: AsnA;
cd00645"
/db_xref="CDD:29808"
misc_feature complement(order(31439..31441,31457..31459,31469..31471,
32096..32098,32102..32107,32117..32119,32156..32158,
32168..32170,32207..32209,32228..32230,32234..32236,
32240..32242,32309..32314,32369..32371,32378..32383))
/locus_tag="CGSHiEE_00160"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:29808"
misc_feature complement(order(31511..31513,31643..31645,31655..31657,
31664..31666,31703..31705,32048..32050,32054..32056,
32060..32062,32108..32110,32177..32179,32186..32188))
/locus_tag="CGSHiEE_00160"
/note="active site"
/db_xref="CDD:29808"
gene 32561..33013
/locus_tag="CGSHiEE_00165"
/db_xref="GeneID:5225114"
CDS 32561..33013
/locus_tag="CGSHiEE_00165"
/note="transcriptional repressor of asnA which codes for
aspartate-ammonia ligase"
/codon_start=1
/transl_table=11
/product="DNA-binding transcriptional regulator AsnC"
/protein_id="YP_001289914.1"
/db_xref="GI:148825161"
/db_xref="GeneID:5225114"
/translation="MHNIDSLDQKILRVLTKDARTPYAEMAKNFGVSPGTIHVRVEKM
RQSGIIKGTKVIIDERKLGYDVCCFIGIILKSAKDYEKVIKKLESFDEVVEAYYTTGN
YSIFLKVMTHTIAELHSVLATKIQLIDEIQSTETLISMQNPILRDIKP"
misc_feature 32561..33010
/locus_tag="CGSHiEE_00165"
/note="DNA-binding transcriptional regulator AsnC;
Provisional; Region: PRK11179"
/db_xref="CDD:183019"
misc_feature 32573..>32722
/locus_tag="CGSHiEE_00165"
/note="Arsenical Resistance Operon Repressor and similar
prokaryotic, metal regulated homodimeric repressors. ARSR
subfamily of helix-turn-helix bacterial transcription
regulatory proteins (winged helix topology). Includes
several proteins that appear to...; Region: HTH_ARSR;
cd00090"
/db_xref="CDD:28974"
misc_feature order(32576..32584,32621..32626,32630..32632,32657..32668,
32672..32677,32684..32689,32693..32698,32714..32722)
/locus_tag="CGSHiEE_00165"
/note="putative DNA binding site [nucleotide binding];
other site"
/db_xref="CDD:28974"
misc_feature order(32621..32623,32633..32635)
/locus_tag="CGSHiEE_00165"
/note="putative Zn2+ binding site [ion binding]; other
site"
/db_xref="CDD:28974"
misc_feature 32768..32983
/locus_tag="CGSHiEE_00165"
/note="AsnC family; Region: AsnC_trans_reg; pfam01037"
/db_xref="CDD:189815"
gene complement(33039..33434)
/locus_tag="CGSHiEE_00170"
/db_xref="GeneID:5225115"
CDS complement(33039..33434)
/locus_tag="CGSHiEE_00170"
/note="COG1188 Ribosome-associated heat shock protein
implicated in the recycling of the 50S subunit (S4
paralog)"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289915.1"
/db_xref="GI:148825162"
/db_xref="GeneID:5225115"
/translation="MAEKEVRLDKWLWAARFYKTRSIAKAMIESGKVHYNNQRAKVSK
IVEVGAMLKLRQGNEEKEIKIIALSDQRRGAPEAQLLYQETESNVKKREEIAWARKNN
SLSMPHPDRRPNKKERRDLLKFKHQDKFE"
misc_feature complement(33243..33419)
/locus_tag="CGSHiEE_00170"
/note="S4/Hsp/ tRNA synthetase RNA-binding domain; The
domain surface is populated by conserved, charged residues
that define a likely RNA-binding site; Found in stress
proteins, ribosomal proteins and tRNA synthetases; This
may imply a hitherto unrecognized...; Region: S4; cd00165"
/db_xref="CDD:29105"
misc_feature complement(order(33294..33296,33300..33314,33315..33320,
33339..33341,33345..33350,33357..33362,33366..33371,
33375..33380,33414..33416))
/locus_tag="CGSHiEE_00170"
/note="RNA binding surface [nucleotide binding]; other
site"
/db_xref="CDD:29105"
gene 33666..35654
/locus_tag="CGSHiEE_00175"
/db_xref="GeneID:5225116"
CDS 33666..35654
/locus_tag="CGSHiEE_00175"
/note="COG1297 Predicted membrane protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289916.1"
/db_xref="GI:148825163"
/db_xref="GeneID:5225116"
/translation="MYNENLKELTVRGIILGALITVIFTASNVYLGLKVGVTFASSIP
AAVISMAVLKFFKDSSILENNMVQTQASSAGTLSSVIFVLPGLLMMGYWQDFPFWQTM
LICAAGGTLGVLFTIPLRRAMVVNSNLPYPEGVAAAEILKAGNHADGDSGVKDIAYGG
VLAGLVAFLTNGLRVMADGASAWIQTGKAAFQLPMGFSLALLGAGYLIGIVGGIAMLI
GVILTWGVAVPYFTMSEDIAADASLIDSAMTVWKTKVRYIGVGTIGIAAIWTLLILMK
PMIEGMVHSFRMLKGGQEASEHRIDIDLSPKTMIYILIATVALIVISLHHFIAAAPIS
PELSILLVVVCTFLAVFIGFFVAAASGYMAGLVGSSSSPISGIGIISVIVISLVLVSI
GNASGLFETVDGQKFLTALTLFTASIVITTACISNDNLQDLKTGLLVEATPWRQQVAL
IIGCFVGALVIAPVLEILYHAYGFSGALPRPDMDPSQALSAPQATLMTAISQGIFTNK
LEWTYILTGVGLGAVLITIDAFLKKVSNKVFSLPVIAVGIGIYLPPSINTPVIVGAFL
AWIMARHIAKLGNKEVSAKAERFGTLFSAGLIVGESLMGVILAFIIAASVTTGGSEAP
LSLNLENWDTIGEWLGLIVFIVGIVIFASRVLRAKKSD"
misc_feature 33678..35513
/locus_tag="CGSHiEE_00175"
/note="oligopeptide transporters, OPT superfamily; Region:
OPT_sfam; TIGR00728"
/db_xref="CDD:200045"
misc_feature 33687..35504
/locus_tag="CGSHiEE_00175"
/note="putative oligopeptide transporter, OPT family;
Region: TIGR00733"
/db_xref="CDD:129816"
gene 35707..36123
/locus_tag="CGSHiEE_00180"
/db_xref="GeneID:5225117"
CDS 35707..36123
/locus_tag="CGSHiEE_00180"
/note="COG1175 ABC-type sugar transport systems, permease
components"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289917.1"
/db_xref="GI:148825164"
/db_xref="GeneID:5225117"
/translation="MKSYLKTLIFFPLILQIVVTALLIWFDDDSSGVIVPFSSYALTA
FLLATIPAFLTALLAAKFRYTRYNIASIVLVSSIISFVYCNMASYFYLLLLGEQDTSF
WGWLIEGGLSLGLISTCGMVFYALFVMPWLLPKTRE"
gene 36128..36937
/locus_tag="CGSHiEE_00185"
/db_xref="GeneID:5225118"
CDS 36128..36937
/locus_tag="CGSHiEE_00185"
/note="COG1218 3'-Phosphoadenosine 5'-phosphosulfate
(PAPS) 3'-phosphatase"
/codon_start=1
/transl_table=11
/product="DNA-binding transcriptional regulator AsnC"
/protein_id="YP_001289918.1"
/db_xref="GI:148825165"
/db_xref="GeneID:5225118"
/translation="MLTLNEHLLNQVLLIAYQAGKHLQQFYQKQVHVELKEDNTPVTE
ADLFVSQFLTEKLTALFPNIPVLSEENCHISFEERKNWKEYWLIDPLDGTQQFINRTD
QFSVLITLVRKNKPVLSVIHAPILSTTYYAMRDFGAFKKQLDQVKKLTKNTTNFDRPL
RIAVGATTSQEKVRSILPKDFTCEFVVVGSSSLKSGLVAEGAVDCYVRLGQTGEWDTA
GAEVLLNETHGAIFDSHFEPLTYNQRETLINPHFVMVGDQSFDWRSVFQFN"
misc_feature 36149..36889
/locus_tag="CGSHiEE_00185"
/note="CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate
(PAPS) 3'-phosphatase, is a bacterial member of the
inositol monophosphatase family. It has been proposed that
CysQ helps control intracellular levels of PAPS, which is
an intermediate in cysteine...; Region: CysQ; cd01638"
/db_xref="CDD:30136"
misc_feature order(36263..36265,36332..36337,36392..36409,36413..36415,
36620..36622,36629..36631,36707..36709,36743..36745,
36770..36775)
/locus_tag="CGSHiEE_00185"
/note="active site"
/db_xref="CDD:30136"
gene 37013..38497
/locus_tag="CGSHiEE_00190"
/db_xref="GeneID:5225119"
CDS 37013..38497
/locus_tag="CGSHiEE_00190"
/EC_number="1.1.1.49"
/note="catalyzes the formation of D-glucono-1,5-lactone
6-phosphate from D-glucose 6-phosphate"
/codon_start=1
/transl_table=11
/product="glucose-6-phosphate 1-dehydrogenase"
/protein_id="YP_001289919.1"
/db_xref="GI:148825166"
/db_xref="GeneID:5225119"
/translation="MQTDNNCIVIFGASGDLTHRKLIPALYNLYKIGRLSENFSVLGV
ARSDLNDETFRKKMREALIHNEETTPDTLDAFCSHLYYQAVNTSDAQDYGKLVPRLDE
LHDKYQTCGNTLYYMSTPPSLYGVIPECLAAHGLNTEEYGWKRIIVEKPFGYDEKTAQ
ALDVQIHRFFEEHQIYRIDHYLGKETVQNLLVLRFSNGWFEPLWNRNFIDYVEITGAE
SIGVEERGGYYDGSGAMRDMFQNHLLQVLAMVAMEPPAIINANSMRDEVAKVMHSLRP
LTSEDMENNLVLGQYTAAEINGKMEKGYLEEKGVPADSRTETYISLRCEIENWRWAGV
PFYVRTGKRLPARVTEIVIHFKTTPHPVFSQNAPENKLIIRIQPDEAISMRFGLKKPG
AGFEAKEVSMDFRYADLAGTQVLTAYERLLLDAMKGDATLFARTDAVHAAWKFVQPIL
DYKANGGRIHEYEAGTWGPVAADKLIAKQGKVWRKPSGLMKKKV"
misc_feature 37013..38470
/locus_tag="CGSHiEE_00190"
/note="glucose-6-phosphate 1-dehydrogenase; Validated;
Region: PRK05722"
/db_xref="CDD:180222"
misc_feature 37037..37579
/locus_tag="CGSHiEE_00190"
/note="Glucose-6-phosphate dehydrogenase, NAD binding
domain; Region: G6PD_N; pfam00479"
/db_xref="CDD:201252"
misc_feature 37583..38470
/locus_tag="CGSHiEE_00190"
/note="Glucose-6-phosphate dehydrogenase, C-terminal
domain; Region: G6PD_C; pfam02781"
/db_xref="CDD:202392"
gene 38582..39280
/locus_tag="CGSHiEE_00195"
/db_xref="GeneID:5225209"
CDS 38582..39280
/locus_tag="CGSHiEE_00195"
/note="COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate
isomerase/deaminase"
/codon_start=1
/transl_table=11
/product="6-phosphogluconolactonase"
/protein_id="YP_001289920.1"
/db_xref="GI:148825167"
/db_xref="GeneID:5225209"
/translation="MNYISFPTAQHAVDKIAQEFVIYSQLNHPVHISLSGGSTPKLLF
KTLAKSPYAEQINWKNLHFWWGDDRMVPPSDPESNYGEVQKLLFDHIQIPTENIHRIR
GENEPHFELKRFEEELSAVIPNGVFDWIILGMGTDGHTASLFPHQTNFDDENLAVIAK
HPESGQIRISKTAKLIEQAKRITYLVTGESKADILKEIQTTPAENLPYPAAKIKAKNG
VTEWYLDKAAAQLL"
misc_feature 38606..39253
/locus_tag="CGSHiEE_00195"
/note="6PGL: 6-Phosphogluconolactonase (6PGL) subfamily;
6PGL catalyzes the second step of the oxidative phase of
the pentose phosphate pathway, the hydrolyzation of
6-phosphoglucono-1,5-lactone (delta form) to
6-phosphogluconate. 6PGL is thought to guard...; Region:
6PGL; cd01400"
/db_xref="CDD:73166"
misc_feature order(38693..38698,38786..38788,38996..38998,39083..39085,
39152..39154)
/locus_tag="CGSHiEE_00195"
/note="putative active site [active]"
/db_xref="CDD:73166"
gene 39291..39737
/locus_tag="CGSHiEE_00200"
/db_xref="GeneID:5225210"
CDS 39291..39737
/locus_tag="CGSHiEE_00200"
/codon_start=1
/transl_table=11
/product="virulence-associated protein D"
/protein_id="YP_001289921.1"
/db_xref="GI:148825168"
/db_xref="GeneID:5225210"
/translation="MDRTLIVFDMDTHCLERYYHNPSWRNAYADIQRILKKHGFMNIQ
GTVYLSDVGIKQAHGTLALQEVAARFEWFAACASNIQFYELKDDFNAQFIVDGVQRAR
EAFQRSLDSLRQELLQAGLPANKVEEIVGKRQFSLQQIQENSVSQD"
misc_feature 39297..39584
/locus_tag="CGSHiEE_00200"
/note="Uncharacterized virulence-associated protein D
[Function unknown]; Region: VapD; COG3309"
/db_xref="CDD:33118"
gene 39885..40667
/locus_tag="CGSHiEE_00205"
/db_xref="GeneID:5225211"
CDS 39885..40667
/locus_tag="CGSHiEE_00205"
/EC_number="1.1.1.49"
/note="COG3309 Uncharacterized virulence-associated
protein D"
/codon_start=1
/transl_table=11
/product="glucose-6-phosphate 1-dehydrogenase"
/protein_id="YP_001289922.1"
/db_xref="GI:148825169"
/db_xref="GeneID:5225211"
/translation="MTEWYLDKASAKNLDIEMLLVKRYQDIFKENQEIIDALLSNSNL
SKIHLGFVPDDFKKKKHRILIVGRETRGWDLKYLEKYDQNSVYQLMDLSKSWVIRNLE
RSDSVNKKGKCFFNFFRKVSQENPNASILWANIFCVSYKKSNPSKIDTKSVFANIKKI
SESLLKAQIEILQPNIIIFASGLDTQAILARRDYFKNDLKPSGKSVVPGLDKKYLEQF
HLLENYGEDILCYRTVHPSSRTKNSVIALKELRKILKSKTMN"
gene 40687..42141
/locus_tag="CGSHiEE_00210"
/db_xref="GeneID:5225212"
CDS 40687..42141
/locus_tag="CGSHiEE_00210"
/EC_number="1.1.1.44"
/note="catalyzes the formation of D-ribulose 5-phosphate
from 6-phospho-D-gluconate"
/codon_start=1
/transl_table=11
/product="6-phosphogluconate dehydrogenase"
/protein_id="YP_001289923.1"
/db_xref="GI:148825170"
/db_xref="GeneID:5225212"
/translation="MSVKGDIGVIGLAVMGQNLILNMNDHGFKVVAYNRTTSKVDEFL
QGAAKGTNIIGAYSLEDLAAKLEKPRKVMLMVRAGDVVDQFIEALLPHLEEGDIIIDG
GNSNYPDTNRRVKALAEKGIRFIGSGVSGGEEGARHGPSIMPGGNQEAWQYVKPIFQA
ISAKTEQGEPCCDWVGGEGAGHFVKMVHNGIEYGDMQLICEAYQFLKEGLGLSYDEMQ
AIFAEWKNTELDSYLIDITTDILGYKDASGEPLVEKILDTAGQKGTGKWTGINALDFG
IPLTLITESVFARCVSSFKDQRVAANQLFGKTITPVEGDKKVWIEAVRKALLASKIIS
YAQGFMLIREASEQFGWDINYGATALLWREGCIIRSRFLGNIRDAYEANPNLVFLGSD
SYFKGILENALSDWRKVVAKSIEVGIPMPCMASAITFLDGYTSARLPANLLQAQRDYF
GAHTYERTDKPRGEFFHTNWTGRGGNIASTTYDV"
misc_feature 40702..41604
/locus_tag="CGSHiEE_00210"
/note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
NADB_Rossmann; cl09931"
/db_xref="CDD:213117"
misc_feature 40729..42108
/locus_tag="CGSHiEE_00210"
/note="6-phosphogluconate dehydrogenase; Validated;
Region: PRK09287"
/db_xref="CDD:181758"
misc_feature 41227..42099
/locus_tag="CGSHiEE_00210"
/note="6-phosphogluconate dehydrogenase, C-terminal
domain; Region: 6PGD; pfam00393"
/db_xref="CDD:109451"
gene complement(42267..42890)
/locus_tag="CGSHiEE_00215"
/db_xref="GeneID:5225213"
CDS complement(42267..42890)
/locus_tag="CGSHiEE_00215"
/EC_number="1.1.1.44"
/note="COG0362 6-phosphogluconate dehydrogenase"
/codon_start=1
/transl_table=11
/product="6-phosphogluconate dehydrogenase"
/protein_id="YP_001289924.1"
/db_xref="GI:148825171"
/db_xref="GeneID:5225213"
/translation="MLSLTTESCELFNIPFYQFAQMKKFCPENIPAIKADYKLHWDNW
KAIIQSVSAQLGTPFAKPHIESWTNGWQVRTHFFAYFKYEFNQNSAAIFSVLLNRRRL
RVCLDWHCYRADRSQINVQQYNQWLDQFDFKQFADFEIWREDESEYDDFRQVKVISEK
NLILRSDEDFWCIGKSIEKAELNQIDPVLFITHTIQQLQPLYDRCHQ"
misc_feature complement(42273..42884)
/locus_tag="CGSHiEE_00215"
/note="Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49);
Region: G6PD_bact; pfam10786"
/db_xref="CDD:151242"
gene complement(42900..43727)
/gene="apaH"
/locus_tag="CGSHiEE_00220"
/db_xref="GeneID:5225228"
CDS complement(42900..43727)
/gene="apaH"
/locus_tag="CGSHiEE_00220"
/EC_number="3.6.1.41"
/note="hydrolyzes P(1),P(4)-bis(5'-adenosyl)
tetraphosphate to form 2 ADP"
/codon_start=1
/transl_table=11
/product="diadenosine tetraphosphatase"
/protein_id="YP_001289925.1"
/db_xref="GI:148825172"
/db_xref="GeneID:5225228"
/translation="MATYFVGDLQGCYDELQLLLERVDFNPTQDKLYLVGDLVARGDK
SLECLRFVKSLGNAAQTVLGNHDLHLIATALDIKKVKPRDRVDAIFNAPDFDEQIHWL
RHQPLLVHSEELNFLMSHAGISPDWDLKTAKSCAAEVEQILQHGDFHYLIENMYSEQP
DRWSPDLQGLARHRYIINAFTRMRFCYLDHRFDFACKSPLKDAPAELTPWFNLDNPLY
KQIPIVFGHWASLVDEPTPKGIYALDTGCVWNNRMTMLRWEDKQFFTQSAVKNYSDF"
misc_feature complement(42903..43727)
/gene="apaH"
/locus_tag="CGSHiEE_00220"
/note="bis(5'-nucleosyl)-tetraphosphatase (symmetrical);
Region: apaH; TIGR00668"
/db_xref="CDD:161988"
misc_feature complement(42951..43721)
/gene="apaH"
/locus_tag="CGSHiEE_00220"
/note="Escherichia coli ApaH and related proteins,
metallophosphatase domain; Region: MPP_ApaH; cd07422"
/db_xref="CDD:163665"
misc_feature complement(order(42981..42983,42996..42998,43047..43049,
43368..43370,43530..43535,43605..43610,43617..43619,
43698..43700,43704..43706))
/gene="apaH"
/locus_tag="CGSHiEE_00220"
/note="active site"
/db_xref="CDD:163665"
misc_feature complement(order(43047..43049,43368..43370,43533..43535,
43617..43619,43698..43700,43704..43706))
/gene="apaH"
/locus_tag="CGSHiEE_00220"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:163665"
gene 43846..44754
/gene="apaH"
/locus_tag="CGSHiEE_00225"
/db_xref="GeneID:5225229"
CDS 43846..44754
/gene="apaH"
/locus_tag="CGSHiEE_00225"
/EC_number="3.6.1.41"
/note="COG3306 Glycosyltransferase involved in LPS
biosynthesis"
/codon_start=1
/transl_table=11
/product="diadenosine tetraphosphatase"
/protein_id="YP_001289926.1"
/db_xref="GI:148825173"
/db_xref="GeneID:5225229"
/translation="MSAIENIVISMENATERRKHITKQFESKKLSFSFFNAYTYQSIN
QSINQSINQSINQSINQSINQSINQSNSILHNIEESRILTKGEKGCLISHFLLWNKCV
NENLEYLKIFEDDVILGENAEVFLNQNEWLKTRFDFNDIFIIRLETFLQPVKLEKQTK
IPPFNSRNFDILKSTHWGTAGYIISQGAAKYVIEYLKNIPSDEIVAVDQLIFNKLVDV
DNYIVYQLNPAICIQELQANQSKSVLTSGLEKERQKRPKIRKKKTLKQRLTRIKENII
RALNRKKWKEQQRIKEMQGKEIVRFM"
misc_feature 43867..>44208
/gene="apaH"
/locus_tag="CGSHiEE_00225"
/note="Glycosyltransferase family 25 [lipooligosaccharide
(LOS) biosynthesis protein] is a family of
glycosyltransferases involved in LOS biosynthesis. The
members include the beta(1,4) galactosyltransferases: Lgt2
of Moraxella catarrhalis, LgtB and LgtE of...; Region:
Glyco_transf_25; cd06532"
/db_xref="CDD:133474"
gene complement(44793..45656)
/gene="ksgA"
/locus_tag="CGSHiEE_00230"
/db_xref="GeneID:5225230"
CDS complement(44793..45656)
/gene="ksgA"
/locus_tag="CGSHiEE_00230"
/note="catalyzes the transfer of a total of four methyl
groups from S-adenosyl-l-methionine (S-AdoMet) to two
adjacent adenosine bases A1518 and A1519 in 16S rRNA;
mutations in ksgA causes resistance to the translation
initiation inhibitor kasugamycin"
/codon_start=1
/transl_table=11
/product="dimethyladenosine transferase"
/protein_id="YP_001289927.1"
/db_xref="GI:148825174"
/db_xref="GeneID:5225230"
/translation="MNSKKHLGHTARKRFGQNFLHDTSVIQGIVAAIYPQPNQFLVEI
GPGLGALTEPVGELVDHLTVVELDRDLAERLRHHPFLHQKLTVIETDAMQFDFGALYT
KENLAEKGQKLRVFGNLPYNISTPLMFHLFKYHDVIQDMHFMLQKEVVKRLCAAPNSK
AYGRLTIMAQYFCQVMPVLEVPPSAFKPAPKVDSAVVRLIPHKELPHPVKDLYWLNRV
CSQAFNQRRKTLRNALSTLFSPENLTALGIDLNARAENLAIADYARLANWLADNPPAD
INKDEILDSEE"
misc_feature complement(44838..45656)
/gene="ksgA"
/locus_tag="CGSHiEE_00230"
/note="16S ribosomal RNA methyltransferase KsgA/Dim1
family protein; Reviewed; Region: ksgA; PRK00274"
/db_xref="CDD:178953"
gene complement(45740..46735)
/locus_tag="CGSHiEE_00235"
/db_xref="GeneID:5225231"
CDS complement(45740..46735)
/locus_tag="CGSHiEE_00235"
/note="COG0438 Glycosyltransferase"
/codon_start=1
/transl_table=11
/product="lipooligosaccharide glycosyl transferase G"
/protein_id="YP_001289928.1"
/db_xref="GI:148825175"
/db_xref="GeneID:5225231"
/translation="MERYLLDIVNGLSKTNITPKIYSAKFDTALPEYDLINPVKINLS
FVPKKWRTSFLSYFSNKYKEISEVSLTTSYTLSDVVICGGNHKGYLQASKKKPSISDR
FKIMGEQKSLNQSKYVIAHSALMKKELVELYHISENKIDVIYPPINTDKFTQIDEYRR
EQLREKLGFKKDEIIYLFPSTGHTRKGFDILKQYFENTQLPIRLVVAGTPVEESPKIS
SLGFCKNMPELYQAADFTIMASQYEPFGLVGLESILSGTPVIFSENMGCLEVLQNEFG
YTFSRENMNTLDDAIQKSVKQASEHQHRILNPMDCIRYDPSLSHHIKTILELIAK"
misc_feature complement(45857..46735)
/locus_tag="CGSHiEE_00235"
/note="This family is most closely related to the GT1
family of glycosyltransferases and named after YqgM in
Bacillus licheniformis about which little is known.
Glycosyltransferases catalyze the transfer of sugar
moieties from activated donor molecules to...; Region:
GT1_YqgM_like; cd03801"
/db_xref="CDD:99974"
misc_feature complement(46280..46732)
/locus_tag="CGSHiEE_00235"
/note="Glycosyltransferase Family 4; Region:
Glyco_transf_4; pfam13439"
/db_xref="CDD:205617"
misc_feature complement(45743..>46456)
/locus_tag="CGSHiEE_00235"
/note="Glycosyltransferase [Cell envelope biogenesis,
outer membrane]; Region: RfaG; COG0438"
/db_xref="CDD:30787"
gene complement(46823..47659)
/gene="ksgA"
/locus_tag="CGSHiEE_00240"
/db_xref="GeneID:5225232"
CDS complement(46823..47659)
/gene="ksgA"
/locus_tag="CGSHiEE_00240"
/note="COG3306 Glycosyltransferase involved in LPS
biosynthesis"
/codon_start=1
/transl_table=11
/product="dimethyladenosine transferase"
/protein_id="YP_001289929.1"
/db_xref="GI:148825176"
/db_xref="GeneID:5225232"
/translation="MQKPFLSKYDPQMHINYVISLTSAYQRREHIQKEFSQQNIPFEF
FDALKPSKELTSLIEKFIPNLLHAKLTEGEKACFMSHYMLWQKCLSEDLPYIYIFEDN
VLLGENADKFLAEDEWLEERFKQTDKFILRFETFLNFSKCKDKKIKPYSGRKILKLVS
ENCGAAGYVISREAVKQLSAHICSLTSNHLLAIDLLMFNIFNQSTYQVSPGVCVQEGQ
LYPKDIKLHSQLETERQKYLSVKKKRTLKTVLISLAGKPKKILRKIYRKLFISKHIVP
FR"
misc_feature complement(47318..47614)
/gene="ksgA"
/locus_tag="CGSHiEE_00240"
/note="Glycosyltransferase family 25 [lipooligosaccharide
(LOS) biosynthesis protein] is a family of
glycosyltransferases involved in LOS biosynthesis. The
members include the beta(1,4) galactosyltransferases: Lgt2
of Moraxella catarrhalis, LgtB and LgtE of...; Region:
Glyco_transf_25; cd06532"
/db_xref="CDD:133474"
gene 47795..48013
/gene="infA"
/locus_tag="CGSHiEE_00245"
/db_xref="GeneID:5225233"
CDS 47795..48013
/gene="infA"
/locus_tag="CGSHiEE_00245"
/note="stimulates the activities of the other two
initiation factors, IF-2 and IF-3"
/codon_start=1
/transl_table=11
/product="translation initiation factor IF-1"
/protein_id="YP_001289930.1"
/db_xref="GI:148825177"
/db_xref="GeneID:5225233"
/translation="MAKEDCIEMQGTILETLPNTMFRVELENGHVVTAHISGKMRKNY
IRILTGDKVTVEMTPYDLSKGRIIFRSR"
misc_feature 47813..48004
/gene="infA"
/locus_tag="CGSHiEE_00245"
/note="S1_IF1: Translation Initiation Factor IF1, S1-like
RNA-binding domain. IF1 contains an S1-like RNA-binding
domain, which is found in a wide variety of RNA-associated
proteins. Translation initiation includes a number of
interrelated steps preceding the...; Region: S1_IF1;
cd04451"
/db_xref="CDD:88417"
misc_feature order(47837..47845,47861..47863,47897..47899,47906..47911,
47924..47935,47984..47986,47990..47992)
/gene="infA"
/locus_tag="CGSHiEE_00245"
/note="rRNA binding site [nucleotide binding]; other site"
/db_xref="CDD:88417"
misc_feature order(47897..47899,47909..47911,48002..48004)
/gene="infA"
/locus_tag="CGSHiEE_00245"
/note="predicted 30S ribosome binding site; other site"
/db_xref="CDD:88417"
gene complement(48010..48135)
/locus_tag="CGSHiEE_00250"
/db_xref="GeneID:5226182"
CDS complement(48010..48135)
/locus_tag="CGSHiEE_00250"
/note="COG0361 Translation initiation factor 1 (IF-1)"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289931.1"
/db_xref="GI:148825178"
/db_xref="GeneID:5226182"
/translation="MWLRVADYTDFFTFRNQFEFFLNKKEDRYYNNIGLSQIFCD"
gene 48212..48589
/gene="rpsF"
/locus_tag="CGSHiEE_00255"
/db_xref="GeneID:5226183"
CDS 48212..48589
/gene="rpsF"
/locus_tag="CGSHiEE_00255"
/note="binds cooperatively with S18 to the S15-16S
complex, allowing platform assembly to continue with S11
and S21"
/codon_start=1
/transl_table=11
/product="30S ribosomal protein S6"
/protein_id="YP_001289932.1"
/db_xref="GI:148825179"
/db_xref="GeneID:5226183"
/translation="MRHYEIVFMVHPDQSEQVPGMIERYTGSVKEAGGQVHRLEDWGR
RQLAYPINKLHKAHYVLMNVEVPQQVIDELETTFRYNDAVLRSLVIHTKHAVTEASPM
KAAKEERKPLAEVENNDFEDAEE"
misc_feature 48212..48532
/gene="rpsF"
/locus_tag="CGSHiEE_00255"
/note="30S ribosomal protein S6; Reviewed; Region: rpsF;
PRK00453"
/db_xref="CDD:179034"
gene 48576..48902
/locus_tag="CGSHiEE_00260"
/db_xref="GeneID:5226184"
CDS 48576..48902
/locus_tag="CGSHiEE_00260"
/note="binds single-stranded DNA at the primosome assembly
site"
/codon_start=1
/transl_table=11
/product="primosomal replication protein N"
/protein_id="YP_001289933.1"
/db_xref="GI:148825180"
/db_xref="GeneID:5226184"
/translation="MLKSNLKIDNRFSVMGVVSQLPKRLKSPSGIEHCKFLLEHRSDQ
IESGFTRQAWLKMPVQISGNQLIEKTQSITVGSKILVVGFITSHKTQSGLCQLVLHAE
QIEFID"
misc_feature 48609..48896
/locus_tag="CGSHiEE_00260"
/note="SSB_OBF: A subfamily of OB folds similar to the OB
fold of ssDNA-binding protein (SSB). SSBs bind with high
affinity to ssDNA. They bind to and protect ssDNA
intermediates during DNA metabolic pathways. All bacterial
and eukaryotic SSBs studied to date...; Region: SSB_OBF;
cd04496"
/db_xref="CDD:72968"
misc_feature order(48609..48620,48693..48701,48738..48740,48744..48746,
48807..48809,48834..48836,48861..48863,48864..48866)
/locus_tag="CGSHiEE_00260"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:72968"
misc_feature order(48624..48632,48648..48650,48678..48680,48699..48704,
48732..48737,48741..48743,48747..48749,48753..48755,
48759..48761,48798..48803,48825..48827,48831..48833,
48837..48842,48867..48869,48873..48875)
/locus_tag="CGSHiEE_00260"
/note="ssDNA binding site [nucleotide binding]; other
site"
/db_xref="CDD:72968"
misc_feature order(48807..48809,48813..48815,48819..48821,48888..48890)
/locus_tag="CGSHiEE_00260"
/note="tetramer (dimer of dimers) interface [polypeptide
binding]; other site"
/db_xref="CDD:72968"
gene 48915..49142
/gene="rpsR"
/locus_tag="CGSHiEE_00265"
/db_xref="GeneID:5226185"
CDS 48915..49142
/gene="rpsR"
/locus_tag="CGSHiEE_00265"
/note="binds as a heterodimer with protein S6 to the
central domain of the 16S rRNA; helps stabilize the
platform of the 30S subunit"
/codon_start=1
/transl_table=11
/product="30S ribosomal protein S18"
/protein_id="YP_001289934.1"
/db_xref="GI:148825181"
/db_xref="GeneID:5226185"
/translation="MARYFRRRKFCRFTAENVVEIDYKDIATLKNYISESGKIVPSRI
TGTRAKYQRQLARAIKRARYLALLPYTDNHQ"
misc_feature 48915..49130
/gene="rpsR"
/locus_tag="CGSHiEE_00265"
/note="30S ribosomal protein S18; Reviewed; Region: rpsR;
PRK00391"
/db_xref="CDD:178997"
gene 49159..49608
/gene="rplI"
/locus_tag="CGSHiEE_00270"
/db_xref="GeneID:5226186"
CDS 49159..49608
/gene="rplI"
/locus_tag="CGSHiEE_00270"
/note="in Escherichia coli this protein is wrapped around
the base of the L1 stalk"
/codon_start=1
/transl_table=11
/product="50S ribosomal protein L9"
/protein_id="YP_001289935.1"
/db_xref="GI:148825182"
/db_xref="GeneID:5226186"
/translation="MQVILLDKIVHLGQVGDQVNVKSGFARNFLIPQGKAVMATKANI
EHFEARRAELEATAAANLAAAQARAAEVTALGSVTIASKAGDEGRLFGAITTRDVAEA
VTAAGVKIAKSEVRLPNGPIRTLGDHDVRFQLHGEVFAALDVIVVAE"
misc_feature 49159..49605
/gene="rplI"
/locus_tag="CGSHiEE_00270"
/note="50S ribosomal protein L9; Reviewed; Region: rplI;
PRK00137"
/db_xref="CDD:178893"
misc_feature 49159..49302
/gene="rplI"
/locus_tag="CGSHiEE_00270"
/note="Ribosomal protein L9, N-terminal domain; Region:
Ribosomal_L9_N; pfam01281"
/db_xref="CDD:201708"
misc_feature 49387..49605
/gene="rplI"
/locus_tag="CGSHiEE_00270"
/note="Ribosomal protein L9, C-terminal domain; Region:
Ribosomal_L9_C; pfam03948"
/db_xref="CDD:146531"
gene complement(49782..51428)
/gene="groEL"
/locus_tag="CGSHiEE_00275"
/db_xref="GeneID:5225427"
CDS complement(49782..51428)
/gene="groEL"
/locus_tag="CGSHiEE_00275"
/note="60 kDa chaperone family; promotes refolding of
misfolded polypeptides especially under stressful
conditions; forms two stacked rings of heptamers to form a
barrel-shaped 14mer; ends can be capped by GroES;
misfolded proteins enter the barrel where they are
refolded when GroES binds; many bacteria have multiple
copies of the groEL gene which are active under different
environmental conditions; the B.japonicum protein in this
cluster is expressed constitutively; in Rhodobacter,
Corynebacterium and Rhizobium this protein is essential
for growth"
/codon_start=1
/transl_table=11
/product="chaperonin GroEL"
/protein_id="YP_001289936.1"
/db_xref="GI:148825183"
/db_xref="GeneID:5225427"
/translation="MAAKDVKFGNDARVKMLKGVNVLADAVKVTLGPKGRNVILDKSF
GAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVNE
GLKAVAAGMNPMDLKRGIDKAVSAVVSELKNLSKPCETAKEIEQVGTISANSDSIVGQ
LISQAMEKVGKEGVITVEDGTGLEDELDVVEGMQFDRGYLSPYFINKPETATVELDNP
YLLLVDKKISNIRELLPVLEGVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAV
KAPGFGDRRKAMLQDIAILTAGTVISEEIGMELEKATLEDLGQAKRVVINKDNTTIID
GIGDEAQIKGRVAQIRQQIEESTSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEK
KDRVDDALHATRAAVEEGIVAGGGVALVRAAAKVAASLKGDNEEQNVGIKLALRAMEA
PLRQIVTNAGEEASVVASAVKNGEGNFGYNAGTEQYGDMIEMGILDPTKVTRSALQFA
ASVAGLMITTECMVTDLPKDDKADLGAAGMGGMGGMGGMM"
misc_feature complement(49836..51425)
/gene="groEL"
/locus_tag="CGSHiEE_00275"
/note="chaperonin GroEL; Reviewed; Region: groEL;
PRK12849"
/db_xref="CDD:183791"
misc_feature complement(49857..51419)
/gene="groEL"
/locus_tag="CGSHiEE_00275"
/note="GroEL_like type I chaperonin. Chaperonins are
involved in productive folding of proteins. They share a
common general morphology, a double toroid of 2 stacked
rings, each composed of 7-9 subunits. The symmetry of type
I is seven-fold and they are found...; Region: GroEL;
cd03344"
/db_xref="CDD:48161"
misc_feature complement(order(49860..49880,49887..49889,50049..50051,
50271..50273,50277..50279,50658..50660,50742..50744,
50838..50840,51201..51203,51210..51212,51222..51224,
51246..51248,51252..51254,51282..51284,51288..51293,
51306..51308,51312..51323,51354..51356,51405..51407,
51417..51419))
/gene="groEL"
/locus_tag="CGSHiEE_00275"
/note="ring oligomerisation interface [polypeptide
binding]; other site"
/db_xref="CDD:48161"
misc_feature complement(order(49941..49943,49947..49949,50064..50066,
50181..50183,50235..50237,50979..50981,51156..51158,
51168..51170,51330..51338))
/gene="groEL"
/locus_tag="CGSHiEE_00275"
/note="ATP/Mg binding site [chemical binding]; other site"
/db_xref="CDD:48161"
misc_feature complement(order(50025..50027,50034..50039,50043..50045,
50070..50072,50124..50126,51102..51104))
/gene="groEL"
/locus_tag="CGSHiEE_00275"
/note="stacking interactions; other site"
/db_xref="CDD:48161"
misc_feature complement(order(50196..50201,50304..50306,50850..50852,
50871..50873,51006..51008))
/gene="groEL"
/locus_tag="CGSHiEE_00275"
/note="hinge regions; other site"
/db_xref="CDD:48161"
gene complement(51451..51741)
/gene="groES"
/locus_tag="CGSHiEE_00280"
/db_xref="GeneID:5225428"
CDS complement(51451..51741)
/gene="groES"
/locus_tag="CGSHiEE_00280"
/note="10 kDa chaperonin; Cpn10; GroES; forms
homoheptameric ring; binds to one or both ends of the
GroEL double barrel in the presence of adenine nucleotides
capping it; folding of unfolded substrates initiates in a
GroEL-substrate bound and capped by GroES; release of the
folded substrate is dependent on ATP binding and
hydrolysis in the trans ring"
/codon_start=1
/transl_table=11
/product="co-chaperonin GroES"
/protein_id="YP_001289937.1"
/db_xref="GI:148825184"
/db_xref="GeneID:5225428"
/translation="MNIRPLHDRVIIKREEVETRSAGGIVLTGSAATKSTRAKVLAVG
KGRILENGTVQPLDVKVGDTVIFNDGYGVKSEKIDGEEVLIISENDILAIVE"
misc_feature complement(51457..51738)
/gene="groES"
/locus_tag="CGSHiEE_00280"
/note="Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10
cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase,
to assist the folding and assembly of proteins and is
found in eubacterial cytosol, as well as in the matrix of
mitochondria and chloroplasts. It...; Region: cpn10;
cd00320"
/db_xref="CDD:73192"
misc_feature complement(order(51460..51468,51514..51516,51523..51525,
51538..51540,51568..51570,51631..51636,51715..51717,
51724..51726,51730..51732,51736..51738))
/gene="groES"
/locus_tag="CGSHiEE_00280"
/note="oligomerisation interface [polypeptide binding];
other site"
/db_xref="CDD:73192"
misc_feature complement(51649..51690)
/gene="groES"
/locus_tag="CGSHiEE_00280"
/note="mobile loop; other site"
/db_xref="CDD:73192"
misc_feature complement(order(51574..51576,51607..51609))
/gene="groES"
/locus_tag="CGSHiEE_00280"
/note="roof hairpin; other site"
/db_xref="CDD:73192"
gene 51907..52209
/gene="ureA"
/locus_tag="CGSHiEE_00285"
/db_xref="GeneID:5225429"
CDS 51907..52209
/gene="ureA"
/locus_tag="CGSHiEE_00285"
/EC_number="3.5.1.5"
/note="UreA, with UreB and UreC catalyzes the hydrolysis
of urea into ammonia and carbon dioxide; nickel
metalloenzyme; accessory proteins UreD, UreE, UreF, and
UreG are necessary for assembly of the metallocenter"
/codon_start=1
/transl_table=11
/product="urease subunit gamma"
/protein_id="YP_001289938.1"
/db_xref="GI:148825185"
/db_xref="GeneID:5225429"
/translation="MHLTSREQEKLMLFLAGELAAKRKARGVKLNYPETIAYIASHLQ
EAARDGMSVAEVMQYGSTLLTVDDVMEGVAEMVHEVQIEATFPDGTKLVTVHNPIR"
misc_feature 51916..52203
/gene="ureA"
/locus_tag="CGSHiEE_00285"
/note="Urease gamma-subunit; Urease is a nickel-dependent
metalloenzyme that catalyzes the hydrolysis of urea to
form ammonia and carbon dioxide. Nickel-dependent ureases
are found in bacteria, archaea, fungi and plants. Their
primary role is to allow the use...; Region: Urease_gamma;
cd00390"
/db_xref="CDD:63883"
misc_feature order(51931..51936,51961..51963,51973..51975,51997..52005,
52024..52026,52117..52119,52132..52134,52147..52149,
52153..52155)
/gene="ureA"
/locus_tag="CGSHiEE_00285"
/note="alpha-gamma subunit interface [polypeptide
binding]; other site"
/db_xref="CDD:63883"
misc_feature 52117..52119
/gene="ureA"
/locus_tag="CGSHiEE_00285"
/note="beta-gamma subunit interface [polypeptide binding];
other site"
/db_xref="CDD:63883"
gene 52286..52591
/gene="ureB"
/locus_tag="CGSHiEE_00290"
/db_xref="GeneID:5225430"
CDS 52286..52591
/gene="ureB"
/locus_tag="CGSHiEE_00290"
/EC_number="3.5.1.5"
/note="ureases catalyze the hydrolysis of urea into
ammonia and carbon dioxide; in Helicobacter pylori and
Yersinia enterocolitica the ammonia released plays a key
role in bacterial survival by neutralizing acids when
colonizing the gastric mucosa; the holoenzyme is composed
of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella
suis the urease encoded by this operon (one of two
urease-encoding operons found in its genome) is involved
with urease activity, optimum growth, resistance to low-pH
killing in-vitro and persistence in-vivo, while the other
operon does not seem to be active"
/codon_start=1
/transl_table=11
/product="urease subunit beta"
/protein_id="YP_001289939.1"
/db_xref="GI:148825186"
/db_xref="GeneID:5225430"
/translation="MIPGEYQLAEGDILANVGRKTVKIEVTNSGDRPIQVGSHYHFFE
TNNALKFDRTLARGMRLNVPSGNAVRFEPGEVKSVELVAFGGNQIIYGFHNQIDGKL"
misc_feature 52286..52588
/gene="ureB"
/locus_tag="CGSHiEE_00290"
/note="Urease beta-subunit; Urease is a nickel-dependent
metalloenzyme that catalyzes the hydrolysis of urea to
form ammonia and carbon dioxide. Nickel-dependent ureases
are found in bacteria, archaea, fungi and plants. Their
primary role is to allow the use of...; Region:
Urease_beta; cd00407"
/db_xref="CDD:73201"
misc_feature 52286..52288
/gene="ureB"
/locus_tag="CGSHiEE_00290"
/note="gamma-beta subunit interface [polypeptide binding];
other site"
/db_xref="CDD:73201"
misc_feature order(52289..52312,52316..52333,52400..52402,52463..52465,
52469..52471,52475..52483,52538..52552,52556..52564)
/gene="ureB"
/locus_tag="CGSHiEE_00290"
/note="alpha-beta subunit interface [polypeptide binding];
other site"
/db_xref="CDD:73201"
gene 52603..54321
/gene="ureC"
/locus_tag="CGSHiEE_00295"
/db_xref="GeneID:5225431"
CDS 52603..54321
/gene="ureC"
/locus_tag="CGSHiEE_00295"
/EC_number="3.5.1.5"
/note="ureases catalyze the hydrolysis of urea into
ammonia and carbon dioxide; in Helicobacter pylori the
ammonia released plays a key role in bacterial survival by
neutralizing acids when colonizing the gastric mucosa; the
holoenzyme is composed of 3 ureC (alpha) and 3 ureAB
(gamma/beta) subunits"
/codon_start=1
/transl_table=11
/product="urease subunit alpha"
/protein_id="YP_001289940.1"
/db_xref="GI:148825187"
/db_xref="GeneID:5225431"
/translation="MALTISRAQYVATYGPTVGDKVRLGDTNLWATIEQDLLTKGDEC
KFGGGKSVRDGMAQSGTATRDNPNVLDFVITNVMIIDAKLGIIKADIGIRDGRIVGIG
QAGNPDTMDNVTPNMIIGASTEVHNGAHLIATAGGIDTHIHFICPQQAQHAIESGVTT
LIGGGTGPADGTHATTCTPGAWYMERMFQAAEALPVNVGFFGKGNCSTLDPLREQIEA
GALGLKIHEDWGATPAVIDSALKVADEMDIQVAIHTDTLNESGFLEDTMKAIDGRVIH
TFHTEGAGGGHAPDIIKAAMYSNVLPASTNPTRPFTKNTIDEHLDMLMVCHHLDKRVP
EDVAFADSRIRPETIAAEDILHDMGVFSIMSSDSQAMGRIGEVVIRTWQTADKMKMQR
GELGNEGNDNFRIKRYIAKYTINPAIAHGIAEHIGSLEVGKIADIVLWKPMFFGVKPE
VVIKKGFISYAKMGDPNASIPTPQPVFYRPMYGAQGLATAQTAVFFVSQAAEKADIRE
KFGLHKETIAVKGCRNVGKKDLVHNDVTPNITVDAERYEVRVDGELITCEPVDSVPLG
QRYFLF"
misc_feature 52612..54318
/gene="ureC"
/locus_tag="CGSHiEE_00295"
/note="urease subunit alpha; Reviewed; Region: ureC;
PRK13207"
/db_xref="CDD:183894"
misc_feature 52612..54315
/gene="ureC"
/locus_tag="CGSHiEE_00295"
/note="Urease alpha-subunit; Urease is a nickel-dependent
metalloenzyme that catalyzes the hydrolysis of urea to
form ammonia and carbon dioxide. Nickel-dependent ureases
are found in bacteria, fungi and plants. Their primary
role is to allow the use of...; Region: Urease_alpha;
cd00375"
/db_xref="CDD:30031"
misc_feature order(52612..52617,52621..52623,52642..52644,52660..52665,
52669..52671,52675..52677,52720..52731,52735..52737,
52753..52755,52762..52770,52921..52935,52990..52992,
53929..53931,53995..54012,54016..54024,54037..54039,
54301..54315)
/gene="ureC"
/locus_tag="CGSHiEE_00295"
/note="subunit interactions [polypeptide binding]; other
site"
/db_xref="CDD:30031"
misc_feature order(53023..53025,53029..53031,53122..53124,53272..53274,
53278..53280,53359..53361,53437..53439,53452..53454,
53581..53583,53701..53703,53710..53715)
/gene="ureC"
/locus_tag="CGSHiEE_00295"
/note="active site"
/db_xref="CDD:30031"
misc_feature 53566..53616
/gene="ureC"
/locus_tag="CGSHiEE_00295"
/note="flap region; other site"
/db_xref="CDD:30031"
gene 54449..55006
/gene="ureE"
/locus_tag="CGSHiEE_00300"
/db_xref="GeneID:5225432"
CDS 54449..55006
/gene="ureE"
/locus_tag="CGSHiEE_00300"
/note="involved in the assembly of the urease
metallocenter; possible nickel donor"
/codon_start=1
/transl_table=11
/product="urease accessory protein UreE"
/protein_id="YP_001289941.1"
/db_xref="GI:148825188"
/db_xref="GeneID:5225432"
/translation="MKIINPILPIIENILGNLTALQAEGKITTQPIERVALQWYESER
NILRKTTNTGREVAFRLLKEGQRLKHDDVVFISDELVIAIEILPSDVIVLSPKTLPEM
ARACYEIGNKHSPLFLDGDEVILPYDKPMFEWLQAAGFHPQKAERRLSQALRANSAQG
HGHSHSHSHDHHGYHHHGDGHWHKH"
misc_feature 54494..54922
/gene="ureE"
/locus_tag="CGSHiEE_00300"
/note="urease accessory protein UreE; Provisional; Region:
ureE; PRK13261"
/db_xref="CDD:183927"
misc_feature 54515..54895
/gene="ureE"
/locus_tag="CGSHiEE_00300"
/note="UreE urease accessory protein. UreE is a
metallochaperone assisting the insertion of a Ni2+ ion in
the active site of urease, an important step in the in
vivo assembly of urease, an enzyme that hydrolyses urea
into ammonia and carbamic acid. The...; Region: UreE;
cd00571"
/db_xref="CDD:29664"
misc_feature order(54764..54772,54776..54781,54785..54790,54806..54808)
/gene="ureE"
/locus_tag="CGSHiEE_00300"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:29664"
misc_feature order(54785..54787,54830..54832)
/gene="ureE"
/locus_tag="CGSHiEE_00300"
/note="catalytic residues [active]"
/db_xref="CDD:29664"
gene 54991..55698
/locus_tag="CGSHiEE_00305"
/db_xref="GeneID:5225083"
CDS 54991..55698
/locus_tag="CGSHiEE_00305"
/note="COG0830 Urease accessory protein UreF"
/codon_start=1
/transl_table=11
/product="urease accessory protein UreF"
/protein_id="YP_001289942.1"
/db_xref="GI:148825189"
/db_xref="GeneID:5225083"
/translation="MAQTLNRSLTDLGALLHLVDPTLPIGGFNHSNGLETFVQQRVVE
SKATLEEYVQTQLLQNWIYNDGAYLSLAFDAMNEGNFDRLCELDWQLSATKVARESRE
GSFKLGVRLLKIFIRYETHTLLTAYQQAIAEKRVQGYFPIVFAMVAQAMGLTKADTLY
AFYYNAAVGAITNGVKLIPLSQMDGQDILFDLRGSLVQAVELSLDPDEEWLGAATLAN
DIRAMQHEVLYTRLYMS"
misc_feature 55006..55695
/locus_tag="CGSHiEE_00305"
/note="Urease accessory protein UreF [Posttranslational
modification, protein turnover, chaperones]; Region: UreF;
COG0830"
/db_xref="CDD:31172"
misc_feature 55117..55569
/locus_tag="CGSHiEE_00305"
/note="UreF; Region: UreF; pfam01730"
/db_xref="CDD:201941"
gene 55843..56478
/locus_tag="CGSHiEE_00310"
/db_xref="GeneID:5225084"
CDS 55843..56478
/locus_tag="CGSHiEE_00310"
/note="COG0378 Ni2+-binding GTPase involved in regulation
of expression and maturation of urease and hydrogenase"
/codon_start=1
/transl_table=11
/product="urease accessory protein"
/protein_id="YP_001289943.1"
/db_xref="GI:148825190"
/db_xref="GeneID:5225084"
/translation="MRNYIKIGVAGPVGAGKTALIEKLTREIASKYSVAVITNDIYTQ
EDAEFLTKNSLLPPERIMGVETGGCPHTAIREDASMNLEAVDEMVARFPDVEIVFIES
GGDNLSATFSPDLADVTIFVIDVAQGEKIPRKGGPGITRSDLLVINKTDLAPFVGADL
SVMERDACRMRNGQPFIFTNLMKKENLDGVIGWIEKYALLKNVEEPASLIR"
misc_feature 55864..56406
/locus_tag="CGSHiEE_00310"
/note="Rat sarcoma (Ras)-like superfamily of small
guanosine triphosphatases (GTPases); Region:
Ras_like_GTPase; cd00882"
/db_xref="CDD:206648"
misc_feature 55873..55896
/locus_tag="CGSHiEE_00310"
/note="G1 box; other site"
/db_xref="CDD:206648"
misc_feature order(55879..55899,56044..56046,56284..56289,56293..56295,
56380..56388)
/locus_tag="CGSHiEE_00310"
/note="GTP/Mg2+ binding site [chemical binding]; other
site"
/db_xref="CDD:206648"
misc_feature 55969..55971
/locus_tag="CGSHiEE_00310"
/note="G2 box; other site"
/db_xref="CDD:206648"
misc_feature 55984..55992
/locus_tag="CGSHiEE_00310"
/note="Switch I region; other site"
/db_xref="CDD:206648"
misc_feature 56035..56046
/locus_tag="CGSHiEE_00310"
/note="G3 box; other site"
/db_xref="CDD:206648"
misc_feature order(56041..56046,56122..56127)
/locus_tag="CGSHiEE_00310"
/note="Switch II region; other site"
/db_xref="CDD:206648"
misc_feature 56284..56295
/locus_tag="CGSHiEE_00310"
/note="G4 box; other site"
/db_xref="CDD:206648"
misc_feature 56380..56388
/locus_tag="CGSHiEE_00310"
/note="G5 box; other site"
/db_xref="CDD:206648"
gene 56551..57366
/gene="groES"
/locus_tag="CGSHiEE_00315"
/db_xref="GeneID:5225085"
CDS 56551..57366
/gene="groES"
/locus_tag="CGSHiEE_00315"
/note="COG0829 Urease accessory protein UreH"
/codon_start=1
/transl_table=11
/product="co-chaperonin GroES"
/protein_id="YP_001289944.1"
/db_xref="GI:148825191"
/db_xref="GeneID:5225085"
/translation="MNSKLSLSTKLSSSGKTQLAEYFAKPPFKVITLPSYDDAWANGL
NAMQMSSSPGVLAGDVLEIDISLAKLTALSLNTQAFTRVQAMNEGDSAMQTTHILLAE
NSRLFYLPHPLVLHKDSVFKQQTHIEMGEQSELIYGEIVAIGRVLNDERFAFRQFSSH
LKIYTLQDDGKKRPLVSDCIQWLPSKMNLTALSQMENYSHQGSLTYLNLAKNNAEIKQ
QVQALQQQSAEEKDLLIGISQLNEYGLMVRVLGCRAEQIQKLFEKIGRLLKSV"
misc_feature 56602..57360
/gene="groES"
/locus_tag="CGSHiEE_00315"
/note="Urease accessory protein UreH [Posttranslational
modification, protein turnover, chaperones]; Region: UreH;
COG0829"
/db_xref="CDD:31171"
gene 57522..58940
/gene="aspA"
/locus_tag="CGSHiEE_00320"
/db_xref="GeneID:5225086"
CDS 57522..58940
/gene="aspA"
/locus_tag="CGSHiEE_00320"
/EC_number="4.3.1.1"
/note="catalyzes the formation of fumarate from aspartate"
/codon_start=1
/transl_table=11
/product="aspartate ammonia-lyase"
/protein_id="YP_001289945.1"
/db_xref="GI:148825192"
/db_xref="GeneID:5225086"
/translation="MTQFRKEVDLLGERDVPAEEYWGIHTLRAVENFNISNVTISDVP
EFVRGMVMVKKATALANGELGAIPSDIAKAIVAACDEILTTGKCLDQFPSDVYQGGAG
TSVNMNTNEVVANLALEKIGHKKGEYNVINPMDHVNASQSTNDAYPTGFRIAVYNSIL
KLIDKIQYLHDGFDNKAKEFANILKMGRTQLQDAVPMTVGQEFKAFAVLLEEEVRNLK
RTAGLLLEINLGATAIGTGLNTPQGYTELVVKHLAEVTGLACVPAENLIEATSDCGAY
VMVHGALKRTAVKLSKVCNDLRLLSSGPRAGLKEINLPELQAGSSIMPAKVNPVVPEV
VNQVCFKVIGNDTTVTFASEAGQLQLNVMEPVIGQAMFESIDILTNACVNLRDKCVDG
ITVNKEICENYVFNSIGIVTYLNPFIGHHNGDLVGKICAQTGKGVREVVLEKGLLTEE
QLDDILSVENLMNPTYKAKLNK"
misc_feature 57522..58931
/gene="aspA"
/locus_tag="CGSHiEE_00320"
/note="aspartate ammonia-lyase; Provisional; Region: aspA;
PRK12273"
/db_xref="CDD:183393"
misc_feature 57534..58892
/gene="aspA"
/locus_tag="CGSHiEE_00320"
/note="Aspartase; Region: Aspartase; cd01357"
/db_xref="CDD:176462"
misc_feature order(57819..57830,57945..57953,58086..58091,58497..58499,
58503..58505,58518..58520)
/gene="aspA"
/locus_tag="CGSHiEE_00320"
/note="active sites [active]"
/db_xref="CDD:176462"
misc_feature order(58083..58094,58104..58106,58122..58127,58143..58145,
58155..58157,58167..58169,58221..58223,58311..58316,
58323..58325,58332..58337,58341..58343,58350..58355,
58362..58364,58371..58376,58383..58388,58392..58397,
58404..58409,58557..58559,58581..58583,58590..58598,
58755..58757)
/gene="aspA"
/locus_tag="CGSHiEE_00320"
/note="tetramer interface [polypeptide binding]; other
site"
/db_xref="CDD:176462"
gene complement(59244..61181)
/gene="aspA"
/locus_tag="CGSHiEE_00325"
/db_xref="GeneID:5225087"
CDS complement(59244..61181)
/gene="aspA"
/locus_tag="CGSHiEE_00325"
/EC_number="4.3.1.1"
/note="COG0568 DNA-directed RNA polymerase, sigma subunit
(sigma70/sigma32)"
/codon_start=1
/transl_table=11
/product="aspartate ammonia-lyase"
/protein_id="YP_001289946.1"
/db_xref="GI:148825193"
/db_xref="GeneID:5225087"
/translation="MVESRVHKKSYLLNHIKQNEYKNGKNQQSTAEQYSEQIEQLMEL
GRTQGYLTFAEINDLLPEDAIDPEYYDKLLQTLQNDAGIPVLDEAPESDDMMLSDTIP
DEDAVEEATQILSNVESEIGRTTDPVRMYMREMGTVDLLTREDEISIAKRIEGGIDEV
QTSIAAYPEALNGLLKNYDDVEKGNFRLTDLITGFVDPNAEIEEHNGLDEDFSDEDDE
EESSNADVEDNESESTSDSSDSDNSIDPEVAREKFQQLREQHSKTLAVIEKHGRSGKR
AQDQIALLGEIFKQFRLVPKQFDLLVLSMKEMMKRVRYQERQLQKILVDIAGMPKDDF
EKIITTNGSNSEWVAKALKSSKPWAKRLIKYEDRIYEALNNLAITEENTKLTITQMRD
ICDAVARGEQKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDK
FEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQLLQEMGR
EATPEELAERMGMPEDKIRKVLKIAKEPISMETPIGDDDDSHLGDFIEDSTLELPLDS
ATAQSLKVATHEVLEGLTPREAKVLRMRFGIDMNTDHTLEEVGKQFDVTRERIRQIEA
KALRKLRHPSRSETLRSFLDE"
misc_feature complement(59247..61100)
/gene="aspA"
/locus_tag="CGSHiEE_00325"
/note="RNA polymerase sigma factor RpoD; Validated;
Region: PRK05658"
/db_xref="CDD:180186"
misc_feature complement(60849..61094)
/gene="aspA"
/locus_tag="CGSHiEE_00325"
/note="Sigma-70 factor, region 1.1; Region: Sigma70_r1_1;
pfam03979"
/db_xref="CDD:112778"
misc_feature complement(60714..60809)
/gene="aspA"
/locus_tag="CGSHiEE_00325"
/note="Sigma-70 factor, region 1.2; Region: Sigma70_r1_2;
pfam00140"
/db_xref="CDD:201030"
misc_feature complement(60042..60683)
/gene="aspA"
/locus_tag="CGSHiEE_00325"
/note="Sigma-70, non-essential region; Region:
Sigma70_ner; pfam04546"
/db_xref="CDD:203043"
misc_feature complement(59739..59951)
/gene="aspA"
/locus_tag="CGSHiEE_00325"
/note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542"
/db_xref="CDD:146937"
misc_feature complement(59481..59714)
/gene="aspA"
/locus_tag="CGSHiEE_00325"
/note="Sigma-70 region 3; Region: Sigma70_r3; pfam04539"
/db_xref="CDD:146934"
misc_feature complement(59289..59465)
/gene="aspA"
/locus_tag="CGSHiEE_00325"
/note="Sigma70, region (SR) 4 refers to the most
C-terminal of four conserved domains found in Escherichia
coli (Ec) sigma70, the main housekeeping sigma, and
related sigma-factors (SFs). A SF is a dissociable subunit
of RNA polymerase, it directs bacterial or...; Region:
Sigma70_r4; cd06171"
/db_xref="CDD:100119"
misc_feature complement(order(59301..59303,59307..59312,59316..59324,
59328..59333,59337..59339,59367..59372,59400..59402,
59430..59432))
/gene="aspA"
/locus_tag="CGSHiEE_00325"
/note="DNA binding residues [nucleotide binding]"
/db_xref="CDD:100119"
gene complement(61184..62965)
/gene="dnaG"
/locus_tag="CGSHiEE_00330"
/db_xref="GeneID:5225056"
CDS complement(61184..62965)
/gene="dnaG"
/locus_tag="CGSHiEE_00330"
/note="synthesizes RNA primers at the replication forks"
/codon_start=1
/transl_table=11
/product="DNA primase"
/protein_id="YP_001289947.1"
/db_xref="GI:148825194"
/db_xref="GeneID:5225056"
/translation="MKGSIPRPFIDDLLTKSDIVDVINTRVKLKKAGRDYQACCPFHH
EKTPSFTVSQKKQFYHCFGCGAHGNAISFLMDYDKLEFIEAIEELAAMAGLEIPYEKR
ANHSGKPQANYQTKRNLYELMQEIATFYQNQLPLNTQAQEYLQQRGLSPEIIERFQIG
FVPNAMDTVLRKFGVNREEQQKLIELGMLSRNDRGNIYDKFRNRIMFPIRDKRGRTVA
FGGRVLTDEKPKYLNSPETITYHKGKELYGLYEALQTNDEPKQLLVVEGYMDVVALAQ
FGVDYAVASLGTSTTSEQIQLIFRSTEQVVCCYDGDRAGRDAAWRALENALPYLEDGR
QLKFIFLPDGEDPDTYIRQYGKEKFEEYIESAQSLSEFMFAHLSPQVDFSTKEGRGKL
VALAAPLIHQIPGEMLRLSLRNMLAQKLGIFDQTQLENLIPKQLEQANTQQKVTHNKI
KKTPMRMVISLLLQNPELVKRMSESGVQALRAEAGFEILEKLTALCRQREGITTGQIL
EYFRNTSYSNPLEILATWDHLLDESDIINAFSQNYRRLNIQAIERDIEMLIAKERTEG
LTNEEKTVLVHLLAGKEQQKKQLVNPL"
misc_feature complement(61202..62959)
/gene="dnaG"
/locus_tag="CGSHiEE_00330"
/note="DNA primase; Validated; Region: dnaG; PRK05667"
/db_xref="CDD:180189"
misc_feature complement(<62729..62953)
/gene="dnaG"
/locus_tag="CGSHiEE_00330"
/note="CHC2 zinc finger; Region: zf-CHC2; pfam01807"
/db_xref="CDD:110780"
misc_feature complement(62207..62581)
/gene="dnaG"
/locus_tag="CGSHiEE_00330"
/note="DNA primase catalytic core, N-terminal domain;
Region: Toprim_N; pfam08275"
/db_xref="CDD:203896"
misc_feature complement(61943..62188)
/gene="dnaG"
/locus_tag="CGSHiEE_00330"
/note="TOPRIM_DnaG_primases: The topoisomerase-primase
(TORPIM) nucleotidyl transferase/hydrolase domain found in
the active site regions of proteins similar to Escherichia
coli DnaG. Primases synthesize RNA primers for the
initiation of DNA replication. DnaG...; Region:
TOPRIM_DnaG_primases; cd03364"
/db_xref="CDD:173784"
misc_feature complement(order(62024..62026,62030..62032,62036..62038,
62156..62158,62165..62170))
/gene="dnaG"
/locus_tag="CGSHiEE_00330"
/note="active site"
/db_xref="CDD:173784"
misc_feature complement(order(62036..62038,62168..62170))
/gene="dnaG"
/locus_tag="CGSHiEE_00330"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:173784"
misc_feature complement(order(62108..62110,62138..62143,62159..62164))
/gene="dnaG"
/locus_tag="CGSHiEE_00330"
/note="interdomain interaction site; other site"
/db_xref="CDD:173784"
misc_feature complement(61685..61861)
/gene="dnaG"
/locus_tag="CGSHiEE_00330"
/note="DnaB-helicase binding domain of primase; Region:
DnaB_bind; pfam10410"
/db_xref="CDD:204477"
misc_feature complement(61229..61603)
/gene="dnaG"
/locus_tag="CGSHiEE_00330"
/note="DNA primase DnaG DnaB-binding; Region:
DnaG_DnaB_bind; smart00766"
/db_xref="CDD:197866"
gene complement(63099..63314)
/gene="rpsU"
/locus_tag="CGSHiEE_00335"
/db_xref="GeneID:5225057"
CDS complement(63099..63314)
/gene="rpsU"
/locus_tag="CGSHiEE_00335"
/note="a small basic protein that is one of the last in
the subunit assembly; omission does not prevent assembly
but the subunit is inactive; binds central domain of 16S
rRNA"
/codon_start=1
/transl_table=11
/product="30S ribosomal protein S21"
/protein_id="YP_001289948.1"
/db_xref="GI:148825195"
/db_xref="GeneID:5225057"
/translation="MPVIKVRENESFDVALRRFKRSCEKAGILAEVRAREFYEKPTTI
RKRENATLAKRHAKRNARENARNTRLY"
misc_feature complement(63123..63314)
/gene="rpsU"
/locus_tag="CGSHiEE_00335"
/note="30S ribosomal protein S21; Reviewed; Region: rpsU;
PRK00270"
/db_xref="CDD:178952"
gene 63546..64574
/locus_tag="CGSHiEE_00340"
/gene_synonym="gcp"
/db_xref="GeneID:5225058"
CDS 63546..64574
/locus_tag="CGSHiEE_00340"
/gene_synonym="gcp"
/note="in most organisms, only the N-terminal domain is
present in a single polypeptide; in some archaea this
domain is fused to a kinase domain; this gene is essential
for growth in Escherichia coli and Bacillus subtilis; the
secreted glycoprotease from Pasteurella haemolytica showed
specificity for O-sialoglycosylated proteins; the
Pyrococcus structure shows DNA-binding properties,
iron-binding, ATP-binding, and AP endonuclease activity"
/codon_start=1
/transl_table=11
/product="putative DNA-binding/iron metalloprotein/AP
endonuclease"
/protein_id="YP_001289949.1"
/db_xref="GI:148825196"
/db_xref="GeneID:5225058"
/translation="MKILGIETSCDETGVAIYDEEKGLIANQLYTQIALHADYGGVVP
ELASRDHIRKTAPLIKAALEEAKLTASDIDGVAYTSGPGLVGALLVGATIARSLAYAW
NVPAIGVHHMEGHLLAPMLDENSPHFPFVALLVSGGHTQLVRVDGVGKYEVIGESIDD
AAGEAFDKTAKLLGLDYPGGAALSRLAEKGTPNRFIFPRPMTDRAGLDFSFSGLKTFA
ANTVNQAIKNEGELTEQTKVDIAYAFQDAVVDTLAIKCKRALKETGYKRLVIAGGVSA
NKKLRETLAHLMQNLGGEVFYPQPQFCTDNGAMIAYTGLLRLKQGQHSDLAIDVKPRW
AMTELLAI"
misc_feature 63546..64571
/locus_tag="CGSHiEE_00340"
/gene_synonym="gcp"
/note="UGMP family protein; Validated; Region: PRK09604"
/db_xref="CDD:181984"
misc_feature 63552..>63872
/locus_tag="CGSHiEE_00340"
/gene_synonym="gcp"
/note="universal bacterial protein YeaZ; Region:
bact_YeaZ; TIGR03725"
/db_xref="CDD:211869"
gene 64583..65164
/locus_tag="CGSHiEE_00345"
/db_xref="GeneID:5225059"
CDS 64583..65164
/locus_tag="CGSHiEE_00345"
/EC_number="2.7.1.21"
/note="catalyzes the formation of thymidine 5'-phosphate
from thymidine"
/codon_start=1
/transl_table=11
/product="thymidine kinase"
/protein_id="YP_001289950.1"
/db_xref="GI:148825197"
/db_xref="GeneID:5225059"
/translation="MAKLYFYYSTMNAGKSTTLLQSSYNYRERDMNTLVYTAAIDDRF
GVGKVTSRIGISQDAFLFRSETNLFDEINEHLKKEKVHCVLVDEAQFLSKQQVYQLSD
VVDKLKIPVLCYGLRTDFQAELFEGSKYLLAWADQLEELKTICYCGRKANFVLRLNDQ
GEVIKEGAQIQIGGNDSYLSVCRLHYKEKCGQI"
misc_feature 64583..65146
/locus_tag="CGSHiEE_00345"
/note="thymidine kinase; Provisional; Region: PRK04296"
/db_xref="CDD:179813"
misc_feature <64622..>64852
/locus_tag="CGSHiEE_00345"
/note="P-loop containing Nucleoside Triphosphate
Hydrolases; Region: P-loop_NTPase; cl09099"
/db_xref="CDD:213113"
misc_feature order(64622..64630,64688..64690,64694..64699,64841..64846)
/locus_tag="CGSHiEE_00345"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:29986"
misc_feature 64622..64630
/locus_tag="CGSHiEE_00345"
/note="Walker A motif; other site"
/db_xref="CDD:29986"
misc_feature 64829..64843
/locus_tag="CGSHiEE_00345"
/note="Walker B motif; other site"
/db_xref="CDD:29986"
gene 65201..66421
/locus_tag="CGSHiEE_00350"
/db_xref="GeneID:5225060"
CDS 65201..66421
/locus_tag="CGSHiEE_00350"
/note="COG0814 Amino acid permeases"
/codon_start=1
/transl_table=11
/product="tyrosine-specific transport protein 2"
/protein_id="YP_001289951.1"
/db_xref="GI:148825198"
/db_xref="GeneID:5225060"
/translation="MLKNKTFGSALIIAGTTIGAGMLAMPLTSAGMGFGYTLLLLVGL
WALLVYSGLLFVEVYQTADQLDDGVATLAEKYFGAPGRILATLSLLVLLYALSAAYIT
GGGSLLSGLPTAFGMDAISLKTAIIIFTVVLGSFVVVGTKGVDGLTRVLFIGKLVAFA
FVLFMMLPKVATDNLMALPLDYAFVVSAAPIFFTSFGFHVIMASVNSYLGGSVDKFRR
AILIGTAIPLAAYLVWQLATHGVLSQSEFVRILQADPTLNGLVNATREITSSHFMGEV
VRAFSSLALITSFLGVMLGVFEGLGDLFKRYHLPNNRFVLTVVAFLPPLVFALFYPEG
FITALSYAGLLCAFYCLILPIGLAWRTRIENPTLPYRVSGGNFALVFALLIGVVIMLI
PFLIQWGYLPVVAG"
misc_feature 65207..66379
/locus_tag="CGSHiEE_00350"
/note="Tryptophan/tyrosine permease family; Region:
Trp_Tyr_perm; pfam03222"
/db_xref="CDD:112053"
misc_feature 65222..66358
/locus_tag="CGSHiEE_00350"
/note="aromatic amino acid transport protein; Region:
araaP; TIGR00837"
/db_xref="CDD:162061"
gene complement(66559..66819)
/locus_tag="CGSHiEE_00355"
/db_xref="GeneID:5225061"
CDS complement(66559..66819)
/locus_tag="CGSHiEE_00355"
/note="COG1145 Ferredoxin"
/codon_start=1
/transl_table=11
/product="putative ferredoxin-like protein"
/protein_id="YP_001289952.1"
/db_xref="GI:148825199"
/db_xref="GeneID:5225061"
/translation="MALFITSKCTNCDMCLPECPNEAISIGDEIYVIDPILCTECVGH
YDTPTCQKVCPITNCIKPDPEHQETEEQLWERFVMIHHSDKL"
misc_feature complement(66655..66795)
/locus_tag="CGSHiEE_00355"
/note="4Fe-4S dicluster domain; Region: Fer4_7; pfam12838"
/db_xref="CDD:205099"
gene 67132..67680
/locus_tag="CGSHiEE_00360"
/db_xref="GeneID:5225021"
CDS 67132..67680
/locus_tag="CGSHiEE_00360"
/EC_number="2.7.1.21"
/note="COG3719 Ribonuclease I"
/codon_start=1
/transl_table=11
/product="thymidine kinase"
/protein_id="YP_001289953.1"
/db_xref="GI:148825200"
/db_xref="GeneID:5225021"
/translation="MRNDHIGQNAKAPVDYYMLALSWSPGFCDIQREKYGDQLPYSSQ
YQCGNNRTFGWVVHGLWPQNANARAVSDHPRFCKGDLPALPKGLLAQYLAISPGEKLL
QGEWEKHGSCAFDSAQQYFAKEQELFNALKLPNQKLSRDELFGWMKQHNPQLKNAYLR
ASRNELFICYDKKWQVMNCQSK"
misc_feature 67174..67668
/locus_tag="CGSHiEE_00360"
/note="Ribonuclease T2 (RNase T2) is a widespread family
of secreted RNases found in every organism examined thus
far. This family includes RNase Rh, RNase MC1, RNase LE,
and self-incompatibility RNases (S-RNases). Plant T2
RNases are expressed during leaf...; Region:
RNase_T2_prok; cd01062"
/db_xref="CDD:29474"
misc_feature order(67183..67185,67312..67314,67630..67632)
/locus_tag="CGSHiEE_00360"
/note="B1 nucleotide binding pocket [chemical binding];
other site"
/db_xref="CDD:29474"
misc_feature order(67195..67197,67210..67212,67432..67434,67624..67626)
/locus_tag="CGSHiEE_00360"
/note="B2 nucleotide binding pocket [chemical binding];
other site"
/db_xref="CDD:29474"
misc_feature order(67294..67317,67432..67467)
/locus_tag="CGSHiEE_00360"
/note="CAS motifs; other site"
/db_xref="CDD:29474"
misc_feature order(67303..67305,67312..67314,67318..67320,67441..67446,
67453..67458)
/locus_tag="CGSHiEE_00360"
/note="active site"
/db_xref="CDD:29474"
gene 67776..68936
/gene="pgk"
/locus_tag="CGSHiEE_00365"
/db_xref="GeneID:5225022"
CDS 67776..68936
/gene="pgk"
/locus_tag="CGSHiEE_00365"
/EC_number="2.7.2.3"
/note="Converts 3-phospho-D-glycerate to
3-phospho-D-glyceroyl phosphate during the glycolysis
pathway"
/codon_start=1
/transl_table=11
/product="phosphoglycerate kinase"
/protein_id="YP_001289954.1"
/db_xref="GI:148825201"
/db_xref="GeneID:5225022"
/translation="MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRATIPTL
KLALEKGAKVMVTSHLGRPTEGEFKPEDSLQPVVDYLKNAGFNVRLEQDYLNGVDVKD
GEIVVLENVRVNKGEKKNDPELGKKYAALCDVFVMDAFGTAHRAQASTYGVAEFAPIA
CAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLEVLNSLSKIADQIIVGGGIAN
TFIAAAGHNVGKSLYEADLIPVAKELAANTDIPVPVDVRVGLEFSETAAATEKAVNEV
KDDESIFDIGDKSAEQLAEIIKNAKTVLWNGPVGVFEFPHFRKGTEIISHAIANSDAF
SIAGGGDTLAAINLFGIADKISYISTGGGAFLEFVEGKVLPAVEILEKRAKN"
misc_feature 67791..68918
/gene="pgk"
/locus_tag="CGSHiEE_00365"
/note="Phosphoglycerate kinase (PGK) is a monomeric enzyme
which catalyzes the transfer of the high-energy phosphate
group of 1,3-bisphosphoglycerate to ADP, forming ATP and
3-phosphoglycerate. This reaction represents the first of
the two substrate-level...; Region:
Phosphoglycerate_kinase; cd00318"
/db_xref="CDD:29400"
misc_feature 67791..68891
/gene="pgk"
/locus_tag="CGSHiEE_00365"
/note="Phosphoglycerate kinase; Region: PGK; pfam00162"
/db_xref="CDD:201047"
misc_feature order(67836..67838,67842..67844,67881..67883,67950..67952,
68109..68111)
/gene="pgk"
/locus_tag="CGSHiEE_00365"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:29400"
misc_feature order(68304..68315,68847..68855)
/gene="pgk"
/locus_tag="CGSHiEE_00365"
/note="hinge regions; other site"
/db_xref="CDD:29400"
misc_feature order(68418..68420,68619..68621,68691..68693,68697..68699,
68703..68714,68793..68801)
/gene="pgk"
/locus_tag="CGSHiEE_00365"
/note="ADP binding site [chemical binding]; other site"
/db_xref="CDD:29400"
misc_feature 68796..68798
/gene="pgk"
/locus_tag="CGSHiEE_00365"
/note="catalytic site [active]"
/db_xref="CDD:29400"
gene 69047..70126
/locus_tag="CGSHiEE_00370"
/db_xref="GeneID:5225023"
CDS 69047..70126
/locus_tag="CGSHiEE_00370"
/EC_number="4.1.2.13"
/note="catalyzes the formation of glycerone phosphate and
glyceraldehyde 3-phosphate from fructose 1,6,
bisphosphate"
/codon_start=1
/transl_table=11
/product="fructose-bisphosphate aldolase"
/protein_id="YP_001289955.1"
/db_xref="GI:148825202"
/db_xref="GeneID:5225023"
/translation="MAKLLDIVKPGVITGEDVQKVFAYAKEHNFAIPAVNCVGSDSVN
AVLETAARVKAPVIIQFSNGGAAFYAGKGIKPTSGTRPDVLGAIAGAKQVHTLAKEYG
VPVILHTDHAAKKLLPWIDGLLDAGEKHFAETGRPLFSSHMIDLSEEPMEENMAICRE
YLARMDKMGMTLEIEIGITGGEEDGVDNSDVDESRLYTQPSDVLYVYDQLHPVSPNFT
VAAAFGNVHGVYKPGNVKLKPSILGASQEFVSKERNLPAKPINFVFHGGSGSSREEIR
EAIGYGAIKMNIDTDTQWASWNGILNFYKANEAYLQGQLGNPEGPDAPNKKYYDPRVW
LRKMEESMSKRLEQSFEDLNCVDVL"
misc_feature 69074..70123
/locus_tag="CGSHiEE_00370"
/note="fructose-bisphosphate aldolase; Provisional;
Region: PRK09197"
/db_xref="CDD:181692"
misc_feature 69089..70123
/locus_tag="CGSHiEE_00370"
/note="Class II Type A, Fructose-1,6-bisphosphate (FBP)
aldolases. The enzyme catalyses the zinc-dependent,
reversible aldol condensation of dihydroxyacetone
phosphate with glyceraldehyde-3-phosphate to form
fructose-1,6-bisphosphate. FBP aldolase is...; Region:
FBP_aldolase_IIA; cd00946"
/db_xref="CDD:29572"
misc_feature order(69152..69154,69374..69379,69479..69481,69569..69571,
69575..69577,69584..69595,69722..69730,69734..69736,
69839..69844,69848..69850,69905..69907,69911..69916)
/locus_tag="CGSHiEE_00370"
/note="active site"
/db_xref="CDD:29572"
misc_feature order(69161..69169,69176..69178,69239..69241,69248..69256,
69311..69313,69323..69325,69332..69337,69593..69595,
69914..69919,69923..69928,69935..69937,69947..69949,
69956..69958)
/locus_tag="CGSHiEE_00370"
/note="intersubunit interface [polypeptide binding]; other
site"
/db_xref="CDD:29572"
misc_feature order(69377..69379,69479..69481,69569..69571,69590..69592,
69725..69727,69839..69841)
/locus_tag="CGSHiEE_00370"
/note="zinc binding site [ion binding]; other site"
/db_xref="CDD:29572"
misc_feature order(69722..69724,69728..69730,69734..69736,69842..69844,
69848..69850)
/locus_tag="CGSHiEE_00370"
/note="Na+ binding site [ion binding]; other site"
/db_xref="CDD:29572"
misc_feature 70195..71236
/note="potential frameshift: common BLAST hit:
gi|68249120|ref|YP_248232.1|
ADP-heptose--lipooligosaccharide heptosyltransferase III"
misc_feature complement(71192..71850)
/note="potential frameshift: common BLAST hit:
gi|68249119|ref|YP_248231.1| predicted membrane protein
[Haemophilus influenzae 86-028NP]"
gene 72066..73610
/locus_tag="CGSHiEE_00395"
/db_xref="GeneID:5225024"
CDS 72066..73610
/locus_tag="CGSHiEE_00395"
/note="COG1882 Pyruvate-formate lyase"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289956.1"
/db_xref="GI:148825203"
/db_xref="GeneID:5225024"
/translation="MLASLQDILDTVKANNLTYHQKLMTLGNIAERLFDPRNLLGYTD
EEWGFLQNQMICDLCEGYAIYRPRYILPDYNVYIQKGCEFLELPPPKDLDEALDGLLI
LYSHVPSITTYPVYIGRLDVLLEPFITDEEKDYIKIKRFLNHIDKTVPDSFCHANIGP
YDTKAGRLILRAVIELEAPTPNMTIRYDKSKTSREFAELAAKACLLVSKPSFANDAYY
ISDLGEEYGVASCYNALPECGGAYTLTRLRLGTIARACKSADEMVNELLPRVAKCALS
TMDKRHKFVVEESNFFNSSFLEKEGFIKRTNFTGMFAIVGLADATNHLLQCEGLNETF
GKSVRGDEIATAIMDKLKKITDAHEGVYAERTGNRYLLHAQVGASNHEEDKRNAPAHR
IRVGEEPTLLAHLKQSAPFHKYFPSGTGDLFAFDQTYVDHCDAVVDIIDGAFSLGYRY
ITTYLKNTDLIRVTGYLVKKSEVEKYRKGEVALRDTTWYGSGTDECANVFDRQLRNEK
DVIAEK"
misc_feature 72081..73580
/locus_tag="CGSHiEE_00395"
/note="glycine radical enzyme, YjjI family; Region:
glycyl_YjjI; TIGR04040"
/db_xref="CDD:188555"
misc_feature 72111..73580
/locus_tag="CGSHiEE_00395"
/note="Protein of unknown function (DUF3029); Region:
DUF3029; pfam11230"
/db_xref="CDD:151672"
gene 73619..74407
/locus_tag="CGSHiEE_00400"
/db_xref="GeneID:5225003"
CDS 73619..74407
/locus_tag="CGSHiEE_00400"
/note="COG1180 Pyruvate-formate lyase-activating enzyme"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289957.1"
/db_xref="GI:148825204"
/db_xref="GeneID:5225003"
/translation="MTALSEIFVPLHRIIPFSNVEGQGNRSSIFLQGCKLNCLYCHNP
ETIPRYTENAKLVSLQYLYEQVMEAVPFIRGVTVSGGEPTIHHKKLVPLFKALRSQGL
TCYLDSSGFFEFDRVCSLIDVTDKFLFDLKGEGIGLQTLCFDRKNQAGIVPQQVILER
LHIKNDKLERNLQNLAALLPLNKVEEVRLVFLKHFFDAEHLVGKVAQLLRNYPDVALK
IIRMHSKGVRDEAGLSAHISSVEETNALSAYARQCGINKVLTIL"
misc_feature 73646..74401
/locus_tag="CGSHiEE_00400"
/note="glycine radical enzyme activase, YjjW family;
Region: activase_YjjW; TIGR04041"
/db_xref="CDD:188556"
misc_feature 73703..>73966
/locus_tag="CGSHiEE_00400"
/note="Radical SAM superfamily. Enzymes of this family
generate radicals by combining a 4Fe-4S cluster and
S-adenosylmethionine (SAM) in close proximity. They are
characterized by a conserved CxxxCxxC motif, which
coordinates the conserved iron-sulfur cluster; Region:
Radical_SAM; cd01335"
/db_xref="CDD:100105"
misc_feature order(73718..73720,73724..73726,73730..73732,73736..73744,
73853..73855,73859..73864,73937..73945)
/locus_tag="CGSHiEE_00400"
/note="FeS/SAM binding site; other site"
/db_xref="CDD:100105"
gene 74506..75759
/locus_tag="CGSHiEE_00405"
/db_xref="GeneID:5225004"
CDS 74506..75759
/locus_tag="CGSHiEE_00405"
/note="COG1972 Nucleoside permease"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289958.1"
/db_xref="GI:148825205"
/db_xref="GeneID:5225004"
/translation="MSVLSSILGMVVLIAIAVLLSNNRKAISIRTVVGALAIQVGFAA
LILYVPAGKQALGAAADMVSNVIAYGNDGINFVFGGLADPSKPSGFIFAVKVLPIIVF
FSGLISVLYYLGIMQVVIKVLGGALQKALGTSKAESMSAAANIFVGQTEAPLVVRPYI
KNMTQSELFAIMVGGTASIAGSVMAGYAGMGVPLTYLIAASFMAAPAGLLFAKLMFPQ
TEQFTDKQPEDNDSEKPTNVLEAMAGGASAGMQLALNVGAMLIAFVGLIALINGILSG
VGGWFGYGDLTLQSIFGLIFKPLAYLIGVTDGAEAGIAGQMIGMKLAVNEFVGYLEFA
KYLQPDSAIVLTEKTKAIITFALCGFANFSSIAILIGGLGGMAPSRRSDVARLGIKAV
IAGTLANLMSATIAGLFIGLGAAAL"
misc_feature 74515..75711
/locus_tag="CGSHiEE_00405"
/note="nucleoside transporter; Region: nupC; TIGR00804"
/db_xref="CDD:162048"
misc_feature 74527..74751
/locus_tag="CGSHiEE_00405"
/note="Na+ dependent nucleoside transporter N-terminus;
Region: Nucleos_tra2_N; pfam01773"
/db_xref="CDD:201962"
misc_feature 74782..75078
/locus_tag="CGSHiEE_00405"
/note="Nucleoside recognition; Region: Gate; pfam07670"
/db_xref="CDD:203716"
misc_feature 75091..75711
/locus_tag="CGSHiEE_00405"
/note="Na+ dependent nucleoside transporter C-terminus;
Region: Nucleos_tra2_C; pfam07662"
/db_xref="CDD:203714"
gene 75833..76549
/gene="deoD"
/locus_tag="CGSHiEE_00410"
/db_xref="GeneID:5225005"
CDS 75833..76549
/gene="deoD"
/locus_tag="CGSHiEE_00410"
/EC_number="2.4.2.1"
/note="catalyzes the reversible phosphorolysis of
ribonucleosides and 2'- deoxyribonucleosides to the free
base and (2'-deoxy)ribose-1- phosphate"
/codon_start=1
/transl_table=11
/product="purine nucleoside phosphorylase"
/protein_id="YP_001289959.1"
/db_xref="GI:148825206"
/db_xref="GeneID:5225005"
/translation="MTPHINAPEGAFADVVLMPGDPLRAKYIAETFLQDVVEVTNVRN
MLGFTGTYKGRKISIMGHGMGIPSCSIYAKELITEYGVKKIIRVGSCGSVRMDVKVRD
VIIGLGACTDSKVNRIRFKDNDFAAIADFDMAQAAVQAAKAKGKAVRVGNLFSADLFY
TPDVEMFDVMEKYGILGVEMEAAGIYGVAAEYSAKALTICTVSDHIRTHEQTTAEERQ
LTFNDMIEIALDSVLIGDAQ"
misc_feature 75833..76537
/gene="deoD"
/locus_tag="CGSHiEE_00410"
/note="purine nucleoside phosphorylase; Reviewed; Region:
deoD; PRK05819"
/db_xref="CDD:180275"
misc_feature 75839..76528
/gene="deoD"
/locus_tag="CGSHiEE_00410"
/note="Uridine phosphorylase [Nucleotide transport and
metabolism]; Region: Udp; COG2820"
/db_xref="CDD:32648"
gene 76720..77148
/gene="rplK"
/locus_tag="CGSHiEE_00415"
/db_xref="GeneID:5225006"
CDS 76720..77148
/gene="rplK"
/locus_tag="CGSHiEE_00415"
/note="binds directly to 23S ribosomal RNA"
/codon_start=1
/transl_table=11
/product="50S ribosomal protein L11"
/protein_id="YP_001289960.1"
/db_xref="GI:148825207"
/db_xref="GeneID:5225006"
/translation="MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNA
RTESLEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKVT
LDQVRQIAETKAADMTGATIETKMKSIAGTARSMGLVVEE"
misc_feature 76720..77145
/gene="rplK"
/locus_tag="CGSHiEE_00415"
/note="50S ribosomal protein L11; Validated; Region: rplK;
PRK00140"
/db_xref="CDD:178895"
misc_feature 76744..77139
/gene="rplK"
/locus_tag="CGSHiEE_00415"
/note="Ribosomal protein L11. Ribosomal protein L11,
together with proteins L10 and L7/L12, and 23S rRNA, form
the L7/L12 stalk on the surface of the large subunit of
the ribosome. The homologous eukaryotic cytoplasmic
protein is also called 60S ribosomal...; Region:
Ribosomal_L11; cd00349"
/db_xref="CDD:100101"
misc_feature order(76747..76749,76807..76809,76942..76950,76960..76962,
76981..76983,77056..77058,77071..77079,77089..77091,
77098..77103,77110..77115,77119..77127)
/gene="rplK"
/locus_tag="CGSHiEE_00415"
/note="23S rRNA interface [nucleotide binding]; other
site"
/db_xref="CDD:100101"
misc_feature order(76747..76749,76891..76893,76897..76908,76918..76920,
76924..76929,77059..77064,77071..77076)
/gene="rplK"
/locus_tag="CGSHiEE_00415"
/note="L7/L12 interface [polypeptide binding]; other site"
/db_xref="CDD:100101"
misc_feature order(76795..76797,76807..76809)
/gene="rplK"
/locus_tag="CGSHiEE_00415"
/note="putative thiostrepton binding site; other site"
/db_xref="CDD:100101"
misc_feature order(76999..77001,77008..77010)
/gene="rplK"
/locus_tag="CGSHiEE_00415"
/note="L25 interface [polypeptide binding]; other site"
/db_xref="CDD:100101"
gene 77153..77842
/gene="rplA"
/locus_tag="CGSHiEE_00420"
/db_xref="GeneID:5225007"
CDS 77153..77842
/gene="rplA"
/locus_tag="CGSHiEE_00420"
/note="in Escherichia coli and Methanococcus, this protein
autoregulates expression; the binding site in the mRNA
mimics the binding site in the 23S rRNA"
/codon_start=1
/transl_table=11
/product="50S ribosomal protein L1"
/protein_id="YP_001289961.1"
/db_xref="GI:148825208"
/db_xref="GeneID:5225007"
/translation="MAKLTKKMKAIKAGVDSTKAYEINEAIAVLKQFATAKFVESVDV
AVNLGIDPRKSDQNVRGATVLPHGTGREVRVAVFTQGANADAAKEAGADLVGMEDLAE
QIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKSGQ
IRYRNDKNGIIHTTIGKANFSEVQLKENLQALLVALNKAKPTTAKGIFIKKVSISTTM
GAGVAVDQASL"
misc_feature 77219..77824
/gene="rplA"
/locus_tag="CGSHiEE_00420"
/note="Ribosomal protein L1. The L1 protein, located near
the E-site of the ribosome, forms part of the L1 stalk
along with 23S rRNA. In bacteria and archaea, L1
functions both as a ribosomal protein that binds rRNA, and
as a translation repressor that binds...; Region:
Ribosomal_L1; cd00403"
/db_xref="CDD:88601"
misc_feature order(77258..77266,77273..77275,77279..77281,77285..77287,
77291..77293,77654..77656,77660..77662,77666..77668,
77804..77809,77813..77815)
/gene="rplA"
/locus_tag="CGSHiEE_00420"
/note="mRNA/rRNA interface [nucleotide binding]; other
site"
/db_xref="CDD:88601"
gene 78222..82253
/gene="rpoB"
/locus_tag="CGSHiEE_00425"
/db_xref="GeneID:5224920"
CDS 78222..82253
/gene="rpoB"
/locus_tag="CGSHiEE_00425"
/EC_number="2.7.7.6"
/note="DNA-dependent RNA polymerase catalyzes the
transcription of DNA into RNA using the four
ribonucleoside triphosphates as substrates; beta subunit
is part of the catalytic core which binds with a sigma
factor to produce the holoenzyme"
/codon_start=1
/transl_table=11
/product="DNA-directed RNA polymerase subunit beta"
/protein_id="YP_001289962.1"
/db_xref="GI:148825209"
/db_xref="GeneID:5224920"
/translation="MGYSYSEKKRIRKDFGKRPQVLNVPYLLTIQLDSFDKFIQKDPE
GQQGLEAAFRSVFPIVSNNGYTELQYVDYRLEEPEFDVRECQIRGSTYAAGLRVKLRL
VSYDKESSSRAVKDIKENEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFARIDRRRKLPATIILRALGYTTE
EILNLFFDKITFEISGDKLLMTLVPERLRGETASFDIEANGKVYVERGRRITARHIKA
LEKDNISQVVVPSEYILGKVASKDYVDLESGEIICPANGEISLETLAKLAQAGYTTIE
TLFTNDLDYGPYISETLRVDPTYDKTSALYEIYRMMRPGEPPTPESSEALFNNLFFSA
ERYDLSTVGRMKFNRSLAFPEGEGAGILSNEDIIAVMRKLIDIRNGRGEVDDIDHLGN
RRIRSVGEMAENQFRIGLVRVERAVKERLSLGDLDAITPQDLINPKPISAAVKEFFGS
SQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHNTHYGRLCPIETPEG
PNIGLINSLSAFARTNDYGFLETPYRKVVDGQVTEEIEYLSAIDEANYIIAQANSNLD
ENNRFTDAFVTARGERGESGLYKPEDIHYMDVSTQQVVSVAAALIPFLEHDDANRALM
GANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAVVAKRGGTVQYVDASRIVIKVNED
ETIAGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGDPINRGEVLADGPSTDLGELALG
QNIRVAFMPWNGYNFEDSMLVSERVVQQDRFTTIHIQELSCVARDTKLGSEEITADIP
NVGESALSKLDESGIVYVGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDV
KDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLREAKKDLTEELEILEAGL
FARVRNLLISSGADAAQLDKLDRTKWLEQTIADEEKQNQLEQLAEQYEELRKEFEHKL
EVKRKKIIKGDDLAPGVLKVVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPVEDMPY
DENGQPVEIVLNPLGVPSRMNIGQILETHLGLAAKGIGDQINTMLKQKQEVEKLRSYI
QKAYDLLGNGSQKVDLSTFTDEEVLRLAGNLRKGLPVATPVFDGADEAEIKELLKLGG
LPTSGQITLYDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGG
KAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVSGNQHMDPGT
PESFNVIMKEIRSLGLNIELDEE"
misc_feature 78222..>81047
/gene="rpoB"
/locus_tag="CGSHiEE_00425"
/note="DNA-directed RNA polymerase subunit beta; Reviewed;
Region: rpoB; PRK00405"
/db_xref="CDD:179007"
misc_feature 78300..>78914
/gene="rpoB"
/locus_tag="CGSHiEE_00425"
/note="RNA polymerase beta subunit. RNA polymerases
catalyse the DNA dependent polymerization of RNA.
Prokaryotes contain a single RNA polymerase compared to
three in eukaryotes (not including mitochondrial. and
chloroplast polymerases). Each RNA polymerase...; Region:
RNA_pol_B_RPB2; cl04593"
/db_xref="CDD:156170"
misc_feature <79290..79583
/gene="rpoB"
/locus_tag="CGSHiEE_00425"
/note="RNA polymerase Rpb2, domain 2; Region:
RNA_pol_Rpb2_2; pfam04561"
/db_xref="CDD:203048"
misc_feature <79488..>80357
/gene="rpoB"
/locus_tag="CGSHiEE_00425"
/note="RNA polymerase beta subunit. RNA polymerases
catalyse the DNA dependent polymerization of RNA.
Prokaryotes contain a single RNA polymerase compared to
three in eukaryotes (not including mitochondrial. and
chloroplast polymerases). Each RNA polymerase...; Region:
RNA_pol_B_RPB2; cd00653"
/db_xref="CDD:73223"
misc_feature 80370..>81047
/gene="rpoB"
/locus_tag="CGSHiEE_00425"
/note="RNA polymerase Rpb2, domain 6; Region:
RNA_pol_Rpb2_6; pfam00562"
/db_xref="CDD:201307"
misc_feature <81396..82244
/gene="rpoB"
/locus_tag="CGSHiEE_00425"
/note="RNA polymerase beta subunit. RNA polymerases
catalyse the DNA dependent polymerization of RNA.
Prokaryotes contain a single RNA polymerase compared to
three in eukaryotes (not including mitochondrial. and
chloroplast polymerases). Each RNA polymerase...; Region:
RNA_pol_B_RPB2; cd00653"
/db_xref="CDD:73223"
misc_feature order(81441..81443,81447..81449,81453..81455,81519..81521,
81525..81527,81534..81536,81543..81545,81558..81560,
81570..81572,81783..81785,81864..81866,81888..81896,
81900..81902,81939..81941,81948..81956,81960..81965,
82026..82034,82044..82046,82050..82055,82059..82061,
82065..82082,82086..82103,82113..82115,82182..82184,
82194..82196,82200..82202,82206..82211,82215..82217,
82221..82232,82236..82238,82242..82244)
/gene="rpoB"
/locus_tag="CGSHiEE_00425"
/note="RPB1 interaction site [polypeptide binding]; other
site"
/db_xref="CDD:73223"
misc_feature order(81465..81467,81870..81872)
/gene="rpoB"
/locus_tag="CGSHiEE_00425"
/note="RPB11 interaction site [polypeptide binding]; other
site"
/db_xref="CDD:73223"
misc_feature order(81468..81470,81507..81509,81588..81590,81738..81740,
81744..81746,81852..81854,81903..81905)
/gene="rpoB"
/locus_tag="CGSHiEE_00425"
/note="RPB10 interaction site [polypeptide binding]; other
site"
/db_xref="CDD:73223"
misc_feature order(81468..81476,81483..81485,81489..81494,81867..81890,
81894..81896)
/gene="rpoB"
/locus_tag="CGSHiEE_00425"
/note="RPB3 interaction site [polypeptide binding]; other
site"
/db_xref="CDD:73223"
gene 82391..86641
/locus_tag="CGSHiEE_00430"
/db_xref="GeneID:5224921"
CDS 82391..86641
/locus_tag="CGSHiEE_00430"
/EC_number="2.7.7.6"
/note="DNA-dependent RNA polymerase catalyzes the
transcription of DNA into RNA using the four
ribonucleoside triphosphates as substrates. Subunit beta'
binds to sigma factor allowing it to bind to the -10
region of the promoter"
/codon_start=1
/transl_table=11
/product="DNA-directed RNA polymerase subunit beta'"
/protein_id="YP_001289963.1"
/db_xref="GI:148825210"
/db_xref="GeneID:5224921"
/translation="MKDLVKFLKAQSKTSEDFDVIKIGLASPDMIRSWSFGEVKKPET
INYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRER
MGHIELASPVAHIWFLKSLPSRIGLLLDMPLRDIERVLYFEMYIVTEPGMTDLERGQL
LTEEQYLDAEDRWQDEFEAKMGAEAIQDLLKGMDLEAECEKLREELQETNSETKRKKI
TKRLKLLEAFVQSGNKPEWMVMTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINR
NNRLKRLLDLIAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNRRPLKSLADMIKG
KQGRFRQNLLGKRVDYSGRSVITVGPYLHLHQCGLPKKMALELFRPFIYAKLESRGYA
TTIKAAKKMVEREEAIVWDILAEVIREHPILLNRAPTLHRLGIQAFEPILIEGKAIQL
HPLVCAAFNADFDGDQMAVHVPLTLEAQLEARALMMSTNNVLSPANGDPIIVPSQDVV
LGLYYMTREKVNGKGEGMLLQDPREAEKAYRTGEAELHSRVKVRITEYVKNEAGEFDA
KTTLTDTTIGRAILWMIAPKGMPYSLFNQTLGKKAISKLINEAYRRLGLKEAVMFADQ
IMYTGFAYAARSGSSVGIDDMEIPAKKYEIISAAEEEVAEIQEQFQSGLVTAGERYNK
VIDIWAAANERVAKAMMENLSQEEVINREGNPEKQASFNSIFMMADSGARGSAAQIRQ
LAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLT
RRLVDVAQDLVIVEDDCGTHEGLVMTPLIEGGDEKVPLRELVLGRVAAEDILKPGTEE
VLIPRNTLLDEKLCDVLDANSVDSVKVRSVVTCDTDFGVCAKCYGRDLARGHLINQGE
AVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSVQVKNTGTVHLMNAKFVTNDES
KLVLTSRNTELTITDAFGRTKEHYKVPYGAVLSKGDGQEVTAGETIANWDPHTMPVVS
EVSGFVKFVDIIDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPTIKLVDANGND
IFLPETDVLAQYFLPGKAIVSLDDGAAVKVGEPLARIPQESVGTKDITGGLPRVADLF
EARKPKEPAILAEISGIVSFGKETKGKRRLLITPTEGETYEEMIPKWRQLNVFEGEMV
QRGDVISDGAETPHDILRLRGVRAVTEYIVNEVQDVYRLQGVKINDKHIEVIVRQMLR
KAVITKAYDSEFLEGEQVEVARVKIVNRQREAEGKPPVEFERELLGITKASLATESFI
SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGFAYHQNRHKHRLVDDV
VAKLSEEDEATIADEFVMTADDASASLAEMLNMADDAE"
misc_feature 82433..84952
/locus_tag="CGSHiEE_00430"
/note="DNA-directed RNA polymerase, beta' subunit/160 kD
subunit [Transcription]; Region: RpoC; COG0086"
/db_xref="CDD:30435"
misc_feature 82436..83419
/locus_tag="CGSHiEE_00430"
/note="RNA polymerase Rpb1, domain 1; Region:
RNA_pol_Rpb1_1; pfam04997"
/db_xref="CDD:147265"
misc_feature 83096..83926
/locus_tag="CGSHiEE_00430"
/note="RNA polymerase I subunit A N-terminus; Region:
RPOLA_N; smart00663"
/db_xref="CDD:197824"
misc_feature 83858..84325
/locus_tag="CGSHiEE_00430"
/note="RNA polymerase Rpb1, domain 3; Region:
RNA_pol_Rpb1_3; pfam04983"
/db_xref="CDD:147253"
misc_feature 84410..84685
/locus_tag="CGSHiEE_00430"
/note="RNA polymerase Rpb1, domain 4; Region:
RNA_pol_Rpb1_4; pfam05000"
/db_xref="CDD:203147"
misc_feature 84689..>85522
/locus_tag="CGSHiEE_00430"
/note="RNA polymerase Rpb1, domain 5; Region:
RNA_pol_Rpb1_5; pfam04998"
/db_xref="CDD:147266"
misc_feature 85112..>85210
/locus_tag="CGSHiEE_00430"
/note="Largest subunit of RNA polymerase (RNAP),
C-terminal domain; Region: RNAP_largest_subunit_C;
cl11429"
/db_xref="CDD:142634"
misc_feature 85130..85132
/locus_tag="CGSHiEE_00430"
/note="Rpb1 - Rpb6 interaction site [polypeptide binding];
other site"
/db_xref="CDD:132719"
misc_feature 85787..>85843
/locus_tag="CGSHiEE_00430"
/note="Largest subunit of RNA polymerase (RNAP),
C-terminal domain; Region: RNAP_largest_subunit_C;
cl11429"
/db_xref="CDD:142634"
misc_feature <86036..86479
/locus_tag="CGSHiEE_00430"
/note="Largest subunit (beta') of Bacterial DNA-dependent
RNA polymerase (RNAP), C-terminal domain; Region:
RNAP_beta'_C; cd02655"
/db_xref="CDD:132721"
misc_feature order(86321..86323,86366..86371)
/locus_tag="CGSHiEE_00430"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:132721"
misc_feature order(86411..86413,86429..86431,86447..86449,86456..86461,
86471..86473)
/locus_tag="CGSHiEE_00430"
/note="Rpb1 (beta') - Rpb2 (beta) interaction site
[polypeptide binding]; other site"
/db_xref="CDD:132721"
gene 86836..87780
/locus_tag="CGSHiEE_00435"
/db_xref="GeneID:5224922"
CDS 86836..87780
/locus_tag="CGSHiEE_00435"
/note="COG1275 Tellurite resistance protein and related
permeases"
/codon_start=1
/transl_table=11
/product="potassium-tellurite ethidium and proflavin
transporter"
/protein_id="YP_001289964.1"
/db_xref="GI:148825211"
/db_xref="GeneID:5224922"
/translation="MNTTKPFPIPTGYFGIPLGLAALSLAWLHLENLFPAVRMVSDVL
GIVASAVWILFILMYAYKLRYYFEEVRAEYHCPVRFSFIALIPITTMLVGDIIYRWNP
LIAEVMIWIGTIGQLLFSTLRVSELWQGGVFEQKSTRPPFYLPAVAANFTSASSLALL
GYHDLGHLFFGAGMIAWIIFEPVLLQHLRISSLEPQFRATIGIVLAPAFVCVSAYLSI
NHGEVDTLAKILWGYGFLQLFFLLRLFPWVIEKGLNVGLWGFSFGLASMANSATVFYH
SDVLQGVSIFVFVFSNVMIGLLVLMTIIKLAKGQFFLK"
misc_feature 86863..87765
/locus_tag="CGSHiEE_00435"
/note="Tellurite-resistance/Dicarboxylate Transporter
(TDT) family includes TehA protein; Region: TDT_TehA;
cd09324"
/db_xref="CDD:187764"
misc_feature 87619..87621
/locus_tag="CGSHiEE_00435"
/note="gating phenylalanine in ion channel; other site"
/db_xref="CDD:187764"
gene complement(87835..88554)
/locus_tag="CGSHiEE_00440"
/db_xref="GeneID:5224923"
CDS complement(87835..88554)
/locus_tag="CGSHiEE_00440"
/note="COG1720 Uncharacterized conserved protein"
/codon_start=1
/transl_table=11
/product="potassium-tellurite ethidium and proflavin
transporter"
/protein_id="YP_001289965.1"
/db_xref="GI:148825212"
/db_xref="GeneID:5224923"
/translation="MNDLTLSPVAIIHTPYKEKFSVPRQPNLVEDGVGIVELLPPYNS
PETVRGLEQFSHLWLIFQFDQIQQGKWQPTVRPPRLGGNQRVGVFASRATHRPNPLGL
SKVKLRQVECINGNVFLHLGAVDLVDGTPIFDIKPYIAYADSEPNAQSSFAQEKPPAK
LTVEFTEQAKSAVKKREEKRPHLSRFIRQVLEQDPRPAYQQGKPSDRIYGTSLYEFNV
KWRIKASTLDCVEVIEIEKDK"
misc_feature complement(88141..88533)
/locus_tag="CGSHiEE_00440"
/note="Escherichia coli YaeB and related proteins; Region:
UPF0066; cd09281"
/db_xref="CDD:187753"
misc_feature complement(order(88141..88158,88255..88257,88261..88263,
88267..88269,88279..88296,88369..88371,88381..88383,
88402..88404,88408..88416,88528..88533))
/locus_tag="CGSHiEE_00440"
/note="homodimer interaction site [polypeptide binding];
other site"
/db_xref="CDD:187753"
misc_feature complement(order(88165..88167,88180..88182,88249..88251,
88255..88257,88279..88281,88363..88368,88372..88374))
/locus_tag="CGSHiEE_00440"
/note="cofactor binding site; other site"
/db_xref="CDD:187753"
gene 88616..89527
/locus_tag="CGSHiEE_00445"
/db_xref="GeneID:5224924"
CDS 88616..89527
/locus_tag="CGSHiEE_00445"
/note="catalyzes the formation of dimethylmenaquinone from
1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate"
/codon_start=1
/transl_table=11
/product="1,4-dihydroxy-2-naphthoate
octaprenyltransferase"
/protein_id="YP_001289966.1"
/db_xref="GI:148825213"
/db_xref="GeneID:5224924"
/translation="MTNEKLKMWWETARPKTLPLALASIFTGSALGYWANPQGFNGLV
MALCLLTTILLQVLSNFANDYGDHQKGSDTEERIGPLRGIQKGAISAKELKWGLILMV
MASFLSGSFLIGIAYENLSDLFAFAGLGILAIVAAITYTVGVKPYGYMGLGDISVLVF
FGLLGVGGTYYLQTHSIASHIILPAIGSGLLASAVLNINNLRDIEQDAKAGKNTLAVR
LGAYKGRVYHCILLSVAALCYLAFAVATAISWTNYLFVLAMPLLAKHAIFVYRSQQPS
ELRPMLAQMSMISLLINILFSLGLLIG"
misc_feature 88655..89476
/locus_tag="CGSHiEE_00445"
/note="1,4-dihydroxy-2-naphthoate octaprenyltransferase;
Region: menA; TIGR00751"
/db_xref="CDD:129834"
gene 89578..90066
/locus_tag="CGSHiEE_00450"
/db_xref="GeneID:5224925"
CDS 89578..90066
/locus_tag="CGSHiEE_00450"
/note="regulator of RNase E; increases half-life and
abundance of RNAs; interacts with RNase E possibly
inhibiting catalytic activity"
/codon_start=1
/transl_table=11
/product="ribonuclease activity regulator protein RraA"
/protein_id="YP_001289967.1"
/db_xref="GI:148825214"
/db_xref="GeneID:5224925"
/translation="MFIDTSELCDLYAEQVDVVEPIFSSFGGVSNFYGKVTTVKCFES
NGLIAEVLEENGEGRVLVIDGGGAVRRGLIDAELAQLAVDNGWEGIIVYGAVRQIQQL
ENLDIGIHALAPIPVSADESSAGESDIPVNFGGVTFFPEDYIYADLTGIILSQEPLDL
ED"
misc_feature 89578..90054
/locus_tag="CGSHiEE_00450"
/note="ribonuclease activity regulator protein RraA;
Provisional; Region: PRK09372"
/db_xref="CDD:181806"
gene complement(90201..90752)
/locus_tag="CGSHiEE_00455"
/db_xref="GeneID:5224884"
CDS complement(90201..90752)
/locus_tag="CGSHiEE_00455"
/note="COG2862 Predicted membrane protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289968.1"
/db_xref="GI:148825215"
/db_xref="GeneID:5224884"
/translation="MKENKPVDPYAKYNEQSNIIAKIIFASRWLQVPIYLGLIVTLAI
YSYKFIKGLWELVINVNDMDSNTIMLGVLNLIDVVMIANLLVMVTIGGYEIFVSKLRT
RNHPDQPEWMSHVNATVLKVKLSMSIIGISSIHMLQTFVNASNMPEKTMMWQLLLHLG
FLVSAIALAYTDKILYSTSHKTH"
misc_feature complement(90204..90698)
/locus_tag="CGSHiEE_00455"
/note="hypothetical protein; Provisional; Region:
PRK05208"
/db_xref="CDD:179964"
gene complement(90860..91858)
/locus_tag="CGSHiEE_00460"
/db_xref="GeneID:5224885"
CDS complement(90860..91858)
/locus_tag="CGSHiEE_00460"
/note="COG1609 Transcriptional regulators"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289969.1"
/db_xref="GI:148825216"
/db_xref="GeneID:5224885"
/translation="MATMKDIARLAQVSTSTVSHVINGSRFVSDEIREKVMRIVAELN
YTPSAVARSLKVRETKTIGLLVTATNNPFFAEVMAGVEQYCQKNQYNLIIATTGGDAK
RLQQNLQTLMHKQVDGLLLMCGDSRFQADIELAISLPLVVMDWWFTELNADKILENSA
LGGYLATKALIDAGHRKIGIITGNLKKSVAQNRLQGYKNALSEAKIALNPHWIVESHF
DFEGGVLGIQSLLTQSSRPTAVFCCSDTIAVGAYQAIQQQGLRIPQDLSIMGYDDIEL
ARYLSPPLSTICQPKAELGKLAVETLLQRIKNPNENYRTLVLEPTCVLRESIYSFK"
misc_feature complement(90875..91849)
/locus_tag="CGSHiEE_00460"
/note="transcriptional repressor RbsR; Provisional;
Region: PRK10423"
/db_xref="CDD:182448"
misc_feature complement(91694..91846)
/locus_tag="CGSHiEE_00460"
/note="Helix-turn-helix (HTH) DNA binding domain of the
LacI family of transcriptional regulators; Region:
HTH_LacI; cd01392"
/db_xref="CDD:143331"
misc_feature complement(order(91694..91699,91703..91708,91715..91717,
91724..91726,91763..91765,91772..91777,91790..91792,
91799..91804,91808..91822,91844..91846))
/locus_tag="CGSHiEE_00460"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:143331"
misc_feature complement(91697..91726)
/locus_tag="CGSHiEE_00460"
/note="domain linker motif; other site"
/db_xref="CDD:143331"
misc_feature complement(90878..91678)
/locus_tag="CGSHiEE_00460"
/note="Ligand-binding domain of purine repressor, PurR,
which functions as the master regulatory protein of de
novo purine nucleotide biosynthesis in Escherichia coli;
Region: PBP1_PurR; cd06275"
/db_xref="CDD:107270"
misc_feature complement(order(90881..90883,91022..91027,91031..91033,
91088..91090,91100..91102,91112..91114,91196..91198,
91517..91519,91538..91540,91577..91585,91589..91591,
91601..91603,91649..91651))
/locus_tag="CGSHiEE_00460"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:107270"
misc_feature complement(order(91043..91045,91205..91207,91280..91282,
91292..91294,91298..91300,91640..91642))
/locus_tag="CGSHiEE_00460"
/note="ligand binding site [chemical binding]; other site"
/db_xref="CDD:107270"
gene complement(91885..92805)
/locus_tag="CGSHiEE_00465"
/db_xref="GeneID:5224886"
CDS complement(91885..92805)
/locus_tag="CGSHiEE_00465"
/EC_number="2.7.1.15"
/note="catalyzes the formation of D-ribose 5-phosphate
from ribose"
/codon_start=1
/transl_table=11
/product="ribokinase"
/protein_id="YP_001289970.1"
/db_xref="GI:148825217"
/db_xref="GeneID:5224886"
/translation="MRKTLTVLGSINADHVISVPYFAKPSETLTGQNYQIAYGGKGAN
QAVAATRLGAKVAFISCIGSDSIGKTMKNAFAQEGIDTTHINTVSQEMTGMAFIQVAK
SSENSIVLASGANAHLGEMVVRQSEAQIAQSDCLLMQLETPLSGVELAAQIAKKNGVK
VVLNPAPAQILSDELLSLIDIITPNETEAEILTGVQVSDEQSAVEAAQVFHKKGIDCV
MITLGEKGVFVSQNGETRIINGFRVKAVDTTAAGDTFNGGFVTALLEGQSFENAVRFG
QAAAAISVTRKGAQPSIPTRQETLEFLAHV"
misc_feature complement(91894..92793)
/locus_tag="CGSHiEE_00465"
/note="Sugar kinases, ribokinase family [Carbohydrate
transport and metabolism]; Region: RbsK; COG0524"
/db_xref="CDD:30870"
misc_feature complement(91921..92793)
/locus_tag="CGSHiEE_00465"
/note="Ribokinase catalyses the phosphorylation of ribose
to ribose-5-phosphate using ATP. This reaction is the
first step in the ribose metabolism. It traps ribose
within the cell after uptake and also prepares the sugar
for use in the synthesis of nucleotides...; Region:
ribokinase; cd01174"
/db_xref="CDD:29358"
misc_feature complement(order(91939..91941,92047..92049,92056..92061,
92383..92385,92476..92478,92482..92484,92512..92514,
92518..92520,92674..92676,92683..92691,92764..92766,
92770..92772))
/locus_tag="CGSHiEE_00465"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:29358"
misc_feature complement(order(92305..92307,92470..92493,92509..92517,
92521..92523,92683..92685,92722..92742,92755..92757,
92761..92763))
/locus_tag="CGSHiEE_00465"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:29358"
misc_feature complement(order(91954..91956,91963..91968,91975..91977,
92041..92043,92050..92055,92062..92064,92071..92073,
92089..92091,92128..92130,92137..92145,92251..92253))
/locus_tag="CGSHiEE_00465"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:29358"
gene complement(92903..93781)
/locus_tag="CGSHiEE_00470"
/db_xref="GeneID:5224887"
CDS complement(92903..93781)
/locus_tag="CGSHiEE_00470"
/note="periplasmic substrate-binding component of the
ATP-dependent ribose transport system"
/codon_start=1
/transl_table=11
/product="D-ribose transporter subunit RbsB"
/protein_id="YP_001289971.1"
/db_xref="GI:148825218"
/db_xref="GeneID:5224887"
/translation="MKKLTALTSAVLLGLAVSSSTSAQDTIALAVSTLDNPFFVTLKD
GAQKKADELGYKLVVLDSQNDPAKELANVEDLTVRGAKILLINPTDSEAVGNAVAIAN
RKHIPVITLDRGAAKGNVVSHIASDNIAGGKMAGDFIAQKLGDNAKVIQLEGIAGTSA
ARERGEGFKQAIDAHKFNVLASQPADFDRTKGLNVTENLLASKGDVQAIFAQNDEMAL
GALRAVKAANKKVLIVGFDGTDDGVKAVKSGKMAATIAQQPELIGSLGVVTADKILKG
EKVEAKIPVDLKVISE"
misc_feature complement(92906..93712)
/locus_tag="CGSHiEE_00470"
/note="D-ribose transporter subunit RbsB; Provisional;
Region: PRK10653"
/db_xref="CDD:182620"
misc_feature complement(92912..93706)
/locus_tag="CGSHiEE_00470"
/note="Periplasmic sugar-binding domain of the
thermophilic Thermoanaerobacter tengcongensis ribose
binding protein (ttRBP) and its mesophilic homologs;
Region: PBP1_ribose_binding; cd06323"
/db_xref="CDD:107318"
misc_feature complement(order(93011..93013,93071..93073,93143..93145,
93221..93223,93290..93292,93302..93304,93443..93448,
93521..93523,93665..93670,93674..93676))
/locus_tag="CGSHiEE_00470"
/note="ligand binding site [chemical binding]; other site"
/db_xref="CDD:107318"
misc_feature complement(order(93179..93181,93233..93238,93245..93250,
93284..93286,93296..93298))
/locus_tag="CGSHiEE_00470"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:107318"
gene complement(93801..94769)
/gene="rbsC"
/locus_tag="CGSHiEE_00475"
/db_xref="GeneID:5224888"
CDS complement(93801..94769)
/gene="rbsC"
/locus_tag="CGSHiEE_00475"
/note="functions to transport ribose at high affinity;
forms a complex with RbsA2C2B"
/codon_start=1
/transl_table=11
/product="ribose ABC transporter permease protein"
/protein_id="YP_001289972.1"
/db_xref="GI:148825219"
/db_xref="GeneID:5224888"
/translation="MKNETSNFQIGRFLIEQRSFIALIILIAIVSMINPDFFSVDNIL
NILRQTSVNAIIAVGMTFVILIAGIDLSVGSVLALTGAIAASMVSIELPIFLVIPVVL
LIGTLLGGISGVIVAKGKVQAFIATLVTMTLLRGITMVYTDGRPITTGFSDNADLFAS
IGTGYVLGIPVPIWIMSIVFAVAWYILKHTPIGRYIYALGGNEAATQLSGINVNKIKV
FVFAVSGFLSALAGLIVTSRLSSAQPTAGVSYELDAIAAVVVGGTSLMGGKGRVMGTL
IGALIIGFLNNALNLLDISSYYQMIAKALVILVAVLADNYLGTKKL"
misc_feature complement(93861..94622)
/gene="rbsC"
/locus_tag="CGSHiEE_00475"
/note="Transmembrane subunit (TM) of Escherichia coli AraH
and related proteins. E. coli AraH is the TM of a
Periplasmic Binding Protein (PBP)-dependent ATP-Binding
Cassette (ABC) transporter involved in the uptake of the
monosaccharide arabinose. This group...; Region:
TM_PBP1_transp_AraH_like; cd06579"
/db_xref="CDD:119321"
misc_feature complement(94104..94160)
/gene="rbsC"
/locus_tag="CGSHiEE_00475"
/note="TM-ABC transporter signature motif; other site"
/db_xref="CDD:119321"
gene complement(94785..96266)
/locus_tag="CGSHiEE_00480"
/db_xref="GeneID:5224878"
CDS complement(94785..96266)
/locus_tag="CGSHiEE_00480"
/note="with RbsBCD acts to import ribose into the cell;
RbsA contains 2 ATP-binding domain"
/codon_start=1
/transl_table=11
/product="D-ribose transporter ATP binding protein"
/protein_id="YP_001289973.1"
/db_xref="GI:148825220"
/db_xref="GeneID:5224878"
/translation="METLLKISGVDKSFPGVKALNNACLSVYAGRVMALMGENGAGKS
TLMKVLTGIYSKDAGTIEYLNRSVNFNGPKASQEAGISIIHQELNLVGNLTIAENIFL
GREFKTSWGAINWQKMHQEADKLLSRLGVTHSSKQLCAELSIGEQQMVEIAKALSFES
KVIIMDEPTDALTDTETEALFNVIRELKAENRGIVYISHRLKEIFQICDDVTVLRDGQ
FIGERIVAEITEDDLIEMMVGRRLDEQYPHLSQEKGECVLDVKHVSGSSIDDVSFKLH
AGEIVGVSGLMGAGRTELGKLLYGALPKTAGKVRLKNQEIENLSPQDGLDNGIVYISE
DRKGDGLVLGMSVKENMSLTSLDHFSNRGSIRHQAEKMAVDDFILMFNIKTPNRDQQV
GLLSGGNQQKVAIARGLMTRPNVLILDEPTRGVDVGAKKEIYQLINEFKKEGLSILMI
SSDMPEVLGMSDRVLVMREGKISAEFSREEATQEKLLAAAIGK"
misc_feature complement(94788..96266)
/locus_tag="CGSHiEE_00480"
/note="D-ribose transporter ATP binding protein;
Provisional; Region: PRK10762"
/db_xref="CDD:182707"
misc_feature complement(95601..96254)
/locus_tag="CGSHiEE_00480"
/note="This family represents the domain I of the
carbohydrate uptake proteins that transport only
monosaccharides (Monos). The Carb_Monos family is
involved in the uptake of monosaccharides, such as
pentoses (such as xylose, arabinose, and ribose) and
hexoses...; Region: ABC_Carb_Monos_I; cd03216"
/db_xref="CDD:72975"
misc_feature complement(96135..96158)
/locus_tag="CGSHiEE_00480"
/note="Walker A/P-loop; other site"
/db_xref="CDD:72975"
misc_feature complement(order(95670..95672,95766..95771,95907..95909,
96132..96140,96144..96149))
/locus_tag="CGSHiEE_00480"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:72975"
misc_feature complement(order(95907..95912,96015..96020))
/locus_tag="CGSHiEE_00480"
/note="Q-loop/lid; other site"
/db_xref="CDD:72975"
misc_feature complement(95814..95843)
/locus_tag="CGSHiEE_00480"
/note="ABC transporter signature motif; other site"
/db_xref="CDD:72975"
misc_feature complement(95766..95783)
/locus_tag="CGSHiEE_00480"
/note="Walker B; other site"
/db_xref="CDD:72975"
misc_feature complement(95748..95759)
/locus_tag="CGSHiEE_00480"
/note="D-loop; other site"
/db_xref="CDD:72975"
misc_feature complement(95664..95684)
/locus_tag="CGSHiEE_00480"
/note="H-loop/switch region; other site"
/db_xref="CDD:72975"
misc_feature complement(94851..95507)
/locus_tag="CGSHiEE_00480"
/note="This family represents domain II of the
carbohydrate uptake proteins that transport only
monosaccharides (Monos). The Carb_Monos family is
involved in the uptake of monosaccharides, such as
pentoses (such as xylose, arabinose, and ribose) and
hexoses; Region: ABC_Carb_Monos_II; cd03215"
/db_xref="CDD:72974"
gene complement(96280..96699)
/locus_tag="CGSHiEE_00485"
/db_xref="GeneID:5224879"
CDS complement(96280..96699)
/locus_tag="CGSHiEE_00485"
/note="cytoplasmic mutarotase that catalyzes the
conversion between beta-pyran and beta-furan forms of
D-ribose; RbsD is required for efficient ribose
utilization in E. coli; rbsD-mutant E. coli strains are
unable to use ribose as a sole carbon source"
/codon_start=1
/transl_table=11
/product="D-ribose pyranase"
/protein_id="YP_001289974.1"
/db_xref="GI:148825221"
/db_xref="GeneID:5224879"
/translation="MKKTMLLNAQLSRCIASVGHTESLTICDAGLPIPLSVERIDLAL
TAGVPSFLQTLNVVTNEMYVERVVIAEEIKEKNPEILTALLTQLQQLESHQGNQIQVE
FVSHETFKKFTLESKAIVRTGECSPYANVILYSGVPF"
misc_feature complement(96283..96699)
/locus_tag="CGSHiEE_00485"
/note="D-ribose pyranase; Provisional; Region: PRK11797"
/db_xref="CDD:183318"
gene complement(96863..98305)
/locus_tag="CGSHiEE_00490"
/db_xref="GeneID:5224880"
CDS complement(96863..98305)
/locus_tag="CGSHiEE_00490"
/note="COG1322 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="DNA recombination protein RmuC"
/protein_id="YP_001289975.1"
/db_xref="GI:148825222"
/db_xref="GeneID:5224880"
/translation="MSENLLLFSLLAVVIILILLLILRQQKYTHLHQELSKTTQDYNQ
LASKFDELSSIKNQFEQQTIKVQTENQGLQYRLTERDEQIHHLTQERQNLTEKLTALS
QELTGLQTTLTEKEKYFSAQQQNFEQSKLQLSVEFQNLANRILDEKSRSFSQSNQTAL
ETLLKPFREQIEGFQKRVNEIHSESVKGNAGLEAEIKKVLEIGLNMSQEASNLTSALK
GEKKTLGNWGEVQLERALQLAGLEENVHYRAQAHFKDEQGGRNYPDFVLNLPDEKHLI
IDSKMSLVAYESAVNSEDDFERERLLKEHISALKTHINDLHKKDYSNLIGMRSPNFVL
MFIAVEPAYIEALKAAPALFNYGYERNVIMVSHTTLMPILRTVANLWRIERGNAEAKE
IAEKAGEIYNQICLVTERLSKLGNTLSTVSNQYNSTVTALVGQQGLVGKVERFKTLSA
KANKTMPDVDLLNNQLDLARLNVLNQENLQ"
misc_feature complement(96866..98071)
/locus_tag="CGSHiEE_00490"
/note="Predicted nuclease of restriction endonuclease-like
fold, RmuC family [General function prediction only];
Region: COG1322"
/db_xref="CDD:31513"
misc_feature complement(96932..97837)
/locus_tag="CGSHiEE_00490"
/note="RmuC family; Region: RmuC; pfam02646"
/db_xref="CDD:111535"
gene complement(98470..99660)
/locus_tag="CGSHiEE_00495"
/db_xref="GeneID:5224881"
CDS complement(98470..99660)
/locus_tag="CGSHiEE_00495"
/note="COG0665 Glycine/D-amino acid oxidases
(deaminating)"
/codon_start=1
/transl_table=11
/product="oxidoreductase OrdL"
/protein_id="YP_001289976.1"
/db_xref="GI:148825223"
/db_xref="GeneID:5224881"
/translation="MCDRSWIFWFICSIRTGGERKKVIVLEGARVGFGASGRSGGQAI
NGFEEGIDEYVKQVGEDKAHKLWNMSLETIDIIDERIEKYSIQCDWKKGYATLALNER
RMDDLIEMEKESHKNFGYQNMQLWDKTKLKQHLGSDIYVGGLFDSNSGHLHPLNYCLG
LAKACVDLGVQIFEQSPVVDMVEKNGCVEVKTAKSAVISQDVILATNAYIDALPKSIH
HGINRKILPVESFIIATEPLSQAVADSVINNGMSVCDNNLLLDYYRLSADNRLLFGSD
SSSEKDMVAVMRKNMLCVFPQLENVKIDYGWAGPIDMTLNSTPHFGRISPHIYFAHGY
SGHGVALTGLAGRIVAEAILGDDERLSIFEGLKVPSVYGGRIIKDLATKIGVQYYKFL
DKYR"
misc_feature complement(98590..99636)
/locus_tag="CGSHiEE_00495"
/note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
NADB_Rossmann; cl09931"
/db_xref="CDD:213117"
misc_feature complement(98746..99597)
/locus_tag="CGSHiEE_00495"
/note="FAD dependent oxidoreductase; Region: DAO;
pfam01266"
/db_xref="CDD:201696"
gene complement(99582..99764)
/locus_tag="CGSHiEE_00500"
/db_xref="GeneID:5224882"
CDS complement(99582..99764)
/locus_tag="CGSHiEE_00500"
/note="COG0665 Glycine/D-amino acid oxidases
(deaminating)"
/codon_start=1
/transl_table=11
/product="oxidoreductase OrdL"
/protein_id="YP_001289977.1"
/db_xref="GI:148825224"
/db_xref="GeneID:5224882"
/translation="MLNFAYQEHVRSYYFDSRNQDFQFPPLTQIEHADVCVIGAGFFG
LSAALELAEKGKKSLS"
misc_feature complement(<99594..99665)
/locus_tag="CGSHiEE_00500"
/note="FAD dependent oxidoreductase; Region: DAO;
pfam01266"
/db_xref="CDD:201696"
misc_feature complement(<99594..99665)
/locus_tag="CGSHiEE_00500"
/note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
NADB_Rossmann; cl09931"
/db_xref="CDD:213117"
gene 99904..100956
/locus_tag="CGSHiEE_00505"
/db_xref="GeneID:5224883"
CDS 99904..100956
/locus_tag="CGSHiEE_00505"
/note="COG0687 Spermidine/putrescine-binding periplasmic
protein"
/codon_start=1
/transl_table=11
/product="cytoplasmic sugar-binding protein"
/protein_id="YP_001289978.1"
/db_xref="GI:148825225"
/db_xref="GeneID:5224883"
/translation="MKKFFAHSLKNLFLSTAALFAASAFANNKLYVYNWTDYVPSDLV
AQFSKETGIEVIYSTFESNEEMYAKLKLTQNTGSSYDLVFPSSYYVNKMIKEKMLQPI
DQSKLTNIHQIPKHLLNKEFDPENKYSLPYVYGLTGIEVNADEIDPKTITSWADLWKP
EFKGKVLMTSDAREVFHVALLLDGKSPNTTNEEDIKTAYERLEKLLPNVATFNSDSPE
VPYVQGEVAIGMIWNGSAYLAQKENQSLQFVYPKEGAIFWMDNYAIPNSAQNVEGAHK
FIDFLLRPENAKIVIERMGFSMPNNGAKTLLSAEVANDPKLFPPAEEVEKGIMQGDVG
EAVDIYEKYWSKLKTN"
misc_feature 99991..100947
/locus_tag="CGSHiEE_00505"
/note="spermidine/putrescine ABC transporter periplasmic
substrate-binding protein; Reviewed; Region: potD;
PRK09501"
/db_xref="CDD:181913"
misc_feature 100141..100881
/locus_tag="CGSHiEE_00505"
/note="Bacterial extracellular solute-binding protein;
Region: SBP_bac_6; pfam13343"
/db_xref="CDD:205523"
gene complement(101026..102360)
/gene="hslU"
/locus_tag="CGSHiEE_00510"
/db_xref="GeneID:5224873"
CDS complement(101026..102360)
/gene="hslU"
/locus_tag="CGSHiEE_00510"
/note="heat shock protein involved in degradation of
misfolded proteins"
/codon_start=1
/transl_table=11
/product="ATP-dependent protease ATP-binding subunit HslU"
/protein_id="YP_001289979.1"
/db_xref="GI:148825226"
/db_xref="GeneID:5224873"
/translation="MSEMTPREIVSELDQHIIGQADAKRAVAIALRNRWRRMQLQEPL
RHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRD
LTDSAMKLVRQQEIAKNRARAEDAAEERILDALLPPAKNQWGEVESHDSHSSTRQAFR
KKLREGQLDDKEIEIDVSAGVSMGVEIMAPPGMEEMTNQLQSLFQNLGSDKTKKRKMK
IKDGLKALIDDEAAKLINPEELKQKAIDAVEQNGIVFIDEIDKICKKGEYSGADVSRE
GVQRDLLPLVEGSTVSTKHGMVKTDHILFIASGAFQVARPSDLIPELQGRLPIRVELT
ALSAADFERILTEPHASLTEQYKALMATEGVNIAFTTDAVKKIAEAAFCVNEKTENIG
ARRLHTVMERLMDKISFSASDMNGQTVNIDAAYVADALGEVVENEDLSRFIL"
misc_feature complement(101029..102360)
/gene="hslU"
/locus_tag="CGSHiEE_00510"
/note="ATP-dependent protease ATP-binding subunit HslU;
Provisional; Region: hslU; PRK05201"
/db_xref="CDD:179962"
misc_feature complement(<102052..102309)
/gene="hslU"
/locus_tag="CGSHiEE_00510"
/note="The AAA+ (ATPases Associated with a wide variety of
cellular Activities) superfamily represents an ancient
group of ATPases belonging to the ASCE (for additional
strand, catalytic E) division of the P-loop NTPase fold.
The ASCE division also includes ABC; Region: AAA; cd00009"
/db_xref="CDD:99707"
misc_feature complement(102169..102192)
/gene="hslU"
/locus_tag="CGSHiEE_00510"
/note="Walker A motif; other site"
/db_xref="CDD:99707"
misc_feature complement(102166..102189)
/gene="hslU"
/locus_tag="CGSHiEE_00510"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:99707"
misc_feature complement(101362..>101682)
/gene="hslU"
/locus_tag="CGSHiEE_00510"
/note="The AAA+ (ATPases Associated with a wide variety of
cellular Activities) superfamily represents an ancient
group of ATPases belonging to the ASCE (for additional
strand, catalytic E) division of the P-loop NTPase fold.
The ASCE division also includes ABC; Region: AAA; cd00009"
/db_xref="CDD:99707"
misc_feature complement(101587..101604)
/gene="hslU"
/locus_tag="CGSHiEE_00510"
/note="Walker B motif; other site"
/db_xref="CDD:99707"
misc_feature complement(101383..101385)
/gene="hslU"
/locus_tag="CGSHiEE_00510"
/note="arginine finger; other site"
/db_xref="CDD:99707"
misc_feature complement(101092..101355)
/gene="hslU"
/locus_tag="CGSHiEE_00510"
/note="C-terminal, D2-small domain, of ClpB protein;
Region: ClpB_D2-small; smart01086"
/db_xref="CDD:198154"
gene complement(102371..102898)
/locus_tag="CGSHiEE_00515"
/db_xref="GeneID:5224874"
CDS complement(102371..102898)
/locus_tag="CGSHiEE_00515"
/note="heat shock protein involved in degradation of
misfolded proteins"
/codon_start=1
/transl_table=11
/product="ATP-dependent protease peptidase subunit"
/protein_id="YP_001289980.1"
/db_xref="GI:148825227"
/db_xref="GeneID:5224874"
/translation="MTTIVSVRRKGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVL
AGFAGGTADAFTLFELFERKLEMHQGHLLKSAVELAKDWRTDRALRKLEAMLIVADEK
ESLIITGIGDVVQPEEDQILAIGSGGNYALSAARALVENTELSAHEIVEKSLRIAGDI
CVFTNTNFTIEELPN"
misc_feature complement(102380..102826)
/locus_tag="CGSHiEE_00515"
/note="Protease HslV and the ATPase/chaperone HslU are
part of an ATP-dependent proteolytic system that is the
prokaryotic homolog of the proteasome. HslV is a dimer of
hexamers (a dodecamer) that forms a central proteolytic
chamber with active sites on the...; Region:
protease_HslV; cd01913"
/db_xref="CDD:48442"
misc_feature complement(order(102413..102415,102419..102424,
102431..102433,102443..102445,102476..102478,
102500..102502,102509..102514,102554..102556,
102566..102568,102647..102649,102818..102826))
/locus_tag="CGSHiEE_00515"
/note="HslU subunit interaction site [polypeptide
binding]; other site"
/db_xref="CDD:48442"
gene 103118..103825
/gene="aphA"
/locus_tag="CGSHiEE_00520"
/db_xref="GeneID:5224875"
CDS 103118..103825
/gene="aphA"
/locus_tag="CGSHiEE_00520"
/EC_number="3.1.3.2"
/note="Class B; non-specific; catalyzes the
dephosphorylation of organic phosphomonoesters; also has
phosphotransferase activity"
/codon_start=1
/transl_table=11
/product="acid phosphatase/phosphotransferase"
/protein_id="YP_001289981.1"
/db_xref="GI:148825228"
/db_xref="GeneID:5224875"
/translation="MKNVMKLSVIALLTAAAVPAMAGKTEPYTQSGTNAREMLQEQAI
HWISVDQIKQSLEGKAPINVSFDIDDTVLFSSPCFYHGQQKFSPGKHDYLKNQDFWNE
VNAGCDKYSIPKQIAIDLINMHQARGDQVYFFTGRTAGKVDGVTPILEKTFNIKNMHP
VEFMGSRERTTKYNKTPAIISHKVSIHYGDSDDDVLAAKEAGVRGIRLMRAANSTYQP
MPTLGGYGEEVLINSSY"
misc_feature 103184..103822
/gene="aphA"
/locus_tag="CGSHiEE_00520"
/note="acid phosphatase/phosphotransferase; Provisional;
Region: aphA; PRK11009"
/db_xref="CDD:182897"
gene complement(103916..104227)
/gene="aphA"
/locus_tag="CGSHiEE_00525"
/db_xref="GeneID:5224876"
CDS complement(103916..104227)
/gene="aphA"
/locus_tag="CGSHiEE_00525"
/EC_number="3.1.3.2"
/note="COG2801 Transposase and inactivated derivatives"
/codon_start=1
/transl_table=11
/product="acid phosphatase/phosphotransferase"
/protein_id="YP_001289982.1"
/db_xref="GI:148825229"
/db_xref="GeneID:5224876"
/translation="MENLLRAENSTNKKDLKTQNPILHSDQGWQYQMVGYQAILRENS
IQQNMSRKGNYLDNNAMENFFGRLKTECYYDKRFETFKQLKKQLMSIFIITTMTAFRG
N"
misc_feature complement(104012..>104164)
/gene="aphA"
/locus_tag="CGSHiEE_00525"
/note="Integrase core domain; Region: rve; pfam00665"
/db_xref="CDD:201381"
misc_feature complement(<103964..104044)
/gene="aphA"
/locus_tag="CGSHiEE_00525"
/note="Integrase core domain; Region: rve_3; cl15866"
/db_xref="CDD:210266"
gene complement(104744..105247)
/locus_tag="CGSHiEE_00530"
/db_xref="GeneID:5224877"
CDS complement(104744..105247)
/locus_tag="CGSHiEE_00530"
/note="catalyzes the hydrolysis of S-ribosylhomocysteine
to homocysteine and autoinducer-2"
/codon_start=1
/transl_table=11
/product="S-ribosylhomocysteinase"
/protein_id="YP_001289983.1"
/db_xref="GI:148825230"
/db_xref="GeneID:5224877"
/translation="MPLLDSFKVDHTKMNAPAVRIAKTMRTPKGDNITVFDLRFCIPN
KEILSPKGIHTLEHLFAGFMRDHLNGDSIEIIDISPMGCRTGFYMSLIGTPNEQEVSE
AWLASMQDVLGVQDQASIPELNIYQCGSYTEHSLEDAHEIAKNVIARGIGVNKNEDLS
LDNSLLK"
misc_feature complement(104765..105247)
/locus_tag="CGSHiEE_00530"
/note="S-ribosylhomocysteinase; Provisional; Region:
PRK02260"
/db_xref="CDD:179399"
gene complement(105432..105848)
/locus_tag="CGSHiEE_00535"
/db_xref="GeneID:5225182"
CDS complement(105432..105848)
/locus_tag="CGSHiEE_00535"
/note="COG1238 Predicted membrane protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289984.1"
/db_xref="GI:148825231"
/db_xref="GeneID:5225182"
/translation="MFISAFLSATVLPGNSEVIFVALAVPKLMLGSLFNADILALILI
ATAGNSLGSLTTYGIGRWMPKFDPKNYRTLWAINQLRRYGAIALLLSWLPVVGDLFCA
IAGWLRLNFVTSSLFIFLGKMVRYVALLFLSTPFLL"
misc_feature complement(105441..105848)
/locus_tag="CGSHiEE_00535"
/note="Predicted membrane protein [Function unknown];
Region: COG1238"
/db_xref="CDD:31431"
gene complement(105906..106508)
/locus_tag="CGSHiEE_00540"
/db_xref="GeneID:5224868"
CDS complement(105906..106508)
/locus_tag="CGSHiEE_00540"
/codon_start=1
/transl_table=11
/product="putative phosphatase/phosphohexomutase"
/protein_id="YP_001289985.1"
/db_xref="GI:148825232"
/db_xref="GeneID:5224868"
/translation="MLDYEIFNPYEGLIFDMDGTLIDTMPVHAQAWTMVGKKFGYEFD
FQIMYNFGGATVRTIAGEMMKAANMPLDRIEDVLAAKRELSYQLIPTQSKLLPTFEIV
KYFHQKKPMALGSGSHRKIIDMLMDKLAIAPYFNAIVSADDVKEHKPHPETFLRCAEL
IQANPSRCIVFEDADLGVQAGLSAGMDVFDVRTREIISPR"
misc_feature complement(105936..106481)
/locus_tag="CGSHiEE_00540"
/note="beta-phosphoglucomutase family hydrolase; Region:
PGMB-YQAB-SF; TIGR02009"
/db_xref="CDD:162658"
misc_feature complement(105948..106241)
/locus_tag="CGSHiEE_00540"
/note="Haloacid dehalogenase-like hydrolases. The haloacid
dehalogenase-like (HAD) superfamily includes L-2-haloacid
dehalogenase, epoxide hydrolase, phosphoserine
phosphatase, phosphomannomutase, phosphoglycolate
phosphatase, P-type ATPase, and many others; Region:
HAD_like; cd01427"
/db_xref="CDD:119389"
misc_feature complement(106164..106166)
/locus_tag="CGSHiEE_00540"
/note="motif II; other site"
/db_xref="CDD:119389"
gene 106624..107001
/locus_tag="CGSHiEE_00545"
/db_xref="GeneID:5224869"
CDS 106624..107001
/locus_tag="CGSHiEE_00545"
/note="COG0637 Predicted phosphatase/phosphohexomutase"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289986.1"
/db_xref="GI:148825233"
/db_xref="GeneID:5224869"
/translation="MRLFKQLERWKIRKQINQSIIDVIFRLRARLANYWQADVNTPQV
DFMLLHIACSLGRIERGGCVSPLYSEMLEEIQSAVIFPQVLAIHQDLLKLMPFSIPEA
EQTYFLVNIHSLVLEQKQLKPLK"
gene 107141..107752
/gene="gidB"
/locus_tag="CGSHiEE_00550"
/db_xref="GeneID:5224870"
CDS 107141..107752
/gene="gidB"
/locus_tag="CGSHiEE_00550"
/note="glucose-inhibited division protein B; SAM-dependent
methyltransferase; methylates the N7 position of guanosine
in position 527 of 16S rRNA"
/codon_start=1
/transl_table=11
/product="16S rRNA methyltransferase GidB"
/protein_id="YP_001289987.1"
/db_xref="GI:148825234"
/db_xref="GeneID:5224870"
/translation="MKAKLVSLLAQANIKISDQQIQQLIDLVNLLNKWNKAYNLTSVR
DPQEMLVKHILDSLVVSPYLQGDRFIDVGTGPGLPGLPLAIINPSKQFVLLDSLGKRI
SFIRNAIRELRLTNATPVLSRVEEYQPEDKFDGVLSRAFASLKDMTDWCYHLPKENGY
FYALKGIYQEDEINELNKKYTIQKVIELSVPELIGERHLIVLR"
misc_feature 107237..107749
/gene="gidB"
/locus_tag="CGSHiEE_00550"
/note="16S rRNA methyltransferase GidB; Reviewed; Region:
gidB; PRK00107"
/db_xref="CDD:178868"
gene 107871..108245
/locus_tag="CGSHiEE_00555"
/db_xref="GeneID:5224871"
CDS 107871..108245
/locus_tag="CGSHiEE_00555"
/EC_number="3.6.3.14"
/note="Produces ATP from ADP in the presence of a proton
gradient across the membrane. Subunit I associates with
the membrane and may be involved with cation
translocation"
/codon_start=1
/transl_table=11
/product="F0F1 ATP synthase subunit I"
/protein_id="YP_001289988.1"
/db_xref="GI:148825235"
/db_xref="GeneID:5224871"
/translation="MSRIVQQAKVQYQKAIFIEIVIMLLLACFFALWQMKSAFDFLFG
FLSALIPFGVFVYVVFYRKQHLATKLTALYKGEAIKFVLTIVFISISFKYFSVTNFII
FFSGFFIALMLNNLVPFLLRRI"
misc_feature 107871..108242
/locus_tag="CGSHiEE_00555"
/note="F0F1 ATP synthase subunit I; Validated; Region:
PRK06099"
/db_xref="CDD:168392"
gene 108273..109061
/locus_tag="CGSHiEE_00560"
/db_xref="GeneID:5224872"
CDS 108273..109061
/locus_tag="CGSHiEE_00560"
/EC_number="3.6.3.14"
/note="Produces ATP from ADP in the presence of a proton
gradient across the membrane. Subunit A is part of the
membrane proton channel F0"
/codon_start=1
/transl_table=11
/product="F0F1 ATP synthase subunit A"
/protein_id="YP_001289989.1"
/db_xref="GI:148825236"
/db_xref="GeneID:5224872"
/translation="MFGQTTSEYISHHLSFLKTGDGFWNVHIDTLFFSILAAVIFLFV
FSRVGKKATTGVPGKMQCLVEIVVEWVNGIVKENFHGPRNVVAPLALTIFCWVFIMNA
IDLIPVDFLPQFAGLFGIHYLRAVPTADISATLGMSICVFFLILFYTIKSKGFKGLVK
EYTLHPFNHWAFIPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYSANMA
IAALGIPLHLAWAIFHILVITLQAFIFMMLTVVYLSIAYNKADH"
misc_feature 108300..109052
/locus_tag="CGSHiEE_00560"
/note="F0F1 ATP synthase subunit A; Validated; Region:
PRK05815"
/db_xref="CDD:180273"
gene 109117..109371
/locus_tag="CGSHiEE_00565"
/db_xref="GeneID:5224862"
CDS 109117..109371
/locus_tag="CGSHiEE_00565"
/EC_number="3.6.3.14"
/note="Produces ATP from ADP in the presence of a proton
gradient across the membrane. Subunit C is part of the
membrane proton channel F0"
/codon_start=1
/transl_table=11
/product="F0F1 ATP synthase subunit C"
/protein_id="YP_001289990.1"
/db_xref="GI:148825237"
/db_xref="GeneID:5224862"
/translation="METVITATIIGASILLAFAALGTAIGFAILGGKFLESSARQPEL
ASSLQTKMFIVAGLLDAIAMIAVGISLLFIFANPFIGLLH"
misc_feature 109117..109350
/locus_tag="CGSHiEE_00565"
/note="F0F1 ATP synthase subunit C; Validated; Region:
PRK06876"
/db_xref="CDD:180739"
gene 109421..109891
/locus_tag="CGSHiEE_00570"
/db_xref="GeneID:5224863"
CDS 109421..109891
/locus_tag="CGSHiEE_00570"
/EC_number="3.6.3.14"
/note="Produces ATP from ADP in the presence of a proton
gradient across the membrane. Subunit B is part of the
membrane proton channel."
/codon_start=1
/transl_table=11
/product="F0F1 ATP synthase subunit B"
/protein_id="YP_001289991.1"
/db_xref="GI:148825238"
/db_xref="GeneID:5224863"
/translation="MNLNATLIGQLIAFALFVWFCMKFVWPPIINAIETRQSQIANAL
ASAEAAKKEQADTKNLVEQELSAAKVQAQDILDAANKRRNEVLDEVKAEAEELKAKII
AQGYAEVEAERKRVQEELRLKVASLAVAGAEKIVGRSIDEAANNDIIDKLVAEL"
misc_feature 109421..109888
/locus_tag="CGSHiEE_00570"
/note="F0F1 ATP synthase subunit B; Validated; Region:
PRK05759"
/db_xref="CDD:180240"
misc_feature 109427..109888
/locus_tag="CGSHiEE_00570"
/note="F0F1-type ATP synthase, subunit b [Energy
production and conversion]; Region: AtpF; COG0711"
/db_xref="CDD:31055"
gene 109904..110437
/locus_tag="CGSHiEE_00575"
/db_xref="GeneID:5224864"
CDS 109904..110437
/locus_tag="CGSHiEE_00575"
/EC_number="3.6.3.14"
/note="Produces ATP from ADP in the presence of a proton
gradient across the membrane; the delta subunit is part of
the catalytic core of the ATP synthase complex"
/codon_start=1
/transl_table=11
/product="F0F1 ATP synthase subunit delta"
/protein_id="YP_001289992.1"
/db_xref="GI:148825239"
/db_xref="GeneID:5224864"
/translation="MSELTTIARPYAKAAFDFAIEQSAVEKWTEMLGFAAAVAEDETV
KAYLSSSLSAQKLADTVISICGEQLDQYGQNLIRLMAENKRLSAIPAVFEEFKHHVEE
HQAIAEVEVTSAQPLNATQIEKIAAAMEKRLARKVKLNCNVDNALIAGVIIRTEDFVI
DGSSRGQLTRLANELQL"
misc_feature 109904..110431
/locus_tag="CGSHiEE_00575"
/note="F0F1 ATP synthase subunit delta; Validated; Region:
PRK05758"
/db_xref="CDD:180239"
misc_feature 109922..110428
/locus_tag="CGSHiEE_00575"
/note="ATP synthase delta (OSCP) subunit; Region: OSCP;
pfam00213"
/db_xref="CDD:189453"
gene 110450..111991
/locus_tag="CGSHiEE_00580"
/db_xref="GeneID:5224865"
CDS 110450..111991
/locus_tag="CGSHiEE_00580"
/EC_number="3.6.3.14"
/note="produces ATP from ADP in the presence of a proton
gradient across the membrane; the alpha chain is a
catalytic subunit"
/codon_start=1
/transl_table=11
/product="F0F1 ATP synthase subunit alpha"
/protein_id="YP_001289993.1"
/db_xref="GI:148825240"
/db_xref="GeneID:5224865"
/translation="MQLNSTEISELIKKRIAQFDVVSEARNTGTIVSVSDGIIRIHGL
SDVMQGEMIALPGNRYAMALNLERDSVGAVVMGPYADLAEGMEVQCTGRILEVPVGRG
LLGRVVNTLGQPIDGKGEIENDGFSPVEVIAPGVIDRRSVDQPVQTGYKAVDSMVPIG
RGQRELIIGDRQTGKTALAIDAIINQRNSGIKCIYVAIGQKASTIANVVRKLEEHGAL
ANTIVVAASASESAALQYLAPYAGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLL
LRRPPGREAYPGDVFYLHSRLLERASRVNEDYVEKFTKGEVKGKTGSLTALPIIETQA
GDVSAFVPTNVISITDGQIFLESNLFNSGIRPAVNPGISVSRVGGSAQTKVIKKLAGG
IRTALAQYRELAAFAQFASDLDDATRKQLSHGEKVTELLKQKQFAPLSVAEQAVVLFA
VEFGYLDDVELSKIASFETALLDYSNRNHAEFMQELNKTGNYNDEIKDTLKGILDSFK
ANSAW"
misc_feature 110450..111979
/locus_tag="CGSHiEE_00580"
/note="F0F1 ATP synthase subunit alpha; Validated; Region:
PRK09281"
/db_xref="CDD:181753"
misc_feature 110525..110725
/locus_tag="CGSHiEE_00580"
/note="ATP synthase alpha/beta family, beta-barrel domain;
Region: ATP-synt_ab_N; pfam02874"
/db_xref="CDD:145823"
misc_feature 110786..111583
/locus_tag="CGSHiEE_00580"
/note="F1 ATP synthase alpha, central domain. The F-ATPase
is found in bacterial plasma membranes, mitochondrial
inner membranes and in chloroplast thylakoid membranes. It
has also been found in the archaea Methanosarcina barkeri.
It uses a proton gradient to...; Region: F1_ATPase_alpha;
cd01132"
/db_xref="CDD:29998"
misc_feature order(110792..110797,110843..110848,110852..110857,
110864..110866,110870..110872,110960..110965,
111050..111061,111065..111070,111077..111079,
111260..111265,111281..111289,111293..111298,
111311..111313,111323..111325,111332..111334,
111344..111346,111488..111490,111497..111499,
111530..111535,111542..111544,111575..111577)
/locus_tag="CGSHiEE_00580"
/note="beta subunit interaction interface [polypeptide
binding]; other site"
/db_xref="CDD:29998"
misc_feature 110954..110977
/locus_tag="CGSHiEE_00580"
/note="Walker A motif; other site"
/db_xref="CDD:29998"
misc_feature order(110960..110962,110972..110980,111032..111034,
111047..111049,111230..111235,111242..111244,
111440..111442,111488..111490,111527..111529,
111542..111547,111575..111577)
/locus_tag="CGSHiEE_00580"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:29998"
misc_feature 111218..111232
/locus_tag="CGSHiEE_00580"
/note="Walker B motif; other site"
/db_xref="CDD:29998"
misc_feature 111608..111877
/locus_tag="CGSHiEE_00580"
/note="ATP synthase alpha/beta chain, C terminal domain;
Region: ATP-synt_ab_C; pfam00306"
/db_xref="CDD:144044"
gene 112007..112876
/locus_tag="CGSHiEE_00585"
/db_xref="GeneID:5224866"
CDS 112007..112876
/locus_tag="CGSHiEE_00585"
/EC_number="3.6.3.14"
/note="Produces ATP from ADP in the presence of a proton
gradient across the membrane. The gamma chain is a
regulatory subunit"
/codon_start=1
/transl_table=11
/product="F0F1 ATP synthase subunit gamma"
/protein_id="YP_001289994.1"
/db_xref="GI:148825241"
/db_xref="GeneID:5224866"
/translation="MAGAKEIKTKIASVQSTQKITKAMEMVATSKMRKTQDRMAASRP
YSETIRNVISHVSKASIGYKHPFLVEREVKKIGILVISTDRGMCGGLNVNLFKTTLNQ
IKNWKEQNISTDLGLIGSKGISFFRSFGFNIKGQLSGLGDTPALEELIGVANTMFDAY
RNGEIDAIYIAYNKFVNTMSQKPVVQQLVPLPESKDDHLNERQQTWDYLYEPEPKALL
DSLLVRYLESQIYQAVVDNVASEQAARMVAMKAATDNAGNLINDLRLVYNKARQASIT
NELNEIVAGAAAI"
misc_feature 112007..112873
/locus_tag="CGSHiEE_00585"
/note="F0F1 ATP synthase subunit gamma; Validated; Region:
PRK05621"
/db_xref="CDD:180168"
misc_feature 112007..112873
/locus_tag="CGSHiEE_00585"
/note="F0F1 ATP synthase subunit gamma; Provisional;
Region: PRK13422"
/db_xref="CDD:184046"
gene 112893..114266
/locus_tag="CGSHiEE_00590"
/db_xref="GeneID:5224851"
CDS 112893..114266
/locus_tag="CGSHiEE_00590"
/EC_number="3.6.3.14"
/note="Produces ATP from ADP in the presence of a proton
gradient across the membrane. The beta chain is a
regulatory subunit"
/codon_start=1
/transl_table=11
/product="F0F1 ATP synthase subunit beta"
/protein_id="YP_001289995.1"
/db_xref="GI:148825242"
/db_xref="GeneID:5224851"
/translation="MSAGKIVQIIGAVIDVEFPQDAVPKVYDALKVESGLTLEVQQQL
GGGVVRCIALGTSDGLKRGLKVENTNNPIQVPVGTKTLGRIMNVLGEPIDEQGAIGEE
ERWAIHRSAPSYEEQSNSTELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMEL
IRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVSLVYGQMNEPPGNRLRVA
LTGLTMAEKFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVL
QERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDSTVVLSRQIASLGIYPAVDP
LDSTSRQLDPLVVGQEHYDVARGVQGILQRYKELKDIIAILGMDELSEEDKLVVARAR
KIERFLSQPFFVAEVFTGSPGKYVTLKDTIRGFKGILEGEYDHIPEQAFYMVGSIDEV
LEKAKNM"
misc_feature 112893..114263
/locus_tag="CGSHiEE_00590"
/note="F0F1 ATP synthase subunit beta; Validated; Region:
PRK09280"
/db_xref="CDD:181752"
misc_feature 112908..113102
/locus_tag="CGSHiEE_00590"
/note="ATP synthase alpha/beta family, beta-barrel domain;
Region: ATP-synt_ab_N; pfam02874"
/db_xref="CDD:145823"
misc_feature 113106..113924
/locus_tag="CGSHiEE_00590"
/note="F1 ATP synthase beta subunit, nucleotide-binding
domain. The F-ATPase is found in bacterial plasma
membranes, mitochondrial inner membranes and in
chloroplast thylakoid membranes. It has also been found in
the archaea Methanosarcina barkeri. It uses a...; Region:
F1-ATPase_beta; cd01133"
/db_xref="CDD:29999"
misc_feature order(113175..113177,113226..113228,113232..113237,
113241..113243,113247..113249,113430..113438,
113445..113447,113511..113519,113532..113534,
113622..113624,113631..113633,113643..113645,
113661..113669,113673..113678,113691..113693,
113703..113705,113724..113726,113775..113777,
113784..113789,113799..113801,113820..113822,
113826..113834,113865..113870,113895..113900,
113904..113906,113910..113912)
/locus_tag="CGSHiEE_00590"
/note="alpha subunit interaction interface [polypeptide
binding]; other site"
/db_xref="CDD:29999"
misc_feature 113334..113354
/locus_tag="CGSHiEE_00590"
/note="Walker A motif; other site"
/db_xref="CDD:29999"
misc_feature order(113340..113342,113349..113357,113427..113432,
113439..113441,113610..113612,113622..113624,
113874..113879)
/locus_tag="CGSHiEE_00590"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:29999"
misc_feature 113598..113612
/locus_tag="CGSHiEE_00590"
/note="Walker B motif; other site"
/db_xref="CDD:29999"
misc_feature order(113868..113870,113874..113876,113892..113897)
/locus_tag="CGSHiEE_00590"
/note="inhibitor binding site; inhibition site"
/db_xref="CDD:29999"
misc_feature 113946..114263
/locus_tag="CGSHiEE_00590"
/note="ATP synthase alpha/beta chain, C terminal domain;
Region: ATP-synt_ab_C; pfam00306"
/db_xref="CDD:144044"
gene 114296..114724
/gene="atpC"
/locus_tag="CGSHiEE_00595"
/db_xref="GeneID:5224852"
CDS 114296..114724
/gene="atpC"
/locus_tag="CGSHiEE_00595"
/EC_number="3.6.3.14"
/note="part of catalytic core of ATP synthase;
alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in
producing ATP from ADP in the presence of the proton
motive force across the membrane"
/codon_start=1
/transl_table=11
/product="F0F1 ATP synthase subunit epsilon"
/protein_id="YP_001289996.1"
/db_xref="GI:148825243"
/db_xref="GeneID:5224852"
/translation="MATFNLTIVSAEQKIFEGEVKQIQVTGVEGELGILPGHTPLLTA
IKPGIVKFTLKDGNEEVIYVSGGFLEVQPNIVTVLADIAIRGSELDADRIHEAKRKAE
ENIVSRGSDADHDLLVAKLSKELAKLRAYELTEKLLKTRR"
misc_feature 114296..114697
/gene="atpC"
/locus_tag="CGSHiEE_00595"
/note="F0F1 ATP synthase subunit epsilon; Validated;
Region: atpC; PRK00571"
/db_xref="CDD:179070"
misc_feature 114305..114544
/gene="atpC"
/locus_tag="CGSHiEE_00595"
/note="ATP synthase, Delta/Epsilon chain, beta-sandwich
domain; Region: ATP-synt_DE_N; pfam02823"
/db_xref="CDD:202416"
gene complement(114910..116112)
/locus_tag="CGSHiEE_00600"
/db_xref="GeneID:5224853"
CDS complement(114910..116112)
/locus_tag="CGSHiEE_00600"
/codon_start=1
/transl_table=11
/product="tyrosine-specific transport protein 1"
/protein_id="YP_001289997.1"
/db_xref="GI:148825244"
/db_xref="GeneID:5224853"
/translation="MNKTVGSTLLVAGTMIGAGMLAMPLTSAGIGFGFTLILLLGLWA
LLTFSALLFVELYQTAESDAGIGTLAEQYFGKAGRIIATAVLIIFLYALIAAYISGGG
SLLKDLLPESFGDKVSVLLFTVIFGSFIVIGTHSVDKINRVLFFVMLAAFAVVLSLML
PEIKFDNLMATPIDKALIISASPVFFTAFGFHGSIPSLNKYLDGNVKALRFSILVGSA
ITLCAYILWQLSTHGLLTQNEFLQILKEDATLNGLVKATFAITGSNVIASAVKLFSTL
ALITSFLGVGLGLLECIEDLLKRSFNVTAGRISLGLLTFIPPLVFALFYPEGFILALG
YAGQMFAFYAVVLPVSLVWKARRIHRNLPYKVWGGNLTLIIVLVLGVIITSIPFAIRA
GYLPFVVG"
misc_feature complement(115012..116109)
/locus_tag="CGSHiEE_00600"
/note="Tryptophan/tyrosine permease family; Region:
Trp_Tyr_perm; pfam03222"
/db_xref="CDD:112053"
misc_feature complement(115012..116097)
/locus_tag="CGSHiEE_00600"
/note="aromatic amino acid transport protein; Region:
araaP; TIGR00837"
/db_xref="CDD:162061"
gene complement(116142..116294)
/locus_tag="CGSHiEE_00605"
/db_xref="GeneID:5224854"
CDS complement(116142..116294)
/locus_tag="CGSHiEE_00605"
/note="COG0814 Amino acid permeases"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001289998.1"
/db_xref="GI:148825245"
/db_xref="GeneID:5224854"
/translation="MVIKCIDKQQNLGNIILFLLLKQQYSKEDSKKFTIYKFYLQTVN
YTIQLS"
misc_feature complement(116376..117040)
/note="potential frameshift: common BLAST hit:
gi|68249077|ref|YP_248189.1| histidine biosynthesis
bifunctional protein HisIE [Haemophilus]"
gene complement(117040..117816)
/locus_tag="CGSHiEE_00620"
/db_xref="GeneID:5224855"
CDS complement(117040..117816)
/locus_tag="CGSHiEE_00620"
/note="catalyzes the conversion of
5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-
1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine
to imidazole-glycerol phosphate,
5-aminoimidazol-4-carboxamideribonucleotide and glutamate;
the HisF subunit acts as a cyclase"
/codon_start=1
/transl_table=11
/product="imidazole glycerol phosphate synthase subunit
HisF"
/protein_id="YP_001289999.1"
/db_xref="GI:148825246"
/db_xref="GeneID:5224855"
/translation="MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAQHYAQEGA
DELVFYDITASSDGRTVDKSWVERIAQVIDIPFCVAGGIKTIEDAEKLFAFGADKISI
NSPALADPTLISRLADRFGVQAIVVGIDSWFEQETGKYWVNQYTGDETRTRQTHWQLL
DWVKEVQQCGAGEIVLNMMNQDGLRNGYDLAQLKLVRGVCRVPLIASGGAGKMVHFRD
AFIEAKVDGALAASVFHKQIIEIGELKSYLVKSAIEIRSE"
misc_feature complement(117073..117807)
/locus_tag="CGSHiEE_00620"
/note="The cyclase subunit of imidazoleglycerol phosphate
synthase (HisF). Imidazole glycerol phosphate synthase
(IGPS) catalyzes the fifth step of histidine biosynthesis,
the formation of the imidazole ring. IGPS converts
N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731"
/db_xref="CDD:73393"
misc_feature complement(117100..117804)
/locus_tag="CGSHiEE_00620"
/note="Histidine biosynthesis protein; Region:
His_biosynth; pfam00977"
/db_xref="CDD:201535"
misc_feature complement(order(117121..117126,117190..117198,
117268..117273,117286..117288,117367..117369,
117427..117429,117433..117435,117505..117510,
117571..117573,117667..117669,117760..117762))
/locus_tag="CGSHiEE_00620"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:73393"
misc_feature complement(order(117139..117141,117214..117216,
117298..117300,117448..117450,117520..117525,
117532..117534,117589..117591,117595..117597,
117604..117606,117616..117618,117682..117684,
117697..117699))
/locus_tag="CGSHiEE_00620"
/note="glutamase interaction surface [polypeptide
binding]; other site"
/db_xref="CDD:73393"
gene complement(117798..118547)
/locus_tag="CGSHiEE_00625"
/db_xref="GeneID:5224767"
CDS complement(117798..118547)
/locus_tag="CGSHiEE_00625"
/EC_number="5.3.1.16"
/note="catalyzes the formation of
5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l-
(5-phosphoribosyl)imidazole-4-carboxamide from
1-(5-phosphoribosyl)-5-[(5-
phosphoribosylamino)methylideneamino]
imidazole-4-carboxamide"
/codon_start=1
/transl_table=11
/product="1-(5-phosphoribosyl)-5-[(5-
phosphoribosylamino)methylideneamino]
imidazole-4-carboxamide isomerase"
/protein_id="YP_001290000.1"
/db_xref="GI:148825247"
/db_xref="GeneID:5224767"
/translation="MKQSIIIPALDLINGQVVRLHQGDYAKQTTYSDNPIKQFDNYVR
QGAKQLHLVDLTGAKNPQSRQTALIGKIVEATQCKVQVGGGIRTEQDVADLLAVGANR
VVIGSTAVTHRSMVKNWFIKYGAEKFVLALDVNINASGQKIVAISGWQEESGVLLETL
IEDFQTVGLQQVLCTDISRDGTLTGSNIGLYQEICEKYPPIQFQSSGGIGSLADIEAL
KGTGVSGVIVGRALLEGKFTLSEAIKCWQNG"
misc_feature complement(117801..118535)
/locus_tag="CGSHiEE_00625"
/note="Phosphoribosylformimino-5-aminoimidazole
carboxamide ribonucleotide (ProFAR) isomerase [Amino acid
transport and metabolism]; Region: HisA; COG0106"
/db_xref="CDD:30455"
misc_feature complement(117816..118535)
/locus_tag="CGSHiEE_00625"
/note="HisA. Phosphoribosylformimino-5-aminoimidazole
carboxamide ribonucleotide (ProFAR) isomerase catalyzes
the fourth step in histidine biosynthesis, an
isomerisation of the aminoaldose moiety of ProFAR to the
aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA;
cd04732"
/db_xref="CDD:73394"
misc_feature complement(order(118149..118151,118395..118397,
118515..118517))
/locus_tag="CGSHiEE_00625"
/note="catalytic residues [active]"
/db_xref="CDD:73394"
gene complement(118583..119182)
/gene="hisH"
/locus_tag="CGSHiEE_00630"
/db_xref="GeneID:5224768"
CDS complement(118583..119182)
/gene="hisH"
/locus_tag="CGSHiEE_00630"
/EC_number="5.3.1.16"
/note="with HisF IGPS catalyzes the conversion of
phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide
ribonucleotide phosphate and glutamine to
imidazole-glycerol phosphate,
5-aminoimidazol-4-carboxamide ribonucleotide, and
glutamate in histidine biosynthesis; the HisH subunit
provides the glutamine amidotransferase activity that
produces the ammonia necessary to HisF for the synthesis
of imidazole-glycerol phosphate and
5-aminoimidazol-4-carboxamide ribonucleotide"
/codon_start=1
/transl_table=11
/product="imidazole glycerol phosphate synthase subunit
HisH"
/protein_id="YP_001290001.1"
/db_xref="GI:148825248"
/db_xref="GeneID:5224768"
/translation="MTNITIIDTGCANLSSVKFAFDRLGYNTEITFDLNKIKSADKLI
LPGVGTANAAMYNLQERQLIETIQNLTQPVLGICLGMQLMTEFSEEGNVPTLNLISGK
TNRIPDTGLPLPQMGWNRVQFVKNCPLFDGIVQNSHFYFVHSYAVSPNEHSVAISNYG
VNFSAAIAKENFYGVQFHPERSGKNGALLLKNFVEKVPF"
misc_feature complement(118598..119176)
/gene="hisH"
/locus_tag="CGSHiEE_00630"
/note="imidazole glycerol phosphate synthase subunit HisH;
Provisional; Region: hisH; PRK13170"
/db_xref="CDD:183877"
misc_feature complement(118601..119173)
/gene="hisH"
/locus_tag="CGSHiEE_00630"
/note="Type 1 glutamine amidotransferase (GATase1) domain
found in imidazole glycerol phosphate synthase (IGPS);
Region: GATase1_IGP_Synthase; cd01748"
/db_xref="CDD:153219"
misc_feature complement(order(118643..118645,118649..118651,
118943..118957,119036..119059))
/gene="hisH"
/locus_tag="CGSHiEE_00630"
/note="putative active site [active]"
/db_xref="CDD:153219"
misc_feature complement(119036..119059)
/gene="hisH"
/locus_tag="CGSHiEE_00630"
/note="oxyanion strand; other site"
/db_xref="CDD:153219"
misc_feature complement(order(118643..118645,118649..118651,
118949..118951))
/gene="hisH"
/locus_tag="CGSHiEE_00630"
/note="catalytic triad [active]"
/db_xref="CDD:153219"
gene complement(119248..120336)
/locus_tag="CGSHiEE_00635"
/db_xref="GeneID:5224769"
CDS complement(119248..120336)
/locus_tag="CGSHiEE_00635"
/EC_number="4.2.1.19"
/EC_number="3.1.3.15"
/note="catalyzes the formation of
3-(imidazol-4-yl)-2-oxopropyl phosphate from
D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and
histidinol from histidinol phosphate"
/codon_start=1
/transl_table=11
/product="imidazole glycerol-phosphate
dehydratase/histidinol phosphatase"
/protein_id="YP_001290002.1"
/db_xref="GI:148825249"
/db_xref="GeneID:5224769"
/translation="MQPTLFIDRDGTLIDEPKTDFQIDSLEKLKLEPKVIPALLRLKA
KYRFVIVSNQDGLGTDAFPQTNFDKPHNVMMALFESQGITFDEVLICPHKPEENCLCR
KPKIKLLDHYIRKNLFDIDRSFVIGDRETDMQLAENLGIRAIQYDPQKMNWDLIAEKL
LGETVTNCGKRPPRFAEVIRQTKETDIKVQVWLDEAGVNEIKTGVGFFDHMLDQIATH
GGFRMNVQCKGDLWIDEHHTVEDTALALGQALKQAIGDKRGIARFGFVLPMDECKAEC
ALDLSGRPWIKFNACFKRDKVGDFSTELTEHFFQSLAFSMLATLHLNVTGNNDHHKIE
SLFKAFGRTLRQAIRIEGNEMPSSKGVL"
misc_feature complement(119251..120336)
/locus_tag="CGSHiEE_00635"
/note="imidazole glycerol-phosphate dehydratase/histidinol
phosphatase; Provisional; Region: PRK05446"
/db_xref="CDD:180088"
misc_feature complement(119905..120324)
/locus_tag="CGSHiEE_00635"
/note="Haloacid dehalogenase-like hydrolases. The haloacid
dehalogenase-like (HAD) superfamily includes L-2-haloacid
dehalogenase, epoxide hydrolase, phosphoserine
phosphatase, phosphomannomutase, phosphoglycolate
phosphatase, P-type ATPase, and many others; Region:
HAD_like; cd01427"
/db_xref="CDD:119389"
misc_feature complement(order(120178..120183,120307..120315))
/locus_tag="CGSHiEE_00635"
/note="active site"
/db_xref="CDD:119389"
misc_feature complement(120298..120315)
/locus_tag="CGSHiEE_00635"
/note="motif I; other site"
/db_xref="CDD:119389"
misc_feature complement(120181..120183)
/locus_tag="CGSHiEE_00635"
/note="motif II; other site"
/db_xref="CDD:119389"
misc_feature complement(119251..119811)
/locus_tag="CGSHiEE_00635"
/note="Imidazoleglycerol-phosphate dehydratase; Region:
IGPD; cd07914"
/db_xref="CDD:153419"
misc_feature complement(order(119335..119337,119344..119349,
119416..119418,119488..119490,119527..119532,
119551..119553,119617..119619,119626..119631,
119683..119688,119695..119697,119707..119709,
119785..119787))
/locus_tag="CGSHiEE_00635"
/note="putative active site pocket [active]"
/db_xref="CDD:153419"
misc_feature complement(order(119344..119358,119416..119421,
119428..119430,119434..119436,119443..119457,
119626..119631,119635..119643,119707..119709,
119716..119721))
/locus_tag="CGSHiEE_00635"
/note="4-fold oligomerization interface [polypeptide
binding]; other site"
/db_xref="CDD:153419"
misc_feature complement(order(119335..119337,119344..119349,
119416..119418,119617..119619,119626..119631,
119707..119709))
/locus_tag="CGSHiEE_00635"
/note="metal binding residues [ion binding]; metal-binding
site"
/db_xref="CDD:153419"
misc_feature complement(order(119284..119286,119302..119304,
119311..119313,119368..119370,119374..119376,
119380..119382,119482..119484,119488..119490,
119500..119508,119518..119523,119527..119535,
119539..119544,119548..119550,119554..119556))
/locus_tag="CGSHiEE_00635"
/note="3-fold/trimer interface [polypeptide binding];
other site"
/db_xref="CDD:153419"
gene complement(120448..121506)
/locus_tag="CGSHiEE_00640"
/db_xref="GeneID:5224770"
CDS complement(120448..121506)
/locus_tag="CGSHiEE_00640"
/EC_number="2.6.1.9"
/note="catalyzes the formation of L-histidinol phosphate
from imidazole-acetol phosphate and glutamate in histidine
biosynthesis"
/codon_start=1
/transl_table=11
/product="histidinol-phosphate aminotransferase"
/protein_id="YP_001290003.1"
/db_xref="GI:148825250"
/db_xref="GeneID:5224770"
/translation="MTITTLSRQNIQALTPYQSARKLGGNGTIWLNANEYPTSPKFQL
SGKDLNRYPEPQPQRVVQAYANYAGVSTENVLVTRGGDEGIELIIHTFCEPKQDAILF
CPPTYGMYAVSAETAGVLSKTVPLTDDFQLNLPEIKNHLNDVKVVFVCSPNNPTGNLL
KQSDILDLLQITAGKAIVVVDEAYIEFCPEASVINLLKNYPHLAIIRTLSKAFALAGL
RCGFVLANPELIDILSKVIAPYPIPVPSADLAEQALRPANIATVQALTQELLSNRQWL
AKALLVLHQVEKVYESEANYLLIKCQNGQAVFKALWEQGIILRDQNKTLHLQNCIRIT
VGTRNECEKVVEAIKEVK"
misc_feature complement(120460..121485)
/locus_tag="CGSHiEE_00640"
/note="histidinol-phosphate aminotransferase; Region:
hisC; TIGR01141"
/db_xref="CDD:162223"
misc_feature complement(120457..121422)
/locus_tag="CGSHiEE_00640"
/note="Aspartate aminotransferase family. This family
belongs to pyridoxal phosphate (PLP)-dependent aspartate
aminotransferase superfamily (fold I). Pyridoxal phosphate
combines with an alpha-amino acid to form a compound
called a Schiff base or aldimine...; Region: AAT_like;
cd00609"
/db_xref="CDD:99734"
misc_feature complement(order(120850..120852,120874..120879,
120883..120885,120955..120957,121045..121047,
121186..121188,121261..121269))
/locus_tag="CGSHiEE_00640"
/note="pyridoxal 5'-phosphate binding site [chemical
binding]; other site"
/db_xref="CDD:99734"
misc_feature complement(order(120760..120762,120769..120771,
120850..120858,120976..120978,121156..121158,
121258..121260))
/locus_tag="CGSHiEE_00640"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:99734"
misc_feature complement(120874..120876)
/locus_tag="CGSHiEE_00640"
/note="catalytic residue [active]"
/db_xref="CDD:99734"
gene complement(121620..122903)
/gene="hisD"
/locus_tag="CGSHiEE_00645"
/db_xref="GeneID:5224771"
CDS complement(121620..122903)
/gene="hisD"
/locus_tag="CGSHiEE_00645"
/EC_number="1.1.1.23"
/note="catalyzes the oxidation of L-histidinol to
L-histidinaldehyde and then to L-histidine in histidine
biosynthesis; functions as a dimer"
/codon_start=1
/transl_table=11
/product="histidinol dehydrogenase"
/protein_id="YP_001290004.1"
/db_xref="GI:148825251"
/db_xref="GeneID:5224771"
/translation="MQTIIWNHLSETEKRKVIMRPVQQNGKNIQQAVNAIRENVAYNG
DRALFELCEKFDGVKLDKLIVSADEIQAASSRISVKLRNAIEQAKTNIEAFHKAQQNQ
EIDLEIQEGVRCQVVTRPISCVGLYIPGGSAPLFSTVLMLAIPAKIAGCKKIVLCSPP
PISDEILYTAHLCGVETIYSIGGAQAVFAMAQGTESVAKVDKIFGPGNAFVTEAKRQV
AQNSTAIDMPAGPSEVLVIADESADPEFVASDLLSQAEHGADSQVILVATCETLAKET
ALAIERQLALLPRAETARKALNHSRIFIAESLEQTVEISNEYAPEHLIVQTKNARKLL
PYLDNAGSIFLGAYSPESMGDYASGTNHVLPTYGYTKTYSSLGLADFSKRMTVQELTP
KGFKNLAETVEVMAEAEQLAAHKMAVSVRLAKLNI"
misc_feature complement(121638..122864)
/gene="hisD"
/locus_tag="CGSHiEE_00645"
/note="Histidinol dehydrogenase; Region: Histidinol_dh;
pfam00815"
/db_xref="CDD:109855"
misc_feature complement(121662..122819)
/gene="hisD"
/locus_tag="CGSHiEE_00645"
/note="Histidinol dehydrogenase, HisD, E.C 1.1.1.23.
Histidinol dehydrogenase catalyzes the last two steps in
the L-histidine biosynthesis pathway, which is conserved
in bacteria, archaea, fungi, and plants. These last two
steps are (i) the NAD-dependent...; Region: Histidinol_dh;
cd06572"
/db_xref="CDD:119329"
misc_feature complement(order(122133..122135,122271..122276,
122280..122288,122349..122351,122355..122360,
122427..122429,122490..122492,122514..122519,
122523..122525,122739..122741))
/gene="hisD"
/locus_tag="CGSHiEE_00645"
/note="NAD binding site [chemical binding]; other site"
/db_xref="CDD:119329"
misc_feature complement(order(121662..121682,121686..121691,
121734..121757,121764..121769,121773..121787,
121791..121796,121824..121826,121830..121832,
121836..121850,121854..121859,121863..121865,
121869..121895,121899..121904,121911..121913,
121926..121928,122133..122138,122142..122150,
122154..122159,122166..122171,122241..122243,
122256..122258,122301..122303,122493..122507,
122541..122543,122547..122549,122556..122570,
122580..122582,122586..122588,122607..122612,
122619..122624,122631..122636,122643..122645,
122649..122654,122661..122666))
/gene="hisD"
/locus_tag="CGSHiEE_00645"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:119329"
misc_feature complement(order(121662..121664,121671..121673,
121677..121679,121818..121820,121836..121841,
121851..121853,121938..121943,122133..122135,
122208..122210,122493..122495,122499..122501))
/gene="hisD"
/locus_tag="CGSHiEE_00645"
/note="product binding site; other site"
/db_xref="CDD:119329"
misc_feature complement(order(121662..121664,121671..121673,
121677..121679,121818..121820,121836..121841,
121851..121853,121938..121943,122133..122135,
122142..122144,122208..122210,122493..122495))
/gene="hisD"
/locus_tag="CGSHiEE_00645"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:119329"
misc_feature complement(order(121662..121664,121839..121841,
122133..122135,122142..122144))
/gene="hisD"
/locus_tag="CGSHiEE_00645"
/note="zinc binding site [ion binding]; other site"
/db_xref="CDD:119329"
misc_feature complement(121938..121943)
/gene="hisD"
/locus_tag="CGSHiEE_00645"
/note="catalytic residues [active]"
/db_xref="CDD:119329"
gene complement(122996..123907)
/gene="hisG"
/locus_tag="CGSHiEE_00650"
/db_xref="GeneID:5224772"
CDS complement(122996..123907)
/gene="hisG"
/locus_tag="CGSHiEE_00650"
/EC_number="2.4.2.17"
/note="long form of enzyme; catalyzes the formation of
N'-5'-phosphoribosyl-ATP from phosphoribosyl
pyrophosphate; crucial role in histidine biosynthesis;
forms active dimers and inactive hexamers which is
dependent on concentration of substrates and inhibitors"
/codon_start=1
/transl_table=11
/product="ATP phosphoribosyltransferase"
/protein_id="YP_001290005.1"
/db_xref="GI:148825252"
/db_xref="GeneID:5224772"
/translation="MTNTTMQPNRLRIALQKKGRLSQDCAILLKQCGVKINWNEQRLI
AYAENLPIEILRVRDDDIPGLIFDGVVDLGIIGENVLEEEELGRRAANETVTYKKLRQ
LDFGDCRLSLAVDRDCHYENVKDLANRRIATSYPYLLKRYMNENGVSFKSCLLNGSVE
VAPSAGIAYAICDLVSSGATLEANGLKEVDVIYRSKACLIQRAEPLESTKQALVDKLL
TRIQGVQQAAESKYIMLHAPKEKLEKITALLPGVENPTILPLASDTTRVAMHVVSQEN
LFWETMEQLKEAGASSILVLPIEKMME"
misc_feature complement(122999..123883)
/gene="hisG"
/locus_tag="CGSHiEE_00650"
/note="ATP phosphoribosyltransferase; Reviewed; Region:
hisG; PRK00489"
/db_xref="CDD:179047"
misc_feature complement(123233..123739)
/gene="hisG"
/locus_tag="CGSHiEE_00650"
/note="ATP phosphoribosyltransferase; Region: HisG;
pfam01634"
/db_xref="CDD:110621"
misc_feature complement(123002..123292)
/gene="hisG"
/locus_tag="CGSHiEE_00650"
/note="ATP phosphoribosyltransferase, C-terminal domain;
Region: HisG_C-term; TIGR03455"
/db_xref="CDD:132496"
gene 124356..125219
/locus_tag="CGSHiEE_00655"
/db_xref="GeneID:5224722"
CDS 124356..125219
/locus_tag="CGSHiEE_00655"
/note="COG1561 Uncharacterized stress-induced protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290006.1"
/db_xref="GI:148825253"
/db_xref="GeneID:5224722"
/translation="MIYSMTAFARLEVKKDWGDAVWEIRSVNQRYLENFFRLPEQFRG
LENTLREKLRQSLTRGKIECSLRIETKKQTNAELNLNKDLANQVIQSLQWIKAQAGEG
EINLTDVLRYPGVVEAQEQDLDAISQDLLTAFDDLLTDFIAMRGREGEKLNDIIQQRL
DAIAVEADKVRSQMPAVLQWQRERLLQRFEDAQVNLDPQRVEQEMILLAQRVDVAEEL
DRLQMHVKETTNILKKGGAVGRKLDFMMQELNRESNTLASKSINADITASAVELKVLI
EQMREQIQNLE"
misc_feature 124356..125216
/locus_tag="CGSHiEE_00655"
/note="hypothetical protein; Provisional; Region:
PRK11820"
/db_xref="CDD:183325"
misc_feature 124359..124820
/locus_tag="CGSHiEE_00655"
/note="YicC-like family, N-terminal region; Region:
YicC_N; pfam03755"
/db_xref="CDD:146410"
misc_feature 124959..125216
/locus_tag="CGSHiEE_00655"
/note="Domain of unknown function (DUF1732); Region:
DUF1732; pfam08340"
/db_xref="CDD:149411"
gene 125229..126071
/locus_tag="CGSHiEE_00660"
/db_xref="GeneID:5224723"
CDS 125229..126071
/locus_tag="CGSHiEE_00660"
/note="COG0354 Predicted aminomethyltransferase related to
GcvT"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290007.1"
/db_xref="GI:148825254"
/db_xref="GeneID:5224723"
/translation="MSQFISLTQYQLIEVQGADAEKYLQGQLTSDVVRLASGATTLTA
HCDPKGKMNAIYRLFKVSSEQFFLLVKKDILPSGLDALKKYAVFSKVSFDLRDWQIIG
VIGEKCGKITPHFSLEIDEQRSILLNESELPVNFNGDEKIWEVADIQAGLPNLSPQTQ
NEFIPQALNLQAIEQAISFTKGCYIGQETVARAKYRGANKRAMFIFKAQTQQEAEIGS
EIEMQLEANWRKTGTITSAVNLDGVLWLQVVMNNDIDSEQQFRLPSNEILLERVQLPY
SITE"
misc_feature 125229..126068
/locus_tag="CGSHiEE_00660"
/note="Predicted aminomethyltransferase related to GcvT
[General function prediction only]; Region: COG0354"
/db_xref="CDD:30703"
misc_feature 125655..125852
/locus_tag="CGSHiEE_00660"
/note="folate-binding protein YgfZ; Region:
ygfZ_signature; TIGR03317"
/db_xref="CDD:163214"
misc_feature 125772..>125942
/locus_tag="CGSHiEE_00660"
/note="Glycine cleavage T-protein C-terminal barrel
domain; Region: GCV_T_C; pfam08669"
/db_xref="CDD:204020"
gene complement(126115..127347)
/locus_tag="CGSHiEE_00665"
/db_xref="GeneID:5224724"
CDS complement(126115..127347)
/locus_tag="CGSHiEE_00665"
/note="catalyzes the formation of 3-phosphonooxypyruvate
from 3-phospho-D-glycerate in serine biosynthesis; can
also reduce alpha ketoglutarate to form
2-hydroxyglutarate"
/codon_start=1
/transl_table=11
/product="D-3-phosphoglycerate dehydrogenase"
/protein_id="YP_001290008.1"
/db_xref="GI:148825255"
/db_xref="GeneID:5224724"
/translation="MTNKVSLDKSKIKFVLFEGVHQSALDTLHAAGYSNIDYYKKALD
GDELKEAIKDAHFIGLRSRTHLTAEMIEAAPKLIAVGCFCIGTNQVDLNAAKARGIPV
FNAPFSNTRSVAELVLGEILLLMRNVPQANAEVHRGVWNKSATGSHEVRGKKLGIIGY
GHIGSQLSIIAESLGMDVYFYDIENKLPLGNAKQVRSLEELLSSCDVVSLHVPELPST
KNLMNATRIAQLKQGAILINAARGTVVDIDALAQALKDGKIHGAAIDVFPVEPASINE
EFVSPLREFDNVILTPHIGGSTAEAQENIGFEVAGKFVKYSDNGSTLSSVNFPEVSLP
EHEGTKRLLHIHENRPGILNKLNQIFVEANLNIAAQYLQTDPKIGYVVVDVETNDASP
LLTKLKEIDGTIRARVLY"
misc_feature complement(126118..127344)
/locus_tag="CGSHiEE_00665"
/note="D-3-phosphoglycerate dehydrogenase; Provisional;
Region: PRK11790"
/db_xref="CDD:183316"
misc_feature complement(126463..126996)
/locus_tag="CGSHiEE_00665"
/note="D-isomer specific 2-hydroxyacid dehydrogenase, NAD
binding domain; Region: 2-Hacid_dh_C; pfam02826"
/db_xref="CDD:202418"
misc_feature complement(126121..126327)
/locus_tag="CGSHiEE_00665"
/note="C-terminal ACT (regulatory) domain of
D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi
and bacteria; Region: ACT_3PGDH; cd04901"
/db_xref="CDD:153173"
misc_feature complement(order(126250..126252,126304..126306,
126310..126312))
/locus_tag="CGSHiEE_00665"
/note="L-serine binding site [chemical binding]; other
site"
/db_xref="CDD:153173"
misc_feature complement(order(126226..126246,126250..126252,
126277..126279,126286..126291,126298..126300,
126304..126306))
/locus_tag="CGSHiEE_00665"
/note="ACT domain interface; other site"
/db_xref="CDD:153173"
gene complement(127377..128036)
/locus_tag="CGSHiEE_00670"
/db_xref="GeneID:5224725"
CDS complement(127377..128036)
/locus_tag="CGSHiEE_00670"
/EC_number="5.3.1.6"
/note="Catalyzes D-ribose 5-phosphate --> D-ribulose
5-phosphate in the nonoxidative branch of the pentose
phosphate pathway"
/codon_start=1
/transl_table=11
/product="ribose-5-phosphate isomerase A"
/protein_id="YP_001290009.1"
/db_xref="GI:148825256"
/db_xref="GeneID:5224725"
/translation="MDQLEMKKLAAQAALEYVKADTIVGVGSGSTVNCFIEALGTIKN
KIQGAVAASKASEELLRKQGIEVFNANDVSSLDIYVDGADEINPQKMMIKGGGAALTR
EKIVAALAKKFICIVDSSKQVDVLGSTFPLPVEVIPMARSQVGRKLVALGGAPEYREG
VVTDNGNVILDVHNFSILNPVEMEKELNNVAGVATNGIFALRGADVVIVGTPEGAKII
D"
misc_feature complement(127404..128021)
/locus_tag="CGSHiEE_00670"
/note="RPI_A: Ribose 5-phosphate isomerase type A (RPI_A)
subfamily; RPI catalyzes the reversible conversion of
ribose-5-phosphate to ribulose 5-phosphate, the first step
of the non-oxidative branch of the pentose phosphate
pathway. This reaction leads to the...; Region: RPI_A;
cd01398"
/db_xref="CDD:73164"
misc_feature complement(order(127533..127535,127545..127547,
127551..127553,127560..127565,127746..127751,
127830..127832,127836..127838,127863..127868,
127875..127877,127953..127955))
/locus_tag="CGSHiEE_00670"
/note="tetramer (dimer of dimers) interface [polypeptide
binding]; other site"
/db_xref="CDD:73164"
misc_feature complement(order(127674..127676,127728..127730,
127746..127757,127785..127787,127791..127796,
127944..127949,127953..127955))
/locus_tag="CGSHiEE_00670"
/note="active site"
/db_xref="CDD:73164"
misc_feature complement(order(127455..127457,127470..127475,
127599..127601,127608..127616,127620..127625,
127710..127712,127731..127733,127815..127817,
127827..127829))
/locus_tag="CGSHiEE_00670"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:73164"
gene complement(128170..129099)
/locus_tag="CGSHiEE_00675"
/db_xref="GeneID:5224726"
CDS complement(128170..129099)
/locus_tag="CGSHiEE_00675"
/note="COG0635 Coproporphyrinogen III oxidase and related
Fe-S oxidoreductases"
/codon_start=1
/transl_table=11
/product="coproporphyrinogen III oxidase"
/protein_id="YP_001290010.1"
/db_xref="GI:148825257"
/db_xref="GeneID:5224726"
/translation="MFSSESIAHLLKEIKKQIDFENNIEITLEANPSTVEAKRFKGYV
SAGITRISMGIQSFNDDKLRRLGRIHNAAEAKSAVNLAKVSGLKSFNLDLMHGLPNQT
LEEALDDLRQAIELSPPHISWYQLTIEPNTMFAYRPPKLPDDDALWDIFEQGHQLLTA
AGYQQYETSAYAKTGFQCKHNLNYWRFGDYLAIGCGAHGKLTFPNGEITRFSKTKPPK
GYLRGEYLYEEKNVPEIDRPFEFFMNRFRLLEAVPKQEFEDYTGLSQSAVKNQIDFAI
QQNYIVENADSWQITEHGKLFLNELLELFLTEE"
misc_feature complement(128215..129099)
/locus_tag="CGSHiEE_00675"
/note="HemN family oxidoreductase; Provisional; Region:
PRK05660"
/db_xref="CDD:180187"
misc_feature complement(128218..128406)
/locus_tag="CGSHiEE_00675"
/note="HemN C-terminal domain; Region: HemN_C; pfam06969"
/db_xref="CDD:203555"
gene complement(129440..131851)
/locus_tag="CGSHiEE_00680"
/db_xref="GeneID:5225262"
CDS complement(129440..131851)
/locus_tag="CGSHiEE_00680"
/note="COG0466 ATP-dependent Lon protease, bacterial type"
/codon_start=1
/transl_table=11
/product="ATP-dependent proteinase"
/protein_id="YP_001290011.1"
/db_xref="GI:148825258"
/db_xref="GeneID:5225262"
/translation="MAKNTQRTMPVLPLRDVVVFPYMVMPLFVGRAKSINALEEAMND
DKQLLLVSQREADLEEPTPEDLFDVGTIANIIQLLKLPDGTVKVLVEGQNRAKINNLE
DGEKYFSAKITPIETTYGNEKELVVAKSAVLSEFENYLTLNKKVPTDILNALQRIDDV
DRLADTMAAHLPVSIRHKQNALELANVQERLEYLLGMMESEADILQVEKRIRGRVKKQ
MEKSQRNYYLNEQIKAIRKEMDGGENEDTIDEVEQLHQKVEAAGMPADVRDKVENELQ
KLKMMSAISSEATVIRSYIEWMIQVPWHQRSKVKKDIVKAQQVLDTDHYGLDRVKERI
LEYLAVQARLNKVKGPILCLVGPPGVGKTSLGQSIANATGRKYVRMALGGVRDEAEIR
GHRKTYIGALPGKLIQKMAKVGVKNPLFLLDEIDKMASDMRGDPASALLEVLDPEQNT
TFNDHYLEVDYDLSDVMFVATSNSMNIPGPLLDRMEVIRLSGYTEDEKLNIAMRHLLA
KQIERNGLKKGELTVEESAILDIIRYYTREAGVRGLEREISKICRKAVKNLLVNPKLK
SITVNSDNLHDYLGVKRFEFGKADTQNRIGEVTGLAWTEVGGDLLTIETASVVGKGKL
SFTGSLGDVMKESIQAAMTVVRARADKLGINSEFHEKRDIHIHVPDGATPKDGPSAGI
AMCTALVSCLTGNPVRADVAMTGEISLRGKVLPIGGLKEKLLAAHRGGIKTVLIPKEN
VKDLEEIPENVKQNLAIHAVETIDEVLGLALENPPEGIEFVKVEAKPKAPRRKVTSKS
ERAVN"
misc_feature complement(<131717..131830)
/locus_tag="CGSHiEE_00680"
/note="Found in ATP-dependent protease La (LON); Region:
LON; smart00464"
/db_xref="CDD:197740"
misc_feature complement(129503..131827)
/locus_tag="CGSHiEE_00680"
/note="DNA-binding ATP-dependent protease La; Provisional;
Region: PRK10787"
/db_xref="CDD:182730"
misc_feature complement(130388..130861)
/locus_tag="CGSHiEE_00680"
/note="The AAA+ (ATPases Associated with a wide variety of
cellular Activities) superfamily represents an ancient
group of ATPases belonging to the ASCE (for additional
strand, catalytic E) division of the P-loop NTPase fold.
The ASCE division also includes ABC; Region: AAA; cd00009"
/db_xref="CDD:99707"
misc_feature complement(130763..130786)
/locus_tag="CGSHiEE_00680"
/note="Walker A motif; other site"
/db_xref="CDD:99707"
misc_feature complement(order(130433..130435,130583..130585,
130760..130783))
/locus_tag="CGSHiEE_00680"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:99707"
misc_feature complement(130580..130597)
/locus_tag="CGSHiEE_00680"
/note="Walker B motif; other site"
/db_xref="CDD:99707"
misc_feature complement(130400..130402)
/locus_tag="CGSHiEE_00680"
/note="arginine finger; other site"
/db_xref="CDD:99707"
misc_feature complement(129536..130147)
/locus_tag="CGSHiEE_00680"
/note="Lon protease (S16) C-terminal proteolytic domain;
Region: Lon_C; pfam05362"
/db_xref="CDD:191262"
gene 132125..132919
/locus_tag="CGSHiEE_00685"
/db_xref="GeneID:5225263"
CDS 132125..132919
/locus_tag="CGSHiEE_00685"
/note="COG2990 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290012.1"
/db_xref="GI:148825259"
/db_xref="GeneID:5225263"
/translation="MREKLRYYGYKWLYQKQCHQLVDFLNTETQWQSLFTQDYYRTNT
ILTTFCDKRFSASERLTAITENLRLAEEKMGRSLCQQLLDQQNIVLTQLTEDLRLSLS
INHIDPFEGYFSINIRNQNNERVYDASFTFLSPNKLLIASIQGPSSDNAQELVKQATK
ALHGMRPMFMLVNGFKMLAEKWQCELVGIPHKAQGKYRLSARSKILFNYDEFWQENQG
EYRHNYWQLPLHIERKQLEDIASKKRSMYRKRYEMLDQMALDIQQL"
misc_feature 132125..132913
/locus_tag="CGSHiEE_00685"
/note="Protein of unknown function (DUF535); Region:
DUF535; pfam04393"
/db_xref="CDD:146833"
gene complement(132969..133760)
/gene="mazG"
/locus_tag="CGSHiEE_00690"
/db_xref="GeneID:5225264"
CDS complement(132969..133760)
/gene="mazG"
/locus_tag="CGSHiEE_00690"
/EC_number="3.6.1.19"
/note="functions in degradation of stringent response
intracellular messenger ppGpp; in Escherichia coli this
gene is co-transcribed with the toxin/antitoxin genes
mazEF; activity of MazG is inhibited by MazEF in vitro;
ppGpp inhibits mazEF expression; MazG thus works in
limiting the toxic activity of the MazF toxin induced
during starvation; MazG also interacts with the GTPase
protein Era"
/codon_start=1
/transl_table=11
/product="nucleoside triphosphate pyrophosphohydrolase"
/protein_id="YP_001290013.1"
/db_xref="GI:148825260"
/db_xref="GeneID:5225264"
/translation="MRYSIQNFIQLIAQLRNPNGGCPWDLKQNYESMIPCLTEETYEV
IEAIEKKDIPNLREELGDLLLQVVFFSQLATEDKYFTFDDVLQDIAEKIVRRHPHVFG
DAKAGDETEALSRWNEMKAKEKQGKSEETSILDNVPRALPSLTRAAKLQKRCSKVGFD
WEEISPVFDKVREELEEVQAEINRTSIEQDKVEEEIGDLLFATVNLARHLKCDPEDAL
RKANLKFERRFRAVEQAVQQQGKQVNNVPLIELDLLWDEVKKQEN"
misc_feature complement(132972..133760)
/gene="mazG"
/locus_tag="CGSHiEE_00690"
/note="nucleoside triphosphate pyrophosphohydrolase;
Reviewed; Region: mazG; PRK09562"
/db_xref="CDD:181956"
misc_feature complement(133401..133745)
/gene="mazG"
/locus_tag="CGSHiEE_00690"
/note="Nucleoside Triphosphate Pyrophosphohydrolase (EC
3.6.1.8) N-terminal tandem-domain of MazG proteins from
Escherichia coli and bacterial homologs; Region:
NTP-PPase_MazG_Nterm; cd11528"
/db_xref="CDD:212135"
misc_feature complement(order(133482..133487,133491..133499,
133503..133517,133524..133526,133551..133553,
133560..133562,133566..133583,133590..133595,
133602..133604,133617..133619,133626..133628,
133635..133640,133647..133652,133659..133661,
133668..133673,133728..133730,133737..133742))
/gene="mazG"
/locus_tag="CGSHiEE_00690"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:212135"
misc_feature complement(order(133575..133577,133584..133586,
133632..133634,133641..133643))
/gene="mazG"
/locus_tag="CGSHiEE_00690"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:212135"
misc_feature complement(132984..133337)
/gene="mazG"
/locus_tag="CGSHiEE_00690"
/note="Nucleoside Triphosphate Pyrophosphohydrolase (EC
3.6.1.8) C-terminal tandem-domain of MazG proteins from
Escherichia coli and bacterial homologs'; Region:
NTP-PPase_MazG_Cterm; cd11529"
/db_xref="CDD:212136"
misc_feature complement(order(132996..132998,133008..133010,
133017..133019,133062..133064,133071..133076,
133083..133112,133116..133118,133125..133133,
133152..133154,133158..133163,133167..133175,
133179..133187,133224..133229,133245..133250,
133284..133292,133299..133301,133311..133313,
133320..133325,133329..133337))
/gene="mazG"
/locus_tag="CGSHiEE_00690"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:212136"
misc_feature complement(order(133167..133169,133176..133181,
133188..133190,133230..133232,133239..133241,
133251..133253,133278..133286))
/gene="mazG"
/locus_tag="CGSHiEE_00690"
/note="active site"
/db_xref="CDD:212136"
misc_feature complement(order(133167..133169,133176..133181,
133230..133232,133239..133244))
/gene="mazG"
/locus_tag="CGSHiEE_00690"
/note="putative chemical substrate binding site [chemical
binding]; other site"
/db_xref="CDD:212136"
misc_feature complement(order(133167..133169,133176..133178,
133230..133232,133239..133241))
/gene="mazG"
/locus_tag="CGSHiEE_00690"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:212136"
gene 133892..134431
/locus_tag="CGSHiEE_00695"
/db_xref="GeneID:5225265"
CDS 133892..134431
/locus_tag="CGSHiEE_00695"
/EC_number="2.4.2.9"
/note="regulates pyrimidine biosynthesis by binding to the
mRNA of the pyr genes, also has been shown to have uracil
phosphoribosyltransferase activity"
/codon_start=1
/transl_table=11
/product="bifunctional pyrimidine regulatory protein PyrR
uracil phosphoribosyltransferase"
/protein_id="YP_001290014.1"
/db_xref="GI:148825261"
/db_xref="GeneID:5225265"
/translation="MEKIIIDHDRFLRTISRISHEIIEKHQTLDDLVIVGIKRRGAEI
AELLQRRVEELSGINLPSMELDITFYRDDLTLVDQEDKMPVYSGSSQYLNIQDKTVIL
VDDVLFTGRTIRAAMDALTDFGRAAKIELVIFVDRGHRELPIRADYVGKNVPTSRDEL
VQVRTEKQDGCYEVAILGK"
misc_feature 133934..134341
/locus_tag="CGSHiEE_00695"
/note="Phosphoribosyl transferase (PRT)-type I domain;
Region: PRTases_typeI; cd06223"
/db_xref="CDD:206754"
misc_feature order(134003..134005,134009..134011,134201..134209,
134213..134227,134300..134302)
/locus_tag="CGSHiEE_00695"
/note="active site"
/db_xref="CDD:206754"
gene 134507..135442
/locus_tag="CGSHiEE_00700"
/db_xref="GeneID:5225266"
CDS 134507..135442
/locus_tag="CGSHiEE_00700"
/note="COG0760 Parvulin-like peptidyl-prolyl isomerase"
/codon_start=1
/transl_table=11
/product="stationary-phase survival protein SurA"
/protein_id="YP_001290015.1"
/db_xref="GI:148825262"
/db_xref="GeneID:5225266"
/translation="MKKFILKSFLLATLGCVAFTSMAQAEERVVATVDGIPVLESQVR
ANMGKKGDRQSAIDKIIDDILVQKAVQESGVKIDPREIDHIVEDTAARNGLTYGQFLD
ALDYQGISLNAFRQQIANQMVMGAVRNKAIQESIDVTREEVVALGQKMLEEAKEKGTA
QKVMGKEYEVRHILLKLNPLLNDAQAKKQLAKIRSDIIAGKTTFADAALKYSKDYLSG
ANGGSLGYAFPETYAPQFAQTVVKSKQGVISAPFKTEFGWHILEVTGVRDGDLTAEAY
TQKAYERLVNTQLQDATNDWVKALRKRANIQYFNK"
misc_feature 134531..135439
/locus_tag="CGSHiEE_00700"
/note="Parvulin-like peptidyl-prolyl isomerase
[Posttranslational modification, protein turnover,
chaperones]; Region: SurA; COG0760"
/db_xref="CDD:31103"
misc_feature 134588..134890
/locus_tag="CGSHiEE_00700"
/note="SurA N-terminal domain; Region: SurA_N_3; cl07813"
/db_xref="CDD:208773"
misc_feature 135020..135301
/locus_tag="CGSHiEE_00700"
/note="PPIC-type PPIASE domain; Region: Rotamase;
pfam00639"
/db_xref="CDD:201365"
gene 135512..136555
/locus_tag="CGSHiEE_00705"
/db_xref="GeneID:5225267"
CDS 135512..136555
/locus_tag="CGSHiEE_00705"
/EC_number="2.4.2.9"
/note="COG1559 Predicted periplasmic solute-binding
protein"
/codon_start=1
/transl_table=11
/product="pyrimidine regulatory protein PyrR"
/protein_id="YP_001290016.1"
/db_xref="GI:148825263"
/db_xref="GeneID:5225267"
/translation="MKKFLIAILLLILILAGAASFAYYKMTEFVKTPVNVQADQLLTI
ERGTTGSKLATLFEQEKLIADGKLLPYLLKLKPELNKIKAGTYSLENVKTVQDLLDLL
NSGKEVQFNVKWIEGKTFKDWRKDLENAPHLVQTLKDKSNEDIFTLLDLPDVGQNLEL
KNVEGWLYPDTYNYTPKSTDLELLKRSAERMKKALNKAWNERDEDLPLANPYEMLILA
SIVEKETGIANERAKVASVFINRLKAKMKLQTDPTVIYGMGENYNGNIRKKDLETKTP
YNTYVIDGLPPTPIAMPSESSLQAVAKPEKTDFYYFVADGSGGHKFTRNLNEHNKAVQ
EYLRWYRSQKNAK"
misc_feature 135635..136519
/locus_tag="CGSHiEE_00705"
/note="YceG-like family; Region: YceG; pfam02618"
/db_xref="CDD:202312"
misc_feature 135755..136510
/locus_tag="CGSHiEE_00705"
/note="proteins similar to Escherichia coli yceG; Region:
yceG_like; cd08010"
/db_xref="CDD:153433"
misc_feature order(135755..135757,135761..135778,135803..135805,
135815..135817,135836..135841,135848..135850,
136256..136258,136262..136264,136313..136315,
136322..136324,136463..136468,136487..136489,
136496..136501,136508..136510)
/locus_tag="CGSHiEE_00705"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:153433"
gene 136572..137204
/gene="tmk"
/locus_tag="CGSHiEE_00710"
/db_xref="GeneID:5225277"
CDS 136572..137204
/gene="tmk"
/locus_tag="CGSHiEE_00710"
/EC_number="2.7.4.9"
/note="catalyzes the reversible phosphoryl transfer from
adenosine triphosphate (ATP) to thymidine monophosphate
(dTMP) to form thymidine diphosphate (dTDP)"
/codon_start=1
/transl_table=11
/product="thymidylate kinase"
/protein_id="YP_001290017.1"
/db_xref="GI:148825264"
/db_xref="GeneID:5225277"
/translation="MKGKFIVIEGLEGAGKSSAHQSVVRVLHELAIQDVVFTREPGGT
PLAEKLRHLIKHETEEPVTHKAELLMLYAARIQLVDNVIKPALMQGKWVVGDRHDMSS
QAYQGGGRQLDPHFMLTLKETVLGDFEPDLTIYLDIDPIVGLARARGRGELDRIEQMD
LDFFHRTRARYLELVKDNPKAVMINAEQSIELVQADIERAVKNWWKSNEK"
misc_feature 136572..137189
/gene="tmk"
/locus_tag="CGSHiEE_00710"
/note="thymidylate kinase; Validated; Region: tmk;
PRK00698"
/db_xref="CDD:179089"
misc_feature 136581..137177
/gene="tmk"
/locus_tag="CGSHiEE_00710"
/note="Thymidine monophosphate kinase (TMPK), also known
as thymidylate kinase, catalyzes the phosphorylation of
thymidine monophosphate (TMP) to thymidine diphosphate
(TDP) utilizing ATP as its preferred phophoryl donor. TMPK
represents the rate-limiting step...; Region: TMPK;
cd01672"
/db_xref="CDD:30190"
misc_feature order(136620..136622,136782..136784,136794..136796,
136857..136862,136884..136886,137019..137021)
/gene="tmk"
/locus_tag="CGSHiEE_00710"
/note="TMP-binding site; other site"
/db_xref="CDD:30190"
misc_feature order(136623..136625,137007..137009,137127..137129)
/gene="tmk"
/locus_tag="CGSHiEE_00710"
/note="ATP-binding site [chemical binding]; other site"
/db_xref="CDD:30190"
gene 137201..138184
/locus_tag="CGSHiEE_00715"
/db_xref="GeneID:5225278"
CDS 137201..138184
/locus_tag="CGSHiEE_00715"
/EC_number="2.7.7.7"
/note="catalyzes the DNA-template-directed extension of
the 3'-end of a DNA strand; the delta' subunit seems to
interact with the gamma subunit to transfer the beta
subunit on the DNA"
/codon_start=1
/transl_table=11
/product="DNA polymerase III subunit delta'"
/protein_id="YP_001290018.1"
/db_xref="GI:148825265"
/db_xref="GeneID:5225278"
/translation="MTALYPWLTPIYHQIAQTFDEGLGHHAVLIKADSGLGVESLFNA
LAQKIMCVAQGDKPCGQCHSCHLMQAHSHPDYHELSPIDGKDIGVDQVRDINEIVAQH
AQQNGNKVVYVQGVERLTEAAANALLKTLEEPRPNTYFLLQADSSASLLATIYSRCQV
WNLSVPNEQTAVDWLKSKSAVENQEILTALAMNLGRPLLALETLQEGFIEQRKNFLRQ
FWVFYRRRSPLELLPLFDKERYVQQVDWILAFLSDCLKHKLEIDSHRQVADLGRGIEQ
FSNEQTALGLLQAIKIMQQVRSDLLTINGVNVELMLLDGLMRLVTEVFETQ"
misc_feature 137204..138175
/locus_tag="CGSHiEE_00715"
/note="DNA polymerase III subunit delta'; Validated;
Region: PRK06871"
/db_xref="CDD:180738"
misc_feature <137561..>137719
/locus_tag="CGSHiEE_00715"
/note="P-loop containing Nucleoside Triphosphate
Hydrolases; Region: P-loop_NTPase; cl09099"
/db_xref="CDD:213113"
misc_feature 137813..138169
/locus_tag="CGSHiEE_00715"
/note="DNA polymerase III, delta subunit, C terminal;
Region: DNApol3-delta_C; pfam09115"
/db_xref="CDD:192213"
gene 138238..139020
/locus_tag="CGSHiEE_00720"
/db_xref="GeneID:5225279"
CDS 138238..139020
/locus_tag="CGSHiEE_00720"
/codon_start=1
/transl_table=11
/product="putative deoxyribonuclease"
/protein_id="YP_001290019.1"
/db_xref="GI:148825266"
/db_xref="GeneID:5225279"
/translation="MFIVDSHCHLDALDYENLHKNIADVVEKARARDVKHLLAIGVTL
SRFEQAYDSLREFNNVSLACGVHPLDFEEESYDAERLLRLAQDPKVIAIGEIGLDYYY
SADNKAAQQVVFGSQIDIANQLDKPVIIHTRSAGDDTIAMLREQHAEKCGGVIHCFTE
TMEFAKKALDLGFYISCSGIVTFKNAEAIREVIRYVPMERLLVETDSPYLAPVPYRGK
ENQPAYTREVCEYVATLKGVSAEAFAQITTQNFERLFKIRVE"
misc_feature 138244..139005
/locus_tag="CGSHiEE_00720"
/note="TatD like proteins; E.coli TatD is a cytoplasmic
protein, shown to have magnesium dependent DNase activity;
Region: TatD_DNAse; cd01310"
/db_xref="CDD:30053"
misc_feature order(138256..138258,138262..138264,138628..138630,
138703..138705,138853..138855)
/locus_tag="CGSHiEE_00720"
/note="active site"
/db_xref="CDD:30053"
gene 139103..139570
/locus_tag="CGSHiEE_00725"
/db_xref="GeneID:5225280"
CDS 139103..139570
/locus_tag="CGSHiEE_00725"
/note="COG0084 Mg-dependent DNase"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290020.1"
/db_xref="GI:148825267"
/db_xref="GeneID:5225280"
/translation="MFSVVNYVFPHYDVTRVTGVEVKRVDKDGPITKSNPADGPTRDV
YYINTQNDDGKIMVYRNEDTRWGFPFYFKFGSANLQAEAQALGNDNKLVQIKYYGWRI
TIVDEYRNATSIKEITADDTPSNPIVSWILYVFLLAILFLSIQFIRGWFDSDK"
misc_feature 139103..139555
/locus_tag="CGSHiEE_00725"
/note="Protein of unknown function (DUF1523); Region:
DUF1523; pfam07509"
/db_xref="CDD:116129"
gene 139627..140919
/locus_tag="CGSHiEE_00730"
/db_xref="GeneID:5225281"
CDS 139627..140919
/locus_tag="CGSHiEE_00730"
/note="COG1253 Hemolysins and related proteins containing
CBS domains"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290021.1"
/db_xref="GI:148825268"
/db_xref="GeneID:5225281"
/translation="MELFHTILAIVALILSSAVVSSAEISLASSRKLKLQSLANEGDV
RALQVLKLQEHPGRFITVVQILLNMVAILGGGIGESALSPYIADILNRSFEGNWIEPT
ASTIAFILVTCLFILFADLIPKRIAITYPEMVALRVVGIMNFSMYVFKPLVWFFDTLA
NAFFRLFRISTVREDGMTSEDIFAVVEAGAEAGVLKTQEHYLIENIFDMQARTVTSTM
TTRENIVYLDRTFSRQEVMDTLSRNSHSKIVICDNGLDKILGYIESHTLLTMYLQNEN
VVLTDPKLLRKALFVPDTLSLYEVLELFKSTGEDFAIIVNEYALVVGIVTLNDVMSIV
MGELVSNEEEYIVSRDENSWLIDGATPLEEVTRVLDIAYFPDEENYETISGFMMYMLR
KIPKKTDSVVYGKYKFEVIDTENFKIDQILVSLVKEQE"
misc_feature 139717..140916
/locus_tag="CGSHiEE_00730"
/note="Hemolysins and related proteins containing CBS
domains [General function prediction only]; Region: TlyC;
COG1253"
/db_xref="CDD:31445"
misc_feature 139717..140172
/locus_tag="CGSHiEE_00730"
/note="Domain of unknown function DUF21; Region: DUF21;
pfam01595"
/db_xref="CDD:201879"
misc_feature 140290..140619
/locus_tag="CGSHiEE_00730"
/note="This cd contains two tandem repeats of the
cystathionine beta-synthase (CBS pair) domains associated
with the CorC_HlyC domain. CorC_HlyC is a transporter
associated domain. This small domain is found in Na+/H+
antiporters, in proteins involved in...; Region:
CBS_pair_CorC_HlyC_assoc; cd04590"
/db_xref="CDD:73090"
misc_feature 140665..140904
/locus_tag="CGSHiEE_00730"
/note="Transporter associated domain; Region: CorC_HlyC;
smart01091"
/db_xref="CDD:198159"
gene 140991..141182
/locus_tag="CGSHiEE_00735"
/db_xref="GeneID:5225331"
CDS 140991..141182
/locus_tag="CGSHiEE_00735"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290022.1"
/db_xref="GI:148825269"
/db_xref="GeneID:5225331"
/translation="MELRQQIPTGCIKQFGQFGVPYVVGEVAEFLPDGDVLVNITLLQ
SGEKDIYRLSHLLEDPEAE"
gene 141191..141328
/locus_tag="CGSHiEE_00740"
/db_xref="GeneID:5225332"
CDS 141191..141328
/locus_tag="CGSHiEE_00740"
/codon_start=1
/transl_table=11
/product="virulence-associated protein D"
/protein_id="YP_001290023.1"
/db_xref="GI:148825270"
/db_xref="GeneID:5225332"
/translation="MYAIAFDLVVKDTQDYHPKGVQEAYTDIRAFRIEQWSDFTDFIR
N"
misc_feature 141191..>141283
/locus_tag="CGSHiEE_00740"
/note="CRISPR/Cas system-associated protein Cas2; Region:
Cas2_I_II_III; cl11442"
/db_xref="CDD:209324"
gene 141509..141952
/locus_tag="CGSHiEE_00745"
/db_xref="GeneID:5225333"
CDS 141509..141952
/locus_tag="CGSHiEE_00745"
/note="COG1191 DNA-directed RNA polymerase specialized
sigma subunit"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290024.1"
/db_xref="GI:148825271"
/db_xref="GeneID:5225333"
/translation="MGNDKKVIDLDKDKIDQKSYAAAYEATVATYKGRVNENFFVDNF
ASGANDWYLGRILVPVKQIQDKLYTGGHDSDVYAYYSGVLHAEALQANLKRLSANCWE
KVDSQSMAQGIYDAMRDLQKGEARGENDEYIVQGSEALLKACTSK"
gene 142024..143523
/locus_tag="CGSHiEE_00750"
/db_xref="GeneID:5225334"
CDS 142024..143523
/locus_tag="CGSHiEE_00750"
/note="phosphoenolpyruvate (PEP)-dependent, sugar
transporting phosphotransferase system; catalyzes the
phosphorylation of incoming sugar substrates concomitant
with their translocation across the cell membrane; IIA is
phosphorylated by phospho-HP which then transfers the
phosphoryl group to the IIB componentr"
/codon_start=1
/transl_table=11
/product="bifunctional PTS system fructose-specific
transporter subunit IIA/HPr protein"
/protein_id="YP_001290025.1"
/db_xref="GI:148825272"
/db_xref="GeneID:5225334"
/translation="MLELSESNIHLNANAIDKQQAIEMAASALVQADNVENGYLQGML
ARELQTSTFLGNGIAIPHGTLDTRLMVKKTGVQVFQFPQGIEWGEGNIAYVVIGIAAR
SDEHLSLLRQLTHVLSDEDTAAKLAKITDVAEFCAILMGETIEPFEIPAANISLDVNT
QSLLTLVAINAGQLQVQSAVENRFISEVINNAALPLGKGLWVTDSVVGNVKNALAFSR
AKTIFSHNGKAVKGVITVSAVGDQINPTLARLLDDDVQTTLLNGNSTEILTALLGSSS
DVETQSVEGAVVGTFTIRNEHGLHARPSANLVNEVKKFTSKITMQNLTRESEVVSAKS
LMKIVALGVTQGHRLRFVAEGEDAKQAIESLGKAIANGLGENVSAVPPSEPDTIEIMG
DQIHTSAVTEDDNLPANAIEAVFVIKNEQGLHARPSAILVNEVKKYNASVAVQNLDRN
SQLVSAKSLMKIVALGVVKGTRLRFVATGDEAQQAIDGICAVIESGLGE"
misc_feature 142024..143520
/locus_tag="CGSHiEE_00750"
/note="bifunctional PTS system fructose-specific
transporter subunit IIA/HPr protein; Provisional; Region:
PRK13779"
/db_xref="CDD:172317"
misc_feature 142033..142440
/locus_tag="CGSHiEE_00750"
/note="PTS_IIA, PTS system, fructose/mannitol specific IIA
subunit. The bacterial phosphoenolpyruvate: sugar
phosphotransferase system (PTS) is a multi-protein system
involved in the regulation of a variety of metabolic and
transcriptional processes. This...; Region: PTS_IIA_fru;
cd00211"
/db_xref="CDD:29266"
misc_feature order(142159..142161,142207..142209)
/locus_tag="CGSHiEE_00750"
/note="active site"
/db_xref="CDD:29266"
misc_feature 142207..142209
/locus_tag="CGSHiEE_00750"
/note="phosphorylation site [posttranslational
modification]"
/db_xref="CDD:29266"
misc_feature 142891..143130
/locus_tag="CGSHiEE_00750"
/note="Histidine-containing phosphocarrier protein
(HPr)-like proteins. HPr is a central component of the
bacterial phosphoenolpyruvate sugar phosphotransferase
system (PTS). The PTS catalyses the phosphorylation of
sugar substrates during their translocation...; Region:
PTS-HPr_like; cd00367"
/db_xref="CDD:29444"
misc_feature 142891..142902
/locus_tag="CGSHiEE_00750"
/note="dimerization domain swap beta strand [polypeptide
binding]; other site"
/db_xref="CDD:29444"
misc_feature order(142918..142920,142924..142929,142933..142938,
142948..142950,142957..142959,143020..143031,
143038..143043)
/locus_tag="CGSHiEE_00750"
/note="regulatory protein interface [polypeptide binding];
other site"
/db_xref="CDD:29444"
misc_feature 142921..142923
/locus_tag="CGSHiEE_00750"
/note="active site"
/db_xref="CDD:29444"
misc_feature 143023..143025
/locus_tag="CGSHiEE_00750"
/note="regulatory phosphorylation site [posttranslational
modification]; other site"
/db_xref="CDD:29444"
misc_feature 143266..143502
/locus_tag="CGSHiEE_00750"
/note="Histidine-containing phosphocarrier protein
(HPr)-like proteins. HPr is a central component of the
bacterial phosphoenolpyruvate sugar phosphotransferase
system (PTS). The PTS catalyses the phosphorylation of
sugar substrates during their translocation...; Region:
PTS-HPr_like; cd00367"
/db_xref="CDD:29444"
misc_feature 143266..143274
/locus_tag="CGSHiEE_00750"
/note="dimerization domain swap beta strand [polypeptide
binding]; other site"
/db_xref="CDD:29444"
misc_feature order(143290..143292,143296..143301,143305..143310,
143320..143322,143329..143331,143392..143403,
143410..143415)
/locus_tag="CGSHiEE_00750"
/note="regulatory protein interface [polypeptide binding];
other site"
/db_xref="CDD:29444"
misc_feature 143293..143295
/locus_tag="CGSHiEE_00750"
/note="active site"
/db_xref="CDD:29444"
misc_feature 143395..143397
/locus_tag="CGSHiEE_00750"
/note="regulatory phosphorylation site [posttranslational
modification]; other site"
/db_xref="CDD:29444"
gene 143525..144466
/gene="fruK"
/locus_tag="CGSHiEE_00755"
/db_xref="GeneID:5225335"
CDS 143525..144466
/gene="fruK"
/locus_tag="CGSHiEE_00755"
/EC_number="2.7.1.56"
/note="converts fructose-1-phosphate and ATP to
fructose-1,6-bisphosphate and ADP; highly specific for
fructose-1-phopshate; similar to PfkB; forms homodimers"
/codon_start=1
/transl_table=11
/product="1-phosphofructokinase"
/protein_id="YP_001290026.1"
/db_xref="GI:148825273"
/db_xref="GeneID:5225335"
/translation="MASVVTITLNAAYDLVGRLNRIQLGEVNTVETLGLFPAGKGINV
AKVLKDLGVDVAVGGFLGEDNSADFEQMFNQHGLEDKFHRVDGKTRINVKITETEADV
TDLNFLGYQISPQVWQQFVTDSLAYCLNYDIVAVCGSLPRGVSPELFADWLNQLHKAG
VKVVLDSSNAALAAGLKAKPWLVKPNHRELEALVGHSLNSLEEIIAAAQQLKAEDIEN
VIISMGEKGSLWINNEGSLKAEPPKCENVVSTVGAGDSMVAGLIYGFEKGLSKAETLA
FATAVSAFAVSQSNVGVSDLSLLDPILEKVQITMIEG"
misc_feature 143534..144460
/gene="fruK"
/locus_tag="CGSHiEE_00755"
/note="Fructose-1-phosphate kinase and related
fructose-6-phosphate kinase (PfkB) [Carbohydrate transport
and metabolism]; Region: FruK; COG1105"
/db_xref="CDD:31302"
misc_feature 143534..144343
/gene="fruK"
/locus_tag="CGSHiEE_00755"
/note="1-phosphofructokinase (FruK), minor
6-phosphofructokinase (pfkB) and related sugar kinases.
FruK plays an important role in the predominant pathway
for fructose utilisation.This group also contains
tagatose-6-phophate kinase, an enzyme of the tagatose...;
Region: FruK_PfkB_like; cd01164"
/db_xref="CDD:29349"
misc_feature order(143657..143659,143669..143671,143687..143689,
143693..143695,143933..143935)
/gene="fruK"
/locus_tag="CGSHiEE_00755"
/note="putative substrate binding site [chemical binding];
other site"
/db_xref="CDD:29349"
misc_feature order(144020..144022,144074..144076,144080..144082,
144188..144190,144206..144208,144281..144283,
144287..144289)
/gene="fruK"
/locus_tag="CGSHiEE_00755"
/note="putative ATP binding site [chemical binding]; other
site"
/db_xref="CDD:29349"
gene 144468..146138
/gene="fruK"
/locus_tag="CGSHiEE_00760"
/db_xref="GeneID:5225336"
CDS 144468..146138
/gene="fruK"
/locus_tag="CGSHiEE_00760"
/EC_number="2.7.1.56"
/note="COG3925 N-terminal domain of the phosphotransferase
system fructose-specific component IIB"
/codon_start=1
/transl_table=11
/product="1-phosphofructokinase"
/protein_id="YP_001290027.1"
/db_xref="GI:148825274"
/db_xref="GeneID:5225336"
/translation="MKLFLTQSANVGNAKAYLLHEVFRAAAQKANVSIVETAAEADLV
LVFGSVLPNNPDLVGKKVFIIGEAIAMISPEVTLANALANGADYVAPKSAVSFTGVSG
VKNIVAVTACPTGVAHTFMSAEAIEAYAKKQGWNVKVETRGQVGTGNEITAEEVAAAD
LVFIAADIDVPLDKFKGKPMYRTSTGLALKKTEQEFDKAFKEAKVFDGGNNAGVKEES
REKKGVYKHLMTGVSHMLPLVVAGGLLIAISFMFSFNVIENTGVFQDLPNMLMNIGSG
VAFKLMIAVFAGYVAFSIADRPGLAVGLIAGMLASEAGAGILGGIIAGFLAGYVVKGL
NVIIRLPASLTSLKPILILPLLGSMIVGLTMIYLINPPVAEIMKELSNWLTSMGEVNA
IVLGAIIGAMMCIDMGGPVNKAAYTFSVGLIASQVYTPMAAAMAAGMVPPIGMAVATW
IARNKFTVSQRDAGKASFVLGLCFISEGALPFVAADPIRVIISSVIGGAVAGAISMGL
NITLQAPHGGLFVIPFVSEPLKYLGAIAIGALSTGVVYAIIKSKNNAE"
misc_feature 144468..146135
/gene="fruK"
/locus_tag="CGSHiEE_00760"
/note="PTS system fructose-specific transporter subunits
IIBC; Provisional; Region: PRK10712"
/db_xref="CDD:182667"
misc_feature 144468..144776
/gene="fruK"
/locus_tag="CGSHiEE_00760"
/note="N-terminal domain of the phosphotransferase system
fructose-specific component IIB [Carbohydrate transport
and metabolism]; Region: COG3925"
/db_xref="CDD:33710"
misc_feature 144783..145070
/gene="fruK"
/locus_tag="CGSHiEE_00760"
/note="PTS_IIB_fructose: subunit IIB of enzyme II (EII) of
the fructose-specific phosphoenolpyruvate:carbohydrate
phosphotransferase system (PTS). In this system, EII (also
referred to as FruAB) is a fructose-specific permease made
up of two proteins (FruA and...; Region: PTS_IIB_fructose;
cd05569"
/db_xref="CDD:99911"
misc_feature order(144801..144812,144816..144824)
/gene="fruK"
/locus_tag="CGSHiEE_00760"
/note="P-loop; other site"
/db_xref="CDD:99911"
misc_feature order(144801..144803,144807..144812,144819..144824)
/gene="fruK"
/locus_tag="CGSHiEE_00760"
/note="active site"
/db_xref="CDD:99911"
misc_feature 144801..144803
/gene="fruK"
/locus_tag="CGSHiEE_00760"
/note="phosphorylation site [posttranslational
modification]"
/db_xref="CDD:99911"
misc_feature 145095..146117
/gene="fruK"
/locus_tag="CGSHiEE_00760"
/note="PTS system, fructose subfamily, IIC component;
Region: PTS_IIC_fructo; TIGR01427"
/db_xref="CDD:162354"
gene complement(146573..146658)
/locus_tag="CGSHiEE_t09342"
/db_xref="GeneID:5542112"
tRNA complement(146573..146658)
/locus_tag="CGSHiEE_t09342"
/product="tRNA-Leu"
/db_xref="GeneID:5542112"
gene complement(146684..147022)
/gene="secG"
/locus_tag="CGSHiEE_00765"
/db_xref="GeneID:5225663"
CDS complement(146684..147022)
/gene="secG"
/locus_tag="CGSHiEE_00765"
/note="COG1314 Preprotein translocase subunit SecG"
/codon_start=1
/transl_table=11
/product="preprotein translocase subunit SecG"
/protein_id="YP_001290028.1"
/db_xref="GI:148825275"
/db_xref="GeneID:5225663"
/translation="MYQVLLFIYVVVAIALIGFILVQQGKGANAGASFGGGASGTMFG
SAGAGNFLTRTSAILATAFFVIALVLGNMNSHKGNVQKGAFDDLSQAAEQVQQQAAPA
KENQNSDIPQ"
misc_feature complement(146795..147022)
/gene="secG"
/locus_tag="CGSHiEE_00765"
/note="preprotein translocase subunit SecG; Reviewed;
Region: secG; PRK06870"
/db_xref="CDD:180737"
gene complement(147130..149085)
/locus_tag="CGSHiEE_00770"
/db_xref="GeneID:5225664"
CDS complement(147130..149085)
/locus_tag="CGSHiEE_00770"
/note="decatenates replicating daughter chromosomes"
/codon_start=1
/transl_table=11
/product="DNA topoisomerase III"
/protein_id="YP_001290029.1"
/db_xref="GI:148825276"
/db_xref="GeneID:5225664"
/translation="MRLFIAEKPSLARAIADVLPKPHQRGDGFIKCGDNDVVTWCVGH
LLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLLPRKEVKKQLSVVEKLIHQADTLVNAG
DPDREGQLLVDEVFSYANLAAEKRDKILRCLISDLNPSAVEKAVKKLQPNRNFIPLAT
SALARARADWLYGINMTRAYTIRGRQTGYDGVLSVGRVQTPVLGLIVRRDLEIEHFQP
KDFFEVQAWINPDNKEEKTQEKSTALFSALWQPSKACEDYQDDDGRVLSKGLAENVVK
RITNQPAEVTEYKDVREKETPPLPYSLSALQIDAAKRFGMSAQAVLDTCQRLYETHRL
ITYPRSDCRYLPEEHFAERHNVLNAISTHCEVYQRLPNVISTEQRNRCWNNKKVEAHH
AIIPTAKNRPVNLTQEERNIYSLIARQYLMQFCPDAEYRKSKITLNIAGGAFIAQARN
LQTAGWKELLGKEDDTENQEPLLPIVKKGQILHCERGEVISKKTQPPKPFTDATLLSA
MTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLTKKGRNIHSTETGRIL
IQALPDIATQPDMTAHWESQLTDISQKQATYQQFMHNLNQMLPDLVRFVDLNALRQLS
QIKMIKSNKTKPKSAVKKSSKSNGETD"
misc_feature complement(147250..149085)
/locus_tag="CGSHiEE_00770"
/note="DNA topoisomerase III, bacteria and conjugative
plasmid; Region: topB; TIGR01056"
/db_xref="CDD:162178"
misc_feature complement(148639..149085)
/locus_tag="CGSHiEE_00770"
/note="TOPRIM_TopoIA_TopoIII: The topoisomerase-primase
(TORPIM) domain found in members of the type IA family of
DNA topoisomerases (Topo IA) similar to topoisomerase III.
Type IA DNA topoisomerases remove (relax) negative
supercoils in the DNA by: cleaving...; Region:
TOPRIM_TopoIA_TopoIII; cd03362"
/db_xref="CDD:173782"
misc_feature complement(order(148765..148767,148771..148773,
148777..148779,149053..149055,149062..149067))
/locus_tag="CGSHiEE_00770"
/note="active site"
/db_xref="CDD:173782"
misc_feature complement(order(148735..148740,148744..148749,
148768..148770,148774..148776,149044..149046))
/locus_tag="CGSHiEE_00770"
/note="putative interdomain interaction site [polypeptide
binding]; other site"
/db_xref="CDD:173782"
misc_feature complement(order(148771..148773,148777..148779))
/locus_tag="CGSHiEE_00770"
/note="putative metal-binding site [ion binding]; other
site"
/db_xref="CDD:173782"
misc_feature complement(148768..148770)
/locus_tag="CGSHiEE_00770"
/note="putative nucleotide binding site [chemical
binding]; other site"
/db_xref="CDD:173782"
misc_feature complement(147250..148620)
/locus_tag="CGSHiEE_00770"
/note="DNA Topoisomerase, subtype IA; DNA-binding,
ATP-binding and catalytic domain of bacterial DNA
topoisomerases I and III, and eukaryotic DNA topoisomerase
III and eubacterial and archael reverse gyrases.
Topoisomerases clevage single or double stranded DNA...;
Region: TOP1Ac; cd00186"
/db_xref="CDD:73184"
misc_feature complement(order(148447..148509,148537..148620))
/locus_tag="CGSHiEE_00770"
/note="domain I; other site"
/db_xref="CDD:73184"
misc_feature complement(order(147445..147450,147460..147462,
147466..147471,147478..147483,148069..148071,
148096..148098,148108..148110,148555..148557,
148567..148569,148579..148581,148588..148593))
/locus_tag="CGSHiEE_00770"
/note="DNA binding groove [nucleotide binding]"
/db_xref="CDD:73184"
misc_feature complement(order(147373..147375,148462..148464,
148474..148476))
/locus_tag="CGSHiEE_00770"
/note="phosphate binding site [ion binding]; other site"
/db_xref="CDD:73184"
misc_feature complement(order(147601..147633,147706..147762,
147766..147810,148198..148251,148405..148419))
/locus_tag="CGSHiEE_00770"
/note="domain II; other site"
/db_xref="CDD:73184"
misc_feature complement(order(147811..147873,147892..147918,
148003..148086,148090..148173,148177..148197))
/locus_tag="CGSHiEE_00770"
/note="domain III; other site"
/db_xref="CDD:73184"
misc_feature complement(order(147415..147417,147481..147483,
147487..147489,147832..147834,147844..147846,
147853..147855,147913..147915,148144..148152,
148162..148164))
/locus_tag="CGSHiEE_00770"
/note="nucleotide binding site [chemical binding]; other
site"
/db_xref="CDD:73184"
misc_feature complement(order(147913..147915,148069..148071,
148075..148077))
/locus_tag="CGSHiEE_00770"
/note="catalytic site [active]"
/db_xref="CDD:73184"
misc_feature complement(order(147250..147363,147373..147417,
147427..147507,147559..147600))
/locus_tag="CGSHiEE_00770"
/note="domain IV; other site"
/db_xref="CDD:73184"
gene complement(149101..149703)
/gene="recR"
/locus_tag="CGSHiEE_00775"
/db_xref="GeneID:5225665"
CDS complement(149101..149703)
/gene="recR"
/locus_tag="CGSHiEE_00775"
/note="involved in a recombinational process of DNA
repair, independent of the recBC complex"
/codon_start=1
/transl_table=11
/product="recombination protein RecR"
/protein_id="YP_001290030.1"
/db_xref="GI:148825277"
/db_xref="GeneID:5225665"
/translation="MQSSPLLEHLIENLRCLPGVGPKSAQRMAYHLLQRNRSGGMNLA
RALTEAMSKIGHCSQCRDFTEEDTCNICNNPRRQNSGLLCVVEMPADIQAIEQTGQFS
GRYFVLMGHLSPLDGIGPREIGLDLLQKRLVEESFHEVILATNPTVEGDATANYIAEM
CRQHNIKVSRIAHGIPVGGELETVDGTTLTHSFLGRRQID"
misc_feature complement(149107..149700)
/gene="recR"
/locus_tag="CGSHiEE_00775"
/note="recombination protein RecR; Reviewed; Region: recR;
PRK00076"
/db_xref="CDD:178844"
misc_feature complement(149473..149592)
/gene="recR"
/locus_tag="CGSHiEE_00775"
/note="RecR protein; Region: RecR; pfam02132"
/db_xref="CDD:202123"
misc_feature complement(149128..149463)
/gene="recR"
/locus_tag="CGSHiEE_00775"
/note="TOPRIM_recR: topoisomerase-primase (TOPRIM)
nucleotidyl transferase/hydrolase domain of the type found
in Escherichia coli RecR. RecR participates in the RecFOR
pathway of homologous recombinational repair in
prokaryotes. This pathway provides a...; Region:
TOPRIM_recR; cd01025"
/db_xref="CDD:173775"
misc_feature complement(order(149257..149259,149263..149265,
149269..149271,149431..149433,149440..149445))
/gene="recR"
/locus_tag="CGSHiEE_00775"
/note="putative active site [active]"
/db_xref="CDD:173775"
misc_feature complement(order(149269..149271,149443..149445))
/gene="recR"
/locus_tag="CGSHiEE_00775"
/note="putative metal-binding site [ion binding]; other
site"
/db_xref="CDD:173775"
misc_feature complement(order(149128..149136,149140..149142,
149146..149148,149161..149163,149167..149202,
149230..149232,149266..149268,149275..149277,
149281..149283,149287..149289,149410..149415,
149419..149427))
/gene="recR"
/locus_tag="CGSHiEE_00775"
/note="tetramer interface [polypeptide binding]; other
site"
/db_xref="CDD:173775"
gene complement(149761..150090)
/locus_tag="CGSHiEE_00780"
/db_xref="GeneID:5225666"
CDS complement(149761..150090)
/locus_tag="CGSHiEE_00780"
/note="COG0718 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290031.1"
/db_xref="GI:148825278"
/db_xref="GeneID:5225666"
/translation="MFGKGGLGGLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKI
AINGAHNCRRIDIDPSLMEDDKEMLEDLIAAAFNDAVRRAEELQKEKMASVTAGMPLP
PGMKFPF"
misc_feature complement(149776..>150000)
/locus_tag="CGSHiEE_00780"
/note="hypothetical protein; Validated; Region: PRK00153"
/db_xref="CDD:178904"
gene complement(150243..151088)
/locus_tag="CGSHiEE_00785"
/db_xref="GeneID:5225667"
CDS complement(150243..151088)
/locus_tag="CGSHiEE_00785"
/note="COG2961 Protein involved in catabolism of external
DNA"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290032.1"
/db_xref="GI:148825279"
/db_xref="GeneID:5225667"
/translation="MLSYRHSFHAGNHADVLKHIVLMLILENLKLKEKGFFYLDTHSG
VGRYRLSSNESEKTGEYKEGIGRLWDQTYLPEDVARYVKMIKKLNYGGKELRYYAGSP
LIAAELLRPQDRALLTELHPSDYPILRNNFNDDKNVSVKCDNGFQQVKATLPPKERRG
LVLIDPPYELKEDYDLVVKAIEEGYKRFATGTYAIWYPVVLRQQTKRIFKGLEATGIR
KILKIELAVRPDSDQRGMTASGMVVINPPWTLETQMKEILPYLTKTLVPEGTGSWTVE
WITPE"
misc_feature complement(150246..151085)
/locus_tag="CGSHiEE_00785"
/note="Protein involved in catabolism of external DNA
[General function prediction only]; Region: ComJ; COG2961"
/db_xref="CDD:32781"
misc_feature complement(<150543..>150818)
/locus_tag="CGSHiEE_00785"
/note="S-adenosylmethionine-dependent methyltransferases
(SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
that use S-adenosyl-L-methionine (SAM or AdoMet) as a
substrate for methyltransfer, creating the product
S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
cl16911"
/db_xref="CDD:213141"
gene complement(151161..153761)
/locus_tag="CGSHiEE_00790"
/db_xref="GeneID:5224867"
CDS complement(151161..153761)
/locus_tag="CGSHiEE_00790"
/note="COG5009 Membrane
carboxypeptidase/penicillin-binding protein"
/codon_start=1
/transl_table=11
/product="penicillin-binding protein 1A"
/protein_id="YP_001290033.1"
/db_xref="GI:148825280"
/db_xref="GeneID:5224867"
/translation="MRIAKLILSTLLTLCILGLVAGGMLYFYLKSELPSVETLRTVEL
QQPMQIYTADGKLIGEVGEQRRIPVKLADVPQRLIDAFLATEDSRFYEHHGLDPIGIA
RALFVAVSNGGASQGASTITQQLARNFFLTPEKTIIRKAREAVLAVEIENTLNKQEIL
ELYLNKIFLGYRSYGVAAAAQTYFGKSLNELTLSEMAIIAGLPKAPSTMNPLYSLKRS
EERRNVVLSRMLDEKYISKEEYDAALKEPIVASYHGAKFEFRADYVTEMVRQEMVRRF
GEENAYTSGYKVFTTVLSKDQDEAQKAVRNNLIDYDMRHGYRGGAPLWQKNEAAWDND
RIVGFLRKLPDSEPFIPAAVIGITKGGADILLASGEKMTLSTNAMRWTGRSNPVKVGE
QIWIRQRANGEWQLGQIPSANSALVSLNSDNGAIEAVVGGFSYEQSKFNRATQSLVQV
GSSIKPFIYAAALEKGLTLSSVLQDSPISIQKLGQKLWQPKNSPDRYDGPMRLRVGLG
QSKNMIAIRAIQTAGIDFTAEFLQRFGFKRDQYFASEALALGAASFTPLEMARAYAVF
DNGGFLIEPYIIEKIQDNTGKELFVANPKIACIECNDIPVIYGETKDKINGFANIPLG
ESALKPTDDSTNGEELDQQPETVPELPELQSNMTALKEDAIDLMAAAKNASSKIEYAP
RVISGELAFLIRSALNTAIYGEQGLDWKGTSWRIAQSIKRSDIGGKTGTTNSSKVAWY
AGFGANLVTTTYVGFDDNKRVLGRREAGAKTAMPAWITYMKTALSDKPERKLTLPPKI
VEKSIDTLTGLLSPNGGRKEYFIVGTEPTRTYLSEMQERGYYVPTELQQRLNSEGNTP
TSAAQPEELF"
misc_feature complement(151164..153689)
/locus_tag="CGSHiEE_00790"
/note="penicillin-binding protein 1a; Provisional; Region:
mrcA; PRK11636"
/db_xref="CDD:183248"
misc_feature complement(153072..153602)
/locus_tag="CGSHiEE_00790"
/note="Transglycosylase; Region: Transgly; pfam00912"
/db_xref="CDD:201501"
misc_feature complement(<152016..152519)
/locus_tag="CGSHiEE_00790"
/note="Penicillin binding protein transpeptidase domain;
Region: Transpeptidase; cl01009"
/db_xref="CDD:207282"
gene 153860..154657
/locus_tag="CGSHiEE_00795"
/db_xref="GeneID:5225652"
CDS 153860..154657
/locus_tag="CGSHiEE_00795"
/note="COG0133 Tryptophan synthase beta chain"
/codon_start=1
/transl_table=11
/product="competence protein A"
/protein_id="YP_001290034.1"
/db_xref="GI:148825281"
/db_xref="GeneID:5225652"
/translation="MQFSLKNYLTLQIGIHRKQGYFDFVWFDDLEQPQSYQIFVNDRD
FKNRFLQQLKTQYQGKTFPLQFVASIPAHLTWSKVLMLPQVLNAQECHQQCKFVIEKE
LPISLDELWFDYRSTPLKQGFRLDVTAIRKSTAQTYLQDFQPFKINVLDVASNAILRA
FQYLLNEQVRSENTLFLFQEDDYCLAICERAQQSQILQSHENLTALYEQFTERFEGQL
EQVFVYQIPSSHTPLSENWQRVETELPFIALGNALWKKDLYQQKVSS"
misc_feature 154007..>154384
/locus_tag="CGSHiEE_00795"
/note="Tfp pilus assembly protein, ATPase PilM [Cell
motility and secretion / Intracellular trafficking and
secretion]; Region: PilM; COG4972"
/db_xref="CDD:34578"
gene 154658..155164
/locus_tag="CGSHiEE_00800"
/db_xref="GeneID:5225653"
CDS 154658..155164
/locus_tag="CGSHiEE_00800"
/note="COG0419 ATPase involved in DNA repair"
/codon_start=1
/transl_table=11
/product="competence protein B"
/protein_id="YP_001290035.1"
/db_xref="GI:148825282"
/db_xref="GeneID:5225653"
/translation="MSMNLLPWRTYQHQNRLRRLAFYIALFILLAINLTLAFSNLIEQ
QKQNLQAQQTSFEQLNQQLYKTAKQIEQLRSAVQVGEILTSIPNEQVKKSLQLLSELP
FQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK"
gene 155161..155682
/locus_tag="CGSHiEE_00805"
/db_xref="GeneID:5225654"
CDS 155161..155682
/locus_tag="CGSHiEE_00805"
/codon_start=1
/transl_table=11
/product="competence protein C"
/protein_id="YP_001290036.1"
/db_xref="GI:148825283"
/db_xref="GeneID:5225654"
/translation="MKAFFNDPFTPFGKWLSQPFYVHGLTFLLLLSAVIFRPVLDYIE
GSSRFHEIENELAVKRSELLHQQKILTSLQQQSESRKLSPELAAQIIPLNKQIQRLAA
RNGLSQHLRWEMGQKPILHLQLTGHFEKTKTFLTALLANSSQLSVSRLQFIKPEDNPL
QTEIIFQLDKETK"
gene 155679..156092
/locus_tag="CGSHiEE_00810"
/db_xref="GeneID:5225655"
CDS 155679..156092
/locus_tag="CGSHiEE_00810"
/note="COG1196 Chromosome segregation ATPases"
/codon_start=1
/transl_table=11
/product="competence protein D"
/protein_id="YP_001290037.1"
/db_xref="GI:148825284"
/db_xref="GeneID:5225655"
/translation="MKHWFFLIILFFMNCSWGQDPFDKTQRNRSQFDNAQTVMEQTEI
ISSDVPNNLCGADENRQAAEIPLNALKLVGVVISKDKAFALLQDQGLQIYSVLEGVDV
AQEGYIVEKINQNNVQFMRKLGEQCDSSEWKKLSF"
misc_feature <155763..156038
/locus_tag="CGSHiEE_00810"
/note="Pilus assembly protein, PilP; Region: PilP;
pfam04351"
/db_xref="CDD:146799"
gene 156102..157439
/locus_tag="CGSHiEE_00815"
/db_xref="GeneID:5225656"
CDS 156102..157439
/locus_tag="CGSHiEE_00815"
/note="COG4796 Type II secretory pathway, component HofQ"
/codon_start=1
/transl_table=11
/product="competence protein E"
/protein_id="YP_001290038.1"
/db_xref="GI:148825285"
/db_xref="GeneID:5225656"
/translation="MKKYFLKCGYFLVCFCLPLIVFANPKTDNECFFIRLSQAPLAQT
LEQLAFQQDVNLVMGERLEGNISLKLNNIDMPRLLKIIAKSKHLTLNKDDGVYYLNGS
QSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSSAGSITFDDRSN
LLVIQDEPRFVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENA
RRVAGSLTGNSFENIADNLNVNFATTTTPAGSIALQVAKINGRLLDLELSALERENNV
EIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAVLGLEVTPHISKDNN
ILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSED
KVPLLGDIPVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK"
misc_feature 156186..157388
/locus_tag="CGSHiEE_00815"
/note="type IV pilus secretin (or competence protein)
PilQ; Region: IV_pilus_PilQ; TIGR02515"
/db_xref="CDD:211746"
misc_feature 156465..156653
/locus_tag="CGSHiEE_00815"
/note="Bacterial type II/III secretion system short
domain; Region: Secretin_N; pfam03958"
/db_xref="CDD:202830"
misc_feature 156906..157388
/locus_tag="CGSHiEE_00815"
/note="Bacterial type II and III secretion system protein;
Region: Secretin; pfam00263"
/db_xref="CDD:201120"
gene 157452..158138
/gene="recR"
/locus_tag="CGSHiEE_00820"
/db_xref="GeneID:5225422"
CDS 157452..158138
/gene="recR"
/locus_tag="CGSHiEE_00820"
/note="COG1040 Predicted amidophosphoribosyltransferases"
/codon_start=1
/transl_table=11
/product="competence protein F"
/protein_id="YP_001290039.1"
/db_xref="GI:148825286"
/db_xref="GeneID:5225422"
/translation="MNFFNFRCIHCRGNLHIAKNGLCSGCQKQIKSFPYCGHCGAELQ
YYAQHCGNCLKQEPSWDKMVIIGHYIEPLSILIHRFKFQNQFWIDRTLARLLYLAVRD
AKRTHQLKLPEAIIPVPLYHFRQWRRGYNQADLLSRQLSRWLDIPNLSNIVKRVKHTY
TQRGLSAKDRRQNLKNAFSLVVSKNEFPYRRVALVDDVITTGSTLNEISKLLRKLGVE
EIQVWGLARA"
misc_feature 157518..158132
/gene="recR"
/locus_tag="CGSHiEE_00820"
/note="comF family protein; Region: comF; TIGR00201"
/db_xref="CDD:161762"
misc_feature 157785..>158117
/gene="recR"
/locus_tag="CGSHiEE_00820"
/note="Phosphoribosyl transferase (PRT)-type I domain;
Region: PRTases_typeI; cd06223"
/db_xref="CDD:206754"
misc_feature order(157806..157808,157833..157835,158037..158045,
158049..158063)
/gene="recR"
/locus_tag="CGSHiEE_00820"
/note="active site"
/db_xref="CDD:206754"
gene 158214..158810
/locus_tag="CGSHiEE_00825"
/db_xref="GeneID:5225423"
CDS 158214..158810
/locus_tag="CGSHiEE_00825"
/note="cytoplasmic protein that may be involved in the
utilization of double-stranded DNA as a carbon source"
/codon_start=1
/transl_table=11
/product="putative DNA uptake protein"
/protein_id="YP_001290040.1"
/db_xref="GI:148825287"
/db_xref="GeneID:5225423"
/translation="MEQATQQIAISDAAQAHFRKLLDTQEEGTNIRIFVVNPGTPNAE
CGVSYCPPNAVEESDIEMKYNTFSAFIDEVSLPFLEEAEIDYVTEELGAQLTLKAPNA
KMRKVADDAPLIERVEYVIQTQINPQLANHGGRITLIEITEDGYAVLQFGGGCNGCSM
VDVTLKDGVEKQLVSLFPNELKGAKDITEHQRGEHSYY"
misc_feature 158223..158522
/locus_tag="CGSHiEE_00825"
/note="Fe-S cluster assembly scaffold protein
[Posttranslational modification, protein turnover,
chaperones]; Region: sufA; COG0316"
/db_xref="CDD:30664"
misc_feature 158232..158807
/locus_tag="CGSHiEE_00825"
/note="Fe/S biogenesis protein NfuA; Provisional; Region:
PRK11190"
/db_xref="CDD:183027"
misc_feature 158523..158801
/locus_tag="CGSHiEE_00825"
/note="Thioredoxin-like proteins and domains
[Posttranslational modification, protein turnover,
chaperones]; Region: COG0694"
/db_xref="CDD:31038"
gene 158877..159671
/gene="nudC"
/locus_tag="CGSHiEE_00830"
/db_xref="GeneID:5225424"
CDS 158877..159671
/gene="nudC"
/locus_tag="CGSHiEE_00830"
/note="can catalyze hydrolysis of broad range of
dinucleotide pyrophosphates but prefers reduced form of
NADH; requires divalent metal ions such as magnesium and
manganese and produces two mononucleoside 5'-phosphates"
/codon_start=1
/transl_table=11
/product="NADH pyrophosphatase"
/protein_id="YP_001290041.1"
/db_xref="GI:148825288"
/db_xref="GeneID:5225424"
/translation="MKILQQDDFGYWLLTQGSNLYLVNNELPFGIAKDIDLEGLQAMQ
IGEWKNHPLWLVAEQESDEREYVSLRNLLSLPEDEFHILSRGVEINHFLKTHKFCGKC
GHKTQQTQDELAVQCIHCGYQTYPVICPSIIVAVRRGHEILLANHKRHYSPNGGIYTT
LAGFVEVGETFEQAVQREVFEETGISIKNLRYFGSQPWAFPNSQMVGFLADYESGEIT
LQESEIHDAQWFSYDQPLPELPPTGTIARKLIHVTLELCKAEHKCD"
misc_feature 158877..159647
/gene="nudC"
/locus_tag="CGSHiEE_00830"
/note="NADH pyrophosphatase; Reviewed; Region: nudC;
PRK00241"
/db_xref="CDD:178944"
misc_feature 158904..159152
/gene="nudC"
/locus_tag="CGSHiEE_00830"
/note="NADH pyrophosphatase-like rudimentary NUDIX domain;
Region: NUDIX-like; pfam09296"
/db_xref="CDD:204191"
misc_feature 159156..159251
/gene="nudC"
/locus_tag="CGSHiEE_00830"
/note="NADH pyrophosphatase zinc ribbon domain; Region:
zf-NADH-PPase; pfam09297"
/db_xref="CDD:204192"
misc_feature 159264..159641
/gene="nudC"
/locus_tag="CGSHiEE_00830"
/note="NADH pyrophosphatase, a member of the Nudix
hydrolase superfamily, catalyzes the cleavage of NADH into
reduced nicotinamide mononucleotide (NMNH) and AMP. Like
other members of the Nudix family, it requires a divalent
cation, such as Mg2+ or Mn2+, for...; Region:
NADH_pyrophosphatase; cd03429"
/db_xref="CDD:72887"
misc_feature order(159267..159269,159360..159368,159468..159470,
159477..159479,159483..159485,159489..159491)
/gene="nudC"
/locus_tag="CGSHiEE_00830"
/note="putative NADH binding site [chemical binding];
other site"
/db_xref="CDD:72887"
misc_feature order(159363..159368,159372..159374,159408..159410,
159417..159422,159468..159470,159477..159479,
159483..159485,159489..159491)
/gene="nudC"
/locus_tag="CGSHiEE_00830"
/note="putative active site [active]"
/db_xref="CDD:72887"
misc_feature 159363..159431
/gene="nudC"
/locus_tag="CGSHiEE_00830"
/note="nudix motif; other site"
/db_xref="CDD:72887"
misc_feature order(159408..159410,159417..159422,159543..159545)
/gene="nudC"
/locus_tag="CGSHiEE_00830"
/note="putative metal binding site [ion binding]; other
site"
/db_xref="CDD:72887"
gene 159707..160297
/locus_tag="CGSHiEE_00835"
/db_xref="GeneID:5225425"
CDS 159707..160297
/locus_tag="CGSHiEE_00835"
/note="COG3068 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290042.1"
/db_xref="GI:148825289"
/db_xref="GeneID:5225425"
/translation="MRNPIHKRLENLDSWQHLTFMAALCERMAPNFKLFCQMNELSVE
TKTYQNILNLVWEYLTIKDVKINFENQLEKLESIIPDVNDYDSFGVVPALDACQALAE
ILHAIIAGETLEKAVEISLISLGTVRALLETETGRDWSESKLKENEDIQTELDVQWQV
YRLLKECEKRDIELILALKNEIRTEGISNIGIEFHQ"
misc_feature 159707..160288
/locus_tag="CGSHiEE_00835"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG3068"
/db_xref="CDD:32882"
gene 160437..160709
/gene="nudC"
/locus_tag="CGSHiEE_00840"
/db_xref="GeneID:5225426"
CDS 160437..160709
/gene="nudC"
/locus_tag="CGSHiEE_00840"
/note="COG0776 Bacterial nucleoid DNA-binding protein"
/codon_start=1
/transl_table=11
/product="NADH pyrophosphatase"
/protein_id="YP_001290043.1"
/db_xref="GI:148825290"
/db_xref="GeneID:5225426"
/translation="MNKTDLIDAIANAAELNKKQAKAALEATLDAITASLKEGEPVQL
IGFGTFKVNERAARTGRNPQTGAEIQIAASKVPAFVSGKALKDAIK"
misc_feature 160440..160700
/gene="nudC"
/locus_tag="CGSHiEE_00840"
/note="Integration host factor (IHF) and HU are small
heterodimeric members of the DNABII protein family that
bind and bend DNA, functioning as architectural factors in
many cellular processes including transcription,
site-specific recombination, and...; Region: HU_IHF;
cd00591"
/db_xref="CDD:29683"
misc_feature order(160440..160445,160452..160454,160461..160463,
160473..160475,160515..160517,160524..160529,
160536..160541,160551..160565,160572..160577,
160590..160592,160656..160661,160671..160673,
160677..160679,160698..160700)
/gene="nudC"
/locus_tag="CGSHiEE_00840"
/note="IHF dimer interface [polypeptide binding]; other
site"
/db_xref="CDD:29683"
misc_feature order(160440..160448,160512..160514,160557..160559,
160563..160565,160569..160574,160581..160583,
160593..160595,160599..160604,160608..160610,
160617..160628,160656..160658,160668..160670,
160674..160676,160683..160685)
/gene="nudC"
/locus_tag="CGSHiEE_00840"
/note="IHF - DNA interface [nucleotide binding]; other
site"
/db_xref="CDD:29683"
gene 160822..162654
/locus_tag="CGSHiEE_00845"
/db_xref="GeneID:5226253"
CDS 160822..162654
/locus_tag="CGSHiEE_00845"
/EC_number="2.6.1.16"
/note="Catalyzes the first step in hexosamine metabolism,
converting fructose-6P into glucosamine-6P using glutamine
as a nitrogen source"
/codon_start=1
/transl_table=11
/product="glucosamine--fructose-6-phosphate
aminotransferase"
/protein_id="YP_001290044.1"
/db_xref="GI:148825291"
/db_xref="GeneID:5226253"
/translation="MCGIVGAVAQRDVAEILINGLHRLEYRGYDSAGVAVINKQNELQ
RIRCLGKVKALDEAVSEKPLIGGTGIAHTRWATHGEPSETNAHPHSSGTFAVVHNGII
ENHEELRELLKSRGYVFLSQTDTEVIAHLVEWEMRSTDSLLEAVQKSVKQLTGAYGMV
VMDSRHPEHLVAARSGSPLVIGLGIGENFLASDQLALLSVTRRFIFLEEGDIAEITRR
TVDIYDTHGNKAKREIHESNLENDAAEKGKFRHFMQKEIYEQPTALINTMEGRINHEN
VIVDSIGNGAKGILEKVEHIQIVACGTSYNAGMVARYWFESLAGVSCDVEIASEFRYR
KFVTRPNSLLITLSQSGETADTLAALRLAKEKGYMAALTICNVAGSSLVRESDLAFMT
RAGVEVGVASTKAFTTQLAALLMLVTALGKVKGHISVEKEREIIKAMQSLPAEIEKAL
AFDSEIEALAEDFAEKHHALFLGRGVFYPIAVEASLKLKEISYIHAEAYAAGELKHGP
LALIDADMPVIVVAPNNELLEKVKSNIEEVRARGGQLYVFADKEAGFTPSEGMKIITM
PKVNDIVAPIFYTIPMQLLSYYVALIKGTDVDQPRNLAKSVTVE"
misc_feature 160822..162651
/locus_tag="CGSHiEE_00845"
/note="glucosamine--fructose-6-phosphate aminotransferase;
Reviewed; Region: PRK00331"
/db_xref="CDD:178980"
misc_feature 160825..161466
/locus_tag="CGSHiEE_00845"
/note="Glutamine amidotransferases class-II
(Gn-AT)_GFAT-type. This domain is found at the N-terminus
of glucosamine-6P synthase (GlmS, or GFAT in humans). The
glutaminase domain catalyzes amide nitrogen transfer from
glutamine to the appropriate substrate. In...; Region:
GFAT; cd00714"
/db_xref="CDD:48478"
misc_feature order(160825..160827,160900..160902,161041..161046,
161050..161055,161080..161082,161116..161121,
161191..161196)
/locus_tag="CGSHiEE_00845"
/note="glutaminase active site [active]"
/db_xref="CDD:48478"
misc_feature 161704..162084
/locus_tag="CGSHiEE_00845"
/note="SIS (Sugar ISomerase) domain repeat 1 found in
Glucosamine 6-phosphate synthase (GlmS) and
Glucosamine-6-phosphate deaminase (GlmD). The SIS domain
is found in many phosphosugar isomerases and phosphosugar
binding proteins. GlmS contains a N-terminal...; Region:
SIS_GlmS_GlmD_1; cd05008"
/db_xref="CDD:88405"
misc_feature order(161722..161727,161755..161760,161767..161772,
161791..161793,161797..161799,161809..161811,
161818..161820,161884..161886)
/locus_tag="CGSHiEE_00845"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:88405"
misc_feature order(161728..161733,161863..161871)
/locus_tag="CGSHiEE_00845"
/note="active site"
/db_xref="CDD:88405"
misc_feature 162184..162645
/locus_tag="CGSHiEE_00845"
/note="SIS (Sugar ISomerase) domain repeat 2 found in
Glucosamine 6-phosphate synthase (GlmS) and
Glucosamine-6-phosphate deaminase (GlmD). The SIS domain
is found in many phosphosugar isomerases and phosphosugar
binding proteins. GlmS contains a N-terminal...; Region:
SIS_GlmS_GlmD_2; cd05009"
/db_xref="CDD:88406"
misc_feature order(162244..162246,162286..162288,162298..162300,
162304..162306,162310..162312,162316..162318,
162328..162330,162334..162342,162346..162357,
162406..162411,162421..162423,162427..162432,
162622..162627,162640..162642)
/locus_tag="CGSHiEE_00845"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:88406"
misc_feature order(162280..162282,162289..162291)
/locus_tag="CGSHiEE_00845"
/note="active site"
/db_xref="CDD:88406"
gene complement(162706..163239)
/locus_tag="CGSHiEE_00850"
/db_xref="GeneID:5226254"
CDS complement(162706..163239)
/locus_tag="CGSHiEE_00850"
/note="disulfide oxidoreductase; integral membrane
protein; required for perioplasmic disulfide bond
formation; oxidizes DsbA protein"
/codon_start=1
/transl_table=11
/product="disulfide bond formation protein B"
/protein_id="YP_001290045.1"
/db_xref="GI:148825292"
/db_xref="GeneID:5226254"
/translation="MLALLKQFSEKRFVWFLLAFSSLALESTALYFQYGMGLQPCVLC
VYERLAMIGLFVAGIIALLQPLAFILRLIALALGLFSSIKGLLISFRHLDLQMNPAPW
KQCEFIPNFPETLPFHQWFPFIFNPTGSCNESQWSLFGLTMVQWLVVIFSLYVVILTL
LLIAQVIKTRKQRRLFN"
misc_feature complement(162709..163239)
/locus_tag="CGSHiEE_00850"
/note="disulfide bond formation protein B; Provisional;
Region: PRK01749"
/db_xref="CDD:179331"
misc_feature complement(163249..164794)
/note="potential frameshift: common BLAST hit:
gi|30995374|ref|NP_438588.2| Na+/H+ antiporter
[Haemophilus influenzae Rd KW20]"
gene 164921..165646
/locus_tag="CGSHiEE_00865"
/db_xref="GeneID:5226255"
CDS 164921..165646
/locus_tag="CGSHiEE_00865"
/note="Multifunctional regulator of fatty acid metabolism"
/codon_start=1
/transl_table=11
/product="fatty acid metabolism regulator"
/protein_id="YP_001290046.1"
/db_xref="GI:148825293"
/db_xref="GeneID:5226255"
/translation="MQNNNDILKAQSPAALAEEYIVKSIWQDVFPAGSNLPSERDLAD
KIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNIWDAAGPNIIETLIALDMQSAPLI
IDNMLSLRSKMSESYIYEAVKNSPQKSTALFAELEQLQNTAQDYTEFDYQLFRQFTVV
ANKPFYRLIFNSLKGVYQRIGLLFFKEKTHRELTKQFYLEMQQICLEGNADAVVDCIR
KHNLRSSTYWKAILERLPQNLSD"
misc_feature 164939..165643
/locus_tag="CGSHiEE_00865"
/note="fatty acid metabolism transcriptional regulator
FadR; Region: fadR_gamma; TIGR02812"
/db_xref="CDD:163028"
misc_feature 164975..165151
/locus_tag="CGSHiEE_00865"
/note="Winged helix-turn-helix (WHTH) DNA-binding domain
of the GntR family of transcriptional regulators; Region:
WHTH_GntR; cd07377"
/db_xref="CDD:153418"
misc_feature order(165029..165031,165035..165040,165062..165076,
165080..165085,165092..165094,165122..165127,
165131..165142)
/locus_tag="CGSHiEE_00865"
/note="DNA-binding site [nucleotide binding]; DNA binding
site"
/db_xref="CDD:153418"
misc_feature 165149..165640
/locus_tag="CGSHiEE_00865"
/note="FadR C-terminal domain; Region: FadR_C; pfam07840"
/db_xref="CDD:116452"
gene complement(165691..167058)
/gene="pssA"
/locus_tag="CGSHiEE_00870"
/db_xref="GeneID:5226256"
CDS complement(165691..167058)
/gene="pssA"
/locus_tag="CGSHiEE_00870"
/EC_number="2.7.8.8"
/note="catalyzes de novo synthesis of phosphatidylserine
from CDP-diacylglycerol and L-serine which leads
eventually to the production of phosphatidylethanolamine;
bounds to the ribosome"
/codon_start=1
/transl_table=11
/product="phosphatidylserine synthase"
/protein_id="YP_001290047.1"
/db_xref="GI:148825294"
/db_xref="GeneID:5226256"
/translation="MLINKTKRAEQNLNNLPFLALQAEQIEFLGSSAEFKTQIIELIR
NAKKRIYVTALYWQKDEAGQEILDEIYRVKQENPHLDVKILIDWHRAQRNLLGAEKSA
TNADWYCEQRQTYQLPNDPNMFFGVPINTREVFGVLHVKGFVFDDTVLYSGASINNVY
LHQFEKYRYDRYQKITHAELADSMVNFINDYLLDFSAVYPLDVTNRPRTKEIRGNIRA
YRKDLAQNGEYSLKSAVKLPNVLSVSPLFGLGASGNELNQVIEDLFLQVQEKLVICTP
YFNFPRTLQHKIATLLENGKRVEIIVGDKVANDFYIPPEQPFKMAGALPYLYESNLRR
FCEKFETQIESGQLVVRLWRDGDNTYHLKGVWVDDRYILLTGNNLNPRAWRLDAENGL
LIYDPQQQLLAQVEKEQNQIRQHTKVLKHYTELEELNQYPEPVQKLLKKFARIKADKL
VKMIL"
misc_feature complement(165694..167058)
/gene="pssA"
/locus_tag="CGSHiEE_00870"
/note="phosphatidylserine synthase; Provisional; Region:
pssA; PRK09428"
/db_xref="CDD:181848"
misc_feature complement(166486..167013)
/gene="pssA"
/locus_tag="CGSHiEE_00870"
/note="Catalytic domain, repeat 1, of phosphatidylserine
synthases from gram-negative bacteria; Region:
PLDc_PSS_G_neg_1; cd09134"
/db_xref="CDD:197232"
misc_feature complement(order(166486..166488,166498..166500,
166507..166512,166522..166524,166534..166536,
166540..166542,166546..166560,166600..166602,
166606..166608,166636..166656,166666..166680,
166975..166977,166981..166983))
/gene="pssA"
/locus_tag="CGSHiEE_00870"
/note="domain interface [polypeptide binding]; other site"
/db_xref="CDD:197232"
misc_feature complement(order(166549..166551,166594..166596,
166600..166602,166636..166638,166642..166644))
/gene="pssA"
/locus_tag="CGSHiEE_00870"
/note="putative active site [active]"
/db_xref="CDD:197232"
misc_feature complement(166642..166644)
/gene="pssA"
/locus_tag="CGSHiEE_00870"
/note="catalytic site [active]"
/db_xref="CDD:197232"
misc_feature complement(165694..166338)
/gene="pssA"
/locus_tag="CGSHiEE_00870"
/note="Catalytic domain, repeat 2, of phosphatidylserine
synthases from gram-negative bacteria; Region:
PLDc_PSS_G_neg_2; cd09136"
/db_xref="CDD:197234"
misc_feature complement(order(165823..165828,165835..165837,
165847..165849,165856..165858,165874..165876,
165880..165903,165913..165915,165931..165942,
165973..165987,166312..166314,166318..166338))
/gene="pssA"
/locus_tag="CGSHiEE_00870"
/note="domain interface [polypeptide binding]; other site"
/db_xref="CDD:197234"
misc_feature complement(order(165892..165894,165925..165927,
165931..165933,165970..165972,165976..165978))
/gene="pssA"
/locus_tag="CGSHiEE_00870"
/note="putative active site [active]"
/db_xref="CDD:197234"
misc_feature complement(165976..165978)
/gene="pssA"
/locus_tag="CGSHiEE_00870"
/note="catalytic site [active]"
/db_xref="CDD:197234"
gene 167204..167527
/locus_tag="CGSHiEE_00875"
/db_xref="GeneID:5226257"
CDS 167204..167527
/locus_tag="CGSHiEE_00875"
/note="COG1502
Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi
n synthases and related enzymes"
/codon_start=1
/transl_table=11
/product="rRNA methylase"
/protein_id="YP_001290048.1"
/db_xref="GI:148825295"
/db_xref="GeneID:5226257"
/translation="MNDKRKPSFQSAGKTFQERSVGEKYLEKPSQNRPHFNDKFNGNR
NEKSRFSRDKQEVKETKITQLSLSRAPSNKNVEKPKVQVTIKTTGTIYKTKEKKNGCT
FSSCA"
gene 167556..168260
/locus_tag="CGSHiEE_00880"
/db_xref="GeneID:5225342"
CDS 167556..168260
/locus_tag="CGSHiEE_00880"
/note="COG0566 rRNA methylases"
/codon_start=1
/transl_table=11
/product="rRNA methylase"
/protein_id="YP_001290049.1"
/db_xref="GI:148825296"
/db_xref="GeneID:5225342"
/translation="MKVYGENACLALFAERPESIVRLWATVQMSHKIGEVLSYLAENK
KAYHVVDSEELARVSGTEHHGGICLLVKKPRAFTLQGYLDIPRNEDCLVLLDNVNNAQ
NIGGVLRTCAYFGVKNIVADNVENLYSAASMRVAEGGAEYIRVLETDDIDSALMQLRK
SGYQVIHVSHNKQGDPLDKVRLKNKVVFVLSESSTESLATPEDTQVRLTLASPIKSGL
NIAVNAGVLLAKWYFR"
misc_feature 167556..168251
/locus_tag="CGSHiEE_00880"
/note="rRNA methylase, putative, group 3; Region:
rRNA_methyl_3; TIGR00186"
/db_xref="CDD:129290"
misc_feature 167562..167774
/locus_tag="CGSHiEE_00880"
/note="RNA 2'-O ribose methyltransferase substrate
binding; Region: SpoU_sub_bind; smart00967"
/db_xref="CDD:198035"
misc_feature 167832..168239
/locus_tag="CGSHiEE_00880"
/note="SpoU rRNA Methylase family; Region: SpoU_methylase;
cl00362"
/db_xref="CDD:212202"
gene complement(168292..168990)
/gene="pssA"
/locus_tag="CGSHiEE_00885"
/db_xref="GeneID:5225343"
CDS complement(168292..168990)
/gene="pssA"
/locus_tag="CGSHiEE_00885"
/EC_number="2.7.8.8"
/note="COG4123 Predicted O-methyltransferase"
/codon_start=1
/transl_table=11
/product="phosphatidylserine synthase"
/protein_id="YP_001290050.1"
/db_xref="GI:148825297"
/db_xref="GeneID:5225343"
/translation="MSGFTFKQFHINQNSCAMKVSTDGILLGAWADVKHCKNILDMGS
GTGLLALMLAQRTEENCQIQAVELDPIAAKQAQENINNSVWKNRIQLIQTDIQHFLQT
TAQTFDLIVANPPYFEQGIACKNEERELARYTKQSHLNWLEWAATRLSENGRISFVLP
YDAGKTLIKSTALFCIKQTNVITKIGKTPQRMLLTFAKQPQVLMQDQLVIYDADNQYT
EAFIELTKDFYLKF"
misc_feature complement(168295..168990)
/gene="pssA"
/locus_tag="CGSHiEE_00885"
/note="Predicted O-methyltransferase [General function
prediction only]; Region: COG4123"
/db_xref="CDD:33880"
misc_feature complement(168514..168879)
/gene="pssA"
/locus_tag="CGSHiEE_00885"
/note="S-adenosylmethionine-dependent methyltransferases
(SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
that use S-adenosyl-L-methionine (SAM or AdoMet) as a
substrate for methyltransfer, creating the product
S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
cd02440"
/db_xref="CDD:100107"
misc_feature complement(order(168652..168654,168703..168711,
168787..168792,168847..168867))
/gene="pssA"
/locus_tag="CGSHiEE_00885"
/note="S-adenosylmethionine binding site [chemical
binding]; other site"
/db_xref="CDD:100107"
gene 169060..170379
/locus_tag="CGSHiEE_00890"
/db_xref="GeneID:5225344"
CDS 169060..170379
/locus_tag="CGSHiEE_00890"
/note="facilitates an early step in the assembly of the
50S subunit of the ribosome"
/codon_start=1
/transl_table=11
/product="ATP-dependent RNA helicase SrmB"
/protein_id="YP_001290051.1"
/db_xref="GI:148825298"
/db_xref="GeneID:5225344"
/translation="MNLSQFEQFDLSPELLKALEKKGYSRPTAIQMEAIPAAMEERDV
LGSAPTGTGKTAAFLLPALQHLLDYPRRKPGPPRILVLTPTRELAMQVAEQAEELAQF
THLNIATITGGVAYQNHGDVFNTNQDLVVATPGRLLQYIKEENFDCRSVEMLIFDEAD
RMLQMGFGQDAEKIAAETRWRKQTLLFSATLEGELLVDFAERLLNDPVKVDAEPSRRE
RKKINQWYYHADSNEHKIKLLARFIETEEVTRGIVFVRRREDARELSETLRKRGIRSA
YLEGEMAQTQRNNAIDKLKSGIVTVLVATDVAARGIDIDDVSHVMNFDLPYSADTYLH
RIGRTARAGKKGTAVSFVEAHDYKLLGKIKRYTEEILKARILAGLEPRTKPPKDGEVK
SVSKKQKARIKEKREDKKKTEAKKKVKLRHKDTKNIGKRRKPSNSNV"
misc_feature 169072..170373
/locus_tag="CGSHiEE_00890"
/note="ATP-dependent RNA helicase SrmB; Provisional;
Region: PRK11192"
/db_xref="CDD:183029"
misc_feature 169075..169689
/locus_tag="CGSHiEE_00890"
/note="DEAD-box helicases. A diverse family of proteins
involved in ATP-dependent RNA unwinding, needed in a
variety of cellular processes including splicing, ribosome
biogenesis and RNA degradation. The name derives from the
sequence of the Walker B motif; Region: DEADc; cd00268"
/db_xref="CDD:28928"
misc_feature 169210..169224
/locus_tag="CGSHiEE_00890"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:28928"
misc_feature 169528..169539
/locus_tag="CGSHiEE_00890"
/note="Mg++ binding site [ion binding]; other site"
/db_xref="CDD:28928"
misc_feature 169621..169629
/locus_tag="CGSHiEE_00890"
/note="motif III; other site"
/db_xref="CDD:28928"
misc_feature 169720..170112
/locus_tag="CGSHiEE_00890"
/note="Helicase superfamily c-terminal domain; associated
with DEXDc-, DEAD-, and DEAH-box proteins, yeast
initiation factor 4A, Ski2p, and Hepatitis C virus NS3
helicases; this domain is found in a wide variety of
helicases and helicase related proteins; may...; Region:
HELICc; cd00079"
/db_xref="CDD:28960"
misc_feature order(169825..169836,169894..169899,169972..169980)
/locus_tag="CGSHiEE_00890"
/note="nucleotide binding region [chemical binding]; other
site"
/db_xref="CDD:28960"
misc_feature order(169996..169998,170059..170061,170071..170073,
170080..170082)
/locus_tag="CGSHiEE_00890"
/note="ATP-binding site [chemical binding]; other site"
/db_xref="CDD:28960"
gene complement(170413..171792)
/locus_tag="CGSHiEE_00895"
/db_xref="GeneID:5225345"
CDS complement(170413..171792)
/locus_tag="CGSHiEE_00895"
/codon_start=1
/transl_table=11
/product="putative protease"
/protein_id="YP_001290052.1"
/db_xref="GI:148825299"
/db_xref="GeneID:5225345"
/translation="MTTQFKPELLSPAGSLKNMRYAFAYGADAVYAGQPRYSLRVRNN
EFNHANLKIGIDEAHSLGKKFYVVVNIAPHNSKLKTFIKDLQPVIDMKPDALIMSDPG
LIMLVRENFPNIDIHLSVQANAVNWATVKFWKQMGLTRVILSRELSIDEIAEIRQQVP
DIELEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYKMEEGTTDEVGNIV
PKIDPAQQIEVKNVAPTLGEGAVTDKVFLYTESQKPDEQMTAFEDEHGTYFMNSKDLR
AVQHVEKLTALGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDESLMDTLES
LAHRGYTEGFLRRHTHDEYQNYEYGYSISDRQQFVGEFTGKRNEQGMAEVAVKNKFLL
GDNVEMMTPQGNINFKIEKMLNRKNETVDAALGDGHFVFLNVPQDINLNYALLMRNLV
NTNTRNPHC"
misc_feature complement(170446..171780)
/locus_tag="CGSHiEE_00895"
/note="putative protease; Provisional; Region: PRK15452"
/db_xref="CDD:185349"
misc_feature complement(170743..171561)
/locus_tag="CGSHiEE_00895"
/note="Peptidase family U32; Region: Peptidase_U32;
pfam01136"
/db_xref="CDD:201619"
gene 171848..171949
/locus_tag="CGSHiEE_00900"
/db_xref="GeneID:5225346"
CDS 171848..171949
/locus_tag="CGSHiEE_00900"
/note="COG0826 Collagenase and related proteases"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290053.1"
/db_xref="GI:148825300"
/db_xref="GeneID:5225346"
/translation="MGYCRENIWLVKESAVKFLVEFYVKFNRLIDCI"
gene complement(171961..173268)
/locus_tag="CGSHiEE_00905"
/db_xref="GeneID:5225347"
CDS complement(171961..173268)
/locus_tag="CGSHiEE_00905"
/note="COG0477 Permeases of the major facilitator
superfamily"
/codon_start=1
/transl_table=11
/product="ATP-dependent RNA helicase SrmB"
/protein_id="YP_001290054.1"
/db_xref="GI:148825301"
/db_xref="GeneID:5225347"
/translation="MNTQNSLKQVTTATMVGTAIEYFDNYIYAMAAVLVFNHQFFHVA
DPLSGQIAALSTLALTFIARPLGAILFGHFGDRFGRKNTFVMSLLLMGVSTVVIGLLP
TYDSIGIWATILLCLCRIGQGIGLGGEWGGAALVAVENAPEEGKRGWYGTFPQLGAPL
GLLLANGVFLGITAIFGQEAMTEWAWRIPFLSSVILVAIGLYVRLKLTEAPIFLAALN
KPQPKRLPMLEVVTTYFKPFFLGMLICIAGYVLFYIMIAFSQIYAKSAPTVSEAGYAM
GLGLSPQIFTALLMTSAVSLAITIAVSGKYIDKIGRRIWLIWTTVGVAIFGLSLPLFL
ENGTTTSLFWFLFIGMGLIGMGYGPLASFLPELFPTHARYSGASLTYNIAGLFGASVA
AIIALPLNAHYGLKGVGIYLTLNAVLSLVGLWFISETKDKLLS"
misc_feature complement(172009..173220)
/locus_tag="CGSHiEE_00905"
/note="metabolite-proton symporter; Region: 2A0106;
TIGR00883"
/db_xref="CDD:188094"
misc_feature complement(171991..173100)
/locus_tag="CGSHiEE_00905"
/note="The Major Facilitator Superfamily (MFS) is a large
and diverse group of secondary transporters that includes
uniporters, symporters, and antiporters. MFS proteins
facilitate the transport across cytoplasmic or internal
membranes of a variety of...; Region: MFS; cd06174"
/db_xref="CDD:119392"
misc_feature complement(order(172102..172104,172111..172116,
172123..172128,172138..172143,172174..172176,
172183..172188,172198..172200,172207..172212,
172219..172221,172369..172371,172381..172383,
172390..172392,172402..172404,172414..172416,
172489..172491,172498..172503,172510..172515,
172522..172524,172759..172761,172777..172782,
172816..172821,172855..172857,172864..172869,
172876..172881,172888..172893,173053..173058,
173062..173067,173077..173079,173086..173091,
173098..173100))
/locus_tag="CGSHiEE_00905"
/note="putative substrate translocation pore; other site"
/db_xref="CDD:119392"
gene complement(173252..173932)
/gene="thiE"
/locus_tag="CGSHiEE_00910"
/db_xref="GeneID:5225337"
CDS complement(173252..173932)
/gene="thiE"
/locus_tag="CGSHiEE_00910"
/EC_number="2.5.1.3"
/note="Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole
monophosphate and 4-amino-5-hydroxymethyl pyrimidine
pyrophosphate to form thiamine monophosphate"
/codon_start=1
/transl_table=11
/product="thiamine-phosphate pyrophosphorylase"
/protein_id="YP_001290055.1"
/db_xref="GI:148825302"
/db_xref="GeneID:5225337"
/translation="MKNIQKILPLYFVAGTQDCRHLGENLSENLLFVLKQALEGGITC
FQFRDKGKFSLEHTPSAQKALAMSCRDLCREYGVPFIVDDNVDLALEIEADGIHVGQS
DMPVQEIRAKTDKPLIIGWSVNRLDEAKIGENLAEIDYFGIGPIFPTQSKENPKPTLG
MAFIQTLRNVGITKPLVAIGGVKLAHVKTLREFGADGVAVITAITHADNVQAATKALR
EASDEYAK"
misc_feature complement(173276..173905)
/gene="thiE"
/locus_tag="CGSHiEE_00910"
/note="Thiamine monophosphate synthase (TMP
synthase)/TenI. TMP synthase catalyzes an important step
in the thiamine biosynthesis pathway, the substitution of
the pyrophosphate of 2-methyl-4-amino-5-
hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-;
Region: TMP_TenI; cd00564"
/db_xref="CDD:73367"
misc_feature complement(order(173327..173338,173390..173392,
173402..173404,173480..173482,173486..173488,
173507..173509,173513..173515,173567..173569,
173639..173641,173789..173791,173795..173797,
173894..173896,173900..173902))
/gene="thiE"
/locus_tag="CGSHiEE_00910"
/note="thiamine phosphate binding site [chemical binding];
other site"
/db_xref="CDD:73367"
misc_feature complement(order(173327..173332,173390..173392,
173477..173482,173486..173488,173567..173569,
173624..173626,173681..173686,173783..173785,
173789..173791,173795..173797))
/gene="thiE"
/locus_tag="CGSHiEE_00910"
/note="active site"
/db_xref="CDD:73367"
misc_feature complement(order(173477..173479,173567..173569,
173624..173626,173633..173635,173681..173686,
173783..173785,173789..173791))
/gene="thiE"
/locus_tag="CGSHiEE_00910"
/note="pyrophosphate binding site [ion binding]; other
site"
/db_xref="CDD:73367"
gene complement(173943..174752)
/locus_tag="CGSHiEE_00915"
/db_xref="GeneID:5225338"
CDS complement(173943..174752)
/locus_tag="CGSHiEE_00915"
/EC_number="2.7.4.7"
/note="catalyzes the formation of
4-amino-2-methyl-5-diphosphomethylpyrimidine"
/codon_start=1
/transl_table=11
/product="phosphomethylpyrimidine kinase"
/protein_id="YP_001290056.1"
/db_xref="GI:148825303"
/db_xref="GeneID:5225338"
/translation="MSNVKQVLTIAGSDSGGGAGIQADLKTFQMQGVFGTSVITAVTA
QNTLGVFDIHTIPLNTITAQLQAVKNDFQIASCKIGMLGNAEIIECVADFLADKPFGT
LVLDPVMIAKGGAPLLQHQAVSALSQKLLPLADVITPNIPEAEALTGIAIVDDISIQQ
AAKALQKQGAKNVIIKGGHSLNSQSELCQDWVLLADGRHFTLQSPRFNTPHTHGTGCT
FSACLTAELAKGEPLQSAVKTAKDFITAAISHPLNIGQGHGPTNHWAYSRL"
misc_feature complement(174003..174737)
/locus_tag="CGSHiEE_00915"
/note="4-amino-5-hydroxymethyl-2-methyl-pyrimidine
phosphate kinase (HMPP-kinase) catalyzes two consecutive
phosphorylation steps in the thiamine phosphate
biosynthesis pathway, leading to the synthesis of vitamin
B1. The first step is the phosphorylation of...; Region:
HMPP_kinase; cd01169"
/db_xref="CDD:29353"
misc_feature complement(order(174549..174554,174564..174566,
174573..174575,174582..174587,174591..174593,
174597..174602,174615..174629,174636..174638,
174642..174659,174666..174668,174675..174680,
174687..174689,174699..174701,174705..174710,
174714..174716,174735..174737))
/locus_tag="CGSHiEE_00915"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:29353"
misc_feature complement(order(174102..174104,174510..174512,
174618..174620,174681..174683,174717..174719))
/locus_tag="CGSHiEE_00915"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:29353"
misc_feature complement(order(174105..174107,174111..174113,
174225..174227,174324..174326,174435..174437))
/locus_tag="CGSHiEE_00915"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:29353"
gene complement(174745..175536)
/locus_tag="CGSHiEE_00920"
/db_xref="GeneID:5225339"
CDS complement(174745..175536)
/locus_tag="CGSHiEE_00920"
/EC_number="2.7.1.50"
/note="catalyzes the formation of
4-methyl-5-(2-phosphoethyl)-thiazole and ADP from
4-methyl-5-(2-hydroxyethyl)-thiazole and ATP"
/codon_start=1
/transl_table=11
/product="hydroxyethylthiazole kinase"
/protein_id="YP_001290057.1"
/db_xref="GI:148825304"
/db_xref="GeneID:5225339"
/translation="MQSIYLAKIREQNPLIHNITNIVAANFSANGLLALGASPLMSAN
VEEMQEVPKISQALVINIGTLIGKDREAMLQAGKTANEVGIPVVLDPVGVGATSYRRE
TVRQLLAEVKFTLIRGNAGELAAIAGEAWQAKGVDAGKGEVDLKAVAEKVAQRYGCTA
LISGAVDIVSDGTQTATIHNGTPLFPKVTASGCLLSAVCAAFLAVSEGNYFSATLEAC
VAYTIAGERAAQSLTTQVGQFQIRLLDELAALSPETIRQRGRINE"
misc_feature complement(174793..175521)
/locus_tag="CGSHiEE_00920"
/note="4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase
catalyzes the phosphorylation of the hydroxylgroup of Thz.
A reaction that allows cells to recycle Thz into the
thiamine biosynthesis pathway, as an alternative to its
synthesis from cysteine, tyrosine...; Region: THZ_kinase;
cd01170"
/db_xref="CDD:29354"
misc_feature complement(order(175345..175350,175354..175356,
175414..175416,175420..175422,175438..175440,
175450..175452,175468..175470,175474..175476))
/locus_tag="CGSHiEE_00920"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:29354"
misc_feature complement(order(174793..174795,174802..174807,
174811..174819,174823..174828,174970..174981,
175237..175242,175339..175350,175384..175389,
175396..175401,175405..175416,175438..175440,
175447..175452,175456..175473))
/locus_tag="CGSHiEE_00920"
/note="multimerization interface [polypeptide binding];
other site"
/db_xref="CDD:29354"
misc_feature complement(order(174958..174960,174964..174966,
174982..174984,175036..175038,175042..175044,
175048..175050,175171..175173,175180..175182,
175186..175188,175267..175269))
/locus_tag="CGSHiEE_00920"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:29354"
gene complement(175866..176102)
/locus_tag="CGSHiEE_00925"
/db_xref="GeneID:5225340"
CDS complement(175866..176102)
/locus_tag="CGSHiEE_00925"
/note="COG2145 Hydroxyethylthiazole kinase, sugar kinase
family"
/codon_start=1
/transl_table=11
/product="outer membrane opacity protein B"
/protein_id="YP_001290058.1"
/db_xref="GI:148825305"
/db_xref="GeneID:5225340"
/translation="MQADWGHVREKVETYNPNQPEILQEYLNIKTHSNHPRFSIGYDF
GNWRLALDYSHYDRCLENVRFKTHEASFGVRYRF"
misc_feature complement(<175869..175985)
/locus_tag="CGSHiEE_00925"
/note="Porin superfamily. These outer membrane channels
share a beta-barrel structure that differ in strand and
shear number. Classical (gram-negative ) porins are
non-specific channels for small hydrophillic molecules and
form 16 beta-stranded barrels (16,20)...; Region:
OM_channels; cl01155"
/db_xref="CDD:213103"
gene complement(176256..179063)
/locus_tag="CGSHiEE_00930"
/db_xref="GeneID:5225341"
CDS complement(176256..179063)
/locus_tag="CGSHiEE_00930"
/EC_number="2.7.1.50"
/note="COG1530 Ribonucleases G and E"
/codon_start=1
/transl_table=11
/product="ribonuclease E"
/protein_id="YP_001290059.1"
/db_xref="GI:148825306"
/db_xref="GeneID:5225341"
/translation="MKRMLINATQKEELRVALVDGQRLFDLDIESPGHEQKKANIYKG
TITRVEPSLEAAFVDYGAERHGFLPLKEIAREYFPDDYVFQGRPNIRDILTEGQEVIV
QVNKEERGNKGAALTTFVSLAGSYLVFMPNNPRAGGISRRIEGDERTELKEALSSLDV
PDGVGLIVRTAGVGKSPEELQWDLKVLLHHWEAIKQASQSRPAPFLIHQESDVIVRAI
RDYLRRDIGEILIDSPKIFEKAKEHIKLVRPDFINRVKLYQGEVPLFSHYQIESQIES
AFQREVRLPSGGSIVIDVTEALTAIDINSARSTRGGDIEETALNTNLEAADEIARQLR
LRDLGGLVVIDFIDMTPIRHQREVENRIRDAVRPDRARIQISRISRFGLLEMSRQRLS
PSLGESSHHICPRCQGTGKVRDNESLSLSILRLLEEEALKENTKQVHTIVPVQIASYL
LNEKRKAISNIEKRHNVDIIVAPNEAMETPHFSVFRLRDGEEVNELSYNLAKIHCEKD
ENTEESLVSRNIETTAVIEQPAVESAAVALSISEAAPTPVERKSNEPSLLAKIIAKIK
GLFTAKSEENKPKNNRTSRNSNRNQRRSQDRRTSRRPRSENNEAERTEEQVRNVRERN
QRRPRRNLVEESIAESAVNSTPVFEAKEERTEPVTQRRQRRDLRKRVRVEDNETVVEN
NFSTTEKMPEVDVITVQNNDEKPVHQNQRSERQERQRRTPRHLRAANNQRRRRNQEPK
SPMPLFAAVVSPELASGKAWIDYSTVNLPKENHFLSVDELLEQEKTKKGFITPAMGII
VEEKSPDVKPALDFITQPANESVQKKVQESLDRLSSYKPQEVVESIDPAINVDEPETL
EKVSKFVRTYEFNGRLGTISSVPHTKAEMTLAKANDEMPEAFPIRAWQDSRYYFYGKG
AAGHHCAISHVYSEPTRAKSE"
misc_feature complement(177819..179024)
/locus_tag="CGSHiEE_00930"
/note="ribonuclease, Rne/Rng family; Region: RNaseEG;
TIGR00757"
/db_xref="CDD:200047"
misc_feature complement(178692..178970)
/locus_tag="CGSHiEE_00930"
/note="S1_RNase_E: RNase E and RNase G, S1-like
RNA-binding domain. RNase E is an essential
endoribonuclease in the processing and degradation of RNA.
In addition to its role in mRNA degradation, RNase E has
also been implicated in the processing of rRNA, and...;
Region: S1_RNase_E; cd04453"
/db_xref="CDD:88419"
misc_feature complement(order(178767..178769,178779..178781,
178935..178937))
/locus_tag="CGSHiEE_00930"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:88419"
misc_feature complement(order(178695..178697,178725..178730,
178737..178739,178746..178748,178863..178865))
/locus_tag="CGSHiEE_00930"
/note="oligonucleotide binding site [chemical binding];
other site"
/db_xref="CDD:88419"
misc_feature complement(176262..176378)
/locus_tag="CGSHiEE_00930"
/note="Polyribonucleotide phosphorylase C terminal;
Region: PNPase_C; pfam12111"
/db_xref="CDD:152546"
gene 179485..180453
/locus_tag="CGSHiEE_00935"
/db_xref="GeneID:5225312"
CDS 179485..180453
/locus_tag="CGSHiEE_00935"
/note="catalyzes the transformation of uracil to
pseudouracil at nucleotides U955, U2504, and U2580 in 23S
rRNA"
/codon_start=1
/transl_table=11
/product="23S rRNA pseudouridylate synthase C"
/protein_id="YP_001290060.1"
/db_xref="GI:148825307"
/db_xref="GeneID:5225312"
/translation="MTKQNEKIINSSVKMLTISEDESGQRIDNYLLAKLKGVPKSLIY
RIVRKGEVRVNKGRIKPEYKLQTGDVVRIPPVRVAEKNDAPISKNLNKVAALENQILF
EDDCLIILNKPSGIAVHGGSGLNFGVIEALRALRPEARFLELVHRLDRDTSGILLIAK
KRSALRNLHEQLRVKTVQKDYLALVRGQWQSHIKVIQAPLLKNELSSGERIVRVSEQG
KPSETRFSIEERYINATLVKASPVTGRTHQIRVHTQYAGHPIALDDKYGDKDFDKQMN
ELGLNRLFLHAFSIRFEHPKNGETLRFNASLDHQMKAILQKLRESK"
misc_feature 179500..180450
/locus_tag="CGSHiEE_00935"
/note="23S rRNA pseudouridylate synthase C; Provisional;
Region: PRK11025"
/db_xref="CDD:182909"
misc_feature 179557..179733
/locus_tag="CGSHiEE_00935"
/note="S4/Hsp/ tRNA synthetase RNA-binding domain; The
domain surface is populated by conserved, charged residues
that define a likely RNA-binding site; Found in stress
proteins, ribosomal proteins and tRNA synthetases; This
may imply a hitherto unrecognized...; Region: S4; cd00165"
/db_xref="CDD:29105"
misc_feature order(179560..179562,179596..179601,179605..179610,
179614..179619,179626..179631,179635..179637,
179656..179661,179662..179676,179680..179682)
/locus_tag="CGSHiEE_00935"
/note="RNA binding surface [nucleotide binding]; other
site"
/db_xref="CDD:29105"
misc_feature 179803..180360
/locus_tag="CGSHiEE_00935"
/note="Pseudouridine synthase, RsuA/RluD family; Region:
PseudoU_synth_RluCD_like; cd02869"
/db_xref="CDD:211346"
misc_feature order(179920..179931,180232..180234)
/locus_tag="CGSHiEE_00935"
/note="active site"
/db_xref="CDD:211346"
gene 180544..180819
/gene="hfq"
/locus_tag="CGSHiEE_00940"
/db_xref="GeneID:5225313"
CDS 180544..180819
/gene="hfq"
/locus_tag="CGSHiEE_00940"
/note="Stimulates the elongation of poly(A) tails"
/codon_start=1
/transl_table=11
/product="RNA-binding protein Hfq"
/protein_id="YP_001290061.1"
/db_xref="GI:148825308"
/db_xref="GeneID:5225313"
/translation="MAKGQSLQDPYLNALRRERIPVSIYLVNGIKLQGQIESFDQFVI
LLKNTVNQMVYKHAISTVVPARSVSHHNNNHHTTPTEAVENVETQAE"
misc_feature 180559..180735
/gene="hfq"
/locus_tag="CGSHiEE_00940"
/note="bacterial Hfq-like; Region: Hfq; cd01716"
/db_xref="CDD:212463"
misc_feature order(180559..180567,180574..180576,180619..180633,
180655..180663,180667..180672,180691..180735)
/gene="hfq"
/locus_tag="CGSHiEE_00940"
/note="hexamer interface [polypeptide binding]; other
site"
/db_xref="CDD:212463"
misc_feature order(180607..180627,180631..180684)
/gene="hfq"
/locus_tag="CGSHiEE_00940"
/note="Sm1 motif; other site"
/db_xref="CDD:212463"
misc_feature order(180616..180618,180628..180642,180679..180681,
180697..180699,180721..180726,180730..180732)
/gene="hfq"
/locus_tag="CGSHiEE_00940"
/note="RNA binding site [nucleotide binding]; other site"
/db_xref="CDD:212463"
misc_feature 180694..180729
/gene="hfq"
/locus_tag="CGSHiEE_00940"
/note="Sm2 motif; other site"
/db_xref="CDD:212463"
gene complement(180915..181871)
/locus_tag="CGSHiEE_00945"
/db_xref="GeneID:5225314"
CDS complement(180915..181871)
/locus_tag="CGSHiEE_00945"
/note="COG3283 Transcriptional regulator of aromatic amino
acids metabolism"
/codon_start=1
/transl_table=11
/product="transcriptional regulatory protein"
/protein_id="YP_001290062.1"
/db_xref="GI:148825309"
/db_xref="GeneID:5225314"
/translation="MTISKFNPQKPFECFIVQSEAMKSAVENAKRFAMFDAPLLIQGE
TGSGKDLLAKACHYQSLRRDKKFIAVNCAGLPDEDAESEMFGRKVGDSETIGFFEYAN
KGTVLLDGIAELSLSLQAKLLRFLTDGSFRRVGEEKEHYANVRVICTSQVPLHLLVEQ
GKVRADLFHRLNVLTINVPALRNRMADIEPLAQGFLQEISEELKISKPTFDKDFLLYL
QKYDWKGNVRELYNTLYRACSLVQDNHLTIESLNLAPPQSAVISLDEFGNKTLDEIIG
SYEAQVLKLFYAEYPSTRKLAQRLGVSHTAIANKLKQYGIGK"
misc_feature complement(180918..>181871)
/locus_tag="CGSHiEE_00945"
/note="Transcriptional regulator of aromatic amino acids
metabolism [Transcription / Amino acid transport and
metabolism]; Region: TyrR; COG3283"
/db_xref="CDD:33093"
misc_feature complement(181356..181763)
/locus_tag="CGSHiEE_00945"
/note="The AAA+ (ATPases Associated with a wide variety of
cellular Activities) superfamily represents an ancient
group of ATPases belonging to the ASCE (for additional
strand, catalytic E) division of the P-loop NTPase fold.
The ASCE division also includes ABC; Region: AAA; cd00009"
/db_xref="CDD:99707"
misc_feature complement(181722..181745)
/locus_tag="CGSHiEE_00945"
/note="Walker A motif; other site"
/db_xref="CDD:99707"
misc_feature complement(order(181419..181421,181545..181547,
181719..181742))
/locus_tag="CGSHiEE_00945"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:99707"
misc_feature complement(181542..181559)
/locus_tag="CGSHiEE_00945"
/note="Walker B motif; other site"
/db_xref="CDD:99707"
misc_feature complement(181362..181364)
/locus_tag="CGSHiEE_00945"
/note="arginine finger; other site"
/db_xref="CDD:99707"
gene complement(181986..183407)
/locus_tag="CGSHiEE_00950"
/db_xref="GeneID:5225315"
CDS complement(181986..183407)
/locus_tag="CGSHiEE_00950"
/note="COG0739 Membrane proteins related to
metalloendopeptidases"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290063.1"
/db_xref="GI:148825310"
/db_xref="GeneID:5225315"
/translation="MQHVKLARDRRKKRAYIKVGVFFVAILLILTGILLTIKDKSEEN
PIFSTSDSVEYHELNTSPNKNSTALQSDENATSYDDELQAKDDEVDEVKLSSDDLDAL
PQHAQDALNGLLDAADQAIRITDQFSYTVTEGDTLKDVLVLSGLDDSSVQPLIALDPE
LAHLKAGQQFYWILDKNDNLEYLNWLVSEKEERIYERLEDGKFKRQVIEKKSIWRKEV
LKGEIQNSLNSSLREKGLDTRQISQLSNALQWQVSLRKLKKGTQFAILVSREYLGDKL
TGQGNVEALRISSGGKNYYAVQAANGRYYNQQGETLGKGFARYPLQRQARVSSPFNPN
RRHPVTGRVRPHKGVDFSVSQGTPVIAPADGIVEKVAYQAGGAGRYVMLRHGREYQTV
YMHLSKSLVKAGQTVKKGERIALSGNTGISTGPHLHYEFHINGRAVNPLTVKLPGTSS
GMTSAERKQFLVRVREAEKMLKP"
misc_feature complement(182010..>183023)
/locus_tag="CGSHiEE_00950"
/note="putative peptidase; Provisional; Region: PRK11649"
/db_xref="CDD:183257"
misc_feature complement(182088..182378)
/locus_tag="CGSHiEE_00950"
/note="Peptidase family M23; Region: Peptidase_M23;
pfam01551"
/db_xref="CDD:201854"
gene 183585..184391
/locus_tag="CGSHiEE_00955"
/db_xref="GeneID:5225316"
CDS 183585..184391
/locus_tag="CGSHiEE_00955"
/note="COG1121 ABC-type Mn/Zn transport systems, ATPase
component"
/codon_start=1
/transl_table=11
/product="ABC transporter ATP-binding protein"
/protein_id="YP_001290064.1"
/db_xref="GI:148825311"
/db_xref="GeneID:5225316"
/translation="MNITAIRNEQNQQPLIQLKNINVVFAQKTALQGINLNIYPNSII
TIVGPNGGGKSTLLKTLLKLQTPTSGEVIYSKNVRIGYVPQKIHLDHSLPITVERFLS
LKKGLKTQEISTALEQLSISHLRKNNMQKLSGGEMQRVLLTRAILNKPNLLVLDEPTQ
GVDITGQAELYQLIHQTQQKLNCAVLMVSHDLHIVMADSKEVLCINQHICCAGTPDVL
SNDPTFMRLWGNQIAQNIGFYTHHHNHHHTLHGDVCSCNSSAVHCQNKDK"
misc_feature 183618..184301
/locus_tag="CGSHiEE_00955"
/note="ABC-type Mn/Zn transport systems, ATPase component
[Inorganic ion transport and metabolism]; Region: ZnuC;
COG1121"
/db_xref="CDD:31318"
misc_feature 183633..184223
/locus_tag="CGSHiEE_00955"
/note="P-loop containing Nucleoside Triphosphate
Hydrolases; Region: P-loop_NTPase; cl09099"
/db_xref="CDD:213113"
misc_feature 183726..183749
/locus_tag="CGSHiEE_00955"
/note="Walker A/P-loop; other site"
/db_xref="CDD:72971"
misc_feature order(183735..183740,183744..183752,183837..183839,
184050..184055,184152..184154)
/locus_tag="CGSHiEE_00955"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:72971"
misc_feature 183828..183839
/locus_tag="CGSHiEE_00955"
/note="Q-loop/lid; other site"
/db_xref="CDD:72971"
misc_feature 183978..184007
/locus_tag="CGSHiEE_00955"
/note="ABC transporter signature motif; other site"
/db_xref="CDD:72971"
misc_feature 184038..184055
/locus_tag="CGSHiEE_00955"
/note="Walker B; other site"
/db_xref="CDD:72971"
misc_feature 184062..184073
/locus_tag="CGSHiEE_00955"
/note="D-loop; other site"
/db_xref="CDD:72971"
misc_feature 184140..184160
/locus_tag="CGSHiEE_00955"
/note="H-loop/switch region; other site"
/db_xref="CDD:72971"
gene 184391..185176
/locus_tag="CGSHiEE_00960"
/db_xref="GeneID:5225317"
CDS 184391..185176
/locus_tag="CGSHiEE_00960"
/note="COG1108 ABC-type Mn2+/Zn2+ transport systems,
permease components"
/codon_start=1
/transl_table=11
/product="23S rRNA pseudouridylate synthase C"
/protein_id="YP_001290065.1"
/db_xref="GI:148825312"
/db_xref="GeneID:5225317"
/translation="MFEILFPALLTGIVLSLITAPLGVFVVWRKMAYFGDTLSHSALL
GVALGIFLQVNPYIAIVVLTLILAIAMVWLESNTQFSIDTLLGIIAHSCLSLGVVTVG
LLRNVRVDLMNYLFGDLLAINYTDLIYIGIGVIIVLSTLIYFWQSLLSTTVSPELAQV
EGINIKKMRFILMILTALTIALSMKFVGALIITSLLIIPAATARRFARTPESMVGWAI
VVSMLSIIAGLILSAFYDTAAGPSVVICSAFLFVLSLFKKERL"
misc_feature 184403..185155
/locus_tag="CGSHiEE_00960"
/note="Transmembrane subunit (TM), of Periplasmic Binding
Protein (PBP)-dependent ATP-Binding Cassette (ABC)
transporters involved in the uptake of siderophores, heme,
vitamin B12, or the divalent cations Mg2+ and Zn2+.
PBP-dependent ABC transporters consist of...; Region:
TM_ABC_iron-siderophores_like; cd06550"
/db_xref="CDD:119348"
misc_feature order(184457..184459,184469..184477,184814..184819,
184823..184831,184835..184840,184844..184861,
184865..184873,184997..184999,185018..185020)
/locus_tag="CGSHiEE_00960"
/note="ABC-ATPase subunit interface; other site"
/db_xref="CDD:119348"
misc_feature order(184472..184474,184478..184480,184493..184495,
184640..184645,184652..184657,184664..184669,
184676..184678,184685..184690,184694..184696,
184724..184729,184736..184738,184964..184966,
185111..185113,185120..185125,185132..185134,
185141..185146,185153..185155)
/locus_tag="CGSHiEE_00960"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:119348"
misc_feature order(184694..184696,184766..184768,184940..184942,
184952..184954,185087..185089,185102..185104)
/locus_tag="CGSHiEE_00960"
/note="putative PBP binding regions; other site"
/db_xref="CDD:119348"
gene 185265..186212
/locus_tag="CGSHiEE_00965"
/db_xref="GeneID:5225307"
CDS 185265..186212
/locus_tag="CGSHiEE_00965"
/EC_number="6.4.1.2"
/note="catalyzes the carboxylation of acetyl-CoA to
malonyl-CoA; forms a tetramer composed of two alpha (AccA)
and two beta (AccD) subunits; one of the two catalytic
subunits that can form the acetyl CoA carboxylase enzyme
together with a carrier protein"
/codon_start=1
/transl_table=11
/product="acetyl-CoA carboxylase carboxyltransferase
subunit alpha"
/protein_id="YP_001290066.1"
/db_xref="GI:148825313"
/db_xref="GeneID:5225307"
/translation="MNQEYLDFELPIAELEAKIEALRAASDDKVDLTDEIKRLQKKSN
ELTKKTFANLDAWQVSRMARHPNRPYTLDYIEYIFTEFEELAGDRAFADDKAIVGGLA
RLDGRPVMVIGHQKGRTVKDKVSRNFGMPAPEGYRKALRLMEMAERFKLPIITFIDTP
GAYPGIGAEERGQAEAIARNLREMAQLTVPVICTVIGEGGSGGALAIGVGDKVNMLQY
STYSVISPEGCASILWKSAEKASTAAEVMGLTASRLKELNLIDNIVQEPLGGAHRNYA
KIAENLKLRLKEDLAELDGLSKEELLNRRYERLMSYGYC"
misc_feature 185265..186209
/locus_tag="CGSHiEE_00965"
/note="acetyl-CoA carboxylase carboxyltransferase subunit
alpha; Validated; Region: PRK05724"
/db_xref="CDD:180223"
misc_feature 185280..186206
/locus_tag="CGSHiEE_00965"
/note="acetyl-CoA carboxylase carboxyltransferase alpha
subunit; Provisional; Region: accA; CHL00198"
/db_xref="CDD:164574"
gene 186285..187151
/locus_tag="CGSHiEE_00970"
/db_xref="GeneID:5225308"
CDS 186285..187151
/locus_tag="CGSHiEE_00970"
/EC_number="2.7.1.35"
/note="catalyzes the formation of pyridoxal 5'-phosphate
from pyridoxal"
/codon_start=1
/transl_table=11
/product="pyridoxamine kinase"
/protein_id="YP_001290067.1"
/db_xref="GI:148825314"
/db_xref="GeneID:5225308"
/translation="MKNVLSIQSHVVYGFAGNKSATFPMQLLGVDVWALNTVQFSNHT
QYGKWTGMVIPQEQIREIVTGLDNIEKLQECDALLSGYLGSAEQVDQILFALEQIKLR
NPNALYLCDPVMPHPKKSCVVANGVCEALIEKAIPVADIMTPNLHELRQLTEFPINTF
DDVLKAVNALIAKGVKKVLVKHLGSAGKINDPDTFEIIMATPEGVWHLSRPLYQFNFE
PVGVGDLIAGTFLANLLNGKSDVEAFEAMNNEVAGVMKTTFELGSYELQTIAARFEIL
NPSSNYKAEKVA"
misc_feature 186285..187148
/locus_tag="CGSHiEE_00970"
/note="pyridoxamine kinase; Validated; Region: PRK05756"
/db_xref="CDD:180238"
misc_feature 186291..187064
/locus_tag="CGSHiEE_00970"
/note="Pyridoxal kinase plays a key role in the synthesis
of the active coenzyme pyridoxal-5'-phosphate (PLP), by
catalyzing the phosphorylation of the precursor vitamin B6
in the presence of Zn2+ and ATP. Mammals are unable to
synthesize PLP de novo and...; Region:
pyridoxal_pyridoxamine_kinase; cd01173"
/db_xref="CDD:29357"
misc_feature order(186291..186293,186312..186314,186318..186323,
186327..186329,186339..186341,186351..186353,
186360..186362,186375..186392,186399..186401,
186408..186410,186435..186440,186444..186446,
186465..186470,186489..186491)
/locus_tag="CGSHiEE_00970"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:29357"
misc_feature order(186309..186311,186330..186335,186402..186404,
186411..186416,186429..186431,186528..186530,
186534..186536,186942..186947,186954..186956)
/locus_tag="CGSHiEE_00970"
/note="pyridoxal binding site [chemical binding]; other
site"
/db_xref="CDD:29357"
misc_feature order(186615..186617,186630..186632,186711..186713,
186717..186719,186726..186728,186825..186830,
186867..186869,186912..186914,186918..186923,
186939..186941,186948..186956,186960..186962,
187035..187037,187047..187049)
/locus_tag="CGSHiEE_00970"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:29357"
gene 187151..188443
/locus_tag="CGSHiEE_00975"
/db_xref="GeneID:5225309"
CDS 187151..188443
/locus_tag="CGSHiEE_00975"
/EC_number="2.7.1.35"
/note="COG0037 Predicted ATPase of the PP-loop superfamily
implicated in cell cycle control"
/codon_start=1
/transl_table=11
/product="pyridoxine kinase"
/protein_id="YP_001290068.1"
/db_xref="GI:148825315"
/db_xref="GeneID:5225309"
/translation="MDLLSDIEKQLQKATAQGFLIALSGGLDSTVLLSLFAKLRQKQP
HLPPLSVRAIHIHHGLSPNADSWAKHCQDLCDQFQIPLIIERVQVDKTNGIEAGAREA
RYQAIKKHLQTQEILVTAHHLNDQTETFFLALKRGSGLQGLGAMQQQSVLFGMPILRP
LLGFTRTQLENYAQKEKLNWITDESNGDNRFDRNFLRNEILPKLRERWAYFDLAVQRS
AQHCFEQQQLINDLLSEAFAEHCQIKNQFKLCQFRKYSLAKQTALLRMWLAENQLEMP
SKRQLTQLINDVVFAKEEANPQFQLVNKVIRRYQDRLYLTKPFSDLTKYCLKLEQNTL
SLPDDLGNLSVQENEHNLIFHWQDFSVTLEKTNLPISIRFGYSGKVKHHLKRPREDIK
KIWQELSVPPWERNRIPLIFYGNKLKSAVGFFRVFDEY"
misc_feature 187154..188422
/locus_tag="CGSHiEE_00975"
/note="tRNA(Ile)-lysidine synthetase; Provisional; Region:
tilS; PRK10660"
/db_xref="CDD:182626"
misc_feature 187205..187756
/locus_tag="CGSHiEE_00975"
/note="N-terminal domain of predicted ATPase of the
PP-loop faimly implicated in cell cycle control [Cell
division and chromosome partitioning]. This is a subfamily
of Adenine nucleotide alpha hydrolases
superfamily.Adeninosine nucleotide alpha hydrolases...;
Region: PP-ATPase; cd01992"
/db_xref="CDD:30179"
misc_feature order(187214..187222,187226..187237,187313..187315,
187319..187321)
/locus_tag="CGSHiEE_00975"
/note="Ligand Binding Site [chemical binding]; other site"
/db_xref="CDD:30179"
misc_feature 187889..188095
/locus_tag="CGSHiEE_00975"
/note="TilS substrate binding domain; Region: TilS;
pfam09179"
/db_xref="CDD:204159"
misc_feature 188258..>188422
/locus_tag="CGSHiEE_00975"
/note="TilS substrate C-terminal domain; Region: TilS_C;
pfam11734"
/db_xref="CDD:204723"
gene complement(188451..189122)
/locus_tag="CGSHiEE_00980"
/db_xref="GeneID:5225310"
CDS complement(188451..189122)
/locus_tag="CGSHiEE_00980"
/note="MutH; Sequence-specific endonuclease that cleaves
unmethylated GATC sequences during DNA repair"
/codon_start=1
/transl_table=11
/product="DNA mismatch repair protein"
/protein_id="YP_001290069.1"
/db_xref="GI:148825316"
/db_xref="GeneID:5225310"
/translation="MIPQTLEQLLSQAQSIAGLTFGELADELHIPVPPDLKRDKGWVG
MLLERALGATAGSKAEQDFSHLGVELKTLPINAEGYPLETTFVSLAPLVQNSGVKWEN
SHVRHKLSCVLWMPIEGSRHIPLRERHIGAPIFWKPTAEQERQLKQDWEELMDLIVLG
KLDQITARIGEVMQLRPKGANSKAITKGIGKNGEVIDTLPLGFYLRKEFTAQILNAFL
ETKPL"
misc_feature complement(188469..189098)
/locus_tag="CGSHiEE_00980"
/note="MutH is a 28kD endonuclease involved in
methyl-directed DNA mismatch repair in gram negative
bacteria. MutH is both sequence-specific and
methylation-specific, introducing a nick in the
unmethylated strand of a hemi-methylated d(GATC) DNA
duplex. MutH...; Region: MutH_Sau3AI; cd00583"
/db_xref="CDD:29958"
misc_feature complement(order(188589..188591,188790..188792,
188799..188804,188811..188813,188856..188858,
188865..188867,188874..188876,188910..188912,
189003..189005))
/locus_tag="CGSHiEE_00980"
/note="putative DNA-binding cleft [nucleotide binding];
other site"
/db_xref="CDD:29958"
misc_feature complement(order(188799..188801,188910..188912,
188916..188918,188937..188939,188979..188981))
/locus_tag="CGSHiEE_00980"
/note="putative DNA clevage site; other site"
/db_xref="CDD:29958"
misc_feature complement(188469..188501)
/locus_tag="CGSHiEE_00980"
/note="molecular lever; other site"
/db_xref="CDD:29958"
gene complement(189119..189658)
/locus_tag="CGSHiEE_00985"
/db_xref="GeneID:5225311"
CDS complement(189119..189658)
/locus_tag="CGSHiEE_00985"
/note="COG0350 Methylated DNA-protein cysteine
methyltransferase"
/codon_start=1
/transl_table=11
/product="methylated-DNA-protein-cysteine
methyltransferase"
/protein_id="YP_001290070.1"
/db_xref="GI:148825317"
/db_xref="GeneID:5225311"
/translation="MTALYYTYYPSPVGRLLILSDGESITHIDFEKEQYAPNPKWHKQ
DELPVFQKVRLAFKRYFNGEVERFLDIPLKPEGTAFQQAIWQALREIDYGELSSYGEL
ALRINNPKAVRAVGGAVGSNPISIIIPCHRILGKDRTLTGFGGGLEAKRFLLQLEKIP
YIDKGTENTKPRFFKKYHE"
misc_feature complement(189434..189652)
/locus_tag="CGSHiEE_00985"
/note="6-O-methylguanine DNA methyltransferase,
ribonuclease-like domain; Region: Methyltransf_1N;
pfam02870"
/db_xref="CDD:145821"
misc_feature complement(189185..189646)
/locus_tag="CGSHiEE_00985"
/note="methylated-DNA--protein-cysteine methyltransferase;
Provisional; Region: PRK00901"
/db_xref="CDD:179160"
misc_feature complement(189185..189421)
/locus_tag="CGSHiEE_00985"
/note="The DNA repair protein O6-alkylguanine-DNA
alkyltransferase (ATase; also known as AGT, AGAT and MGMT)
reverses O6-alkylation DNA damage by transferring O6-alkyl
adducts to an active site cysteine irreversibly, without
inducing DNA strand breaks. ATases...; Region: ATase;
cd06445"
/db_xref="CDD:119438"
misc_feature complement(order(189233..189235,189254..189256,
189269..189271,189293..189295,189299..189304,
189311..189313,189317..189322,189326..189328,
189335..189337,189359..189364,189416..189421))
/locus_tag="CGSHiEE_00985"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:119438"
misc_feature complement(order(189188..189190,189260..189262,
189266..189271,189362..189364))
/locus_tag="CGSHiEE_00985"
/note="active site"
/db_xref="CDD:119438"
gene complement(189734..191104)
/locus_tag="CGSHiEE_00990"
/db_xref="GeneID:5225222"
CDS complement(189734..191104)
/locus_tag="CGSHiEE_00990"
/note="COG2067 Long-chain fatty acid transport protein"
/codon_start=1
/transl_table=11
/product="long-chain fatty acid transport protein"
/protein_id="YP_001290071.1"
/db_xref="GI:148825318"
/db_xref="GeneID:5225222"
/translation="MKKFNQSLLATAMLLAAGGANAAAFQLAEVSTSGLGRAYAGEAA
IADNASVVATNPALMSLFKTNQFSVGGVYVDSRINMNGDVDSYAIISDSIKVTNDGSA
SARNVVPGAFVPNLYFVAPVNDKFALGAGMNVNFGLKSEYDDSYDAGVFGGKTDLTAI
NLNLSGAYRVTEGLSLGLGVNAVYAKAQVERNAGLIADTVKDNQVKNTLTVQQEPLKF
IDKYLPSKDTSVVSLQDRAAWGFGWNAGVMYQFNEANRIGLAYHSKVDIDFTDRTATS
LEANVIKASKTGDLTLTLPDYLELSGFHQLTDKLAVHYSYKYTHWSRLTKLNASFEDG
KKAFDKELQYSNNSRVALGASYNLDEKLTLRAGIAYDQAASRHQRSAAIPDTDRTWYS
LGATYKFTPNLSVDLGYAYLKGKKVHFKEVKTIGDKRSLALSTTANYTSQAHANLYGL
NLNYSF"
misc_feature complement(189737..191020)
/locus_tag="CGSHiEE_00990"
/note="Outer membrane protein transport protein
(OMPP1/FadL/TodX); Region: Toluene_X; pfam03349"
/db_xref="CDD:202603"
gene 191310..191597
/locus_tag="CGSHiEE_00995"
/db_xref="GeneID:5225223"
CDS 191310..191597
/locus_tag="CGSHiEE_00995"
/note="COG3691 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290072.1"
/db_xref="GI:148825319"
/db_xref="GeneID:5225223"
/translation="MTVKCKAEESLTCSCVDVGTIIDGSDCSVEVHQFYSTEADANAA
LERLTKKARNTESDPCEIKSEIVAVENGVQLNASFTFSCQAEAMIFELANR"
misc_feature 191310..191594
/locus_tag="CGSHiEE_00995"
/note="conserved hypothetical protein; Region: TIGR00743"
/db_xref="CDD:129826"
gene complement(191695..192519)
/locus_tag="CGSHiEE_01000"
/db_xref="GeneID:5225224"
CDS complement(191695..192519)
/locus_tag="CGSHiEE_01000"
/note="COG1409 Predicted phosphohydrolases"
/codon_start=1
/transl_table=11
/product="cyclic 3',5'-adenosine monophosphate
phosphodiesterase"
/protein_id="YP_001290073.1"
/db_xref="GI:148825320"
/db_xref="GeneID:5225224"
/translation="MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQV
LKEIQQENKEFDVILATGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAE
FLNQPPMNVAKHLLLGEHWQALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLV
VLHHHLLPTNSAWLDQHNLRNSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMA
TPATCIQFKPDCQYFSLDTLQPGWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY"
misc_feature complement(191764..192477)
/locus_tag="CGSHiEE_01000"
/note="Enterobacter aerogenes GpdQ and related proteins,
metallophosphatase domain; Region: MPP_GpdQ; cd07402"
/db_xref="CDD:163645"
misc_feature complement(191905..192477)
/locus_tag="CGSHiEE_01000"
/note="Calcineurin-like phosphoesterase; Region:
Metallophos; pfam00149"
/db_xref="CDD:201036"
misc_feature complement(order(191848..191850,191908..191910,
191914..191916,192031..192033,192238..192243,
192322..192324,192331..192333,192451..192453,
192457..192459))
/locus_tag="CGSHiEE_01000"
/note="active site"
/db_xref="CDD:163645"
misc_feature complement(order(191908..191910,191914..191916,
192031..192033,192241..192243,192331..192333,
192451..192453,192457..192459))
/locus_tag="CGSHiEE_01000"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:163645"
misc_feature complement(order(191767..191769,191773..191775,
191782..191784,191869..191871,191875..191883,
191890..191904,191923..191925,191929..191931,
192010..192015,192019..192021,192286..192288,
192313..192315,192322..192324,192379..192384,
192391..192396,192403..192405,192412..192414))
/locus_tag="CGSHiEE_01000"
/note="hexamer interface [polypeptide binding]; other
site"
/db_xref="CDD:163645"
gene complement(192529..193161)
/locus_tag="CGSHiEE_01005"
/db_xref="GeneID:5225225"
CDS complement(192529..193161)
/locus_tag="CGSHiEE_01005"
/note="COG0494 NTP pyrophosphohydrolases including
oxidative damage repair enzymes"
/codon_start=1
/transl_table=11
/product="cyclic 3',5'-adenosine monophosphate
phosphodiesterase"
/protein_id="YP_001290074.1"
/db_xref="GI:148825321"
/db_xref="GeneID:5225225"
/translation="MSEIQHFSQQDIEILGEQTLYEGFFTLKRIQFKHKLFAGGQSGV
VTRELLIKGAASAVIAYDPKEDSVILVEQVRIGAAYHPESHRSPWLLELIAGMVEKGE
KPEDVALRESEEEAGIQVKNLTHCLSVWDSPGGIVERIHLFAGEVDSAQAKGIHGLAE
ENEDIKVHVVKREQAYQWMCEGKIDNGIAVIGLQWLQLNYAQLQQSWKRS"
misc_feature complement(192568..193134)
/locus_tag="CGSHiEE_01005"
/note="nudix-type nucleoside diphosphatase, YffH/AdpP
family; Region: TIGR00052"
/db_xref="CDD:129162"
misc_feature complement(192565..193008)
/locus_tag="CGSHiEE_01005"
/note="ADP-ribose pyrophosphatase (ADPRase) catalyzes the
hydrolysis of ADP-ribose and a variety of additional
ADP-sugar conjugates to AMP and ribose-5-phosphate. Like
other members of the Nudix hydrolase superfamily, it
requires a divalent cation, such as Mg2+; Region:
ADPRase_NUDT5; cd03424"
/db_xref="CDD:72882"
misc_feature complement(order(192565..192570,192580..192582,
192589..192591,192601..192603,192622..192627,
192664..192666,192670..192675,192745..192759,
192763..192765,192769..192780,192895..192897,
192934..192936,192940..192942,192946..192948,
193000..193002,193006..193008))
/locus_tag="CGSHiEE_01005"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:72882"
misc_feature complement(order(192748..192750,192817..192819,
192829..192831,192871..192873,192937..192939,
192997..192999))
/locus_tag="CGSHiEE_01005"
/note="ADP-ribose binding site [chemical binding]; other
site"
/db_xref="CDD:72882"
misc_feature complement(order(192673..192675,192748..192750,
192817..192819,192829..192831,192871..192879,
192937..192939))
/locus_tag="CGSHiEE_01005"
/note="active site"
/db_xref="CDD:72882"
misc_feature complement(order(192808..192861,192865..192876))
/locus_tag="CGSHiEE_01005"
/note="nudix motif; other site"
/db_xref="CDD:72882"
misc_feature complement(order(192673..192675,192817..192819,
192829..192831))
/locus_tag="CGSHiEE_01005"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:72882"
gene complement(193360..194688)
/gene="xseA"
/locus_tag="CGSHiEE_01010"
/db_xref="GeneID:5225226"
CDS complement(193360..194688)
/gene="xseA"
/locus_tag="CGSHiEE_01010"
/EC_number="3.1.11.6"
/note="bidirectionally degrades single-stranded DNA into
large acid-insoluble oligonucleotides"
/codon_start=1
/transl_table=11
/product="exodeoxyribonuclease VII large subunit"
/protein_id="YP_001290075.1"
/db_xref="GI:148825322"
/db_xref="GeneID:5225226"
/translation="MNNMSDNIYSVSQLNSAARQMLEGHFSQIWLTGEISNFTQPVSG
HWYLTLKDENAQVRCAMFRMKNLRVAFRPQNGMQVLVRANVSLYEPRGDYQLIIDSMH
PAGEGLLQQQFEALKMKLAAEGLFAQNLKKNLPHFSKAVGIITSSTGAALQDILHILA
RRDPSLKVVIYPTAVQGKEATAEIVQMIELANARQEVDVLIVGRGGGSLEDLWCFNEE
EVARAIFRSTLPIISAVGHETDVTIADFVADLRAPTPSAAAELVSRNQDELLQQLRHQ
QQRLDMAFDRLFTRKSQRLKQLALRLHNQHPQNQLRVQQAKNEQLTHRLQLAMLRQFE
NTQQKFTALSVRLKQNPLPYRVQRHQQRLEQLQVRLNFCVNRQVTERQNKLATLCGKL
DGLSPLKVLARGYSIAENPQGKAIVSVKDVNQGDFITTQVADGKIVSKVL"
misc_feature complement(193366..194661)
/gene="xseA"
/locus_tag="CGSHiEE_01010"
/note="exodeoxyribonuclease VII, large subunit; Region:
xseA; TIGR00237"
/db_xref="CDD:161783"
misc_feature complement(194374..194607)
/gene="xseA"
/locus_tag="CGSHiEE_01010"
/note="ExoVII_LU_OBF: A subfamily of OB folds
corresponding to the N-terminal OB-fold domain of
Escherichia coli exodeoxyribonuclease VII (ExoVII) large
subunit. E. coli ExoVII is composed of two non-identical
subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF;
cd04489"
/db_xref="CDD:72961"
misc_feature complement(order(194383..194385,194443..194445,
194449..194451,194455..194457,194599..194601))
/gene="xseA"
/locus_tag="CGSHiEE_01010"
/note="generic binding surface II; other site"
/db_xref="CDD:72961"
misc_feature complement(order(194398..194406,194431..194439,
194458..194460,194503..194505,194509..194517,
194533..194535,194539..194550,194578..194586))
/gene="xseA"
/locus_tag="CGSHiEE_01010"
/note="generic binding surface I; other site"
/db_xref="CDD:72961"
gene complement(194681..195895)
/gene="xseA"
/locus_tag="CGSHiEE_01015"
/db_xref="GeneID:5225227"
CDS complement(194681..195895)
/gene="xseA"
/locus_tag="CGSHiEE_01015"
/EC_number="3.1.11.6"
/note="COG2850 Uncharacterized conserved protein"
/codon_start=1
/transl_table=11
/product="exodeoxyribonuclease VII large subunit"
/protein_id="YP_001290076.1"
/db_xref="GI:148825323"
/db_xref="GeneID:5225227"
/translation="MTALSSVDFCLPEHITPEIFLRDYWQKKPLVIRNGLPEIVGQFE
PQDIIELAQNEDVTARLVKTFSNDDWKVFFSPLSEKDFQKLPEKWSVLVQNLEQWSPE
LGQLWNKFGFIPQWQRDDIMVSYAPKGGSVGKHYDEYDVFLVQGYGHRRWQVGKWCDA
STEFKPNQSIRIFDDMGELVIDEVMNPGDILYIPARMAHYGVAEDDCLTFSFGLRYPN
LSNLIDSVSKGFCHQDPDLNLSEFDLPLRLSQSVQATGKLADENIQAMKQLLLDKLAN
SKAFDTLFKQAVASAVSSRRYELLVSDEMCDPDEVRSILEEDDAFLSQDNNCKLLYTE
NPLRIYANGEWLDELNVIETEVLKRLSDGESLDWAFLSSLVNKTEDPETSMDLLLDSI
CNWVDDGWVLIE"
misc_feature complement(194684..195895)
/gene="xseA"
/locus_tag="CGSHiEE_01015"
/note="Uncharacterized conserved protein [Function
unknown]; Region: COG2850"
/db_xref="CDD:32678"
gene complement(195898..196206)
/locus_tag="CGSHiEE_01020"
/db_xref="GeneID:5225214"
CDS complement(195898..196206)
/locus_tag="CGSHiEE_01020"
/note="COG2914 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290077.1"
/db_xref="GI:148825324"
/db_xref="GeneID:5225214"
/translation="MNQINIEIAYAFPERYYLKSFQVDEGITVQTAITQSGILSQFPE
IDLSTNKIGIFSRPIKLTDVLKEGDRIEIYRPLLADPKEIRRKRAAEQAAAKNKEKGA
"
misc_feature complement(195964..196206)
/locus_tag="CGSHiEE_01020"
/note="hypothetical protein; Validated; Region: PRK01777"
/db_xref="CDD:179336"
gene 196483..196974
/locus_tag="CGSHiEE_01025"
/db_xref="GeneID:5225215"
CDS 196483..196974
/locus_tag="CGSHiEE_01025"
/EC_number="3.1.1.29"
/note="COG0193 Peptidyl-tRNA hydrolase"
/codon_start=1
/transl_table=11
/product="peptidyl-tRNA hydrolase"
/protein_id="YP_001290078.1"
/db_xref="GI:148825325"
/db_xref="GeneID:5225215"
/translation="MARRFNVSLNPESKFFGKTARTLVNGKEVRLLVPTTFMNLSGKA
VGALASFYRIKPEEILVIHDELDLPAGTAKLKQGGGHGGHNGLKDIVAQLGNNNNFYR
LRIGIGHPGHRDLVAGYVLNKPSPADRDALEKVLDEATDCVEIIFKDGMIKATNRLNS
FKI"
misc_feature 196483..196920
/locus_tag="CGSHiEE_01025"
/note="Peptidyl-tRNA hydrolase (PTH) is a monomeric
protein that cleaves the ester bond linking the nascent
peptide and tRNA when peptidyl-tRNA is released
prematurely from the ribosome. This ensures the recycling
of peptidyl-tRNAs into tRNAs produced through...; Region:
PTH; cd00462"
/db_xref="CDD:73208"
misc_feature order(196591..196596,196672..196674,196732..196734)
/locus_tag="CGSHiEE_01025"
/note="putative active site [active]"
/db_xref="CDD:73208"
gene 197022..198113
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/db_xref="GeneID:5225216"
CDS 197022..198113
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/note="translation-associated GTPase; the crystal
structure of the Haemophilus influenzae YchF protein
showed similarity to the yeast structure (PDB: 1NI3);
fluorescence spectroscopy revealed nucleic acid binding;
the yeast protein YBR025c interacts with the translation
elongation factor eEF1"
/codon_start=1
/transl_table=11
/product="GTP-dependent nucleic acid-binding protein EngD"
/protein_id="YP_001290079.1"
/db_xref="GI:148825326"
/db_xref="GeneID:5225216"
/translation="MGFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNTGVV
PMPDPRLDALAEIVKPERILPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGH
VVRCFENDDIVHVAGKIDPLDDIETINTELALADLDSCERAIQRLQKRAKGGDKEAKF
ELSVMEKILPVLENAGMIRSVGLDKEELQAIKSYNFLTLKPTMYIANVNEDGFENNPY
LDCVREIAEKEGAVVVPVCAAIESEIAELDDEEKVEFLQDLGIEEPGLNRVIRAGYAL
LNLQTYFTAGVKEVRAWTVSVGATAPKAAAVIHTDFEKGFIRAEVIAYEDFIQFNGEN
GAKEAGKWRLEGKDYIVQDGDVMHFRFNV"
misc_feature 197022..198110
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/note="GTP-binding protein YchF; Reviewed; Region:
PRK09601"
/db_xref="CDD:181981"
misc_feature 197034..197852
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/note="YchF GTPase; Region: YchF; cd01900"
/db_xref="CDD:206687"
misc_feature 197046..197069
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/note="G1 box; other site"
/db_xref="CDD:206687"
misc_feature order(197055..197057,197061..197072,197640..197645,
197649..197651,197730..197738)
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/note="GTP/Mg2+ binding site [chemical binding]; other
site"
/db_xref="CDD:206687"
misc_feature 197115..197138
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/note="Switch I region; other site"
/db_xref="CDD:206687"
misc_feature 197127..197129
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/note="G2 box; other site"
/db_xref="CDD:206687"
misc_feature order(197232..197261,197280..197309)
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/note="Switch II region; other site"
/db_xref="CDD:206687"
misc_feature 197235..197246
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/note="G3 box; other site"
/db_xref="CDD:206687"
misc_feature 197640..197651
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/note="G4 box; other site"
/db_xref="CDD:206687"
misc_feature 197730..197738
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/note="G5 box; other site"
/db_xref="CDD:206687"
misc_feature 197856..198104
/locus_tag="CGSHiEE_01030"
/gene_synonym="ychF"
/note="TGS_YchF_C: This subfamily represents TGS
domain-containing YchF GTP-binding protein, a universally
conserved GTPase whose function is unknown. The N-terminal
domain of the YchF protein belongs to the Obg-like family
of GTPases, and some members of the...; Region:
TGS_YchF_C; cd04867"
/db_xref="CDD:133440"
misc_feature 198187..200051
/note="potential frameshift: common BLAST hit:
gi|59802031|ref|YP_208743.1| putative trans-acylase
protein [Neisseria gonorrhoeae FA 1090]"
gene complement(200093..201235)
/locus_tag="CGSHiEE_01045"
/db_xref="GeneID:5225217"
CDS complement(200093..201235)
/locus_tag="CGSHiEE_01045"
/note="COG0349 Ribonuclease D"
/codon_start=1
/transl_table=11
/product="ribonuclease D"
/protein_id="YP_001290080.1"
/db_xref="GI:148825327"
/db_xref="GeneID:5225217"
/translation="MIKECQNPPHFRVIADNATLLEVCNLAQQKSAVALDTEFMRVST
YFPKLGLIQLYDGERVSLIDPLAITDFSPFIALLANPKVLKILHSCSEDLLVFLQEFD
QLPRPMIDTQIMARFIGLGASAGLAKLAQQYLNIEIDKGATRTNWIKRPLSDIQLQYA
AGDVWYLLPLYHILEKELAKTPWEKAVSDDCELALSKTHKLQERDSEKAYLDIPNAWK
LNPLELSRLRILAKWRQNVAIERDLALSYIVKSDNLWKVAKNNPRNISEMLEMGLTEN
EVRVRGKKILQLLAQARRISSNDYPKPIERISEDPRYKKTIRLLQEKVNSLTPAGLSP
EIVASKRTLDELIKWVWKYDCSQDKLPELLIGWRKPIGEKLVDVLK"
misc_feature complement(200096..201205)
/locus_tag="CGSHiEE_01045"
/note="ribonuclease D; Provisional; Region: PRK10829"
/db_xref="CDD:182762"
misc_feature complement(200648..201178)
/locus_tag="CGSHiEE_01045"
/note="DEDDy 3'-5' exonuclease domain of Ribonuclease D
and similar proteins; Region: RNaseD_exo; cd06142"
/db_xref="CDD:176654"
misc_feature complement(order(200747..200749,200759..200761,
200858..200863,200957..200965,200969..200974,
201119..201130))
/locus_tag="CGSHiEE_01045"
/note="putative active site [active]"
/db_xref="CDD:176654"
misc_feature complement(order(200747..200749,200759..200761,
200957..200959,201122..201124,201128..201130))
/locus_tag="CGSHiEE_01045"
/note="catalytic site [active]"
/db_xref="CDD:176654"
misc_feature complement(order(200747..200749,200759..200761,
200858..200863,200960..200965,200969..200974,
201119..201127))
/locus_tag="CGSHiEE_01045"
/note="putative substrate binding site [chemical binding];
other site"
/db_xref="CDD:176654"
misc_feature complement(200336..200578)
/locus_tag="CGSHiEE_01045"
/note="Helicase and RNase D C-terminal; Region: HRDC;
smart00341"
/db_xref="CDD:128635"
gene complement(201291..202979)
/locus_tag="CGSHiEE_01050"
/db_xref="GeneID:5225194"
CDS complement(201291..202979)
/locus_tag="CGSHiEE_01050"
/EC_number="6.2.1.3"
/note="Activates fatty acids by binding to coenzyme A"
/codon_start=1
/transl_table=11
/product="long-chain-fatty-acid--CoA ligase"
/protein_id="YP_001290081.1"
/db_xref="GI:148825328"
/db_xref="GeneID:5225194"
/translation="MEKIWFQNYPEGSEKFLDTSKYESILDMFDKAVREHPDRPAYIN
MGQVLTFRKLEERSRAFAAYLQNEFKLQRGDRVALMMPNLLQYPIALFGILRAGLIAV
NVNPLYTPRELEHQLQDSGAVAIVVVSNFASTLEKVVFNTNVKHVILTRMGDQLSFGK
RTLINFVVKYVKKLVPKYKLPHAVTFREVLSIGKYRQYVRPEMSREDLAFLQYTGGTT
GMAKGAMLTHGNIITNVFQAKWIAEPFIGDHSRTRSAILALPLYHVFALTVNCLLFLE
LGVTAILITNPRDIEGFVKELKKYRFEAITGVNTLFNALLNNENFKEVDFSALKLSVG
GGMAIQQSVATRWHELTGCNIIEGYGMTECSPLIAACPINVVKHNGTIGVPVPNTDIK
IIKDDGSDAKIGEAGELWVKGEQVMRGYWQRPEATSEVLKDGWMATGDIIIMDESYSL
RIVDRKKDMILVSGFNVYPNEIEDVVMLNYKVAEAVAIGVPHAVSGETIKIFVVKKDD
TLTRDELRNHCRQYLTGYKIPKEIEFRDELPKTNVGKILRRVLRDEEIAKRSKH"
misc_feature complement(201294..202979)
/locus_tag="CGSHiEE_01050"
/note="long-chain-fatty-acid--CoA ligase; Validated;
Region: PRK08974"
/db_xref="CDD:181600"
misc_feature complement(201519..202832)
/locus_tag="CGSHiEE_01050"
/note="AMP-binding enzyme; Region: AMP-binding; pfam00501"
/db_xref="CDD:201270"
misc_feature complement(<201315..201404)
/locus_tag="CGSHiEE_01050"
/note="Domain of unknown function (DUF4009); Region:
DUF4009; pfam13193"
/db_xref="CDD:205374"
gene complement(203022..203573)
/locus_tag="CGSHiEE_01055"
/db_xref="GeneID:5225195"
CDS complement(203022..203573)
/locus_tag="CGSHiEE_01055"
/note="COG3065 Starvation-inducible outer membrane
lipoprotein"
/codon_start=1
/transl_table=11
/product="outer membrane protein"
/protein_id="YP_001290082.1"
/db_xref="GI:148825329"
/db_xref="GeneID:5225195"
/translation="MKGKITLFFTALCFGLTGCIAPPKGLEKERFSINSYREISPQDL
TCHCKTVRLGGKIINTTVLANQTKIEVLSLPVSSISGKPFVEFQSDGRFIVYFNGFVE
PENLKERYITVGGQLTGTEKGKIEQADYTYPVVQADKYRIWTLSTTYNYPTDDWDEDD
DWGFFRWRHRPWYVQPEIHYYLN"
misc_feature complement(203028..203570)
/locus_tag="CGSHiEE_01055"
/note="outer membrane lipoprotein, Slp family; Region:
slp; TIGR00752"
/db_xref="CDD:162021"
gene complement(203598..204308)
/locus_tag="CGSHiEE_01060"
/db_xref="GeneID:5225196"
CDS complement(203598..204308)
/locus_tag="CGSHiEE_01060"
/note="COG1214 Inactive homolog of metal-dependent
proteases, putative molecular chaperone"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290083.1"
/db_xref="GI:148825330"
/db_xref="GeneID:5225196"
/translation="MQNLTLLALDTSTEACSVALLYRGVKTHINELAQRTHTKRILPM
IDEILANSGLGLNQVDALAFGRGPGSFTGVRVGAGIAQGLAFGADLPVIPISNLTAMA
QAAFELHQAENVVAAIDARMNEVYFSQVVREKVRSDFGEVFQWREIISEQVCSPKQAI
NQLQNDNAFRVGTGWAAYSQFTEKNLTGSDIELPNALYMLELARVEFLQKHTISALEI
EPIYLRNEVTWKKLPGRE"
misc_feature complement(203637..204293)
/locus_tag="CGSHiEE_01060"
/note="universal bacterial protein YeaZ; Region:
bact_YeaZ; TIGR03725"
/db_xref="CDD:211869"
misc_feature complement(<203754..204245)
/locus_tag="CGSHiEE_01060"
/note="Glycoprotease family; Region: Peptidase_M22;
pfam00814"
/db_xref="CDD:201456"
gene complement(204321..206243)
/locus_tag="CGSHiEE_01065"
/db_xref="GeneID:5225197"
CDS complement(204321..206243)
/locus_tag="CGSHiEE_01065"
/note="COG1199 Rad3-related DNA helicases"
/codon_start=1
/transl_table=11
/product="ATP-dependent helicase"
/protein_id="YP_001290084.1"
/db_xref="GI:148825331"
/db_xref="GeneID:5225197"
/translation="MDYENQIANIFSLNGELSQNIKGFRPRAEQLEMAHAVGKAIQNK
SSLVVEAGTGTGKTFAYLAPALVFGKKTIISTGSKNLQDQLFNRDLPAIKKALNFTGK
IALLKGRANYLCLERLDQVIAQGVLGDKSVLAELSKVRKWNNSTKTGDFTECIELAED
SPIIPQLTSTAESCLGTDCPNYSECYVASARKKALNADLVVVNHHLFFADMAVKESGF
GELIPNAEVIIFDEAHQLPDIASQYFGQSLTSLQLFDLCKDINIVYRTELKDMQQLGT
TSDTLLKVVQDFRLLLGNGSNVRGNWRELYRQSAVKKAFELLQEKIDFLSEVIKLALG
RSQTLDSIFERVESIKIQLKRLSETNIVGYCYWYEGNGRQFGLHITPLTVADKFGAQL
EAKEAAWIFTSATLEVGGTFNHFCQRLGIENATQKILYSPFNYSEQSLLCVPRYLPNT
NQVNTLNSLGEMLLPVIEANKGRCFVLCTSYSMMRGLAEYFREKSHLSILLQGETSKG
KLLEQFIKETHSVLVATSSFWEGVDVRGDALSLVIIDKLPFTAPDEPLLKARIEDCRL
QGGDPFNDIQIPEAVITLKQGVGRLIRDVTDRGVVIICDNRLVMRNYGETFLKSLPNS
SRTRDLNKVIQFLQNK"
misc_feature complement(204330..206213)
/locus_tag="CGSHiEE_01065"
/note="Rad3-related DNA helicases [Transcription / DNA
replication, recombination, and repair]; Region: DinG;
COG1199"
/db_xref="CDD:31392"
misc_feature complement(<205920..206129)
/locus_tag="CGSHiEE_01065"
/note="P-loop containing Nucleoside Triphosphate
Hydrolases; Region: P-loop_NTPase; cl09099"
/db_xref="CDD:213113"
misc_feature complement(205485..>205709)
/locus_tag="CGSHiEE_01065"
/note="DEAD_2; Region: DEAD_2; pfam06733"
/db_xref="CDD:191597"
misc_feature complement(204594..204863)
/locus_tag="CGSHiEE_01065"
/note="Helicase superfamily c-terminal domain; associated
with DEXDc-, DEAD-, and DEAH-box proteins, yeast
initiation factor 4A, Ski2p, and Hepatitis C virus NS3
helicases; this domain is found in a wide variety of
helicases and helicase related proteins; may...; Region:
HELICc; cd00079"
/db_xref="CDD:28960"
misc_feature complement(order(204663..204671,204735..204740,
204798..204809))
/locus_tag="CGSHiEE_01065"
/note="nucleotide binding region [chemical binding]; other
site"
/db_xref="CDD:28960"
gene 206570..206980
/locus_tag="CGSHiEE_01070"
/db_xref="GeneID:5225198"
CDS 206570..206980
/locus_tag="CGSHiEE_01070"
/note="COG0824 Predicted thioesterase"
/codon_start=1
/transl_table=11
/product="thioesterase"
/protein_id="YP_001290085.1"
/db_xref="GI:148825332"
/db_xref="GeneID:5225198"
/translation="MLDNCFSFPVRVYYEDTDAGGVVYHARYLHFFERARTEYLRTLN
FTQQTLLEEQQLAFVVKTLAIDYCVAAKLDDLLMVETEVSEVKGATILFEQRLMRNTL
MLSKATVKVACVDLGKMKPVAFPKEVKAAFHHLK"
misc_feature 206585..206914
/locus_tag="CGSHiEE_01070"
/note="4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes
the final step in the 4-chlorobenzoate degradation pathway
in which 4-chlorobenzoate is converted to
4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT
forms a homotetramer with four active sites; Region: 4HBT;
cd00586"
/db_xref="CDD:48031"
misc_feature order(206666..206668,206741..206743,206747..206749,
206828..206839)
/locus_tag="CGSHiEE_01070"
/note="active site"
/db_xref="CDD:48031"
gene 206997..207683
/locus_tag="CGSHiEE_01075"
/db_xref="GeneID:5225199"
CDS 206997..207683
/locus_tag="CGSHiEE_01075"
/EC_number="6.2.1.3"
/note="COG0811 Biopolymer transport proteins"
/codon_start=1
/transl_table=11
/product="long-chain-fatty-acid--CoA ligase"
/protein_id="YP_001290086.1"
/db_xref="GI:148825333"
/db_xref="GeneID:5225199"
/translation="MTAELNFLDLFLKASIVVQLVIVILISFSIISWAIIIQRSRILT
NALKEARTFEDRFWSGEDLNKLYEGLSNRRDGLTGSEQIFCVGFKEFSRLKQVNPDAP
EAIIKGTMRAMNLAMNREIESLENRVPFLATVASVSPYIGLFGTVWGIMHAFMALSGA
KQATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLSLRVNAIEQDYGNFIDEFTTIL
HRQAFGKAPH"
misc_feature 207009..207665
/locus_tag="CGSHiEE_01075"
/note="MotA/TolQ/ExbB proton channel family; Region:
MotA_ExbB; cl00568"
/db_xref="CDD:212236"
gene 207754..208173
/locus_tag="CGSHiEE_01080"
/db_xref="GeneID:5225109"
CDS 207754..208173
/locus_tag="CGSHiEE_01080"
/note="membrane spanning protein in TolA-TolQ-TolR
complex; involved in the tonB-independent uptake of group
A colicins"
/codon_start=1
/transl_table=11
/product="colicin uptake protein TolR"
/protein_id="YP_001290087.1"
/db_xref="GI:148825334"
/db_xref="GeneID:5225109"
/translation="MARRQRKAIKSEINIVPFLDVLLVLVLIFMATAPIISQSVQVEL
PDSVQSQEVSNEDKVPVILEVAGIGKYAISIGGERQEGLTEEMVTQLSRQEFDKNNNT
LFLVGGAKEVPYEEVIKALNLLHLAGIKSVGLMTNPI"
misc_feature 207760..208170
/locus_tag="CGSHiEE_01080"
/note="colicin uptake protein TolR; Provisional; Region:
PRK11024"
/db_xref="CDD:182908"
gene 208189..209367
/gene="tolA"
/locus_tag="CGSHiEE_01085"
/db_xref="GeneID:5225110"
CDS 208189..209367
/gene="tolA"
/locus_tag="CGSHiEE_01085"
/note="inner membrane component of 7 member Tol-Pal
envelope-spanning complex; involved in maintaining cell
envelope integrity; utilized by colicins and filamentous
phages for import; interacts with TolB, Pal, and through
TolB to various outer membrane porins"
/codon_start=1
/transl_table=11
/product="cell envelope integrity inner membrane protein
TolA"
/protein_id="YP_001290088.1"
/db_xref="GI:148825335"
/db_xref="GeneID:5225110"
/translation="MQNNRQKKGINAFAISILLHFILFGLLILSSLYHTVEIMGGGEG
EGDVIGAVIVDTGTAAQEWGRIQQQKKGQADKQKRPEPVVEEKPPEPNQEEIKHQQEV
QRQEELKRQQEQQRQQEQQRQQEQQRQQEQQRQQEIKKQQEQARQEALEKQKQAEEAK
AKQAAEAAKLKADAEAKRLAAAAKQAEEEAKAKAAEIAAQKAKQEAEAKAKLEAEAKA
KAAAEAKAKAEAEAKAKADAEAKAKAAAEAKAKAATEAKRKADQASLDDFLNGGDIGG
GSASKGGNTNKGGTQGSGAALGSGDGGKVGDQYAGVIKKEIQRRFLKDPNFAGKVCRI
KIQLGRDGTILGYQKISGSDDICSAALSAVARTKKVPAAPSDEIYEKYKSPIIDFDIR
"
misc_feature <209110..209364
/gene="tolA"
/locus_tag="CGSHiEE_01085"
/note="cell envelope integrity inner membrane protein
TolA; Provisional; Region: tolA; PRK09510"
/db_xref="CDD:181920"
misc_feature 209110..209355
/gene="tolA"
/locus_tag="CGSHiEE_01085"
/note="TolA C-terminal; Region: TolA; pfam06519"
/db_xref="CDD:148245"
gene 209409..210692
/gene="tolB"
/locus_tag="CGSHiEE_01090"
/db_xref="GeneID:5225111"
CDS 209409..210692
/gene="tolB"
/locus_tag="CGSHiEE_01090"
/note="forms dimers; may be involved in cell envelope
integrity; interacts with outer membrane proteins and with
the C-terminal domain of inner membrane protein TolA"
/codon_start=1
/transl_table=11
/product="translocation protein TolB"
/protein_id="YP_001290089.1"
/db_xref="GI:148825336"
/db_xref="GeneID:5225111"
/translation="MKLLKRLVSVFAIVLAVGSNAFAGDEVRIVIDEGVDGARPIAVV
PFVGSAPEDISKIVADDLRNSGKFNPIAVSQMPQRPTSAAEVNPEAWSNIGIDAIVIG
QVVPSGNGYSITYQLIDTVGASGTPGTVLMQNSYTVTNKWLRYGAHTVSDEVFEKLTA
IRGAFRTRIAYVVQKNGGSQPYEVRVADYDGYNQFIVNRSAQPIMSPAWSPDGQRLAY
VSFENKKSQLVVQDLNFGARKVVASFQGHNGAPAFSPDGSRLAFASSRDGVLNIYVMG
ANGGTPTQLTSGAGNNTEPAWSPDGNSILFTSDRSGSPQVYRMDASGGSATVVGGRGS
AQISADGKTLVMINGNNNVVKQDLTTGVSEVLSTSFLGESPSLSPNGIMIIYSSTQGL
GKVLQLVSADGRFKASLPGSDGQVKFPAWSPYLTK"
misc_feature 209409..210689
/gene="tolB"
/locus_tag="CGSHiEE_01090"
/note="translocation protein TolB; Provisional; Region:
tolB; PRK01742"
/db_xref="CDD:179329"
misc_feature 209487..209768
/gene="tolB"
/locus_tag="CGSHiEE_01090"
/note="TolB amino-terminal domain; Region: TolB_N;
pfam04052"
/db_xref="CDD:202869"
misc_feature 209997..210092
/gene="tolB"
/locus_tag="CGSHiEE_01090"
/note="WD40-like Beta Propeller Repeat; Region: PD40;
pfam07676"
/db_xref="CDD:203719"
misc_feature 210120..210230
/gene="tolB"
/locus_tag="CGSHiEE_01090"
/note="WD40-like Beta Propeller Repeat; Region: PD40;
pfam07676"
/db_xref="CDD:203719"
misc_feature 210252..210362
/gene="tolB"
/locus_tag="CGSHiEE_01090"
/note="WD40-like Beta Propeller Repeat; Region: PD40;
pfam07676"
/db_xref="CDD:203719"
gene 210716..211177
/locus_tag="CGSHiEE_01095"
/db_xref="GeneID:5225112"
CDS 210716..211177
/locus_tag="CGSHiEE_01095"
/note="COG2885 Outer membrane protein and related
peptidoglycan-associated (lipo)proteins"
/codon_start=1
/transl_table=11
/product="outer membrane protein P6"
/protein_id="YP_001290090.1"
/db_xref="GI:148825337"
/db_xref="GeneID:5225112"
/translation="MNKFVKSLLVAGSVAALAACSSSNNDAAGNGAAQTFGGYSVADL
QQRYNTVYFGFDKYDITGEYVQILDAHAAYLNATPAAKVLVEGNTDERGTPEYNIALG
QRRADAVKGYLAGKGVDAGKLGTVSYGEEKPAVLGHDEAAYSKNRRAVLAY"
misc_feature 210863..211168
/locus_tag="CGSHiEE_01095"
/note="Peptidoglycan binding domains similar to the
C-terminal domain of outer-membrane protein OmpA; Region:
OmpA_C-like; cd07185"
/db_xref="CDD:143586"
misc_feature order(210878..210883,210980..210985,210992..210994,
211004..211009,211016..211018,211142..211144,
211154..211156)
/locus_tag="CGSHiEE_01095"
/note="ligand binding site [chemical binding]; other site"
/db_xref="CDD:143586"
gene 211332..211407
/locus_tag="CGSHiEE_t09344"
/db_xref="GeneID:5542109"
tRNA 211332..211407
/locus_tag="CGSHiEE_t09344"
/product="tRNA-Lys"
/db_xref="GeneID:5542109"
gene 211431..211506
/locus_tag="CGSHiEE_t09346"
/db_xref="GeneID:5542093"
tRNA 211431..211506
/locus_tag="CGSHiEE_t09346"
/product="tRNA-Lys"
/db_xref="GeneID:5542093"
misc_feature 211617..212343
/note="potential frameshift: common BLAST hit:
gi|113460425|ref|YP_718487.1| possible tRNA/rRNA
methyltransferase [Haemophilus somnus 129PT]"
gene 212396..212848
/locus_tag="CGSHiEE_01110"
/db_xref="GeneID:5225113"
CDS 212396..212848
/locus_tag="CGSHiEE_01110"
/note="COG1959 Predicted transcriptional regulator"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290091.1"
/db_xref="GI:148825338"
/db_xref="GeneID:5225113"
/translation="MKLTSKGRYAVTAVLDIALNADGGPVSLADISERQHISLSYLEQ
LFAKLRKGGLVKSVRGPGGGYQLGLPSEQISVGMIIAAVNENIHVTKCLGRENCKNGV
ECLTHELWQDLSLRIESFLNEITLAELVNKRNVKRQSHRDFNNLLVNQ"
misc_feature 212396..212800
/locus_tag="CGSHiEE_01110"
/note="iron-sulfur cluster assembly transcription factor
IscR; Region: IscR; TIGR02010"
/db_xref="CDD:131065"
misc_feature 212396..212788
/locus_tag="CGSHiEE_01110"
/note="Rrf2 family protein; Region: rrf2_super; TIGR00738"
/db_xref="CDD:129821"
gene 212916..214130
/gene="tolB"
/locus_tag="CGSHiEE_01115"
/db_xref="GeneID:5225031"
CDS 212916..214130
/gene="tolB"
/locus_tag="CGSHiEE_01115"
/note="catalyzes the removal of elemental sulfur from
cysteine to produce alanine; involved in NAD biosynthesis"
/codon_start=1
/transl_table=11
/product="cysteine desulfurase"
/protein_id="YP_001290092.1"
/db_xref="GI:148825339"
/db_xref="GeneID:5225031"
/translation="MKLPIYLDYAATCPVDERVAKKMMAFLTIDGTFGNPASRSHKFG
WQAEEAVDIARNQIADLIGADSREIVFTSGATESDNLAIKGAAHFYQTKGKHILTCKT
EHKAVLDTCRQLEREGFEVTYLSPEADGLIDLEKFKAALRPDTILASIMHANNEIGVL
QDIKAIGELCRANKTIFHVDATQSVGKVEINLEELAVDLMSMSSHKLYGPKGVGALYV
RRKPRVRLEAIIHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMASEMPRLKALRDR
LYNGLKDIEETYVNGSMEHRLDSNLNISFNYVEGESLMMALRDIAVSSGSACTSASLE
PSYVLRALGLNDELAHSSIRFTLGRYTTEEEIDYTINLMKGAVEKLRALSPLWDMFKE
GIDLNTIEWSAH"
misc_feature 212916..214127
/gene="tolB"
/locus_tag="CGSHiEE_01115"
/note="cysteine desulfurase; Provisional; Region:
PRK14012"
/db_xref="CDD:184450"
misc_feature 212931..213986
/gene="tolB"
/locus_tag="CGSHiEE_01115"
/note="cysteine desulfurase DndA; Region: DNA_S_dndA;
TIGR03235"
/db_xref="CDD:163191"
misc_feature order(213138..213143,213150..213152,213369..213371,
213453..213455,213462..213464,213522..213524,
213531..213533)
/gene="tolB"
/locus_tag="CGSHiEE_01115"
/note="pyridoxal 5'-phosphate binding pocket [chemical
binding]; other site"
/db_xref="CDD:99742"
misc_feature 213531..213533
/gene="tolB"
/locus_tag="CGSHiEE_01115"
/note="catalytic residue [active]"
/db_xref="CDD:99742"
gene 214189..214569
/locus_tag="CGSHiEE_01120"
/db_xref="GeneID:5225032"
CDS 214189..214569
/locus_tag="CGSHiEE_01120"
/note="COG0822 NifU homolog involved in Fe-S cluster
formation"
/codon_start=1
/transl_table=11
/product="scaffold protein"
/protein_id="YP_001290093.1"
/db_xref="GI:148825340"
/db_xref="GeneID:5225032"
/translation="MAYSEKVIDHYENPRNVGSLDKKDSNVGTGMVGAPACGDVMQLQ
IKVDDNGIIEDAKFKTYGCGSAIASSSLITEWVKGKSLEEAGAIKNSQIAEELELPPV
KVHCSILAEDAIKAAIADYKAKQG"
misc_feature 214189..214515
/locus_tag="CGSHiEE_01120"
/note="NifU homolog involved in Fe-S cluster formation
[Energy production and conversion]; Region: IscU; COG0822"
/db_xref="CDD:31164"
misc_feature 214195..214515
/locus_tag="CGSHiEE_01120"
/note="Iron-sulfur cluster scaffold-like proteins; Region:
IscU_like; cd06664"
/db_xref="CDD:143480"
misc_feature order(214195..214203,214210..214215,214297..214302,
214375..214377,214381..214383,214492..214497,
214501..214506)
/locus_tag="CGSHiEE_01120"
/note="trimerization site [polypeptide binding]; other
site"
/db_xref="CDD:143480"
misc_feature order(214297..214299,214375..214377,214504..214506)
/locus_tag="CGSHiEE_01120"
/note="active site"
/db_xref="CDD:143480"
gene 214627..214950
/locus_tag="CGSHiEE_01125"
/db_xref="GeneID:5224949"
CDS 214627..214950
/locus_tag="CGSHiEE_01125"
/note="COG0316 Uncharacterized conserved protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290094.1"
/db_xref="GI:148825341"
/db_xref="GeneID:5224949"
/translation="MGITLTEKAAQRVKAFLDNRGKGIGLRLGVKTSGCSGLAYVLEF
VDVLNSEDQVFEQHGVNIIVDPKSLVYLNGIELDYVKEGLNEGFKYNNPNVKESCGCG
ESFHV"
misc_feature 214633..214947
/locus_tag="CGSHiEE_01125"
/note="iron-sulfur cluster assembly protein IscA; Region:
IscA; TIGR02011"
/db_xref="CDD:211707"
gene 214991..215488
/gene="hscB"
/locus_tag="CGSHiEE_01130"
/db_xref="GeneID:5224950"
CDS 214991..215488
/gene="hscB"
/locus_tag="CGSHiEE_01130"
/note="J-type co-chaperone that regulates the ATPase and
peptide-binding activity of Hsc66 chaperone; may function
in biogenesis of iron-sulfur proteins"
/codon_start=1
/transl_table=11
/product="co-chaperone HscB"
/protein_id="YP_001290095.1"
/db_xref="GI:148825342"
/db_xref="GeneID:5224950"
/translation="MPVDFQLDEKVLNARYLKLQKALHPDNFVSSSALEQRVAMQKST
EVNDALKTLKDPILRAEAIIALNTGEQLDLEQKSTQDVAFLMQQLQWREQLEDVESQQ
DERALNVFAKEIKQETQSLLTALFESLKSQQWARASQYCDKLRFTHKLSEEIERVEER
IFELD"
misc_feature 214997..215173
/gene="hscB"
/locus_tag="CGSHiEE_01130"
/note="DnaJ domain; Region: DnaJ; pfam00226"
/db_xref="CDD:201096"
misc_feature 215003..215443
/gene="hscB"
/locus_tag="CGSHiEE_01130"
/note="Fe-S protein assembly co-chaperone HscB; Region:
hscB; TIGR00714"
/db_xref="CDD:211601"
misc_feature order(215060..215068,215108..215110,215117..215122,
215129..215134)
/gene="hscB"
/locus_tag="CGSHiEE_01130"
/note="HSP70 interaction site [polypeptide binding]; other
site"
/db_xref="CDD:99751"
misc_feature 215225..215440
/gene="hscB"
/locus_tag="CGSHiEE_01130"
/note="HSCB C-terminal oligomerisation domain; Region:
HSCB_C; pfam07743"
/db_xref="CDD:203753"
gene 215539..216225
/locus_tag="CGSHiEE_01135"
/db_xref="GeneID:5224951"
CDS 215539..216225
/locus_tag="CGSHiEE_01135"
/note="COG1076 DnaJ-domain-containing proteins 1"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290096.1"
/db_xref="GI:148825343"
/db_xref="GeneID:5224951"
/translation="MQTLEQLTSPEHSAWITLSQWIDNARNHCEVIKKDQSSAERELF
TMQMPTSSPMGAVIYETGGILIHYGWLRILGSGSFKLPRGLMDWNFSKSFSESGEKPK
YLLVADDVIGGYFALNGGSLGNNIGKIYYYSSKDLTWHNLNFTYTEFLAWALNGDVEA
FYQGLFWKNWQDDVKQLDGNQVFVFTPDLNQDRKIAIDERQKQEVNIETHYQANFAEK
NKFDLAYSVA"
misc_feature 215548..216171
/locus_tag="CGSHiEE_01135"
/note="Protein of unknown function DUF2625; Region:
DUF2625; pfam10946"
/db_xref="CDD:151393"
gene 216244..218103
/gene="hscA"
/locus_tag="CGSHiEE_01140"
/db_xref="GeneID:5224952"
CDS 216244..218103
/gene="hscA"
/locus_tag="CGSHiEE_01140"
/note="involved in the maturation of iron-sulfur
cluster-containing proteins"
/codon_start=1
/transl_table=11
/product="chaperone protein HscA"
/protein_id="YP_001290097.1"
/db_xref="GI:148825344"
/db_xref="GeneID:5224952"
/translation="MALLQIAEPGQAAAPHQHRLAVGIDLGTTNSLVASVRSGQSVIL
NDEQERSLVPSVVHYGVEEKKVGLEAFEQASLDPKNTVISVKRLIGRSLPDVQSRYSS
LPYEFVASENGLPLIITAQGPKSPIEVSSDILLRLNHIAEQRLGGELSGVVITVPAYF
DDAQRQSTKDAARLAGLNVLRLLNEPTAAALAYGLDSGQEGIIAVYDLGGGTFDISIL
RLSKGIFEVLATGGDTALGGDDFDHLIADWVIEQTKLKPQTANQQRELITLANQAKIT
LTNEKSAVISWQDFSVEISREQFNELIYPLVKRSLLTCRRALKDANVESEEVQAVVMV
GGSTRVPYVREQVGEFFGKTPLTSIDPDKVVALGAAIQADILVGNKTDSDMLLLDVVP
LSLGIETMGGLVEKIIPRNTTIPVARAQEFTTFKDGQTAMSVHVLQGERELVDDCRSL
GRFTLRGIPPMAAGAAHIRVTYQVDADGLLSVTAMEKSTKVQASIQIKPSYGLTDEEV
TAMIKSSFDNAQEDLQARELAEQRVEADRVIESVIVALQADGAELLSTDEFHHIETVL
KQLMDVKQGSDRDAIAQGIKALDTATQEFAARRMNASINKALTGKNLSDIENP"
misc_feature 216244..218091
/gene="hscA"
/locus_tag="CGSHiEE_01140"
/note="chaperone protein HscA; Provisional; Region: hscA;
PRK05183"
/db_xref="CDD:179957"
misc_feature 216301..217365
/gene="hscA"
/locus_tag="CGSHiEE_01140"
/note="Nucleotide-binding domain of HscA and similar
proteins; Region: HscA_like_NBD; cd10236"
/db_xref="CDD:212678"
misc_feature order(216316..216318,216322..216333,216499..216501,
216712..216714,216796..216798,216862..216879,
216883..216885,216955..216960,217054..217056,
217063..217068,217246..217254,217258..217263,
217327..217329)
/gene="hscA"
/locus_tag="CGSHiEE_01140"
/note="nucleotide binding site [chemical binding]; other
site"
/db_xref="CDD:212678"
misc_feature order(216385..216387,216433..216435,216445..216447,
216454..216459,216670..216675,217024..217026,
217033..217038,217045..217047,217057..217059,
217093..217095,217099..217104)
/gene="hscA"
/locus_tag="CGSHiEE_01140"
/note="putative NEF/HSP70 interaction site [polypeptide
binding]; other site"
/db_xref="CDD:212678"
misc_feature order(216727..216732,216736..216741,216784..216789,
216793..216795,216916..216927)
/gene="hscA"
/locus_tag="CGSHiEE_01140"
/note="SBD interface [polypeptide binding]; other site"
/db_xref="CDD:212678"
gene 218143..218484
/locus_tag="CGSHiEE_01145"
/db_xref="GeneID:5224953"
CDS 218143..218484
/locus_tag="CGSHiEE_01145"
/note="COG0633 Ferredoxin"
/codon_start=1
/transl_table=11
/product="ferredoxin, 2Fe-2S"
/protein_id="YP_001290098.1"
/db_xref="GI:148825345"
/db_xref="GeneID:5224953"
/translation="MPKVIFLPNEDFCPEGMVVDAATGDNLLEVAHNAGVEIHHACDG
SCACTTCHVIVREGFDSLNETSDQEEDMLDKAWGLEMDSRLSCQCVVGNEDLVVEIPK
YNLNHANEAAH"
misc_feature 218182..218439
/locus_tag="CGSHiEE_01145"
/note="2Fe-2S iron-sulfur cluster binding domain.
Iron-sulfur proteins play an important role in electron
transfer processes and in various enzymatic reactions. The
family includes plant and algal ferredoxins, which act as
electron carriers in photosynthesis...; Region: fer2;
cd00207"
/db_xref="CDD:29262"
misc_feature order(218254..218259,218266..218268,218275..218277,
218284..218295,218398..218403)
/locus_tag="CGSHiEE_01145"
/note="catalytic loop [active]"
/db_xref="CDD:29262"
misc_feature order(218266..218268,218284..218286,218293..218295,
218401..218403)
/locus_tag="CGSHiEE_01145"
/note="iron binding site [ion binding]; other site"
/db_xref="CDD:29262"
gene 218484..218678
/locus_tag="CGSHiEE_01150"
/db_xref="GeneID:5224895"
CDS 218484..218678
/locus_tag="CGSHiEE_01150"
/note="COG2975 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290099.1"
/db_xref="GI:148825346"
/db_xref="GeneID:5224895"
/translation="MKWTDAQLIAEELYDRNPDLDPKTVRFTDLHKWICELEDFDDDP
NKSNESILEAILLKWLDEFE"
misc_feature 218484..218675
/locus_tag="CGSHiEE_01150"
/note="Iron-sulphur cluster assembly; Region:
Fe-S_assembly; pfam04384"
/db_xref="CDD:146824"
gene complement(218729..219343)
/gene="hscA"
/locus_tag="CGSHiEE_01155"
/db_xref="GeneID:5224896"
CDS complement(218729..219343)
/gene="hscA"
/locus_tag="CGSHiEE_01155"
/note="COG2976 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290100.1"
/db_xref="GI:148825347"
/db_xref="GeneID:5224896"
/translation="MAYSIEEEQEINQLKEWWKENGKTIIVAFILGVGGMFGWRYWQA
HQAEQIAQASAQYDALINSVQQDEQAKKANIEQFVQANSKTAYAVFALLDEAKKATEK
QDFSAAEANLNQALTQSQDEVLTSIVALRLSAVQFQLGQLDNALSTLNQVKGESFNAR
KAILTGDIQIAKGDKVAAKNSFEQAQQSGSQLEQQMAKMKLNNL"
misc_feature complement(218732..219343)
/gene="hscA"
/locus_tag="CGSHiEE_01155"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG2976"
/db_xref="CDD:32795"
misc_feature complement(219197..219319)
/gene="hscA"
/locus_tag="CGSHiEE_01155"
/note="Uncharacterized protein conserved in bacteria
(DUF2133); Region: DUF2133; pfam09976"
/db_xref="CDD:204361"
gene complement(219361..220632)
/gene="hisS"
/locus_tag="CGSHiEE_01160"
/db_xref="GeneID:5224897"
CDS complement(219361..220632)
/gene="hisS"
/locus_tag="CGSHiEE_01160"
/EC_number="6.1.1.21"
/note="catalyzes a two-step reaction, first charging a
histidine molecule by linking its carboxyl group to the
alpha-phosphate of ATP, followed by transfer of the
aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA
synthetase; forms homodimers; some organisms have a
paralogous gene, hisZ, that is similar to hisS and
produces a protein that performs the first step in
histidine biosynthesis along with HisG"
/codon_start=1
/transl_table=11
/product="histidyl-tRNA synthetase"
/protein_id="YP_001290101.1"
/db_xref="GI:148825348"
/db_xref="GeneID:5224897"
/translation="MAKTIQAIRGMNDCAPTESPLWQWIEAQVRNVLNSYGYSEVRMP
IVESTPLFARAIGEVTDVVSKEMYTFWDNDEQLTLRPEGTAGCVRAAIEHGWIYNNEQ
RLWYIGPMFRHERPQKGRYRQFHQAGVEVFGIANPKIDAELIMLTYRLWKALGIDQYV
TLQLNSIGSLEARANYRSALVGFLENHQDLMSDEEKDRLVKNPLRILDTKNPELQKVL
DNAPKLLDYLDDESREHFEQLCSLLDAVGIQYEINPKLVRGLDYYNKTVFEWVTSALG
AQGTVCGGGRYDGLVEQLGGHATPSIGFAMGLERLVLLVQEVNPNVPVKSAVDIYVVY
QGEGTTLAAFELAEKVRSELPHLNTMLHCSGGNFKKQFKRADKSGATLALVIGESEVQ
NKQVVVKHLQGGADQQTLDLVNIIDYIQTQF"
misc_feature complement(219364..220623)
/gene="hisS"
/locus_tag="CGSHiEE_01160"
/note="histidyl-tRNA synthetase; Reviewed; Region: hisS;
PRK00037"
/db_xref="CDD:178812"
misc_feature complement(219685..220581)
/gene="hisS"
/locus_tag="CGSHiEE_01160"
/note="Class II Histidinyl-tRNA synthetase (HisRS)-like
catalytic core domain. HisRS is a homodimer. It is
responsible for the attachment of histidine to the 3' OH
group of ribose of the appropriate tRNA. This domain is
primarily responsible for ATP-dependent...; Region:
HisRS-like_core; cd00773"
/db_xref="CDD:73226"
misc_feature complement(order(219721..219726,219778..219780,
220198..220200,220207..220209,220219..220221,
220243..220245,220264..220269,220351..220356,
220363..220368,220381..220383,220387..220389,
220420..220425,220495..220515,220528..220530,
220564..220566))
/gene="hisS"
/locus_tag="CGSHiEE_01160"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:73226"
misc_feature complement(220495..220521)
/gene="hisS"
/locus_tag="CGSHiEE_01160"
/note="motif 1; other site"
/db_xref="CDD:73226"
misc_feature complement(order(219703..219705,219712..219714,
219721..219723,219778..219780,219793..219795,
219844..219849,219853..219855,219859..219861,
220243..220245,220255..220257,220261..220263,
220270..220272,220291..220293,220297..220299,
220381..220383,220387..220389))
/gene="hisS"
/locus_tag="CGSHiEE_01160"
/note="active site"
/db_xref="CDD:73226"
misc_feature complement(220288..220302)
/gene="hisS"
/locus_tag="CGSHiEE_01160"
/note="motif 2; other site"
/db_xref="CDD:73226"
misc_feature complement(order(219703..219705,219712..219726))
/gene="hisS"
/locus_tag="CGSHiEE_01160"
/note="motif 3; other site"
/db_xref="CDD:73226"
misc_feature complement(219373..219654)
/gene="hisS"
/locus_tag="CGSHiEE_01160"
/note="HisRS Histidyl-anticodon binding domain. HisRS
belongs to class II aminoacyl-tRNA synthetases (aaRS).
This alignment contains the anticodon binding domain,
which is responsible for specificity in tRNA-binding, so
that the activated amino acid is...; Region:
HisRS_anticodon; cd00859"
/db_xref="CDD:29799"
misc_feature complement(order(219436..219438,219442..219444,
219472..219474,219496..219498,219514..219516,
219625..219630))
/gene="hisS"
/locus_tag="CGSHiEE_01160"
/note="anticodon binding site; other site"
/db_xref="CDD:29799"
gene complement(220642..220710)
/locus_tag="CGSHiEE_01165"
/db_xref="GeneID:5224898"
CDS complement(220642..220710)
/locus_tag="CGSHiEE_01165"
/note="COG0124 Histidyl-tRNA synthetase"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290102.1"
/db_xref="GI:148825349"
/db_xref="GeneID:5224898"
/translation="MNQLEAKIRAKIARQDPKNRII"
gene complement(220710..221747)
/locus_tag="CGSHiEE_01170"
/db_xref="GeneID:5224899"
CDS complement(220710..221747)
/locus_tag="CGSHiEE_01170"
/note="COG0821 Enzyme involved in the deoxyxylulose
pathway of isoprenoid biosynthesis"
/codon_start=1
/transl_table=11
/product="4-hydroxy-3-methylbut-2-en-1-yl diphosphate
synthase"
/protein_id="YP_001290103.1"
/db_xref="GI:148825350"
/db_xref="GeneID:5224899"
/translation="MSAFQPTIKRRESTKIYVGNVPIGGDAPIAVQSMTNTRTTDVEA
TVAQIKSLERVGADIVRVSVPTMDAAEAFKQIKQQVNVPLVADIHFDYRIALKVAEYG
VDCLRINPGNIGREDRIRAVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPEALLE
SALRHVEILDRLNFNQFKVSVKASDVFLAVEAYRLLAKAIKQPLHLGITEAGGARAGA
VKSAVGLGMLLAEGIGDTLRVSLAADPIEEIKVGFDILKSLRIRSRGINFIACPTCSR
QEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSDLGVTGGNKKAVIILTA
NVKKSVLITKI"
misc_feature complement(220758..221732)
/locus_tag="CGSHiEE_01170"
/note="4-hydroxy-3-methylbut-2-en-1-yl diphosphate
synthase; Reviewed; Region: ispG; PRK00366"
/db_xref="CDD:178989"
misc_feature complement(<220977..221720)
/locus_tag="CGSHiEE_01170"
/note="4-hydroxy-3-methylbut-2-en-1-yl diphosphate
synthase; Validated; Region: PRK00694"
/db_xref="CDD:134348"
misc_feature complement(220779..>221096)
/locus_tag="CGSHiEE_01170"
/note="4-hydroxy-3-methylbut-2-en-1-yl diphosphate
synthase; Validated; Region: PRK00694"
/db_xref="CDD:134348"
gene complement(221756..222667)
/locus_tag="CGSHiEE_01175"
/db_xref="GeneID:5224752"
CDS complement(221756..222667)
/locus_tag="CGSHiEE_01175"
/note="COG1426 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290104.1"
/db_xref="GI:148825351"
/db_xref="GeneID:5224752"
/translation="MNPTTEQVLSPGEIFRQTREALNLSLEDVAKEITLRPSILEQLE
NNEFIQKSTPAIFVKGYVRSYAKFLRLPDSVWENIVFAETEKNDLGKNARSTRAVNQY
SSHNRWIGRLTAIVFVMVIGMTGLWWWQSYQQNTQERDDLVQSYVASTENNQPATALV
TTEESNKTAPETAAPVSQPVEITNNLLPKIAQENSVSLPKNNEKSVSDIQSAVENPSI
SPTLPIAKGDLVIEILTHSSWISVKDNARHVLAQKEYKQGEILTFNGNEFSLIVGAPS
NVRITYKGENYPLKVDGRVAKFKLSQP"
misc_feature complement(221852..222646)
/locus_tag="CGSHiEE_01175"
/note="Predicted transcriptional regulator contains
Xre-like HTH domain [Function unknown]; Region: COG1426"
/db_xref="CDD:31615"
misc_feature complement(222452..222634)
/locus_tag="CGSHiEE_01175"
/note="Helix-turn-helix XRE-family like proteins.
Prokaryotic DNA binding proteins belonging to the
xenobiotic response element family of transcriptional
regulators; Region: HTH_XRE; cd00093"
/db_xref="CDD:28977"
misc_feature complement(order(222533..222535,222608..222610,
222620..222622))
/locus_tag="CGSHiEE_01175"
/note="non-specific DNA binding site [nucleotide binding];
other site"
/db_xref="CDD:28977"
misc_feature complement(order(222536..222538,222611..222613))
/locus_tag="CGSHiEE_01175"
/note="salt bridge; other site"
/db_xref="CDD:28977"
misc_feature complement(order(222530..222535,222545..222547,
222554..222556,222587..222592))
/locus_tag="CGSHiEE_01175"
/note="sequence-specific DNA binding site [nucleotide
binding]; other site"
/db_xref="CDD:28977"
misc_feature complement(221768..221956)
/locus_tag="CGSHiEE_01175"
/note="Domain of unknown function (DUF4115); Region:
DUF4115; pfam13464"
/db_xref="CDD:205642"
gene complement(222739..223278)
/gene="ispG"
/locus_tag="CGSHiEE_01180"
/db_xref="GeneID:5224753"
CDS complement(222739..223278)
/gene="ispG"
/locus_tag="CGSHiEE_01180"
/note="COG3063 Tfp pilus assembly protein PilF"
/codon_start=1
/transl_table=11
/product="4-hydroxy-3-methylbut-2-en-1-yl diphosphate
synthase"
/protein_id="YP_001290105.1"
/db_xref="GI:148825352"
/db_xref="GeneID:5224753"
/translation="MKTISKQLSAVIFPFIFSACVSQSASNLNHQAAAKARVELALSY
LQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGEIENAHREYEIAVNLNHKQG
DVHNNFGTFLCSQKKFEQAQQQFELALNSPNYYHQADTFENIVLCAYSAQKMDIYQQT
LEKLRQIDGKRAEKFNSLK"
misc_feature complement(222985..223179)
/gene="ispG"
/locus_tag="CGSHiEE_01180"
/note="TPR repeat; Region: TPR_11; pfam13414"
/db_xref="CDD:205592"
misc_feature complement(<222940..223164)
/gene="ispG"
/locus_tag="CGSHiEE_01180"
/note="Tetratricopeptide repeat domain; typically contains
34 amino acids
[WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
a variety of organisms including bacteria, cyanobacteria,
yeast, fungi; Region: TPR; cl02429"
/db_xref="CDD:207591"
misc_feature complement(order(222946..222951,222958..222963,
223039..223044,223051..223056,223060..223065,
223150..223155,223162..223164))
/gene="ispG"
/locus_tag="CGSHiEE_01180"
/note="binding surface"
/db_xref="CDD:29151"
misc_feature complement(order(222952..222954,222997..222999,
223006..223008,223018..223020,223054..223056,
223099..223101,223108..223110,223120..223122,
223156..223158))
/gene="ispG"
/locus_tag="CGSHiEE_01180"
/note="TPR motif; other site"
/db_xref="CDD:29151"
gene complement(223379..224530)
/locus_tag="CGSHiEE_01185"
/db_xref="GeneID:5224754"
CDS complement(223379..224530)
/locus_tag="CGSHiEE_01185"
/note="23S rRNA m2A2503 methyltransferase; methylates the
C2 position of the A2530 nucleotide in 23S rRNA; may be
involved in antibiotic resistance"
/codon_start=1
/transl_table=11
/product="ribosomal RNA large subunit methyltransferase N"
/protein_id="YP_001290106.1"
/db_xref="GI:148825353"
/db_xref="GeneID:5224754"
/translation="MSELLSVQSDAPAKKINLMDLTRQQMREFFKELGEKPFRADQLV
KWIYHFGEDNFDNMTNINKKLREKLKAVAEIKAPEVAVEQRSADGTIKWAMQVGEQQV
ETVYIPEADRATLCVSSQVGCALACTFCSTAQQGFNRNLTVSEIIGQVWRASKIIGNF
GVTGVRPITNVVMMGMGEPLLNVANVVPAMEIMLDDFAYGLSKRRVTLSTSGVVPALD
NLSKMIDVALAISLHAPNDELRDEIVPINKKYNIKTLIDSVNRYLTVSNANHGKVTIE
YVMLDHVNDGVEHAHQLADVLKNTPCKINLIPWNPFPEAPYAKSSNTRIDRFQKTLME
YDFTVIIRKTRGDDIDAACGQLAGDVIDRTKRTAMKRQFGQNIGVTEVN"
misc_feature complement(223385..224494)
/locus_tag="CGSHiEE_01185"
/note="ribosomal RNA large subunit methyltransferase N;
Provisional; Region: PRK11194"
/db_xref="CDD:183031"
misc_feature complement(223565..224167)
/locus_tag="CGSHiEE_01185"
/note="Radical SAM superfamily. Enzymes of this family
generate radicals by combining a 4Fe-4S cluster and
S-adenosylmethionine (SAM) in close proximity. They are
characterized by a conserved CxxxCxxC motif, which
coordinates the conserved iron-sulfur cluster; Region:
Radical_SAM; cd01335"
/db_xref="CDD:100105"
misc_feature complement(order(223604..223609,223697..223699,
223838..223840,223898..223906,223997..224002,
224006..224008,224138..224146,224150..224152,
224156..224158,224162..224164))
/locus_tag="CGSHiEE_01185"
/note="FeS/SAM binding site; other site"
/db_xref="CDD:100105"
gene 224777..225655
/locus_tag="CGSHiEE_01190"
/db_xref="GeneID:5224755"
CDS 224777..225655
/locus_tag="CGSHiEE_01190"
/note="COG1686 D-alanyl-D-alanine carboxypeptidase"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290107.1"
/db_xref="GI:148825354"
/db_xref="GeneID:5224755"
/translation="MFKKALFILSLCPSFLLAQSYVVYDFTHNRVLESYAPDSIQPIA
SVTKLMTANVFLENNKNPNCRIAITKEDTDRIKGTGTKLPKNIPISCNELLKAMLVHS
DNYAAHALSRAAGISRRQFINKMNEKAHQLGMYSTRFHDSSGLSSYNISSPMDLVKLA
KYSLNKADIKRLSNLSATYIQAGKYKLYIKNTNKLVRDEIFDAAVNKTGYIQESGYNL
VFINKHLCKNATIGVISLNNTSSAYRSSFTKSKLEKFGCTALNGRTIRDVAGEAQYED
GYDEVGFNTLIQKLSK"
misc_feature 224777..>225613
/locus_tag="CGSHiEE_01190"
/note="D-alanyl-D-alanine carboxypeptidase [Cell envelope
biogenesis, outer membrane]; Region: DacC; COG1686"
/db_xref="CDD:31872"
misc_feature 224876..>225253
/locus_tag="CGSHiEE_01190"
/note="Penicillin binding protein transpeptidase domain;
Region: Transpeptidase; cl01009"
/db_xref="CDD:207282"
gene complement(225749..226213)
/locus_tag="CGSHiEE_01195"
/db_xref="GeneID:5224756"
CDS complement(225749..226213)
/locus_tag="CGSHiEE_01195"
/note="COG3064 Membrane protein involved in colicin
uptake"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290108.1"
/db_xref="GI:148825355"
/db_xref="GeneID:5224756"
/translation="MKKAFWLVLSSAIVLAACDDKPKMTEQTKITDQAKMTAEQPAQK
PVLINYKQIALDKSQQAIDTVKVAQDKSVQANEAVKVAMQKQQEAEIALSQGGEEAEK
LSKQKMDESNAAAELALKLSEESKAASALSIQLSKEAEDAANKANQQAQAEK"
gene 226520..227401
/locus_tag="CGSHiEE_01200"
/db_xref="GeneID:5224757"
CDS 226520..227401
/locus_tag="CGSHiEE_01200"
/note="COG0803 ABC-type metal ion transport system,
periplasmic component/surface adhesin"
/codon_start=1
/transl_table=11
/product="putative periplasmic chelated iron binding
protein"
/protein_id="YP_001290109.1"
/db_xref="GI:148825356"
/db_xref="GeneID:5224757"
/translation="MRNSFKIMTALALGLFAMQANAKFKVVTTFTVIQDIAQNVAGNA
ATVESITKPGAEIHEYEPTPKDIVKAQSADLILWNGLNLERWFERFFQNVKDKPAVVV
TEGIQPLSIYEGPYKDVPNPHAWMSPSNALIYIENIKNALVKYDPQNAAVYEKNAADY
AQKIKQLDEPLRAKLAQIPEAQRWLVTSEGAFSYLAKDYNLKEGYLWPINAEQQGTPQ
QVRKVIDLVRKNNIPVVFSESTISAKPAQQVAKESGAKYGGVLYVDSLSAKNGPVPTY
IDLLNVTVSTIVKGFGK"
misc_feature 226541..227395
/locus_tag="CGSHiEE_01200"
/note="Metal binding protein PsaA. These proteins have
been shown to function as initial receptors in ABC
transport of Mn2+ and as surface adhesins in some
eubacterial species. They belong to the TroA superfamily
of periplasmic metal binding proteins that...; Region:
PsaA; cd01137"
/db_xref="CDD:29740"
misc_feature 226595..227392
/locus_tag="CGSHiEE_01200"
/note="Periplasmic solute binding protein family; Region:
SBP_bac_9; pfam01297"
/db_xref="CDD:201717"
misc_feature order(226691..226693,226886..226888,227084..227086,
227309..227311)
/locus_tag="CGSHiEE_01200"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:29740"
gene 227401..228321
/locus_tag="CGSHiEE_01205"
/db_xref="GeneID:5224717"
CDS 227401..228321
/locus_tag="CGSHiEE_01205"
/note="COG1121 ABC-type Mn/Zn transport systems, ATPase
component"
/codon_start=1
/transl_table=11
/product="iron (chelated) transporter ATP-binding protein"
/protein_id="YP_001290110.1"
/db_xref="GI:148825357"
/db_xref="GeneID:5224717"
/translation="MDSFSTSIWVNDVTVRYNNGHTAIHNMTFSLNSGTICALVGVNG
SGKSTLFKSIMGLVKPQQGEIKLCDLPISQALKRNLVAYVPQSEEVDWQFPVSVYDVV
MMGRYGYMNFLRIPKAIDKQKVQEAMQRVNIEHLAHRQIGELSGGQKKRVFLARALAQ
QSPIILLDEPFTGVDVKTENAIVDLLQQLREEGHLILVSTHNLGSVPDFCDQVVMINR
TVIAAGKTEDTFNQHNLEIVFGGVLRHIKLLGENLHNDEDKRSVTVLTDDEKAVVFYG
ETKQDPPAPTTQNCHFEDCPYKSAVKNKRD"
misc_feature 227413..228219
/locus_tag="CGSHiEE_01205"
/note="manganese/iron transporter ATP-binding protein;
Provisional; Region: PRK15056"
/db_xref="CDD:185016"
misc_feature 227425..228072
/locus_tag="CGSHiEE_01205"
/note="ATP-binding cassette domain of the metal-type
transporters; Region: ABC_Metallic_Cations; cd03235"
/db_xref="CDD:213202"
gene 228325..229173
/locus_tag="CGSHiEE_01210"
/db_xref="GeneID:5224718"
CDS 228325..229173
/locus_tag="CGSHiEE_01210"
/note="COG1108 ABC-type Mn2+/Zn2+ transport systems,
permease components"
/codon_start=1
/transl_table=11
/product="iron (chelated) ABC transporter permease
protein"
/protein_id="YP_001290111.1"
/db_xref="GI:148825358"
/db_xref="GeneID:5224718"
/translation="MLDLLLEPFSYDYMLKAMILSTAVGAICAFLSSYLMLKGWSLIG
DALSHSVVPGVAIAYAFALPYALGAFFAGILAALSILWIKSISKLKEDAVIGFIFSTF
FALGLLIISLNPTAVDVQSIILGNILGIADEDIYQVAIIIGVCLVLLLLFWKDLLLIF
FDETQAITVGLSPLFYKILFFTLLSACVVAALQTVGAILVIAMVVTPGATAYLLTDKF
KTLSIIAIILGAVTSFVGVYISYYLDGATGGVIVTLQTLLFLVAFLFSPKYGLLTRNK
KAVENV"
misc_feature 228364..229113
/locus_tag="CGSHiEE_01210"
/note="Transmembrane subunit (TM), of Periplasmic Binding
Protein (PBP)-dependent ATP-Binding Cassette (ABC)
transporters involved in the uptake of siderophores, heme,
vitamin B12, or the divalent cations Mg2+ and Zn2+.
PBP-dependent ABC transporters consist of...; Region:
TM_ABC_iron-siderophores_like; cd06550"
/db_xref="CDD:119348"
misc_feature order(228418..228420,228430..228438,228772..228777,
228781..228789,228793..228798,228802..228819,
228823..228831,228955..228957,228976..228978)
/locus_tag="CGSHiEE_01210"
/note="ABC-ATPase subunit interface; other site"
/db_xref="CDD:119348"
misc_feature order(228433..228435,228439..228441,228454..228456,
228595..228597,228601..228606,228613..228618,
228625..228630,228637..228639,228646..228651,
228655..228657,228682..228687,228694..228696,
228922..228924,229069..229071,229078..229083,
229090..229092,229099..229104,229111..229113)
/locus_tag="CGSHiEE_01210"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:119348"
misc_feature order(228655..228657,228724..228726,228898..228900,
228910..228912,229045..229047,229060..229062)
/locus_tag="CGSHiEE_01210"
/note="putative PBP binding regions; other site"
/db_xref="CDD:119348"
gene 229166..229981
/locus_tag="CGSHiEE_01215"
/db_xref="GeneID:5224719"
CDS 229166..229981
/locus_tag="CGSHiEE_01215"
/note="COG1108 ABC-type Mn2+/Zn2+ transport systems,
permease components"
/codon_start=1
/transl_table=11
/product="iron (chelated) ABC transporter permease
protein"
/protein_id="YP_001290112.1"
/db_xref="GI:148825359"
/db_xref="GeneID:5224719"
/translation="MFDWLLEPLQFEFMQNALLTALIVSIICALLSCYLVLKGWSLMG
DAISHAVLPGIVLAYLAGIPLAIGAFFSGIFCSLGVGYLKENSRIKEDTAMGIVFSGM
FAIGLVMFTKIQTEQHLTHILFGNVLGVSHQELIQSAVISAIIFCLIVFKRKDFLLYC
FDPSHARVAGLSPKILHYGLLILLALTIVSTMQVVGVILVVAMLIAPGITALTLTKSF
DKMLWVAIASSIASSLIGVILSYHFDASTGACIILLQAAFFVIALAYSKIRIR"
misc_feature 229205..229954
/locus_tag="CGSHiEE_01215"
/note="Transmembrane subunit (TM), of Periplasmic Binding
Protein (PBP)-dependent ATP-Binding Cassette (ABC)
transporters involved in the uptake of siderophores, heme,
vitamin B12, or the divalent cations Mg2+ and Zn2+.
PBP-dependent ABC transporters consist of...; Region:
TM_ABC_iron-siderophores_like; cd06550"
/db_xref="CDD:119348"
misc_feature order(229259..229261,229271..229279,229613..229618,
229622..229630,229634..229639,229643..229660,
229664..229672,229796..229798,229817..229819)
/locus_tag="CGSHiEE_01215"
/note="ABC-ATPase subunit interface; other site"
/db_xref="CDD:119348"
misc_feature order(229274..229276,229280..229282,229295..229297,
229436..229438,229442..229447,229454..229459,
229466..229471,229478..229480,229487..229492,
229496..229498,229523..229528,229535..229537,
229763..229765,229910..229912,229919..229924,
229931..229933,229940..229945,229952..229954)
/locus_tag="CGSHiEE_01215"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:119348"
misc_feature order(229496..229498,229565..229567,229739..229741,
229751..229753,229886..229888,229901..229903)
/locus_tag="CGSHiEE_01215"
/note="putative PBP binding regions; other site"
/db_xref="CDD:119348"
gene complement(230081..230728)
/locus_tag="CGSHiEE_01220"
/db_xref="GeneID:5224720"
CDS complement(230081..230728)
/locus_tag="CGSHiEE_01220"
/note="COG0819 Putative transcription activator"
/codon_start=1
/transl_table=11
/product="transcriptional activator"
/protein_id="YP_001290113.1"
/db_xref="GI:148825360"
/db_xref="GeneID:5224720"
/translation="MIEQLIQQAQPYWQQYIEHEFVQQLAKGTLPKACFQHYLKQDYL
YLFHYSRAFALGVFKAKNFAEMETPRKTLEILCQEIQLHLNYCREWGISEQEIFATQE
SAACIAYTRYLLDCGMTGSLAELYAAVTPCALGYAQVARYITQHYPRLPNNPYQTWID
TYASEEFQQAAQETVDFLTALCNPLNPSQLAEIQQIFTTATRMEIAFWQMGLDLA"
misc_feature complement(230087..230728)
/locus_tag="CGSHiEE_01220"
/note="Putative transcription activator [Transcription];
Region: TenA; COG0819"
/db_xref="CDD:31161"
gene complement(230738..231682)
/locus_tag="CGSHiEE_01225"
/db_xref="GeneID:5224721"
CDS complement(230738..231682)
/locus_tag="CGSHiEE_01225"
/note="COG0715 ABC-type nitrate/sulfonate/bicarbonate
transport systems, periplasmic components"
/codon_start=1
/transl_table=11
/product="thiamine biosynthesis protein"
/protein_id="YP_001290114.1"
/db_xref="GI:148825361"
/db_xref="GeneID:5224721"
/translation="MKIIIRYFSFVIGLMLTLPSFAKEKISVMLDWYVNPDHAAIIVA
QQKGFFEKNNLEVEIIEPADPALPPKLAAAEKVDLAVSYQPQLYQQVAEGLPLVRVGS
LISNPLNSVVVLKKSNLKSLADLKGKKVGYSVSGFEDGLLDTMLHSIGLSNKDVELVN
VNWSLSPSLLTGQVDAVIGAFRNFELNQLALEKQEGIAFFPEQYGVPAYDELILVANK
NGVTDKKTSAFLTALEQATSYLQAHPNEAWQAFVSYKPNELNTPLNQLAWKDTLPLLA
NKPRQLDAKRYQQMAEFMQQKGLIPKALALKEYAVEIE"
misc_feature complement(<231149..231619)
/locus_tag="CGSHiEE_01225"
/note="NMT1-like family; Region: NMT1_2; cl15260"
/db_xref="CDD:212369"
misc_feature complement(230942..231580)
/locus_tag="CGSHiEE_01225"
/note="NMT1/THI5 like; Region: NMT1; pfam09084"
/db_xref="CDD:192206"
gene complement(231704..232441)
/locus_tag="CGSHiEE_01230"
/db_xref="GeneID:5225527"
CDS complement(231704..232441)
/locus_tag="CGSHiEE_01230"
/note="COG0600 ABC-type nitrate/sulfonate/bicarbonate
transport system, permease component"
/codon_start=1
/transl_table=11
/product="putative ABC-type nitrate/sulfonate/bicarbonate
transport system, permease"
/protein_id="YP_001290115.1"
/db_xref="GI:148825362"
/db_xref="GeneID:5225527"
/translation="MKIRLLKPLLIVGVLLMIWQMVATLGSFPHYIFPSPQAVGQQLF
THAELLWQHTQVTLLEICLGLLLGFLFGLISALLLSFSRQISAVLLPILVISQAIPVF
AIAPLLVLWFGYGMASKIVMSVLIIYFPVTAACYDGLRNTPQAWLDLAKTFNISPLRL
LLKVRLPAALPAFASGLRIAVSVAPIGAVVGEWVGSSEGLGYLMIHANARMQVDLMFA
ALLILVSISLCLYFSIDWLLHRFIWSV"
misc_feature complement(231716..232393)
/locus_tag="CGSHiEE_01230"
/note="ABC-type nitrate/sulfonate/bicarbonate transport
system, permease component [Inorganic ion transport and
metabolism]; Region: TauC; COG0600"
/db_xref="CDD:30945"
misc_feature complement(231758..232195)
/locus_tag="CGSHiEE_01230"
/note="Transmembrane subunit (TM) found in Periplasmic
Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
transporters which generally bind type 2 PBPs. These types
of transporters consist of a PBP, two TMs, and two
cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
cd06261"
/db_xref="CDD:119394"
misc_feature complement(order(231761..231766,231773..231778,
231782..231787,231794..231799,231827..231832,
231863..231868,231875..231886,231905..231907,
231914..231919,231959..231961,232010..232012,
232019..232024,232034..232036,232040..232045,
232052..232054,232058..232060,232064..232069,
232115..232117,232121..232126,232133..232162,
232166..232177))
/locus_tag="CGSHiEE_01230"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:119394"
misc_feature complement(order(231869..231886,232115..232159))
/locus_tag="CGSHiEE_01230"
/note="conserved gate region; other site"
/db_xref="CDD:119394"
misc_feature complement(order(231797..231799,231827..231829,
231836..231838,231866..231868,232082..232084,
232115..232117))
/locus_tag="CGSHiEE_01230"
/note="putative PBP binding loops; other site"
/db_xref="CDD:119394"
misc_feature complement(order(231938..231940,231950..231955,
231971..232009))
/locus_tag="CGSHiEE_01230"
/note="ABC-ATPase subunit interface; other site"
/db_xref="CDD:119394"
gene complement(232438..233160)
/locus_tag="CGSHiEE_01235"
/db_xref="GeneID:5225528"
CDS complement(232438..233160)
/locus_tag="CGSHiEE_01235"
/codon_start=1
/transl_table=11
/product="putative ABC-type nitrate/sulfonate/bicarbonate
transport system, ATPase"
/protein_id="YP_001290116.1"
/db_xref="GI:148825363"
/db_xref="GeneID:5225528"
/translation="MVRIQDLSLAFNEQTLFEHLNLTLLPNEWVSLLGSSGVGKSTLL
RLLAGIETQGVAQGKILFEPKIRIAWLPQKETLYPWLSIVDNVQLQAVLFGRKSVKTT
EKAKMLLEKVGMAAHWHKPCSQLSGGQKQRVALARTLMQEADLILLDGPFSALDAISR
HQLQDLAFELLEDKSVLLVTHDPQEALRLSQRIFVLRSPETHQTALSAVILPEGNAPR
ELHQANLWALQQQLLQELGGEQ"
misc_feature complement(232480..233160)
/locus_tag="CGSHiEE_01235"
/note="ABC-type nitrate/sulfonate/bicarbonate transport
system, ATPase component [Inorganic ion transport and
metabolism]; Region: TauB; COG1116"
/db_xref="CDD:31313"
misc_feature complement(232564..233157)
/locus_tag="CGSHiEE_01235"
/note="P-loop containing Nucleoside Triphosphate
Hydrolases; Region: P-loop_NTPase; cl09099"
/db_xref="CDD:213113"
misc_feature complement(233038..233061)
/locus_tag="CGSHiEE_01235"
/note="Walker A/P-loop; other site"
/db_xref="CDD:72971"
misc_feature complement(order(232618..232620,232711..232716,
232942..232944,233035..233043,233047..233052))
/locus_tag="CGSHiEE_01235"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:72971"
misc_feature complement(232942..232953)
/locus_tag="CGSHiEE_01235"
/note="Q-loop/lid; other site"
/db_xref="CDD:72971"
misc_feature complement(232759..232788)
/locus_tag="CGSHiEE_01235"
/note="ABC transporter signature motif; other site"
/db_xref="CDD:72971"
misc_feature complement(232711..232728)
/locus_tag="CGSHiEE_01235"
/note="Walker B; other site"
/db_xref="CDD:72971"
misc_feature complement(232693..232704)
/locus_tag="CGSHiEE_01235"
/note="D-loop; other site"
/db_xref="CDD:72971"
misc_feature complement(232612..232632)
/locus_tag="CGSHiEE_01235"
/note="H-loop/switch region; other site"
/db_xref="CDD:72971"
gene 233559..234443
/locus_tag="CGSHiEE_01240"
/db_xref="GeneID:5225529"
CDS 233559..234443
/locus_tag="CGSHiEE_01240"
/note="COG1116 ABC-type nitrate/sulfonate/bicarbonate
transport system, ATPase component"
/codon_start=1
/transl_table=11
/product="CMP-neu5Ac--lipooligosaccharide alpha 2-3
sialyltransferase"
/protein_id="YP_001290117.1"
/db_xref="GI:148825364"
/db_xref="GeneID:5225529"
/translation="MSINQSINQSINQSINQSINQSINQSKSVIIAGNGTSLKSIDYS
LLPKDYDVFRCNQFYFEDHYFLGQENKKVFFNCSVIFEQYYTFMQLIKNNEYKYEYAD
IILSSFVNLGDSELKKIKNVQKLLTQVDIGHYYLNKLPAFDAYLQYNELYENKRITSG
VYMCVVATAMGYKDLYLTGIDFYQEKGNPYAFHHQTENIIKLLPYFSQNKSQSDIHSM
EYDLNALYFLQKHYGVNIYCISPESPLCNYFPLSPLNNPITFILEEKKNYTQDILIPP
KFVYKKLVYIPNQEFTKI"
misc_feature 233637..234440
/locus_tag="CGSHiEE_01240"
/note="Alpha-2,3-sialyltransferase (CST-I); Region: CST-I;
pfam06002"
/db_xref="CDD:147907"
gene 234693..235709
/locus_tag="CGSHiEE_01245"
/db_xref="GeneID:5225530"
CDS 234693..235709
/locus_tag="CGSHiEE_01245"
/note="COG1087 UDP-glucose 4-epimerase"
/codon_start=1
/transl_table=11
/product="UDP-glucose 4-epimerase"
/protein_id="YP_001290118.1"
/db_xref="GI:148825365"
/db_xref="GeneID:5225530"
/translation="MAILVTGGAGYIGSHTVVELLNVGKKVVVLDNLCNSSPKSLERV
KQITGKEAKFYEGDILDRALLQKIFAENEINSVIHFAGLKAVGESVQKPTEYYMNNVA
GTLVLIQEMKRAGVWNFVFSSSATVYGDPKIIPITEDCEVGGTTNPYGTSKYMVEQIL
RDTAKAEPKFSMTILRYFNPVGAHESGLIGEDPNGIPNNLLPYISQVAIGKLAQLSVF
GSDYDTHDGTGVRDYIHVVDLAVGHLKALQRHENDAGLHIYNLGTGHGYSVLDMVKAF
EKANNITIAYKLVERRSGDIATCYSDPSLAAKELGWVAERGLEKMMQDTWNWQKNNPK
GYRD"
misc_feature 234696..235682
/locus_tag="CGSHiEE_01245"
/note="UDP-glucose 4 epimerase, subgroup 1, extended (e)
SDRs; Region: UDP_G4E_1_SDR_e; cd05247"
/db_xref="CDD:187558"
misc_feature 234699..235703
/locus_tag="CGSHiEE_01245"
/note="UDP-glucose 4-epimerase; Region: PLN02240"
/db_xref="CDD:177883"
misc_feature order(234711..234713,234717..234728,234783..234800,
234861..234869,234930..234938,234942..234944,
234987..234989,235056..235064,235137..235139,
235149..235151,235221..235226,235230..235232)
/locus_tag="CGSHiEE_01245"
/note="NAD binding site [chemical binding]; other site"
/db_xref="CDD:187558"
misc_feature order(234960..234962,234966..234974,234981..234986,
234993..234998,235005..235010,235014..235019,
235026..235028,235134..235136,235143..235145,
235155..235157,235164..235169,235173..235181)
/locus_tag="CGSHiEE_01245"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:187558"
misc_feature order(234990..234992,235062..235064,235137..235139,
235149..235151)
/locus_tag="CGSHiEE_01245"
/note="active site"
/db_xref="CDD:187558"
misc_feature order(235062..235070,235137..235139,235221..235229,
235284..235292,235335..235346,235377..235379,
235383..235385,235389..235391,235497..235499,
235566..235568,235575..235577)
/locus_tag="CGSHiEE_01245"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:187558"
gene 235890..237128
/locus_tag="CGSHiEE_01250"
/db_xref="GeneID:5225531"
CDS 235890..237128
/locus_tag="CGSHiEE_01250"
/note="COG0477 Permeases of the major facilitator
superfamily"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290119.1"
/db_xref="GI:148825366"
/db_xref="GeneID:5225531"
/translation="MLICAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVML
PYGLKFLWAPLLDRYFPSFLGRRRSWMLLSQVALLILLYIISLFDPLTQLGTVANIAL
LIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYPWE
TVFLWTALCMLAGIFMTLFLAKEPKIDMQQTNQPFYQAFWIPLQEFFQRKGVIQAIGF
LLFLFLYKFGDSFATTLQTKFIYDMGFSKEDIAIVVKSTALWSSILSGLAGGMIMLKL
GINRALWLFGLVQMVTIGGFIWLSAFGHFDVITSAELWKLGVVIAAEYIGVGLGTAAF
VAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFLAIPG
MLCLFWVAPWKQENNKTRSV"
misc_feature 235911..237080
/locus_tag="CGSHiEE_01250"
/note="muropeptide transporter; Validated; Region: ampG;
PRK11010"
/db_xref="CDD:182898"
misc_feature 235923..236969
/locus_tag="CGSHiEE_01250"
/note="AmpG-like permease; Region: 2A0125; TIGR00901"
/db_xref="CDD:162099"
gene 237211..237855
/gene="adk"
/locus_tag="CGSHiEE_01255"
/db_xref="GeneID:5225532"
CDS 237211..237855
/gene="adk"
/locus_tag="CGSHiEE_01255"
/EC_number="2.7.4.3"
/note="essential enzyme that recycles AMP in active cells;
converts ATP and AMP to two molecules of ADP"
/codon_start=1
/transl_table=11
/product="adenylate kinase"
/protein_id="YP_001290120.1"
/db_xref="GI:148825367"
/db_xref="GeneID:5225532"
/translation="MKIILLGAPGAGKGTQAQFIMNKFGIPQISTGDMFRAAIKAGTE
LGKQAKALMDEGKLVPDELTVALVKDRIAQADCANGFLLDGFPRTIPQADALKDSGVK
IDFVLEFDVPDEVIVERMSGRRVHQTSGRSYHIVYNPPKVEGKDDVTGEDLIIRADDK
PETVLDRLAVYHKQTSPLIDYYQAEAKAGNTQYFRLDGTQKVEEVSQELDKILG"
misc_feature 237211..237852
/gene="adk"
/locus_tag="CGSHiEE_01255"
/note="adenylate kinase; Reviewed; Region: adk; PRK00279"
/db_xref="CDD:178957"
misc_feature 237214..237825
/gene="adk"
/locus_tag="CGSHiEE_01255"
/note="Adenylate kinase (ADK) catalyzes the reversible
phosphoryl transfer from adenosine triphosphates (ATP) to
adenosine monophosphates (AMP) and to yield adenosine
diphosphates (ADP). This enzyme is required for the
biosynthesis of ADP and is essential for...; Region: ADK;
cd01428"
/db_xref="CDD:30189"
misc_feature order(237301..237303,237316..237318,237385..237387,
237460..237465,237469..237474,237484..237486)
/gene="adk"
/locus_tag="CGSHiEE_01255"
/note="AMP-binding site [chemical binding]; other site"
/db_xref="CDD:30189"
misc_feature order(237316..237318,237460..237462,237472..237474,
237577..237579,237709..237711,237721..237723)
/gene="adk"
/locus_tag="CGSHiEE_01255"
/note="ATP-AMP (Ap5A)-binding site [chemical binding];
other site"
/db_xref="CDD:30189"
gene complement(238015..238617)
/locus_tag="CGSHiEE_01260"
/db_xref="GeneID:5225784"
CDS complement(238015..238617)
/locus_tag="CGSHiEE_01260"
/note="COG3005 Nitrate/TMAO reductases, membrane-bound
tetraheme cytochrome c subunit"
/codon_start=1
/transl_table=11
/product="cytochrome C-type protein NapC"
/protein_id="YP_001290121.1"
/db_xref="GI:148825368"
/db_xref="GeneID:5225784"
/translation="MSEKKPNILKRFWQWFRKPSRMAIGTIIILSAIGGILSWVGFNY
GLEKTNTEQFCASCHMQDAYPEYLHSVHYQTRTGVGASCPDCHVPHEFGAKMKRKIIA
AKEVYAHYTGKVDTLEKFNAHRLEMAQNEWARMKANDSKECRNCHNVDRMNFNDQRSV
AARMHQKMKTEGKTCIDCHKGIAHQLPDMSGVESGFKDEK"
misc_feature complement(238048..238596)
/locus_tag="CGSHiEE_01260"
/note="periplasmic nitrate (or nitrite) reductase c-type
cytochrome, NapC/NirT family; Region: napC_nirT;
TIGR02161"
/db_xref="CDD:131216"
gene complement(238632..239075)
/gene="adk"
/locus_tag="CGSHiEE_01265"
/db_xref="GeneID:5225785"
CDS complement(238632..239075)
/gene="adk"
/locus_tag="CGSHiEE_01265"
/EC_number="2.7.4.3"
/note="COG3043 Nitrate reductase cytochrome c-type
subunit"
/codon_start=1
/transl_table=11
/product="adenylate kinase"
/protein_id="YP_001290122.1"
/db_xref="GI:148825369"
/db_xref="GeneID:5225785"
/translation="MTKQVSKILAGLFTALFAGSLMASDAPAVGKDLTQAAENIPPAF
HNAPRQGELPALNYVNQPPMVPHSVANYQVTKNVNQCLNCHSPENSRLSGATRISPTH
FMDRDGKVGSSSSPRRYFCLQCHVSQANVDPIVPNDFKPMKGYGN"
misc_feature complement(238635..239075)
/gene="adk"
/locus_tag="CGSHiEE_01265"
/note="Nitrate reductase cytochrome c-type subunit [Energy
production and conversion]; Region: NapB; COG3043"
/db_xref="CDD:32857"
gene complement(239081..239944)
/gene="napH"
/locus_tag="CGSHiEE_01270"
/db_xref="GeneID:5225786"
CDS complement(239081..239944)
/gene="napH"
/locus_tag="CGSHiEE_01270"
/note="part of NapHG quinol dehydrogenase; couples
electron transfer from ubiquinone-ubiquinol couple via
NapC/B to NapA"
/codon_start=1
/transl_table=11
/product="quinol dehydrogenase membrane component"
/protein_id="YP_001290123.1"
/db_xref="GI:148825370"
/db_xref="GeneID:5225786"
/translation="MANAPKFAGKEAREKWGWWYANRFLFWRRLSQLSILAMFLSGPY
FGVWILKGNYSGSLLLDTIPLSDPLITAESLAARHLPDALTLIGAAIIVLFYAVLGSK
VFCGWVCPLNVVTDCAAWLRRKLGIRQTAKISRGLRYGILVLILLGSCVSGMLLWEWV
NPVAALGRAFVFGFGATGWLLLVIFLFDLLIAEHGWCGHLCPIGAAYGVIGAKSLIRI
KVIDRAKCDNCMDCYNVCPEAQVLRSPLHGKKDESLLVLSKDCISCGRCIDVCAEKVF
KFSTRFDHSGE"
misc_feature complement(239084..239896)
/gene="napH"
/locus_tag="CGSHiEE_01270"
/note="quinol dehydrogenase membrane component;
Provisional; Region: napH; PRK09477"
/db_xref="CDD:181891"
misc_feature complement(239561..239704)
/gene="napH"
/locus_tag="CGSHiEE_01270"
/note="4Fe-4S binding domain; Region: Fer4_5; pfam12801"
/db_xref="CDD:205081"
misc_feature complement(239231..239287)
/gene="napH"
/locus_tag="CGSHiEE_01270"
/note="4Fe-4S binding domain; Region: Fer4_6; pfam12837"
/db_xref="CDD:205098"
gene complement(239944..240777)
/gene="napG"
/locus_tag="CGSHiEE_01275"
/db_xref="GeneID:5225787"
CDS complement(239944..240777)
/gene="napG"
/locus_tag="CGSHiEE_01275"
/note="part of NapHG quinol dehydrogenase; couples
electron transfer from ubiquinone-ubiquinol couple via
NapC/B to NapA; secreted by twin arginine translocation
pathway"
/codon_start=1
/transl_table=11
/product="quinol dehydrogenase periplasmic component"
/protein_id="YP_001290124.1"
/db_xref="GI:148825371"
/db_xref="GeneID:5225787"
/translation="MRLKSKKKMKKPALNPERRKFLKEATRTAGGLAGVGILLGLQQN
QSLAREGVPLRPPFALQDAKAFSAACIRCGQCVQACPYDMLHLASLLSPVEAGTPYFI
ARDKPCEMCPDIPCAKACPSGALDRQATDINESRMGLSVLLDHETCLNYQGLRCDVCY
RVCPLIDKAITLEKQHNPRSDKHALFIPTVHSDACTGCGKCEQACVLEEAAIKILPMD
LAKGMLGKHYRLGWEEKAKAGHSLAPKDMISLPTRTPEGATVMPEPAEPVLAPILGSG
K"
misc_feature complement(239992..240744)
/gene="napG"
/locus_tag="CGSHiEE_01275"
/note="quinol dehydrogenase periplasmic component;
Provisional; Region: napG; PRK09476"
/db_xref="CDD:181890"
gene complement(240838..243321)
/locus_tag="CGSHiEE_01280"
/db_xref="GeneID:5225788"
CDS complement(240838..243321)
/locus_tag="CGSHiEE_01280"
/note="periplasmic; catalytic subunit; with NapBC
catalyzes the reduction of nitrate to nitrite; NapAB
receives electrons from NapC"
/codon_start=1
/transl_table=11
/product="nitrate reductase catalytic subunit"
/protein_id="YP_001290125.1"
/db_xref="GI:148825372"
/db_xref="GeneID:5225788"
/translation="MNLSRRDFMKANAAMAAATAAGLTIPVKNVVAAESEIKWDKGVC
RFCGTGCAVLVGTKDGRVVASQGDPDAEVNRGLNCIKGYFLPKIMYGKDRLTQPLLRM
TNGKFDKNGDFAPVSWDFAFKTMAEKFKEAFKKNGQNAVGMFSSGQSTIWEGYAKNKL
WKAGFRSNNVDPNARHCMASAAVAFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAEMH
PILWSRITDRRISNPDVRVTVLSTYEHRSFELADHGLIFTPQTDLAIMNYIINYLIQN
NAINWDFVNKHTKFKRGETNIGYGLRPEHPLEKDTNRKTAGKMHDSSFEELKQLVSEY
TVEKVSQMSGLDKVQLETLAKLYADPTKKVVSYWTMGFNQHTRGVWVNQLIYNIHLLT
GKISIPGCGPFSLTGQPSACGTAREVGSFPHRLPADLVVTNPKHREIAERIWKLPKGT
VSEKVGLHTIAQDRAMNDGKMNVLWQMCNNNMQAGPNINQERLPGWRKEGNFVIVSDP
YPTVSALSADLILPTAMWVEKEGAYGNAERRTQFWRQQVKAPGEAKSDLWQLMEFAKY
FTTDEMWTEELLAQMPEYRGKTLYEVLFKNGQVDKFPLSELAEGQLNDESEYFGYYVH
KGLFEEYAEFGRGHGHDLAPFDMYHKARGLRWPVVEGKETLWRYREGYDPYVKEGEGV
AFYGYPDKKAIILAVPYEPPAESPDNEYDLWLSTGRVLEHWHTGTMTRRVPELHRAFP
NNLVWMHPLDAQARGLRHGDKIKISSRRGEMISYLDTRGRNKPPRGLVFTTFFDAGQL
ANNLTLDATDPISKETDFKKCAVKVEKAA"
misc_feature complement(240844..243321)
/locus_tag="CGSHiEE_01280"
/note="nitrate reductase catalytic subunit; Provisional;
Region: PRK13532"
/db_xref="CDD:184119"
misc_feature complement(241216..243201)
/locus_tag="CGSHiEE_01280"
/note="Nitrate reductases, NapA (Nitrate-R-NapA), NasA,
and NarB catalyze the reduction of nitrate to nitrite.
Monomeric Nas is located in the cytoplasm and participates
in nitrogen assimilation. Dimeric Nap is located in the
periplasm and is coupled to quinol...; Region:
MopB_Nitrate-R-NapA-like; cd02754"
/db_xref="CDD:29450"
misc_feature complement(order(242662..242664,243085..243087,
243169..243171,243181..243186,243190..243192))
/locus_tag="CGSHiEE_01280"
/note="[4Fe-4S] binding site [ion binding]; other site"
/db_xref="CDD:29450"
misc_feature complement(order(241654..241656,241735..241737,
241747..241755,241795..241806,241870..241872,
241882..241887,242098..242103,242200..242202,
242209..242217,242536..242538,242542..242544,
242593..242601,242671..242676,242683..242694,
242791..242793,242803..242805,242878..242880,
243079..243081))
/locus_tag="CGSHiEE_01280"
/note="molybdopterin cofactor binding site; other site"
/db_xref="CDD:29450"
misc_feature complement(240844..241197)
/locus_tag="CGSHiEE_01280"
/note="Nitrate reductases, NapA (Nitrate-R-NapA), NasA,
and NarB catalyze the reduction of nitrate to nitrite.
Monomeric Nas is located in the cytoplasm and participates
in nitrogen assimilation. Dimeric Nap is located in the
periplasm and is coupled to quinol...; Region:
MopB_CT_Nitrate-R-NapA-like; cd02791"
/db_xref="CDD:30323"
misc_feature complement(order(240871..240876,240922..240924,
240946..240948,241147..241158,241162..241176))
/locus_tag="CGSHiEE_01280"
/note="molybdopterin cofactor binding site; other site"
/db_xref="CDD:30323"
gene complement(243358..243639)
/locus_tag="CGSHiEE_01285"
/db_xref="GeneID:5226114"
CDS complement(243358..243639)
/locus_tag="CGSHiEE_01285"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290126.1"
/db_xref="GI:148825373"
/db_xref="GeneID:5226114"
/translation="MNNTNLISENAGDWHVVGLIVQGNPKKLSAIQTALLAIEHTEIP
TFDEKLGKFVVVMQSHDQHLLLEKMESVKDIDGVINVSLVYHEQDEQNK"
misc_feature complement(243367..243603)
/locus_tag="CGSHiEE_01285"
/note="NapD protein; Region: NapD; pfam03927"
/db_xref="CDD:146517"
gene complement(243632..244162)
/gene="napG"
/locus_tag="CGSHiEE_01290"
/db_xref="GeneID:5226115"
CDS complement(243632..244162)
/gene="napG"
/locus_tag="CGSHiEE_01290"
/note="COG1145 Ferredoxin"
/codon_start=1
/transl_table=11
/product="quinol dehydrogenase periplasmic component"
/protein_id="YP_001290127.1"
/db_xref="GI:148825374"
/db_xref="GeneID:5226115"
/translation="MTVENLPRRQFLRGKFSTLSCLENNQKQSFVGIRLPWSMENSIF
VAQCTRCGDCLSVCETNILVKGDGGFPEVRFDNGECTFCGKCVDACKQPIFYPREQLP
WSHKIDIGVTCLTLHRIECRTCQDNCPANAIRFKLQMGGVAQPLVNFDACNGCGACVQ
GCPVNAITMNDLKQNE"
misc_feature complement(243824..244141)
/gene="napG"
/locus_tag="CGSHiEE_01290"
/note="ferredoxin-type protein NapF; Region: napF;
TIGR00402"
/db_xref="CDD:161860"
misc_feature complement(<243881..>244033)
/gene="napG"
/locus_tag="CGSHiEE_01290"
/note="The HCP family of iron-sulfur proteins includes
hybrid cluster protein (HCP), acetyl-CoA synthase (ACS),
and carbon monoxide dehydrogenase (CODH), all of which
contain [Fe4-S4] metal clusters at their active sites.
These proteins have a conserved...; Region: HCP_like;
cl14655"
/db_xref="CDD:187409"
misc_feature complement(243761..>243952)
/gene="napG"
/locus_tag="CGSHiEE_01290"
/note="RPB11 and RPB3 subunits of RNA polymerase; Region:
RNAP_RPB11_RPB3; cl11409"
/db_xref="CDD:209307"
misc_feature complement(243668..243808)
/gene="napG"
/locus_tag="CGSHiEE_01290"
/note="4Fe-4S dicluster domain; Region: Fer4_7; pfam12838"
/db_xref="CDD:205099"
misc_feature complement(243659..243730)
/gene="napG"
/locus_tag="CGSHiEE_01290"
/note="4Fe-4S binding domain; Region: Fer4; pfam00037"
/db_xref="CDD:200947"
gene complement(244368..244712)
/locus_tag="CGSHiEE_01295"
/db_xref="GeneID:5226116"
CDS complement(244368..244712)
/locus_tag="CGSHiEE_01295"
/note="COG3171 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290128.1"
/db_xref="GI:148825375"
/db_xref="GeneID:5226116"
/translation="MSKSYNQRQRKKLHLAEFQELGFLVNFQFAEGTAIETVDEIVDR
FINEVIQPNGLAYEGSGYLHWEGLVCLEKIGKCDESHRETVKKWLETSGLQQIEVSEL
FDIWWEYPTKVE"
misc_feature complement(244389..244712)
/locus_tag="CGSHiEE_01295"
/note="hypothetical protein; Provisional; Region:
PRK11702"
/db_xref="CDD:183281"
gene complement(244797..245537)
/gene="trmB"
/locus_tag="CGSHiEE_01300"
/gene_synonym="yggH"
/db_xref="GeneID:5226117"
CDS complement(244797..245537)
/gene="trmB"
/locus_tag="CGSHiEE_01300"
/gene_synonym="yggH"
/EC_number="2.1.1.33"
/note="tRNA (guanine-N(7)-)-methyltransferase; catalyzes
the formation of N(7)-methylguanine at position 46 (m7G46)
in tRNA by transferring the methyl residue from
S-adenosyl-L-methionine"
/codon_start=1
/transl_table=11
/product="tRNA (guanine-N(7)-)-methyltransferase"
/protein_id="YP_001290129.1"
/db_xref="GI:148825376"
/db_xref="GeneID:5226117"
/translation="MTQTFADQKRKTVETAEFTEDGRYKRKVRSFVLRTGRLSEFQKN
MMNDNWGTLGLDYQTEPFDFAKIYGNDNPVVLEIGFGMGKSLVDMAFANPDKNYLGIE
VHTPGVGACIAYAVEKGGTNLRVICHDATEILRDSIADGALGGLQLFFPDPWHKAKHH
KRRIVQPHFVAQVVQKLAGNGFIHMATDWENYAEQMLEVLSANTDLVNTSKNGDYIPR
PDFRPLTKFEARGHRLGHGVWDLYFVKK"
misc_feature complement(244836..245456)
/gene="trmB"
/locus_tag="CGSHiEE_01300"
/gene_synonym="yggH"
/note="tRNA (guanine-N(7)-)-methyltransferase; Reviewed;
Region: trmB; PRK00121"
/db_xref="CDD:178880"
gene 245622..247814
/locus_tag="CGSHiEE_01305"
/db_xref="GeneID:5226118"
CDS 245622..247814
/locus_tag="CGSHiEE_01305"
/note="binding of PriA to forked DNA starts the assembly
of the primosome, also possesses 3'-5' helicase activity"
/codon_start=1
/transl_table=11
/product="primosome assembly protein PriA"
/protein_id="YP_001290130.1"
/db_xref="GI:148825377"
/db_xref="GeneID:5226118"
/translation="MKIVRVVLAVPLPRLFDYLVPDDVSLQIGMRVLVPFGTQKRVAI
VADFPTKSDVPEDKLKAILQPLDLAPLFTPIYWDWLHWAANYYQAGLGDVLFQALPVK
LRNGESAVKNDRTFWRITDAGKNALEQGELKRSKKQAEALQYLSETDLEKGNNNFSSA
IWSALKAKGFIEEITIQTKPLSWQQNLGDNPIVNAENRLTLNKQQALAFSQLRFHSGF
NVWLLDGVTGSGKTEIYLQYIEEILKSGKQVLVLVPEIGLTPQTVHRFKARFNVEIDV
LHSNLTDTQRLYVWDRARSGQSAIVIGTRSALFTQFSNLGAIILDEEHDTSYKQQDSW
RYHARDLATVLAQKLNIAVLMGSATPSLESINNVQNGKYQHLVLSKRAGNSTALRHFV
IDLKNQHIQNGLSKPLLERMKAHLEKGNQVLLFLNRRGFAPVLLCHECGWIAQCPHCE
KPYTYHQHQNVLRCHHCGAQKTIPRQCGDCGSTHLVTTGLGTEQLEETLKTLFPHYSV
ARIDRDSTARKGKLESYLEDIQQGKSQILIGTQMLAKGHHFPNVTLVALVNVDSALFS
LDFRAEERLAQLYIQVAGRAGRADKQGEVVLQTHYPDHPLLTTLLANGYQAFAKETLQ
LRHSMGLPPFTFQALFKAQARHSELAQNCLIQIADFFQSKQITGLQMLGPMPAPFSKK
AGQYRWQLLLQHPSRMTLQKALREYQQAELEKNSQVRLILDVDPQDLS"
misc_feature 245622..247808
/locus_tag="CGSHiEE_01305"
/note="primosome assembly protein PriA; Validated; Region:
PRK05580"
/db_xref="CDD:180144"
misc_feature 246276..246701
/locus_tag="CGSHiEE_01305"
/note="DEAD-like helicases superfamily. A diverse family
of proteins involved in ATP-dependent RNA or DNA
unwinding. This domain contains the ATP-binding region;
Region: DEXDc; cd00046"
/db_xref="CDD:28927"
misc_feature 246303..246317
/locus_tag="CGSHiEE_01305"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:28927"
misc_feature 246582..246593
/locus_tag="CGSHiEE_01305"
/note="putative Mg++ binding site [ion binding]; other
site"
/db_xref="CDD:28927"
misc_feature <247134..247412
/locus_tag="CGSHiEE_01305"
/note="Helicase superfamily c-terminal domain; associated
with DEXDc-, DEAD-, and DEAH-box proteins, yeast
initiation factor 4A, Ski2p, and Hepatitis C virus NS3
helicases; this domain is found in a wide variety of
helicases and helicase related proteins; may...; Region:
HELICc; cd00079"
/db_xref="CDD:28960"
misc_feature order(247134..247139,247239..247247)
/locus_tag="CGSHiEE_01305"
/note="nucleotide binding region [chemical binding]; other
site"
/db_xref="CDD:28960"
misc_feature order(247263..247265,247362..247364,247374..247376,
247383..247385)
/locus_tag="CGSHiEE_01305"
/note="ATP-binding site [chemical binding]; other site"
/db_xref="CDD:28960"
gene complement(247856..248902)
/locus_tag="CGSHiEE_01310"
/db_xref="GeneID:5226119"
CDS complement(247856..248902)
/locus_tag="CGSHiEE_01310"
/note="COG0628 Predicted permease"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290131.1"
/db_xref="GI:148825378"
/db_xref="GeneID:5226119"
/translation="MQNNLNLHRTLLGIAAVIIILAGVKLAAEIVVPFLLSLFIAIIC
SPIIKAMTQRRVPHWLAITLLFVLISLVFFFLVGLINSTAREFTQSIPQYKVLLSQRV
SDLTGLLQRFNLPFTLSRETIQENFDPSIIMNFVSRVLLNFSGVVSNVFVLVLVVIFM
LAEAPTMKHKFAMVISSTPHDAVKEERHIDRVLQGVIGYLGIKSITSLLTGVGVFILL
EACGVQYAILWATLSFLLNYIPNIGSIIAAIPIIVQALLLNGFGVGFGVAVGVIAINM
VVGNIIEPKMMGQRLGLSTLVVFLSLLFWGWLLGTVGMLLSVPLTMALKIALESSPNT
AKYACLLGDVEDFK"
misc_feature complement(247871..248818)
/locus_tag="CGSHiEE_01310"
/note="pheromone autoinducer 2 transporter; Reviewed;
Region: tqsA; cl00465"
/db_xref="CDD:207060"
misc_feature complement(247916..248818)
/locus_tag="CGSHiEE_01310"
/note="Domain of unknown function DUF20; Region: UPF0118;
pfam01594"
/db_xref="CDD:201878"
gene complement(248902..249240)
/locus_tag="CGSHiEE_01315"
/db_xref="GeneID:5225402"
CDS complement(248902..249240)
/locus_tag="CGSHiEE_01315"
/note="COG0347 Nitrogen regulatory protein PII"
/codon_start=1
/transl_table=11
/product="nitrogen regulatory protein P-II"
/protein_id="YP_001290132.1"
/db_xref="GI:148825379"
/db_xref="GeneID:5225402"
/translation="MKKIEAMIKPFKLDDVRESLSDIGISGMTITEVRGFGRQKGHTE
LYRGAEYMVDFLPKVKLEVVVPDELVDQCIEAIVETAQTGKIGDGKIFVYHVERAIRI
RTGEENEDAI"
misc_feature complement(248926..249231)
/locus_tag="CGSHiEE_01315"
/note="Nitrogen regulatory protein P-II; Region: P-II;
pfam00543"
/db_xref="CDD:201295"
misc_feature complement(248926..249231)
/locus_tag="CGSHiEE_01315"
/note="Nitrogen regulatory protein P-II; Region: P-II;
smart00938"
/db_xref="CDD:198006"
gene complement(249242..249835)
/gene="mogA"
/locus_tag="CGSHiEE_01320"
/db_xref="GeneID:5225403"
CDS complement(249242..249835)
/gene="mogA"
/locus_tag="CGSHiEE_01320"
/note="forms a trimer; related to eukaryotic protein
gephyrin; functions during molybdenum cofactor
biosynthesis"
/codon_start=1
/transl_table=11
/product="molybdenum cofactor biosynthesis protein MogA"
/protein_id="YP_001290133.1"
/db_xref="GI:148825380"
/db_xref="GeneID:5225403"
/translation="MTALLKIGLVSVSDRASAGVYQDQGIPELQAWLEQALVDPFHLE
TRLIPDEQPIIEQTLKELVDEQGCHLVLTTGGTGPAKRDVTPDATLAVADREMPGFGE
QMRQVSLHFVPTAILSRQVGVIRKESLILNLPGQPKAIKETLEGVKDKEGNVLVKGIF
SAVPYCLQLINGLYIDTKPEIIESFRPKSARRENLEK"
misc_feature complement(249326..249823)
/gene="mogA"
/locus_tag="CGSHiEE_01320"
/note="MogA_MoaB family. Members of this family are
involved in biosynthesis of the molybdenum cofactor (MoCF)
an essential cofactor of a diverse group of redox enzymes.
MoCF biosynthesis is an evolutionarily conserved pathway
present in eubacteria, archaea; Region: MogA_MoaB;
cd00886"
/db_xref="CDD:58167"
misc_feature complement(order(249410..249412,249419..249421,
249431..249436,249512..249514,249602..249610))
/gene="mogA"
/locus_tag="CGSHiEE_01320"
/note="MPT binding site; other site"
/db_xref="CDD:58167"
misc_feature complement(order(249326..249328,249479..249481,
249488..249490,249518..249523,249530..249532,
249545..249553,249575..249577,249587..249589,
249593..249598,249602..249604))
/gene="mogA"
/locus_tag="CGSHiEE_01320"
/note="trimer interface [polypeptide binding]; other site"
/db_xref="CDD:58167"
gene complement(249918..250274)
/locus_tag="CGSHiEE_01325"
/db_xref="GeneID:5225404"
CDS complement(249918..250274)
/locus_tag="CGSHiEE_01325"
/note="COG0818 Diacylglycerol kinase"
/codon_start=1
/transl_table=11
/product="diacylglycerol kinase"
/protein_id="YP_001290134.1"
/db_xref="GI:148825381"
/db_xref="GeneID:5225404"
/translation="MYKTTGLTHLINSTKYSLQGLKSAFKNETAFRHECFLACILIPL
TFFLGETKIEIILMISSVLLVMALELLNSAVEAVVDRIGTERHELSGRAKDQGSASVF
IALCIVGIVWGGILFF"
misc_feature complement(249924..250274)
/locus_tag="CGSHiEE_01325"
/note="Diacylglycerol kinase [Cell envelope biogenesis,
outer membrane]; Region: DgkA; COG0818"
/db_xref="CDD:31160"
gene complement(250289..252520)
/locus_tag="CGSHiEE_01330"
/db_xref="GeneID:5225405"
CDS complement(250289..252520)
/locus_tag="CGSHiEE_01330"
/note="COG0317 Guanosine polyphosphate
pyrophosphohydrolases/synthetases"
/codon_start=1
/transl_table=11
/product="GTP pyrophosphokinase"
/protein_id="YP_001290135.1"
/db_xref="GI:148825382"
/db_xref="GeneID:5225405"
/translation="MVAVRGSHLLNPQNFVIEQWCTGLKLAEQTEKSLIDAWYYARDL
MNAYPDEMKNATLMLQSGVEMVEILHELNMDAETLLTAMLFPIVANKLTDWESLKEKF
GAKITKLLKGVLEMDNIRQLNASHSANALQVDNVRRMLLAMVDDFRCVIIKLAERITF
LRDAEHRCAEEDKVLAVKECSYIYAPLANRLGIGQLKWELEDYCFRYLHPEQYRAIAK
LLQERRLDREHYIADFVSELSSYLRENIKQVEVYGRPKHIYSIWRKMQKKNLEFSGLY
DVRAVRIIVQKLQDCYTALGIVHTQFKHLPKEFDDYVANPKPNGYQSIHTVVLGKGDK
PIEVQIRTQQMHDDAELGMAAHWKYKEGNTGSMSAYEEKIAWLRKLLAWQDDITDSGE
VLAELRSQVFDDRVYVFTPKGEVVDLPMGSTPLDFAYAIHSEIGHRCIGAKVAGRIVP
FTYQLQMGDQIDIITQKNPNPSRDWLNPNLGFTHTAKSRAKIQAWFKKQDRDKNIPAG
KELLDNELALLNLSIKQVEPYALPRYNLKNLDDLYAGIGSGDIRLNNLIHFLQSKLIK
VTAEEADQEILRHVANKSAVNSQQKSEKNNGYVIVEGVDNLMHHIARCCQPIPGDAIV
GYITMGRGISIHRADCEQFLDLQAAHPERVVESIWGENYASGFHINIRIVAGDRNGLL
RDITTVLANEKISVLGVSSRADTKKQLATIDMEIELHNVESLSKILARLAKLDDVIEA
KRL"
misc_feature complement(250292..252520)
/locus_tag="CGSHiEE_01330"
/note="(p)ppGpp synthetase I/GTP pyrophosphokinase;
Provisional; Region: relA; PRK10872"
/db_xref="CDD:182797"
misc_feature complement(251939..252412)
/locus_tag="CGSHiEE_01330"
/note="HD domain; Region: HD_4; pfam13328"
/db_xref="CDD:205508"
misc_feature complement(251468..251833)
/locus_tag="CGSHiEE_01330"
/note="Nucleotidyltransferase (NT) domain of RelA- and
SpoT-like ppGpp synthetases and hydrolases; Region:
NT_Rel-Spo_like; cd05399"
/db_xref="CDD:143389"
misc_feature complement(order(251471..251476,251498..251500,
251504..251506,251510..251512,251546..251548,
251558..251560,251564..251566,251570..251572,
251585..251587,251591..251593,251675..251677,
251687..251692,251753..251755,251759..251761))
/locus_tag="CGSHiEE_01330"
/note="synthetase active site [active]"
/db_xref="CDD:143389"
misc_feature complement(order(251474..251476,251504..251506,
251510..251512,251546..251548,251558..251560,
251564..251566,251570..251572,251585..251587,
251591..251593,251759..251761))
/locus_tag="CGSHiEE_01330"
/note="NTP binding site [chemical binding]; other site"
/db_xref="CDD:143389"
misc_feature complement(order(251510..251512,251690..251692))
/locus_tag="CGSHiEE_01330"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:143389"
misc_feature complement(251126..251305)
/locus_tag="CGSHiEE_01330"
/note="TGS_RelA_SpoT: The RelA (SpoT) protein, also
referred to as ppGpp hydrolase/synthetase, is a
ribosome-associated protein that is activated during amino
acid starvation and thought to mediate the stringent
response. RelA contains a TGS domain, named after...;
Region: TGS_RelA_SpoT; cd01668"
/db_xref="CDD:133438"
misc_feature complement(250295..250510)
/locus_tag="CGSHiEE_01330"
/note="ACT domain found C-terminal of the RelA/SpoT
domains; Region: ACT_RelA-SpoT; cd04876"
/db_xref="CDD:153148"
gene complement(252740..253321)
/locus_tag="CGSHiEE_01335"
/db_xref="GeneID:5225406"
CDS complement(252740..253321)
/locus_tag="CGSHiEE_01335"
/note="COG1403 Restriction endonuclease"
/codon_start=1
/transl_table=11
/product="HNH endonuclease"
/protein_id="YP_001290136.1"
/db_xref="GI:148825383"
/db_xref="GeneID:5225406"
/translation="MRIHGENEISRSIGVNQENDYKKYVPQLREDFKHICGYCGKPEE
VTTKGFEPDHFVPDRIDSSRKLDYSNLVYSCFTCNRKKLGKWPTKNKDKPNDGNVGFV
DPALKEYDLHLGRDKDGNIEFYTNVGEYMYKNAFRFDIRPMKEIWKISQLINAKENLL
KIKDKLTSEELIKYLELDKAIEELKKILFEKKE"
misc_feature complement(253076..253228)
/locus_tag="CGSHiEE_01335"
/note="HNH nucleases; HNH endonuclease signature which is
found in viral, prokaryotic, and eukaryotic proteins. The
alignment includes members of the large group of homing
endonucleases, yeast intron 1 protein, MutS, as well as
bacterial colicins, pyocins, and...; Region: HNHc;
cd00085"
/db_xref="CDD:28969"
misc_feature complement(order(253085..253087,253094..253099,
253109..253114,253151..253153,253157..253165,
253169..253171))
/locus_tag="CGSHiEE_01335"
/note="active site"
/db_xref="CDD:28969"
gene complement(253327..253944)
/locus_tag="CGSHiEE_01340"
/db_xref="GeneID:5225407"
CDS complement(253327..253944)
/locus_tag="CGSHiEE_01340"
/note="COG0784 FOG: CheY-like receiver"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290137.1"
/db_xref="GI:148825384"
/db_xref="GeneID:5225407"
/translation="MYRIGFIDDDQDSYEDYRVRLARKDIELLYPNGITEMPEMIEWL
LSNGIKCFIIDYKLNNKFKFLGTELIAYINAKVPDLPCLILTNYPEESIRENLVIINL
IEDRNVLAADDIEEFVKKIKQAVDVFENRLRKYHIDYEELLKAKKNGSISAIEEEQFI
DLYKLLRAYGEVDDLPIQLLSSEVNQKIDEILGRVNILVEKVENR"
gene complement(253960..256245)
/locus_tag="CGSHiEE_01345"
/db_xref="GeneID:5225161"
CDS complement(253960..256245)
/locus_tag="CGSHiEE_01345"
/note="COG0326 Molecular chaperone, HSP90 family"
/codon_start=1
/transl_table=11
/product="histidine kinase"
/protein_id="YP_001290138.1"
/db_xref="GI:148825385"
/db_xref="GeneID:5225161"
/translation="MAKISFNVDAYTARLIGRENVSKLNGAIIELVKNTYDADATICV
LYYEKTTNSLYIADNGCGMTKDVIIKHWMTIGRSTKKKQFISKSGRVQTGAKGIGRFA
LDRISDTCEMFTVSAEGKLIWKVDWEDFSKSDNITDVTADLYEPTLSIDGFLDEVINY
EVKNIILNNLKNTGTIFRLTSLRDSWNDNVIKKIKDDLITLIPYEMKNEFQVYFFDEK
SSAEDAEVLNITNAFSYDYKIRFNVLSDGDTHIEIHRNEFDFGDRFDEIITQAEFTSE
DEQYFKGKCICIETNFAQMLPKRGEQLKNTIGEFSGVLYFEKVTYSKTDAERYFYKTS
NNRNIKSDIFGGIKIYRDGFRVRPYGEPKTSDYDWLLIAGRKNKSPAAPSHQTGAWRV
NTDQIIGSIFISRMNITLPDQSNREGIVETKEFILLKEFLINVIQEFEKDRQYVFRKL
DARYDKIMEAARIQDEINKKAEEAKAAREEKRFLSDSKDFNQELQLSKISINPEEAKI
VLDHKDTVIRNLEDENRLLRTLATTGIVTNTYVHEIKDITHKLSIKIVMAKEALELDS
DLQAGLKYVTEANVMRESLNSWFKVTIGSVTRDKRTMKKTDLNLLISQTVKLWKETLK
NVSIDLEFQGSEIQLKCFPYDIESIFSNLIANSVSSFESYFSDNKSIKIVVSDLEKEI
IIKYSDSGRGLSLAYKNNPRKILEPMESDRRNEMGETIGTGMGMWIINRTVADYNGSI
DLSDNSKYTSGFYATIKLIKK"
misc_feature complement(255787..256179)
/locus_tag="CGSHiEE_01345"
/note="Histidine kinase-, DNA gyrase B-, and HSP90-like
ATPase; Region: HATPase_c_3; pfam13589"
/db_xref="CDD:205767"
misc_feature complement(254125..>254751)
/locus_tag="CGSHiEE_01345"
/note="Signal transduction histidine kinase [Signal
transduction mechanisms]; Region: BaeS; COG0642"
/db_xref="CDD:30987"
misc_feature complement(256260..257688)
/note="potential frameshift: common BLAST hit:
gi|24378571|ref|NP_720526.1| putative site-specific
DNA-methyltransferase"
misc_feature complement(257742..259333)
/note="potential frameshift: common BLAST hit:
gi|68248938|ref|YP_248050.1| 23S rRNA
(uracil-5-)-methyltransferase [Haemophilus influenzae]"
gene complement(259333..260043)
/gene="recO"
/locus_tag="CGSHiEE_01370"
/db_xref="GeneID:5225162"
CDS complement(259333..260043)
/gene="recO"
/locus_tag="CGSHiEE_01370"
/note="involved in DNA repair and RecFOR pathway
recombination; RecFOR proteins displace ssDNA-binding
protein and facilitate the production of RecA-coated
ssDNA"
/codon_start=1
/transl_table=11
/product="DNA repair protein RecO"
/protein_id="YP_001290139.1"
/db_xref="GI:148825386"
/db_xref="GeneID:5225162"
/translation="MQSELQRGFVLHRRPYSETSLLVDLFTEESGRLTVIAKGARAKR
SSWKSVLQPFTPLLLRWTGKSTLKTLTKAEPAAITLPLQQITLYSGFYVNELLTRVIE
SETPNPALFQHYLKCLTGLATETNVEPTLRLFEFQLLQILGYGVDFLHCAGSGEPVDF
SMTYRYREEKGFVASLVKDNLTFYGRDLLAFEALDFSDDAVRQAAKRFTRIALKPYLG
DKPLKSRELFTQNILLLK"
misc_feature complement(259354..260043)
/gene="recO"
/locus_tag="CGSHiEE_01370"
/note="DNA repair protein RecO; Reviewed; Region: recO;
PRK00085"
/db_xref="CDD:178852"
misc_feature complement(259816..260043)
/gene="recO"
/locus_tag="CGSHiEE_01370"
/note="Recombination protein O N terminal; Region: RecO_N;
pfam11967"
/db_xref="CDD:204797"
misc_feature complement(259366..259788)
/gene="recO"
/locus_tag="CGSHiEE_01370"
/note="Recombination protein O C terminal; Region: RecO_C;
pfam02565"
/db_xref="CDD:202286"
gene complement(260046..260450)
/locus_tag="CGSHiEE_01375"
/db_xref="GeneID:5225163"
CDS complement(260046..260450)
/locus_tag="CGSHiEE_01375"
/note="COG1381 Recombinational DNA repair protein (RecF
pathway)"
/codon_start=1
/transl_table=11
/product="opacity associated protein OapB"
/protein_id="YP_001290140.1"
/db_xref="GI:148825387"
/db_xref="GeneID:5225163"
/translation="MLKKTSLIFTALLLVGCAQNANVTTPQAQKMQVEKVDKALQKGE
ADRYLCQDDKVVRVVHATHKKYKKNLHYVTVTFQGVSEKLTLMISERGKNYANIRWMW
QERDDFSTLKTNLGEILATQCVSQTSERLSGQ"
gene complement(260510..261796)
/locus_tag="CGSHiEE_01380"
/db_xref="GeneID:5225072"
CDS complement(260510..261796)
/locus_tag="CGSHiEE_01380"
/note="COG0532 Translation initiation factor 2 (IF-2;
GTPase)"
/codon_start=1
/transl_table=11
/product="opacity associated protein"
/protein_id="YP_001290141.1"
/db_xref="GI:148825388"
/db_xref="GeneID:5225072"
/translation="MDKNEQSSQNELDLGLSQEPITPKKTIQPSSSILGKTKGLFAKK
NHVQTNFQQRKEPTFGNSSTQENDPLIPSENLKTVQKPVLQTSSTEENISAVDEEISA
ENNADEPVEKAEKPILAQPEKWKILQVLPAKHRRLFMAIFVLVILLIIFFALKPSSDT
VESFTQSNSNEIPVQFQSLDQSQPVETTILDNPPAQNQMAAEQANQPESAPKAEEAAN
NTTVQNPLVENAPMQQNVVQSPSQMPNEMAAASVAPMQPTQAEQPKATAPVQPMKKAV
EPQVVHKDTAKKEVKVAEKAQAPSKATEQNVAKTAGNAPIVEAKPVQAKKEKKVQIVD
AKPVSKSTASRLSAKTLTVPKGVSLMQVFRDNQLNISDVNAMSKAAGAGNVLSSFKSG
DKVTVSVNNQGRVNEMRLSNGARFVRQSDGSYQYKK"
misc_feature complement(260513..261250)
/locus_tag="CGSHiEE_01380"
/note="Cell envelope opacity-associated protein A [Cell
envelope biogenesis, outer membrane]; Region: OapA;
COG3061"
/db_xref="CDD:32875"
misc_feature complement(260513..260758)
/locus_tag="CGSHiEE_01380"
/note="Opacity-associated protein A LysM-like domain;
Region: OapA; pfam04225"
/db_xref="CDD:113015"
gene complement(261904..262920)
/gene="recO"
/locus_tag="CGSHiEE_01385"
/db_xref="GeneID:5225073"
CDS complement(261904..262920)
/gene="recO"
/locus_tag="CGSHiEE_01385"
/note="COG1509 Lysine 2,3-aminomutase"
/codon_start=1
/transl_table=11
/product="DNA repair protein RecO"
/protein_id="YP_001290142.1"
/db_xref="GI:148825389"
/db_xref="GeneID:5225073"
/translation="MRILTQEPVIREEQNWLTILKNAISDPKLLLKALNLPEDDFEQS
IAARKLFSLRVPQPFIDKIEKGNPQDPLFLQVMCSDLEFVQAEGFSTDPLEEKNANAV
PNILHKYQNRLLFMAKGGCAVNCRYCFRRHFPYDENPGNKKSWQLALDYIAVHPEIEE
VIFSGGDPLMAKDHELAWLIKHLENIPHLQRLRIHTRLPVVIPQRITDEFCTLLAESR
LQTVMVTHINHPNEIDQIFAHAMQKLNAVNVTLLNQSVLLKGVNDDAQILKILSDKLF
QTGILPYYLHLLDKVQGASHFLISDIEAMQIYKTLQSLTSGYLVPKLAREIAGEPNKT
LYAE"
misc_feature complement(261907..262920)
/gene="recO"
/locus_tag="CGSHiEE_01385"
/note="Lysine 2,3-aminomutase [Amino acid transport and
metabolism]; Region: KamA; COG1509"
/db_xref="CDD:31698"
misc_feature complement(261988..262566)
/gene="recO"
/locus_tag="CGSHiEE_01385"
/note="Radical SAM superfamily. Enzymes of this family
generate radicals by combining a 4Fe-4S cluster and
S-adenosylmethionine (SAM) in close proximity. They are
characterized by a conserved CxxxCxxC motif, which
coordinates the conserved iron-sulfur cluster; Region:
Radical_SAM; cd01335"
/db_xref="CDD:100105"
misc_feature complement(order(262057..262062,262153..262155,
262243..262245,262330..262338,262420..262425,
262429..262431,262534..262542,262546..262548,
262552..262554,262558..262560))
/gene="recO"
/locus_tag="CGSHiEE_01385"
/note="FeS/SAM binding site; other site"
/db_xref="CDD:100105"
gene 262958..263524
/locus_tag="CGSHiEE_01390"
/db_xref="GeneID:5225074"
CDS 262958..263524
/locus_tag="CGSHiEE_01390"
/note="Involved in peptide bond synthesis; alters the
affinity of the ribosome for aminoacyl-tRNA"
/codon_start=1
/transl_table=11
/product="elongation factor P"
/protein_id="YP_001290143.1"
/db_xref="GI:148825390"
/db_xref="GeneID:5225074"
/translation="MATYTTSDFKPGLKFMQDGEPCVIVENEFVKPGKGQAFTRTRIR
KLISGKVLDVNFKSGTSVEAADVMDLNLTYSYKDDAFWYFMHPETFEQYSADAKAVGD
AEKWLLDQADCIVTLWNGAPITVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
VVKVPLFVQIGEVIRVDTRSGEYVSRVK"
misc_feature 262964..263521
/locus_tag="CGSHiEE_01390"
/note="elongation factor P; Validated; Region: PRK00529"
/db_xref="CDD:179058"
misc_feature 262970..263143
/locus_tag="CGSHiEE_01390"
/note="Elongation factor P (EF-P) KOW-like domain; Region:
EFP_N; pfam08207"
/db_xref="CDD:203876"
misc_feature 263168..263341
/locus_tag="CGSHiEE_01390"
/note="S1_EF-P_repeat_1: Translation elongation factor P
(EF-P), S1-like RNA-binding domain, repeat 1. EF-P
stimulates the peptidyltransferase activity in the
prokaryotic 70S ribosome. EF-P enhances the synthesis of
certain dipeptides with...; Region: S1_EF-P_repeat_1;
cd04470"
/db_xref="CDD:88435"
misc_feature order(263228..263230,263303..263305,263318..263323)
/locus_tag="CGSHiEE_01390"
/note="RNA binding site [nucleotide binding]; other site"
/db_xref="CDD:88435"
misc_feature 263348..263515
/locus_tag="CGSHiEE_01390"
/note="S1_EF-P_repeat_2: Translation elongation factor P
(EF-P), S1-like RNA-binding domain, repeat 1. EF-P
stimulates the peptidyltransferase activity in the
prokaryotic 70S ribosome. EF-P enhances the synthesis of
certain dipeptides with...; Region: S1_EF-P_repeat_2;
cd05794"
/db_xref="CDD:88469"
misc_feature order(263435..263437,263486..263488,263501..263506)
/locus_tag="CGSHiEE_01390"
/note="RNA binding site [nucleotide binding]; other site"
/db_xref="CDD:88469"
gene 263735..263824
/locus_tag="CGSHiEE_t09348"
/db_xref="GeneID:5542117"
tRNA 263735..263824
/locus_tag="CGSHiEE_t09348"
/product="tRNA-Ser"
/db_xref="GeneID:5542117"
gene complement(263876..264460)
/locus_tag="CGSHiEE_01395"
/db_xref="GeneID:5225075"
CDS complement(263876..264460)
/locus_tag="CGSHiEE_01395"
/note="COG3923 Primosomal replication protein N''"
/codon_start=1
/transl_table=11
/product="primosomal replication protein N"
/protein_id="YP_001290144.1"
/db_xref="GI:148825391"
/db_xref="GeneID:5225075"
/translation="MTVQQLIQRLDQKVQQLYQTNLPQEEKIFAKFDRTLFSENGQTV
AFYLKEINQTLDKIKSLQSENPDHYIFITKRLLAQCTALSEALTHKNKPFIINTNPIP
QPQKKSQHNIHKLPPRERLEKYYEAREQLNNLYRQHKDLAQAEKNNDEKIRYAQLAEV
YKKRQQKCQEAIDLLEEYLVFKEELENRENTENR"
misc_feature complement(263915..264460)
/locus_tag="CGSHiEE_01395"
/note="Primosomal replication protein N'' [DNA
replication, recombination, and repair]; Region: PriC;
COG3923"
/db_xref="CDD:33708"
misc_feature complement(264492..265845)
/note="potential frameshift: common BLAST hit:
gi|113461157|ref|YP_719225.1| possible permease
[Haemophilus somnus 129PT]"
gene complement(266162..266851)
/locus_tag="CGSHiEE_01410"
/db_xref="GeneID:5225076"
CDS complement(266162..266851)
/locus_tag="CGSHiEE_01410"
/note="Responsible for the end-turnover of tRNA:
specifically removes the terminal AMP residue from
uncharged tRNA (tRNA-C-C-A)"
/codon_start=1
/transl_table=11
/product="ribonuclease T"
/protein_id="YP_001290145.1"
/db_xref="GI:148825392"
/db_xref="GeneID:5225076"
/translation="MSDSQEIPYHNQLKNRFRGYFPVIIDVETAGFDAKKDALLELAA
ITLKMDENGYLHPDQKCHFHIEPFEGANINPESLKFNGIDIHNPLRGAVSELDAITGL
FQMIRRGQKDADCQRSIIVAHNAAFDQSFVMAAAERTGVKRNPFHPFGMFDTASLAGL
MFGQTVLVKACLAAKIPFDGKQAHSALYDTERTAELFCYMVNHLKDLGGFPHISQIDE
TENTAENQTAL"
misc_feature complement(266216..266851)
/locus_tag="CGSHiEE_01410"
/note="ribonuclease T; Provisional; Region: PRK05168"
/db_xref="CDD:179951"
misc_feature complement(266213..266815)
/locus_tag="CGSHiEE_01410"
/note="DNA polymerase III, epsilon subunit and related
3'-5' exonucleases [DNA replication, recombination, and
repair]; Region: DnaQ; COG0847"
/db_xref="CDD:31188"
misc_feature complement(order(266285..266287,266468..266476,
266480..266485,266765..266776))
/locus_tag="CGSHiEE_01410"
/note="active site"
/db_xref="CDD:176647"
misc_feature complement(order(266285..266287,266468..266470,
266768..266770,266774..266776))
/locus_tag="CGSHiEE_01410"
/note="catalytic site [active]"
/db_xref="CDD:176647"
misc_feature complement(order(266285..266287,266471..266476,
266480..266485,266765..266773))
/locus_tag="CGSHiEE_01410"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:176647"
gene complement(266926..267333)
/locus_tag="CGSHiEE_01415"
/db_xref="GeneID:5225067"
CDS complement(266926..267333)
/locus_tag="CGSHiEE_01415"
/note="COG0346 Lactoylglutathione lyase and related
lyases"
/codon_start=1
/transl_table=11
/product="lactoylglutathione lyase"
/protein_id="YP_001290146.1"
/db_xref="GI:148825393"
/db_xref="GeneID:5225067"
/translation="MQILHTMLRVGDLDRSIKFYQDVLGMRLLRTSENPEYKYTLAFL
GYEDGESAAEIELTYNWGVDKYEHGTAYGHIAIGVDDIYATCEAVRASGGNVTREAGP
VKGGSTVIAFVEDPDGYKIEFIENKSTKSGLGD"
misc_feature complement(266965..267330)
/locus_tag="CGSHiEE_01415"
/note="Glyoxalase/Bleomycin resistance protein/Dioxygenase
superfamily; Region: Glyoxalase; pfam00903"
/db_xref="CDD:201499"
misc_feature complement(266962..267324)
/locus_tag="CGSHiEE_01415"
/note="Glyoxalase I catalyzes the isomerization of the
hemithioacetal, formed by a 2-oxoaldehyde and glutathione,
to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233"
/db_xref="CDD:176659"
misc_feature complement(order(266968..266970,266977..266979,
267070..267072,267094..267123,267151..267156,
267166..267171,267175..267177,267196..267198,
267208..267210,267238..267243,267250..267252,
267259..267261,267268..267273,267280..267285,
267292..267297,267307..267309,267313..267324))
/locus_tag="CGSHiEE_01415"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:176659"
misc_feature complement(order(266968..266970,266974..266976,
266998..267000,267004..267006,267040..267042,
267112..267114,267154..267156,267160..267162,
267166..267168,267211..267213,267217..267219,
267232..267234,267307..267309,267319..267321))
/locus_tag="CGSHiEE_01415"
/note="active site"
/db_xref="CDD:176659"
misc_feature complement(order(266968..266970,267112..267114,
267166..267168,267319..267321))
/locus_tag="CGSHiEE_01415"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:176659"
misc_feature complement(order(266974..266976,266998..267000,
267004..267006,267040..267042,267154..267156,
267160..267162,267211..267213,267217..267219,
267232..267234,267307..267309))
/locus_tag="CGSHiEE_01415"
/note="glutathione binding site [chemical binding]; other
site"
/db_xref="CDD:176659"
gene complement(267400..267804)
/locus_tag="CGSHiEE_01420"
/db_xref="GeneID:5225069"
CDS complement(267400..267804)
/locus_tag="CGSHiEE_01420"
/note="COG1487 Predicted nucleic acid-binding protein,
contains PIN domain"
/codon_start=1
/transl_table=11
/product="nucleic acid-binding protein"
/protein_id="YP_001290147.1"
/db_xref="GI:148825394"
/db_xref="GeneID:5225069"
/translation="MIYMLDTNIIIYLMKNRPKIVAERVSQLLPNDRLVISFITYAEL
IKGAFGSQNYEQSIRAIELLTERVNVLYPNEQICLHYGKWANTLKKQGRPIGNNDLWI
ACHALSLNAVLITHNVKEFQRITDLQWQDWTK"
misc_feature complement(267412..267795)
/locus_tag="CGSHiEE_01420"
/note="PIN domain of ribonucleases (toxins), VapC and
FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus
horikoshii protein PH0500, and other similar bacterial and
archaeal homologs; Region: PIN_VapC-FitB; cd09881"
/db_xref="CDD:189051"
misc_feature complement(order(267442..267444,267499..267504,
267508..267513,267517..267519,267538..267540,
267547..267552,267559..267564,267568..267570,
267583..267591,267595..267597,267619..267621,
267628..267630,267664..267672,267676..267684,
267688..267693,267703..267705,267727..267729,
267736..267738,267760..267768,267772..267777,
267784..267792))
/locus_tag="CGSHiEE_01420"
/note="oligomeric interface; other site"
/db_xref="CDD:189051"
misc_feature complement(order(267454..267456,267508..267510,
267676..267678,267787..267789))
/locus_tag="CGSHiEE_01420"
/note="putative active site [active]"
/db_xref="CDD:189051"
misc_feature complement(order(267505..267507,267511..267516,
267547..267552,267556..267564,267568..267573,
267586..267588,267613..267615,267622..267627,
267667..267672,267676..267681,267688..267693))
/locus_tag="CGSHiEE_01420"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:189051"
gene complement(267801..268037)
/locus_tag="CGSHiEE_01425"
/db_xref="GeneID:5225070"
CDS complement(267801..268037)
/locus_tag="CGSHiEE_01425"
/note="COG4456 Virulence-associated protein and related
proteins"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290148.1"
/db_xref="GI:148825395"
/db_xref="GeneID:5225070"
/translation="MLAKVFQSGNSQAVRIPMDFRFDVDTVEIFRKENGDVVLRPVSK
KTDDFLALFEGFDETFIQALEARDDLPPQERENL"
misc_feature complement(267804..268037)
/locus_tag="CGSHiEE_01425"
/note="Virulence-associated protein and related proteins
[Function unknown]; Region: VagC; COG4456"
/db_xref="CDD:34135"
gene complement(268130..268855)
/locus_tag="CGSHiEE_01430"
/db_xref="GeneID:5225071"
CDS complement(268130..268855)
/locus_tag="CGSHiEE_01430"
/note="COG0500 SAM-dependent methyltransferases"
/codon_start=1
/transl_table=11
/product="S-adenosyl-L-methionine-dependent
methyltransferase"
/protein_id="YP_001290149.1"
/db_xref="GI:148825396"
/db_xref="GeneID:5225071"
/translation="MVKDTLFSTPIAKLGDFIFDENVAEVFPDMIQRSVPGYSNIITA
IGMLAERFVTADSNVYDLGCSRGAATLSARRNIHQPNVKIIGIDNSQPMVERCCQHIA
AYHSEIPVEILCNDIRHVEIKNASMVILNFTLQFLPPEDRVALLIKIYEGLNPNGVLV
LSEKFRFEDTKVNHLLIDLHHQFKRANGYSELEVSQKRTALENVMRTDSIETHKVRLK
NIGFSQVELWFQCFNFGSMIAVK"
misc_feature complement(268370..268684)
/locus_tag="CGSHiEE_01430"
/note="S-adenosylmethionine-dependent methyltransferases
(SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
that use S-adenosyl-L-methionine (SAM or AdoMet) as a
substrate for methyltransfer, creating the product
S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
cd02440"
/db_xref="CDD:100107"
misc_feature complement(order(268463..268465,268505..268513,
268589..268594,268652..268672))
/locus_tag="CGSHiEE_01430"
/note="S-adenosylmethionine binding site [chemical
binding]; other site"
/db_xref="CDD:100107"
gene complement(268908..269426)
/locus_tag="CGSHiEE_01435"
/db_xref="GeneID:5225008"
CDS complement(268908..269426)
/locus_tag="CGSHiEE_01435"
/note="COG1755 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290150.1"
/db_xref="GI:148825397"
/db_xref="GeneID:5225008"
/translation="MLFINITFACILAIRFYSLSISIRHEKALIAKGAIQYGKRNSTL
LSIAHVAFYFAAIIEANKQNLSFNSTSQIGLAILIFAIAMLFYVIYELKEIWTVKIYI
LPEHQINRSFLFKYVRHPNYFLNIIPELIGLSLFCQAKYTALVGLPIYLLILAVRIKQ
EESAMSHLFPKS"
misc_feature complement(268911..269426)
/locus_tag="CGSHiEE_01435"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG1755"
/db_xref="CDD:31941"
gene 269647..271413
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/db_xref="GeneID:5225009"
CDS 269647..271413
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/EC_number="6.1.1.12"
/note="catalyzes a two-step reaction, first charging an
aspartate molecule by linking its carboxyl group to the
alpha-phosphate of ATP, followed by transfer of the
aminoacyl-adenylate to its tRNA; contains discriminating
and non-discriminating subtypes"
/codon_start=1
/transl_table=11
/product="aspartyl-tRNA synthetase"
/protein_id="YP_001290151.1"
/db_xref="GI:148825398"
/db_xref="GeneID:5225009"
/translation="MMRTHYCGALNRNNIGQDVTLSGWVHRRRDLGGLIFIDMRDRDG
IVQVCFDPKYQDALTAAAGLRNEFCIQIKGEVIARPENQINKNMATGEVEVLAKELRV
YNASDVLPLDFNQNNTEEQRLKYRYLDLRRPEMAQRLKTRAKITSFVRRFMDDNGFLD
IETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFR
DEDLRADRQPEFTQIDVETSFLTAPEVREIMERMVHGLWLDTIGVDLGKFPVMTWQEA
MRRFGSDKPDLRNPLEIVDVADIVKDVEFKVFNEPANNPNGRVAVIRVPNGAEITRKQ
IDEYTQFVGIYGAKGLAWAKVNDINAGLEGVQSPIAKFLNEEVWKALAERVNAQTGDI
LFFGADKWQTTTDAMGALRLKLGRDLGLTRLDEWKPLWVIDFPMFERDEEGNLAAMHH
PFTSPKDFSPEQLEADPTSAVANAYDMVINGYEVGGGSVRIFDPKMQQTVFRILGIDE
EQQREKFGFLLDALKFGTPPHAGLAFGLDRLTMLLTGTENIRDVIAFPKTTAAACLMT
EAPSFANPQALEELAIQVTKSE"
misc_feature 269647..271410
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="aspartyl-tRNA synthetase; Validated; Region: aspS;
PRK00476"
/db_xref="CDD:179042"
misc_feature 269653..270051
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="EcAspRS_like_N: N-terminal, anticodon recognition
domain of the type found in Escherichia coli aspartyl-tRNA
synthetase (AspRS), the human mitochondrial (mt) AspRS-2,
the discriminating (D) Thermus thermophilus AspRS-1, and
the nondiscriminating (ND)...; Region: EcAspRS_like_N;
cd04317"
/db_xref="CDD:58587"
misc_feature order(269653..269655,269662..269664,269716..269718,
269770..269772,269956..269958,269962..269967)
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:58587"
misc_feature order(269725..269727,269731..269739,269752..269754,
269785..269787,269839..269841,269881..269883,
269899..269901,269926..269928,269974..269976)
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="anticodon binding site; other site"
/db_xref="CDD:58587"
misc_feature 270061..>270489
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="Asp tRNA synthetase (aspRS) class II core domain.
Class II assignment is based upon its structure and the
presence of three characteristic sequence motifs. AspRS is
a homodimer, which attaches a specific amino acid to the
3' OH group of ribose of the...; Region: AspRS_core;
cd00777"
/db_xref="CDD:73228"
misc_feature order(270070..270078,270085..270087,270094..270099,
270106..270108,270115..270126,270130..270150,
270169..270171,270178..270192,270202..270213,
270256..270261,270268..270273,270289..270291,
270301..270303,270331..270333,270361..270363,
270376..270378)
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:73228"
misc_feature 270136..270150
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="motif 1; other site"
/db_xref="CDD:73228"
misc_feature order(270160..270168,270226..270228,270232..270234,
270241..270243,270298..270300,270304..270306,
270319..270327,270334..270336,270340..270342)
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="active site"
/db_xref="CDD:73228"
misc_feature 270295..270306
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="motif 2; other site"
/db_xref="CDD:73228"
misc_feature 270568..270867
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="GAD domain; Region: GAD; pfam02938"
/db_xref="CDD:145868"
misc_feature <270922..271323
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="Class II tRNA amino-acyl synthetase-like catalytic
core domain. Class II amino acyl-tRNA synthetases (aaRS)
share a common fold and generally attach an amino acid to
the 3' OH of ribose of the appropriate tRNA. PheRS is an
exception in that it attaches...; Region:
class_II_aaRS-like_core; cl00268"
/db_xref="CDD:206944"
misc_feature order(271093..271098,271108..271110,271237..271242,
271246..271251,271258..271260)
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="active site"
/db_xref="CDD:29813"
misc_feature order(271249..271251,271258..271260)
/gene="aspS"
/locus_tag="CGSHiEE_01440"
/note="motif 3; other site"
/db_xref="CDD:29813"
gene 271475..272323
/locus_tag="CGSHiEE_01445"
/db_xref="GeneID:5225010"
CDS 271475..272323
/locus_tag="CGSHiEE_01445"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290152.1"
/db_xref="GI:148825399"
/db_xref="GeneID:5225010"
/translation="MKSILKFLLFFGVSINTYAQNIQLCTDTDVKTDAEYIPKGSEIP
VYIKPSDKSEKVINETLSKAINEISYIEFSNEYVVRELCHTPNHSWSLVKAVSPSYLS
DSHVGWIKSSFLKEAKFDEKGFRIIEEEDVNWNDITKPYKKLITAELNKIHRENANCK
KIDPAVLDVSSTKGTKSNPVFYVTCGEGLSSFNVFFSLDDMNSGKSQSIEYISQQKAI
LLCEKDVERRFSKQKLVNFSKFLDVSYLQHPNGRVSLISSITLKNSHGEKDKYSIKCL
FEKIIY"
gene complement(272416..272472)
/locus_tag="CGSHiEE_01450"
/db_xref="GeneID:5225011"
CDS complement(272416..272472)
/locus_tag="CGSHiEE_01450"
/note="COG0173 Aspartyl-tRNA synthetase"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290153.1"
/db_xref="GI:148825400"
/db_xref="GeneID:5225011"
/translation="MQNNLQNYAKNFASLQLF"
gene 272906..273289
/locus_tag="CGSHiEE_01455"
/db_xref="GeneID:5225012"
CDS 272906..273289
/locus_tag="CGSHiEE_01455"
/note="COG2932 Predicted transcriptional regulator"
/codon_start=1
/transl_table=11
/product="transcriptional regulatory protein"
/protein_id="YP_001290154.1"
/db_xref="GI:148825401"
/db_xref="GeneID:5225012"
/translation="MVDCYSSINVSAGFGSFNEGATEADGQEPYSDSLLCSLGVKAEK
CAVFWANGNSMLPTINDGDQMLVDLSRKEIQGDRIYLVQNGESMWVKRVKMEWDGISL
ISDNKEKYPPISITGKDAQHLQIIG"
misc_feature <272918..273286
/locus_tag="CGSHiEE_01455"
/note="Predicted transcriptional regulator
[Transcription]; Region: COG2932"
/db_xref="CDD:32756"
misc_feature 273044..273286
/locus_tag="CGSHiEE_01455"
/note="Peptidase S24 LexA-like proteins are involved in
the SOS response leading to the repair of single-stranded
DNA within the bacterial cell. This family includes: the
lambda repressor CI/C2 family and related bacterial
prophage repressor proteins; LexA (EC...; Region:
S24_LexA-like; cd06529"
/db_xref="CDD:119397"
misc_feature order(273065..273067,273176..273178)
/locus_tag="CGSHiEE_01455"
/note="Catalytic site [active]"
/db_xref="CDD:119397"
gene complement(273414..274121)
/locus_tag="CGSHiEE_01460"
/db_xref="GeneID:5224856"
CDS complement(273414..274121)
/locus_tag="CGSHiEE_01460"
/note="COG2801 Transposase and inactivated derivatives"
/codon_start=1
/transl_table=11
/product="transposase"
/protein_id="YP_001290155.1"
/db_xref="GI:148825402"
/db_xref="GeneID:5224856"
/translation="MKKTIQRIKANHPDYGYRRVHASLPGVNHKKVQRLIQTLGLQVR
SRKSKKFTTYRGTIGHIAPNRLERDFSATAPKQKWVTDITEFKAKDGSKVYLSPILDL
FNNEIVSYNLSYSPNWAQVEDMLMQAVKGLNKACGVILHSDQGWQYQMVAYRRILAEH
GIIQSMSRKGNCLDNAAMESFFGRLKTECFYGREFNSREEIVDAVRDYLDYYNHRRIQ
LKLKGLSPIQYRKQSFK"
misc_feature complement(273975..274118)
/locus_tag="CGSHiEE_01460"
/note="HTH-like domain; Region: HTH_21; pfam13276"
/db_xref="CDD:205456"
misc_feature complement(273423..274109)
/locus_tag="CGSHiEE_01460"
/note="Transposase and inactivated derivatives [DNA
replication, recombination, and repair]; Region: Tra5;
COG2801"
/db_xref="CDD:32633"
misc_feature complement(273555..273899)
/locus_tag="CGSHiEE_01460"
/note="Integrase core domain; Region: rve; pfam00665"
/db_xref="CDD:201381"
misc_feature complement(273420..273587)
/locus_tag="CGSHiEE_01460"
/note="Integrase core domain; Region: rve_2; pfam13333"
/db_xref="CDD:205513"
gene complement(274220..274573)
/locus_tag="CGSHiEE_01465"
/db_xref="GeneID:5224857"
CDS complement(274220..274573)
/locus_tag="CGSHiEE_01465"
/codon_start=1
/transl_table=11
/product="transposase"
/protein_id="YP_001290156.1"
/db_xref="GI:148825403"
/db_xref="GeneID:5224857"
/translation="MGKHYTIEFKLQILQPILNGKMSIREAARFYNIPSNALVGTWLK
QFEKSGIKGLIPRKPSGRPPMKPKYAKMPPPPKTEEDRLRLRILQLEAEVAYLKELRR
LRLQDEAEQRKLSKG"
misc_feature complement(274388..274549)
/locus_tag="CGSHiEE_01465"
/note="Helix-turn-helix domain; Region: HTH_28; pfam13518"
/db_xref="CDD:205696"
gene 274871..276139
/gene="aspS"
/locus_tag="CGSHiEE_01470"
/db_xref="GeneID:5224858"
CDS 274871..276139
/gene="aspS"
/locus_tag="CGSHiEE_01470"
/EC_number="6.1.1.12"
/note="COG1914 Mn2+ and Fe2+ transporters of the NRAMP
family"
/codon_start=1
/transl_table=11
/product="aspartyl-tRNA synthetase"
/protein_id="YP_001290157.1"
/db_xref="GI:148825404"
/db_xref="GeneID:5224858"
/translation="MREVSTPVEKSTWASKFSALGPGIVMASAAVGGSHIIASTQAGA
IYGWELVSIVILANLFKYPFFRFGVQYTLDTGNTLLEGYRQKGKFYLWLFLALNVFAT
VINTAAVGLLTAAILTFITPIPLPMPVLSSLVILVTTGILLLGKYRLLDSLSKIIMIA
LTVTTVSAVVIAFMRNGINGVAAPDFVPPSPWELSKLAFLVALMGWMPAPIEISAINS
MWVVAKRRLTKVSYEDGLFDFNVGYIGTAILAVVFLALGALVQYGSPETVEMVGGKYI
AQLINMYASTIGEWSRLLIAVIAFMCMFGTTITVIDGYSRTNVEALRILFGKQESSVR
ILNIGMIFAALSGLAIIFYFNNAVGPMLKFAMIASFVSAPIFAWLNLSLTKHATHSVK
GGLLWLSLIGLFYLTAFAGLFIAQQAGWLN"
misc_feature 274871..276136
/gene="aspS"
/locus_tag="CGSHiEE_01470"
/note="Mn2+ and Fe2+ transporters of the NRAMP family
[Inorganic ion transport and metabolism]; Region: MntH;
COG1914"
/db_xref="CDD:32098"
misc_feature 274928..>275443
/gene="aspS"
/locus_tag="CGSHiEE_01470"
/note="manganese transport protein MntH; Reviewed; Region:
PRK00701; cl15845"
/db_xref="CDD:210245"
gene 276332..276697
/gene="ntpA"
/locus_tag="CGSHiEE_01475"
/db_xref="GeneID:5224859"
CDS 276332..276697
/gene="ntpA"
/locus_tag="CGSHiEE_01475"
/note="COG0494 NTP pyrophosphohydrolases including
oxidative damage repair enzymes"
/codon_start=1
/transl_table=11
/product="dATP pyrophosphohydrolase"
/protein_id="YP_001290158.1"
/db_xref="GI:148825405"
/db_xref="GeneID:5224859"
/translation="MILIFGSLLLAPLKVVKHQKKQAIRELWEEVRLEISENSTALFD
CNESIEFEIFPHFRYKYAPNITHCKEHWFLCEVEKEFMPVLSEHLDFCWISAKKAVEM
TKSQNNAEAIKKYLFNLRR"
misc_feature <276398..276694
/gene="ntpA"
/locus_tag="CGSHiEE_01475"
/note="Nudix hydrolase is a superfamily of enzymes found
in all three kingdoms of life, and it catalyzes the
hydrolysis of NUcleoside DIphosphates linked to other
moieties, X. Enzymes belonging to this superfamily require
a divalent cation, such as Mg2+ or Mn2+...; Region:
Nudix_Hydrolase; cl00447"
/db_xref="CDD:212606"
misc_feature 276398..276424
/gene="ntpA"
/locus_tag="CGSHiEE_01475"
/note="nudix motif; other site"
/db_xref="CDD:72880"
gene 276857..277597
/locus_tag="CGSHiEE_01480"
/db_xref="GeneID:5224860"
CDS 276857..277597
/locus_tag="CGSHiEE_01480"
/note="COG0217 Uncharacterized conserved protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290159.1"
/db_xref="GI:148825406"
/db_xref="GeneID:5224860"
/translation="MAGHSKWANIKHRKAAQDAQRGKIFTKLIRELVTAAKIGGGDVS
ANPRLRAAVDKALSNNMTRDTINRAIDRGVGGGDDTNMETKIYEGYGPGGTAVMVECL
SDNANRTISQVRPSFTKCGGNLGTEGSVGYLFSKKGLILIAEADEDALTEAAIEAGAD
DIQPQDDGSFEIYTAWEDLGSVRDGIEAAGFKVQEAEVTMIPSTTVDLDIETAPKLLR
LIDMLEDCDDVQNVYHNGEICDEVASQL"
misc_feature 276857..277594
/locus_tag="CGSHiEE_01480"
/note="hypothetical protein; Validated; Region: PRK00110"
/db_xref="CDD:178871"
gene 277644..278216
/gene="ruvC"
/locus_tag="CGSHiEE_01485"
/db_xref="GeneID:5224861"
CDS 277644..278216
/gene="ruvC"
/locus_tag="CGSHiEE_01485"
/EC_number="3.1.22.4"
/note="endonuclease; resolves Holliday structures; forms a
complex of RuvABC; the junction binding protein RuvA forms
a hexameric ring along with the RuvB helicase and
catalyzes branch migration; RuvC then interacts with RuvAB
to resolve the Holliday junction by nicking DNA strands of
like polarity"
/codon_start=1
/transl_table=11
/product="Holliday junction resolvase"
/protein_id="YP_001290160.1"
/db_xref="GI:148825407"
/db_xref="GeneID:5224861"
/translation="MSIILGIDPGSRVTGYGVIRQTGRHLEYLGSGAIRTQVEDLPTR
LKRIYAGVTEIITQFQPDMFAIEQVFMAKNADSALKLGQARGTAIVAAVNHDLPVFEY
AARLVKQTVVGIGSADKVQVQEMVTRILKLSDKPQTDAADALAIAITHAHSIQHSLHI
ANSVKMTETQEKMTALLKTRYSRGRFRLKI"
misc_feature 277650..278051
/gene="ruvC"
/locus_tag="CGSHiEE_01485"
/note="Holliday junction resolvases (HJRs) are
endonucleases that specifically resolve Holliday junction
DNA intermediates during homologous recombination. HJR's
occur in archaea, bacteria, and in the mitochondria of
certain fungi, however this CD includes...; Region:
RuvC_resolvase; cd00529"
/db_xref="CDD:29627"
misc_feature order(277665..277667,277842..277844)
/gene="ruvC"
/locus_tag="CGSHiEE_01485"
/note="active site"
/db_xref="CDD:29627"
misc_feature order(277677..277679,277746..277748,277860..277862,
277881..277883,277956..277958,277965..277967,
277998..278000)
/gene="ruvC"
/locus_tag="CGSHiEE_01485"
/note="putative DNA-binding cleft [nucleotide binding];
other site"
/db_xref="CDD:29627"
misc_feature order(277779..277781,277788..277790,277851..277853,
277866..277868,277875..277880,277887..277892,
277896..277901,277908..277910,277920..277925)
/gene="ruvC"
/locus_tag="CGSHiEE_01485"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:29627"
gene 278279..278893
/gene="ruvA"
/locus_tag="CGSHiEE_01490"
/db_xref="GeneID:5225282"
CDS 278279..278893
/gene="ruvA"
/locus_tag="CGSHiEE_01490"
/note="plays an essential role in ATP-dependent branch
migration of the Holliday junction"
/codon_start=1
/transl_table=11
/product="Holliday junction DNA helicase RuvA"
/protein_id="YP_001290161.1"
/db_xref="GI:148825408"
/db_xref="GeneID:5225282"
/translation="MIGRLQGILLEKQPPEILLNVQGVGYELLLPMTSFYDLPEIGQE
TTLFTHLVVREDAHLLFGFAQKTDRTLFRELIKTNGVGPKLALAILSAMSVEQFAYAI
EREELSKLTKIPGVGKKTAERLLVELKGKFKGVKQSDFFVESTHIPLSPSIESHSESS
SDEAISALIALGYKPVEAEKMVKRVAKPELTSEQVIREALKAAL"
misc_feature 278279..278890
/gene="ruvA"
/locus_tag="CGSHiEE_01490"
/note="Holliday junction DNA helicase RuvA; Reviewed;
Region: ruvA; PRK00116"
/db_xref="CDD:178876"
misc_feature 278279..278464
/gene="ruvA"
/locus_tag="CGSHiEE_01490"
/note="RuvA N terminal domain; Region: RuvA_N; pfam01330"
/db_xref="CDD:201732"
misc_feature <278792..278884
/gene="ruvA"
/locus_tag="CGSHiEE_01490"
/note="RuvA, C-terminal domain; Region: RuvA_C; pfam07499"
/db_xref="CDD:203653"
gene 278901..279908
/gene="ruvB"
/locus_tag="CGSHiEE_01495"
/db_xref="GeneID:5225283"
CDS 278901..279908
/gene="ruvB"
/locus_tag="CGSHiEE_01495"
/EC_number="3.1.22.4"
/note="promotes strand exchange during homologous
recombination; RuvAB complex promotes branch migration;
RuvABC complex scans the DNA during branch migration and
resolves Holliday junctions at consensus sequences; forms
hexameric rings around opposite DNA arms; requires ATP for
branch migration and orientation of RuvAB complex
determines direction of migration"
/codon_start=1
/transl_table=11
/product="Holliday junction DNA helicase RuvB"
/protein_id="YP_001290162.1"
/db_xref="GI:148825409"
/db_xref="GeneID:5225283"
/translation="MIEADRIISGQAKVDEDVIDRAIRPKLLADYVGQPQVREQMDIF
IKAAKLRQDALDHLLIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAAMLT
NLEPHDVLFIDEIHRLSPAIEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGSLTSPLRDRFGIVQRLEFYSVEDLTSIVARSAGCLNLELEQQAAFEVARRSRG
TPRIANRLLRRVRDYADVRNGGVISVDVAKQALSMLDVDDAGFDYLDRKLLSAVIERF
DGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRIATSKTYRHFGLQKLS
D"
misc_feature 278916..279896
/gene="ruvB"
/locus_tag="CGSHiEE_01495"
/note="Holliday junction DNA helicase RuvB; Reviewed;
Region: ruvB; PRK00080"
/db_xref="CDD:178847"
misc_feature 279012..279434
/gene="ruvB"
/locus_tag="CGSHiEE_01495"
/note="The AAA+ (ATPases Associated with a wide variety of
cellular Activities) superfamily represents an ancient
group of ATPases belonging to the ASCE (for additional
strand, catalytic E) division of the P-loop NTPase fold.
The ASCE division also includes ABC; Region: AAA; cd00009"
/db_xref="CDD:99707"
misc_feature 279084..279107
/gene="ruvB"
/locus_tag="CGSHiEE_01495"
/note="Walker A motif; other site"
/db_xref="CDD:99707"
misc_feature order(279087..279110,279237..279239,279384..279386)
/gene="ruvB"
/locus_tag="CGSHiEE_01495"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:99707"
misc_feature 279225..279242
/gene="ruvB"
/locus_tag="CGSHiEE_01495"
/note="Walker B motif; other site"
/db_xref="CDD:99707"
misc_feature 279420..279422
/gene="ruvB"
/locus_tag="CGSHiEE_01495"
/note="arginine finger; other site"
/db_xref="CDD:99707"
misc_feature 279669..279893
/gene="ruvB"
/locus_tag="CGSHiEE_01495"
/note="Holliday junction DNA helicase ruvB C-terminus;
Region: RuvB_C; pfam05491"
/db_xref="CDD:203257"
gene complement(279960..280247)
/gene="ruvB"
/locus_tag="CGSHiEE_01500"
/db_xref="GeneID:5225284"
CDS complement(279960..280247)
/gene="ruvB"
/locus_tag="CGSHiEE_01500"
/note="COG1196 Chromosome segregation ATPases"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290163.1"
/db_xref="GI:148825410"
/db_xref="GeneID:5225284"
/translation="MKKITLFFTALLCLFSTSVLAESNLIPKQCEQLFKETENLIAQA
EKQPGTHIQVNKIKSKLNQSKQQILQMELATQLKSCEVGLAKLSNLKSYSE"
gene complement(280420..281313)
/gene="xerD"
/locus_tag="CGSHiEE_01505"
/db_xref="GeneID:5225285"
CDS complement(280420..281313)
/gene="xerD"
/locus_tag="CGSHiEE_01505"
/note="site-specific tyrosine recombinase which cuts and
rejoins DNA molecules; binds cooperatively to specific DNA
consensus sites; forms a heterotetrameric complex with
XerC; XerCD exhibit similar sequences; essential to
convert chromosome dimers to monomers during cell division
and functions during plasmid segregation; XerD
specifically exchanges the bottom strands; cell division
protein FtsK may regulate the XerCD complex; enzyme from
Streptococcus group has unusual active site motifs"
/codon_start=1
/transl_table=11
/product="site-specific tyrosine recombinase XerD"
/protein_id="YP_001290164.1"
/db_xref="GI:148825411"
/db_xref="GeneID:5225285"
/translation="MKNLALIDLFLNEYWIEKGLSENTVQSYRLDLTALCDWLDKNDL
SLETLDAVDLQGFLGERLEKGYKATSTARMLSAMRKLFQYLYREKYRVDDPSAVLSSP
KLPSRLPKYLTEQQVSDLLNTPDVEVPLELRDKAMLELLYATGLRVTELVSLTIENMS
VQQGVVRVIGKGNKERIVPMGEEAAYWVRQFMLYGRPVLLNGQSSDVVFPSQRAQQMT
RQTFWHRVKHYAILADIDADALSPHVLRHAFATHLVNHGADLRVVQMLLGHTDLSTTQ
IYTHVAKERLKRLHERFHPRG"
misc_feature complement(280423..281313)
/gene="xerD"
/locus_tag="CGSHiEE_01505"
/note="site-specific tyrosine recombinase XerD; Reviewed;
Region: xerD; PRK00283"
/db_xref="CDD:178959"
misc_feature complement(280444..281295)
/gene="xerD"
/locus_tag="CGSHiEE_01505"
/note="XerD and XerC integrases, DNA breaking-rejoining
enzymes, N- and C-terminal domains. XerD-like integrases
are involved in the site-specific integration and excision
of lysogenic bacteriophage genomes, transposition of
conjugative transposons, termination...; Region:
INT_XerDC; cd00798"
/db_xref="CDD:29499"
misc_feature complement(order(280480..280482,280507..280509,
280576..280578,280585..280587,280801..280803,
280873..280875))
/gene="xerD"
/locus_tag="CGSHiEE_01505"
/note="Int/Topo IB signature motif; other site"
/db_xref="CDD:29499"
misc_feature complement(order(280480..280482,280573..280578,
280585..280587,280873..280875))
/gene="xerD"
/locus_tag="CGSHiEE_01505"
/note="active site"
/db_xref="CDD:29499"
gene complement(281344..282510)
/locus_tag="CGSHiEE_01510"
/db_xref="GeneID:5225286"
CDS complement(281344..282510)
/locus_tag="CGSHiEE_01510"
/note="putative transporter of 3-phenylpropionate across
the inner membrane; member of the major facilitator
superfamily of transporters"
/codon_start=1
/transl_table=11
/product="putative 3-phenylpropionic acid transporter"
/protein_id="YP_001290165.1"
/db_xref="GI:148825412"
/db_xref="GeneID:5225286"
/translation="MQLRPFYWLALSFLGYYCAYGVFLPFFPAWLKSQQYGEEMIGLV
IGSAYIFRFAGGLFFSSLIKKANHIINSLRLLALASAIIMAAMSLVAHNFWLLFIAIG
LYASVNSAGMPIGDSLASTWQRQIGLDYGKVRLIGSAAFILGVVVFGGMIGWVGEQNI
VWILTALLSFYTIIQLLKPTIPPKDEIPEGSDQNHIGFIALLKNPMTLRVMIAVGLIQ
GSHAAYYVYSTIYWTSIGISISQTSLLWGIGVLAEIVLFFFSRRLFQNISISVLLYIS
AIACVGRWAVMGYIEDFWLIFLLQLMHSLTYAVCHYAIVRYITTQPQSHIAKLQGLYN
GLSNGVLIAIFTAIAGTIYPTSPAMTFVLMSIIAAAAFFVIPRKLNAFLIVQHK"
misc_feature complement(281365..282510)
/locus_tag="CGSHiEE_01510"
/note="phenyl proprionate permease family protein; Region:
2A0127; TIGR00902"
/db_xref="CDD:129980"
misc_feature complement(281383..282495)
/locus_tag="CGSHiEE_01510"
/note="The Major Facilitator Superfamily (MFS) is a large
and diverse group of secondary transporters that includes
uniporters, symporters, and antiporters. MFS proteins
facilitate the transport across cytoplasmic or internal
membranes of a variety of...; Region: MFS; cd06174"
/db_xref="CDD:119392"
misc_feature complement(order(281497..281499,281506..281511,
281518..281523,281530..281535,281566..281568,
281575..281580,281590..281592,281599..281604,
281611..281613,281740..281742,281752..281754,
281761..281763,281773..281775,281785..281787,
281824..281826,281833..281838,281845..281850,
281857..281859,282088..282090,282106..282111,
282118..282123,282151..282153,282160..282165,
282172..282177,282184..282189,282331..282336,
282340..282345,282355..282357,282364..282369,
282376..282378,282427..282432,282436..282444,
282451..282453))
/locus_tag="CGSHiEE_01510"
/note="putative substrate translocation pore; other site"
/db_xref="CDD:119392"
gene complement(282510..283325)
/locus_tag="CGSHiEE_01515"
/db_xref="GeneID:5225250"
CDS complement(282510..283325)
/locus_tag="CGSHiEE_01515"
/EC_number="1.5.1.2"
/note="catalyzes the formation of L-proline from
pyrroline-5-carboxylate"
/codon_start=1
/transl_table=11
/product="pyrroline-5-carboxylate reductase"
/protein_id="YP_001290166.1"
/db_xref="GI:148825413"
/db_xref="GeneID:5225250"
/translation="MQHKLIAFIGGGNMAQAIILGLLKQGYPAEQIIVNDPNEEKRAF
FANLGVTTSENNVESVIKAEVVLLAVKPQMMAEVCSPLSAVDFSDKLLISIAAGISTE
RLNALIPSANAVVRVMPNTPVLVGEGMAGLFAPKNTSENHRTFAQDLLGAVGRTVWVD
DETQMHAVTAASGSSPAYFFLMLEAMQQALIKMNIEEKTARELVQQSMLGAAKMVTEN
PQIALSTLRENVTSKGGTTASALAVFDAQHFNQIIEQAMQACLSRSQEMETLF"
misc_feature complement(282516..283322)
/locus_tag="CGSHiEE_01515"
/note="pyrroline-5-carboxylate reductase; Reviewed;
Region: PRK11880"
/db_xref="CDD:183357"
misc_feature complement(282525..283310)
/locus_tag="CGSHiEE_01515"
/note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
NADB_Rossmann; cl09931"
/db_xref="CDD:213117"
misc_feature complement(order(283053..283055,283116..283121,
283215..283220,283284..283292))
/locus_tag="CGSHiEE_01515"
/note="NAD(P) binding site [chemical binding]; other site"
/db_xref="CDD:133419"
gene 283391..284299
/gene="rdgC"
/locus_tag="CGSHiEE_01520"
/db_xref="GeneID:5225251"
CDS 283391..284299
/gene="rdgC"
/locus_tag="CGSHiEE_01520"
/note="Required for efficient pilin antigenic variation"
/codon_start=1
/transl_table=11
/product="recombination associated protein"
/protein_id="YP_001290167.1"
/db_xref="GI:148825414"
/db_xref="GeneID:5225251"
/translation="MWFKNLMTYRLTKPLDWDLAQLQTQLEDCQFHPCGAQDQSKFGW
SAPLRGSDLLYFSVGKQILLIAKKEEKILPANVVKRELDDRIESLEQKENRKLKKVEK
QTLKDDVVMNLLPRAFSKNQHTALWIDTENNLVHVDAASSKRAEDALALLRKSLGSLP
VVPLAFANEPSTILTNWILQDTLPHWLLALEEAELRGSQEDSVIRCKKQPLENEEILA
LLQDGKKVVSKLALEWEDTLTFVFNEDCTIKRLKFADSIREKNDDILKEDFTQRFDAD
FVLMTGILAKLTENLLDEFGGEKTRL"
misc_feature 283391..284296
/gene="rdgC"
/locus_tag="CGSHiEE_01520"
/note="recombination associated protein; Reviewed; Region:
rdgC; PRK00321"
/db_xref="CDD:178977"
gene complement(284349..284768)
/locus_tag="CGSHiEE_01525"
/db_xref="GeneID:5225252"
CDS complement(284349..284768)
/locus_tag="CGSHiEE_01525"
/note="similar to RuvC resolvase with substantial
differences; NMR structural information suggests this
protein is monomeric; unknown cellular function"
/codon_start=1
/transl_table=11
/product="Holliday junction resolvase-like protein"
/protein_id="YP_001290168.1"
/db_xref="GI:148825415"
/db_xref="GeneID:5225252"
/translation="MGITALAFDFGTKSIGCAIGQSITGTAQALPAFKAQDGIPNWEA
IEKCLKEWKPDVVIVGLPLNMDGTEQNLTLLARKFANRLQGRFGVNVHLQDERLTTTQ
ARSEIFERGGFKALKKGKVDGISACLILESWFECTEY"
misc_feature complement(284364..284753)
/locus_tag="CGSHiEE_01525"
/note="RNAse H-fold protein YqgF; Region: RNAse_H_YqgF;
TIGR00250"
/db_xref="CDD:129352"
gene complement(284768..285328)
/locus_tag="CGSHiEE_01530"
/db_xref="GeneID:5225253"
CDS complement(284768..285328)
/locus_tag="CGSHiEE_01530"
/note="COG1678 Putative transcriptional regulator"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290169.1"
/db_xref="GI:148825416"
/db_xref="GeneID:5225253"
/translation="MMELQGKFLIAMPHLDDYFNRTVVFMCEHNEQGSMGLVINQPTD
LSIAELYSKLNFMMKNDRTFGNEMVVAGGPVHTERGFILHKNTLNAFQHTYKVTEELS
MTTSADVVETLGSTFAPEKYLVALGCSSWGAGQLEKEISDNAWLVVSSKDQILFDMPY
EDRYVAANQLLGIHPYNFALAQVGHS"
misc_feature complement(284774..285328)
/locus_tag="CGSHiEE_01530"
/note="hypothetical protein; Validated; Region: PRK00228"
/db_xref="CDD:178938"
gene complement(285325..286062)
/locus_tag="CGSHiEE_01535"
/db_xref="GeneID:5225254"
CDS complement(285325..286062)
/locus_tag="CGSHiEE_01535"
/note="in Escherichia coli RsmE methylates the N3 position
of the U1498 base in 16S rRNA; cells lacking this function
can grow, but are outcompeted by wild-type; SAM-dependent
m(3)U1498 methyltransferase"
/codon_start=1
/transl_table=11
/product="16S ribosomal RNA methyltransferase RsmE"
/protein_id="YP_001290170.1"
/db_xref="GI:148825417"
/db_xref="GeneID:5225254"
/translation="MRIPRIYHPISLENQTQCLLSEDAANHVARVLRMTEGEQLELFD
GSNHIYPAKIIESNKKSVKVEILGRELADKESNLKIHLGQVISRGERMEFTIQKSVEL
GVNVITPLWSERCGVKLDAERMDKKIQQWQKIAIAACEQCGRNSVPEIRPLMKLQDWC
AENDGALKLNLHPRAHYSIKTLPTIPSEGVRLLIGSEGGLSAQEIAQTEQQGFTEILL
GKRVLRTETASLAAITALQICFGDLGE"
misc_feature complement(285334..286059)
/locus_tag="CGSHiEE_01535"
/note="RNA methyltransferase, RsmE family; Region:
TIGR00046"
/db_xref="CDD:129157"
misc_feature complement(285331..286056)
/locus_tag="CGSHiEE_01535"
/note="16S ribosomal RNA methyltransferase RsmE;
Provisional; Region: PRK11713"
/db_xref="CDD:183286"
gene complement(286112..287680)
/gene="lnt"
/locus_tag="CGSHiEE_01540"
/db_xref="GeneID:5225255"
CDS complement(286112..287680)
/gene="lnt"
/locus_tag="CGSHiEE_01540"
/note="Transfers the fatty acyl group on membrane
lipoproteins"
/codon_start=1
/transl_table=11
/product="apolipoprotein N-acyltransferase"
/protein_id="YP_001290171.1"
/db_xref="GI:148825418"
/db_xref="GeneID:5225255"
/translation="MKNLNRILLSIKFMNKYFTYLIAIISGLLGVFAFSPFDYWPLAY
VSLLGLLYVAKNPKKSTALLSTFLWAMGFFCFGVSWLNVSIHQFGGASLGVSYFLVGL
LAAYLALYPMLFTYLVQRFKVQSAVIFAVIWTLTEFLRGWIFTGFPWLQFGYTQIDSP
FYGIAPIFGVTGLTFFTVWASAVIFNLVSSLFKTKNLKLVLANALLLIIVGGLSAYSS
RIHFVKSVEDKAILVTLAQGNIEQNLKWDPNYFYSTLAIYQKLIAENLGKTDLIILPE
SALPTLENAITPFFEGLEHAAKETKTEIMIGTVFQDTKSGKLLNSIMTAGNPDFPYQP
DTPNRYNKHHLVPFGEYVPLESILRPLNSVFNLPMSAFQSGEAVQPSLIAKKRAFSPA
ICYEIIFGEQVRQNLKQDTDYLLTLSNDAWFGDSIGPWQHLQMARMRALELGKPLIRA
TNTGISVFVDAQGKVLAQAPQFIETTLTYKIAPTEGKTPYSVLGNMPLYALSLLFLLL
HSMMAFIRRKMNIR"
misc_feature complement(286190..287647)
/gene="lnt"
/locus_tag="CGSHiEE_01540"
/note="apolipoprotein N-acyltransferase; Reviewed; Region:
lnt; PRK00302"
/db_xref="CDD:178970"
misc_feature complement(286190..286984)
/gene="lnt"
/locus_tag="CGSHiEE_01540"
/note="Apolipoprotein N-acyl transferase (class 9
nitrilases); Region: ALP_N-acyl_transferase; cd07571"
/db_xref="CDD:143595"
misc_feature complement(order(286424..286426,286487..286492,
286496..286501,286631..286633,286643..286645,
286655..286657,286853..286855))
/gene="lnt"
/locus_tag="CGSHiEE_01540"
/note="putative active site [active]"
/db_xref="CDD:143595"
misc_feature complement(order(286499..286501,286655..286657,
286853..286855))
/gene="lnt"
/locus_tag="CGSHiEE_01540"
/note="catalytic triad [active]"
/db_xref="CDD:143595"
misc_feature complement(order(286190..286192,286316..286321,
286355..286360,286364..286372,286376..286381,
286466..286471,286478..286492,286496..286498,
286607..286615,286634..286636,286643..286654))
/gene="lnt"
/locus_tag="CGSHiEE_01540"
/note="putative dimer interface [polypeptide binding];
other site"
/db_xref="CDD:143595"
gene complement(287664..288563)
/gene="lnt"
/locus_tag="CGSHiEE_01545"
/db_xref="GeneID:5225137"
CDS complement(287664..288563)
/gene="lnt"
/locus_tag="CGSHiEE_01545"
/note="COG4535 Putative Mg2+ and Co2+ transporter CorC"
/codon_start=1
/transl_table=11
/product="apolipoprotein N-acyltransferase"
/protein_id="YP_001290172.1"
/db_xref="GI:148825419"
/db_xref="GeneID:5225137"
/translation="MNDEQQNSNQPENTKKPFFQSLFGRFFQGELKNREELVEVIRDS
EQNDLIDQNTREMIEGVMEIAELRVRDIMIPRSQIIFIEDQQDLNTCLNTIIESAHSR
FPVIADADDRDNIVGILHAKDLLKFLREDAEAFDLSSLLRPVVIVPESKRVDRMLKDF
RSERFHMAIVVDEFGAVSGLVTIEDILEQIVGDIEDEFDEEEIADIRQLSRHTYAVRA
LTDIDDFNGQFNTDFDDEEVDTIGGLIMQTFGYLPKRGEEIILKNLQFKVTSADSRRL
IQLRVTVPDEHLVEMNNVDEKSE"
misc_feature complement(287673..288563)
/gene="lnt"
/locus_tag="CGSHiEE_01545"
/note="Putative Mg2+ and Co2+ transporter CorC [Inorganic
ion transport and metabolism]; Region: CorC; COG4535"
/db_xref="CDD:34182"
misc_feature complement(287997..288335)
/gene="lnt"
/locus_tag="CGSHiEE_01545"
/note="This cd contains two tandem repeats of the
cystathionine beta-synthase (CBS pair) domains associated
with the CorC_HlyC domain. CorC_HlyC is a transporter
associated domain. This small domain is found in Na+/H+
antiporters, in proteins involved in...; Region:
CBS_pair_CorC_HlyC_assoc; cd04590"
/db_xref="CDD:73090"
misc_feature complement(287712..287945)
/gene="lnt"
/locus_tag="CGSHiEE_01545"
/note="Transporter associated domain; Region: CorC_HlyC;
smart01091"
/db_xref="CDD:198159"
gene complement(289186..289746)
/locus_tag="CGSHiEE_01550"
/db_xref="GeneID:5225138"
CDS complement(289186..289746)
/locus_tag="CGSHiEE_01550"
/codon_start=1
/transl_table=11
/product="N-acetyl-anhydromuranmyl-L-alanine amidase"
/protein_id="YP_001290173.1"
/db_xref="GI:148825420"
/db_xref="GeneID:5225138"
/translation="MQKLKDIEQGILDCRQIQSPHFDKRPNPQDISLLVIHYISLPPE
QFGGGYVDDFFQGKLDPKIHPYFAEIYQMRVSAHCLIERNGRITQYVNFNDRAWHAGV
SNFQGREKCNDFAIGIELEGCNEQPFTDAQYFSLQELTNVIMKSYPKITKNRIVGHCD
ISPGRKIDPGQYFDWERYLSSVKQTV"
misc_feature complement(<289198..289731)
/locus_tag="CGSHiEE_01550"
/note="N-acetyl-anhydromuramyl-L-alanine amidase [Cell
envelope biogenesis, outer membrane]; Region: ampD;
COG3023"
/db_xref="CDD:32839"
misc_feature complement(289231..289656)
/locus_tag="CGSHiEE_01550"
/note="Peptidoglycan recognition proteins (PGRPs) are
pattern recognition receptors that bind, and in certain
cases, hydrolyze peptidoglycans (PGNs) of bacterial cell
walls. PGRPs have been divided into three classes: short
PGRPs (PGRP-S), that are small (20...; Region: PGRP;
cd06583"
/db_xref="CDD:133475"
misc_feature complement(order(289243..289245,289249..289251,
289273..289275,289516..289518,289636..289638))
/locus_tag="CGSHiEE_01550"
/note="amidase catalytic site [active]"
/db_xref="CDD:133475"
misc_feature complement(order(289243..289245,289273..289275,
289636..289638))
/locus_tag="CGSHiEE_01550"
/note="Zn binding residues [ion binding]; other site"
/db_xref="CDD:133475"
misc_feature complement(order(289243..289251,289261..289263,
289273..289275,289411..289413,289450..289455,
289474..289476,289516..289518,289528..289530,
289630..289635))
/locus_tag="CGSHiEE_01550"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:133475"
gene 289860..290000
/locus_tag="CGSHiEE_01555"
/db_xref="GeneID:5225139"
CDS 289860..290000
/locus_tag="CGSHiEE_01555"
/note="COG3023 Negative regulator of beta-lactamase
expression"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290174.1"
/db_xref="GI:148825421"
/db_xref="GeneID:5225139"
/translation="MKLTTQQTLKKGFTLIELMIVIAIIAILATIAIPSYQNYTKKDS
GI"
gene 290035..290310
/locus_tag="CGSHiEE_01560"
/db_xref="GeneID:5225140"
CDS 290035..290310
/locus_tag="CGSHiEE_01560"
/note="COG4969 Tfp pilus assembly protein, major pilin
PilA"
/codon_start=1
/transl_table=11
/product="type IV pilin subunit protein"
/protein_id="YP_001290175.1"
/db_xref="GI:148825422"
/db_xref="GeneID:5225140"
/translation="MELCVYSTNEATKCTGGKNGIAADITTAKGYVKSVTTSNGAITV
KGDGTLANMEYILQASGNAATGVTWTTTCKGTDASLFPANFCGSVTQ"
misc_feature <290038..>290226
/locus_tag="CGSHiEE_01560"
/note="putative major pilin subunit; Provisional; Region:
PRK10574"
/db_xref="CDD:182560"
gene 290307..291704
/locus_tag="CGSHiEE_01565"
/db_xref="GeneID:5225141"
CDS 290307..291704
/locus_tag="CGSHiEE_01565"
/note="COG2804 Type II secretory pathway, ATPase PulE/Tfp
pilus assembly pathway, ATPase PilB"
/codon_start=1
/transl_table=11
/product="putative type IV pilin secretion protein"
/protein_id="YP_001290176.1"
/db_xref="GI:148825423"
/db_xref="GeneID:5225141"
/translation="MTSYALLHTQRVTAQNGEIFTISSDLWARNQQQQSLLLRYFALP
LKEENNRLWLGVDSLSNLSACETISFITGKPVEPILLESSQLKELLQQLTPHQMQEEE
QVKYYQHQEQSHLEQQDDEPVIRLLNQIFESALQKNASDIHLETLADQFQVRFRIDGV
LQPQPLISKIFANRIISRLKLLAKLDISENRLPQDGRFQFKTTFSDILDFRLSTLPTH
WGEKIVLRAQQNKPVELSFAELGMTENQQQAFQRALSQPQGLILVTGPTGSGKSISLY
TALQWLNTPDKHIMTAEDPIEIELDGIIQSQINPQIGLDFSRLLRTFLRQDPDIIMLG
EIRDEESARIALRAAQTGHLVLSTLHTNDAISAISRLQQLGIQQYEIENSLLLVIAQR
LVRKLCSKCGGNLINSCDCHQGYRGRIGVYQFLHWQQNGYQTDFENLRESGLEKVSQG
ITDEKEIERVLGKNL"
misc_feature 290364..291692
/locus_tag="CGSHiEE_01565"
/note="Type II secretory pathway, ATPase PulE/Tfp pilus
assembly pathway, ATPase PilB [Cell motility and secretion
/ Intracellular trafficking and secretion]; Region: PulE;
COG2804"
/db_xref="CDD:32635"
misc_feature <290409..290543
/locus_tag="CGSHiEE_01565"
/note="Type II secretion system (T2SS), protein E,
N-terminal domain; Region: T2SE_Nter; pfam05157"
/db_xref="CDD:203183"
misc_feature 290838..291584
/locus_tag="CGSHiEE_01565"
/note="PulE/GspE The type II secretory pathway is the main
terminal branch of the general secretory pathway (GSP).
It is responsible for the export the majority of
Gram-negative bacterial exoenzymes and toxins. PulE is a
cytoplasmic protein of the GSP, which...; Region:
PulE-GspE; cd01129"
/db_xref="CDD:29995"
misc_feature 291099..291122
/locus_tag="CGSHiEE_01565"
/note="Walker A motif; other site"
/db_xref="CDD:29995"
misc_feature order(291102..291104,291114..291122,291177..291179,
291183..291188,291306..291311)
/locus_tag="CGSHiEE_01565"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:29995"
misc_feature 291294..291311
/locus_tag="CGSHiEE_01565"
/note="Walker B motif; other site"
/db_xref="CDD:29995"
gene 291701..292918
/locus_tag="CGSHiEE_01570"
/db_xref="GeneID:5225142"
CDS 291701..292918
/locus_tag="CGSHiEE_01570"
/note="COG1459 Type II secretory pathway, component PulF"
/codon_start=1
/transl_table=11
/product="putative type IV pilin secretion protein"
/protein_id="YP_001290177.1"
/db_xref="GI:148825424"
/db_xref="GeneID:5225142"
/translation="MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRELTHIKL
QQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSLQILQQNCTQIMLNEWLERLLQS
IESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGI
LLFFALSFVLFYYFYLKRQIWFHQKKNQLISVTPIFGTIQKLSRLVNFSQSLQIMLQA
GVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGYAFSNSVSSDLFPME
AQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMG
MYLPIFNMGSVIQ"
misc_feature 291707..292915
/locus_tag="CGSHiEE_01570"
/note="Type II secretory pathway, component PulF [Cell
motility and secretion / Intracellular trafficking and
secretion]; Region: PulF; COG1459"
/db_xref="CDD:31648"
misc_feature 291884..292255
/locus_tag="CGSHiEE_01570"
/note="Type II secretion system (T2SS), protein F; Region:
T2SF; pfam00482"
/db_xref="CDD:201255"
misc_feature 292496..292828
/locus_tag="CGSHiEE_01570"
/note="Type II secretion system (T2SS), protein F; Region:
T2SF; pfam00482"
/db_xref="CDD:201255"
gene 292915..293523
/locus_tag="CGSHiEE_01575"
/db_xref="GeneID:5225094"
CDS 292915..293523
/locus_tag="CGSHiEE_01575"
/note="COG1835 Predicted acyltransferases"
/codon_start=1
/transl_table=11
/product="N-acetyl-anhydromuranmyl-L-alanine amidase"
/protein_id="YP_001290178.1"
/db_xref="GI:148825425"
/db_xref="GeneID:5225094"
/translation="MIYFTMFLLGGIFGIALWFYLSGFITRLQQEIYATYIELFPQNF
LPFQPSVSSIQQKKCGHILRYFLNVGVGFIFLQIAFKDSIFAIWLGLTLLILWAISYL
DWYYQLISTTPCLWLLTIGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKFYYG
KEAFGRGDYWLAMALGSFIHLETLPHFFIISLSSWNMFFAYS"
misc_feature 292915..>293487
/locus_tag="CGSHiEE_01575"
/note="Type II secretory pathway, prepilin signal
peptidase PulO and related peptidases [Cell motility and
secretion / Posttranslational modification, protein
turnover, chaperones / Intracellular trafficking and
secretion]; Region: PulO; COG1989"
/db_xref="CDD:32172"
misc_feature 293185..293487
/locus_tag="CGSHiEE_01575"
/note="Type IV leader peptidase family; Region:
Peptidase_A24; pfam01478"
/db_xref="CDD:144901"
gene complement(293662..294924)
/gene="rho"
/locus_tag="CGSHiEE_01580"
/db_xref="GeneID:5225095"
CDS complement(293662..294924)
/gene="rho"
/locus_tag="CGSHiEE_01580"
/note="An RNA-DNA helicase that actively releases nascent
mRNAs from paused transcription complexes"
/codon_start=1
/transl_table=11
/product="transcription termination factor Rho"
/protein_id="YP_001290179.1"
/db_xref="GI:148825426"
/db_xref="GeneID:5225095"
/translation="MHLTELKNTPVSDLVKLGEEQMGLENLARLRKQDIVFAILKQHA
KSGEDIFGGGVLEILPDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLQTGDKIEGKI
RPPKEGERYFALLKVDQVNDDKPEVSRSKILFENLTPLHANSRLRMERGNGSTEDLTA
RILDLASPIGKGQRGLIVAPPKAGKTMLLQNIAQSITHNYPDVELIVLLIDERPEEVT
EMQRSVKGEVIASTFDEPATRHVQVAEMVIEKAKRSVEHKKDVVILLDSITRLARAYN
TVTPASGKILSGGVDANALHRPKRFFGAARNVEEGGSLTIIATALVDTGSKMDEVIFE
EFKGTGNMELHLSRKIAERRVFPAIDFKRSGTRKEDLLTTADELQKMWILRKILNPMD
EVDAMEFLIDKLMMAKTNEEFFEVMKRS"
misc_feature complement(293668..294924)
/gene="rho"
/locus_tag="CGSHiEE_01580"
/note="transcription termination factor Rho; Provisional;
Region: rho; PRK09376"
/db_xref="CDD:181809"
misc_feature complement(294781..294912)
/gene="rho"
/locus_tag="CGSHiEE_01580"
/note="Rho termination factor, N-terminal domain; Region:
Rho_N; smart00959"
/db_xref="CDD:198027"
misc_feature complement(294571..294771)
/gene="rho"
/locus_tag="CGSHiEE_01580"
/note="Rho_CSD: Rho protein cold-shock domain (CSD). Rho
protein is a transcription termination factor in most
bacteria. In bacteria, there are two distinct mechanisms
for mRNA transcription termination. In intrinsic
termination, RNA polymerase and nascent mRNA...; Region:
Rho_CSD; cd04459"
/db_xref="CDD:88425"
misc_feature complement(order(294592..294600,294607..294609,
294682..294684,294688..294690,294724..294726,
294730..294732,294736..294738,294748..294750,
294754..294756))
/gene="rho"
/locus_tag="CGSHiEE_01580"
/note="RNA binding site [nucleotide binding]; other site"
/db_xref="CDD:88425"
misc_feature complement(293713..294456)
/gene="rho"
/locus_tag="CGSHiEE_01580"
/note="Transcription termination factor rho is a bacterial
ATP-dependent RNA/DNA helicase. It is a homohexamer. Each
monomer consists of an N-terminal domain of the OB fold,
which is responsible for binding to cysteine rich
nucleotides. This alignment is of the...; Region:
rho_factor; cd01128"
/db_xref="CDD:29994"
misc_feature complement(order(293767..293769,293779..293781,
293821..293826,293896..293898,293902..293916,
293920..293925,293998..294000,294007..294009,
294016..294018,294025..294030,294037..294039,
294070..294072,294403..294405))
/gene="rho"
/locus_tag="CGSHiEE_01580"
/note="multimer interface [polypeptide binding]; other
site"
/db_xref="CDD:29994"
misc_feature complement(294367..294390)
/gene="rho"
/locus_tag="CGSHiEE_01580"
/note="Walker A motif; other site"
/db_xref="CDD:29994"
misc_feature complement(order(293857..293859,294364..294375,
294379..294381))
/gene="rho"
/locus_tag="CGSHiEE_01580"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:29994"
misc_feature complement(294127..294141)
/gene="rho"
/locus_tag="CGSHiEE_01580"
/note="Walker B motif; other site"
/db_xref="CDD:29994"
gene 295174..295491
/locus_tag="CGSHiEE_01585"
/db_xref="GeneID:5225096"
CDS 295174..295491
/locus_tag="CGSHiEE_01585"
/note="when combined with S-adenosylmethionine represses
the expression of the methionine regulon and of proteins
involved in S-adenosylmethionine synthesis"
/codon_start=1
/transl_table=11
/product="transcriptional repressor protein MetJ"
/protein_id="YP_001290180.1"
/db_xref="GI:148825427"
/db_xref="GeneID:5225096"
/translation="MANWDGKYISPYAEHGKKSEQVKKITVSIPIKVLEILTNERTRR
QLKSLRHATNSELLCEAFLHAFTGQPLPTDADLMKERNDEIPEDAKVLMRELGVDPES
WEY"
misc_feature 295177..295485
/locus_tag="CGSHiEE_01585"
/note="Met Repressor, MetJ. MetJ is a bacterial
regulatory protein that uses S-adenosylmethionine (SAM) as
a corepressor to regulate the production of Methionine.
MetJ binds arrays of two to five adjacent copies of an
eight base-pair 'metbox' sequence. MetJ...; Region:
Met_repressor_MetJ; cd00490"
/db_xref="CDD:119402"
misc_feature order(295201..295206,295210..295212,295231..295266,
295270..295275,295279..295284,295291..295293,
295336..295338,295345..295350,295354..295359,
295363..295371,295384..295386)
/locus_tag="CGSHiEE_01585"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:119402"
misc_feature order(295225..295227,295237..295251,295255..295257,
295294..295296,295330..295338)
/locus_tag="CGSHiEE_01585"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:119402"
misc_feature order(295291..295293,295300..295305,295342..295344,
295351..295359,295363..295371,295375..295377,
295384..295389)
/locus_tag="CGSHiEE_01585"
/note="corepressor binding sites; other site"
/db_xref="CDD:119402"
gene complement(295505..295891)
/locus_tag="CGSHiEE_01590"
/db_xref="GeneID:5225097"
CDS complement(295505..295891)
/locus_tag="CGSHiEE_01590"
/note="COG0789 Predicted transcriptional regulators"
/codon_start=1
/transl_table=11
/product="transcriptional regulator MerR family protein"
/protein_id="YP_001290181.1"
/db_xref="GI:148825428"
/db_xref="GeneID:5225097"
/translation="MNISEAAKLVGLSTKQIRDYEKMGLIKPAVRSLSGYRNYGESDL
ERLHFIRHSRNVGFSLHQIAQLLALQDNPKRSCREVKVLTAQHIATLNQQIEQLQKMV
QKLQHWHDSCQGNDNPECLILNGLNG"
misc_feature complement(295511..295891)
/locus_tag="CGSHiEE_01590"
/note="Helix-Turn-Helix DNA binding domain of CueR-like
transcription regulators; Region: HTH_CueR; cd01108"
/db_xref="CDD:133383"
misc_feature complement(295514..295891)
/locus_tag="CGSHiEE_01590"
/note="Cu(I)-responsive transcriptional regulator; Region:
CueR; TIGR02044"
/db_xref="CDD:131099"
misc_feature complement(order(295781..295789,295838..295840,
295880..295888))
/locus_tag="CGSHiEE_01590"
/note="DNA binding residues [nucleotide binding]"
/db_xref="CDD:133383"
misc_feature complement(order(295514..295519,295526..295528,
295532..295534,295538..295552,295565..295567,
295586..295591,295598..295600,295610..295612,
295628..295630,295640..295642,295649..295651,
295658..295663,295682..295684,295694..295696,
295721..295726,295736..295738,295745..295747))
/locus_tag="CGSHiEE_01590"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:133383"
misc_feature complement(order(295532..295534,295556..295558,
295661..295663))
/locus_tag="CGSHiEE_01590"
/note="copper binding site [ion binding]; other site"
/db_xref="CDD:133383"
gene 295968..296174
/locus_tag="CGSHiEE_01595"
/db_xref="GeneID:5225098"
CDS 295968..296174
/locus_tag="CGSHiEE_01595"
/note="COG2608 Copper chaperone"
/codon_start=1
/transl_table=11
/product="mercuric ion scavenger protein"
/protein_id="YP_001290182.1"
/db_xref="GI:148825429"
/db_xref="GeneID:5225098"
/translation="MKTITLNIKGIHCGCCVKSLTQVLTELDGVQSADVQLEGKANIT
FDENRVNVAQLIEVIEDAGFDATE"
misc_feature 295980..296168
/locus_tag="CGSHiEE_01595"
/note="Heavy-metal-associated domain (HMA) is a conserved
domain of approximately 30 amino acid residues found in a
number of proteins that transport or detoxify heavy
metals, for example, the CPx-type heavy metal ATPases and
copper chaperones. HMA domain...; Region: HMA; cd00371"
/db_xref="CDD:29471"
misc_feature order(295998..296006,296013..296015)
/locus_tag="CGSHiEE_01595"
/note="metal-binding site [ion binding]"
/db_xref="CDD:29471"
gene 296260..296466
/locus_tag="CGSHiEE_01600"
/db_xref="GeneID:5225077"
CDS 296260..296466
/locus_tag="CGSHiEE_01600"
/note="COG2608 Copper chaperone"
/codon_start=1
/transl_table=11
/product="mercuric ion scavenger protein"
/protein_id="YP_001290183.1"
/db_xref="GI:148825430"
/db_xref="GeneID:5225077"
/translation="MKTITLNIKGIHCGCCVKSLTQVLTELDGVQSADVQLEGKANIT
FDENRVNVAQLIEVIEDAGFDATE"
misc_feature 296272..296460
/locus_tag="CGSHiEE_01600"
/note="Heavy-metal-associated domain (HMA) is a conserved
domain of approximately 30 amino acid residues found in a
number of proteins that transport or detoxify heavy
metals, for example, the CPx-type heavy metal ATPases and
copper chaperones. HMA domain...; Region: HMA; cd00371"
/db_xref="CDD:29471"
misc_feature order(296290..296298,296305..296307)
/locus_tag="CGSHiEE_01600"
/note="metal-binding site [ion binding]"
/db_xref="CDD:29471"
gene 296552..296758
/locus_tag="CGSHiEE_01605"
/db_xref="GeneID:5225078"
CDS 296552..296758
/locus_tag="CGSHiEE_01605"
/note="COG2608 Copper chaperone"
/codon_start=1
/transl_table=11
/product="mercuric ion scavenger protein"
/protein_id="YP_001290184.1"
/db_xref="GI:148825431"
/db_xref="GeneID:5225078"
/translation="MKTITLNIKGIHCGCCVKSLTQVLTELDGVQSADVQLEGKANIT
FDENRVNVAQLIEVIEDAGFDATE"
misc_feature 296564..296752
/locus_tag="CGSHiEE_01605"
/note="Heavy-metal-associated domain (HMA) is a conserved
domain of approximately 30 amino acid residues found in a
number of proteins that transport or detoxify heavy
metals, for example, the CPx-type heavy metal ATPases and
copper chaperones. HMA domain...; Region: HMA; cd00371"
/db_xref="CDD:29471"
misc_feature order(296582..296590,296597..296599)
/locus_tag="CGSHiEE_01605"
/note="metal-binding site [ion binding]"
/db_xref="CDD:29471"
gene 296733..298901
/locus_tag="CGSHiEE_01610"
/db_xref="GeneID:5225079"
CDS 296733..298901
/locus_tag="CGSHiEE_01610"
/note="COG2217 Cation transport ATPase"
/codon_start=1
/transl_table=11
/product="putative cation-transporting ATPase"
/protein_id="YP_001290185.1"
/db_xref="GI:148825432"
/db_xref="GeneID:5225079"
/translation="MLDLTPQSKKISIQIGGMTCQSCANRIEKVLNKKPFVQQAGVNF
AVEEAQVVFDATQASETQIIEIIHKTGFSAHIKQANELPIEENTSIPWRLIILWIINI
PFLIGMLGMMSGSHHLMLPPIWQFALASIVQLWLAIPFYRGAIGSIRGGLANMDVLVS
TGTLTIYLYSAFMLFYHADHAMGHVYFEASVMVIGFVSLGKFLEDRTKKHSLNSLSML
LQLTPKKVTVLRNEKWSEIALDQVNIGEIIRANQGERIAADGIIESGNGWCDESHLTG
ESRPEEKQKGGKVLAGAMVTEGSIIYRANQLGSQTLLGDMMNALSDAQGSKAPIARFA
DKVASVFVPVVLVISLVTFALTYILTNNNVSSLIHAVSVLVIACPCALGLATPAAIMV
GLGKAVNAGVWFKDAAAMEETAHVDTVVLDKTGTLTKGELEISALWQPQSAVYSEDDL
YRFAAAVERQANHPIAKAIVQAAEQKMLEIPTALFSKMEVGQGIQAELEQVGTIKVGK
PDYCGLILPKNLEDIWQIASIVAVSINDEPIGAFALTDTLKNDSLHAIQRLQQQNIDV
VIMSGDQQSVVDYIAKQLGIKKAFGGLSPRDKAEQIQKLKDLGHIVAMVGDGINDAPA
LASANVSFAMKSGSDIAEQTASATLMQHSVNQLVDALFIARATLKNIKQNLFFALIYN
ILGIPLAAFGFLSPIIAGAAMALSSISVLMNALRLKKVRF"
misc_feature 296757..298889
/locus_tag="CGSHiEE_01610"
/note="Cation transport ATPase [Inorganic ion transport
and metabolism]; Region: ZntA; COG2217"
/db_xref="CDD:32399"
misc_feature 296766..296957
/locus_tag="CGSHiEE_01610"
/note="Heavy-metal-associated domain (HMA) is a conserved
domain of approximately 30 amino acid residues found in a
number of proteins that transport or detoxify heavy
metals, for example, the CPx-type heavy metal ATPases and
copper chaperones. HMA domain...; Region: HMA; cd00371"
/db_xref="CDD:29471"
misc_feature order(296784..296792,296799..296801)
/locus_tag="CGSHiEE_01610"
/note="metal-binding site [ion binding]"
/db_xref="CDD:29471"
misc_feature 297306..297968
/locus_tag="CGSHiEE_01610"
/note="E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122"
/db_xref="CDD:201018"
misc_feature <298392..>298622
/locus_tag="CGSHiEE_01610"
/note="Haloacid Dehalogenase-like Hydrolases; Region:
HAD_like; cl11391"
/db_xref="CDD:212620"
gene 299124..300362
/locus_tag="CGSHiEE_01615"
/db_xref="GeneID:5225080"
CDS 299124..300362
/locus_tag="CGSHiEE_01615"
/note="COG0814 Amino acid permeases"
/codon_start=1
/transl_table=11
/product="serine transporter"
/protein_id="YP_001290186.1"
/db_xref="GI:148825433"
/db_xref="GeneID:5225080"
/translation="MKSTEKLKWNKFDATWMLNLFGTAVGAGVLFLPINAGMGGFWPL
VLMAIIVGPMTYFAHRGLAYFVLSSKNPGSDITEVVEEHFGKTAGKLITLLYFFAIFP
ILLIYGNGITNTVDSFIVNQLGMASPNRVILSFVLIAVLISVMLFNEKVMLKITEWLV
YPLVLILFVLSIYLIPEWNSAVLYELPTAGGFLTTLWLTIPVLVFSFNHSPAISSFTC
SQFREYKTFEGAERHISHTEKGASTILLFFVMFFVFSCVLTLTPEELVAAKEQNISIL
SFLANKFDNPYISYFGPLVAFLAITSSFFGHYMGAREGLEGLYLKMKGEAVNRKKLNY
ATALFFLLTLWGVAIINPSILGLIESLGGPIIAMILFIMPMYAIRKIPAMKRYSGRFS
NVFVTIMGLIAISAVVYGLL"
misc_feature 299133..300359
/locus_tag="CGSHiEE_01615"
/note="Amino acid permeases [Amino acid transport and
metabolism]; Region: SdaC; COG0814"
/db_xref="CDD:31156"
misc_feature 299148..300329
/locus_tag="CGSHiEE_01615"
/note="serine transporter; Region: stp; TIGR00814"
/db_xref="CDD:162053"
gene 300396..301763
/locus_tag="CGSHiEE_01620"
/db_xref="GeneID:5225081"
CDS 300396..301763
/locus_tag="CGSHiEE_01620"
/note="COG1760 L-serine deaminase"
/codon_start=1
/transl_table=11
/product="L-serine deaminase"
/protein_id="YP_001290187.1"
/db_xref="GI:148825434"
/db_xref="GeneID:5225081"
/translation="MISVFDMFKVGIGPSSSHTVGPMKAGKQFIDDLIKRNQFEQTTE
IHVDVYGSLSMTGRGHSTDIAIIMGLAGYLPHNVDIDMISGFIEKVKQTALLPINVGQ
KIVKFDFENNLIFHRTFLKLHENGMTITALDENRTELYRQTYYSIGGGFIVDEAHFGK
EEKNTVQVPYPYKNAEDILKHCSDNGLMLSTVMLENEIALNGKEAVSAHIENVWKTMQ
ACIEHGIHTEGILPGPLKVPRRAASLYRMLQANTNLSNDPMRVIDWVNMFALAVNEEN
AAGGRVVTAPTNGACGIIPAVLAYYEKFISPLTSEIIERYLLAAGMIGSLYKMNASIS
GAEVGCQGEVGVACSMAAAGLAEILGGNPLQVCIAAEIAMEHNLGLTCDPVGGQVQVP
CIERNAIASVKAINASRMALRRTTNPRVSLDKVIETMYETGKDMNAKYRETSQGGLAV
KIVCN"
misc_feature 300399..301751
/locus_tag="CGSHiEE_01620"
/note="L-serine dehydratase, iron-sulfur-dependent, single
chain form; Region: sda_mono; TIGR00720"
/db_xref="CDD:188076"
misc_feature 300402..300875
/locus_tag="CGSHiEE_01620"
/note="Serine dehydratase beta chain; Region: SDH_beta;
pfam03315"
/db_xref="CDD:202592"
misc_feature 300945..301748
/locus_tag="CGSHiEE_01620"
/note="Serine dehydratase alpha chain; Region: SDH_alpha;
pfam03313"
/db_xref="CDD:202591"
gene complement(301889..303145)
/locus_tag="CGSHiEE_01625"
/db_xref="GeneID:5225082"
CDS complement(301889..303145)
/locus_tag="CGSHiEE_01625"
/note="COG0814 Amino acid permeases"
/codon_start=1
/transl_table=11
/product="tryptophan-specific transport protein"
/protein_id="YP_001290188.1"
/db_xref="GI:148825435"
/db_xref="GeneID:5225082"
/translation="MTQHKSPSLLGGAMIIAGTAIGAGMLANPTSTAGVWFIGSILAL
IYTWFCMTTSGLMILEANLHYPTGSSFDTIVKDLLGKSWNIINGLSVAFVLYILTYAY
ITSGGGITQNLLNQAFSSVESAVDIGRTSGSLIFCLILAAFVWLSTKAVDRFTTVLIV
GMVVAFFLSTIGLLSSVKTEVLFNTVSQSEQTYLPYLLTALPVCLVSFGFHGNVPSLV
KYYDRDGRRVMKSIFIGTGLALVIYILWQLAVQGNLPRTEFAPVIEKGGDVSALLEAL
HKYIEVEYLSVALNFFAYMAISTSFLGVTLGLFDYIADLFKFDDSLLGRTKTTLVTFL
PPLLLSLQFPYGFVIAIGYAGLAATIWAAIVPALLAKASRQKFPQASYKVYGGNFMIG
FVMLFGILNIVAQIGANLGWFASFTG"
misc_feature complement(301931..303064)
/locus_tag="CGSHiEE_01625"
/note="Tryptophan/tyrosine permease family; Region:
Trp_Tyr_perm; pfam03222"
/db_xref="CDD:112053"
misc_feature complement(301952..303064)
/locus_tag="CGSHiEE_01625"
/note="aromatic amino acid transport protein; Region:
araaP; TIGR00837"
/db_xref="CDD:162061"
gene complement(303263..304477)
/locus_tag="CGSHiEE_01630"
/db_xref="GeneID:5224986"
CDS complement(303263..304477)
/locus_tag="CGSHiEE_01630"
/EC_number="2.6.1.2"
/note="broad specificity; family IV; in Corynebacterium
glutamicum this protein can use glutamate,
2-aminobutyrate, and aspartate as amino donors and
pyruvate as the acceptor"
/codon_start=1
/transl_table=11
/product="aminotransferase AlaT"
/protein_id="YP_001290189.1"
/db_xref="GI:148825436"
/db_xref="GeneID:5224986"
/translation="MRLFPKSDKLEHVCYDIRGPVHKEALRLEEEGNKILKLNIGNPA
PFGFEAPDEILVDVLRNLPSAQGYCDSKGLYSARKAIVQYYQSKGIHGATVNDVYIGN
GVSELITMAMQALLNDGDEVLVPMPDYPLWTAAVTLSGGKAVHYLCDEEANWFPAIDD
IKAKVNAKTKAIVIINPNNPTGAVYSKELLQEIVEIARQNNLIIFADEIYDKILYDGA
VHHHIAALAPDLLTVTLNGLSKAYRVAGFRQGWMILNGPKHNAKGYIEGLDMLASMRL
CANVPMQHAIQTALGGYQSINEFILPGGRLLEQRNKAYDLITQIPGITCVKPMGAMYM
FPKIDVKKFNIHSDEKMVLDLLRQEKVLLVHGKGFNWHSPDHFRVVTLPYVNQLEEAI
TKLARFLSDYRQ"
misc_feature complement(303269..304456)
/locus_tag="CGSHiEE_01630"
/note="Aspartate/tyrosine/aromatic aminotransferase [Amino
acid transport and metabolism]; Region: COG0436"
/db_xref="CDD:30785"
misc_feature complement(303287..304372)
/locus_tag="CGSHiEE_01630"
/note="Aspartate aminotransferase family. This family
belongs to pyridoxal phosphate (PLP)-dependent aspartate
aminotransferase superfamily (fold I). Pyridoxal phosphate
combines with an alpha-amino acid to form a compound
called a Schiff base or aldimine...; Region: AAT_like;
cd00609"
/db_xref="CDD:99734"
misc_feature complement(order(303734..303736,303758..303763,
303767..303769,303848..303850,303941..303943,
304091..304093,304163..304171))
/locus_tag="CGSHiEE_01630"
/note="pyridoxal 5'-phosphate binding site [chemical
binding]; other site"
/db_xref="CDD:99734"
misc_feature complement(order(303623..303625,303632..303634,
303734..303742,303869..303871,304061..304063,
304160..304162))
/locus_tag="CGSHiEE_01630"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:99734"
misc_feature complement(303758..303760)
/locus_tag="CGSHiEE_01630"
/note="catalytic residue [active]"
/db_xref="CDD:99734"
gene 304612..305904
/locus_tag="CGSHiEE_01635"
/db_xref="GeneID:5224987"
CDS 304612..305904
/locus_tag="CGSHiEE_01635"
/EC_number="2.6.1.1"
/note="COG1169 Isochorismate synthase"
/codon_start=1
/transl_table=11
/product="menaquinone-specific isochorismate synthase"
/protein_id="YP_001290190.1"
/db_xref="GI:148825437"
/db_xref="GeneID:5224987"
/translation="MYLKQNLMSYLAQAIGELKSKIHAYLQQSTNELVRFQVKLDKVD
LLAWLKSQSAYPQFYLHFRDEEKALAALGEVQSFSQLNLAQEFIEESGFPLVGGLQFQ
GTAQFVLPKILVEQDEKGALVSFFVKDEQSANDTLAHLKTFENITALSALPKQIPLHT
EPRANERTWCDWVNQALVEIKSGELTKIVLANETTFHLKQAINAYDFLAESEKQNQGC
YHFLWAENPYSVFVGSTPERLFAREYNLLLTEALAGTASVSESEEETQSQANWLLNDE
KNLKENWLVVEDISQNLRQQVESFDVSNVELKPLRKVQHLIRKIRANLTAHYADVNIL
KAIHPTAAVSGLPQQQAKMILSEIETFDRGWYAGTLGVMSDVGSQFCVAIRSAFIEAH
RIRVFAGAGIVAGSQPLEEWKEIERKAAGLISLFAEEK"
misc_feature 304654..305901
/locus_tag="CGSHiEE_01635"
/note="Isochorismate synthase [Coenzyme metabolism /
Secondary metabolites biosynthesis, transport, and
catabolism]; Region: MenF; COG1169"
/db_xref="CDD:31363"
misc_feature 304888..305889
/locus_tag="CGSHiEE_01635"
/note="isochorismate synthases; Region: isochor_syn;
TIGR00543"
/db_xref="CDD:161918"
gene 305919..307625
/locus_tag="CGSHiEE_01640"
/db_xref="GeneID:5224988"
CDS 305919..307625
/locus_tag="CGSHiEE_01640"
/EC_number="4.1.1.71"
/note="SEPHCHC synthase; forms
5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-
carboxylate from 2-oxoglutarate and isochorismate in
menaquinone biosynthesis"
/codon_start=1
/transl_table=11
/product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
cyclohexene-1-carboxylate synthase"
/protein_id="YP_001290191.1"
/db_xref="GI:148825438"
/db_xref="GeneID:5224988"
/translation="MSVSVFNRCWSKVILETLVRQGVSHVCIAPGSRSTPLTLEAVRL
QNAGSVTCYTHFDERGLGFFALGIAKATQSPVAIIVTSGTATANLYPAIIEARQTGVN
LFVLTADRPPELWECGANQAILQQNMFGQYPVANVNLPKPKADYSAQWLISLLEQAAF
QQKQQGGVVHINVPFSEPLYDATDEAVDSHSWLQPLQRWLIQTKPWMNVEAQQNEVLM
HENWDHWRTKRGVVVVGQLPAEQAMGINSWASAMGWVLLTDIQSGVVPTTPYEDIWLA
NQTVREKLLQADIVIQFGARFISKRINQFLQAFKGEFWLVEQSGKALDPYHHSLTRFN
AKAHHWLRAHPPLRQKPWLLEPLALSKFCATFIEQQVGGNLTEASFALRLPTLLPYNG
VLFLGNSLLVRLVDALTQLPESYPVYTNRGASGIDGLLATAAGIGIGSNKPVVAVIGD
TSTLYDLNSFALFKNVTQPTVIFVINNNGGAIFDMLPVDEQVKDQFYRLPHNGDFSQI
AAMFDLKYAHPYTWADLNSVVKQAYSRRKATLIEIKTNPSDGSSLYKRLIEQISHAVI
GA"
misc_feature 305919..307613
/locus_tag="CGSHiEE_01640"
/note="2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
carboxylate synthase; Validated; Region: PRK07449"
/db_xref="CDD:180980"
misc_feature 305955..306443
/locus_tag="CGSHiEE_01640"
/note="Pyrimidine (PYR) binding domain of
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-
carboxylate synthase (MenD) and related proteins; Region:
TPP_PYR_MenD; cd07037"
/db_xref="CDD:132920"
misc_feature order(306000..306002,306006..306011,306021..306023,
306072..306074,306078..306095,306168..306170,
306177..306182,306186..306191,306198..306200,
306255..306257,306276..306281,306288..306290,
306300..306302,306309..306314)
/locus_tag="CGSHiEE_01640"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:132920"
misc_feature order(306000..306002,306006..306011,306021..306023,
306072..306074,306078..306095,306168..306170,
306177..306182,306186..306191,306198..306200,
306255..306257,306276..306281,306288..306290,
306300..306302,306309..306314)
/locus_tag="CGSHiEE_01640"
/note="tetramer interface [polypeptide binding]; other
site"
/db_xref="CDD:132920"
misc_feature order(306000..306002,306006..306011,306021..306023,
306072..306098,306105..306110,306114..306122,
306126..306131,306168..306170,306180..306182,
306189..306191,306201..306203,306210..306212,
306276..306281)
/locus_tag="CGSHiEE_01640"
/note="PYR/PP interface [polypeptide binding]; other site"
/db_xref="CDD:132920"
misc_feature 306090..306092
/locus_tag="CGSHiEE_01640"
/note="TPP binding site [chemical binding]; other site"
/db_xref="CDD:132920"
misc_feature 307041..307556
/locus_tag="CGSHiEE_01640"
/note="Thiamine pyrophosphate (TPP) family, SHCHC synthase
subfamily, TPP-binding module; composed of proteins
similar to Escherichia coli
2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid
(SHCHC) synthase (also called MenD). SHCHC synthase plays
a key...; Region: TPP_SHCHC_synthase; cd02009"
/db_xref="CDD:48172"
misc_feature order(307194..307196,307263..307274,307347..307349,
307353..307355)
/locus_tag="CGSHiEE_01640"
/note="TPP-binding site; other site"
/db_xref="CDD:48172"
gene 307686..308429
/locus_tag="CGSHiEE_01645"
/db_xref="GeneID:5224989"
CDS 307686..308429
/locus_tag="CGSHiEE_01645"
/note="catalyzes the hydrolysis of the thioester bond in
palmitoyl-CoA"
/codon_start=1
/transl_table=11
/product="acyl-CoA thioester hydrolase YfbB"
/protein_id="YP_001290192.1"
/db_xref="GI:148825439"
/db_xref="GeneID:5224989"
/translation="MINIIFLHGLLGTKNDWQKVIENLPHFNCIALDLPFHGQAKDLE
VTNFEETAEYLAQQIKSAVKNEPYFLVGYSLGGRIALYYALQAQVERFNLQGVILEGA
NLGLKTDEEKQARFQQDFAWAQRFIQELPEKVLNDWYQQPVFSHLTAEERLQLVEKRK
SNCGENIGKMLLATSLSKQPDFSEKVRLSSLPFFYFCGERDHKFQVLAKENQIDLVTI
PCAGHNSHLENSKYFSKKIENCILKIVRP"
misc_feature 307686..308417
/locus_tag="CGSHiEE_01645"
/note="2-succinyl-6-hydroxy-2,
4-cyclohexadiene-1-carboxylate synthase; Provisional;
Region: PRK11126"
/db_xref="CDD:182982"
misc_feature <307884..308186
/locus_tag="CGSHiEE_01645"
/note="Protein of unknown function (DUF726); Region:
DUF726; pfam05277"
/db_xref="CDD:191248"
gene 308485..309801
/locus_tag="CGSHiEE_01650"
/db_xref="GeneID:5224990"
CDS 308485..309801
/locus_tag="CGSHiEE_01650"
/note="COG0477 Permeases of the major facilitator
superfamily"
/codon_start=1
/transl_table=11
/product="acyl-CoA thioester hydrolase YfbB"
/protein_id="YP_001290193.1"
/db_xref="GI:148825440"
/db_xref="GeneID:5224990"
/translation="MSTQLRNNPMKVALASMVGTAIEFFDYYIYAAAAVLVFNTQFFH
SDDPLSNDLLSLSTLALAFFARPIGSALFGHFGDKIGRKKTLVASLVLMGGSTVVIGL
LPNYAQIGIWAPILLCVCRVGQGIGLGGEWGGAALVATENAPEGKRAWYGTFPQLGAP
IGLFVANGTFFLVSYLLGHNALVEWAWRIPFVSSILLVAVGLYVRLTLHESHVFVEAE
QKGKKLNAPVRVVFTKHLKPMIIGTFIMVATYSLFYIMTAFAQAYSRTAPKLSEAGYA
LGLGIPANTFTGFLLISAIVFGIFISISGFYADKIGRRKWLIWVTIAIGVLGLAMPLF
LENGTPVSVFAFLVIGMAIMGMTFGPMAALLPELFPTEVRYSGASLAYNLASIIGATI
AAMISLKINASFGVMGVGIYLAINALMTFLALLASKETKNVDLTEI"
misc_feature 308539..309747
/locus_tag="CGSHiEE_01650"
/note="metabolite-proton symporter; Region: 2A0106;
TIGR00883"
/db_xref="CDD:188094"
misc_feature 308668..309759
/locus_tag="CGSHiEE_01650"
/note="The Major Facilitator Superfamily (MFS) is a large
and diverse group of secondary transporters that includes
uniporters, symporters, and antiporters. MFS proteins
facilitate the transport across cytoplasmic or internal
membranes of a variety of...; Region: MFS; cd06174"
/db_xref="CDD:119392"
misc_feature order(308668..308673,308680..308682,308692..308697,
308701..308706,308866..308871,308878..308883,
308890..308895,308902..308904,308938..308943,
308950..308955,308971..308973,309232..309234,
309241..309246,309253..309258,309265..309267,
309307..309309,309319..309321,309331..309333,
309340..309342,309352..309354,309535..309537,
309544..309549,309556..309558,309568..309573,
309580..309582,309613..309618,309628..309633,
309640..309645,309652..309654)
/locus_tag="CGSHiEE_01650"
/note="putative substrate translocation pore; other site"
/db_xref="CDD:119392"
gene complement(310030..310788)
/locus_tag="CGSHiEE_01655"
/db_xref="GeneID:5224970"
CDS complement(310030..310788)
/locus_tag="CGSHiEE_01655"
/EC_number="2.4.2.3"
/note="catalyzes the reversible phosphorylytic cleavage of
uridine and deoxyuridine to uracil and ribose- or
deoxyribose-1-phosphate; involved in the pyrimidine
salvage pathway"
/codon_start=1
/transl_table=11
/product="uridine phosphorylase"
/protein_id="YP_001290194.1"
/db_xref="GI:148825441"
/db_xref="GeneID:5224970"
/translation="MSDVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLTS
TREFTSWLGYINGQPIVVCSTGIGGPSTSICVEELAQLGVRTFLRIGTTGAIQPHINV
GDVLITTAAVRLDGASRHFVPLEYPAVANFECTTALYNAAKAKGIEPYVGVTVSSDTF
YPGQERYDTYSGKVYRDYQGLLKQWQDLNVMNYEMESSTLFTMCSALGLRAGMVAGVI
VNRTQQEIPNEAAIKQTEEKAVSVVIAAAQALLS"
misc_feature complement(310036..310788)
/locus_tag="CGSHiEE_01655"
/note="uridine phosphorylase; Provisional; Region:
PRK11178"
/db_xref="CDD:183018"
misc_feature complement(310036..310788)
/locus_tag="CGSHiEE_01655"
/note="Uridine phosphorylase [Nucleotide transport and
metabolism]; Region: Udp; COG2820"
/db_xref="CDD:32648"
gene 311021..311587
/locus_tag="CGSHiEE_01660"
/db_xref="GeneID:5224971"
CDS 311021..311587
/locus_tag="CGSHiEE_01660"
/EC_number="2.4.2.3"
/note="COG2258 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="uridine phosphorylase"
/protein_id="YP_001290195.1"
/db_xref="GI:148825442"
/db_xref="GeneID:5224971"
/translation="MNAKILVIKVGQVETLTFSDGSQYESAIRKKVVPSVKIHSLGAE
GNDVGLKKHHGGVDKALFFMSADSFNELNALLNKDFSYMDTATYGENFVVSGLNEDNV
CIGDRYQIGSTILEVSQPRKPCERLSKNTENEDARDIIYQTGLSGWYVRIIETGTIKQ
KDELKLLARPYPQITIRHLNRLLSAPKK"
misc_feature 311027..311581
/locus_tag="CGSHiEE_01660"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG2258"
/db_xref="CDD:32439"
misc_feature 311141..311518
/locus_tag="CGSHiEE_01660"
/note="MOSC domain; Region: MOSC; pfam03473"
/db_xref="CDD:202655"
gene 311687..312169
/locus_tag="CGSHiEE_01665"
/db_xref="GeneID:5224972"
CDS 311687..312169
/locus_tag="CGSHiEE_01665"
/note="COG3012 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290196.1"
/db_xref="GI:148825443"
/db_xref="GeneID:5224972"
/translation="MSEISTALSEDCPCQSGHHYADCCGKFHLRQAFPETAEQLMRSR
YTAYVLKNIPYIVVTTVPSQQTLLEPRLLQEWADNTTWLGLEILKTESLTKTQSAVEF
KAIFQGEECEQAHQERSIFVKIEDRWYFVDPTVSLPTMKQPCVCGSGKKFKHCCGGFL
"
misc_feature 311708..312166
/locus_tag="CGSHiEE_01665"
/note="hypothetical protein; Provisional; Region:
PRK01752"
/db_xref="CDD:179332"
misc_feature 311711..311764
/locus_tag="CGSHiEE_01665"
/note="SEC-C motif; Region: SEC-C; pfam02810"
/db_xref="CDD:202406"
misc_feature 312104..312157
/locus_tag="CGSHiEE_01665"
/note="SEC-C motif; Region: SEC-C; pfam02810"
/db_xref="CDD:202406"
gene 312166..312975
/gene="rbn"
/locus_tag="CGSHiEE_01670"
/db_xref="GeneID:5224973"
CDS 312166..312975
/gene="rbn"
/locus_tag="CGSHiEE_01670"
/note="RNase BN; required for 3' maturation of certain
phage T4-encoded tRNAs; forms a dimer; specific for
immature tRNA substrates containing incorrect residues
within the universal CCA sequence; 3' to 5'
exoribonuclease"
/codon_start=1
/transl_table=11
/product="ribonuclease BN"
/protein_id="YP_001290197.1"
/db_xref="GI:148825444"
/db_xref="GeneID:5224973"
/translation="MISLKNFGLLFWKRFSENKLNQVAGALTYSTMLAMVPLVMVIFS
IFSAFPVFNEVTGELKEMIFTNFAPSASDMVGEYIDQFVSNSKKMSAVGIVSLIAVAL
MLINNIDRTLNSIWHNSQSRSPLSSFAIYWMILTLGPLIIGVSIGISSYIKIMFEQSE
HLSLGLKLLSFVPFLFTWFIFTLIYTVVPNKKVKIKHSAYGAFLAAIFFTLGKQAFTW
YIVTFPSYQLIYGAMATLPIMLLWIQISWLVVLVGAQLASTLDEIGEQIEQ"
misc_feature 312166..312954
/gene="rbn"
/locus_tag="CGSHiEE_01670"
/note="hypothetical protein; Reviewed; Region: PRK01637"
/db_xref="CDD:179313"
gene complement(312995..314650)
/gene="rbn"
/locus_tag="CGSHiEE_01675"
/db_xref="GeneID:5224974"
CDS complement(312995..314650)
/gene="rbn"
/locus_tag="CGSHiEE_01675"
/note="COG1368 Phosphoglycerol transferase and related
proteins, alkaline phosphatase superfamily"
/codon_start=1
/transl_table=11
/product="ribonuclease BN"
/protein_id="YP_001290198.1"
/db_xref="GI:148825445"
/db_xref="GeneID:5224974"
/translation="MIAYIFLALFTIAAVIFIVNSHYRWTYFFAITLFTFLFGGMLMV
SSQWQRALNFSSVLFVVLMLFHRLKIHYYKQPLLISDFFLVVDWRNWETLIHYKGALF
GVIGLLALLGYAILGFNDAESLGVLGNSIGALLFIVSFSLMWHYSKNPSAVQVWLDSL
PDDGRDVFLNLPMSCRGIFFKVPNFDGNSQNFIEKMTALSFDTNNLSETKPDIVVTLM
ESTLNPHQFAFSQQSIPPLSMFEPQNDTVFASPLRVHTFAGATWKSEFAFLAGVPSTD
FGALASGVFYSVVPHLQSGLVKNLKAQGYFCVALSPFTKGNYNAKSAYDHFGFDLMLQ
PQDLGYPAPISKNLWDISSEEMMKYTRMILEKQHPALENVDQPMFVYVLTMREHGPYE
LGMENIFNLQMPNLGAKSISALNDYTQRIVALNDAIEGMNNYLHERKKPFVLGYFGDH
QVAFDNTIPPKKGDYAQPDYVTQFVVRSNCSRQFKQEQKFLDLAFAGGILMNVAGLSA
EDEFMKANMTMCKLSHGKLEDSSDIQLLNDYRHYLYQTLAIAR"
misc_feature complement(312998..314650)
/gene="rbn"
/locus_tag="CGSHiEE_01675"
/note="Phosphoglycerol transferase and related proteins,
alkaline phosphatase superfamily [Cell envelope
biogenesis, outer membrane]; Region: MdoB; COG1368"
/db_xref="CDD:31559"
misc_feature complement(313112..314020)
/gene="rbn"
/locus_tag="CGSHiEE_01675"
/note="Sulfatase; Region: Sulfatase; cl10460"
/db_xref="CDD:213119"
gene complement(314773..314848)
/locus_tag="CGSHiEE_t09350"
/db_xref="GeneID:5542115"
tRNA complement(314773..314848)
/locus_tag="CGSHiEE_t09350"
/product="tRNA-Val"
/db_xref="GeneID:5542115"
gene complement(314901..314976)
/locus_tag="CGSHiEE_t09352"
/db_xref="GeneID:5542103"
tRNA complement(314901..314976)
/locus_tag="CGSHiEE_t09352"
/product="tRNA-Val"
/db_xref="GeneID:5542103"
gene complement(315035..315110)
/locus_tag="CGSHiEE_t09354"
/db_xref="GeneID:5542099"
tRNA complement(315035..315110)
/locus_tag="CGSHiEE_t09354"
/product="tRNA-Val"
/db_xref="GeneID:5542099"
gene complement(315154..315229)
/locus_tag="CGSHiEE_t09356"
/db_xref="GeneID:5542097"
tRNA complement(315154..315229)
/locus_tag="CGSHiEE_t09356"
/product="tRNA-Val"
/db_xref="GeneID:5542097"
gene 315400..316842
/gene="gltX"
/locus_tag="CGSHiEE_01680"
/db_xref="GeneID:5224975"
CDS 315400..316842
/gene="gltX"
/locus_tag="CGSHiEE_01680"
/EC_number="6.1.1.17"
/note="Charges one glutamine molecule and pairs it to its
corresponding RNA trinucleotide during protein
translation"
/codon_start=1
/transl_table=11
/product="glutamyl-tRNA synthetase"
/protein_id="YP_001290199.1"
/db_xref="GI:148825446"
/db_xref="GeneID:5224975"
/translation="MKLDAPFNLDPNVKVRTRFAPSPTGYLHVGGARTALYSWLYAKH
NNGEFVLRIEDTDLERSTPEATAAIIEGMEWLNLPWEHGPYYQTKRFDRYNQVIDEMI
EQGLAYRCYCTKEHLEELRHTQEQNKEKPRYDRHCLHDHNHSPDEPHVVRFKNPTEGS
VVFDDAVRGRIEISNSELDDLIIRRTDGSPTYNFCVVVDDWDMGITHVVRGEDHINNT
PRQINILKAIGAPIPTYAHVSMINGDDGQKLSKRHGAVSVMQYRDDGYLPEALINYLV
RLGWGHGDQEIFSREEMINYFELDHVSKSASAFNTEKLQWLNQHYIRELPPEYVAKHL
EWHYKDQGIDTSNGPALTDIVSMLAERCKTLKEMARSSRYFFEEFETFDEAAAKKHFK
GNAAEALTKVKEKLTALSSWDLHSTHEAIEQTAAELEVGMGKVGMPLRVAVTGSGQSP
SMDVTLVGIGRDRVLARIQRAIDFIHAQNA"
misc_feature 315439..316815
/gene="gltX"
/locus_tag="CGSHiEE_01680"
/note="glutamyl-tRNA synthetase; Reviewed; Region: gltX;
PRK01406"
/db_xref="CDD:179296"
misc_feature 315439..>315714
/gene="gltX"
/locus_tag="CGSHiEE_01680"
/note="catalytic core domain of discriminating
glutamyl-tRNA synthetase; Region: GluRS_core; cd00808"
/db_xref="CDD:173905"
misc_feature 315481..315492
/gene="gltX"
/locus_tag="CGSHiEE_01680"
/note="HIGH motif; other site"
/db_xref="CDD:173905"
misc_feature <315958..316371
/gene="gltX"
/locus_tag="CGSHiEE_01680"
/note="catalytic core domain of discriminating
glutamyl-tRNA synthetase; Region: GluRS_core; cd00808"
/db_xref="CDD:173905"
misc_feature order(315973..315975,315985..315987,316027..316032,
316036..316041,316114..316119,316141..316146)
/gene="gltX"
/locus_tag="CGSHiEE_01680"
/note="active site"
/db_xref="CDD:173905"
misc_feature 316141..316155
/gene="gltX"
/locus_tag="CGSHiEE_01680"
/note="KMSKS motif; other site"
/db_xref="CDD:173905"
gene 316923..316998
/locus_tag="CGSHiEE_t09358"
/db_xref="GeneID:5542113"
tRNA 316923..316998
/locus_tag="CGSHiEE_t09358"
/product="tRNA-Ala"
/db_xref="GeneID:5542113"
gene 317143..317859
/gene="rph"
/locus_tag="CGSHiEE_01685"
/db_xref="GeneID:5224960"
CDS 317143..317859
/gene="rph"
/locus_tag="CGSHiEE_01685"
/EC_number="2.7.7.56"
/note="RNase PH; tRNA nucleotidyltransferase; forms
hexamers in Bacillus subtilis; phosphoroltic 3'-5'
exoribonuclease; involved in maturation of tRNA precursors
and removes terminal nucleotides near CCA acceptor arms of
mature tRNAs"
/codon_start=1
/transl_table=11
/product="ribonuclease PH"
/protein_id="YP_001290200.1"
/db_xref="GI:148825447"
/db_xref="GeneID:5224960"
/translation="MRPNNRENNQPRQIKITRNYTKHAEGSVLVEFGDTKVLCTATVE
DAVPRFLKGQGQGWVTAEYGMLPRSTHSRMQREAAKGKQGGRTMEIQRLIARSLRAMV
DLKALGERAITLDCDVIQADGGTRTASITGAAVALCDAINSLIENGTLKTNPIKGLVS
AISVGIVDGQAVCDLEYVEDSAAETDMNVVMMEDGRMIEVQGTAEGEPFSHEELLTLL
DLAKQGCNQIFIAQREALGL"
misc_feature 317182..317853
/gene="rph"
/locus_tag="CGSHiEE_01685"
/note="ribonuclease PH; Reviewed; Region: rph; PRK00173"
/db_xref="CDD:178914"
misc_feature 317182..317850
/gene="rph"
/locus_tag="CGSHiEE_01685"
/note="Ribonuclease PH; Region: RNase_PH_bact; cd11362"
/db_xref="CDD:206767"
misc_feature order(317200..317214,317242..317244,317248..317250,
317254..317256,317260..317262,317266..317268,
317326..317328,317332..317334,317338..317355,
317359..317361,317368..317373,317395..317400,
317404..317409,317416..317418,317428..317430,
317437..317439,317479..317481,317485..317487,
317491..317493,317497..317505,317728..317742,
317746..317748,317752..317769,317773..317775,
317782..317787,317794..317799,317806..317808)
/gene="rph"
/locus_tag="CGSHiEE_01685"
/note="hexamer interface [polypeptide binding]; other
site"
/db_xref="CDD:206767"
misc_feature order(317335..317337,317398..317400,317503..317520,
317680..317682,317698..317700)
/gene="rph"
/locus_tag="CGSHiEE_01685"
/note="active site"
/db_xref="CDD:206767"
gene 317883..318524
/gene="pyrE"
/locus_tag="CGSHiEE_01690"
/db_xref="GeneID:5224961"
CDS 317883..318524
/gene="pyrE"
/locus_tag="CGSHiEE_01690"
/EC_number="2.4.2.10"
/note="involved in fifth step of pyrimidine biosynthesis;
converts orotidine 5'-phosphate and diphosphate to orotate
and 5-phospho-alpha-D-ribose 1-diphosphate"
/codon_start=1
/transl_table=11
/product="orotate phosphoribosyltransferase"
/protein_id="YP_001290201.1"
/db_xref="GI:148825448"
/db_xref="GeneID:5224961"
/translation="MEQYKRDFIEFALSRNVLKFGEFTLKSGRKSPYFFNAGLFNTGA
DLARLGEFYAAAIQASAVDFDVVFGPAYKGIPIGTSVSVALFNRYGIDKPVCFNRKEV
KDHGEGGNLIGSPLQGKILLVDDVITAGTAIRESMELISANQAELAAVLIALNRKERG
KGELSAIQEVERDYQCQVLSIIDLDDLMQFIEQDPRYSSHLPEMRAYRAEFGV"
misc_feature 318027..318380
/gene="pyrE"
/locus_tag="CGSHiEE_01690"
/note="Phosphoribosyl transferase (PRT)-type I domain;
Region: PRTases_typeI; cd06223"
/db_xref="CDD:206754"
misc_feature order(318093..318095,318099..318101,318252..318260,
318264..318278,318348..318350)
/gene="pyrE"
/locus_tag="CGSHiEE_01690"
/note="active site"
/db_xref="CDD:206754"
gene 318603..319469
/gene="djlA"
/locus_tag="CGSHiEE_01695"
/db_xref="GeneID:5224962"
CDS 318603..319469
/gene="djlA"
/locus_tag="CGSHiEE_01695"
/note="functions as a co-chaperone with DnaK; involved in
regulation of colanic acid capsule; inner membrane
protein; dimerized via transmembrane domain; J-like domain
is cytoplasmic and can functionally substitute for DnaJ;
stimulates synthesis of colanic acid mucoid capsule
through the RcsB/C signal transduction system"
/codon_start=1
/transl_table=11
/product="Dna-J like membrane chaperone protein"
/protein_id="YP_001290202.1"
/db_xref="GI:148825449"
/db_xref="GeneID:5224962"
/translation="MGFIGKIIGVFLGWKVGGFFGAIAGLILGSIADKKLYELGSVSS
SFFKKKTTRQDLFMQTTFAVLGHLSKSKGRVTEEDIQLANQLMIQLKLDDAGRKLAQD
AFRRGKESDFPIRQVIREFRIGCGQRADLLRMFLQVQVQAAFADSELHENEKEVLYVI
AEELGLSRMQFEQMIAMEMAARAFTQGGFYQQYQQGAYQGGYQYQQQNSGGYQHASGP
TLNDAYKVLGVTESDEQSTVKRAYRRLMNEHHPDKLVAKGLPPEMMEMAKEKTQQIQA
AYDLICKAKGWK"
misc_feature 318603..319466
/gene="djlA"
/locus_tag="CGSHiEE_01695"
/note="Dna-J like membrane chaperone protein; Provisional;
Region: djlA; PRK09430"
/db_xref="CDD:181850"
misc_feature 318780..319097
/gene="djlA"
/locus_tag="CGSHiEE_01695"
/note="N-terminal tellurium resistance protein terB-like
domain of heat shock DnaJ-like proteins; Region:
terB_like_DjlA; cd07316"
/db_xref="CDD:143585"
misc_feature order(318816..318818,318837..318839,319038..319040,
319059..319061)
/gene="djlA"
/locus_tag="CGSHiEE_01695"
/note="putative metal binding site [ion binding]; other
site"
/db_xref="CDD:143585"
misc_feature 319266..319439
/gene="djlA"
/locus_tag="CGSHiEE_01695"
/note="DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock
protein 40) proteins are highly conserved and play crucial
roles in protein translation, folding, unfolding,
translocation, and degradation. They act primarily by
stimulating the ATPase activity of Hsp70s; Region: DnaJ;
cd06257"
/db_xref="CDD:99751"
misc_feature order(319350..319358,319404..319406,319413..319418,
319425..319430)
/gene="djlA"
/locus_tag="CGSHiEE_01695"
/note="HSP70 interaction site [polypeptide binding]; other
site"
/db_xref="CDD:99751"
gene 319469..320401
/gene="djlA"
/locus_tag="CGSHiEE_01700"
/db_xref="GeneID:5224963"
CDS 319469..320401
/gene="djlA"
/locus_tag="CGSHiEE_01700"
/note="COG0042 tRNA-dihydrouridine synthase"
/codon_start=1
/transl_table=11
/product="DnaJ-like membrane chaperone protein"
/protein_id="YP_001290203.1"
/db_xref="GI:148825450"
/db_xref="GeneID:5224963"
/translation="MRVILAPMQGVLDPFVRELLTEVNDYDLCITEFVRVVDQLLPEK
VFYRLCPELKNQGFTSSSTPVRVQLLGQHPECLAENAIRAIELGSHGIDLNCGCPSKT
VNGSNGGAALLKQPELIYRATQALRRAVPSEFPVSVKVRLGWDDISQAFEIADAVEQG
GATEITVHGRTKSDGYRADRINWKKIGKVRERLSIPVIANGEIWHWQDGQDCLSQTGC
QDLMVGRGALNIPNLSHVLKSNAEKMPWREIQKILQKYAKVENEYDSGFYHVARIKQW
LRYLNKEYDEANQEFDKIKTCQNAEDLKLRLNDK"
misc_feature 319469..320377
/gene="djlA"
/locus_tag="CGSHiEE_01700"
/note="tRNA-dihydrouridine synthase C; Provisional;
Region: PRK10550"
/db_xref="CDD:182540"
misc_feature 319472..320167
/gene="djlA"
/locus_tag="CGSHiEE_01700"
/note="Dihydrouridine synthase-like (DUS-like) FMN-binding
domain. Members of this family catalyze the reduction of
the 5,6-double bond of a uridine residue on tRNA.
Dihydrouridine modification of tRNA is widely observed in
prokaryotes and eukaryotes, and also...; Region:
DUS_like_FMN; cd02801"
/db_xref="CDD:73368"
misc_feature order(319484..319492,319565..319567,319670..319672,
319751..319753,319883..319885,319970..319972,
320066..320068,320072..320074,320138..320143)
/gene="djlA"
/locus_tag="CGSHiEE_01700"
/note="FMN binding site [chemical binding]; other site"
/db_xref="CDD:73368"
misc_feature order(319670..319672,319760..319765,319883..319885,
319889..319891,319967..319972,319976..319981,
320069..320074,320141..320143)
/gene="djlA"
/locus_tag="CGSHiEE_01700"
/note="active site"
/db_xref="CDD:73368"
misc_feature order(319760..319762,319889..319891,319970..319972,
319976..319978)
/gene="djlA"
/locus_tag="CGSHiEE_01700"
/note="catalytic residues [active]"
/db_xref="CDD:73368"
misc_feature order(319763..319765,319883..319885,319967..319969,
319979..319981,320069..320074)
/gene="djlA"
/locus_tag="CGSHiEE_01700"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:73368"
gene complement(320441..321286)
/locus_tag="CGSHiEE_01705"
/db_xref="GeneID:5224964"
CDS complement(320441..321286)
/locus_tag="CGSHiEE_01705"
/note="binds with the catalytic core of RNA polymerase to
produce the holoenzyme; this sigma factor is responsible
for the expression of heat shock promoters"
/codon_start=1
/transl_table=11
/product="RNA polymerase factor sigma-32"
/protein_id="YP_001290204.1"
/db_xref="GI:148825451"
/db_xref="GeneID:5224964"
/translation="MDKETQMMLVPQGSIEGYIRAANEYPMLTAEEEKELAERLYYHE
DLDAAKKLILSHLRFVIHVARGYSGYGLPQADLIQEGNIGLMKAVKRFNPEVGVRLVS
FAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNENEVDMVANEL
GVSKEDVIEMESRMSGADVGFDLPTDDAETETYSPSLYLEDKSSNFAAELENENFESQ
ATEQLGVALQSLDARSQDIIKARWLDDNKATLHDLAAKYNVSAERIRQLETNALKKLK
SAVSF"
misc_feature complement(320450..321286)
/locus_tag="CGSHiEE_01705"
/note="RNA polymerase factor sigma-32; Reviewed; Region:
PRK06596"
/db_xref="CDD:180635"
misc_feature complement(<321170..321235)
/locus_tag="CGSHiEE_01705"
/note="Sigma-70 factor, region 1.2; Region: Sigma70_r1_2;
pfam00140"
/db_xref="CDD:201030"
misc_feature complement(320921..321133)
/locus_tag="CGSHiEE_01705"
/note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542"
/db_xref="CDD:146937"
misc_feature complement(320459..320611)
/locus_tag="CGSHiEE_01705"
/note="Sigma70, region (SR) 4 refers to the most
C-terminal of four conserved domains found in Escherichia
coli (Ec) sigma70, the main housekeeping sigma, and
related sigma-factors (SFs). A SF is a dissociable subunit
of RNA polymerase, it directs bacterial or...; Region:
Sigma70_r4; cd06171"
/db_xref="CDD:100119"
misc_feature complement(order(320471..320473,320477..320482,
320486..320494,320498..320503,320507..320509,
320537..320542,320564..320566,320594..320596))
/locus_tag="CGSHiEE_01705"
/note="DNA binding residues [nucleotide binding]"
/db_xref="CDD:100119"
gene complement(321424..321735)
/locus_tag="CGSHiEE_01710"
/db_xref="GeneID:5224807"
CDS complement(321424..321735)
/locus_tag="CGSHiEE_01710"
/note="COG4390 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="RNA polymerase factor sigma-32"
/protein_id="YP_001290205.1"
/db_xref="GI:148825452"
/db_xref="GeneID:5224807"
/translation="MNFKEILETLPNIDHLTGLNVMNGETIIHNIPAIQGKLGSLRLY
NALAEKFNGKLNRTSAQQGVEWFAEHVEDAKANPGKHPNIDLLFKVIDENLNLTLIPL
C"
misc_feature complement(321430..321729)
/locus_tag="CGSHiEE_01710"
/note="Uncharacterized protein conserved in bacteria
(DUF2322); Region: DUF2322; pfam10084"
/db_xref="CDD:150726"
gene complement(321759..322784)
/gene="murB"
/locus_tag="CGSHiEE_01715"
/db_xref="GeneID:5224808"
CDS complement(321759..322784)
/gene="murB"
/locus_tag="CGSHiEE_01715"
/EC_number="1.1.1.158"
/note="catalyzes the reduction of UDP-N-acetylglucosamine
enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan
biosynthesis"
/codon_start=1
/transl_table=11
/product="UDP-N-acetylenolpyruvoylglucosamine reductase"
/protein_id="YP_001290206.1"
/db_xref="GI:148825453"
/db_xref="GeneID:5224808"
/translation="MQNLQPFHTFHIQSNAREIIEAHSIEQLQQVWTYSKSENLPVLF
LGQGSNVLFLDDFNGVVVLNRLMGITHEQDANFHYLHVNGGENWHKLVEWSINNGIYG
LENLALIPGCAGSAPIQNIGAYGVEFKDVCDYVEVLNLNTNETFRLDTEQCEFGYRES
IFKHRYQQGYVITAIGLKLKKDWQPILKYGSLVEFDPKTVTAKQIFDEVCHIRQSKLP
DPNEVGNAGSFFKNPVVSSEHFEKIKKHHENLPHFPQADGSVKLAAGWLIDQCNLKGF
QIGGAAVHKKQALVLINKSGATGQDVVKLAHHVRQTVAEKFGVYLQPEVRFISATGEV
NSEQIIT"
misc_feature complement(321801..322784)
/gene="murB"
/locus_tag="CGSHiEE_01715"
/note="UDP-N-acetylenolpyruvoylglucosamine reductase;
Provisional; Region: murB; PRK00046"
/db_xref="CDD:178820"
misc_feature complement(322368..322730)
/gene="murB"
/locus_tag="CGSHiEE_01715"
/note="FAD binding domain; Region: FAD_binding_4;
pfam01565"
/db_xref="CDD:201863"
misc_feature complement(321798..322178)
/gene="murB"
/locus_tag="CGSHiEE_01715"
/note="UDP-N-acetylenolpyruvoylglucosamine reductase,
C-terminal domain; Region: MurB_C; pfam02873"
/db_xref="CDD:111727"
gene complement(322794..324497)
/locus_tag="CGSHiEE_01720"
/db_xref="GeneID:5224795"
CDS complement(322794..324497)
/locus_tag="CGSHiEE_01720"
/note="COG3850 Signal transduction histidine kinase,
nitrate/nitrite-specific"
/codon_start=1
/transl_table=11
/product="nitrate/nitrite sensor protein NarQ"
/protein_id="YP_001290207.1"
/db_xref="GI:148825454"
/db_xref="GeneID:5224795"
/translation="MYTKGSVSTRIAKYLFIILIVAGVISSLSLAIMSSNKYDAEAIN
ISGSLRMQSYRLLYEMQEQPESVETNLRRYHISLHSSALLEVQNQFFTPNVLKHSYQN
ILQRWTNMEKYARQQDVKNYSKQLTNYVADVDYFVFELQRFSEQKWILGVSVLGFAML
LILLMVSYVIWYTNREVVKPLHLMTKASMQVQMRQFNHIPLDTRKQNELGTLARVFTQ
MSTELGQLYSRLEEAVNEKTQKLRQTNRTLSTLYQSAQLLNTNTINDKILNQVLHYIF
ISDHLNFVKVEVMGAEHWDITLGKQDANNELQIETLSVDNEELGVLSWQAGLPCPDPR
IMQNLAQMLARALYFHKNLRQKEQILLMEERSIIARELHDSLAQVLSFLQIQLTLLKH
NLKKEDEQSKEKSLAIIANFEQALSGGYAQLRELLATFRLTIQEANLQLALGQVIDSL
RSQTTMQMNVNCQLPSQSLNPQQLVHVLQIVREATTNAIKHSQGTVIEISARINAEGE
YEILVEDDGVGIPNLEEPEGHYGLNIMAERCRQLNAQLHIHRREQGGTQVKITLPDTL
Y"
misc_feature complement(322809..324497)
/locus_tag="CGSHiEE_01720"
/note="nitrate/nitrite sensor protein NarQ; Provisional;
Region: PRK10935"
/db_xref="CDD:182850"
misc_feature complement(324096..324413)
/locus_tag="CGSHiEE_01720"
/note="Type IV pili methyl-accepting chemotaxis transducer
N-term; Region: PilJ; pfam13675"
/db_xref="CDD:205851"
misc_feature complement(323829..324035)
/locus_tag="CGSHiEE_01720"
/note="HAMP domain; Region: HAMP; pfam00672"
/db_xref="CDD:189662"
misc_feature complement(order(323829..323834,323841..323846,
323850..323855,323862..323867,323871..323876,
323925..323927,323931..323936,323943..323948,
323952..323957,323964..323969))
/locus_tag="CGSHiEE_01720"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:100122"
misc_feature complement(323205..323408)
/locus_tag="CGSHiEE_01720"
/note="Histidine kinase; Region: HisKA_3; pfam07730"
/db_xref="CDD:203743"
misc_feature complement(322812..323063)
/locus_tag="CGSHiEE_01720"
/note="Histidine kinase-like ATPases; This family includes
several ATP-binding proteins for example: histidine
kinase, DNA gyrase B, topoisomerases, heat shock protein
HSP90, phytochrome-like ATPases and DNA mismatch repair
proteins; Region: HATPase_c; cd00075"
/db_xref="CDD:28956"
misc_feature complement(order(322824..322826,322830..322835,
322848..322850,322854..322856,322902..322910,
322938..322943,322947..322949,322953..322955,
322959..322961,323028..323030,323037..323039,
323049..323051))
/locus_tag="CGSHiEE_01720"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:28956"
misc_feature complement(323037..323039)
/locus_tag="CGSHiEE_01720"
/note="Mg2+ binding site [ion binding]; other site"
/db_xref="CDD:28956"
misc_feature complement(order(322905..322907,322941..322943,
322947..322949))
/locus_tag="CGSHiEE_01720"
/note="G-X-G motif; other site"
/db_xref="CDD:28956"
gene complement(324539..325138)
/locus_tag="CGSHiEE_01725"
/db_xref="GeneID:5224796"
CDS complement(324539..325138)
/locus_tag="CGSHiEE_01725"
/note="involved in acylation of glycerol-3-phosphate to
form 1-acyl-glycerol-3 phosphate for use in phospholipid
biosynthesis; functions with PlsX"
/codon_start=1
/transl_table=11
/product="putative glycerol-3-phosphate acyltransferase
PlsY"
/protein_id="YP_001290208.1"
/db_xref="GI:148825455"
/db_xref="GeneID:5224796"
/translation="MSLFALFYMLFAYLLGSVSSAILICRIAGLPDPRQNGSHNPGAT
NVLRIGNRKSALAVLIFDMLKGMIPVWAGYYLGLTQFELGMVALGACLGHIFPIFFQF
KGGKGVATAFGAIAPISWAVAGSMFGTWIFVFLVSGYSSLSAVISALLVPFYVWWFKP
EFTFPVALVCCLLIYRHHDNIQRLWRGQEDKVWAKFKKK"
misc_feature complement(324551..325093)
/locus_tag="CGSHiEE_01725"
/note="putative glycerol-3-phosphate acyltransferase PlsY;
Provisional; Region: PRK00220"
/db_xref="CDD:178934"
gene 325221..325577
/locus_tag="CGSHiEE_01730"
/db_xref="GeneID:5224797"
CDS 325221..325577
/locus_tag="CGSHiEE_01730"
/note="COG1539 Dihydroneopterin aldolase"
/codon_start=1
/transl_table=11
/product="dihydroneopterin aldolase"
/protein_id="YP_001290209.1"
/db_xref="GI:148825456"
/db_xref="GeneID:5224797"
/translation="MDRVFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCKQAAET
DDVVYCLNYAEVSQAIIDYVESKPFLLIERVAYEVADLLESRYQLQGLKIKLSKPKAV
AQARNVGVLIVRGCLK"
misc_feature 325221..325565
/locus_tag="CGSHiEE_01730"
/note="Dihydroneopterin aldolase (DHNA) and
7,8-dihydroneopterin triphosphate epimerase domain
(DHNTPE); these enzymes have been designated folB and
folX, respectively. Folate derivatives are essential
cofactors in the biosynthesis of purines, pyrimidines,
and...; Region: DHNA_DHNTPE; cd00534"
/db_xref="CDD:29762"
misc_feature order(325224..325256,325272..325298,325518..325523,
325530..325556)
/locus_tag="CGSHiEE_01730"
/note="homooctamer interface [polypeptide binding]; other
site"
/db_xref="CDD:29762"
misc_feature order(325266..325274,325281..325283,325428..325439,
325512..325514,325548..325550)
/locus_tag="CGSHiEE_01730"
/note="active site"
/db_xref="CDD:29762"
gene complement(325673..328411)
/locus_tag="CGSHiEE_01735"
/db_xref="GeneID:5224798"
CDS complement(325673..328411)
/locus_tag="CGSHiEE_01735"
/note="COG3210 Large exoproteins involved in heme
utilization or adhesion"
/codon_start=1
/transl_table=11
/product="heme/hemopexin-binding protein A"
/protein_id="YP_001290210.1"
/db_xref="GI:148825457"
/db_xref="GeneID:5224798"
/translation="MYKLNVISLIILTTYTGATYASTQDLPQEGLPQHHETVFGNVTI
DKTTDKMTITQSSPTTQINWKSFDIGQNKEVKFEQPDANSVAYNRVTGGNASQIQGKL
TANGKVYLANPNGVIITQGAQINVAGLFATTKDLEQISENGNGNGNKFTRKAKEGKVL
TEGQVINEGKIEAKDFVVLNGDEIINKGKIDATNGKVYLSSDYNFTFTLLPDSGISVA
LEDNTVQGIVKNEGSIKAGEITLSAKGRKQALDSLVVNNGVLEATKVSNKNGKVVLSA
DEIKLDDKSNIKGQIVSFVADVTSNNEPKNKIKITSQTGSKVTSPEINFKGKSVNING
NFGREDNNDYYKDEFKTLKTEVNIDVPDNENIRIADQDKDNTGTGSFIQTGALSSLLA
NNGKVNLKGNEVNISGRIHINSFKGTDSLLKLTNKGHIKINHADINSKGRLFFITSLQ
NEKDFQSNITITDSKINLGNGAMGLGRSVNESDYDNRYQKTEGSQRKKFNVNMSNVEF
NQVDDVILAGGFEKVNLDKIVATGQTNFYIDGGVSRNGRKYEYGVLDLDKRTQLSELD
QGRRRWGYYYDLELDMNRAYLYRFDLFAAKNTKRSTIKDTEINISNSNINLKNGFVHL
LAEKIKLDNSKIDITFDKDNSQDTLAQTNRLGMNGKVSMINSHIKIVGDEKEGISPTG
TYATMFLIGELIGEKSSIFVKSHQGYTFKTDGDTKIAGKNSKEDLKITAINTGGRAAE
EVLINGALGSADNDANIANMAFTIGDSANTKTTIENADITALAPNGGTAYLSSKDVEI
EVKPNSNFTFFELPREKNFNQTKINGDSTKLSERGFARLYDKINGVRASNLSAEQLNV
TDASEKIINTKLVSSLDVEKLVSVAVCDAGKGCEEQQFGDKGNNTKVSVGELETEQ"
misc_feature complement(325694..328237)
/locus_tag="CGSHiEE_01735"
/note="Large exoproteins involved in heme utilization or
adhesion [Intracellular trafficking and secretion];
Region: FhaB; COG3210"
/db_xref="CDD:33023"
misc_feature complement(328004..328231)
/locus_tag="CGSHiEE_01735"
/note="filamentous hemagglutinin family N-terminal domain;
Region: adhes_NPXG; TIGR01901"
/db_xref="CDD:130956"
gene complement(328423..330111)
/locus_tag="CGSHiEE_01740"
/db_xref="GeneID:5224799"
CDS complement(328423..330111)
/locus_tag="CGSHiEE_01740"
/note="COG2831 Hemolysin activation/secretion protein"
/codon_start=1
/transl_table=11
/product="heme/hemopexin-binding protein B"
/protein_id="YP_001290211.1"
/db_xref="GI:148825458"
/db_xref="GeneID:5224799"
/translation="MRPRYSVIASAVSLGFVLSKSVMALVPNAGSLNRELEQRQIQPE
AKPGGELFNQAAKSPYTAQYKQELKFPLTQVQILDRNNQEVAADELAHILKNYVGKEV
SLSDLSNLANEISEFYRNNNYLVAKAILPPQEIEQGTVKILLLKGNVGEIRLQNHSAL
SNKFVSRLSNTTVNTSEFILKDELEKFALTINDVPGVNAGLQLSAGKKVGEANLLIKI
NDAKRFSGYVSVDNQGNKYTGRYRLAAGTKVNNLTGWGDELKLDLLSSNQANLKNARI
DYSSLIDGYSTRFGVTANYLDYKLGGNFKSLQSQGHSHTLGAYLLHPTIRTPNFRLST
KVSFNHQNLTDKQQAVNVKQKRKINSLTAGIDGSWNLIKDGTTYFSLSTLFGNLANQT
SEKQHNAVENFQPQSHFTVYNYRLSHEQILPKSFAFNIGINGQFADKTLESSQKMLLG
GLSGVRGHQAGAASVDEGHLIQTEFKHYLPVFSQSVLVSSLFYDYGLGKSYKNSQFLA
PGVKNNVKLQSVGAGLSLSDAGSYAINVSVAKPLDNNIDNTDKHQFWLSMIKTF"
misc_feature complement(328426..330081)
/locus_tag="CGSHiEE_01740"
/note="Hemolysin activation/secretion protein
[Intracellular trafficking and secretion]; Region: FhaC;
COG2831"
/db_xref="CDD:32659"
misc_feature complement(329671..329904)
/locus_tag="CGSHiEE_01740"
/note="POTRA domain, ShlB-type; Region: POTRA_2;
pfam08479"
/db_xref="CDD:117056"
misc_feature complement(328426..329361)
/locus_tag="CGSHiEE_01740"
/note="Surface antigen; Region: Bac_surface_Ag; cl03097"
/db_xref="CDD:155280"
gene complement(330193..332355)
/locus_tag="CGSHiEE_01745"
/db_xref="GeneID:5224779"
CDS complement(330193..332355)
/locus_tag="CGSHiEE_01745"
/note="COG1629 Outer membrane receptor proteins, mostly Fe
transport"
/codon_start=1
/transl_table=11
/product="heme-hemopexin utilization protein C"
/protein_id="YP_001290212.1"
/db_xref="GI:148825459"
/db_xref="GeneID:5224779"
/translation="MRFSKLSLAITTTLVTANALAQSVELDSINVIATRDPSRFAYTP
EKQSKDSLLSKQATSVAAALEDIPNVDIRGGSRSIAQKPNIRGLSDNRVVQVIDGVRQ
NFDLAHRGSYFLPMSLIQEIEVIKGPSSSLWGSGALGGVVAMRTPNALDLLKNNDKFG
VKIRQGYQTANNLSERDASVFAANDKFDVLISAFYNNADNLRIGKGNKLNNTAYKQFG
GLSKFGWQINDANRVELSHRETRFKQTAPGNNEVENELTNEKIIDQINEFHGLNDSFP
PRKKPSTSETLKFYSGVKTRFGSVSYLSDQQIPDQSTVFNYYLTPDNPYLNTHIALYN
NKTIEKEQRKVSGVKDQTKLTTRGINLRNSSELSHISFVYGVDYMRDKIRTERGTNDK
DAKFRAEPYNANSNTTGVYLIAHIPLFGEKLLVSPSVRYDHYDTSSKTVKYKDNHLSP
ATKLTWIVTNWLDFTAKYNEAFRAPSMQERFVSGAHFGAETLGLNQVNRFVANPNLRP
ETAKNKEITANLHFDSLFKQGDKFKIEATYFRNDVKDFINLKIFNDANTSTSTSTSAN
GAFLPKNSQYQNITNARLSGIELQAQYQTERLTLFTNYGSTKGRDKDSGEALSNIAAS
KIGVGADYALVKDKFTVGATITHYAAQHRVPKDHAVTYPSYILTDLRATYAPLKGEWK
NLRLDFALENLFDRKYQPAFSLIEGTGRNAKISAVYSF"
misc_feature complement(330196..332280)
/locus_tag="CGSHiEE_01745"
/note="TonB-dependent heme/hemoglobin receptor family
protein; Region: TonB-hemin; TIGR01785"
/db_xref="CDD:162536"
misc_feature complement(330196..332214)
/locus_tag="CGSHiEE_01745"
/note="TonB dependent/Ligand-Gated channels are created by
a monomeric 22 strand (22,24) anti-parallel beta-barrel.
Ligands apparently bind to the large extracellular loops.
The N-terminal 150-200 residues form a plug from the
periplasmic end of barrel; Region: ligand_gated_channel;
cd01347"
/db_xref="CDD:73259"
misc_feature complement(order(331918..331944,331978..332010,
332050..332073,332092..332109,332143..332172,
332200..332214))
/locus_tag="CGSHiEE_01745"
/note="N-terminal plug; other site"
/db_xref="CDD:73259"
misc_feature complement(order(331339..331341,331435..331437))
/locus_tag="CGSHiEE_01745"
/note="ligand-binding site [chemical binding]; other site"
/db_xref="CDD:73259"
misc_feature complement(332678..333720)
/note="potential frameshift: common BLAST hit:
gi|16272219|ref|NP_438430.1| lipopolysaccharide
biosynthesis protein [Haemophilus influenzae Rd]"
gene 333797..334522
/locus_tag="CGSHiEE_01760"
/db_xref="GeneID:5224780"
CDS 333797..334522
/locus_tag="CGSHiEE_01760"
/note="catalyzes the phosphorylation of
3-deoxy-D-manno-octulosonic acid at the 4-OH position"
/codon_start=1
/transl_table=11
/product="3-deoxy-D-manno-octulosonic-acid kinase"
/protein_id="YP_001290213.1"
/db_xref="GI:148825460"
/db_xref="GeneID:5224780"
/translation="MQQFQQDNQYFIFNFDRTFEQATEFFQAEFWQKQERVIGSAKGR
GTTYFLQTEDWFGVNCALRHYYRGGLWGKLNKDRYRFSALETTRSFAEFHLLQRLYEA
GLPVPKPIAARIQKGKLGICYQADILTEKIENAQDLTALLQTQTLPKETWRQIGRLIR
KLHDLQICHTDLNAHNILLQQAEQGQKCWLLDFDKCGEKSGDFWKVQNLNRLKRSFEK
EVGRMNIQFTEQNWADLMAAYHQ"
misc_feature 333797..334519
/locus_tag="CGSHiEE_01760"
/note="3-deoxy-D-manno-octulosonic-acid kinase; Reviewed;
Region: PRK01723"
/db_xref="CDD:179326"
misc_feature order(334115..334117,334181..334192,334208..334210,
334322..334324,334328..334330,334367..334372)
/locus_tag="CGSHiEE_01760"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:88273"
gene 334534..335121
/locus_tag="CGSHiEE_01765"
/db_xref="GeneID:5224781"
CDS 334534..335121
/locus_tag="CGSHiEE_01765"
/note="HAM1-like protein; Rec-dependent growth; RgdB;
yggV; it is suspected that this protein functions to
remove misincorporated bases such as xanthine or
hypoxanthine"
/codon_start=1
/transl_table=11
/product="putative deoxyribonucleotide triphosphate
pyrophosphatase"
/protein_id="YP_001290214.1"
/db_xref="GI:148825461"
/db_xref="GeneID:5224781"
/translation="MKQKIVLATGNKGKVKEMADVLSDFGFEVIAQTDLGIESPEETG
LTFVENALLKARYASEKSGLPAIADDSGLVVSALNGAPGLYSARYAGEEGNDAKNREK
LLAELAHIAQDQRQAKFVSCIVFLQHPTDPSPIIAEGECCGVIGFEEKGENGFGYDSL
FFSPEQGCTFAELETAEKKKISHRAKALSVLKNKL"
misc_feature 334546..335109
/locus_tag="CGSHiEE_01765"
/note="NTPase/HAM1. This family consists of the HAM1
protein and pyrophosphate-releasing xanthosine/ inosine
triphosphatase. HAM1 protects the cell against mutagenesis
by the base analog 6-N-hydroxylaminopurine (HAP) in E.
Coli and S. cerevisiae. A...; Region: HAM1; cd00515"
/db_xref="CDD:29953"
misc_feature order(334564..334566,334570..334575,334582..334584,
334744..334752,334789..334794,334888..334890,
334996..334998,335002..335007,335080..335085)
/locus_tag="CGSHiEE_01765"
/note="active site"
/db_xref="CDD:29953"
misc_feature order(334657..334665,334765..334770,334777..334779,
334786..334788,334795..334797)
/locus_tag="CGSHiEE_01765"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:29953"
gene 335179..336018
/locus_tag="CGSHiEE_01770"
/db_xref="GeneID:5224782"
CDS 335179..336018
/locus_tag="CGSHiEE_01770"
/codon_start=1
/transl_table=11
/product="UDP-galactose--lipooligosaccharide
galactosyltransferase"
/protein_id="YP_001290215.1"
/db_xref="GI:148825462"
/db_xref="GeneID:5224782"
/translation="MLIRDNFITDRQTDRQTDRINIIFSSDNYYATYLAVSIFSIIKN
TPEKINFYILDMKINQENKTIINNLASSYSCKVFFLPVCEADFQNFPKTIDYISLATY
ARLNLTKYIKNIEKAIYIDVDTLTNSSLQELWDIDITNYYLAACRDTFIDVKNEAYKK
SIGLEGYSYFNAGILLINLNKWKEENIFQKSINWMNKYNNVMKYQDQDILNGICKGKV
KFINNRFNFTPTDRGLIKKKNLLHVKMPIVISHYCGPYKFWHKKMQSLKLSYRKFTFK
RNG"
misc_feature 335236..335961
/locus_tag="CGSHiEE_01770"
/note="A4GalT_like proteins catalyze the addition of
galactose or glucose residues to the lipooligosaccharide
(LOS) or lipopolysaccharide (LPS) of the bacterial cell
surface; Region: GT8_A4GalT_like; cd04194"
/db_xref="CDD:133037"
misc_feature 335239..335958
/locus_tag="CGSHiEE_01770"
/note="Glycosyl transferase family 8; Region:
Glyco_transf_8; pfam01501"
/db_xref="CDD:201828"
misc_feature order(335251..335259,335263..335268,335479..335481,
335488..335490,335539..335547,335620..335622,
335689..335697,335794..335799,335863..335865,
335929..335931,335935..335940,335947..335949)
/locus_tag="CGSHiEE_01770"
/note="Ligand binding site; other site"
/db_xref="CDD:133037"
misc_feature order(335539..335541,335545..335547,335929..335931)
/locus_tag="CGSHiEE_01770"
/note="metal-binding site"
/db_xref="CDD:133037"
gene 336011..336133
/locus_tag="CGSHiEE_01775"
/db_xref="GeneID:5224783"
CDS 336011..336133
/locus_tag="CGSHiEE_01775"
/note="COG1442 Lipopolysaccharide biosynthesis proteins,
LPS:glycosyltransferases"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290216.1"
/db_xref="GI:148825463"
/db_xref="GeneID:5224783"
/translation="MDKIIDIPSSWYDHFEKIPFLIKIKRLRKRIKDKLIYGIY"
gene 336292..336381
/locus_tag="CGSHiEE_t09360"
/db_xref="GeneID:5542118"
tRNA 336292..336381
/locus_tag="CGSHiEE_t09360"
/product="tRNA-Ser"
/db_xref="GeneID:5542118"
gene complement(336544..336867)
/locus_tag="CGSHiEE_01780"
/db_xref="GeneID:5224773"
CDS complement(336544..336867)
/locus_tag="CGSHiEE_01780"
/note="COG1544 Ribosome-associated protein Y (PSrp-1)"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290217.1"
/db_xref="GI:148825464"
/db_xref="GeneID:5224773"
/translation="MTLNITSKQMDITPAIREHLEERLAKLGKWQTQLISPHFVLNKV
PNGFTVEASIGTPLGNLLASATSDDMYKAINEVEEKLERQLNKLQHKSESRRANERLK
DSFEN"
misc_feature complement(336595..336861)
/locus_tag="CGSHiEE_01780"
/note="RaiA ('ribosome-associated inhibitor A', also known
as Protein Y (PY), YfiA, and SpotY, is a stress-response
protein that binds the ribosomal subunit interface and
arrests translation by interfering with aminoacyl-tRNA
binding to the ribosomal A site; Region: RaiA; cd00552"
/db_xref="CDD:29642"
misc_feature complement(order(336595..336597,336607..336612,
336652..336654,336661..336663,336667..336669,
336676..336678,336682..336684,336691..336702,
336709..336711,336736..336738,336748..336750,
336760..336765,336781..336783,336790..336792,
336844..336846,336850..336852,336856..336858))
/locus_tag="CGSHiEE_01780"
/note="30S subunit binding site; other site"
/db_xref="CDD:29642"
gene complement(337040..337672)
/locus_tag="CGSHiEE_01785"
/db_xref="GeneID:5224774"
CDS complement(337040..337672)
/locus_tag="CGSHiEE_01785"
/note="COG3317 Uncharacterized lipoprotein"
/codon_start=1
/transl_table=11
/product="putative deoxyribonucleotide triphosphate
pyrophosphatase"
/protein_id="YP_001290218.1"
/db_xref="GI:148825465"
/db_xref="GeneID:5224774"
/translation="MSLTTAIILVGCSSNPETLKASNDSFQKSEASIPHFSPLATGGV
QLPKADDAYSLPNIEVKKRGDIDIRPPLIPLAIIQNSITKFDGERSLIVYPKQEAKLY
NLQQVKRLLKEEGISSTTNGSILTTDWTKTERIGDKSIEIKYQIEQVMTPDVSAITVS
ILHMRRDGIIFTPNISDKQYYTSERLNRIVLALTTAYNKQLQDLSSTSIQ"
misc_feature complement(<337055..337600)
/locus_tag="CGSHiEE_01785"
/note="NlpB/DapX lipoprotein; Region: Lipoprotein_18;
pfam06804"
/db_xref="CDD:148421"
gene complement(337798..338694)
/locus_tag="CGSHiEE_01790"
/db_xref="GeneID:5224775"
CDS complement(337798..338694)
/locus_tag="CGSHiEE_01790"
/EC_number="4.2.1.52"
/note="catalyzes the formation of dihydrodipicolinate from
L-aspartate 4-semialdehyde and pyruvate in lysine and
diaminopimelate biosynthesis"
/codon_start=1
/transl_table=11
/product="dihydrodipicolinate synthase"
/protein_id="YP_001290219.1"
/db_xref="GI:148825466"
/db_xref="GeneID:5224775"
/translation="MSAQNPLFSGSIVALVTPMNHYGEVDFSCLEKLVEHHIEAGSNA
LVSVGTTGESATLSIEENVKVIEKTVEFAKGRIPIIAGAGANATSEAITMTKLLRDSG
VAGCLSVVPYYNKPTQEGIYQHFKAIAECTNLPQILYNVPSRTGSDMKPETVARLAKI
ENIVGIKEATGDVSRIVKIKQLAGKNFIVLSGDDATGLEAIKLGAEGVISVTNNIAAK
DMADMYRYALVGDFDKAEEINARLMRLHHDLFIESNPIPVKWAAYRLGLIKSSHLRLP
LTTLSEEIQPKVEDALKIAGLL"
misc_feature complement(337819..338673)
/locus_tag="CGSHiEE_01790"
/note="Dihydrodipicolinate synthase (DHDPS); Region:
DHDPS; cd00950"
/db_xref="CDD:188637"
misc_feature complement(337810..338667)
/locus_tag="CGSHiEE_01790"
/note="dihydrodipicolinate synthase; Region: dapA;
TIGR00674"
/db_xref="CDD:129757"
misc_feature complement(order(337867..337869,337873..337875,
337930..337935,338263..338265,338269..338271,
338356..338364,338431..338433,338437..338439,
338536..338550))
/locus_tag="CGSHiEE_01790"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:188637"
misc_feature complement(order(338113..338115,338119..338121,
338194..338196,338263..338265,338278..338280,
338542..338547))
/locus_tag="CGSHiEE_01790"
/note="active site"
/db_xref="CDD:188637"
misc_feature complement(338194..338196)
/locus_tag="CGSHiEE_01790"
/note="catalytic residue [active]"
/db_xref="CDD:188637"
gene 338795..339262
/gene="bcp"
/locus_tag="CGSHiEE_01795"
/db_xref="GeneID:5224776"
CDS 338795..339262
/gene="bcp"
/locus_tag="CGSHiEE_01795"
/EC_number="1.11.1.7"
/note="bacterioferritin comigratory protein; thiol
peroxidase; thioredoxin-dependent; hydroperoxide
peroxidase; in Escherichia coli this enzyme preferentially
reduces linoleic acid hydroperoxide; contains an active
site cysteine"
/codon_start=1
/transl_table=11
/product="thioredoxin-dependent thiol peroxidase"
/protein_id="YP_001290220.1"
/db_xref="GI:148825467"
/db_xref="GeneID:5224776"
/translation="MNPLSVGNQAPAFTLLNQQEKPVSLNDFRGKKVLIYFYPKALTP
GCTTQACGLRDSKSELDALGLVVLGISPDAPKKLAQFIEKKALNFTLLSDPDHQVAVQ
FGVWGEKKFMGRTYDGIHRISFLINESGNIMQVFDKFKIKDHHQMIIDYLRSL"
misc_feature 338801..>339190
/gene="bcp"
/locus_tag="CGSHiEE_01795"
/note="Peroxiredoxin [Posttranslational modification,
protein turnover, chaperones]; Region: AhpC; COG0450"
/db_xref="CDD:30799"
misc_feature 338819..339244
/gene="bcp"
/locus_tag="CGSHiEE_01795"
/note="Peroxiredoxin (PRX) family, Bacterioferritin
comigratory protein (BCP) subfamily; composed of
thioredoxin-dependent thiol peroxidases, widely expressed
in pathogenic bacteria, that protect cells against
toxicity from reactive oxygen species by reducing...;
Region: PRX_BCP; cd03017"
/db_xref="CDD:48566"
misc_feature order(338921..338923,338930..338932,339155..339157)
/gene="bcp"
/locus_tag="CGSHiEE_01795"
/note="catalytic triad [active]"
/db_xref="CDD:48566"
gene 339405..339857
/locus_tag="CGSHiEE_01800"
/db_xref="GeneID:5224777"
CDS 339405..339857
/locus_tag="CGSHiEE_01800"
/note="COG0811 Biopolymer transport proteins"
/codon_start=1
/transl_table=11
/product="transport protein ExbB"
/protein_id="YP_001290221.1"
/db_xref="GI:148825468"
/db_xref="GeneID:5224777"
/translation="MLQLFDFLQQYSDYFIIGLLLLMSVIMLAMVIERYLFLRKVNAA
HYSTIHALEIDLNRNMTVISTIGANAPYVGLLGTVIGILLTFYQIGHGGGDIDPSEIM
LHLSLALKATALGILVAIPSMVFYNGLGRKVEVNRLKWKVLNEQKDKE"
misc_feature 339420..339836
/locus_tag="CGSHiEE_01800"
/note="tonB-system energizer ExbB, group 2; Region: exbB2;
TIGR02805"
/db_xref="CDD:131852"
gene 339861..340304
/locus_tag="CGSHiEE_01805"
/db_xref="GeneID:5224778"
CDS 339861..340304
/locus_tag="CGSHiEE_01805"
/note="COG0848 Biopolymer transport protein"
/codon_start=1
/transl_table=11
/product="biopolymer transport protein"
/protein_id="YP_001290222.1"
/db_xref="GI:148825469"
/db_xref="GeneID:5224778"
/translation="MKKFDEINIIPFIDIMLVLLTVVLITASFISQGKIQVNVPKAST
AVAFKSDELAKLLTVTADKQLYFNDRPITQEALEAEIAQWNKDQKVTLKIDAEASFQD
FVTITDMLSKNEIKNVAIVSMKDKGKSAGKNSQESTPSQSVPTTP"
misc_feature 339870..340232
/locus_tag="CGSHiEE_01805"
/note="TonB system transport protein ExbD, group 2;
Region: ExbD_2; TIGR02804"
/db_xref="CDD:131851"
gene 340314..341105
/gene="bcp"
/locus_tag="CGSHiEE_01810"
/db_xref="GeneID:5224742"
CDS 340314..341105
/gene="bcp"
/locus_tag="CGSHiEE_01810"
/EC_number="1.11.1.7"
/note="COG0810 Periplasmic protein TonB, links inner and
outer membranes"
/codon_start=1
/transl_table=11
/product="TonB"
/protein_id="YP_001290223.1"
/db_xref="GI:148825470"
/db_xref="GeneID:5224742"
/translation="MQQTKRSLLGLLISLIVHGIVIGFILWNWNKPSDSANSAQGDIS
TSISMELLQGMVLEEPAPEPENVQKEPEPEPEPEPEKQEIVEDPTIKPEPKKIKEPEK
EKPKPKEKPKEKPKNKPKKEVKPQQKPINKDLPKGDKNIDSSANVNDKASTTSAANSN
AQVAGSGTDTSEIAAYRSAIRREIESHKRYPTRAKIMRKQGKVSVSFNVGADGSLSGA
RVTKSSGDESLDKAALDAINVSRSVGARPAGFPSSLSVQISFTLQ"
misc_feature <340704..341099
/gene="bcp"
/locus_tag="CGSHiEE_01810"
/note="Periplasmic protein TonB, links inner and outer
membranes [Cell envelope biogenesis, outer membrane];
Region: TonB; COG0810"
/db_xref="CDD:31152"
misc_feature 340872..341099
/gene="bcp"
/locus_tag="CGSHiEE_01810"
/note="Gram-negative bacterial tonB protein; Region: TonB;
pfam03544"
/db_xref="CDD:202680"
gene complement(341291..341797)
/locus_tag="CGSHiEE_01815"
/db_xref="GeneID:5224745"
CDS complement(341291..341797)
/locus_tag="CGSHiEE_01815"
/note="binds to single stranded DNA and may facilitate the
binding and interaction of other proteins to DNA"
/codon_start=1
/transl_table=11
/product="single-stranded DNA-binding protein"
/protein_id="YP_001290224.1"
/db_xref="GI:148825471"
/db_xref="GeneID:5224745"
/translation="MAGINKVIIVGHLGNDPEIRTMPNGDAVANISVATSESWNDRNT
GERREVTEWHRIVFYRRQAEICGEYLRKGSQVYVEGRLKTRKWQDQNGQDRYTTEIQG
DVMQMLGGRNQNAGGYSNDMGSTPQSSYQARQTNNGGSYQSSRPAPQQSAPQAEPPMD
GFDDDIPF"
misc_feature complement(341294..341794)
/locus_tag="CGSHiEE_01815"
/note="Single-stranded DNA-binding protein [DNA
replication, recombination, and repair]; Region: Ssb;
COG0629"
/db_xref="CDD:30974"
misc_feature complement(341474..341779)
/locus_tag="CGSHiEE_01815"
/note="SSB_OBF: A subfamily of OB folds similar to the OB
fold of ssDNA-binding protein (SSB). SSBs bind with high
affinity to ssDNA. They bind to and protect ssDNA
intermediates during DNA metabolic pathways. All bacterial
and eukaryotic SSBs studied to date...; Region: SSB_OBF;
cd04496"
/db_xref="CDD:72968"
misc_feature complement(order(341504..341506,341513..341515,
341546..341548,341573..341575,341636..341638,
341642..341644,341687..341695,341768..341779))
/locus_tag="CGSHiEE_01815"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:72968"
misc_feature complement(order(341495..341497,341501..341503,
341540..341545,341549..341551,341555..341557,
341579..341584,341621..341623,341627..341629,
341633..341635,341639..341641,341645..341650,
341684..341689,341708..341710,341738..341740,
341756..341764))
/locus_tag="CGSHiEE_01815"
/note="ssDNA binding site [nucleotide binding]; other
site"
/db_xref="CDD:72968"
misc_feature complement(order(341480..341482,341561..341563,
341567..341569,341573..341575))
/locus_tag="CGSHiEE_01815"
/note="tetramer (dimer of dimers) interface [polypeptide
binding]; other site"
/db_xref="CDD:72968"
misc_feature 341950..344782
/note="potential frameshift: common BLAST hit:
gi|16272207|ref|NP_438418.1| excinuclease ABC subunit A
[Haemophilus influenzae Rd KW20]"
misc_feature 345101..348431
/note="potential frameshift: common BLAST hit:
gi|68248855|ref|YP_247967.1| adhesion and penetration
protein Hap [Haemophilus influenzae]"
misc_feature 345858..349419
/note="potential frameshift: common BLAST hit:
gi|68248855|ref|YP_247967.1| adhesion and penetration
protein Hap [Haemophilus influenzae]"
gene 349563..350009
/gene="uvrA"
/locus_tag="CGSHiEE_01845"
/db_xref="GeneID:5225274"
CDS 349563..350009
/gene="uvrA"
/locus_tag="CGSHiEE_01845"
/note="COG3468 Type V secretory pathway, adhesin AidA"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290225.1"
/db_xref="GI:148825472"
/db_xref="GeneID:5225274"
/translation="MNLTKILPAFAAVVVLSACAKDAPEMTKSSAQIAEMQTLPTITD
KTVVYSCNKQTVTAVYQFENQEPVAAMVSVGDGIIAKDFIRDKSQNDFTSFVSGDYVW
NVDSGLTLDKFDSVVPVNLIQKGKSSDNIIVKNCDVNVKATKKANL"
gene 350133..351224
/gene="queA"
/locus_tag="CGSHiEE_01850"
/db_xref="GeneID:5225275"
CDS 350133..351224
/gene="queA"
/locus_tag="CGSHiEE_01850"
/note="Synthesizes oQ from preQ1 in a single
S-adenosylmethionine-requiring step"
/codon_start=1
/transl_table=11
/product="S-adenosylmethionine:tRNA
ribosyltransferase-isomerase"
/protein_id="YP_001290226.1"
/db_xref="GI:148825473"
/db_xref="GeneID:5225275"
/translation="MRVSDFNFDLPDELIARYPKTDRVSCRLLQLNGENGEIFHRTFS
DVLDLIDEGDLLIFNNTRVIPARMFGRKASGGKIEVLVERMLDEHRFLAHIRSSKSPK
EGAELFLGEDKLGENNGIKAVMKARHSSLFEVELSDKSTALLDVLQTIGHMPLPPYID
RPDEEADKECYQTVYSKVPGAVAAPTAGLHFDENLLEKLKAKGVNFEFVTLHVGAGTF
QPVRVENIEDHVMHAEYVEVSQEVCNAIIATKKAGKRVIAVGTTSVRSIESAALSAEE
FGNPDLIEPYFSDTSIFIYPGKKFRVVDCLITNFHLPESTLIMLVSAFAGYKNTMNAY
KQAVQEKYRFFSYGDAMFINKNSNVRELE"
misc_feature 350133..351191
/gene="queA"
/locus_tag="CGSHiEE_01850"
/note="S-adenosylmethionine:tRNA
ribosyltransferase-isomerase; Provisional; Region: queA;
PRK00147"
/db_xref="CDD:178900"
misc_feature 350136..351191
/gene="queA"
/locus_tag="CGSHiEE_01850"
/note="Queuosine biosynthesis protein; Region:
Queuosine_synth; pfam02547"
/db_xref="CDD:202279"
gene 351569..352717
/gene="tgt"
/locus_tag="CGSHiEE_01855"
/db_xref="GeneID:5225276"
CDS 351569..352717
/gene="tgt"
/locus_tag="CGSHiEE_01855"
/EC_number="2.4.2.29"
/note="Exchanges the guanine residue with
7-aminomethyl-7-deazaguanine in tRNAs with GU(N)
anticodons (tRNA-Asp, -Asn, -His and -Tyr)"
/codon_start=1
/transl_table=11
/product="queuine tRNA-ribosyltransferase"
/protein_id="YP_001290227.1"
/db_xref="GI:148825474"
/db_xref="GeneID:5225276"
/translation="MKYELDKTSGNARRGRLVFERPQGTFSVETPAFMPVGTYGTVKG
MTPEEVRATGAEILLGNTFHLWLRPGQEIMRKHGDLHDFMQWHRPILTDSGGFQVFSL
GKLRKITEEGVKFQNPINGERIFLSPEKSMEIQYDLGSDIVMIFDECTPYPATFDYAK
KSMEMSLRWAKRSRDRFDELGNKNALFGIIQGGVFEELRKVSLEGLVNIGFDGYAVGG
LAVGEPKEDMHRILEYICPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNA
RNGHLFVTDGIVKIRNAKYRDDTSPLDPECDCYTCKNYTKAYLYHLDKCGEILGARLN
TIHNLRYYQRLMAEIRQAIEDDRFDDFVVEFYARMGKPVPPLQLADKS"
misc_feature 351569..352627
/gene="tgt"
/locus_tag="CGSHiEE_01855"
/note="queuine tRNA-ribosyltransferase; Provisional;
Region: tgt; PRK00112"
/db_xref="CDD:178873"
misc_feature 351575..352690
/gene="tgt"
/locus_tag="CGSHiEE_01855"
/note="tRNA-guanine transglycosylases, various
specificities; Region: tgt_general; TIGR00449"
/db_xref="CDD:129541"
gene 352782..353300
/locus_tag="CGSHiEE_01860"
/db_xref="GeneID:5225099"
CDS 352782..353300
/locus_tag="CGSHiEE_01860"
/note="COG0457 FOG: TPR repeat"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290228.1"
/db_xref="GI:148825475"
/db_xref="GeneID:5225099"
/translation="MQILEPQQFATWNEPIEMLYACHSKVKRFCRQLSILPDYLEKHG
YTQAVLNDVEQILTYFNRAAPLHHDDEESDFFPQLVKVAPQAQTSIDELEKQHEYLHE
NWNALSVQLEELISEQRQDIDKHLIERFIQGYDRHIALEEPLFEMGRECLSADILTEM
GKHMSARRQVKE"
misc_feature 352824..353207
/locus_tag="CGSHiEE_01860"
/note="Hemerythrin HHE cation binding domain; Region:
Hemerythrin; pfam01814"
/db_xref="CDD:201988"
gene 353297..353518
/gene="tgt"
/locus_tag="CGSHiEE_01865"
/db_xref="GeneID:5225100"
CDS 353297..353518
/gene="tgt"
/locus_tag="CGSHiEE_01865"
/EC_number="2.4.2.29"
/note="COG0425 Predicted redox protein, regulator of
disulfide bond formation"
/codon_start=1
/transl_table=11
/product="queuine tRNA-ribosyltransferase"
/protein_id="YP_001290229.1"
/db_xref="GI:148825476"
/db_xref="GeneID:5225100"
/translation="MKYQLNLTALRCPIPLLSAKKALKNLDKNDELMLILNLESAVEN
FSIFAEENSVALVEQYYASEKEFIVILKK"
misc_feature 353306..353512
/gene="tgt"
/locus_tag="CGSHiEE_01865"
/note="SirA, YedF, and YeeD. Two-layered alpha/beta
sandwich domain. SirA (also known as UvrY, and YhhP)
belongs to a family of bacterial two-component response
regulators that controls secondary metabolism and
virulence. The other member of this...; Region:
SirA_YedF_YeeD; cd00291"
/db_xref="CDD:48205"
misc_feature order(353309..353314,353321..353323,353330..353341,
353345..353347)
/gene="tgt"
/locus_tag="CGSHiEE_01865"
/note="CPxP motif; other site"
/db_xref="CDD:48205"
gene 353626..353919
/gene="yajC"
/locus_tag="CGSHiEE_01870"
/db_xref="GeneID:5225101"
CDS 353626..353919
/gene="yajC"
/locus_tag="CGSHiEE_01870"
/note="member of preprotein translocase; forms a
heterotrimer with SecD and SecF; links the
SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG
complex"
/codon_start=1
/transl_table=11
/product="preprotein translocase subunit YajC"
/protein_id="YP_001290230.1"
/db_xref="GI:148825477"
/db_xref="GeneID:5225101"
/translation="MEAQSPMSTLFIFVIFGLIFYFMIYRPQAKRNKEHKKLMSELAK
GTEVLTAGGLIGKITKVTEGSDSIVIALNDTTEITINRNYIVSVLPKGSLKSL"
misc_feature 353626..353916
/gene="yajC"
/locus_tag="CGSHiEE_01870"
/note="preprotein translocase subunit YajC; Validated;
Region: yajC; PRK05585"
/db_xref="CDD:180149"
misc_feature 353989..355838
/note="potential frameshift: common BLAST hit:
gi|68248848|ref|YP_247960.1| protein export protein SecD
[Haemophilus influenzae 86-028NP]"
gene 355849..356823
/gene="secF"
/locus_tag="CGSHiEE_01885"
/db_xref="GeneID:5225102"
CDS 355849..356823
/gene="secF"
/locus_tag="CGSHiEE_01885"
/note="forms a complex with SecD and YajC; SecDFyajC
stimulates the proton motive force-driven protein
translocation; seems to modulate the cycling of SecA by
stabilizing its membrane-inserted state and appears to be
required for the release of mature proteins from the
extracytoplasmic side of the membrane; in some organisms,
such as Bacillus subtilis, SecD is fused to SecF"
/codon_start=1
/transl_table=11
/product="preprotein translocase subunit SecF"
/protein_id="YP_001290231.1"
/db_xref="GI:148825478"
/db_xref="GeneID:5225102"
/translation="MKLFTKDKGGHFIREINGIKLPFPLTEFMKVRKLGYILSALLMV
ISLFFIITKGFNWGLDFTGGVVFDTHFSQSANLEQIRNKLHENGIESPVVQTTGSVQD
VMIRLPASNNDSTIGEHVKSMLQNVDKDIQIRSIEFVGPNVGEELAQGAVYATLATLA
MVLIYVGSRFEWRLGFGSIASLAHDVIITLGVFSALQIEIDLTFVAAILSVVGYSIND
SIVVFDRVRENFRKIRRLDTIDIIDISLTQTLSRTIITSVTTLVVVMALFFFGGPSIH
NFSLALLVGIGFGTYSSIFVAIAIAYDVGLRREHMIPPKVDKEIDELP"
misc_feature 355927..356781
/gene="secF"
/locus_tag="CGSHiEE_01885"
/note="preprotein translocase subunit SecF; Reviewed;
Region: secF; PRK13022"
/db_xref="CDD:183847"
misc_feature 355993..356079
/gene="secF"
/locus_tag="CGSHiEE_01885"
/note="SecD/SecF GG Motif; Region: Sec_GG; pfam07549"
/db_xref="CDD:116168"
misc_feature 356203..356769
/gene="secF"
/locus_tag="CGSHiEE_01885"
/note="Protein export membrane protein; Region: SecD_SecF;
pfam02355"
/db_xref="CDD:111266"
gene complement(356939..357988)
/locus_tag="CGSHiEE_01890"
/db_xref="GeneID:5225103"
CDS complement(356939..357988)
/locus_tag="CGSHiEE_01890"
/note="COG0628 Predicted permease"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290232.1"
/db_xref="GI:148825479"
/db_xref="GeneID:5225103"
/translation="MLEMLKSWYSRRLSDPQAMGLLAILLFGFISIYFFGDLIAPLLI
ALVLSYLLEIPINFLNQYLKCPRMLATILIFGSFIGLAAIFFLVLVPMLWNQTISLLS
DLPAMFNKSNEWLLNLPENYPELIDYSMVDSIFNSVREKILGFGESAVKLSLASIMNL
VSLGIYAFLVPLMMFFMLKDKSELLQGVSRFLPKNRNLAFKVWKEMQQQISNYIHGKL
LEILIVTLITYIIFLIFGLNYSLLLAFAVGLSVLVPYIGAVIVTIPVALVALFQFGIS
PTFWYIIIAFAVSQLLDGNLLVPYLFSEAVNLHPLIIIISVLIFGGLWGFWGVFFAIP
LATLVKAVINALPQD"
misc_feature complement(356948..357937)
/locus_tag="CGSHiEE_01890"
/note="Domain of unknown function DUF20; Region: UPF0118;
pfam01594"
/db_xref="CDD:201878"
misc_feature complement(357041..357937)
/locus_tag="CGSHiEE_01890"
/note="pheromone autoinducer 2 transporter; Reviewed;
Region: tqsA; cl00465"
/db_xref="CDD:207060"
gene 358066..358416
/locus_tag="CGSHiEE_01895"
/db_xref="GeneID:5225051"
CDS 358066..358416
/locus_tag="CGSHiEE_01895"
/note="COG1393 Arsenate reductase and related proteins,
glutaredoxin family"
/codon_start=1
/transl_table=11
/product="putative arsenate reductase"
/protein_id="YP_001290233.1"
/db_xref="GI:148825480"
/db_xref="GeneID:5225051"
/translation="MSVIIYHNPHCSKSRETLALLENQGIQPIIELYLQKQYSIDELK
SIAQKLGIDDVRQMMRTKDDLYKSLNLDNLELSQAELLKAMSEHSALIERPIVINGDK
AKIGRPPETVLEIL"
misc_feature 358072..358410
/locus_tag="CGSHiEE_01895"
/note="Arsenate Reductase (ArsC) family, ArsC subfamily;
arsenic reductases similar to that encoded by arsC on the
R733 plasmid of Escherichia coli. E. coli ArsC catalyzes
the reduction of arsenate [As(V)] to arsenite [As(III)],
the first step in the...; Region: ArsC_ArsC; cd03034"
/db_xref="CDD:48583"
misc_feature 358081..358410
/locus_tag="CGSHiEE_01895"
/note="ArsC family; Region: ArsC; pfam03960"
/db_xref="CDD:202832"
misc_feature order(358096..358098,358243..358245,358345..358347,
358384..358386)
/locus_tag="CGSHiEE_01895"
/note="catalytic residues [active]"
/db_xref="CDD:48583"
gene 358484..358729
/locus_tag="CGSHiEE_01900"
/db_xref="GeneID:5225052"
CDS 358484..358729
/locus_tag="CGSHiEE_01900"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290234.1"
/db_xref="GI:148825481"
/db_xref="GeneID:5225052"
/translation="MAKQQKSAVENETVYQHTRGVIKDNAVMALLGDKLFRQRIEKKR
KGKGSYQRKVKHPGKMFEKPDYKFFDYRNFIIGFFLG"
misc_feature 358526..358699
/locus_tag="CGSHiEE_01900"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG3036"
/db_xref="CDD:32850"
gene 358749..359045
/locus_tag="CGSHiEE_01905"
/db_xref="GeneID:5225053"
CDS 358749..359045
/locus_tag="CGSHiEE_01905"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290235.1"
/db_xref="GI:148825482"
/db_xref="GeneID:5225053"
/translation="MSKQPQILLNNTWNVRISDPGEEGAKSHFFERIYLTLTAYFEEN
NIRYEFVRKVEDQIKIQRSFTELNELFKFLGDYVDPVSIGLLGVKIGNLGIKSE"
gene complement(359178..359330)
/locus_tag="CGSHiEE_01910"
/db_xref="GeneID:5225054"
CDS complement(359178..359330)
/locus_tag="CGSHiEE_01910"
/note="COG3036 Uncharacterized protein conserved in
bacteria"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290236.1"
/db_xref="GI:148825483"
/db_xref="GeneID:5225054"
/translation="MVKRKTFLKKKANLQQSSLSRNLRLRRLKHRKQKQFSRHSLQFV
VQEICC"
gene complement(359335..360783)
/locus_tag="CGSHiEE_01915"
/db_xref="GeneID:5225055"
CDS complement(359335..360783)
/locus_tag="CGSHiEE_01915"
/note="YfhD; uncharacterized member of the
transglycosylase slt family; part of the rob operon, which
plays a role in cellular resistance to antibiotics,
bactericidal agents, and organic solvents; unknown
function"
/codon_start=1
/transl_table=11
/product="putative transglycosylase"
/protein_id="YP_001290237.1"
/db_xref="GI:148825484"
/db_xref="GeneID:5225055"
/translation="MKGLFLRIITALALLFWAIDMVFPWQFLRHTEENHYAAIQSRGA
LYVGTINNQISYFTNNDGERGFEYELAKAFADSLGVELEMKTFDNQEQLFDELDKHNI
DLAAAHILYHPKNAERFQIGPAYHSASWQLAYRKNENRPKNLGNVKKDIYISNNLALE
ETLKELQKQYPQLTWKRNQTLTQEELLLQLAEGKIPYVIANSIDIAAMQQIKPELAIA
FDITDEANVHWYLPNKSYHDLQTALLNFMNNAEETGLLDNLKEKYLGHISQFDYVDTR
SYMNAIENTLPQYSPLFEKYQGELDWRLLAAVAYQESHWDPHATSPTGVRGIMMLTKN
TAQHMKISDRTNPEQSIKAGSEYLHWLISQLPESIEKEEKIWFALVAYNIGLGHLIDA
RRLTQNLGGNPDNWLDVKKNLPLLAEKRYYSQLKYGYARGYEAYQYVENIRRYMNSIV
NYHRVQENQIINDNASNESAVKNLEEIKENKD"
misc_feature complement(359407..360783)
/locus_tag="CGSHiEE_01915"
/note="membrane-bound lytic transglycosylase F;
Provisional; Region: PRK10859"
/db_xref="CDD:182785"
misc_feature complement(359992..360651)
/locus_tag="CGSHiEE_01915"
/note="Bacterial periplasmic transport systems use
membrane-bound complexes and substrate-bound,
membrane-associated, periplasmic binding proteins (PBPs)
to transport a wide variety of substrates, such as, amino
acids, peptides, sugars, vitamins and inorganic...;
Region: PBPb; cd00134"
/db_xref="CDD:29040"
misc_feature complement(order(360181..360183,360310..360312,
360439..360441,360517..360519,360625..360627))
/locus_tag="CGSHiEE_01915"
/note="substrate binding pocket [chemical binding]; other
site"
/db_xref="CDD:29040"
misc_feature complement(order(360202..360204,360220..360222,
360232..360234))
/locus_tag="CGSHiEE_01915"
/note="membrane-bound complex binding site; other site"
/db_xref="CDD:29040"
misc_feature complement(360097..360114)
/locus_tag="CGSHiEE_01915"
/note="hinge residues; other site"
/db_xref="CDD:29040"
misc_feature complement(359602..359880)
/locus_tag="CGSHiEE_01915"
/note="Lytic Transglycosylase (LT) and Goose Egg White
Lysozyme (GEWL) domain. Members include the soluble and
insoluble membrane-bound LTs in bacteria, the LTs in
bacteriophage lambda, as well as, the eukaryotic
'goose-type' lysozymes (GEWL). LTs catalyze...; Region:
LT_GEWL; cd00254"
/db_xref="CDD:29556"
misc_feature complement(order(359638..359640,359713..359715,
359788..359790,359848..359850))
/locus_tag="CGSHiEE_01915"
/note="N-acetyl-D-glucosamine binding site [chemical
binding]; other site"
/db_xref="CDD:29556"
misc_feature complement(359848..359850)
/locus_tag="CGSHiEE_01915"
/note="catalytic residue [active]"
/db_xref="CDD:29556"
gene complement(360901..362742)
/gene="secF"
/locus_tag="CGSHiEE_01920"
/db_xref="GeneID:5224997"
CDS complement(360901..362742)
/gene="secF"
/locus_tag="CGSHiEE_01920"
/note="COG0513 Superfamily II DNA and RNA helicases"
/codon_start=1
/transl_table=11
/product="preprotein translocase subunit SecF"
/protein_id="YP_001290238.1"
/db_xref="GI:148825485"
/db_xref="GeneID:5224997"
/translation="MTDKITFNDLGLPEFILKAVSDLGFETPSPIQQACIPHLLSGND
VLGMAQTGSGKTAAFALPLLAQIDPSEKHPQMLVMAPTRELAIQVADACEQFVKYAHG
SRIVTLYGGQRYDIQLRALKQGAQVVVGTPGRILDHIRRGTLNLSELRFIVLDEADEM
LRMGFIDDVETVMAELPENHQTALFSATMPEPIRRITKRFMNDPKEVKIKVNNENAPD
IEQSCWYVHGVRKNEALLRFLEVEDFDAAIIFARTKTGTLDITELLEKNGFRSAALNG
DMTQQLREQTLDRLRNGSLDIVVATDVAARGIDIERISLVVNYDIPLDAESYVHRIGR
TGRAGRSGRALLFVEPRERRLLRNIEHLMKKGINEVELPNHLVLQECRRKKFVAKITK
QLEHHDLEQYRSLLEDLFTADQDQEDIAAAMLMLLQGKQKLILPPDPPMEKRRRERND
RGDRRENPRSAERRGERKGYGNPQAMDLYRIEVGRADGVEVRHIVGAIANEGDINSRY
IGHIKLYDDYTTVELPQGMPKELLQQFGKTRVLNKQMQMSFLGAVKSDNSRGSDDFNG
KRKGRGSDFRGERGRERGNDNRGNRKFNEKSNRTFSDKPRRDRRSSF"
misc_feature complement(361036..362742)
/gene="secF"
/locus_tag="CGSHiEE_01920"
/note="ATP-dependent RNA helicase DeaD; Provisional;
Region: PRK11634"
/db_xref="CDD:183247"
misc_feature complement(362119..362724)
/gene="secF"
/locus_tag="CGSHiEE_01920"
/note="DEAD-box helicases. A diverse family of proteins
involved in ATP-dependent RNA unwinding, needed in a
variety of cellular processes including splicing, ribosome
biogenesis and RNA degradation. The name derives from the
sequence of the Walker B motif; Region: DEADc; cd00268"
/db_xref="CDD:28928"
misc_feature complement(362575..362589)
/gene="secF"
/locus_tag="CGSHiEE_01920"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:28928"
misc_feature complement(362269..362280)
/gene="secF"
/locus_tag="CGSHiEE_01920"
/note="Mg++ binding site [ion binding]; other site"
/db_xref="CDD:28928"
misc_feature complement(362179..362187)
/gene="secF"
/locus_tag="CGSHiEE_01920"
/note="motif III; other site"
/db_xref="CDD:28928"
misc_feature complement(361753..362073)
/gene="secF"
/locus_tag="CGSHiEE_01920"
/note="Helicase superfamily c-terminal domain; associated
with DEXDc-, DEAD-, and DEAH-box proteins, yeast
initiation factor 4A, Ski2p, and Hepatitis C virus NS3
helicases; this domain is found in a wide variety of
helicases and helicase related proteins; may...; Region:
HELICc; cd00079"
/db_xref="CDD:28960"
misc_feature complement(order(361834..361842,361915..361920,
361978..361989))
/gene="secF"
/locus_tag="CGSHiEE_01920"
/note="nucleotide binding region [chemical binding]; other
site"
/db_xref="CDD:28960"
misc_feature complement(order(361753..361755,361816..361818))
/gene="secF"
/locus_tag="CGSHiEE_01920"
/note="ATP-binding site [chemical binding]; other site"
/db_xref="CDD:28960"
misc_feature complement(361093..361308)
/gene="secF"
/locus_tag="CGSHiEE_01920"
/note="DbpA RNA binding domain; Region: DbpA; pfam03880"
/db_xref="CDD:202795"
gene complement(362921..363754)
/locus_tag="CGSHiEE_01925"
/db_xref="GeneID:5224998"
CDS complement(362921..363754)
/locus_tag="CGSHiEE_01925"
/note="lipoprotein that appears to be involved in cell
division; interacts with the periplasmic protease Prc and
may be activated by protease processing"
/codon_start=1
/transl_table=11
/product="lipoprotein NlpI"
/protein_id="YP_001290239.1"
/db_xref="GI:148825486"
/db_xref="GeneID:5224998"
/translation="MSKNHVVLAEQNPNTHFEQEVMIVRLSQVLLVGKMSNEERASLH
FERGVLYDSLGLWGLARYDLTQALALQPKMASVYNYLGLYLLLEEDYDGALDAFNTVF
ELDSGYDYTHLNRGLNFYYVGRYHLAQQDFLQFYQADTKDPYRVLWLYLNEQKLKPQE
AQTNLVERAKGLSEDFWGTHIVQYYLGHISVEELQQRANGFAENSQQYAEILTETYFY
LAKQKLNVGLVDEAAALFKLAMANQVYNFVEYRFAAFELMKLKPVQTEDEKEEKSAVA
K"
misc_feature complement(362936..363754)
/locus_tag="CGSHiEE_01925"
/note="lipoprotein NlpI; Provisional; Region: PRK11189"
/db_xref="CDD:183026"
gene complement(363935..366064)
/locus_tag="CGSHiEE_01930"
/db_xref="GeneID:5224999"
CDS complement(363935..366064)
/locus_tag="CGSHiEE_01930"
/note="COG1185 Polyribonucleotide nucleotidyltransferase
(polynucleotide phosphorylase)"
/codon_start=1
/transl_table=11
/product="polynucleotide phosphorylase/polyadenylase"
/protein_id="YP_001290240.1"
/db_xref="GI:148825487"
/db_xref="GeneID:5224999"
/translation="MNPIVKQFKYGQHTVTLETGAIARQATAAVMASMDDTTVFVTVV
AKKDVKEGQDFFPLTVNYQERTYAAGKIPGGFFKREGRPSEGETLIARLIDRPIRPLF
PEGFFNEIQVVATVVSVNPQISPDLVAMIGASAALTLSGVPFNGPIGAARVGFIDNQF
VLNPTMAEQKQSRLDLVVAGTDKAVLMVESEADVLTEEQMLASVVFGHQQQQVVIEAI
KEFAKEAGKPRWDWVAPQPNTDLINKVKAIAEARLGDAYRITEKQLRYEQIDAIKADV
IAQITAEDEEISEGKIVDIFTALESQIVRGRIIAGEPRIDGRTVDTVRALDICTGVLP
RTHGSAIFTRGETQALAVATLGTERDAQIIDELTGERQDHFLFHYNFPPYSVGETGMI
GSPKRREIGHGRLAKRGVAAVMPSLAEFPYVVRVVSEITESNGSSSMASVCGASLALM
DAGVPIKAAVAGIAMGLVKEEEKFVVLSDILGDEDHLGDMDFKVAGTREGVTALQMDI
KIEGITPEIMQIALNQAKSARMHILGVMEQAIPAPRADISDYAPRIYTMKIDPKKIKD
VIGKGGATIRSLTEETGTSIDIDDDGTVKIAAVDSNAAKNVMGRIEEIVAEVEAGAIY
KGKVTRLADFGAFVAIVGNKEGLVHISQIAEERVEKVSDYLQVGQEVNVKVVEIDRQG
RIRLTMKDLAPKQETEINQEDPVEEQE"
misc_feature complement(363992..366064)
/locus_tag="CGSHiEE_01930"
/note="polynucleotide phosphorylase/polyadenylase;
Provisional; Region: PRK11824"
/db_xref="CDD:183327"
misc_feature complement(365369..366055)
/locus_tag="CGSHiEE_01930"
/note="Polyribonucleotide nucleotidyltransferase, repeat
1; Region: RNase_PH_PNPase_1; cd11363"
/db_xref="CDD:206768"
misc_feature complement(order(365951..365953,365960..365962,
365966..365968,365972..365974,366002..366004,
366011..366013,366017..366019,366044..366046,
366050..366052))
/locus_tag="CGSHiEE_01930"
/note="RNase E interface [polypeptide binding]; other
site"
/db_xref="CDD:206768"
misc_feature complement(order(365702..365716,365726..365728,
365732..365734,365738..365740,365813..365815,
365825..365839,365846..365857,365861..365872,
365876..365878,365882..365884,365927..365929,
365933..365935,365939..365941,365945..365947,
365972..365974,365987..366004))
/locus_tag="CGSHiEE_01930"
/note="trimer interface [polypeptide binding]; other site"
/db_xref="CDD:206768"
misc_feature complement(365108..365347)
/locus_tag="CGSHiEE_01930"
/note="Polyribonucleotide nucleotidyltransferase, RNA
binding domain; Region: PNPase; pfam03726"
/db_xref="CDD:202745"
misc_feature complement(364436..365101)
/locus_tag="CGSHiEE_01930"
/note="Polyribonucleotide nucleotidyltransferase, repeat
2; Region: RNase_PH_PNPase_2; cd11364"
/db_xref="CDD:206769"
misc_feature complement(order(364445..364450,364460..364462,
364472..364474,364484..364486,365063..365065,
365072..365101))
/locus_tag="CGSHiEE_01930"
/note="RNase E interface [polypeptide binding]; other
site"
/db_xref="CDD:206769"
misc_feature complement(order(364766..364774,364778..364780,
364784..364786,364790..364792,364880..364882,
364886..364888,364895..364903,364907..364918,
364925..364927,364931..364933,364979..364987,
364997..365005,365009..365011,365015..365017,
365027..365032,365054..365068,365078..365080,
365084..365086))
/locus_tag="CGSHiEE_01930"
/note="trimer interface [polypeptide binding]; other site"
/db_xref="CDD:206769"
misc_feature complement(order(364544..364546,364550..364552,
364586..364588,364592..364594,364610..364612,
364751..364759,364859..364861,364871..364873,
364922..364924,364928..364930))
/locus_tag="CGSHiEE_01930"
/note="active site"
/db_xref="CDD:206769"
misc_feature complement(364250..364411)
/locus_tag="CGSHiEE_01930"
/note="Polynucleotide phosphorylase (PNPase) K homology
RNA-binding domain (KH). PNPase is a polyribonucleotide
nucleotidyl transferase that degrades mRNA in prokaryotes
and plant chloroplasts. The C-terminal region of PNPase
contains domains homologous to...; Region: PNPase_KH;
cd02393"
/db_xref="CDD:29003"
misc_feature complement(order(364301..364312,364325..364330,
364337..364342,364349..364363,364367..364375,
364379..364381))
/locus_tag="CGSHiEE_01930"
/note="putative nucleic acid binding region [nucleotide
binding]; other site"
/db_xref="CDD:29003"
misc_feature complement(364349..364360)
/locus_tag="CGSHiEE_01930"
/note="G-X-X-G motif; other site"
/db_xref="CDD:29003"
misc_feature complement(364001..364204)
/locus_tag="CGSHiEE_01930"
/note="S1_PNPase: Polynucleotide phosphorylase (PNPase),
), S1-like RNA-binding domain. PNPase is a
polyribonucleotide nucleotidyl transferase that degrades
mRNA. It is a trimeric multidomain protein. The C-terminus
contains the S1 domain which binds ssRNA; Region:
S1_PNPase; cd04472"
/db_xref="CDD:88437"
misc_feature complement(order(364118..364120,364124..364126,
364154..364156,364178..364180))
/locus_tag="CGSHiEE_01930"
/note="RNA binding site [nucleotide binding]; other site"
/db_xref="CDD:88437"
misc_feature complement(364058..364063)
/locus_tag="CGSHiEE_01930"
/note="domain interface; other site"
/db_xref="CDD:88437"
gene 366420..366938
/locus_tag="CGSHiEE_01935"
/db_xref="GeneID:5225000"
CDS 366420..366938
/locus_tag="CGSHiEE_01935"
/note="COG1442 Lipopolysaccharide biosynthesis proteins,
LPS:glycosyltransferases"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290241.1"
/db_xref="GI:148825488"
/db_xref="GeneID:5225000"
/translation="MINGNITLPFEYLDFSRHTIAAVLDPYVTRIGHPYKDKDYFNAG
VLYFNMDKYQLGISSFSKELITLHTQLKESLIYGDQDILNYYFEDQWIPLDKRYNFQL
DHMISINNLDISPVIFHFTGPHKPLDNIFSENVCVNAVISLFRLYASISWQDIYSLPL
GTIRANWINQER"
misc_feature <366423..366797
/locus_tag="CGSHiEE_01935"
/note="Glycosyltransferase family A (GT-A) includes
diverse families of glycosyl transferases with a common
GT-A type structural fold; Region: Glyco_tranf_GTA_type;
cl11394"
/db_xref="CDD:212311"
gene 367014..367481
/locus_tag="CGSHiEE_01940"
/db_xref="GeneID:5225001"
CDS 367014..367481
/locus_tag="CGSHiEE_01940"
/note="COG2731 Beta-galactosidase, beta subunit"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290242.1"
/db_xref="GI:148825489"
/db_xref="GeneID:5225001"
/translation="MIISSLTNPNFKVGLPKVITEVCDYLNTLDLNALENGRHDINDQ
IYMNVMEPETAESSSKKAELHHEYLDVQVLIRGTENIEVGATYPNLSKYEDYNEADDY
QLCADIDDKFTVTMKPKMFAVFYPYEPHKPCCVVNGKTEKIKKLVVKVPVKLI"
misc_feature 367014..367436
/locus_tag="CGSHiEE_01940"
/note="uncharacterized protein, YhcH/YjgK/YiaL family;
Region: TIGR00022"
/db_xref="CDD:129133"
gene complement(367589..368932)
/locus_tag="CGSHiEE_01945"
/db_xref="GeneID:5225002"
CDS complement(367589..368932)
/locus_tag="CGSHiEE_01945"
/note="COG1114 Branched-chain amino acid permeases"
/codon_start=1
/transl_table=11
/product="branched-chain amino acid transport system II
carrier protein"
/protein_id="YP_001290243.1"
/db_xref="GI:148825490"
/db_xref="GeneID:5225002"
/translation="MQAFLFLESKIMFSRKDIIVLGMMIFALFLGAGNIIFPPMEGFS
AGQHWTSASLGFVLTGVLMPFITLVVVAILGRGEELTKDLPKWAGTGFLVILYLTIGS
TFAMPRITNVAYEMAWLPLDLVEDNANVRFLFSLIFNLIAMGFMISPNTIISSVGKFM
TPALLVLLIAVAITVFISPLSEIQAPSNAYENSHSLLIGLTSGYQTMDVLAAIAFGGI
VARALSAKNMTKTKDIVKYTISAGFVSVILLAGLYFSLFYLGATSAAVAEGATNGGQI
FSRYVNVLFGSAGTWIMAGIIVLASLTTLVGVTSASADYFSKFSVRFSYPFWAALFTA
MTITVSQYGLTDLLRITIPALLLIYPVAIVLVLLQFLRKKLPSIKFTYNSTLLVTVCF
SLCDSLNNVKMLPESINSLLKHFPLSSEGMAWLVPTLVMLVASIFIGKALRKTHS"
misc_feature complement(367607..368893)
/locus_tag="CGSHiEE_01945"
/note="Branched-chain amino acid transport protein;
Region: Branch_AA_trans; pfam05525"
/db_xref="CDD:114257"
gene 369087..370289
/locus_tag="CGSHiEE_01950"
/db_xref="GeneID:5224991"
CDS 369087..370289
/locus_tag="CGSHiEE_01950"
/note="exports sodium by using the electrochemical proton
gradient to allow protons into the cell; functions in
adaptation to high salinity and alkaline pH; activity
increases at higher pH; downregulated at acidic pH"
/codon_start=1
/transl_table=11
/product="pH-dependent sodium/proton antiporter"
/protein_id="YP_001290244.1"
/db_xref="GI:148825491"
/db_xref="GeneID:5224991"
/translation="MNFLLCIFKGVYVIKLIQRFFKLESAGGILLLFSAVVAMLLANS
PLSNQYNDFLNLPVSLQIGSFSINKTLIHWINDGFMAVFFVLVGMEVKKELFEGALST
YQQAIFPAIAAIGGMVIPAVVYWFIAKQDPSLANGWAIPMATDIAFALGIMALLSKQV
PLPLKIFLLALAIIDDLGAIVVIALFFSHGLSVQALIFSAVAIIALILLNRFKVSALC
AYMVVGAILWASVLKSGVHATLAGVIIGFSIPLKGKKGERPLDDFEHILASWSSFVIL
PLFAFANAGVSFAGIDVNMISSPLLLAIASGLIIGKPVGIFGFSYISVKLGLAKLPDG
INFKQIFAVAVLCGIGFTMSMFLASLAFDANAGESVNTLSRLGILFGSTVSAILGYLF
LKQTTKLS"
misc_feature 369126..370280
/locus_tag="CGSHiEE_01950"
/note="pH-dependent sodium/proton antiporter; Reviewed;
Region: nhaA; PRK09560"
/db_xref="CDD:181954"
gene complement(370328..370789)
/locus_tag="CGSHiEE_01955"
/db_xref="GeneID:5224992"
CDS complement(370328..370789)
/locus_tag="CGSHiEE_01955"
/note="COG1522 Transcriptional regulators"
/codon_start=1
/transl_table=11
/product="putative transcriptional regulator"
/protein_id="YP_001290245.1"
/db_xref="GI:148825492"
/db_xref="GeneID:5224992"
/translation="MQTLDKLDRNILNVLQQDAMIPLKELSEKVNSSVATCQRRVQAL
TDSGVITKRVAVVSPKAVGRTISVFVMVEMDNQHSYYQEQFERKMRQEDEVVSCYEIS
GDYDFMLLLHAKDMESYHAFTRRVLTGEFHVRTYKSLFVMNFTKADSGIIL"
misc_feature complement(370451..370780)
/locus_tag="CGSHiEE_01955"
/note="helix_turn_helix ASNC type; Region: HTH_ASNC;
smart00344"
/db_xref="CDD:197668"
misc_feature complement(370637..370780)
/locus_tag="CGSHiEE_01955"
/note="Winged helix-turn-helix DNA-binding; Region:
HTH_24; pfam13412"
/db_xref="CDD:205590"
misc_feature complement(order(370631..370636,370652..370657,
370661..370666,370673..370678,370682..370693,
370718..370726,370766..370774))
/locus_tag="CGSHiEE_01955"
/note="putative DNA binding site [nucleotide binding];
other site"
/db_xref="CDD:28974"
misc_feature complement(order(370715..370717,370724..370726))
/locus_tag="CGSHiEE_01955"
/note="putative Zn2+ binding site [ion binding]; other
site"
/db_xref="CDD:28974"
misc_feature complement(370361..370582)
/locus_tag="CGSHiEE_01955"
/note="AsnC family; Region: AsnC_trans_reg; pfam01037"
/db_xref="CDD:189815"
gene 370909..371799
/locus_tag="CGSHiEE_01960"
/db_xref="GeneID:5224993"
CDS 370909..371799
/locus_tag="CGSHiEE_01960"
/note="COG2962 Predicted permeases"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290246.1"
/db_xref="GI:148825493"
/db_xref="GeneID:5224993"
/translation="MKVVIQGVLLCIFSQCLFGILYLFSIWLQPLSGTDVFAWRMLTM
IFGLLLILFPTIGCRSLLSLITTTLGKSWTRWVLFLLGTLDAGSQFWLFMWAPLNGEG
INIAMGYFLFPLIMAVLGWAWLKERLSFIQKIALLLAACGVAHELWHTQSFSWTSLWV
CTVYPFYYLSRKWMKIPALQGITLDIILISIPCFIYILSQSDTLSLVTQEYRYWLLLP
ALGIVSAISLSANLKSSQQIPVSIFAVLSYIEPILLFLIAVFVLDNQITTSDYFTYVP
IWLSLIVIGIEGLLNKNKVR"
misc_feature 370912..371796
/locus_tag="CGSHiEE_01960"
/note="Predicted permeases [General function prediction
only]; Region: RarD; COG2962"
/db_xref="CDD:32782"
misc_feature 371017..371355
/locus_tag="CGSHiEE_01960"
/note="EamA-like transporter family; Region: EamA;
cl01037"
/db_xref="CDD:207295"
gene complement(371861..373432)
/gene="guaA"
/locus_tag="CGSHiEE_01965"
/db_xref="GeneID:5224994"
CDS complement(371861..373432)
/gene="guaA"
/locus_tag="CGSHiEE_01965"
/EC_number="6.3.5.2"
/note="contains glutamine-hydrolyzing domain and glutamine
amidotransferase; GMP-binding domain; functions to produce
GMP from XMP in the IMP pathway"
/codon_start=1
/transl_table=11
/product="GMP synthase"
/protein_id="YP_001290247.1"
/db_xref="GI:148825494"
/db_xref="GeneID:5224994"
/translation="MTNIHNHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQ
IREFAPTGIILSGSPESTTEENSPRAPEYVFNAGVPVLGVCYGMQTMAMQLGGLTETS
DHREFGYASVSLENSTALFANLNDNLTASEPKLDVWMSHGDKVTRLPQNFQVTGTTPT
CPIAAMSDESRRFYGVQFHPEVTHTKKGLELLTNFVVNICGCETKWTAENIIEDAVAR
IKEQVGDDEVILGLSGGVDSSVVALLLHRAIGKNLHCVFVDNGLLRLHEGDQVMEMFG
DKFGLNITRVDAESRFLGELAGVSDPEAKRKIIGKVFVDVFDDESKKLTNVKWLAQGT
IYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLP
AEMINRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRNSGWYEKTSQAFSVFL
PVKSVGVMGDGRKYDWVISLRAVETIDFMTAHWAHLPYDLLGKVSNRIINEVNGISRV
VYDISGKPPATIEWE"
misc_feature complement(371864..373423)
/gene="guaA"
/locus_tag="CGSHiEE_01965"
/note="GMP synthase; Reviewed; Region: guaA; PRK00074"
/db_xref="CDD:178842"
misc_feature complement(372845..373408)
/gene="guaA"
/locus_tag="CGSHiEE_01965"
/note="Type 1 glutamine amidotransferase (GATase1) domain
found in GMP synthetase; Region: GATase1_GMP_Synthase;
cd01742"
/db_xref="CDD:153213"
misc_feature complement(order(372896..372898,373013..373015,
373175..373180,373256..373264,373382..373387))
/gene="guaA"
/locus_tag="CGSHiEE_01965"
/note="AMP/PPi binding site [chemical binding]; other
site"
/db_xref="CDD:153213"
misc_feature complement(order(373175..373177,373259..373261))
/gene="guaA"
/locus_tag="CGSHiEE_01965"
/note="candidate oxyanion hole; other site"
/db_xref="CDD:153213"
misc_feature complement(order(372890..372892,372896..372898,
373178..373180))
/gene="guaA"
/locus_tag="CGSHiEE_01965"
/note="catalytic triad [active]"
/db_xref="CDD:153213"
misc_feature complement(order(372902..372904,373010..373012,
373166..373168))
/gene="guaA"
/locus_tag="CGSHiEE_01965"
/note="potential glutamine specificity residues [chemical
binding]; other site"
/db_xref="CDD:153213"
misc_feature complement(371867..372751)
/gene="guaA"
/locus_tag="CGSHiEE_01965"
/note="The C-terminal domain of GMP synthetase. It
contains two subdomains; the ATP pyrophosphatase domain
which closes to the N-termial and the dimerization domain
at C-terminal end. The ATP-PPase is a twisted,
five-stranded parallel beta-sheet sandwiched...; Region:
GMP_synthase_C; cd01997"
/db_xref="CDD:30184"
misc_feature complement(order(372197..372241,372257..372331,
372344..372373,372398..372400,372404..372448,
372464..372577,372608..372640,372644..372676,
372680..372751))
/gene="guaA"
/locus_tag="CGSHiEE_01965"
/note="ATP Binding subdomain [chemical binding]; other
site"
/db_xref="CDD:30184"
misc_feature complement(order(372296..372298,372659..372661,
372665..372667,372719..372730,372734..372742))
/gene="guaA"
/locus_tag="CGSHiEE_01965"
/note="Ligand Binding sites [chemical binding]; other
site"
/db_xref="CDD:30184"
misc_feature complement(order(371867..371935,371939..371965,
371984..372031,372041..372073,372080..372109,
372134..372172))
/gene="guaA"
/locus_tag="CGSHiEE_01965"
/note="Dimerization subdomain; other site"
/db_xref="CDD:30184"
gene complement(373542..375008)
/locus_tag="CGSHiEE_01970"
/db_xref="GeneID:5224995"
CDS complement(373542..375008)
/locus_tag="CGSHiEE_01970"
/EC_number="1.1.1.205"
/note="catalyzes the synthesis of xanthosine monophosphate
by the NAD+ dependent oxidation of inosine monophosphate"
/codon_start=1
/transl_table=11
/product="inosine 5'-monophosphate dehydrogenase"
/protein_id="YP_001290248.1"
/db_xref="GI:148825495"
/db_xref="GeneID:5224995"
/translation="MSLRIKQEALTFDDVLLVPAHSTVLPNTANLSTQLTKEIRLNIP
MLSAAMDTVTETKLAISLAQEGGIGFIHKNMTIERQADRVRKVKKFESGIVSEPVTVL
PNLTLAELAEMVKKNGFAGYPVVDEENNLIGIITGRDTRFVKDLSKTVSQVMTKKEDL
VTVKEGASREEILELMHQHRVEKVLVVNDSFKLKGMITVKDFQKAEQKPNACKDEFGR
LRVGAAVGAGAGNEERIDALVKAGVDVLLIDSSHGHSEGVLQRVRETRAKYPNLPIVA
GNVATAEGAIALADAGASAVKVGIGPGSICTTRIVTGVGVPQITAIADAAAALKDRGI
PVIADGGIRFSGDIAKAIAAGASCVMVGSMFAGTEEAPGEIELYQGRAFKSYRGMGSL
GAMAKGSSDRYFQSDNAADKLVPEGIEGRIPYKGYLKEIIHQQMGGLRSCMGLTGCAT
IDELRTKAEFVRISGAGIKESHVHDVAITKEAPNYRMG"
misc_feature complement(373545..375002)
/locus_tag="CGSHiEE_01970"
/note="inosine 5'-monophosphate dehydrogenase; Reviewed;
Region: PRK05567"
/db_xref="CDD:180134"
misc_feature complement(<374742..374984)
/locus_tag="CGSHiEE_01970"
/note="TIM barrel proteins share a structurally conserved
phosphate binding motif and in general share an eight
beta/alpha closed barrel structure. Specific for this
family is the conserved phosphate binding site at the
edges of strands 7 and 8. The phosphate...; Region:
TIM_phosphate_binding; cl09108"
/db_xref="CDD:213114"
misc_feature complement(374394..374726)
/locus_tag="CGSHiEE_01970"
/note="This cd contains two tandem repeats of the
cystathionine beta-synthase (CBS pair) domains in the
inosine 5' monophosphate dehydrogenase (IMPDH) protein.
IMPDH is an essential enzyme that catalyzes the first step
unique to GTP synthesis, playing a key...; Region:
CBS_pair_IMPDH; cd04601"
/db_xref="CDD:73101"
misc_feature complement(373620..>374360)
/locus_tag="CGSHiEE_01970"
/note="IMPDH: The catalytic domain of the inosine
monophosphate dehydrogenase. IMPDH catalyzes the
NAD-dependent oxidation of inosine 5'-monophosphate (IMP)
to xanthosine 5' monophosphate (XMP). It is a
rate-limiting step in the de novo synthesis of the
guanine...; Region: IMPDH; cd00381"
/db_xref="CDD:73364"
misc_feature complement(order(373758..373763,373839..373847,
373851..373853,373920..373925,373986..373988,
373992..373994,374091..374099))
/locus_tag="CGSHiEE_01970"
/note="active site"
/db_xref="CDD:73364"
gene 375138..376043
/locus_tag="CGSHiEE_01975"
/db_xref="GeneID:5224996"
CDS 375138..376043
/locus_tag="CGSHiEE_01975"
/EC_number="6.3.4.15"
/note="catalyzes the formation of biotinyl-5'-AMP, also
acts as a transcriptional repressor of the biotin operon"
/codon_start=1
/transl_table=11
/product="biotin--protein ligase"
/protein_id="YP_001290249.1"
/db_xref="GI:148825496"
/db_xref="GeneID:5224996"
/translation="MNFTLLTYLSDCQTKVRSELEKFSKNLEEDIQPLREIGLDILVD
GQHYRLVPMLPLLNPQQISTALFPYGIHYQPIISSTNEWILQNILSLKKGDLCVAEYQ
TAGRGRRGRQWLSPFAGQIMFSFYWAFDPKKSIEGLSLVIGLAIAEVLNVQVKWPNDI
LFDERKLGGILVEIANHKNGMLNLVIGIGINVSLSKQTEISQPYAEVCEIDPDVERQT
LLPKLIQHLYTRLNIFEQNGIDEEFQQAWQSYNAFSNSEVKVLTEQGVISGIEQGIDE
RGYLKVLCGNKIQMFNGGEVSLRKK"
misc_feature 375138..376040
/locus_tag="CGSHiEE_01975"
/note="bifunctional biotin--[acetyl-CoA-carboxylase]
synthetase/biotin operon repressor; Provisional; Region:
PRK11886"
/db_xref="CDD:183359"
misc_feature 375138..375335
/locus_tag="CGSHiEE_01975"
/note="Helix-turn-helix domains; Region: HTH; cl00088"
/db_xref="CDD:213080"
misc_feature 375354..375710
/locus_tag="CGSHiEE_01975"
/note="Biotin/lipoate A/B protein ligase family; Region:
BPL_LplA_LipB; pfam03099"
/db_xref="CDD:202534"
misc_feature 375894..376034
/locus_tag="CGSHiEE_01975"
/note="Biotin protein ligase C terminal domain; Region:
BPL_C; pfam02237"
/db_xref="CDD:111161"
gene 376402..377942
/locus_tag="CGSHiEE_r09322"
/db_xref="GeneID:5224764"
rRNA 376402..377942
/locus_tag="CGSHiEE_r09322"
/product="16S ribosomal RNA"
/db_xref="GeneID:5224764"
gene 378074..378149
/locus_tag="CGSHiEE_t09362"
/db_xref="GeneID:5542110"
tRNA 378074..378149
/locus_tag="CGSHiEE_t09362"
/product="tRNA-Glu"
/db_xref="GeneID:5542110"
gene 378423..381416
/locus_tag="CGSHiEE_r09334"
/db_xref="GeneID:5542154"
rRNA 378423..381416
/locus_tag="CGSHiEE_r09334"
/product="23S ribosomal RNA"
/db_xref="GeneID:5542154"
gene 381644..381763
/locus_tag="CGSHiEE_r09310"
/db_xref="GeneID:5224765"
rRNA 381644..381763
/locus_tag="CGSHiEE_r09310"
/product="5S ribosomal RNA"
/db_xref="GeneID:5224765"
gene 381938..382014
/locus_tag="CGSHiEE_t09364"
/db_xref="GeneID:5542122"
tRNA 381938..382014
/locus_tag="CGSHiEE_t09364"
/product="tRNA-Asp"
/db_xref="GeneID:5542122"
gene 382043..382118
/locus_tag="CGSHiEE_t09366"
/db_xref="GeneID:5542145"
tRNA 382043..382118
/locus_tag="CGSHiEE_t09366"
/product="tRNA-Trp"
/db_xref="GeneID:5542145"
gene 382320..382712
/locus_tag="CGSHiEE_01980"
/db_xref="GeneID:5224766"
CDS 382320..382712
/locus_tag="CGSHiEE_01980"
/note="COG3223 Predicted membrane protein"
/codon_start=1
/transl_table=11
/product="phosphate-starvation-inducible protein PsiE"
/protein_id="YP_001290250.1"
/db_xref="GI:148825497"
/db_xref="GeneID:5224766"
/translation="MPQIITDVLKIVLCTALIALAIVLIIALVKITYTLSMMVLNTSS
VVPYDVAEQAVMFFLYFGFIGLIVQYFKSGYHFPLRYFIYAGITAMLRLIIVNHESSV
DTILFAGAILIMVIALCLVLYSNKLKNI"
misc_feature 382323..382709
/locus_tag="CGSHiEE_01980"
/note="phosphate-starvation-inducible protein PsiE;
Provisional; Region: PRK02833"
/db_xref="CDD:179481"
gene complement(382776..384062)
/locus_tag="CGSHiEE_01985"
/db_xref="GeneID:5224738"
CDS complement(382776..384062)
/locus_tag="CGSHiEE_01985"
/note="COG3071 Uncharacterized enzyme of heme
biosynthesis"
/codon_start=1
/transl_table=11
/product="heme biosynthesis protein HemY"
/protein_id="YP_001290251.1"
/db_xref="GI:148825498"
/db_xref="GeneID:5224738"
/translation="MFRVLFLMLTLLVGLVAGPYISGQQGYVRIETANRIIEMSITTL
VIFFIISLAIIYAFEWGITRFFRLSRSSYQWFSNRKRVKAQKQTLEGLVKMNEGDYAK
AEKLIGKNAKHSAEPVLNLIKAAEAAQQRGDEFSANRYLIEATELAGSDNLLVEIART
RILLQQNKLPAARSSVDSLLEMARRNKEVLKLAVEIYLRSKAYQALDKILDNVANSGL
FNDEEFKDLRSKTENGLLDEKMNEEGIDGLLTWWNQQPRHRRNNIELKISLIQRLIDC
NDHESATELTFEILKKLGDNTAISLPLCTQITRLQPEDNSKLLKLIEKRAKRVDEKQK
CCINRALGYLYVRNNEFLKAADVFKNVIACPEQLEQNDLMMASYVFEQAGDKALAEQV
RQESLKSMMAIQDVIPESAEEKTEENSTALLESKSE"
misc_feature complement(382830..384062)
/locus_tag="CGSHiEE_01985"
/note="Uncharacterized enzyme of heme biosynthesis
[Coenzyme metabolism]; Region: HemY; COG3071"
/db_xref="CDD:32885"
misc_feature complement(383664..383987)
/locus_tag="CGSHiEE_01985"
/note="HemY protein N-terminus; Region: HemY_N; pfam07219"
/db_xref="CDD:191703"
gene complement(384073..385284)
/locus_tag="CGSHiEE_01990"
/db_xref="GeneID:5224741"
CDS complement(384073..385284)
/locus_tag="CGSHiEE_01990"
/note="COG2959 Uncharacterized enzyme of heme
biosynthesis"
/codon_start=1
/transl_table=11
/product="phosphate-starvation-inducible protein PsiE"
/protein_id="YP_001290252.1"
/db_xref="GI:148825499"
/db_xref="GeneID:5224741"
/translation="MAKEQPNDLTEQLTDTPKTAVEQAETMQSVPQTIVKKTGTALSL
LAILVALGIGGAGYYFGQQQIAEIQQKLTALENQTGANLSSNNTNNNKRLTQLELSLK
TAQENIAQLEQLIVSKTGEITSLQTQMKQVSQLAIAQQPSDWLFSEADFLLNNALRKL
VLDNDVDTAVSLLKLADETLVKVNNSQANEIRSAINQDLKQLLSLSSVDQNAIMQKLS
QLANTVDELQALNVNFDETSKNNDKLSNNITDWQQNIEKSATSFLNHFIRISPKQNSN
KKELLAPNQDIYLRENIRLRLQLAIMAVPRQQNELYKQSLEAVSSWVRSYFDTNAEVT
QNFLKLVDGLTDTSIYVDVPEQLKSLTLLDKYLNRTALDLQKVEIEADKAIDTMPKVE
AVKPTQSESQQ"
misc_feature complement(384076..385260)
/locus_tag="CGSHiEE_01990"
/note="Uncharacterized enzyme of heme biosynthesis
[Coenzyme metabolism]; Region: HemX; COG2959"
/db_xref="CDD:32779"
misc_feature complement(384190..385260)
/locus_tag="CGSHiEE_01990"
/note="putative uroporphyrinogen III C-methyltransferase;
Provisional; Region: PRK10920"
/db_xref="CDD:182839"
gene 385590..388121
/gene="cyaA"
/locus_tag="CGSHiEE_01995"
/db_xref="GeneID:5226273"
CDS 385590..388121
/gene="cyaA"
/locus_tag="CGSHiEE_01995"
/EC_number="4.6.1.1"
/note="catalyzes transfer of adenylyl group of ATP from
pyrophosphate to the 3'-hydroxyl group to form cyclic AMP"
/codon_start=1
/transl_table=11
/product="adenylate cyclase"
/protein_id="YP_001290253.1"
/db_xref="GI:148825500"
/db_xref="GeneID:5226273"
/translation="MECNLAQAKQWVSALDQRRFERALQGSGDAFQHVLAIAPLLLHL
NHPQLPGYVIHAPSGIANFLASDYQKKWLTNEYSIHYADHKPSTLKSAVNFHEVLPPI
LGVYVMGSFGSISQTSSSDLDTWICVRDGLSPDEYTLLTQKAKRISEWAMQFNVEINF
YLMDQQRFRNEHYADPLTIENSGSAQYMLLLDEFYRSAVRLAGKPLLWLHLWVENEKD
YEKQVARLITEGEIDPNDWVDFGGLGQFSANEYFGASLWHLYKGIDSPYKSVLKILLL
EAYSKEYPNTCLIARTFKRDLLSGNTNPDHHFDPYIAILAKVTQYLTALSEFKRLDFV
HRCFYVKATEDFARYQANNWRIRYMEILAQEWGWSAETVKHLNKRPFWKIKAVKENHD
NIMKFLMLSYRNLVEFARKHHIHSSVVPQDINILSRKLYTAFEELPGKVSLLNTQISH
NLSEAHLTFVEVRGNKHFKDGWYLINQPIHHIMFSKERVIEYGESLNKLVSWAYFNHL
LTEKTELSIFSKNVTLSTLQRFVTNLRQSFPSTIAKQPKNSDLLNQCEIRSLFIAINL
TTDPTSKVEEVLTGISSRDLFSFGSLEQSLVGSIDFTYRNVWNEIRTLHFEGQNAILL
ALKVLSNKIYRGVNRLDSIQVYCYSERYRQDLRQLVMGLVNRCVSIQVGDIQQPCQTS
RLRVAGKNWQLFFEDRGISLQEIGNESVCNDAESAVDFDEVLQTPIEDGETNQESRRY
PPEMDAFASEGFLQFFFEDNSDHSFNVYILDESNHLEIYRHCDGEKDEKVREINQLYQ
NAKQEGDKNPYNIVQHNFNYPQFYQLQNGKNGISIVPFKFRQMNK"
misc_feature 385590..388118
/gene="cyaA"
/locus_tag="CGSHiEE_01995"
/note="Adenylate cyclase [Nucleotide transport and
metabolism]; Region: CyaA; COG3072"
/db_xref="CDD:32886"
misc_feature 385590..386216
/gene="cyaA"
/locus_tag="CGSHiEE_01995"
/note="Adenylate cyclase NT domain; Region: Adenyl_cycl_N;
pfam12633"
/db_xref="CDD:204990"
misc_feature 386295..388118
/gene="cyaA"
/locus_tag="CGSHiEE_01995"
/note="Adenylate cyclase, class-I; Region: Adenylate_cycl;
pfam01295"
/db_xref="CDD:189931"
gene 388195..389202
/gene="gpsA"
/locus_tag="CGSHiEE_02000"
/db_xref="GeneID:5226274"
CDS 388195..389202
/gene="gpsA"
/locus_tag="CGSHiEE_02000"
/EC_number="1.1.1.94"
/note="catalyzes the NAD(P)H-dependent reduction of
glycerol 3-phosphate to glycerone phosphate"
/codon_start=1
/transl_table=11
/product="NAD(P)H-dependent glycerol-3-phosphate
dehydrogenase"
/protein_id="YP_001290254.1"
/db_xref="GI:148825501"
/db_xref="GeneID:5226274"
/translation="MITSQTPITVLGAGSYGTALAITFSRNGSPTHLWGHNPVHIAQM
QTERQNYRFLPDVIFPEDLHLESNLAQAMEYSQDILIVVPSHAFGEILIKIKPHLKAH
HRLIWATKGLERNTGRLLQTVVEEQLGTQYPLAVLSGPTFAKELAQGLPSAITLAANN
EQFAREFQSRIHCSKGFRVYINSDMTGVQLGGAIKNVIAIGAGISDGMGFGANARTAL
ITRGIAEITRLGISLGANTNTFMGMSGLGDLVLTCTDNQSRNRRFGLMLGKGLDAQMA
MENIGQVVEGFYNTKEAYLLAQRQGVEMPITEQIYQMLFCGKNAQDVAISLLGRACKG
E"
misc_feature 388207..389184
/gene="gpsA"
/locus_tag="CGSHiEE_02000"
/note="NAD(P)H-dependent glycerol-3-phosphate
dehydrogenase; Validated; Region: gpsA; PRK00094"
/db_xref="CDD:178859"
misc_feature 388213..388686
/gene="gpsA"
/locus_tag="CGSHiEE_02000"
/note="NAD-dependent glycerol-3-phosphate dehydrogenase
N-terminus; Region: NAD_Gly3P_dh_N; pfam01210"
/db_xref="CDD:201664"
misc_feature 388741..389175
/gene="gpsA"
/locus_tag="CGSHiEE_02000"
/note="NAD-dependent glycerol-3-phosphate dehydrogenase
C-terminus; Region: NAD_Gly3P_dh_C; pfam07479"
/db_xref="CDD:116100"
gene 389219..390022
/gene="cysE"
/locus_tag="CGSHiEE_02005"
/db_xref="GeneID:5226275"
CDS 389219..390022
/gene="cysE"
/locus_tag="CGSHiEE_02005"
/EC_number="2.3.1.30"
/note="catalyzes the O-acetylation of serine"
/codon_start=1
/transl_table=11
/product="serine acetyltransferase"
/protein_id="YP_001290255.1"
/db_xref="GI:148825502"
/db_xref="GeneID:5226275"
/translation="MTLDVWQHIRQEAKELAENEPMLASFFHSTILKHQNLGGALSYL
LANKLANPIMPAISLREIIEEAYQSNPSIIDCAACDIQAVRHRDPAVELWSTPLLYLK
GFHAIQSYRITHYLWNQNRKSLALYLQNQISVAFDVDIHPAAKIGHGIMFDHATGIVV
GETSVIENDVSILQGVTLGGTGKESGDRHPKVREGVMIGAGAKILGNIEVGKYAKIGA
NSVVLNPVPEYATAAGVPARIVSQDKAAKPAFDMNQYFIGIDDGMNLNI"
misc_feature 389219..390010
/gene="cysE"
/locus_tag="CGSHiEE_02005"
/note="serine acetyltransferase; Provisional; Region:
cysE; PRK11132"
/db_xref="CDD:182987"
misc_feature 389231..389545
/gene="cysE"
/locus_tag="CGSHiEE_02005"
/note="Serine acetyltransferase, N-terminal; Region:
SATase_N; pfam06426"
/db_xref="CDD:191519"
misc_feature 389624..389926
/gene="cysE"
/locus_tag="CGSHiEE_02005"
/note="Serine acetyltransferase (SAT): SAT catalyzes the
CoA-dependent acetylation of the side chain hydroxyl group
of L-serine to form O-acetylserine, as the first step of a
two-step biosynthetic pathway in bacteria and plants
leading to the formation of...; Region: LbH_SAT; cd03354"
/db_xref="CDD:100045"
misc_feature order(389627..389629,389633..389635,389678..389680,
389780..389782,389870..389872,389879..389881,
389885..389887)
/gene="cysE"
/locus_tag="CGSHiEE_02005"
/note="trimer interface [polypeptide binding]; other site"
/db_xref="CDD:100045"
misc_feature order(389675..389680,389735..389740,389756..389761,
389780..389785,389816..389818,389861..389863,
389867..389872,389879..389881,389885..389887,
389909..389911,389924..389926)
/gene="cysE"
/locus_tag="CGSHiEE_02005"
/note="active site"
/db_xref="CDD:100045"
misc_feature order(389675..389680,389756..389758,389780..389785)
/gene="cysE"
/locus_tag="CGSHiEE_02005"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:100045"
misc_feature order(389735..389740,389756..389761,389816..389818,
389861..389863,389867..389872,389879..389881,
389885..389887,389909..389911,389924..389926)
/gene="cysE"
/locus_tag="CGSHiEE_02005"
/note="CoA binding site [chemical binding]; other site"
/db_xref="CDD:100045"
gene 390032..390847
/locus_tag="CGSHiEE_02010"
/db_xref="GeneID:5226276"
CDS 390032..390847
/locus_tag="CGSHiEE_02010"
/EC_number="1.1.1.25"
/note="catalyzes the conversion of shikimate to
3-dehydroshikimate"
/codon_start=1
/transl_table=11
/product="shikimate 5-dehydrogenase"
/protein_id="YP_001290256.1"
/db_xref="GI:148825503"
/db_xref="GeneID:5226276"
/translation="MINKDTQLCMSLSGRPSNFGTTFHNYLYDKLGLNFIYKAFTTQD
IEHAIKGVRALGIRGCAVSMPFKETCMPFLDEIHPSAQAIESVNTIVNDNGFLRAYNT
DYIAIVKLIEKYHLNKNAKVIVHGSGGMAKAVVAAFKNSGFEKLKIYARNVKTGQYLA
ALYGYAYINSLENQQADILVNVTPIGMKGGKEEMDLAFPKAFIDNASVAFDVVAMPVE
TPFIRYAQARGKQTISGAEVIVLQAVEQFELYTHQRPSDELIAEAAAFARTKF"
misc_feature 390032..390838
/locus_tag="CGSHiEE_02010"
/note="shikimate 5-dehydrogenase; Reviewed; Region:
PRK12550"
/db_xref="CDD:183587"
misc_feature 390101..390301
/locus_tag="CGSHiEE_02010"
/note="Shikimate dehydrogenase substrate binding domain;
Region: Shikimate_dh_N; pfam08501"
/db_xref="CDD:149523"
misc_feature 390335..390787
/locus_tag="CGSHiEE_02010"
/note="NAD(P) binding domain of Shikimate dehydrogenase;
Region: NAD_bind_Shikimate_DH; cd01065"
/db_xref="CDD:133443"
misc_feature order(390338..390340,390671..390673,390746..390748,
390755..390757)
/locus_tag="CGSHiEE_02010"
/note="shikimate binding site; other site"
/db_xref="CDD:133443"
misc_feature order(390410..390412,390419..390421,390479..390484,
390575..390583,390665..390667,390734..390736,
390743..390748)
/locus_tag="CGSHiEE_02010"
/note="NAD(P) binding site [chemical binding]; other site"
/db_xref="CDD:133443"
gene 390985..392370
/locus_tag="CGSHiEE_02015"
/db_xref="GeneID:5226277"
CDS 390985..392370
/locus_tag="CGSHiEE_02015"
/note="COG0471 Di- and tricarboxylate transporters"
/codon_start=1
/transl_table=11
/product="putative di- and tricarboxylate transporter"
/protein_id="YP_001290257.1"
/db_xref="GI:148825504"
/db_xref="GeneID:5226277"
/translation="MGEMASLRSHKNGIIFILDIVLFFVLLNVLPFEPKANSGLALLA
FIAVLWLSEALHVTITALLVPLLAVALGLVSTKQALVGFADPTIFLFFGGFSLATALH
IQKLDKLIANKIMALACGNLFIAVIYLFLITAFLSMWMSNTATAAMMLPLAMGILSQL
DREKDHNTYVFVLLGIAYSASIGGMGTLVGSPPNAIVASNLNLTFSDWLWYGLPIMII
LLPLMIGILYIIFKPKLHLNFEQTFENIEMNPMRILTFIIFSVIALTWIFSGKINPFI
SGLLGLQKNIASFDSIVALLAAIVICSTGVASWKQIQSNTDWGVLMLFGGGLTLSAVL
KDSGASKILADSIVFMIDGQHFYLIGLLVAAFIIFLTEFTSNTASAALLVPIFISIAQ
SLGMPEIGLALIIGIGASCAFMLPVATPPNAIVFGSGQVKQSEMVKVGFLLNLVCVVV
IATMGYMFWLK"
misc_feature 391102..392364
/locus_tag="CGSHiEE_02015"
/note="Di- and tricarboxylate transporters [Inorganic ion
transport and metabolism]; Region: CitT; COG0471"
/db_xref="CDD:30819"
misc_feature 391102..392361
/locus_tag="CGSHiEE_02015"
/note="Permease SLC13 (solute carrier 13). The
sodium/dicarboxylate cotransporter NaDC-1 has been shown
to translocate Krebs cycle intermediates such as
succinate, citrate, and alpha-ketoglutarate across plasma
membranes rabbit, human, and rat kidney. It is...; Region:
SLC13_permease; cd01115"
/db_xref="CDD:73247"
misc_feature order(391123..391134,391153..391194,391237..391290,
391360..391410,391414..391467,391492..391563,
391729..391773,391798..391836,391858..391893,
391930..391986,392059..392106,392158..392217,
392305..392343)
/locus_tag="CGSHiEE_02015"
/note="transmembrane helices; other site"
/db_xref="CDD:73247"
gene complement(392508..393356)
/locus_tag="CGSHiEE_02020"
/db_xref="GeneID:5226278"
CDS complement(392508..393356)
/locus_tag="CGSHiEE_02020"
/note="catalyzes the formation of
5,10-methenyltetrahydrofolate from
5,10-methylenetetrahydrofolate and subsequent formation of
10-formyltetrahydrofolate from
5,10-methenyltetrahydrofolate"
/codon_start=1
/transl_table=11
/product="bifunctional 5,10-methylene-tetrahydrofolate
dehydrogenase/ 5,10-methylene-tetrahydrofolate
cyclohydrolase"
/protein_id="YP_001290258.1"
/db_xref="GI:148825505"
/db_xref="GeneID:5226278"
/translation="MAAKIISGTELSKQIKANLADKITHYIEQGKRAPGLAVILVGAD
PASQIYVGNKRKSCEEVGILSKSYDLPETTTQNELLAIIDQLNADKNIDGILVQLPLP
KQINAEAIIERIDPKKDVDGFHPYNVGRLCQRIPTLRACTPYGVMKLLETTGIDLHGK
HAVIVGASNIVGRPMSLELLLAGATVTVTHRFTKNLENHVRQADILVVAVGKPNLISG
DWIKESAVVIDVGINRVDGKLVGDVEFDKAAEKAAYITPVPGGVGPMTVAMLMSNTLY
AYEHNK"
misc_feature complement(392517..393356)
/locus_tag="CGSHiEE_02020"
/note="bifunctional 5,10-methylene-tetrahydrofolate
dehydrogenase/ 5,10-methylene-tetrahydrofolate
cyclohydrolase; Provisional; Region: PRK10792"
/db_xref="CDD:182735"
misc_feature complement(392994..393347)
/locus_tag="CGSHiEE_02020"
/note="Tetrahydrofolate dehydrogenase/cyclohydrolase,
catalytic domain; Region: THF_DHG_CYH; pfam00763"
/db_xref="CDD:201431"
misc_feature complement(392520..393011)
/locus_tag="CGSHiEE_02020"
/note="NADP binding domain of methylene-tetrahydrofolate
dehydrogenase/cyclohydrolase; Region:
NAD_bind_m-THF_DH_Cyclohyd; cd01080"
/db_xref="CDD:133448"
misc_feature complement(order(392751..392753,392778..392783,
392787..392789,392793..392810,392817..392819,
392826..392831,392856..392858,392874..392876,
392880..392882,392970..392972,392979..392984))
/locus_tag="CGSHiEE_02020"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:133448"
misc_feature complement(order(392559..392561,392568..392570,
392661..392663,392667..392669,392712..392714,
392721..392723,392727..392729,392784..392789,
392853..392858,392931..392933))
/locus_tag="CGSHiEE_02020"
/note="NADP binding site [chemical binding]; other site"
/db_xref="CDD:133448"
misc_feature complement(order(392556..392558,392577..392582))
/locus_tag="CGSHiEE_02020"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:133448"
gene 393538..393614
/locus_tag="CGSHiEE_t09368"
/db_xref="GeneID:5542101"
tRNA 393538..393614
/locus_tag="CGSHiEE_t09368"
/product="tRNA-Pro"
/db_xref="GeneID:5542101"
gene 393662..393738
/locus_tag="CGSHiEE_t09370"
/db_xref="GeneID:5542152"
tRNA 393662..393738
/locus_tag="CGSHiEE_t09370"
/product="tRNA-Arg"
/db_xref="GeneID:5542152"
misc_feature complement(393884..395172)
/note="potential frameshift: common BLAST hit:
gi|68249309|ref|YP_248421.1| L-fucose permease
[Haemophilus influenzae 86-028NP]"
gene complement(395211..395861)
/locus_tag="CGSHiEE_02035"
/db_xref="GeneID:5225327"
CDS complement(395211..395861)
/locus_tag="CGSHiEE_02035"
/EC_number="4.1.2.17"
/note="catalyzes the formation of glycerone phosphate and
(S)-lactaldehyde from L-fuculose 1-phosphate"
/codon_start=1
/transl_table=11
/product="L-fuculose phosphate aldolase"
/protein_id="YP_001290259.1"
/db_xref="GI:148825506"
/db_xref="GeneID:5225327"
/translation="MNRAELSQKIIDTCLEMTKLGLNQGTAGNVSVRYKDGMLITPTG
MPYHLMKTENIVYVDGNGKHEENKLPSSEWQFHLSVYHTRPEANAVVHNHSIHCAGLS
ILEKPIPAIHYMVAVSGTDHIPCVPYATFGSHELASYVATGIKESKAILLAHHGLITC
GENLDKALWLAQEVEVLASWYLKLLSTGLEIPLLSKEQMQVVLGKFHTYGLRIEES"
misc_feature complement(395241..395852)
/locus_tag="CGSHiEE_02035"
/note="Class II Aldolase and Adducin head (N-terminal)
domain. Aldolases are ubiquitous enzymes catalyzing
central steps of carbohydrate metabolism. Based on
enzymatic mechanisms, this superfamily has been divided
into two distinct classes (Class I and II); Region:
Aldolase_II; cd00398"
/db_xref="CDD:29521"
misc_feature complement(order(395253..395255,395313..395315,
395334..395336,395346..395348,395367..395369,
395400..395402,395478..395480,395520..395525,
395529..395531,395550..395558,395571..395576,
395580..395582,395715..395720,395724..395726,
395790..395792,395814..395816,395826..395828))
/locus_tag="CGSHiEE_02035"
/note="intersubunit interface [polypeptide binding]; other
site"
/db_xref="CDD:29521"
misc_feature complement(order(395397..395399,395580..395582,
395586..395588,395643..395651,395730..395735,
395775..395777))
/locus_tag="CGSHiEE_02035"
/note="active site"
/db_xref="CDD:29521"
misc_feature complement(order(395397..395399,395580..395582,
395586..395588))
/locus_tag="CGSHiEE_02035"
/note="Zn2+ binding site [ion binding]; other site"
/db_xref="CDD:29521"
gene complement(395881..396315)
/locus_tag="CGSHiEE_02040"
/db_xref="GeneID:5225328"
CDS complement(395881..396315)
/locus_tag="CGSHiEE_02040"
/EC_number="4.1.2.17"
/note="COG4154 Fucose dissimilation pathway protein FucU"
/codon_start=1
/transl_table=11
/product="L-fuculose phosphate aldolase"
/protein_id="YP_001290260.1"
/db_xref="GI:148825507"
/db_xref="GeneID:5225328"
/translation="MLKGIHPALSPELLKTLAEMGHGDEIVLADTHFPAHSLHKNVIR
ADGISIDILLEAITPLFEFDAYVDAPLLMMKAVEGDSLDPNVETRYLNAIESAVGFTP
NLTCLERFDFYTRAKQAYAVVVSGEIAKYGNIIIKKGVTPIL"
misc_feature complement(395884..396315)
/locus_tag="CGSHiEE_02040"
/note="Fucose dissimilation pathway protein FucU
[Carbohydrate transport and metabolism]; Region: FucU;
COG4154"
/db_xref="CDD:33904"
gene complement(396330..397742)
/locus_tag="CGSHiEE_02045"
/db_xref="GeneID:5225329"
CDS complement(396330..397742)
/locus_tag="CGSHiEE_02045"
/note="COG1070 Sugar (pentulose and hexulose) kinases"
/codon_start=1
/transl_table=11
/product="L-fuculokinase"
/protein_id="YP_001290261.1"
/db_xref="GI:148825508"
/db_xref="GeneID:5225329"
/translation="MVIALIFDCGATNLRTIAINEKGQILASHHLANNTKQGIESSDY
HIWDIEEIWQKLTSCATQTFNQLMQQGIDLKDIVGISVTTFGVDGAPFDENDQQLYPI
ISWKCPRTIPVMENLSNQLDIKSLYQRNGIGQYSFNTLFKLHWLKTHKPDVFRKMAKF
VFISSMLTQRLTGQFTTDHTMAGTSMMTNLTSGNWDPSILASLGLSNNHFPPMRYAGK
KVGKLRTPLAQKWGLNPVPVISCGHDTQFAVFGSGAGLNQPVLSSGTWEILMARTQHA
EPRFEFVSQGLTTEFDAQSNCFNPAVQWVGSGVIEWLGKLLFSDVYGSDHYYTTMIKE
GEQAFNAGKSAVNFEGIFSQLGQGNISGLSMFATRGEIYVSALQHMANQLKNGLSVLQ
QVSQFQAKSLICVGGGSKNVLWNQIRANTLNLPIDVVDIAESTVLGAAMFTFAGVGIY
ENVNAAQQAMQPTRKRIYPN"
misc_feature complement(396333..397736)
/locus_tag="CGSHiEE_02045"
/note="L-fuculokinase; Region: fuculo_kin_coli; TIGR02628"
/db_xref="CDD:131676"
misc_feature complement(396384..397736)
/locus_tag="CGSHiEE_02045"
/note="Nucleotide-Binding Domain of the sugar
kinase/HSP70/actin superfamily; Region:
NBD_sugar-kinase_HSP70_actin; cl17037"
/db_xref="CDD:213144"
misc_feature complement(order(396525..396527,396948..396959,
397011..397013,397698..397700,397704..397706,
397710..397721))
/locus_tag="CGSHiEE_02045"
/note="nucleotide binding site [chemical binding]; other
site"
/db_xref="CDD:212657"
gene complement(397815..399584)
/gene="fucI"
/locus_tag="CGSHiEE_02050"
/db_xref="GeneID:5225330"
CDS complement(397815..399584)
/gene="fucI"
/locus_tag="CGSHiEE_02050"
/EC_number="5.3.1.25"
/note="catalyzes the conversion of the aldose L-fucose
into the corresponding ketose L-fuculose"
/codon_start=1
/transl_table=11
/product="L-fucose isomerase"
/protein_id="YP_001290262.1"
/db_xref="GI:148825509"
/db_xref="GeneID:5225330"
/translation="MALATQSNRIKIGIRPTIDGRRMGVRESLETQTIRMAQSVAQLL
QTHIRYTDSTFVECVVADSTIGGVAEAAACADKFKRENVGLTITVTPCWCYGSETIDM
DPHMPKAIWGFNGTERPGAVYLAAALAGHSQLGLPAFSIYGTEVQEADDTNIPEDVKE
KLLRFARAGLAVASIRGKSYLSIGSVSMGIAGSIVNQAFFQEYLGMRNEYVDMMEIKR
RLDRKIYDQEEVDLALSWVKQYCKEGVDVNSLENQRNAEERAELWENVVKMTIITRDL
MVGNPKLATLNYAEEALGHNAIAAGFQGQRHWTDHLPNGDFMEAMLNSTYDWNGVRPP
YILATENDSLNAIGMLFGHQLTGKAQIFADVRTYWSQDSVERVTGWRPESGFIHLINS
GSAALDGTGEHQDAQGNPTLKPAWDVTEEEAKRCLENTRWCPAVHEYFRGGGLSSQFL
TKGGIPFTMHRINLIKGLGPVLQIAEGWSIDLPQDVHNKLNQRTNETWPTTWFVPRLT
GKGAFTDVYSVMANWGANHCVATHGHVGADLITLASMLRIPVCMHNVSEKNIFRPSAW
NGFGQDKEGQDYRACQNFGPLYK"
misc_feature complement(397818..399569)
/gene="fucI"
/locus_tag="CGSHiEE_02050"
/note="L-fucose isomerase; Provisional; Region: fucI;
PRK10991"
/db_xref="CDD:182885"
misc_feature complement(397818..399554)
/gene="fucI"
/locus_tag="CGSHiEE_02050"
/note="L-fucose isomerase (FucIase) and L-arabinose
isomerase (AI) family; composed of FucIase, AI and similar
proteins. FucIase converts L-fucose, an aldohexose, to its
ketose form, which prepares it for aldol cleavage (similar
to the isomerization of glucose...; Region:
L-fuc_L-ara-isomerases; cl00947"
/db_xref="CDD:207257"
misc_feature complement(order(398664..398669,398697..398699,
398931..398933,398943..398963,398982..398984,
398991..398993,399027..399029,399048..399050,
399180..399185,399291..399293,399348..399350,
399357..399359,399369..399371))
/gene="fucI"
/locus_tag="CGSHiEE_02050"
/note="hexamer (dimer of trimers) interface [polypeptide
binding]; other site"
/db_xref="CDD:73216"
misc_feature complement(order(397932..397934,398013..398015,
398025..398027,398034..398036,398193..398195,
398475..398477,398481..398483,398487..398489,
398667..398672,399012..399014,399018..399023,
399102..399104,399150..399155,399159..399161,
399186..399191,399198..399200,399294..399302,
399306..399308))
/gene="fucI"
/locus_tag="CGSHiEE_02050"
/note="trimer interface [polypeptide binding]; other site"
/db_xref="CDD:73216"
misc_feature complement(order(398004..398009,398493..398495,
398565..398567,398670..398672,399306..399308))
/gene="fucI"
/locus_tag="CGSHiEE_02050"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:73216"
misc_feature complement(order(398004..398006,398493..398495,
398565..398567))
/gene="fucI"
/locus_tag="CGSHiEE_02050"
/note="Mn binding site [ion binding]; other site"
/db_xref="CDD:73216"
gene complement(399814..400563)
/gene="fucI"
/locus_tag="CGSHiEE_02055"
/db_xref="GeneID:5225244"
CDS complement(399814..400563)
/gene="fucI"
/locus_tag="CGSHiEE_02055"
/EC_number="5.3.1.25"
/note="COG1349 Transcriptional regulators of sugar
metabolism"
/codon_start=1
/transl_table=11
/product="L-fucose isomerase"
/protein_id="YP_001290263.1"
/db_xref="GI:148825510"
/db_xref="GeneID:5225244"
/translation="MNYRDELILQWVNQQGKASVIELAQHCDISVETIRRDLNKLANK
GLLHRTHGGAVSNKTKDLGSFFQTRKHINATAKRHIAQKALDLLYENAVIGLDASSTS
WYFAYLMPDIPCTVVTNSMFNINALVNKSNVKTIVTGGVYSAKYEAFYGPLSEYLLQR
LHINFSVFSCSGIDKNGNIWESNELNASLKRKMMEASERAYLLIDSSKFEKTSLIQLA
DLNKINTIFSDRSLPDNLQKYCEQHDIMTVL"
misc_feature complement(399817..400563)
/gene="fucI"
/locus_tag="CGSHiEE_02055"
/note="Transcriptional regulators of sugar metabolism
[Transcription / Carbohydrate transport and metabolism];
Region: GlpR; COG1349"
/db_xref="CDD:31540"
misc_feature complement(400384..400554)
/gene="fucI"
/locus_tag="CGSHiEE_02055"
/note="DeoR-like helix-turn-helix domain; Region:
HTH_DeoR; pfam08220"
/db_xref="CDD:116806"
misc_feature complement(399871..400350)
/gene="fucI"
/locus_tag="CGSHiEE_02055"
/note="DeoR C terminal sensor domain; Region: DeoRC;
pfam00455"
/db_xref="CDD:201239"
gene 400761..403532
/locus_tag="CGSHiEE_02060"
/db_xref="GeneID:5225245"
CDS 400761..403532
/locus_tag="CGSHiEE_02060"
/note="transcription regulator that activates
transcription by stimulating RNA polymerase (RNAP)
recycling in case of stress conditions such as supercoiled
DNA or high salt concentrations. Probably acts by
releasing the RNAP, when it is trapped or immobilized on
tightly supercoiled DNA"
/codon_start=1
/transl_table=11
/product="ATP-dependent helicase HepA"
/protein_id="YP_001290264.1"
/db_xref="GI:148825511"
/db_xref="GeneID:5225245"
/translation="MPFAIGQRWLSESENALGLGVITALDQRTVTIYFPAADETRIYA
IAQAPLSRIVFSKGETLSHQAGWQGEILDVQNMNGLLFYLVKNPQDEDVIVQERDISP
IISFSQAKDRLFSAQIDRSTHFALRYRTLCHQQAQFKSPLRGLRGTRAGLIPHQLHIA
AEVGNRVNPRVLLADEVGLGKTIEAGMILQNQLFAEKVQRVLIIVPETLQHQWLVEML
RRFNLHFALFDEERCNDFDLDAVNPFTTESLIICSLNWLETHPNRVEQALDAQFDCLI
VDEAHHLVWSETSPSAAYLFVEQLARIIPSVLLLTATPEQLGQESHFARLRLLDPERF
FDYQTFVKEQEHYQPVVNAVESLLANKALSAVEKNHISDLLLEQDVEPLFKAIASNND
EEQQRARQELIQALIDRHGTGRMLFRNTRQGVKGFPHRVYHQITLSEENDKIDWLIDF
LKLHRDEKIFVICQTAATAIQLEQILREREAIRAAVFHEKMSIIERDRAAAYFADLEN
GAQVLLSSSIGSEGRNFQFAANLVLFDLPTNPDLLEQCIGRLDRIGQKRDVQIYMPCA
KDSPQSRLARWYNEGLNAFEQTCPMGMALFSQFADELEKVRSNSTALSENEFSGLLKQ
TKTAREKLKIELEKGRDRLLELNSHGGEQAQALADQIADEDNSPELVNFALKLFDIIG
VEQEDLGANSIVISPTGTMLVPDFPGLKEEGVTVTFDRELALAREEMEFLTWDHPMIR
QGIDLVASGDIGKAAMALLVNKQLPAGTLLIELIYVVESQSPKGLQLNRFLPPTPIRL
LLDNKGNNMGEQVAFETLHSKLKPLGKNIANQMVKMARSNIESLITRGDQLVKSLAEP
IIAEAKNQADQQLSAEINRLQALRAVNKNIRQSEIDILEQQRTQSLDELSKANWRLDC
LRVIVTNKE"
misc_feature 400764..403523
/locus_tag="CGSHiEE_02060"
/note="ATP-dependent helicase HepA; Validated; Region:
PRK04914"
/db_xref="CDD:179891"
misc_feature 401271..401702
/locus_tag="CGSHiEE_02060"
/note="DEAD-like helicases superfamily. A diverse family
of proteins involved in ATP-dependent RNA or DNA
unwinding. This domain contains the ATP-binding region;
Region: DEXDc; cd00046"
/db_xref="CDD:28927"
misc_feature 401292..401306
/locus_tag="CGSHiEE_02060"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:28927"
misc_feature 401592..401603
/locus_tag="CGSHiEE_02060"
/note="putative Mg++ binding site [ion binding]; other
site"
/db_xref="CDD:28927"
misc_feature 402057..402446
/locus_tag="CGSHiEE_02060"
/note="Helicase superfamily c-terminal domain; associated
with DEXDc-, DEAD-, and DEAH-box proteins, yeast
initiation factor 4A, Ski2p, and Hepatitis C virus NS3
helicases; this domain is found in a wide variety of
helicases and helicase related proteins; may...; Region:
HELICc; cd00079"
/db_xref="CDD:28960"
misc_feature order(402150..402161,402222..402227,402306..402314)
/locus_tag="CGSHiEE_02060"
/note="nucleotide binding region [chemical binding]; other
site"
/db_xref="CDD:28960"
misc_feature order(402330..402332,402393..402395,402405..402407,
402414..402416)
/locus_tag="CGSHiEE_02060"
/note="ATP-binding site [chemical binding]; other site"
/db_xref="CDD:28960"
gene 403535..404194
/locus_tag="CGSHiEE_02065"
/db_xref="GeneID:5225203"
CDS 403535..404194
/locus_tag="CGSHiEE_02065"
/note="COG0564 Pseudouridylate synthases, 23S
RNA-specific"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290265.1"
/db_xref="GI:148825512"
/db_xref="GeneID:5225203"
/translation="MALIEYNPPLEPYLDIIYQDNHLCVVNKPSGLLSVPGNQPQYYD
SAMSRVKEKFGFCEPAHRLDMATSGIIVFALSKAADRELKRQFREREPKKHYQAIVWG
HLENDYGEVNLPMICDWENRPRQRLDFVLGKRAVTKFEVLARLPNNSTRVKLTPVTGR
SHQLRLHMLALGHPILGDKFYSHPQAKAMSPRLCLHAEELTITHPITGETMTFNAKSD
F"
misc_feature <403559..404191
/locus_tag="CGSHiEE_02065"
/note="Pseudouridylate synthases, 23S RNA-specific
[Translation, ribosomal structure and biogenesis]; Region:
RluA; COG0564"
/db_xref="CDD:30910"
misc_feature 403607..404140
/locus_tag="CGSHiEE_02065"
/note="Pseudouridine synthase, RsuA/RluD family; Region:
PseudoU_synth_RluCD_like; cd02869"
/db_xref="CDD:211346"
misc_feature order(403715..403726,404027..404029)
/locus_tag="CGSHiEE_02065"
/note="active site"
/db_xref="CDD:211346"
gene 404221..404799
/locus_tag="CGSHiEE_02070"
/db_xref="GeneID:5225204"
CDS 404221..404799
/locus_tag="CGSHiEE_02070"
/note="COG0705 Uncharacterized membrane protein (homolog
of Drosophila rhomboid)"
/codon_start=1
/transl_table=11
/product="glp protein"
/protein_id="YP_001290266.1"
/db_xref="GI:148825513"
/db_xref="GeneID:5225204"
/translation="MKKFLAQQGKITLILTALCALIYLAQQLGFEDDIMYLMHYPAYE
EQDSEVWRYISHTLVHLSNLHILFNLSWFFIFGGMIERTFGSVKLLMLYVVASAITGY
VQNYVSGPAFFGLSGVVYAVLGYVFIRDKLNHHLFDLPEGFFTMLLVGIALGFISPLF
GVEMGNAAHISGLIVGLIWGFIDSKLCKNSLE"
misc_feature 404356..404775
/locus_tag="CGSHiEE_02070"
/note="Rhomboid family; Region: Rhomboid; pfam01694"
/db_xref="CDD:201925"
gene 404829..405596
/locus_tag="CGSHiEE_02075"
/db_xref="GeneID:5225205"
CDS 404829..405596
/locus_tag="CGSHiEE_02075"
/note="COG1349 Transcriptional regulators of sugar
metabolism"
/codon_start=1
/transl_table=11
/product="glycerol-3-phosphate regulon repressor"
/protein_id="YP_001290267.1"
/db_xref="GI:148825514"
/db_xref="GeneID:5225205"
/translation="MKQSLRHQKIIKLVGQSGYLSTEELVAALDVSPQTIRRDLNILA
ELDLIRRHHGGAASPSSAENSDYVDRKQFFSLQKNNIAKEVAKLIPNGASLFIDIGTT
PEAVANALLGHEKLRIVTNNLNAAHLLRQNESFDIVMAGGSLRMDGGIIGEATVNFIS
QFRLDFGILGISAIDADGSLLDYDYHEVQVKRAIIESSRQTLLVTDHSKFSRQAIVRL
GELSDVEYLFTDDVPEGIVNYLKAQKTKLVLCNGKVR"
misc_feature 404829..405578
/locus_tag="CGSHiEE_02075"
/note="DNA-binding transcriptional repressor GlpR;
Provisional; Region: PRK10906"
/db_xref="CDD:182827"
misc_feature 404844..405011
/locus_tag="CGSHiEE_02075"
/note="DeoR-like helix-turn-helix domain; Region:
HTH_DeoR; pfam08220"
/db_xref="CDD:116806"
misc_feature 404922..404966
/locus_tag="CGSHiEE_02075"
/note="putative DNA binding helix; other site"
/db_xref="CDD:133478"
misc_feature 405057..405521
/locus_tag="CGSHiEE_02075"
/note="DeoR C terminal sensor domain; Region: DeoRC;
pfam00455"
/db_xref="CDD:201239"
gene complement(405898..406719)
/locus_tag="CGSHiEE_02080"
/db_xref="GeneID:5225206"
CDS complement(405898..406719)
/locus_tag="CGSHiEE_02080"
/note="COG1464 ABC-type metal ion transport system,
periplasmic component/surface antigen"
/codon_start=1
/transl_table=11
/product="putative D-methionine-binding lipoprotein MetQ"
/protein_id="YP_001290268.1"
/db_xref="GI:148825515"
/db_xref="GeneID:5225206"
/translation="MKLKQLFAITAIASALVLTGCKEDKKPEAAAAPLKIKVGVMSGP
EHQVAEIAAKVAKEKYGLDVQFVEFNDYALPNEAVSKGDLDANAMQHKPYLDEDAKAK
NLNNLVIVGNTFVYPLAGYSKKIKNVNELQEGAKVVVPNDPTNRGRALILLEKQGLIK
LKDANNLLSTVLDIVENPKKLNITEVDTSVAARALDDVDLAVVNNTYAGQVGLNAQDD
GVFVEDKDSPYVNIIVSRTDNKDSKAVQDFVKSYQTEEVYQEAQKHFKDGVVKGW"
misc_feature complement(405901..406686)
/locus_tag="CGSHiEE_02080"
/note="NMT1-like family; Region: NMT1_2; cl15260"
/db_xref="CDD:212369"
gene complement(406758..407447)
/locus_tag="CGSHiEE_02085"
/db_xref="GeneID:5225207"
CDS complement(406758..407447)
/locus_tag="CGSHiEE_02085"
/note="COG2011 ABC-type metal ion transport system,
permease component"
/codon_start=1
/transl_table=11
/product="ATP-dependent helicase HepA"
/protein_id="YP_001290269.1"
/db_xref="GI:148825516"
/db_xref="GeneID:5225207"
/translation="MFNDFLATFSQQLTPQMWGVVATATYETVYISFASTLLAVLVGV
PVGVWTFLTGKNEILQNNRTHFVLNTIINIGRSIPFIILLLILLPVTRFIVGTVLGTT
AAIIPLSICAMPFVARLTANALMEIPNGLTEAAQAMGATKWQIVRKFYLPEALPTLIN
GITLTLVTLVGYSAMAGTQGGGGLGSLAINYGVYRNMPYVTWVATIIIVLFVMISQKL
GDTLAKKVDHR"
misc_feature complement(<406938..407267)
/locus_tag="CGSHiEE_02085"
/note="Transmembrane subunit (TM) found in Periplasmic
Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
transporters which generally bind type 2 PBPs. These types
of transporters consist of a PBP, two TMs, and two
cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
cd06261"
/db_xref="CDD:119394"
misc_feature complement(order(406956..406958,406965..406970,
407010..407012,407061..407063,407070..407075,
407085..407087,407091..407096,407103..407105,
407109..407111,407115..407120,407184..407186,
407190..407195,407202..407231,407235..407246))
/locus_tag="CGSHiEE_02085"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:119394"
misc_feature complement(407184..407228)
/locus_tag="CGSHiEE_02085"
/note="conserved gate region; other site"
/db_xref="CDD:119394"
misc_feature complement(order(406989..406991,407001..407006,
407022..407060))
/locus_tag="CGSHiEE_02085"
/note="ABC-ATPase subunit interface; other site"
/db_xref="CDD:119394"
gene complement(407437..408474)
/gene="metN"
/locus_tag="CGSHiEE_02090"
/db_xref="GeneID:5225208"
CDS complement(407437..408474)
/gene="metN"
/locus_tag="CGSHiEE_02090"
/note="part of the metNIQ transport system for methionine"
/codon_start=1
/transl_table=11
/product="DL-methionine transporter ATP-binding subunit"
/protein_id="YP_001290270.1"
/db_xref="GI:148825517"
/db_xref="GeneID:5225208"
/translation="MIKLNNITKIFELPNKKLTALDNVSLNIEKGQICGVIGASGAGK
STLIRCVNLLEKPTSGSVIVDGVELTKLSDRELVLARRQIGMIFQHFNLLSSRTVFEN
VALSLELEGEPKAKIQEKITALLELVGLSEKRDAYPSNLSGGQKQRVAIARALASDPK
VLLCDEATSALDPATTQSILKLLKEINRTLGITILLITHEMEVVKQICDQVAVIDQGR
LVEQGTVGEIFANPKTELAQEFIRSTFHISLPDEYLENLTDTPKHSKAYPIIKFEFTG
RSVDAPLLSQASKKFGVELSILTSQIDYAGGVKFGYTIAEVEGDEDAITQTKVYLMEN
NVRVEVLGYVQ"
misc_feature complement(407443..408474)
/gene="metN"
/locus_tag="CGSHiEE_02090"
/note="DL-methionine transporter ATP-binding subunit;
Provisional; Region: metN; PRK11153"
/db_xref="CDD:183001"
misc_feature complement(407776..408474)
/gene="metN"
/locus_tag="CGSHiEE_02090"
/note="MetN (also known as YusC) is an ABC-type
transporter encoded by metN of the metNPQ operon in
Bacillus subtilis that is involved in methionine
transport. Other members of this system include the MetP
permease and the MetQ substrate binding protein. ABC...;
Region: ABC_MetN_methionine_transporter; cd03258"
/db_xref="CDD:73017"
misc_feature complement(408340..408363)
/gene="metN"
/locus_tag="CGSHiEE_02090"
/note="Walker A/P-loop; other site"
/db_xref="CDD:73017"
misc_feature complement(order(407878..407880,407977..407982,
408208..408210,408337..408345,408349..408354))
/gene="metN"
/locus_tag="CGSHiEE_02090"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:73017"
misc_feature complement(408208..408219)
/gene="metN"
/locus_tag="CGSHiEE_02090"
/note="Q-loop/lid; other site"
/db_xref="CDD:73017"
misc_feature complement(408025..408054)
/gene="metN"
/locus_tag="CGSHiEE_02090"
/note="ABC transporter signature motif; other site"
/db_xref="CDD:73017"
misc_feature complement(407977..407994)
/gene="metN"
/locus_tag="CGSHiEE_02090"
/note="Walker B; other site"
/db_xref="CDD:73017"
misc_feature complement(407959..407970)
/gene="metN"
/locus_tag="CGSHiEE_02090"
/note="D-loop; other site"
/db_xref="CDD:73017"
misc_feature complement(407872..407892)
/gene="metN"
/locus_tag="CGSHiEE_02090"
/note="H-loop/switch region; other site"
/db_xref="CDD:73017"
misc_feature complement(407452..407676)
/gene="metN"
/locus_tag="CGSHiEE_02090"
/note="This domain is found at the C-terminus of ABC
transporter proteins involved in D-methionine transport as
well as a number of ferredoxin-like proteins; Region: NIL;
smart00930"
/db_xref="CDD:197998"
gene 408650..409204
/locus_tag="CGSHiEE_02095"
/db_xref="GeneID:5225035"
CDS 408650..409204
/locus_tag="CGSHiEE_02095"
/note="Converts the D-glycero-beta-D-manno-heptose
1,7-bisphosphate intermediate into
D-glycero-beta-D-manno-heptose 1-phosphate"
/codon_start=1
/transl_table=11
/product="D,D-heptose 1,7-bisphosphate phosphatase"
/protein_id="YP_001290271.1"
/db_xref="GI:148825518"
/db_xref="GeneID:5225035"
/translation="MNKAIFLDRDGTLNIDYGYVHEIDNFKFIDGAIDALRELKKMGY
MLVLVTNQSGIARGYFSEEQFLQLTEWMDWSLAEQDVDLDGIYYCPHHPEGKGEYKED
CDCRKPKSGMLLQAIKELKIDPTQSIMVGDKVEDLKAGIGAKVKMNVLVRTGKPVTGE
GEGIADYVLDSIVDLPRILKRLKK"
misc_feature 408653..409180
/locus_tag="CGSHiEE_02095"
/note="D,D-heptose 1,7-bisphosphate phosphatase; Region:
GmhB_yaeD; TIGR00213"
/db_xref="CDD:129317"
misc_feature 408659..409078
/locus_tag="CGSHiEE_02095"
/note="Haloacid dehalogenase-like hydrolases. The haloacid
dehalogenase-like (HAD) superfamily includes L-2-haloacid
dehalogenase, epoxide hydrolase, phosphoserine
phosphatase, phosphomannomutase, phosphoglycolate
phosphatase, P-type ATPase, and many others; Region:
HAD_like; cd01427"
/db_xref="CDD:119389"
misc_feature order(408671..408679,408797..408802)
/locus_tag="CGSHiEE_02095"
/note="active site"
/db_xref="CDD:119389"
misc_feature 408671..408688
/locus_tag="CGSHiEE_02095"
/note="motif I; other site"
/db_xref="CDD:119389"
misc_feature 408797..408799
/locus_tag="CGSHiEE_02095"
/note="motif II; other site"
/db_xref="CDD:119389"
gene 409546..411086
/locus_tag="CGSHiEE_r09324"
/db_xref="GeneID:5225036"
rRNA 409546..411086
/locus_tag="CGSHiEE_r09324"
/product="16S ribosomal RNA"
/db_xref="GeneID:5225036"
gene 411218..411293
/locus_tag="CGSHiEE_t09372"
/db_xref="GeneID:5542137"
tRNA 411218..411293
/locus_tag="CGSHiEE_t09372"
/product="tRNA-Glu"
/db_xref="GeneID:5542137"
gene 411564..414564
/locus_tag="CGSHiEE_r09336"
/db_xref="GeneID:5542126"
rRNA 411564..414564
/locus_tag="CGSHiEE_r09336"
/product="23S ribosomal RNA"
/db_xref="GeneID:5542126"
gene 414756..414875
/locus_tag="CGSHiEE_r09312"
/db_xref="GeneID:5225037"
rRNA 414756..414875
/locus_tag="CGSHiEE_r09312"
/product="5S ribosomal RNA"
/db_xref="GeneID:5225037"
gene 415139..415726
/locus_tag="CGSHiEE_02100"
/db_xref="GeneID:5225038"
CDS 415139..415726
/locus_tag="CGSHiEE_02100"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290272.1"
/db_xref="GI:148825519"
/db_xref="GeneID:5225038"
/translation="MLKNLDEITSSIVADPQNKDFTERGIFPLFSAPKTARINIVGQA
PGLKAEQSRLYWNDKSGERLREWLGVDYDYFYNSGMFSVLPMDFYYPGKGKSGDLPPR
QGFAERWHPMILGHLPNIQLTILIGQYAQKYYLPENKDNVTNTVKNYRQFLPHFIPLV
HPSPRNQLWITKNPWFEEQVIPELQILVKQIINKD"
misc_feature 415202..415714
/locus_tag="CGSHiEE_02100"
/note="Uncharacterized subfamily of Uracil-DNA
glycosylases; Region: UDG_like_1; cd10033"
/db_xref="CDD:198431"
misc_feature order(415262..415270,415391..415393,415619..415621)
/locus_tag="CGSHiEE_02100"
/note="putative uracil binding site [chemical binding];
other site"
/db_xref="CDD:198431"
misc_feature order(415265..415270,415274..415276,415517..415525,
415616..415621,415625..415627)
/locus_tag="CGSHiEE_02100"
/note="putative active site [active]"
/db_xref="CDD:198431"
misc_feature complement(418669..421733)
/note="potential frameshift: common BLAST hit:
gi|68248825|ref|YP_247937.1| putative type I
restriction-modification system [Haemophilus]"
gene complement(422744..423898)
/locus_tag="CGSHiEE_02140"
/db_xref="GeneID:5225020"
CDS complement(422744..423898)
/locus_tag="CGSHiEE_02140"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290273.1"
/db_xref="GI:148825520"
/db_xref="GeneID:5225020"
/translation="MTKSLDKIAKQLRDSDKKVNLIYAFNGSGKTRLSKVFKNLIAPK
ENHDNEEDLTRRKILYFNAFTEDLFYWDNDLLNDTEPKLKIQPNSFIRWLIRDQGDEG
KVIGKFHHYCDEKLMPKFDIENNQITFSFARGDDTPEENIKLSKGEESNFIWSIFHTL
IEQVVAELNISEPSERTTNEFDELKYIFIDDPVSSLDENHLIQLAVDLAELVKDSPDT
IKFIITTHNPLFYNVLYNELGAKNGYILRKDENKNENERFDLEVKQGGSNKSFSYHLF
LKNLLEEVKSKDIQKYHFMLLRNLYEKTANFLGYSGWSNLLPNDDARQSYYTRIINFT
SHSTLSNEIIAEPTDAEKKIVKYLLEHLINNYGFYIEENIKEPQTDNITE"
misc_feature complement(<423755..423859)
/locus_tag="CGSHiEE_02140"
/note="AAA domain; Region: AAA_13; pfam13166"
/db_xref="CDD:205347"
misc_feature complement(422888..>423376)
/locus_tag="CGSHiEE_02140"
/note="AAA domain; Region: AAA_13; pfam13166"
/db_xref="CDD:205347"
gene complement(423900..425051)
/locus_tag="CGSHiEE_02145"
/db_xref="GeneID:5224944"
CDS complement(423900..425051)
/locus_tag="CGSHiEE_02145"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290274.1"
/db_xref="GI:148825521"
/db_xref="GeneID:5224944"
/translation="MDGSEVEWKPLDEVANIVNNARKPVKSSSRVSGNIPYYGANNIQ
DYVEGYTHEGEFVLIAEDGSASLENYSIQWAVGKFWANNHVHVVNGKEKLNNRFLYHY
LTNMNFIPFLAGKERAKLTKAKLQQIPIPIPPLSVQTEIVKILDALTALTSELTSELT
SELILRQKQYEYYREKLLSEEELGKVGFEWKTIDEISKKISSGGTPTTSNNGYYDNGT
IPWLRTQEVDFKEIWDTNIKITEDALNNSSAKWIPANCVIVAMYGATVGKTAINKIPL
TTNQACANIEINDKLACYRYIFHYLTSKYEYIKSLGSGSQTNINAQIIKKLKVPVPPI
EEQYRIVSILDKFETLTNSITEGLPLAIEQSQKRYEYYRELLLNFPSRE"
misc_feature complement(424614..425045)
/locus_tag="CGSHiEE_02145"
/note="Type I restriction modification DNA specificity
domain; Region: Methylase_S; pfam01420"
/db_xref="CDD:201785"
misc_feature complement(423915..425024)
/locus_tag="CGSHiEE_02145"
/note="Restriction endonuclease S subunits [Defense
mechanisms]; Region: HsdS; COG0732"
/db_xref="CDD:31076"
misc_feature complement(423960..424496)
/locus_tag="CGSHiEE_02145"
/note="Type I restriction modification DNA specificity
domain; Region: Methylase_S; pfam01420"
/db_xref="CDD:201785"
gene complement(425170..426714)
/locus_tag="CGSHiEE_02150"
/db_xref="GeneID:5224945"
CDS complement(425170..426714)
/locus_tag="CGSHiEE_02150"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290275.1"
/db_xref="GI:148825522"
/db_xref="GeneID:5224945"
/translation="MAAAIQQRAELQRRIWQIANDVRGSVDGWDFKQYVLGTLFYRFI
SENFANYIEAGDESVNYAQLPDEIITPDIKTDAIKTKGYFIYPSQLFKNVAANAGNNP
NLNTDLKQIFTDIENSATGFPSEQDIKGLFADFDTTSNRLGNTVKDKNDRLTAVLKGV
AELDFGKFEDNHIDLFGDAYEYLISNYAANAGKSGGEFFTPQSVSKLIAQIAMHGQTS
VNKIYDPAAGSGSLLLQAKKQFDEHIIEEGFFGQEINHTTYNLARMNMFLHNINYDKF
DIALGNTLMEPQFGDDKPFDAIVSNPPYSVKWAGSDNPTLINDERFAPAGVLAPKSKA
DFAFILHALSYLSGKGRAAIVSFPGIFYRGGAEQKIRQYLVDNNFVETVIALAPNLFY
GTSIAVNILVLSKHKPNTQTQFIDASGLFKSATNNNILEEEHIEQILKLFANKEDVPH
LAKSVSFEEIAQNDHNLAVSSYVEQKDTREVINIDELNAQIRETVTNIDRLRAEIDKI
VAEIEG"
misc_feature complement(425209..426696)
/locus_tag="CGSHiEE_02150"
/note="type I restriction system adenine methylase (hsdM);
Region: hsdM; TIGR00497"
/db_xref="CDD:211578"
misc_feature complement(426241..426684)
/locus_tag="CGSHiEE_02150"
/note="HsdM N-terminal domain; Region: HsdM_N; pfam12161"
/db_xref="CDD:204838"
misc_feature complement(<425800..426054)
/locus_tag="CGSHiEE_02150"
/note="S-adenosylmethionine-dependent methyltransferases
(SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
that use S-adenosyl-L-methionine (SAM or AdoMet) as a
substrate for methyltransfer, creating the product
S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
cd02440"
/db_xref="CDD:100107"
misc_feature complement(order(425812..425814,425863..425865,
425869..425874,425953..425958,426022..426042))
/locus_tag="CGSHiEE_02150"
/note="S-adenosylmethionine binding site [chemical
binding]; other site"
/db_xref="CDD:100107"
gene complement(426946..428985)
/locus_tag="CGSHiEE_02155"
/db_xref="GeneID:5224946"
CDS complement(426946..428985)
/locus_tag="CGSHiEE_02155"
/codon_start=1
/transl_table=11
/product="oligopeptidase A"
/protein_id="YP_001290276.1"
/db_xref="GI:148825523"
/db_xref="GeneID:5224946"
/translation="MSNPLLNIQGLPPFSQIKPEHIRPAVEKLIQDCRNTIEQVLKQP
HFTWENFILPLTETNDRLNRAWSPVSHLNSVKNSTELREAYQTCLPLLSEYSTWVGQH
KGLYNAYLALKNSAEFADYSIAQKKAIENSLRDFELSGIGLSEEKQQRYGEIVARLSE
LNSQFSNNVLDATMGWEKLIENEAELTGLPESALQAAQQSAESKGLKGYRFTLEIPSY
LPVMTYCENRALREEMYRAYATRASEQGPNAGKWDNSKVMEEILTLRVELAKLLGFNT
YTELSLATKMAEHPQQVLDFLDHLAERAKPQGEKELQELKDYCEKEFGVTELAPWDIG
FYSEKQKQHLYAINDEELRPYFPENRVISGLFELIKRIFNIRAVERKGVDTWHKDVRF
FDLIDENDQLRGSFYLDLYAREHKRGGAWMDDCIGRKRKLDGSIETPVAYLTCNFNAQ
IGNKPALFTHNEVTTLFHEFGHGIHHMLTQIDVSDVAGINGVPWDAVELPSQFMENWC
WEEEALAFISGHYETGEPLPKEKLTQLLKAKNFQAAMFILRQLEFGIFDFRLHHTFDA
EKTNQILDTLKSVKSQVAVIKGVDWARAPHSFSHIFAGGYAAGYYSYLWAEVLSADAY
SRFEEEGIFNPITGKSFLDEILTRGGSEEPMELFKRFRGREPQLDALLRHKGIMN"
misc_feature complement(426949..428985)
/locus_tag="CGSHiEE_02155"
/note="Zn-dependent oligopeptidases [Amino acid transport
and metabolism]; Region: Dcp; COG0339"
/db_xref="CDD:30687"
misc_feature complement(426955..428928)
/locus_tag="CGSHiEE_02155"
/note="Peptidase family M3 dipeptidyl carboxypeptidase
(DCP); Region: M3A_DCP; cd06456"
/db_xref="CDD:188995"
misc_feature complement(order(427147..427149,427156..427158,
427168..427176,427186..427191,427207..427212,
427336..427338,427483..427485,427492..427494,
427570..427572,427579..427584,427720..427728))
/locus_tag="CGSHiEE_02155"
/note="active site"
/db_xref="CDD:188995"
misc_feature complement(order(427492..427494,427570..427572,
427582..427584))
/locus_tag="CGSHiEE_02155"
/note="Zn binding site [ion binding]; other site"
/db_xref="CDD:188995"
gene 429110..429472
/locus_tag="CGSHiEE_02160"
/db_xref="GeneID:5224947"
CDS 429110..429472
/locus_tag="CGSHiEE_02160"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290277.1"
/db_xref="GI:148825524"
/db_xref="GeneID:5224947"
/translation="MKIIYIILGFLSLAIGIIGIFLPLLPTTPFLLLTLFFFTKGSKR
LEQWFLGTSIYQKHLKSFHENRSLKKNTKIFILTFVTTMLLIGFYFTPSVIGRSVIVA
LICIKFWFFLFWIKTENE"
misc_feature 429110..429445
/locus_tag="CGSHiEE_02160"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG2832"
/db_xref="CDD:32660"
gene 429465..431009
/locus_tag="CGSHiEE_02165"
/db_xref="GeneID:5224948"
CDS 429465..431009
/locus_tag="CGSHiEE_02165"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290278.1"
/db_xref="GI:148825525"
/db_xref="GeneID:5224948"
/translation="MNNLFALCQRSAVIFSIIFTVEACDKLDSPKPISPQIETQKNTQ
LESNRVELKRGVYSDLTLQPWQAQSEEQIQLLRDLFEGLTAYDVQGNLVPAVAENWQT
EDNKTWIFTLRENAKWSNGEPITASDFVQSWQTLSQSESPLKNYLAFMNLKNAKAVLE
KALPVESLGLFAENDRTLRIELDKASPYLPSMLAHVSLLPHYAKSTEIFISNGAYQLQ
SQAENQHILTTNPYYWAKEKVIFQQVKYQKISVDADLSDFDVVMNPKKVDQNIQDYPQ
LCTYFYEFNLSDPVLQKSAVRKAIVSMISTNNLVADIAHLHPSNIFLPKSMLGEQESV
WEPVVAEQLFSQNQISETRPLKLRIRYDDSSLNQTIAMRLNHQLSQSDLLRVENQGMS
WQELQTARTKGDFQLIRSGWCADFNDPAAFLNLFYSKSPDNKNGYKNAEFDRLFESAM
TTTSEKVRLENYAKLKGIVQQEHLVLPIFQYSTPVYLAPSIMGAQVNSVGVIYSKDLW
RKVQSQ"
misc_feature 429486..430997
/locus_tag="CGSHiEE_02165"
/note="ABC-type oligopeptide transport system, periplasmic
component [Amino acid transport and metabolism]; Region:
OppA; COG4166"
/db_xref="CDD:33908"
misc_feature 429615..430991
/locus_tag="CGSHiEE_02165"
/note="The substrate-binding component of an ABC-type
oligopetide import system contains the type 2 periplasmic
binding fold; Region: PBP2_OppA; cd08504"
/db_xref="CDD:173869"
misc_feature order(429681..429683,430248..430250,430290..430292,
430641..430643,430689..430691,430695..430709,
430905..430907)
/locus_tag="CGSHiEE_02165"
/note="peptide binding site [polypeptide binding]; other
site"
/db_xref="CDD:173869"
gene complement(431326..431976)
/gene="ribA"
/locus_tag="CGSHiEE_02170"
/db_xref="GeneID:5224934"
CDS complement(431326..431976)
/gene="ribA"
/locus_tag="CGSHiEE_02170"
/EC_number="3.5.4.25"
/note="catalyzes the conversion of GTP to formate and
2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine
and diphosphate"
/codon_start=1
/transl_table=11
/product="GTP cyclohydrolase II"
/protein_id="YP_001290279.1"
/db_xref="GI:148825526"
/db_xref="GeneID:5224934"
/translation="MAKIQLVAQANLPTEYGIFKMVGFEFLDTKKEHVALVMGDISNA
DEPVLARIHSECLTGDALHSLKCDCGFQLATALKQIQEEGRGVLIYHREEGRGIGLIN
KIRAYSLQDKGMDTIEANLALGFKADERNFEVCADMFELLGVKKVRLMTNNPEKVETM
KKAGINVVERVPLNVGENRYNTKYLDTKAKKMGHYIVHNNDEQHLMTCPHCQEEII"
misc_feature complement(431389..431970)
/gene="ribA"
/locus_tag="CGSHiEE_02170"
/note="GTP cyclohydrolase II [Coenzyme metabolism];
Region: RibA; COG0807"
/db_xref="CDD:31150"
misc_feature complement(431389..431967)
/gene="ribA"
/locus_tag="CGSHiEE_02170"
/note="GTP cyclohydrolase II (RibA). GTP cyclohydrolase
II catalyzes the conversion of GTP to
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'
phosphate, formate, pyrophosphate (APy), and GMP in the
biosynthetic pathway of riboflavin. Riboflavin is the...;
Region: GTP_cyclohydro2; cd00641"
/db_xref="CDD:88311"
misc_feature complement(order(431644..431646,431653..431658,
431662..431667,431674..431679,431701..431703,
431707..431709,431746..431748,431755..431760,
431779..431781,431785..431799,431803..431808,
431812..431814,431869..431871,431875..431877,
431881..431883,431902..431910,431914..431916,
431938..431958))
/gene="ribA"
/locus_tag="CGSHiEE_02170"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:88311"
misc_feature complement(order(431509..431511,431518..431526,
431587..431589,431593..431595,431629..431631,
431647..431649,431656..431658,431668..431670,
431689..431700,431761..431763,431770..431772,
431776..431778,431803..431805,431809..431826))
/gene="ribA"
/locus_tag="CGSHiEE_02170"
/note="active site"
/db_xref="CDD:88311"
gene 432080..432769
/locus_tag="CGSHiEE_02175"
/db_xref="GeneID:5224935"
CDS 432080..432769
/locus_tag="CGSHiEE_02175"
/codon_start=1
/transl_table=11
/product="phosphatidylglycerophosphatase B"
/protein_id="YP_001290280.1"
/db_xref="GI:148825527"
/db_xref="GeneID:5224935"
/translation="MSCTIFIWGISYQWHGNSQLTEADYWLYLLTETGSVPYALITCV
LFTLLFAFLFKNPKQWILGVIVMGISVIATQATKTGAKALFEEPRPFTVYLAEQTHST
PENFYKNDRTLRAEIAKNFYSMDAITPAWLVHHYENETGYSFPSGHTIFAATWLMLAV
GFTQLLGNRSFKAKLLVAGIAVWGLLMLISRVRLGMHYPIDLLVATLLAWLINSIIFA
FLKKKAIFVMK"
misc_feature 432113..432748
/locus_tag="CGSHiEE_02175"
/note="PAP2_like_2 proteins. PAP2 is a super-family of
phosphatases and haloperoxidases. This subgroup, which is
specific to bacteria, lacks functional characterization
and may act as a membrane-associated lipid phosphatase;
Region: PAP2_like_2; cd03392"
/db_xref="CDD:48096"
misc_feature 432212..432757
/locus_tag="CGSHiEE_02175"
/note="Membrane-associated phospholipid phosphatase [Lipid
metabolism]; Region: PgpB; COG0671"
/db_xref="CDD:31015"
misc_feature order(432323..432325,432344..432346,432515..432523,
432650..432652,432668..432670,432680..432682)
/locus_tag="CGSHiEE_02175"
/note="active site"
/db_xref="CDD:48096"
gene complement(432788..432895)
/locus_tag="CGSHiEE_02180"
/db_xref="GeneID:5224936"
CDS complement(432788..432895)
/locus_tag="CGSHiEE_02180"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290281.1"
/db_xref="GI:148825528"
/db_xref="GeneID:5224936"
/translation="MNYFIMDKTFLEQEILLPQFIIQNIERWFETHNFV"
misc_feature complement(433857..434575)
/note="potential frameshift: common BLAST hit:
gi|68248814|ref|YP_247926.1| DNA adenine methylase
[Haemophilus influenzae 86-028NP]"
misc_feature complement(434336..434717)
/note="potential frameshift: common BLAST hit:
gi|68248814|ref|YP_247926.1| DNA adenine methylase
[Haemophilus influenzae 86-028NP]"
gene complement(434719..435807)
/gene="aroB"
/locus_tag="CGSHiEE_02200"
/db_xref="GeneID:5224937"
CDS complement(434719..435807)
/gene="aroB"
/locus_tag="CGSHiEE_02200"
/EC_number="4.2.3.4"
/note="catalyzes the formation of 3-dehydroquinate from
3-deoxy-arabino-heptulonate 7-phosphate; functions in
aromatic amino acid biosynthesis"
/codon_start=1
/transl_table=11
/product="3-dehydroquinate synthase"
/protein_id="YP_001290282.1"
/db_xref="GI:148825529"
/db_xref="GeneID:5224937"
/translation="MLCVNVELQERRYPILIGSGLLQDERSYPIKRGGRVMIVTNPTV
AQFYLDTVIYALEKRGCVVDHVLLPDGEKYKTLESLNLIFTALLQGNHGRDTTIIALG
GGVIGDVAGFAAASYQRGVRLIQIPTTLLSQVDSSVGGKTAVNHELGKNMIGAFYQPS
MVIIDTLTLNTLPKREVNAGLAEVIKYGAILDYEFFEWLEQHIDELVALNPEALQHCI
SRCCQIKADVVARDETEKGDRALLNLGHTFGHAIETHLGYGNWLHGEAVSTGMMMAAA
LSEELGDISIADVSRLEKLLARANLPTVSPDTMQPEDYLPHMMRDKKVLSGKLRLVLL
KSLGQAYVANDTAHTLVLNAIRRCTQTD"
misc_feature complement(434743..435771)
/gene="aroB"
/locus_tag="CGSHiEE_02200"
/note="Dehydroquinate synthase (DHQS) catalyzes the
conversion of DAHP to DHQ in shikimate pathway for
aromatic compounds synthesis; Region: DHQS; cd08195"
/db_xref="CDD:173954"
misc_feature complement(434845..435765)
/gene="aroB"
/locus_tag="CGSHiEE_02200"
/note="Alcohol dehydrogenase, class IV [Energy production
and conversion]; Region: EutG; COG1454"
/db_xref="CDD:31643"
misc_feature complement(order(435019..435021,435058..435060,
435070..435072,435247..435249,435259..435261,
435280..435282,435304..435306,435349..435351,
435358..435360,435415..435417,435421..435426,
435475..435477,435484..435486,435493..435501,
435685..435687))
/gene="aroB"
/locus_tag="CGSHiEE_02200"
/note="active site"
/db_xref="CDD:173954"
misc_feature complement(order(435340..435357,435382..435387,
435451..435459,435463..435465,435472..435474,
435553..435558,435577..435579))
/gene="aroB"
/locus_tag="CGSHiEE_02200"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:173954"
misc_feature complement(order(435019..435021,435070..435072,
435259..435261))
/gene="aroB"
/locus_tag="CGSHiEE_02200"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:173954"
gene complement(435827..436369)
/gene="aroK"
/locus_tag="CGSHiEE_02205"
/db_xref="GeneID:5224929"
CDS complement(435827..436369)
/gene="aroK"
/locus_tag="CGSHiEE_02205"
/EC_number="2.7.1.71"
/note="catalyzes the formation of shikimate 3-phosphate
from shikimate in aromatic amino acid biosynthesis"
/codon_start=1
/transl_table=11
/product="shikimate kinase"
/protein_id="YP_001290283.1"
/db_xref="GI:148825530"
/db_xref="GeneID:5224929"
/translation="MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMDFIDSDAVIEERTG
ADISWIFDLEGEDGFRKREERIINELTQMQGIVLSTGGGAVLSKENRNYLSARGIVIY
LETTVEKQFQRTQRDKKRPLLQDAENPRQVLEDLAKIRNPLYEEIADITLPTDEQNAK
IMVNQIVDLIDNMNGLNGTL"
misc_feature complement(435854..436369)
/gene="aroK"
/locus_tag="CGSHiEE_02205"
/note="shikimate kinase; Reviewed; Region: aroK; PRK00131"
/db_xref="CDD:178887"
misc_feature complement(435890..436354)
/gene="aroK"
/locus_tag="CGSHiEE_02205"
/note="Shikimate kinase (SK) is the fifth enzyme in the
shikimate pathway, a seven-step biosynthetic pathway which
converts erythrose-4-phosphate to chorismic acid, found in
bacteria, fungi and plants. Chorismic acid is a important
intermediate in the synthesis...; Region: SK; cd00464"
/db_xref="CDD:30188"
misc_feature complement(order(435893..435895,436010..436012,
436031..436033,436313..436330))
/gene="aroK"
/locus_tag="CGSHiEE_02205"
/note="ADP binding site [chemical binding]; other site"
/db_xref="CDD:30188"
misc_feature complement(order(436262..436264,436268..436270,
436316..436318))
/gene="aroK"
/locus_tag="CGSHiEE_02205"
/note="magnesium binding site [ion binding]; other site"
/db_xref="CDD:30188"
misc_feature complement(order(435950..435952,436121..436129,
436181..436183,436190..436192,436262..436264))
/gene="aroK"
/locus_tag="CGSHiEE_02205"
/note="putative shikimate binding site; other site"
/db_xref="CDD:30188"
gene complement(436656..438467)
/locus_tag="CGSHiEE_02210"
/db_xref="GeneID:5224930"
CDS complement(436656..438467)
/locus_tag="CGSHiEE_02210"
/codon_start=1
/transl_table=11
/product="NAD nucleotidase"
/protein_id="YP_001290284.1"
/db_xref="GI:148825531"
/db_xref="GeneID:5224930"
/translation="MLLSKKSATFALSAFAMLFTSVALAKEAPQAHKAVELSILHIND
HHSYLEPHETRINLNGQQTKVDIGGFSAVNAKLNKLRKKYKNPLVLHAGDAITGTLYF
TLFGGSADAAVMNAGNFHYFTLGNHEFDAGNEGLLKLLEPLKIPVLSANVIPDKSSIL
YNKWKPYDIFTVDGEKIAIIGLDTVNKTVNSSSPGKDVKFYDEIATAQIMANALKQQG
INKIILLSHAGSEKNIEIAQKVNDIDVIVTGDSHYLYGNDELRSLKLPVIYEYPLEFK
NPNGEPVFVMEGWAYSAVVGDLGVKFSPEGIASITRKIPHVLMSSHKLQVKNSEGKWA
ELTGDERKKALDTLKSMKSISLDDHDAKTDKLIAKYKSEKDRLAQEIVGVITGSAMPG
GSANRIPNKAGSNPEGSIATRFIAETMYNELKTVDLTIQNAGGVRADILPGNVTFNDA
YTFLPFGNTLYTYKMEGSLVKQVLEDAMQFALVDGSTGAFPYGAGIRYEANETPNAEG
KRLVSVEVLNKQTQQWEPIDDNKRYLVGTNAYVAGGKDGYKTFGKLFNDPKYEGVDTY
LPDAESFIKFMKKHPHFEAYTSSNVKFNASTDALPKK"
misc_feature complement(436725..438359)
/locus_tag="CGSHiEE_02210"
/note="NAD pyrophosphatase/5'-nucleotidase NadN; Region:
nadN; TIGR01530"
/db_xref="CDD:211667"
misc_feature complement(437514..438359)
/locus_tag="CGSHiEE_02210"
/note="CD73 ecto-5'-nucleotidase and related proteins,
N-terminal metallophosphatase domain; Region: MPP_CD73_N;
cd07409"
/db_xref="CDD:163652"
misc_feature complement(order(437712..437714,437718..437720,
437787..437789,437898..437900,438078..438080,
438087..438092,438186..438188,438330..438332,
438336..438338))
/locus_tag="CGSHiEE_02210"
/note="active site"
/db_xref="CDD:163652"
misc_feature complement(order(437712..437714,437718..437720,
437787..437789,438090..438092,438186..438188,
438330..438332,438336..438338))
/locus_tag="CGSHiEE_02210"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:163652"
misc_feature complement(436824..437288)
/locus_tag="CGSHiEE_02210"
/note="5'-nucleotidase, C-terminal domain; Region:
5_nucleotid_C; pfam02872"
/db_xref="CDD:202440"
gene 439557..439805
/gene="rpsP"
/locus_tag="CGSHiEE_02225"
/db_xref="GeneID:5224931"
CDS 439557..439805
/gene="rpsP"
/locus_tag="CGSHiEE_02225"
/note="binds to lower part of 30S body where it stabilizes
two domains; required for efficient assembly of 30S; in
Escherichia coli this protein has nuclease activity"
/codon_start=1
/transl_table=11
/product="30S ribosomal protein S16"
/protein_id="YP_001290285.1"
/db_xref="GI:148825532"
/db_xref="GeneID:5224931"
/translation="MVTIRLSRGGAKKRPFYQIVVADSRSPRDGRFIERVGFFNPIAQ
GNAERLRINLERVNHWVAQGASLSDRVASLVKEAQKAA"
misc_feature 439557..439781
/gene="rpsP"
/locus_tag="CGSHiEE_02225"
/note="30S ribosomal protein S16; Reviewed; Region: rpsP;
PRK00040"
/db_xref="CDD:178814"
gene 439851..440378
/gene="rimM"
/locus_tag="CGSHiEE_02230"
/db_xref="GeneID:5224932"
CDS 439851..440378
/gene="rimM"
/locus_tag="CGSHiEE_02230"
/note="Essential for efficient processing of 16S rRNA"
/codon_start=1
/transl_table=11
/product="16S rRNA-processing protein RimM"
/protein_id="YP_001290286.1"
/db_xref="GI:148825533"
/db_xref="GeneID:5224932"
/translation="MEQQHIEVVGKLGSTYGIRGWLRIYSSTEQAESIFDYQPWFLKI
KGEWQSIELENWRYHNHEIIVKLKGVDDREAAQILANVEIGVDLSVFPELEEGDYYWH
DLIGCTVVNLEGYTMGTVTEMMETGSNDVLVVKANTKDAFGKQERLIPFLYEQVVKRV
DLTTKTIEVDWDAGF"
misc_feature 439872..440375
/gene="rimM"
/locus_tag="CGSHiEE_02230"
/note="16S rRNA-processing protein RimM; Provisional;
Region: rimM; PRK00122"
/db_xref="CDD:178881"
misc_feature 439872..440111
/gene="rimM"
/locus_tag="CGSHiEE_02230"
/note="RimM N-terminal domain; Region: RimM; pfam01782"
/db_xref="CDD:201971"
gene 440416..441156
/gene="trmD"
/locus_tag="CGSHiEE_02235"
/db_xref="GeneID:5224933"
CDS 440416..441156
/gene="trmD"
/locus_tag="CGSHiEE_02235"
/note="methylates guanosine-37 in various tRNAs; uses
S-adenosyl-L-methionine to transfer methyl group to tRNA"
/codon_start=1
/transl_table=11
/product="tRNA (guanine-N(1)-)-methyltransferase"
/protein_id="YP_001290287.1"
/db_xref="GI:148825534"
/db_xref="GeneID:5224933"
/translation="MWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRNFTFD
KHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTEL
AQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVL
GKQASAEEDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWL
RRPELLEGLALTDEQRKLLKEAQAEHNS"
misc_feature 440416..441147
/gene="trmD"
/locus_tag="CGSHiEE_02235"
/note="tRNA (guanine-N(1)-)-methyltransferase; Reviewed;
Region: trmD; PRK00026"
/db_xref="CDD:178803"
gene 441193..441543
/gene="rplS"
/locus_tag="CGSHiEE_02240"
/db_xref="GeneID:5224824"
CDS 441193..441543
/gene="rplS"
/locus_tag="CGSHiEE_02240"
/note="this protein is located at the 30S-50S ribosomal
subunit interface and may play a role in the structure and
function of the aminoacyl-tRNA binding site"
/codon_start=1
/transl_table=11
/product="50S ribosomal protein L19"
/protein_id="YP_001290288.1"
/db_xref="GI:148825535"
/db_xref="GeneID:5224824"
/translation="MSNIIKQLEQEQLKQNVPSFRPGDTLEVKVWVVEGSKRRLQAFE
GVVIAIRNRGLHSAFTLRKVSNGVGVERVFQTHSPAVDSIAVKRKGAVRKAKLYYLRE
RSGKSARIKERLGA"
misc_feature 441196..441540
/gene="rplS"
/locus_tag="CGSHiEE_02240"
/note="50S ribosomal protein L19; Provisional; Region:
rplS; PRK05338"
/db_xref="CDD:180025"
misc_feature complement(441652..442624)
/note="potential frameshift: common BLAST hit:
gi|68248805|ref|YP_247917.1| selenide, water dikinase
[Haemophilus influenzae 86-028NP]"
gene complement(442751..443608)
/locus_tag="CGSHiEE_02255"
/db_xref="GeneID:5224825"
CDS complement(442751..443608)
/locus_tag="CGSHiEE_02255"
/note="Transfers myristate or laurate, activated on ACP,
to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA"
/codon_start=1
/transl_table=11
/product="lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA
acyltransferase"
/protein_id="YP_001290289.1"
/db_xref="GI:148825536"
/db_xref="GeneID:5224825"
/translation="MVIFFLLLLAFVPFRLRDKFAGKLGIWIGHKAKKQRTRAQTNLQ
YCFPHWTEQQREQVIDKMFTVVTQVMFGIGEIAIRSKKHLQKRSEFIGLEHIEQAKAE
GKNIILMVPHGWAIDASGIILHTQGMPMTSMYNPHRNPLVDWLWTIARQRFGGKMHAR
QNGIKPFLNHVRKGEMGYYLPDEDFGAEQSVFVDFFGTYKATLPGLNKMAKLSKAVVI
PMFPRYNAETGKYEMEIHPAMNLSDDPEQSARAMNEEIESFVTPSPEQYVWILQLLRT
RKDGEDLYN"
misc_feature complement(442781..443605)
/locus_tag="CGSHiEE_02255"
/note="Bacterial lipid A biosynthesis acyltransferase;
Region: Lip_A_acyltrans; pfam03279"
/db_xref="CDD:112109"
misc_feature complement(442799..443356)
/locus_tag="CGSHiEE_02255"
/note="Lysophospholipid Acyltransferases (LPLATs) of
Glycerophospholipid Biosynthesis: LABLAT-like; Region:
LPLAT_LABLAT-like; cd07984"
/db_xref="CDD:153246"
misc_feature complement(order(443054..443062,443198..443209,
443258..443260,443264..443266,443273..443275))
/locus_tag="CGSHiEE_02255"
/note="putative acyl-acceptor binding pocket; other site"
/db_xref="CDD:153246"
gene complement(443755..444522)
/locus_tag="CGSHiEE_02260"
/db_xref="GeneID:5224826"
CDS complement(443755..444522)
/locus_tag="CGSHiEE_02260"
/note="COG0730 Predicted permeases"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_001290290.1"
/db_xref="GI:148825537"
/db_xref="GeneID:5224826"
/translation="MDIGIDLLAILFCVGFVASFIDAIAGGGGLITIPALLMTGMPPA
MALGTNKLQAMGGALSASLYFLRKRAVNLRDIWFILIWVFLGSALGTLLIQSIDMAIF
KKILPFLILAIGLYFLFTPKLGDKDRKQRLSYMLFGLLVSPFLGFYDGFFGPGTGSIM
SLACVTLLGFNLPKATAHAKVMNFTSNLASFALFLLGGQILWKVGFVMMAGSILGANL
GAKMVMTKGKTLIRPMVVIMSFMMTAKMVYDQGWFHF"
misc_feature complement(443773..444516)
/locus_tag="CGSHiEE_02260"
/note="Predicted permeases [General function prediction
only]; Region: COG0730; cl00498"
/db_xref="CDD:186038"
misc_feature complement(443785..444492)
/locus_tag="CGSHiEE_02260"
/note="Sulfite exporter TauE/SafE; Region: TauE;
pfam01925"
/db_xref="CDD:202049"
gene complement(444540..445400)
/gene="mepA"
/locus_tag="CGSHiEE_02265"
/db_xref="GeneID:5224827"
CDS complement(444540..445400)
/gene="mepA"
/locus_tag="CGSHiEE_02265"
/note="D-alanyl-D-alanine endopeptidase; functions in
hydrolyzing cell wall peptidoglycan; similar to LAS
metallopeptidases; forms a dimer in periplasm"
/codon_start=1
/transl_table=11
/product="penicillin-insensitive murein endopeptidase"
/protein_id="YP_001290291.1"
/db_xref="GI:148825538"
/db_xref="GeneID:5224827"
/translation="MNKILLKTTIIFTALFSLNVVASPLDWQKVKRPIPSEDGKASPI
GSYTNGCIIGAQALPPKGEGYQVIRMNRNRYYGHPNMIQYLERLGQRIKAAGLPTMLV
GDIAMPGGGRFLTGHASHQMGLDADIWLRMGEMSDADALNSDGKGLLVVDRKAQRVDE
RVWNSNHATLIKLAAQDPNVTRIFVNPAIKVKLCQTAGNDRGWLHKVRPWYGHNSHFH
VRLTCPADAPYCENQAPVPAGDGCGDELYSWFEPPKPGASVSKPKVTPSEPFLCQQIL
NSPNRSEWLE"
misc_feature complement(444543..445394)
/gene="mepA"
/locus_tag="CGSHiEE_02265"
/note="Murein endopeptidase [Cell envelope biogenesis,
outer membrane]; Region: MepA; COG3770"
/db_xref="CDD:33565"
misc_feature complement(444564..445385)
/gene="mepA"
/locus_tag="CGSHiEE_02265"
/note="penicillin-insensitive murein endopeptidase;
Reviewed; Region: mepA; PRK09429"
/db_xref="CDD:181849"
gene complement(445572..446645)
/locus_tag="CGSHiEE_02270"
/db_xref="GeneID:5224828"
CDS complement(445572..446645)
/locus_tag="CGSHiEE_02270"
/EC_number="4.2.3.5"
/note="catalyzes the formation of chorismate from
5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino
acid biosynthesis"
/codon_start=1
/transl_table=11
/product="chorismate synthase"
/protein_id="YP_001290292.1"
/db_xref="GI:148825539"
/db_xref="GeneID:5224828"
/translation="MAGNTIGQLFRVTTFGESHGIALGCIVDGVPPNLELSEKDIQPD
LDRRKPGTSRYTTPRREDDEVQILSGVFEGKTTGTSIGMIIKNGDQRSQDYGDIKDRF
RPGHADFTYQQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLREHFGIEVRGFLSQI
GNIKIAPQKVGQIDWEKVNSNPFFCPDESAVEKFDELIRELKKEGDSIGAKLTVIAEN
VPVGLGEPVFDRLDADLAHALMGINAVKGVEIGDGFAVVKQRGSEHRDEMTPNGFESN
HAGGILGGISSGQPIIATIALKPTSSITIPGRSINLNGKPVEVVTKGRHDPCVGIRAV
PIAEAMVAIVLLDHLLRFKAQCK"
misc_feature complement(445602..446618)
/locus_tag="CGSHiEE_02270"
/note="Chorismase synthase, the enzyme catalyzing the
final step of the shikimate pathway; Region:
Chorismate_synthase; cd07304"
/db_xref="CDD:143612"
misc_feature complement(order(445626..445628,445740..445742,
445749..445760,445764..445766,445785..445793,
445797..445805,445812..445814,445860..445865,
445875..445880,445884..445889,445896..445910,
445917..445919,445923..445928,445932..445940,
445947..445952,445956..445958,445968..445976,
445980..445982,446013..446030,446043..446045,
446244..446246,446268..446273,446301..446315,
446394..446396,446400..446402,446406..446408,
446412..446417,446436..446441,446445..446450,
446547..446552,446562..446564,446568..446570,
446574..446576,446595..446615))
/locus_tag="CGSHiEE_02270"
/note="Tetramer interface [polypeptide binding]; other
site"
/db_xref="CDD:143612"
misc_feature complement(order(445647..445649,445659..445661,
445740..445748,445752..445757,445914..445919,
446250..446252,446259..446270,446328..446333,
446502..446504,446589..446591))
/locus_tag="CGSHiEE_02270"
/note="active site"
/db_xref="CDD:143612"
misc_feature complement(order(445650..445652,445659..445661,
445668..445670,445740..445748,445752..445754,
445914..445922,446265..446267,446271..446273,
446325..446333))
/locus_tag="CGSHiEE_02270"
/note="FMN-binding site [chemical binding]; other site"
/db_xref="CDD:143612"
gene complement(446655..449975)
/locus_tag="CGSHiEE_02275"
/db_xref="GeneID:5224809"
CDS complement(446655..449975)
/locus_tag="CGSHiEE_02275"
/note="small mechanosensitive ion channel (MscS) that
opens in response to stretch forces in the membrane lipid
bilayer; maintains cell turgor through accumulation and
release of potassium; large protein class of MscS"
/codon_start=1
/transl_table=11
/product="potassium efflux protein KefA"
/protein_id="YP_001290293.1"
/db_xref="GI:148825540"
/db_xref="GeneID:5224809"
/translation="MKIPPFFTALFASAMFTLSVSQGVLAANSTNVLPTEQSLKADLA
NAQKMSEGEAKNRLLAELQTSIDLLQQIQAQQKINDALQTTLSHSESEIRKNNAEIQA
LKKQQETATSTDDNAQSQDYLQNSLTKLNDQLQDTQNALSTANAQLAGQSSISERAQA
ALTENVVRTQQINQQLANNDIGSILRKQYQIELQLIDLKNSYNQNLLKNNDQLSLLYQ
SRYDLLNLRLQVQQQNIIAIQEVINQKNLQQSQNQVEQAQQQQKTVQNDYIQKELDRN
AQLGQYLLQQTEKANSLTQDELRMRNILDSLTQTQRTIDEQISALQGTLVLSRIIQQQ
KQKLPTNLNIQGLSKQIADLRVHIFDITQKRNELYDLDNYINKVESEDGKQFTEAERT
QVKTLLTERRKMTSDLIKSLNNQLNLAISLELTQLQITQISDQIQSKLEQQSFWVKSN
NPINLDWVKMLPRALIEQFNGMLKKLGFPTNYDNLPYLLMYFLGLFIVGGAIFKFKNR
IKQQLNKINREIHRLDTDSQWSTPLALLLTAFLTLSSTLWFLAVCQMIGFFFFKNPEE
FWHWSFSMAGYWWFFTFWISLFRPNGIFVNHFESSKENAQRFRGVIQRIIIVVVLLLN
TSVFSNVTDAGLANDVLGQINTIAALIFCAAIIAPRFNRVLRSYEPETNKHHWLIRIV
QIGLRLIPVGLIVLIVLGYYYTALNLIEHFIHSYIAWCVWWLVRNTIYRGITVSSRRL
AHRRLAEKRRQKALENNYENISSDDVVAVGEPEESLALNDVRSQLLRFVDLFIWTALL
GIFYYVWSDLVTVVSYLREITLWQQTTTTDAGTVMESITLFNLLVALVIVGITYVLVR
NISGILEVLIFSRVNLSQGTPYTITTLLTYIFIAIGGAWAFATLGMSWSKLQWLFAAL
SVGLGFGMQEIFANFVSGIILLFERPIRVGDVVTINEVSGTVAKIRIRAITLIDFDRK
EVIVPNKSFVTGQVTNWALSNTMTRLVISVGVAYGSDLTLVRQLLLQAADEQPTILRD
PKPSAYFLTFGASTLDHELRVYVEQVGDRTSTTDALNRRINELFAEHNIDIAFNQLDV
FIKNNDTGEEIPFVDVKK"
misc_feature complement(446658..449975)
/locus_tag="CGSHiEE_02275"
/note="hypothetical protein; Provisional; Region:
PRK11281"
/db_xref="CDD:183073"
misc_feature complement(447513..448511)
/locus_tag="CGSHiEE_02275"
/note="Mechanosensitive ion channel inner membrane domain
1; Region: MscS_TM; pfam12794"
/db_xref="CDD:205075"
misc_feature complement(446733..447281)
/locus_tag="CGSHiEE_02275"
/note="Mechanosensitive ion channel; Region: MS_channel;
pfam00924"
/db_xref="CDD:201506"
gene complement(450017..451375)
/locus_tag="CGSHiEE_02280"
/db_xref="GeneID:5224810"
CDS complement(450017..451375)
/locus_tag="CGSHiEE_02280"
/EC_number="6.2.1.26"
/note="COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid
ligases II"
/codon_start=1
/transl_table=11
/product="O-succinylbenzoic acid--CoA ligase"
/protein_id="YP_001290294.1"
/db_xref="GI:148825541"
/db_xref="GeneID:5224810"
/translation="MYPWQDFAIQPDFSDKIALRTTQGDVLTWIELTTKINQTVAFLQ
KKDVNAESAVAFVGKNSEKILFLYLATIQLGAKVLGINPAFPQEKIAKLCEFYQIDFC
FYDKDLLNLQEIGVFTQKADFFRPATMTLTSGSTGLPKAVVHNVQAHLDNAKGVCNLM
KFDCNQSWLLSLPLYHVSGQGIVWRWLYCGAQLHFPEDDFYASLLKTTHVSLVPTQLQ
RLLDYLQENPSISFATRHILLGGTHIPTELTQNMVKYGIETYSGYGMTEMASTVFAKK
SDRKQGVGQPLLGREYCLVNDEIWLKGAGLAMGYWKDRQIVPLTNNQGWIQTKDKGIW
QEGELVIIGRLDNMFISGGENIQPEEIEQVIIQHSSVNQVFVLPQKNKEFGQRPVALV
DFNEPFSKSAVENLMFFLQDKLARFKQPIAYYPLPLMLEKGIKISRKQLANWLAKQDE
IN"
misc_feature complement(450020..451375)
/locus_tag="CGSHiEE_02280"
/note="O-succinylbenzoic acid--CoA ligase; Provisional;
Region: PRK09029"
/db_xref="CDD:181616"
misc_feature complement(450248..451294)
/locus_tag="CGSHiEE_02280"
/note="AMP-binding enzyme; Region: AMP-binding; pfam00501"
/db_xref="CDD:201270"
misc_feature complement(451378..451972)
/note="potential frameshift: common BLAST hit:
gi|68248798|ref|YP_247910.1| SeqA [Haemophilus influenzae
86-028NP]"
gene 452043..452825
/locus_tag="CGSHiEE_02295"
/db_xref="GeneID:5224811"
CDS 452043..452825
/locus_tag="CGSHiEE_02295"
/note="COG0596 Predicted hydrolases or acyltransferases
(alpha/beta hydrolase superfamily)"
/codon_start=1
/transl_table=11
/product="esterase/lipase"
/protein_id="YP_001290295.1"
/db_xref="GI:148825542"
/db_xref="GeneID:5224811"
/translation="MAKSLLNYQFHQVKQTINTPVLIFIHGLFGDMDNLGVIARAFSE
HYSILRIDLRNHGHSFHSEKMNYQLMAEDVIAVIRHLNLSKVILIGHSMGGKTAMKIT
ALCPELVEKLIVIDMSPMPYEGFGHKDVFNGLFAVKNAKPENRQQAKPILKQEINDED
VVQFMLKSFDVNSADCFRFNLTALFNNYANIMDWEKVRVFTPTLFIKGGNSSYIKIEN
SEKILEQFPNATAFTINGSGHWVHAEKPDFVIRAIKRFLNKN"
misc_feature 452058..452822
/locus_tag="CGSHiEE_02295"
/note="acyl-CoA esterase; Provisional; Region: PRK10673"
/db_xref="CDD:182637"
misc_feature 452100..>452501
/locus_tag="CGSHiEE_02295"
/note="Esterases and lipases (includes fungal lipases,
cholinesterases, etc.) These enzymes act on carboxylic
esters (EC: 3.1.1.-). The catalytic apparatus involves
three residues (catalytic triad): a serine, a glutamate or
aspartate and a histidine.These...; Region:
Esterase_lipase; cl12031"
/db_xref="CDD:211462"
gene 452922..453446
/locus_tag="CGSHiEE_02300"
/db_xref="GeneID:5224812"
CDS 452922..453446
/locus_tag="CGSHiEE_02300"
/note="An electron-transfer protein; flavodoxin binds one
FMN molecule, which serves as a redox-active prosthetic
group"
/codon_start=1
/transl_table=11
/product="flavodoxin FldA"
/protein_id="YP_001290296.1"
/db_xref="GI:148825543"
/db_xref="GeneID:5224812"
/translation="MAIVGLFYGSDTGNTENIAKQIQKQLGSDLIDIRDIAKSSKEDI
EAYDFLLFGIPTWYYGEAQADWDDFFPTLEEIDFTDKLVGIFGCGDQEDYADYFCDAI
GTVRDIIEPHGAIVVGNWPTEGYNFEASKALLEDGTFIGLCIDEDRQPELTAERVEKW
CKQIYDEMCLAELA"
misc_feature 452922..453431
/locus_tag="CGSHiEE_02300"
/note="flavodoxin FldA; Validated; Region: PRK09267"
/db_xref="CDD:181740"
gene 453475..453915
/locus_tag="CGSHiEE_02305"
/db_xref="GeneID:5224813"
CDS 453475..453915
/locus_tag="CGSHiEE_02305"
/note="COG0735 Fe2+/Zn2+ uptake regulation proteins"
/codon_start=1
/transl_table=11
/product="ferric uptake regulation protein"
/protein_id="YP_001290297.1"
/db_xref="GI:148825544"
/db_xref="GeneID:5224813"
/translation="MSEENIKLLKKVGLKITEPRLTILALMQNHKNEHFSAEEVYKIL
LEQGSEIGLATVYRVLNQFDEAHIVIRHNFEGNKSVFELAPTEHHDHIICEDCGKVFE
FTDNIIEQRQREISEKYGIKLKTHNVYLYGKCSDINHCDENNSK"
misc_feature 453475..453912
/locus_tag="CGSHiEE_02305"
/note="ferric uptake regulator; Provisional; Region: fur;
PRK09462"
/db_xref="CDD:181877"
misc_feature 453529..453876
/locus_tag="CGSHiEE_02305"
/note="Ferric uptake regulator(Fur) and related
metalloregulatory proteins; typically iron-dependent,
DNA-binding repressors and activators; Region: Fur_like;
cd07153"
/db_xref="CDD:133478"
misc_feature order(453574..453576,453718..453720,453739..453741,
453745..453747,453778..453780)
/locus_tag="CGSHiEE_02305"
/note="metal binding site 2 [ion binding]; metal-binding
site"
/db_xref="CDD:133478"
misc_feature 453628..453672
/locus_tag="CGSHiEE_02305"
/note="putative DNA binding helix; other site"
/db_xref="CDD:133478"
misc_feature order(453736..453738,453742..453744,453799..453801,
453850..453852)
/locus_tag="CGSHiEE_02305"
/note="metal binding site 1 [ion binding]; metal-binding
site"
/db_xref="CDD:133478"
misc_feature order(453751..453759,453805..453810,453835..453843,
453847..453873)
/locus_tag="CGSHiEE_02305"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:133478"
misc_feature order(453754..453756,453763..453765,453874..453876)
/locus_tag="CGSHiEE_02305"
/note="structural Zn2+ binding site [ion binding]; other
site"
/db_xref="CDD:133478"
gene complement(454023..455372)
/locus_tag="CGSHiEE_02310"
/db_xref="GeneID:5224784"
CDS complement(454023..455372)
/locus_tag="CGSHiEE_02310"
/EC_number="1.4.1.4"
/note="converts 2-oxoglutarate to glutamate; in
Escherichia coli this enzyme plays a role in glutamate
synthesis when the cell is under energy restriction; uses
NADPH; forms a homohexamer"
/codon_start=1
/transl_table=11
/product="glutamate dehydrogenase"
/protein_id="YP_001290298.1"
/db_xref="GI:148825545"
/db_xref="GeneID:5224784"
/translation="MSKVASLDAFLTKVAQRDGYQPEFLQAVREVFTSIWPFLEANPK
YRSEALLERLVEPERAFQFRVAWTDDKGKVQVNRAFRVQFNSAIGPFKGGMRFHPSVN
LSILKFLGFEQIFKNALTTLPMGGAKGGSDFDPKGKSDAEVMRFCQALMTELYRHVGA
DTDVPAGDIGVGGREVGYLAGYMKKLSNQSACVFTGRGLSFGGSLIRPEATGYGLIYF
AQAMLAEKGDSFAGKVVSVSGSGNVAQYAIEKALSLGAKVVTCSDSSGYVYDPNGFTT
EKLATLFDIKNTKRGRVKDYAEQFGLQYFEGKRPWEVQVDIALPCATQNELELSDAQR
LIKNGVKLVAEGANMPTTIEATEALLAADVLFGPGKAANAGGVATSGLEMAQSSQRLY
WTAEEVDAQLHRIMLDIHANCKKYGTIEGQENINYVVGANVAGFVKVADAMLAQGVY"
misc_feature complement(454026..455372)
/locus_tag="CGSHiEE_02310"
/note="glutamate dehydrogenase; Provisional; Region:
PRK09414"
/db_xref="CDD:181834"
misc_feature complement(454830..455204)
/locus_tag="CGSHiEE_02310"
/note="Glu/Leu/Phe/Val dehydrogenase, dimerisation domain;
Region: ELFV_dehydrog_N; pfam02812"
/db_xref="CDD:202408"
misc_feature complement(454029..454790)
/locus_tag="CGSHiEE_02310"
/note="NAD(P) binding domain of glutamate dehydrogenase,
subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313"
/db_xref="CDD:133455"
misc_feature complement(order(454329..454337,454404..454409,
454581..454586,454644..454652))
/locus_tag="CGSHiEE_02310"
/note="NAD(P) binding site [chemical binding]; other site"
/db_xref="CDD:133455"
gene complement 