LOCUS NC_014154 45943 bp DNA circular BCT 29-APR-2011
DEFINITION Thiomonas intermedia K12 plasmid pTINT01, complete sequence.
ACCESSION NC_014154
VERSION NC_014154.1 GI:296137611
DBLINK Project: 48825
BioProject: PRJNA48825
KEYWORDS .
SOURCE Thiomonas intermedia K12
ORGANISM Thiomonas intermedia K12
Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
Thiomonas.
REFERENCE 1 (bases 1 to 45943)
AUTHORS Lucas,S., Copeland,A., Lapidus,A., Cheng,J.-F., Bruce,D.,
Goodwin,L., Pitluck,S., Davenport,K., Detter,J.C., Han,C.,
Tapia,R., Land,M., Hauser,L., Kyrpides,N., Ovchinnikova,G.,
Kerfeld,C.A., Cannon,G.C., Heinhorst,S. and Woyke,T.
CONSRTM US DOE Joint Genome Institute
TITLE Complete sequence of plasmid1 of Thiomonas intermedia K12
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 45943)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (14-MAY-2010) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 45943)
AUTHORS Lucas,S., Copeland,A., Lapidus,A., Cheng,J.-F., Bruce,D.,
Goodwin,L., Pitluck,S., Davenport,K., Detter,J.C., Han,C.,
Tapia,R., Land,M., Hauser,L., Kyrpides,N., Ovchinnikova,G.,
Kerfeld,C.A., Cannon,G.C., Heinhorst,S. and Woyke,T.
CONSRTM US DOE Joint Genome Institute
TITLE Direct Submission
JOURNAL Submitted (28-APR-2010) US DOE Joint Genome Institute, 2800
Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to CP002022.
URL -- http://www.jgi.doe.gov
JGI Project ID: 4083905
Source DNA and organism available from Sabine Heinhorst
(sabine.heinhorst@usm.edu)
Contacts: Sabine Heinhorst (sabine.heinhorst@usm.edu)
Tanja Woyke (microbe@cuba.jgi-psf.org)
Annotation done by JGI-ORNL and JGI-PGF
Finishing done by JGI-LANL
There is a structural polymorphism that occurs with this organism.
There is significant data from transposon bombs and pcr indicating
that the two plasmids are joined into one plasmid in some part of
the population and possibly even into the main chromosome in some
part of the population. It was most reasonable to finish the genome
with two plasmids due to a 9.3 kb repeat that is in both plasmids.
There is one copy of the 9.3 kb repeat in the smallest plasmid
(plasmid2). The error rate for the smallest plasmid is artificially
high (1.87/10kb); there is no low quality and all of the sequence
is supported by the Solexa data.
Finished microbial genomes have been curated to close all gaps with
greater than 98% coverage of at least two independent clones. Each
base pair has a minimum q (quality) value of 30 and the total error
rate is less than one per 50000.
The JGI and collaborators endorse the principles for the
distribution and use of large scale sequencing data adopted by the
larger genome sequencing community and urge users of this data to
follow them. it is our intention to publish the work of this
project in a timely fashion and we welcome collaborative
interaction on the project and analysis.
(http://www.genome.gov/page.cfm?pageID=10506376).
##Metadata-START##
Organism Display Name :: Thiomonas intermedia K12
GOLD Stamp ID :: Gi02106
Greengenes ID :: 104125
Funding Program :: DOE-CSP 2008
Isolation Site :: sewage pipe in Hamburg Germany
Isolation Country :: Germany
Latitude :: 53.553407
Longitude :: 9.992196
Oxygen Requirement :: Aerobe
Cell Shape :: Rod-shaped
Motility :: Motile
Sporulation :: Nonsporulating
Temperature Range :: Mesophile
Gram Staining :: gram-
Biotic Relationship :: Free living
Diseases :: None
Phenotypes :: Acidophile
Energy Source :: Mixotroph
##Metadata-END##
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..45943
/organism="Thiomonas intermedia K12"
/mol_type="genomic DNA"
/strain="K12"
/isolation_source="sewage pipe"
/db_xref="taxon:75379"
/plasmid="pTINT01"
/country="Germany: Hamburg"
/lat_lon="53.553407 N 9.992196 E"
gene 166..621
/locus_tag="Tint_3199"
/db_xref="GeneID:9154029"
CDS 166..621
/locus_tag="Tint_3199"
/inference="protein motif:TFAM:TIGR02051"
/note="TIGRFAM: Hg(II)-responsive transcriptional
regulator;
PFAM: Transcription regulator MerR DNA binding; regulatory
protein MerR;
KEGG: net:Neut_2571 putative transcriptional regulator
MerR;
SMART: regulatory protein MerR"
/codon_start=1
/transl_table=11
/product="MerR family transcriptional regulator"
/protein_id="YP_003644853.1"
/db_xref="GI:296137612"
/db_xref="InterPro:IPR000551"
/db_xref="InterPro:IPR009061"
/db_xref="InterPro:IPR011794"
/db_xref="InterPro:IPR015358"
/db_xref="GeneID:9154029"
/translation="MENNLENLTIGVFAKAAGVNVETIRFYQRRGLLPEPDKPYGSIR
RYGEVDVTRVRFVKSAQRLGFSLDEIAELLRLEDGTHCEEASSLAEHKLQDVREKMAD
LARMEAVLSGLVCACHARKGNVSCPLIASLQDGTNLTVSVRGDHGLTTP"
misc_feature 166..591
/locus_tag="Tint_3199"
/note="putative transcriptional regulator MerR;
Provisional; Region: PRK13752"
/db_xref="CDD:184302"
misc_feature 187..564
/locus_tag="Tint_3199"
/note="Helix-Turn-Helix DNA binding domain of the MerR1
transcription regulator; Region: HTH_MerR1; cd04783"
/db_xref="CDD:133410"
misc_feature order(190..198,238..240,289..297)
/locus_tag="Tint_3199"
/note="DNA binding residues [nucleotide binding]"
/db_xref="CDD:133410"
misc_feature order(331..333,340..342,352..357,382..384,409..414,
421..423,430..432,442..444,460..462,472..474,481..486,
505..507,520..525,541..543,547..549)
/locus_tag="Tint_3199"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:133410"
misc_feature order(409..411,514..516,541..543)
/locus_tag="Tint_3199"
/note="mercury binding site [ion binding]; other site"
/db_xref="CDD:133410"
gene 749..1639
/locus_tag="Tint_3200"
/db_xref="GeneID:9153983"
CDS 749..1639
/locus_tag="Tint_3200"
/inference="similar to AA sequence:KEGG:Pnap_4981"
/note="KEGG: pna:Pnap_4981 mucin-associated surface
protein"
/codon_start=1
/transl_table=11
/product="mucin-associated surface protein"
/protein_id="YP_003644854.1"
/db_xref="GI:296137613"
/db_xref="GeneID:9153983"
/translation="MGREATITPEQVHAVADAIKAEGSKPTLRAVRERLGQGSMGTIA
KLLQQWKVGQERQAAAELVLPPALQRAVLDFMAAELSATRAPLEAELAEQQQTAADLA
AENERQADTITEQGEALDALAAEKAAAEGKAGQLAADLIGAKEEAGHERQAAEAARTE
LAKATLRLEAMPRLEAELAKERQGRIEAEQQAAVLTAQKADLEGRLVDAKKEAERTAA
QLQRAQERAEQQAEALADARVTIQTAQARAEDLAGQVEQARKDAKAAGEEAAILRGQI
AAQGERPASATAPKSKTPKA"
misc_feature 767..>982
/locus_tag="Tint_3200"
/note="Plasmid replication region DNA-binding N-term;
Region: KfrA_N; pfam11740"
/db_xref="CDD:204727"
gene 1688..1966
/locus_tag="Tint_3201"
/db_xref="GeneID:9153984"
CDS 1688..1966
/locus_tag="Tint_3201"
/inference="protein motif:PFAM:PF04365"
/note="PFAM: hypothetical protein;
KEGG: vei:Veis_2884 hypothetical protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644855.1"
/db_xref="GI:296137614"
/db_xref="InterPro:IPR007460"
/db_xref="GeneID:9153984"
/translation="MELEWDADKAARNMEKHGVSFEDAGLVFYDAGRIEAYDGREDYG
EDRWATIGLAYSAVLYVVYTVRHEDAIRLLSARKANADERKQYREANS"
misc_feature 1688..1960
/locus_tag="Tint_3201"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG2929"
/db_xref="CDD:32753"
gene 1926..2246
/locus_tag="Tint_3202"
/db_xref="GeneID:9153985"
CDS 1926..2246
/locus_tag="Tint_3202"
/inference="similar to AA sequence:KEGG:Veis_2885"
/note="KEGG: vei:Veis_2885 hypothetical protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644856.1"
/db_xref="GI:296137615"
/db_xref="GeneID:9153985"
/translation="MPTKESNIVKRTLDLKKPPVLSAEQKARLDAVASMPDEQIDYSD
APSLPAAVWLKAAAELPHIKQQITLRIDAEVLEFFKHTGKRYQSRINAVLRSYVDAHK
AHAK"
misc_feature 1980..2231
/locus_tag="Tint_3202"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG3514"
/db_xref="CDD:33317"
gene complement(2276..3103)
/locus_tag="Tint_3203"
/db_xref="GeneID:9153986"
CDS complement(2276..3103)
/locus_tag="Tint_3203"
/inference="ab initio prediction:Prodigal:1.4"
/note="KEGG: acr:Acry_3629 hypothetical protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644857.1"
/db_xref="GI:296137616"
/db_xref="GeneID:9153986"
/translation="MSKQAFDKLMGQLPDEDKKAIYAAAAAYGLDFESPEWIPFAISQ
HGLLAIQHAIEDLGAAVKEGSDHAIRQAMKAIHAAKDAELSEVEKAAAEIGAGLRKTA
ADGRQSLEAQAVKMTAQLTEQLTRTLQATAADIIARQVDPLNRAQQSLTRTVEAANAR
MAAAGRWFGAKAVVLALALTLIVGLAAWGLVGWERHEVSGLLAQQVQLQATIAQEQAT
VAALDKRGGRVRWSTCDGRLCFEVSGNQGQDSSGNPTPLGGWTTNGGKVALVIPRGY"
misc_feature complement(<2699..3013)
/locus_tag="Tint_3203"
/note="type I restriction enzyme EcoKI subunit R;
Provisional; Region: hsdR; PRK11448"
/db_xref="CDD:183141"
gene complement(3100..3876)
/locus_tag="Tint_3204"
/db_xref="GeneID:9153987"
CDS complement(3100..3876)
/locus_tag="Tint_3204"
/inference="similar to AA sequence:KEGG:Mrad2831_6487"
/note="KEGG: mrd:Mrad2831_6487 hypothetical protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644858.1"
/db_xref="GI:296137617"
/db_xref="GeneID:9153987"
/translation="MKRFVMVLTDKGGTGKSTMTRAIADRYARDGIKALLVDGDGEVG
QLYQHYCKLDEDGNPATQNAGDGVMTMRVTGEEKERDKLLAMLDYDLPVVLVDMPAAS
ITALAKFDAEVGFFDELQRSGYRPTMVNVLSPFQSSTRTVQQMVDLAGKSADYVAVVN
RWFGDDEDFYMWFGDGNGNPPSRGRAMLPDYGGEEIDLPKLQAGVMVAIDDRMMRFAD
AAADGSPLSRAQRSRLIRWMKDTDAQLDKVADKIGLGAGK"
misc_feature complement(<3757..3864)
/locus_tag="Tint_3204"
/note="ParA and ParB of Caulobacter crescentus belong to a
conserved family of bacterial proteins implicated in
chromosome segregation. ParB binds to DNA sequences
adjacent to the origin of replication and localizes to
opposite cell poles shortly following the...; Region:
ParA; cd02042"
/db_xref="CDD:73302"
misc_feature complement(3826..3846)
/locus_tag="Tint_3204"
/note="P-loop; other site"
/db_xref="CDD:73302"
misc_feature complement(3826..3828)
/locus_tag="Tint_3204"
/note="Magnesium ion binding site [ion binding]; other
site"
/db_xref="CDD:73302"
gene complement(3873..4283)
/locus_tag="Tint_3205"
/db_xref="GeneID:9153988"
CDS complement(3873..4283)
/locus_tag="Tint_3205"
/inference="similar to AA sequence:KEGG:Bxe_C0473"
/note="KEGG: bxe:Bxe_C0473 hypothetical protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644859.1"
/db_xref="GI:296137618"
/db_xref="GeneID:9153988"
/translation="MAGKPKTFTMKARDDVASIIASLPEKPKADKGLAAKDIITSLKA
EIRTAQEKGYTIEEIVQSFKQGGVDIGLTTLKAAMRQSTKKRPAKAAKKVEYEGGNSA
APQARRTVTPEERQVLRDETETTLTPAASKRGMR"
gene 4605..4904
/locus_tag="Tint_3206"
/db_xref="GeneID:9153989"
CDS 4605..4904
/locus_tag="Tint_3206"
/inference="similar to AA sequence:KEGG:PSPTO_1092"
/note="KEGG: pst:PSPTO_1092 mobilization protein MobB"
/codon_start=1
/transl_table=11
/product="mobilization protein MobB"
/protein_id="YP_003644860.1"
/db_xref="GI:296137619"
/db_xref="GeneID:9153989"
/translation="MSNSDSRKRTLALAVRVTPEEADAIMEKARDAGATVSEFLRACA
LGRKTRNTVDSQVINELRRLGGLQKHLFLEGGGANSYEHAAILIEIKKAVARIAT"
misc_feature 4605..>4811
/locus_tag="Tint_3206"
/note="conjugal transfer relaxosome component TraJ;
Provisional; Region: PRK13877"
/db_xref="CDD:184361"
misc_feature <4632..>4712
/locus_tag="Tint_3206"
/note="This domain superfamily is found in a variety of
structurally related metalloproteins, including the type I
extradiol dioxygenases, glyoxalase I and a group of
antibiotic resistance proteins; Region: Glo_EDI_BRP_like;
cl14632"
/db_xref="CDD:211465"
gene 4901..7000
/locus_tag="Tint_3207"
/db_xref="GeneID:9153990"
CDS 4901..7000
/locus_tag="Tint_3207"
/inference="protein motif:PFAM:PF03432"
/note="PFAM: Relaxase/mobilization nuclease family
protein;
KEGG: bvi:Bcep1808_7634 relaxase/mobilization nuclease
family protein"
/codon_start=1
/transl_table=11
/product="Relaxase/mobilization nuclease family protein"
/protein_id="YP_003644861.1"
/db_xref="GI:296137620"
/db_xref="InterPro:IPR005094"
/db_xref="GeneID:9153990"
/translation="MIPKVVPHRGDGNSSWRQAVEYVSRHSPEREAELDREAGDIDRT
AAELARDIELAGRYDDEAALSHPSRDATLRAAYDAELSADGPPPSKARTLSQAPTLGR
VGVLRLEGQEEEHAKVKDEAEYGRDPSRPTMFTNCLSVRTAHAEMKAVSDMCSRAKDP
VYHTLLSWRPGERPSDAQMFEAGHASMKAVGMEGHQYVFAVHRDTGNDHLHMLINRVN
PETYKAVYPSRDFYKLDRVCREVELAQGWEHDKGQYAVIDRDGQKAIVRASKETRMQE
KRPTKARDMEEVGGQESLFSYARGEPRQAVAALLKDPRTSWQDLHGELAKHGLELREK
GQGLAIYDKTHPERTPIKASDMHEGLGRGKLVKRLGEYQPPIRAIQIEQPARSYDKHR
EPARDPSRRDQAREERAQARARLRQQYDEWLSEQTKARQQSRAALRTGDRARFTDLAA
HHKARREQIRRTDMPAPMRKALYSVAAMEALQAREQLRAELDDKRKAERADRPQNFRE
WTGDRAQEGDQAAISQLRGWAYADRRRAKELEKAEQENAKKDGITIEAPAGRQEPLSP
RRLAMLDQLGYQVDRRTGDVHYQAKERHVFTDSGRRITFSAAGATDREALAAGLALAR
QKFGQTLTLTGSEQFKDEAIRVTVEKRLDVRLADPALEARRKVLEAARDVAKPHPRER
AQERNQVPDKGRGGQER"
misc_feature 5300..>6988
/locus_tag="Tint_3207"
/note="conjugal transfer relaxase TraI; Provisional;
Region: PRK13878"
/db_xref="CDD:184362"
misc_feature 5303..5962
/locus_tag="Tint_3207"
/note="Relaxase/Mobilisation nuclease domain; Region:
Relaxase; cl01584"
/db_xref="CDD:174650"
gene complement(7008..7697)
/locus_tag="Tint_3208"
/db_xref="GeneID:9153991"
CDS complement(7008..7697)
/locus_tag="Tint_3208"
/inference="ab initio prediction:Prodigal:1.4"
/note="KEGG: dsa:Desal_2365 non-hypothetical protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644862.1"
/db_xref="GI:296137621"
/db_xref="InterPro:IPR005587"
/db_xref="GeneID:9153991"
/translation="MAAKSERFELRIDEEQLARVDEWASEQPDQPTRAEAVRRLVNLG
LSAGSSRAVHFSDGEKMLILMMGDLFKALKIKDPESNPDFLAQVIYGGHYWAPKWDMQ
GVFHDHVDNPRDVSYVVDVLDMWSFIEEAYERLNSEQKAAIAAEVDEWATDVKFHGFD
GNNECGQMSIAGFLVNKMGRFSRFKGRDLNSHCQTEGRYRRMITAFEPMRASLVGGGL
NVQQLVTLLKR"
misc_feature complement(7080..>7346)
/locus_tag="Tint_3208"
/note="YfbU domain; Region: YfbU; cl01137"
/db_xref="CDD:186352"
gene 7978..9657
/locus_tag="Tint_3209"
/db_xref="GeneID:9153992"
CDS 7978..9657
/locus_tag="Tint_3209"
/inference="protein motif:PFAM:PF00665"
/note="PFAM: Integrase catalytic region; Transposase-like
Mu;
KEGG: asa:ASA_P4G095 TniA protein"
/codon_start=1
/transl_table=11
/product="Integrase catalytic region"
/protein_id="YP_003644863.1"
/db_xref="GI:296137622"
/db_xref="InterPro:IPR001584"
/db_xref="InterPro:IPR012337"
/db_xref="InterPro:IPR015378"
/db_xref="GeneID:9153992"
/translation="MATDTPRIPEQGVATLPDEAWERARRRAEIIGPLAQSETVGHEA
ADTAAQALGLSRRQVYVLIRRARQGSGLVTDLVPGQSGGGKGKGRLPEPVERIIRELL
QRRFLTKQKRSLAAFHREVTQVCKAQKLRVPARNTVALRIASLDPRKVIRRREGQDAA
RDLQGVGGEPPAVTAPLEQVQIDHTVIDLIVVDERDRQPIGRPYLTLAIDVFTRCVLG
MVVTLEAPSAVSVGLCLVHVACDKRPWLEGLKVEMDWPMSGKPLLLYLDNAAEFKSEA
LRRGCEQHGIRLDYRPLGQPHYGGIVERIIGTAMQMIHDDLPGTTFSNPDQRGDYDSE
NKAALTLRELERWLTLAVGTYHGSVHNGLLQPPAARWAEAVARVGVPAVVTRATAFLV
DFLPILRRTLTRTGFVIDHIHYYADALKPWIARRDRLPAFLIRRDPRDISRIWVLEPE
GQHYLEIPYRTLSHPAVTLWEQRQALAKLRQQGREQVDESALFRMIGQMREIVTAAQK
ATRKARRDTDRRQHLKASVPPNKPTPPETDVSDPQADKQPPAKPFDQIEEW"
misc_feature 8503..8916
/locus_tag="Tint_3209"
/note="Integrase core domain; Region: rve; pfam00665"
/db_xref="CDD:201381"
misc_feature 9145..9339
/locus_tag="Tint_3209"
/note="Mu transposase, C-terminal; Region: Mu-transpos_C;
pfam09299"
/db_xref="CDD:117843"
gene 9660..10568
/locus_tag="Tint_3210"
/db_xref="GeneID:9153993"
CDS 9660..10568
/locus_tag="Tint_3210"
/inference="protein motif:PFAM:PF05621"
/note="PFAM: TniB family protein;
KEGG: xcv:XCV2342 transposition protein TniB"
/codon_start=1
/transl_table=11
/product="TniB family protein"
/protein_id="YP_003644864.1"
/db_xref="GI:296137623"
/db_xref="InterPro:IPR008868"
/db_xref="GeneID:9153993"
/translation="MDEYPIIDLSHLLQAAQGLARLPADERIQRLRADRWIGYPRAVE
ALNRLETLYAWPNKQRMPNLLLVGPTNNGKSMIVEKFRRTHPASADADQEHIPVLVVQ
MPSEPSVIRFYVALLAAMGAPLRPRPRLPEMEQLALALLRKVGVRMLVIDELHNVLAG
NSVNRREFLNLLRFLGNELRIPLVGVGTRDAYLAIRSDDQLENRFEPMMLPVWEANDD
CCSLLASFTASLPLRRPSSIATLDMARYLLTRCEGTIGELAHLLMAAAVAAVESGEEA
INHRTLSMADYTGPSERRRQFERELM"
misc_feature 9660..10565
/locus_tag="Tint_3210"
/note="P-loop containing Nucleoside Triphosphate
Hydrolases; Region: P-loop_NTPase; cl09099"
/db_xref="CDD:213113"
gene 10619..11782
/locus_tag="Tint_3211"
/db_xref="GeneID:9153994"
CDS 10619..11782
/locus_tag="Tint_3211"
/inference="protein motif:PFAM:PF06527"
/note="PFAM: TniQ family protein;
KEGG: bxe:Bxe_C1175 transposition protein TniQ"
/codon_start=1
/transl_table=11
/product="TniQ family protein"
/protein_id="YP_003644865.1"
/db_xref="GI:296137624"
/db_xref="InterPro:IPR009492"
/db_xref="GeneID:9153994"
/translation="MSSWLNRVALCYHMEVSELLEHDLGHGQADDMDTAPPQSLLTML
SRRSGIELDRLRCMSFAGWVPWLLDSLDDQIPDALETYTFQLSVLLPKLRRRTRSITS
WRAWLPSQPLHRACPLCLNNPANQAVLLAWKLPLMLSCPLHGCWLESYWGVPGRFLGW
ENADADPRTASDAIATMDRRTWQALTTGHVELPRRRIHAGLWFRLLRTLLDELNTPLS
ACGTYAGYLRLIWERCGYPLRAGQSLWRPYETLNLAVGLQMLEAAATAISLIEVRDIS
PPGEHAKLFWSEPQTEFTSGLPAKAPKPEPVNHWQRAVQAIDEAIIEARHNPETARSL
FALASYGRRDPASLERLRATFVKEGIPPEFLSHYEPDGPFACLRQNDGLSDNF"
misc_feature 10619..11059
/locus_tag="Tint_3211"
/note="TniQ; Region: TniQ; pfam06527"
/db_xref="CDD:203473"
gene 11843..12457
/locus_tag="Tint_3212"
/db_xref="GeneID:9153995"
CDS 11843..12457
/locus_tag="Tint_3212"
/inference="protein motif:PFAM:PF00239"
/note="PFAM: Resolvase domain;
KEGG: asa:ASA_P5G160 TniR protein"
/codon_start=1
/transl_table=11
/product="Resolvase domain protein"
/protein_id="YP_003644866.1"
/db_xref="GI:296137625"
/db_xref="InterPro:IPR006118"
/db_xref="InterPro:IPR006119"
/db_xref="InterPro:IPR009057"
/db_xref="GeneID:9153995"
/translation="MLIGYMRVSKADGSQATDLQRDALIAAAIDPAHLYEDQASGKRE
DRPGLASCLKALRSGDTLVVWKLDRLGRDLRHLINTVHDLTGRGVGLKVLTGHGAAID
TTTAAGKLVFGIFAALAEFERELIAERTVAGLASARARGRKGGRPFKMTAAKLRLAMA
AMGQTETNVGDLCQELGITRQTLYRHISPKGELRADGIRLLSKV"
misc_feature 11843..12421
/locus_tag="Tint_3212"
/note="multiple promoter invertase; Provisional; Region:
mpi; PRK13413"
/db_xref="CDD:184041"
misc_feature 11846..12232
/locus_tag="Tint_3212"
/note="Serine Recombinase (SR) family, Resolvase and
Invertase subfamily, catalytic domain; members contain a
C-terminal DNA binding domain. Serine recombinases
catalyze site-specific recombination of DNA molecules by a
concerted, four-strand cleavage and...; Region: SR_ResInv;
cd03768"
/db_xref="CDD:58117"
misc_feature order(11861..11863,11867..11869,12044..12049,12056..12058)
/locus_tag="Tint_3212"
/note="catalytic residues [active]"
/db_xref="CDD:58117"
misc_feature 11867..11869
/locus_tag="Tint_3212"
/note="catalytic nucleophile [active]"
/db_xref="CDD:58117"
misc_feature order(12041..12043,12182..12187,12191..12196,12206..12208)
/locus_tag="Tint_3212"
/note="Presynaptic Site I dimer interface [polypeptide
binding]; other site"
/db_xref="CDD:58117"
misc_feature order(12059..12061,12074..12079,12170..12172,12179..12184,
12191..12196,12203..12205,12212..12214)
/locus_tag="Tint_3212"
/note="Synaptic Antiparallel dimer interface [polypeptide
binding]; other site"
/db_xref="CDD:58117"
misc_feature order(12128..12130,12140..12145,12170..12175,12182..12187,
12194..12196,12206..12208,12215..12217,12227..12229)
/locus_tag="Tint_3212"
/note="Synaptic Flat tetramer interface [polypeptide
binding]; other site"
/db_xref="CDD:58117"
misc_feature order(12128..12130,12185..12187,12194..12196,12206..12208,
12215..12217,12227..12229)
/locus_tag="Tint_3212"
/note="Synaptic Site I dimer interface [polypeptide
binding]; other site"
/db_xref="CDD:58117"
misc_feature order(12209..12211,12227..12232)
/locus_tag="Tint_3212"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:58117"
misc_feature 12281..12403
/locus_tag="Tint_3212"
/note="Helix-turn-helix domain of Hin and related
proteins, a family of DNA-binding domains unique to
bacteria and represented by the Hin protein of Salmonella.
The basic HTH domain is a simple fold comprised of three
core helices that form a right-handed...; Region:
HTH_Hin_like; cd00569"
/db_xref="CDD:119388"
misc_feature order(12281..12286,12383..12388,12392..12400)
/locus_tag="Tint_3212"
/note="DNA-binding interface [nucleotide binding]; DNA
binding site"
/db_xref="CDD:119388"
gene complement(12545..14491)
/locus_tag="Tint_3213"
/db_xref="GeneID:9153996"
CDS complement(12545..14491)
/locus_tag="Tint_3213"
/inference="protein motif:PFAM:PF03239"
/note="PFAM: iron permease FTR1; cytochrome c class I;
KEGG: rpf:Rpic12D_5282 iron permease FTR1"
/codon_start=1
/transl_table=11
/product="iron permease FTR1"
/protein_id="YP_003644867.1"
/db_xref="GI:296137626"
/db_xref="InterPro:IPR000629"
/db_xref="InterPro:IPR003088"
/db_xref="InterPro:IPR004923"
/db_xref="InterPro:IPR009056"
/db_xref="GeneID:9153996"
/translation="MPCRLPYRWLMALLLAICSLIGGPSYAANTTELKAKQIWQLLDY
VAVDYGGAVANGVVLKSSEYAEMQEFSATAERQLGELPDQTDKGRLLQQATALRAAVA
AKADPASVAKLAHALSSAVQKAYPFPVAPTAMPVLAKGGQLFQAQCAACHGQQGRGDG
PLAASLNPKPTALADHMRARERSLFALHQIISNGVQGTAMQGFGALSDEDRWALAFFV
GTLPYTQSDKDEGAKLWQANAQVRQTLVSLDVLTQTSEHVLADRLDEPSARALTAYLR
ANPSALNISSPKGTAIAKAKLSESVTALLADDRAGATKLALSAYLDGFEPVEPALATR
NRPLFEKIEAAMVSYRALIANGSPADVQTAELHLRGLLDEADKVLAPSDDDAVAAFIG
ALTILLREGLEALLVVVAMLAFLKKAERKDVLIYVHAGWASALAAGGITWAVATYLVG
VSGASRELTEGFSSLFAAVVLLGVGMWMHQKSVAGRWQVYLKEKLSSALNKRTAWFLF
SLAFVAVYREVFETVLFYAALWTEGNGWPLLAGLGTGMGILALLAVILLRTSARLPIG
QFFAASSLLVAILAVVLAGKGIAGLQEAGLLHTSPISIPRIDLLGIYPSWQTLSAQFA
VLFIVVVAFTINLRSSRQMAVQKS"
misc_feature complement(12596..>13207)
/locus_tag="Tint_3213"
/note="High-affinity Fe2+/Pb2+ permease [Inorganic ion
transport and metabolism]; Region: FTR1; COG0672"
/db_xref="CDD:31016"
gene complement(14510..15601)
/locus_tag="Tint_3214"
/db_xref="GeneID:9153997"
CDS complement(14510..15601)
/locus_tag="Tint_3214"
/EC_number="3.4.23.36"
/inference="protein motif:TFAM:TIGR00077"
/note="SMART: phosphoesterase PA-phosphatase related;
TIGRFAM: lipoprotein signal peptidase;
KEGG: shn:Shewana3_4320 signal peptidase II;
PFAM: peptidase A8 signal peptidase II; phosphoesterase
PA-phosphatase related"
/codon_start=1
/transl_table=11
/product="lipoprotein signal peptidase"
/protein_id="YP_003644868.1"
/db_xref="GI:296137627"
/db_xref="InterPro:IPR000326"
/db_xref="InterPro:IPR001872"
/db_xref="InterPro:IPR016118"
/db_xref="GeneID:9153997"
/translation="MSWKLFLYDWGGLNIALFQVINTGTPATLEPLAWFFSLVGSYWT
APLMLLGLWWWSKSATNAARGTAVRHRLIGFSAAFLLALLVATVLKLWFDFPRPPAVL
GELVRVIGDKELHYSLPSGHATYAALVVGALWPLMGRHGRVGLVLYATLVGWSRIAAG
MHFPADVLAGWALGWSCTALARWLLPLAASVWQSARRTSAWIWFTVAATIVMTDQLTK
FAIIRTFAYGEQVEITPFFNLVHVLNPGAAFSFLANAGGWQRYFFITLGLVVSAWLGR
MLCQQRPRLEAMGYSLILGGALGNVADRMLRGQVVDFLDFHWRLAHWPAFNLADVAIT
SGAALLIMQMQTREKRMDTGSIANYNHSQ"
misc_feature complement(15041..>15328)
/locus_tag="Tint_3214"
/note="PAP2_like_2 proteins. PAP2 is a super-family of
phosphatases and haloperoxidases. This subgroup, which is
specific to bacteria, lacks functional characterization
and may act as a membrane-associated lipid phosphatase;
Region: PAP2_like_2; cd03392"
/db_xref="CDD:48096"
misc_feature complement(order(15104..15106,15116..15118,15134..15136,
15236..15244,15311..15313))
/locus_tag="Tint_3214"
/note="active site"
/db_xref="CDD:48096"
misc_feature complement(14570..15013)
/locus_tag="Tint_3214"
/note="lipoprotein signal peptidase; Reviewed; Region:
lspA; PRK00376"
/db_xref="CDD:178992"
misc_feature complement(14576..14992)
/locus_tag="Tint_3214"
/note="lipoprotein signal peptidase; Provisional; Region:
PRK14787"
/db_xref="CDD:173248"
gene complement(15598..18003)
/locus_tag="Tint_3215"
/db_xref="GeneID:9153998"
CDS complement(15598..18003)
/locus_tag="Tint_3215"
/inference="protein motif:TFAM:TIGR01525"
/note="KEGG: sfr:Sfri_3462 heavy metal translocating
P-type ATPase;
TIGRFAM: heavy metal translocating P-type ATPase;
cadmium-translocating P-type ATPase; ATPase, P-type
(transporting), HAD superfamily, subfamily IC;
PFAM: E1-E2 ATPase-associated domain protein; Haloacid
dehalogenase domain protein hydrolase"
/codon_start=1
/transl_table=11
/product="heavy metal translocating P-type ATPase"
/protein_id="YP_003644869.1"
/db_xref="GI:296137628"
/db_xref="InterPro:IPR000150"
/db_xref="InterPro:IPR001366"
/db_xref="InterPro:IPR001757"
/db_xref="InterPro:IPR005834"
/db_xref="InterPro:IPR006121"
/db_xref="InterPro:IPR006404"
/db_xref="InterPro:IPR006416"
/db_xref="InterPro:IPR008250"
/db_xref="InterPro:IPR018303"
/db_xref="GeneID:9153998"
/translation="MSECASKGCGCSTGPIIQPTAQAPLATGSAQAVYRIENMDCPTE
EALIRGKLAGLAGVVGLEFNLMQRTLAVRHELPSLSPVEQALAAIGMQAVRMDQASTE
KTTKLSIAKMDCPTEEALIRNKLGTVAGVADLDFNLMQRTLSVRHADQVLPNVLAALQ
ALGFEAQVMDTAESASPSASPVITPTNWWPLGISLLTALAAEAVYWLHNGNHWSVVVL
ALVSVFTGGLSTYKKGWIALKNLNLNMNALMSIAVTGAMLIGHWPEAAMVMVLFALAE
VIEAKSLDRARNAIRGLLDMTPEQATVQQADGTWREVSAKQIAIGSRVRVKPGERIAL
DGEVLEGRSTVNQAPITGESLPVEKSPGDPVFAGTINESGSFEYRVTAVASNSTLARI
IHAVEAAQGSRAPTQRFVDQFARWYTPIVFALAIAVALLPPLFMGAAWLDWIYRALVL
LVVACPCALVISTPVSIVSGLAAAARHGILIKGGVYLEEGRKLRWLALDKTGTITHGK
PAQTDFVTWGNALASDSRSIAASLAARSDHPVSKAVAQAAQTDGVALLDVAEFNALPG
RGVQGQIDGETYYLGNHRMLEELGQCTPELEQRIAALETVGKTVVMLVGAKGVHALFA
VADTIKDSSRRAIAELHALGINTVMLTGDNPHTAQAIAAQAGIDRAQGNQLPDDKLRE
VEQLSRNGKVGMVGDGINDAPALARADIGFAMGAAGTDTAIETADVALMDDDLRKIPT
FVRLSRATAQVLMQNIVLALGIKAVFLVLTFTGHATMWMAVFADMGASLLVVGNGLRL
LRR"
misc_feature complement(15640..17697)
/locus_tag="Tint_3215"
/note="Cation transport ATPase [Inorganic ion transport
and metabolism]; Region: ZntA; COG2217"
/db_xref="CDD:32399"
misc_feature complement(17506..17688)
/locus_tag="Tint_3215"
/note="Heavy-metal-associated domain (HMA) is a conserved
domain of approximately 30 amino acid residues found in a
number of proteins that transport or detoxify heavy
metals, for example, the CPx-type heavy metal ATPases and
copper chaperones. HMA domain...; Region: HMA; cd00371"
/db_xref="CDD:29471"
misc_feature complement(order(17653..17655,17662..17670))
/locus_tag="Tint_3215"
/note="metal-binding site [ion binding]"
/db_xref="CDD:29471"
misc_feature complement(16537..17205)
/locus_tag="Tint_3215"
/note="E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122"
/db_xref="CDD:201018"
misc_feature complement(15889..16284)
/locus_tag="Tint_3215"
/note="haloacid dehalogenase-like hydrolase; Region: HAD;
pfam12710"
/db_xref="CDD:205034"
gene 18089..18508
/locus_tag="Tint_3216"
/db_xref="GeneID:9153999"
CDS 18089..18508
/locus_tag="Tint_3216"
/inference="protein motif:TFAM:TIGR02047"
/note="TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional
regulator;
PFAM: Transcription regulator MerR DNA binding; regulatory
protein MerR;
KEGG: app:CAP2UW1_4508 MerR family transcriptional
regulator;
SMART: regulatory protein MerR"
/codon_start=1
/transl_table=11
/product="MerR family transcriptional regulator"
/protein_id="YP_003644870.1"
/db_xref="GI:296137629"
/db_xref="InterPro:IPR000551"
/db_xref="InterPro:IPR009061"
/db_xref="InterPro:IPR011791"
/db_xref="InterPro:IPR015358"
/db_xref="GeneID:9153999"
/translation="MEIRIGDLAKRSGCEVVTIRYYEKEGLLPKPARSGGNFRLYSDV
HIERLQFIRHCRSLDMTLSEIRILLGLRDNPAQDCGDVNALLDVHIRQTEERVEALLQ
LKRHLLSLREKCSGARRIEACGILQGLSDCDHPGCNA"
misc_feature 18095..18475
/locus_tag="Tint_3216"
/note="Cd(II)/Pb(II)-responsive transcriptional regulator;
Region: CadR-PbrR; TIGR02047"
/db_xref="CDD:131102"
misc_feature 18095..18475
/locus_tag="Tint_3216"
/note="Helix-Turn-Helix DNA binding domain of the CadR and
PbrR transcription regulators; Region: HTH_CadR-PbrR;
cd04784"
/db_xref="CDD:133411"
misc_feature order(18098..18106,18146..18148,18197..18205)
/locus_tag="Tint_3216"
/note="DNA binding residues [nucleotide binding]"
/db_xref="CDD:133411"
misc_feature order(18239..18241,18248..18250,18260..18265,18290..18292,
18323..18328,18335..18337,18344..18346,18356..18358,
18374..18376,18386..18388,18395..18400,18419..18421,
18434..18439,18455..18457,18461..18463)
/locus_tag="Tint_3216"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:133411"
misc_feature order(18323..18325,18428..18430,18455..18457)
/locus_tag="Tint_3216"
/note="putative metal binding site [ion binding]; other
site"
/db_xref="CDD:133411"
gene 18750..19094
/locus_tag="Tint_3217"
/db_xref="GeneID:9154000"
CDS 18750..19094
/locus_tag="Tint_3217"
/inference="protein motif:PFAM:PF00239"
/note="PFAM: Resolvase domain;
KEGG: pna:Pnap_4991 resolvase domain-containing protein"
/codon_start=1
/transl_table=11
/product="Resolvase domain protein"
/protein_id="YP_003644871.1"
/db_xref="GI:296137630"
/db_xref="InterPro:IPR006118"
/db_xref="InterPro:IPR006119"
/db_xref="GeneID:9154000"
/translation="MGQRIGYARVSTDDQNLDLQHDALRKAGIADDRLYSDTASGKDA
DRKELLACLKALREGDTLVVWRLDRLGRSLPDLVRIVGELEHRGVSFESLTEPPRLSW
RPVGLSQATVVT"
misc_feature 18759..>19040
/locus_tag="Tint_3217"
/note="Serine Recombinase (SR) family, Resolvase and
Invertase subfamily, catalytic domain; members contain a
C-terminal DNA binding domain. Serine recombinases
catalyze site-specific recombination of DNA molecules by a
concerted, four-strand cleavage and...; Region: SR_ResInv;
cd03768"
/db_xref="CDD:58117"
misc_feature 18762..>19040
/locus_tag="Tint_3217"
/note="Site-specific recombinases, DNA invertase Pin
homologs [DNA replication, recombination, and repair];
Region: PinR; COG1961"
/db_xref="CDD:32144"
misc_feature order(18774..18776,18780..18782,18951..18956,18963..18965)
/locus_tag="Tint_3217"
/note="catalytic residues [active]"
/db_xref="CDD:58117"
misc_feature 18780..18782
/locus_tag="Tint_3217"
/note="catalytic nucleophile [active]"
/db_xref="CDD:58117"
gene complement(19073..19981)
/locus_tag="Tint_3218"
/db_xref="GeneID:9154001"
CDS complement(19073..19981)
/locus_tag="Tint_3218"
/inference="protein motif:PFAM:PF00665"
/note="KEGG: afe:Lferr_1426 integrase catalytic region;
manually curated;
PFAM: Integrase catalytic region"
/codon_start=1
/transl_table=11
/product="Integrase catalytic region"
/protein_id="YP_003644872.1"
/db_xref="GI:296137631"
/db_xref="InterPro:IPR001584"
/db_xref="InterPro:IPR012337"
/db_xref="GeneID:9154001"
/translation="MRNFVDEHRQAFGVEPICKVLQIAPSGYRLHAARQRNPALLSPR
AQRDQRLIPHVQQVWQANLQVYGVDKVYKQMNREGVAVARCTVERLMRRLGLRGAIRG
KVVRTTIADAKAPCPLDHVNRVFKAERPNQLWVSDFTYVSTWQGWLYVAFVIDVFARR
IVGWRVSSSMRTDFVLDALEQALYARQPEQNETLIHHSDRGSQYVSIRYTERLAEAGI
EPSVGSKGDSYDNALAETINGLYKAELIHRRAPWKTKESVELATLEWVAWFNHHRLME
PLGYIPPAEAEANYWRQQASHVTTVA"
misc_feature complement(19103..19921)
/locus_tag="Tint_3218"
/note="putative transposase OrfB; Reviewed; Region:
PHA02517"
/db_xref="CDD:177368"
misc_feature complement(19673..19846)
/locus_tag="Tint_3218"
/note="HTH-like domain; Region: HTH_21; pfam13276"
/db_xref="CDD:205456"
misc_feature complement(19247..19594)
/locus_tag="Tint_3218"
/note="Integrase core domain; Region: rve; pfam00665"
/db_xref="CDD:201381"
misc_feature complement(19133..19333)
/locus_tag="Tint_3218"
/note="Integrase core domain; Region: rve_3; pfam13683"
/db_xref="CDD:205859"
gene complement(19978..20301)
/locus_tag="Tint_3219"
/db_xref="GeneID:9154002"
CDS complement(19978..20301)
/locus_tag="Tint_3219"
/inference="protein motif:PFAM:PF01527"
/note="PFAM: transposase IS3/IS911 family protein;
KEGG: dia:Dtpsy_3254 transposase IS3/IS911 family protein"
/codon_start=1
/transl_table=11
/product="transposase IS3/IS911 family protein"
/protein_id="YP_003644873.1"
/db_xref="GI:296137632"
/db_xref="InterPro:IPR002514"
/db_xref="GeneID:9154002"
/translation="MNKSTKFSPEVRERAVRMVQEHRGEYPSLWAAVESIAPKIGCSA
HTLLEWVRRDEVDAGTRPGVTSAEAQRVKELEREVKELRRANEILKLASAFFAQAELD
RRLKS"
misc_feature complement(20098..20301)
/locus_tag="Tint_3219"
/note="Helix-turn-helix domains; Region: HTH; cl00088"
/db_xref="CDD:213080"
gene 20308..20673
/locus_tag="Tint_3220"
/pseudo
/db_xref="GeneID:9154003"
gene 20670..26743
/locus_tag="Tint_3221"
/pseudo
/db_xref="GeneID:9154004"
gene 22381..22706
/locus_tag="Tint_3222"
/pseudo
/db_xref="GeneID:9154005"
gene 22703..23612
/locus_tag="Tint_3223"
/pseudo
/db_xref="GeneID:9154006"
gene 26810..29464
/locus_tag="Tint_3224"
/db_xref="GeneID:9154007"
CDS 26810..29464
/locus_tag="Tint_3224"
/inference="protein motif:PFAM:PF02463"
/note="PFAM: SMC domain protein;
KEGG: xoo:XOO4472 hypothetical protein"
/codon_start=1
/transl_table=11
/product="SMC domain protein"
/protein_id="YP_003644874.1"
/db_xref="GI:296137633"
/db_xref="InterPro:IPR003395"
/db_xref="GeneID:9154007"
/translation="MSDQYTYARFWRCALQVNPVGYNGTYRGADHGLDEGGYNQALLQ
KCLELGITVVGLADHGSVASVDALRQVLQPRGIVVFPGFEIASNDKTHYVCLFSEETT
GQQLERYLGNLDLLDPTDGVRPSRLSSEQLIEKVDQLGGFIYAAHCTSDSGLLKNRLN
HVWKLHKLRAAQIPGPIDDLAGVESDFYRRVLLNKDDAYRRERPVAVINAKDVAKPED
LEQPGATCFIKMTRPNFAAFKVAFLDPGSRIRLNSQQAQSPIGKVVRMTVAGGYLDGV
RVDFSDHLNTVIGGRGTGKSTLLECLRFALDLPPKGKQAQKLHQEIIKENLGRSAGRV
ELTVVSSAQNGKQYTISRRHGEPPMVRDMDGNVSTLLPRDLLPGIDIYGQNEIYELAQ
DETSRVQLLDRFLPQDGQYESKSADVHRRLKDNQQKLTKSLTDLDELNAQVERLPKLE
EQLRGFDELGIKEKLAKTSLLAREREIAKTATEGVQNFRDALTDLRDSLPDLDFINDE
ALEGLPDAAQLLAMRTTLDGLKQGFTGHLTAMQALLDDKAGQFTTQHDAWQQAIQAHD
VELEKALRTLPATAGKSGQEVGVAYQKLMGEIERIKPMKSRATTHESQRDTLRQERRN
LLAELSDLRAQRIQALQKAAKKLNRRLEGKLKVEIVPEADRTPLMTFLLGCKLDGVGE
KRLAFIEEAETISPLSLAQSIQKGSADVQLDWGVTQMVADALTKLQSSQLMELEALEL
EHRADIFLNVAHGQADPVFRPLNKLSTGQQCTAILHMLLLENVDPLLMDQPEDNLDNA
FIADRIVAELREAKTSRQFLFATHNANIPVFGDAEWIGVFTAAENQGRLGLEAQGSID
VPVIRDQVASILEGGRDAFIQRKEKYEF"
misc_feature 26933..>27262
/locus_tag="Tint_3224"
/note="PHP domain; Region: PHP; pfam02811"
/db_xref="CDD:202407"
misc_feature 27620..28168
/locus_tag="Tint_3224"
/note="AAA domain; Region: AAA_23; pfam13476"
/db_xref="CDD:205654"
misc_feature 27638..>27868
/locus_tag="Tint_3224"
/note="P-loop containing Nucleoside Triphosphate
Hydrolases; Region: P-loop_NTPase; cl09099"
/db_xref="CDD:213113"
misc_feature 27674..27697
/locus_tag="Tint_3224"
/note="Walker A/P-loop; other site"
/db_xref="CDD:72971"
misc_feature order(27683..27688,27692..27700)
/locus_tag="Tint_3224"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:72971"
misc_feature <28082..>28342
/locus_tag="Tint_3224"
/note="Ribosomal protein S2 (RPS2), involved in formation
of the translation initiation complex, where it might
contact the messenger RNA and several components of the
ribosome. It has been shown that in Escherichia coli RPS2
is essential for the binding of...; Region: RPS2; cl00315"
/db_xref="CDD:206978"
misc_feature <28988..29287
/locus_tag="Tint_3224"
/note="AAA domain; Region: AAA_21; pfam13304"
/db_xref="CDD:205484"
misc_feature <29087..29287
/locus_tag="Tint_3224"
/note="P-loop containing Nucleoside Triphosphate
Hydrolases; Region: P-loop_NTPase; cl09099"
/db_xref="CDD:213113"
misc_feature 29102..29131
/locus_tag="Tint_3224"
/note="ABC transporter signature motif; other site"
/db_xref="CDD:72971"
misc_feature 29162..29179
/locus_tag="Tint_3224"
/note="Walker B; other site"
/db_xref="CDD:72971"
misc_feature 29186..29197
/locus_tag="Tint_3224"
/note="D-loop; other site"
/db_xref="CDD:72971"
misc_feature 29261..29281
/locus_tag="Tint_3224"
/note="H-loop/switch region; other site"
/db_xref="CDD:72971"
gene complement(29577..29906)
/locus_tag="Tint_3225"
/db_xref="GeneID:9154008"
CDS complement(29577..29906)
/locus_tag="Tint_3225"
/inference="protein motif:TFAM:TIGR02385"
/note="KEGG: zmn:Za10_1846 addiction module toxin,
RelE/StbE family;
TIGRFAM: addiction module toxin, RelE/StbE family;
PFAM: plasmid stabilization system"
/codon_start=1
/transl_table=11
/product="addiction module toxin, RelE/StbE family"
/protein_id="YP_003644875.1"
/db_xref="GI:296137634"
/db_xref="InterPro:IPR007712"
/db_xref="InterPro:IPR012753"
/db_xref="GeneID:9154008"
/translation="MTSKKPAASKRANLPRASDYTKDFLKDWQRLSHSGRYDMNRLKE
AMTLLIANDGPLPPEWLDHALTGDWAGHRECHVGGDFLLIYTLDDSGKSGLVVFVRSG
THSELFS"
misc_feature complement(29583..29864)
/locus_tag="Tint_3225"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG3041"
/db_xref="CDD:32855"
gene complement(29878..30159)
/locus_tag="Tint_3226"
/db_xref="GeneID:9154009"
CDS complement(29878..30159)
/locus_tag="Tint_3226"
/inference="protein motif:TFAM:TIGR02384"
/note="KEGG: vei:Veis_2863 addiction module antitoxin;
TIGRFAM: addiction module antitoxin, RelB/DinJ family;
PFAM: RelB antitoxin"
/codon_start=1
/transl_table=11
/product="addiction module antitoxin, RelB/DinJ family"
/protein_id="YP_003644876.1"
/db_xref="GI:296137635"
/db_xref="InterPro:IPR007337"
/db_xref="GeneID:9154009"
/translation="MAATTTMVHVRVDENVKAQAAETLASMGLTVSDAIRVFLTRVVA
DKELPFALKAPNATSRVAIAEANEIIKSRRARFATADALLNDLEEASRK"
misc_feature complement(29899..30150)
/locus_tag="Tint_3226"
/note="RelB antitoxin; Region: RelB; cl01171"
/db_xref="CDD:212258"
gene complement(30288..30827)
/locus_tag="Tint_3227"
/db_xref="GeneID:9154010"
CDS complement(30288..30827)
/locus_tag="Tint_3227"
/inference="protein motif:PFAM:PF00929"
/note="KEGG: rme:Rmet_2846 exonuclease;
PFAM: Exonuclease RNase T and DNA polymerase III;
SMART: Exonuclease"
/codon_start=1
/transl_table=11
/product="Exonuclease RNase T and DNA polymerase III"
/protein_id="YP_003644877.1"
/db_xref="GI:296137636"
/db_xref="InterPro:IPR006055"
/db_xref="InterPro:IPR012337"
/db_xref="InterPro:IPR013520"
/db_xref="GeneID:9154010"
/translation="MTPVVLVIDLEATCDDADGLPASDMEIIEIGAVWATVEGSVLDT
FQALVRPVVRPQLTPFCRQLTNIQQADVDGAELFPAVAARLASFAQRHQAPGATWGSW
GQFDAKQLARDCERHGIESPLAAFEHVNLKRRFAKGRKIKEVGMARALQMVGLPLDGS
HHRGLDDARNIAKLLPWSL"
misc_feature complement(30297..30815)
/locus_tag="Tint_3227"
/note="DEDDh 3'-5' exonuclease domain of Caenorhabditis
elegans ERI-1, human 3' exonuclease, and similar proteins;
Region: ERI-1_3'hExo_like; cd06133"
/db_xref="CDD:99836"
misc_feature complement(order(30327..30329,30342..30344,30498..30500,
30510..30524,30648..30650,30786..30788,30792..30803))
/locus_tag="Tint_3227"
/note="active site"
/db_xref="CDD:99836"
misc_feature complement(order(30327..30329,30342..30344,30498..30500,
30510..30524,30648..30650,30786..30788,30792..30803))
/locus_tag="Tint_3227"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:99836"
misc_feature complement(order(30327..30329,30342..30344,30510..30512,
30795..30797,30801..30803))
/locus_tag="Tint_3227"
/note="catalytic site [active]"
/db_xref="CDD:99836"
gene complement(30824..31393)
/locus_tag="Tint_3228"
/db_xref="GeneID:9154011"
CDS complement(30824..31393)
/locus_tag="Tint_3228"
/inference="protein motif:TFAM:TIGR01509"
/note="KEGG: dma:DMR_07180 haloacid dehalogenase-like
hydrolase family protein;
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant
3; HAD-superfamily hydrolase, subfamily IA, variant 1;
PFAM: Haloacid dehalogenase domain protein hydrolase"
/codon_start=1
/transl_table=11
/product="HAD-superfamily hydrolase, subfamily IA, variant
3"
/protein_id="YP_003644878.1"
/db_xref="GI:296137637"
/db_xref="InterPro:IPR005833"
/db_xref="InterPro:IPR005834"
/db_xref="InterPro:IPR006402"
/db_xref="InterPro:IPR006439"
/db_xref="GeneID:9154011"
/translation="MKPTRAIVFDAFGTLIRYTTRPAPYGHLVDAAGRPVDRIACLTR
DVPLATLAVELGVESSLDIMEADLAEELSGLRLFPEVADVLVKARAAGLRLAVCSNLA
YEYGPAVRGLLPELDAYVLSYEVGVAKPHPTMYRLACAELGCAPAETVFVGDSKRCDF
DGPQAFGMQARWLDRRGGQSLVDALAGIL"
misc_feature complement(30875..31375)
/locus_tag="Tint_3228"
/note="Haloacid dehalogenase-like hydrolase; Region:
HAD_2; pfam13419"
/db_xref="CDD:205597"
misc_feature complement(30884..31201)
/locus_tag="Tint_3228"
/note="Haloacid dehalogenase-like hydrolases. The haloacid
dehalogenase-like (HAD) superfamily includes L-2-haloacid
dehalogenase, epoxide hydrolase, phosphoserine
phosphatase, phosphomannomutase, phosphoglycolate
phosphatase, P-type ATPase, and many others; Region:
HAD_like; cd01427"
/db_xref="CDD:119389"
misc_feature complement(31097..31099)
/locus_tag="Tint_3228"
/note="motif II; other site"
/db_xref="CDD:119389"
gene complement(31426..31629)
/locus_tag="Tint_3229"
/db_xref="GeneID:9154012"
CDS complement(31426..31629)
/locus_tag="Tint_3229"
/inference="ab initio prediction:Prodigal:1.4"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644879.1"
/db_xref="GI:296137638"
/db_xref="GeneID:9154012"
/translation="MRFWTFDPNTCRFERASKQAALHAADVAVVNDDTDVQVISDHQP
PKRWPSGEPLVVAGVEFERELFE"
gene complement(31631..32185)
/locus_tag="Tint_3230"
/db_xref="GeneID:9154013"
CDS complement(31631..32185)
/locus_tag="Tint_3230"
/inference="ab initio prediction:Prodigal:1.4"
/note="KEGG: xcv:XCV1305 hypothetical protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644880.1"
/db_xref="GI:296137639"
/db_xref="GeneID:9154013"
/translation="MQFKTVRHRDQDGNYHEGKTVQCLRRVREVTPDFPEGKNVQRVV
AKFDRAARELPAEVAAVLTPAEQDEWKEWRVKQDEEHLKSVAQYELDTLAERLGVIRT
GIQKGYAATDNKNAVAIRNGTRAVLRLLADLMPEPVKGRPVIEEEYEPLMLPNFATPG
TPEFDSYQRLLEEHERRKAQDQGG"
gene 32384..33010
/locus_tag="Tint_3231"
/db_xref="GeneID:9154014"
CDS 32384..33010
/locus_tag="Tint_3231"
/inference="protein motif:PFAM:PF01656"
/note="PFAM: Cobyrinic acid ac-diamide synthase;
KEGG: xcv:XCVc0005 putative partition protein"
/codon_start=1
/transl_table=11
/product="Cobyrinic acid ac-diamide synthase"
/protein_id="YP_003644881.1"
/db_xref="GI:296137640"
/db_xref="InterPro:IPR002586"
/db_xref="GeneID:9154014"
/translation="MIFACVNTKGGVGKTTTAVHLAVMLARQGKTLLIDGDPQASAAS
WAAWRRETQYDPSPTTTCLAGKAILAEGKQLASGFEHVVVDAGGRDSVGLRSALLLAQ
RAVIPIGASNLDAAAMTDLLEVVELARDYNPELDVRVLLTRVDPRTKDAAEMLEFLAE
QKLTVLPTKVCERVAFRRAIGEGASVQELGRDQAAIAEMEAFFKEVMA"
misc_feature 32384..32998
/locus_tag="Tint_3231"
/note="ParA-like protein; Provisional; Region: PHA02518"
/db_xref="CDD:134018"
misc_feature 32387..32809
/locus_tag="Tint_3231"
/note="ParA and ParB of Caulobacter crescentus belong to a
conserved family of bacterial proteins implicated in
chromosome segregation. ParB binds to DNA sequences
adjacent to the origin of replication and localizes to
opposite cell poles shortly following the...; Region:
ParA; cd02042"
/db_xref="CDD:73302"
misc_feature 32408..32428
/locus_tag="Tint_3231"
/note="P-loop; other site"
/db_xref="CDD:73302"
misc_feature order(32426..32428,32636..32638)
/locus_tag="Tint_3231"
/note="Magnesium ion binding site [ion binding]; other
site"
/db_xref="CDD:73302"
gene 33007..33333
/locus_tag="Tint_3232"
/db_xref="GeneID:9154015"
CDS 33007..33333
/locus_tag="Tint_3232"
/inference="similar to AA sequence:KEGG:XACb0018"
/note="KEGG: xac:XACb0018 hypothetical protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644882.1"
/db_xref="GI:296137641"
/db_xref="GeneID:9154015"
/translation="MSMKGKPNTAQFKPPKDPTAFLEGGEADKAEKPLVAPAAVTTPP
AATPPAAEETQRYGRARVQKIFNFPEELADRLRREALKRSEEKGGRVTEKDIVIEALE
AFLKGR"
gene 33478..33789
/locus_tag="Tint_3233"
/db_xref="GeneID:9154016"
CDS 33478..33789
/locus_tag="Tint_3233"
/inference="similar to AA sequence:KEGG:XACb0017"
/note="KEGG: xac:XACb0017 partition protein C"
/codon_start=1
/transl_table=11
/product="partition protein C"
/protein_id="YP_003644883.1"
/db_xref="GI:296137642"
/db_xref="GeneID:9154016"
/translation="MLTTTASVVAPKVLKELIAAGSVSAARVEPGDKGLLIVVRAGMN
ERVLGAARGGLRYFQSLDGAASVLQSYGIMKFDVNTEHWVPKTMVRGYKQAPASVDAD
E"
gene 34037..35257
/locus_tag="Tint_3234"
/db_xref="GeneID:9154017"
CDS 34037..35257
/locus_tag="Tint_3234"
/inference="protein motif:PFAM:PF03090"
/note="PFAM: plasmid replicase; Primase 1;
KEGG: xac:XACb0016 replication protein A"
/codon_start=1
/transl_table=11
/product="plasmid replicase"
/protein_id="YP_003644884.1"
/db_xref="GI:296137643"
/db_xref="InterPro:IPR004322"
/db_xref="InterPro:IPR014820"
/db_xref="GeneID:9154017"
/translation="MAGTTAQKLDNQTADRFFQSGTALNRVLTEAPYLPRCSDDKTAT
RVRPREYAIRYPYMQVNRPGFVSWLIFDLDHAKAMIWEDAGLPAPNLIVRNRQSGHSH
LYYAIPPVCTTEAARSKPIAYMKAVYEAFAARLDADTDFHSGPVAKTPGHPWWLTHEL
HAHVYELGELADYVDLAVSSPWGKGPQFDEVSHSRHCILFEHLRHYAYSIVNRERERG
SFATFTRLLEAYAHNRNSFQKLGFMDNLAQSSLKATVKSVARWTWDRYTGCGRCHRGV
MQLDKDLPLIERQRLAAARTHDVRHKTTESKVRAACRLLQQKGEALTQAAIGRVAGLT
RQTVATYKHVLEEVLKPVAVAILGGASGKAEDVKHGAHQVTAAPQGAGVLGAASVSLE
LFPAGPGVVPVLDG"
misc_feature 34160..34561
/locus_tag="Tint_3234"
/note="Replicase family; Region: Replicase; pfam03090"
/db_xref="CDD:111931"
misc_feature 34598..34828
/locus_tag="Tint_3234"
/note="Primase C terminal 1 (PriCT-1); Region: PriCT_1;
pfam08708"
/db_xref="CDD:204035"
gene 35467..35820
/locus_tag="Tint_3235"
/db_xref="GeneID:9154018"
CDS 35467..35820
/locus_tag="Tint_3235"
/inference="similar to AA sequence:KEGG:Tgr7_0908"
/note="KEGG: tgr:Tgr7_0908 hypothetical protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644885.1"
/db_xref="GI:296137644"
/db_xref="GeneID:9154018"
/translation="MARRSFDNETLAWVREMPLSQVLDKLRDDGQLFWRRDLDFVPEK
DKRTVRLFLSSPSGFAWEVLVTGLKWFDVRAGKGGGGGIDLVMHLLGIDFVKAVKLLS
SGAGVAGQRRPVRPQ"
gene 36304..36492
/locus_tag="Tint_3236"
/db_xref="GeneID:9154019"
CDS 36304..36492
/locus_tag="Tint_3236"
/inference="ab initio prediction:Prodigal:1.4"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644886.1"
/db_xref="GI:296137645"
/db_xref="GeneID:9154019"
/translation="MQTTKTTPYHCAEVRRSVPVFQRIEWVSGIGQDDAEPVVLAEAC
ALASRCPRVAHCPLTADE"
gene complement(36549..36656)
/locus_tag="Tint_3237"
/db_xref="GeneID:9154020"
CDS complement(36549..36656)
/locus_tag="Tint_3237"
/inference="ab initio prediction:Prodigal:1.4"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644887.1"
/db_xref="GI:296137646"
/db_xref="GeneID:9154020"
/translation="MRIIVIAHNGYPFRNNEHAVLIATGITHHIVLLKD"
gene complement(36739..39705)
/locus_tag="Tint_3238"
/db_xref="GeneID:9154021"
CDS complement(36739..39705)
/locus_tag="Tint_3238"
/inference="protein motif:PFAM:PF01526"
/note="PFAM: transposase Tn3 family protein;
KEGG: tmz:Tmz1t_2112 transposase Tn3 family protein"
/codon_start=1
/transl_table=11
/product="transposase Tn3 family protein"
/protein_id="YP_003644888.1"
/db_xref="GI:296137647"
/db_xref="InterPro:IPR002513"
/db_xref="GeneID:9154021"
/translation="MADGGGSKEDQWVLAPAERELVMTKNRANRLGFAILLTFFRDRG
RFPRDETEVEVQGIAALAKQLDAPAPIDGEAFLTGRTAERLRGEIRVRFGFREATVAD
AEMLTEWLRDHVAGEVGGDIEPMIERLEGRCRELAIEPPKPDRMERIARSALRSHEDR
FHSCVYGRLPPATRERLDALLRPEESGHGESAVEDAQGEAAGNAPAVLLKLRGSPGRP
SLASMQDELAKLELIRGIELSADLFDRTSPRDLERCRQRVSVEVPRDLRRHPDAARLT
WLAAFVHLRARSLTDDLVDLLIETIHQIGARAERKVERELLEDLKRVSGKQNLLFNLA
DATLAQPDGVVRDVVFPVVGEQTLRDLVKEWKATGPTYRITLRTVIRNSYQGHYRRIV
PTLLAALVFRSNNDRHRPVMDALALVKRFADTKVHTFPADIEVPLDGVVRGLWREAVM
ETDAAGRDRVNRVTYEIAVLEALRERLRCKEIWVVGANRYRNPDDDLPADFEQNREDY
YRALNLPLDVERFIADLQAEMRAALSTFDAGLKKNPSVRLSSKGGGWITLTPLDAQPD
PPNLTALKAELNVLWPMTSLLDMVKETDLRLSFTDALKSPTSYESMDRSVLQPRLLLC
LHGLGTNAGLQRMAGLDSGTTARDLAYVRRRYISVDAMRRAIAIVADGTLQARNPAIW
GSGTTACASDSKHFGAWDQNLTTQWHVRYGGRGVMIYWHVERSSLCIHSQLKSPSSSE
VASMIEGVIHHCTEMEVDRQYVDSHGQSTVAFAFCRLLGFQLLPRLKAIHSQKLYRPE
TGKADVYANLQQILTKPIDWDSVRQQYDQMVKYATALRLGTADTEAILRRFTKKNVQH
PTYKAFAELGKAIKTIFLCRYLHDEALRREINEGLNVVEQWNGATDFVFFARRGEMAS
NRREDHEVSMLALHLIQNCMVYINTLMIQKVLALPHWQGRFTPRDYAALTPLIWEHVN
PYGRFDLDMNTRLDLP"
misc_feature complement(39244..39666)
/locus_tag="Tint_3238"
/note="Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3;
cl14901"
/db_xref="CDD:209926"
misc_feature complement(36775..37944)
/locus_tag="Tint_3238"
/note="Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3;
pfam01526"
/db_xref="CDD:190022"
gene complement(39710..40285)
/locus_tag="Tint_3239"
/db_xref="GeneID:9154022"
CDS complement(39710..40285)
/locus_tag="Tint_3239"
/inference="protein motif:PFAM:PF00239"
/note="KEGG: tmz:Tmz1t_2111 resolvase domain protein;
PFAM: Resolvase domain;
SMART: Resolvase domain"
/codon_start=1
/transl_table=11
/product="Resolvase domain protein"
/protein_id="YP_003644889.1"
/db_xref="GI:296137648"
/db_xref="InterPro:IPR006118"
/db_xref="InterPro:IPR006119"
/db_xref="InterPro:IPR009057"
/db_xref="GeneID:9154022"
/translation="MRVSSDSDRQSTDLQRDALLAAGVDPRHLFEDYASGAKDDRAGL
VQALEFVRPGDVLVVWKLDRLGRSLSHLLTIVTSLKDKRVAFRSLTENLDTTTPSGEF
LFQVFGALAQYERALIQERVVAGLAAARKRGRIGGRPQAITGEKLDAIIAALEGGMSK
AAVCRNFGVKRTTLIETLTRAGWPASVPPGA"
misc_feature complement(39764..40285)
/locus_tag="Tint_3239"
/note="multiple promoter invertase; Provisional; Region:
mpi; PRK13413"
/db_xref="CDD:184041"
misc_feature complement(39920..40285)
/locus_tag="Tint_3239"
/note="Serine Recombinase (SR) family, Resolvase and
Invertase subfamily, catalytic domain; members contain a
C-terminal DNA binding domain. Serine recombinases
catalyze site-specific recombination of DNA molecules by a
concerted, four-strand cleavage and...; Region: SR_ResInv;
cd03768"
/db_xref="CDD:58117"
misc_feature complement(order(40085..40087,40094..40099,40274..40276,
40280..40282))
/locus_tag="Tint_3239"
/note="catalytic residues [active]"
/db_xref="CDD:58117"
misc_feature complement(40274..40276)
/locus_tag="Tint_3239"
/note="catalytic nucleophile [active]"
/db_xref="CDD:58117"
misc_feature complement(order(39944..39946,39956..39961,39965..39970,
40100..40102))
/locus_tag="Tint_3239"
/note="Presynaptic Site I dimer interface [polypeptide
binding]; other site"
/db_xref="CDD:58117"
misc_feature complement(order(39938..39940,39947..39949,39956..39961,
39968..39973,39980..39982,40064..40069,40082..40084))
/locus_tag="Tint_3239"
/note="Synaptic Antiparallel dimer interface [polypeptide
binding]; other site"
/db_xref="CDD:58117"
misc_feature complement(order(39923..39925,39935..39937,39944..39946,
39956..39958,39965..39970,39977..39982,40007..40015))
/locus_tag="Tint_3239"
/note="Synaptic Flat tetramer interface [polypeptide
binding]; other site"
/db_xref="CDD:58117"
misc_feature complement(order(39923..39925,39935..39937,39944..39946,
39956..39958,39965..39967,40013..40015))
/locus_tag="Tint_3239"
/note="Synaptic Site I dimer interface [polypeptide
binding]; other site"
/db_xref="CDD:58117"
misc_feature complement(order(39920..39925,39941..39943))
/locus_tag="Tint_3239"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:58117"
misc_feature complement(39764..39871)
/locus_tag="Tint_3239"
/note="Helix-turn-helix domain of Hin and related
proteins, a family of DNA-binding domains unique to
bacteria and represented by the Hin protein of Salmonella.
The basic HTH domain is a simple fold comprised of three
core helices that form a right-handed...; Region:
HTH_Hin_like; cd00569"
/db_xref="CDD:119388"
misc_feature complement(order(39767..39772,39866..39871))
/locus_tag="Tint_3239"
/note="DNA-binding interface [nucleotide binding]; DNA
binding site"
/db_xref="CDD:119388"
gene 40539..40817
/locus_tag="Tint_3240"
/db_xref="GeneID:9154023"
CDS 40539..40817
/locus_tag="Tint_3240"
/inference="similar to AA sequence:KEGG:Rmet_6342"
/note="KEGG: rme:Rmet_6342 hypothetical protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644890.1"
/db_xref="GI:296137649"
/db_xref="GeneID:9154023"
/translation="MSKQAVFTMKLEPELRAEFMAEAEAAHRPASQVLRELMREFVQR
QRESREYDEFLRRKVEAGRASMRAGLGRSNDEVEAEFAARRASVARQS"
gene 40814..41098
/locus_tag="Tint_3241"
/db_xref="GeneID:9154024"
CDS 40814..41098
/locus_tag="Tint_3241"
/inference="protein motif:TFAM:TIGR02385"
/note="KEGG: rme:Rmet_6341 addiction module toxin,
RelE/StbE;
TIGRFAM: addiction module toxin, RelE/StbE family;
PFAM: plasmid stabilization system"
/codon_start=1
/transl_table=11
/product="addiction module toxin, RelE/StbE family"
/protein_id="YP_003644891.1"
/db_xref="GI:296137650"
/db_xref="InterPro:IPR007712"
/db_xref="InterPro:IPR012753"
/db_xref="GeneID:9154024"
/translation="MRVVWTPEAQQDRADVWDYIAADNPRAAARMDEIFSDAAARLIQ
HPMLGKPGKIPGTRELIPHESYRLVYQIDGETVWILTLVHTARLWPPVRD"
misc_feature 40820..41080
/locus_tag="Tint_3241"
/note="Plasmid stabilisation system protein; Region:
Plasmid_stabil; pfam05016"
/db_xref="CDD:203153"
gene complement(41297..41644)
/locus_tag="Tint_3242"
/db_xref="GeneID:9154025"
CDS complement(41297..41644)
/locus_tag="Tint_3242"
/inference="protein motif:PFAM:PF01638"
/note="PFAM: helix-turn-helix HxlR type;
KEGG: ccs:CCNA_01913 transcriptional regulator, MarR
family"
/codon_start=1
/transl_table=11
/product="HxlR family transcriptional regulator"
/protein_id="YP_003644892.1"
/db_xref="GI:296137651"
/db_xref="InterPro:IPR002577"
/db_xref="GeneID:9154025"
/translation="MTERKTNPCFKQCPSRKFIELIGDKWALLVMHALANGPRRNGQL
MQEIEGISQKMLTQTIRRLEMNGLVARHDFQTIPPKVEYSMTELGCSFRTVLSSLDDW
LDEHVPELLTLPG"
misc_feature complement(41342..41590)
/locus_tag="Tint_3242"
/note="Arsenical Resistance Operon Repressor and similar
prokaryotic, metal regulated homodimeric repressors. ARSR
subfamily of helix-turn-helix bacterial transcription
regulatory proteins (winged helix topology). Includes
several proteins that appear to...; Region: HTH_ARSR;
cd00090"
/db_xref="CDD:28974"
misc_feature complement(order(41345..41353,41357..41365,41369..41374,
41444..41446,41537..41539,41546..41551,41558..41563,
41570..41572,41579..41581,41585..41590))
/locus_tag="Tint_3242"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:28974"
misc_feature complement(order(41396..41404,41417..41422,41432..41434,
41450..41455,41459..41464,41471..41476,41480..41491,
41519..41527,41564..41572,41582..41587))
/locus_tag="Tint_3242"
/note="putative DNA binding site [nucleotide binding];
other site"
/db_xref="CDD:28974"
misc_feature complement(order(41372..41374,41516..41518,41525..41527))
/locus_tag="Tint_3242"
/note="putative Zn2+ binding site [ion binding]; other
site"
/db_xref="CDD:28974"
gene 41742..43856
/locus_tag="Tint_3243"
/db_xref="GeneID:9154026"
CDS 41742..43856
/locus_tag="Tint_3243"
/inference="protein motif:PFAM:PF03781"
/note="PFAM: hypothetical protein; Methyltransferase type
12;
KEGG: tmz:Tmz1t_3577 hypothetical protein"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_003644893.1"
/db_xref="GI:296137652"
/db_xref="InterPro:IPR005532"
/db_xref="InterPro:IPR013217"
/db_xref="InterPro:IPR018201"
/db_xref="GeneID:9154026"
/translation="MKSLFPRTPFLAGSDVEAKRTELLHYFHATFDRYESLFEVLSCD
EAYYKKPITLRHPLIFYFGHTATFFINKFLLAGLIDKRIDPRLESMFAIGVDEMSWDD
LDDARYEWPTVAEVRAYRNKAREVIDGVIRYTPFSLPIGWDDTFWVVLMGIEHDRIHL
ETSSVLMRQHDLKYVTPHPDWQPCRDSGTAPTNTLVNIPSGRVVLGRALTDPIYGWDN
EYGHHQADVPTFQASRYLVSNGEFLEFVTAGGYTDDSLWDEEGLGWRRYARAEFPTFW
VPSADGWKLRLLAEEVPMPWDWPVETNCLEARAFCRWKARETGQSVRLPTEDEWHRMY
DHVHLSDVPHDAPAAANLHLDHWASSCPVNRFIHGDLADVVGNVWQWCETPTYPFDGF
DVHPIYDDFTSPTFDERHNIIKGGSWIATGNESRHASRYAFRRHFFQHAGFRYVVTDT
PVPNPVSAYETDAMVSQYAEFHYGETTLGVPNFPQAMAQLAIDFHRRHGNGGKARALD
LGCATGRASFELAKTFDKVIGIDFSARFIQVGIRLAETGAIRYTMPEEGELVGYHERR
LDSLGLLETAQRVEFWQGDACNLKDIFSGFDLILAANLIDRLYAPRRFLDTVADRLNS
GGLLVLASPYTWLEEYTKRSEWIGGFKKDGESRTTLDGLKEILGRKFVMVEAPLSVPF
VIRETRRKHQHTLSEVTVWKRK"
misc_feature 41808..43073
/locus_tag="Tint_3243"
/note="TIGR03440 family protein; Region: unchr_TIGR03440"
/db_xref="CDD:163266"
misc_feature 42321..43079
/locus_tag="Tint_3243"
/note="Formylglycine-generating sulfatase enzyme; Region:
FGE-sulfatase; cl15394"
/db_xref="CDD:199530"
misc_feature 43254..>43655
/locus_tag="Tint_3243"
/note="Methyltransferase domain; Region: Methyltransf_31;
pfam13847"
/db_xref="CDD:206018"
misc_feature 43254..43631
/locus_tag="Tint_3243"
/note="S-adenosylmethionine-dependent methyltransferases
(SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
that use S-adenosyl-L-methionine (SAM or AdoMet) as a
substrate for methyltransfer, creating the product
S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
cd02440"
/db_xref="CDD:100107"
misc_feature order(43266..43286,43332..43337,43491..43499,43545..43547)
/locus_tag="Tint_3243"
/note="S-adenosylmethionine binding site [chemical
binding]; other site"
/db_xref="CDD:100107"
gene 43841..45025
/locus_tag="Tint_3244"
/db_xref="GeneID:9154027"
CDS 43841..45025
/locus_tag="Tint_3244"
/inference="protein motif:PFAM:PF03747"
/note="PFAM: ADP-ribosylation/Crystallin J1;
KEGG: tmz:Tmz1t_3570 ADP-ribosylation/crystallin J1"
/codon_start=1
/transl_table=11
/product="ADP-ribosylation/Crystallin J1"
/protein_id="YP_003644894.1"
/db_xref="GI:296137653"
/db_xref="InterPro:IPR005502"
/db_xref="GeneID:9154027"
/translation="MEAQVMPLTNPDHYRDRALGALMGAFIGDALGIGPHWYYDLDQM
VADYGPWVDSYTRPKPGRYHEGVEPGQPSQSGILLEMTLRSSVECGGYDEADFCRRLD
TELFPKLDGTPMNGPGGYTSQSIRDAWRNRVQEGLAWGSFGSDVDNTEAAERIIAIAV
RYALNPAKLAWAVTANTALTQTNSNVLTTTTTYGAVLGMLVEGHRFDADISDKLMDRI
KADKRIARFNSAVQPLHAAAQGRLEVQIHTDCQPCMETFFPSHDALVTPSGVARAAHD
SGIRIEPASKVSLLYGLPCGVHHQFPAAYYLTARFQDDFESAVLHALNGGGQNQARAM
LTGALSGAMVGLSGIPRRFIDGLERAKVLLALGERLVGDMQSQAQKNGSPGYFIDERR
CP"
misc_feature 43898..44896
/locus_tag="Tint_3244"
/note="ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH;
pfam03747"
/db_xref="CDD:202756"
gene 45022..45684
/locus_tag="Tint_3245"
/db_xref="GeneID:9154028"
CDS 45022..45684
/locus_tag="Tint_3245"
/inference="protein motif:PFAM:PF01323"
/note="PFAM: DSBA oxidoreductase;
KEGG: dar:Daro_1034 DsbA oxidoreductase"
/codon_start=1
/transl_table=11
/product="DSBA oxidoreductase"
/protein_id="YP_003644895.1"
/db_xref="GI:296137654"
/db_xref="InterPro:IPR001853"
/db_xref="InterPro:IPR012336"
/db_xref="GeneID:9154028"
/translation="MNPSQPLTIEIVSDVVCPWCFIGLRRLDLALEAVRRRHPDIRCI
KRWCPFFLNPSVSPEGEPYLPHLVKKFGGPERVQAAFQHVRDAGAAYGLDYRFEDIKV
LVNTFQAHRLIHWAQQSGDAQILVERLLIGQFQRGENLGDEAVLAKIAVECSYRETAI
VEYLNSDEDNQLVQEQERESRAWGVTAVPTFIVGRKLMLAGAEDPMLFAEAIERVLVM
GS"
misc_feature 45028..45669
/locus_tag="Tint_3245"
/note="Predicted dithiol-disulfide isomerase involved in
polyketide biosynthesis [Secondary metabolites
biosynthesis, transport, and catabolism]; Region: FrnE;
COG2761"
/db_xref="CDD:32627"
misc_feature 45046..45660
/locus_tag="Tint_3245"
/note="DsbA family, FrnE subfamily; FrnE is a DsbA-like
protein containing a CXXC motif. It is presumed to be a
thiol oxidoreductase involved in polyketide biosynthesis,
specifically in the production of the aromatic antibiotics
frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024"
/db_xref="CDD:48573"
misc_feature order(45070..45072,45079..45081)
/locus_tag="Tint_3245"
/note="catalytic residues [active]"
/db_xref="CDD:48573"
ORIGIN
1 atttgaacgt gaacgcccgg ctgccattgc cgtgatcgaa atggcggctg gtgacacgac
61 tgcttgatct acccccgttt tgtggttcag acatgcgctt atcctttcgg atctgaattg
121 gatagcgtaa ccttactccc gtagctatgt acggactcaa gcgatatgga aaacaatttg
181 gagaatctga ccatcggcgt tttcgccaag gcagccgggg tcaacgtgga gaccatccgg
241 ttctatcagc gcaggggctt attgccggag ccggacaagc cctatggcag catccgccgc
301 tatggcgagg tggatgtaac acgggtgcgc tttgtgaaat cagcccagcg gctgggcttc
361 agcctagacg agattgccga gttgctgcgg ctggaggatg gtacccattg cgaggaagcc
421 agcagtctgg ccgagcacaa gctccaggac gtgcgcgaaa agatggccga cctggcgcgc
481 atggaggccg tgctgtccgg gcttgtgtgt gcctgtcacg cccggaaggg gaatgtttcc
541 tgcccgctga ttgcgtcatt gcaagacgga acgaacctca ccgtatcggt gcggggtgat
601 cacgggttga ctacgcctta gcgtgcttta ttttccgttt tctgagacga cccctcccgc
661 gtccgtgctg ccgggcttgc gcttttcaat atcgtagcgt atcatatcaa tcatatcgta
721 ccgtatcata tcggaaagga gccgcagcat gggacgcgaa gccaccatca cccccgagca
781 ggtccacgcg gtcgccgacg ccatcaaggc cgaaggcagc aaacccacgc tgcgcgccgt
841 gcgcgagcgg ctggggcagg gcagcatggg caccatcgcc aagctgttgc agcagtggaa
901 ggtcggccag gaacgccagg ccgctgccga gctggtctta cccccggcct tgcagcgcgc
961 ggtcctggac ttcatggccg ccgagctgtc ggccacccgc gccccgctcg aagccgaact
1021 ggccgagcag cagcagaccg ccgccgacct tgccgcggag aacgagcgcc aggccgacac
1081 catcaccgag caaggcgaag ccctggacgc cctggcggcc gagaaggccg ccgccgaggg
1141 caaggccggg caactggccg ccgacctgat tggtgcgaag gaagaagccg ggcacgagcg
1201 ccaggccgcc gaggcggccc gcaccgagct ggcgaaggcc acccttcgcc ttgaggccat
1261 gccccggctg gaagccgagc tggcgaaaga gcgccaaggg cgcatcgagg ccgagcagca
1321 ggcggccgtg ctgaccgcgc agaaagccga cctggaaggc cggctggtgg acgccaagaa
1381 ggaagcagag cgcaccgccg cgcagttgca gcgggcgcag gaacgcgccg agcagcaggc
1441 cgaggccctg gccgacgccc gcgtgacgat ccagaccgcg caggcccgcg ccgaggacct
1501 ggccggccag gtggagcagg cccgcaagga tgccaaggcc gccggcgagg aagccgcgat
1561 cctgcgcggt cagatcgcag cgcagggcga gcggccggcg agcgccacgg ccccgaaaag
1621 caaaacgccc aaggcatgag ttgcttagct tgatgtaact acaaaacgag actacaataa
1681 agccgcgatg gaacttgaat gggacgccga caaagcggca cgaaacatgg aaaagcacgg
1741 cgtttccttc gaggatgccg ggcttgtttt ttacgacgct gggcggattg aggcctacga
1801 cggacgcgag gactacgggg aagatcgatg ggccacgatt gggcttgctt actcggctgt
1861 cctgtatgtg gtctacaccg ttcgacacga ggacgccatc cgtcttctct ctgcgaggaa
1921 agccaatgcc gacgaaagaa agcaatatcg tgaagcgaac tcttgacctg aaaaagccgc
1981 ccgtcttgag cgccgagcag aaggcccggc tagatgctgt ggcttcgatg ccggatgagc
2041 agatcgacta cagcgacgcg ccgagcctgc ctgctgctgt ctggctgaag gcagcagcgg
2101 agttgcccca catcaagcag caaatcacgc tgcgcattga tgctgaagtg ctggaatttt
2161 tcaagcacac gggcaagcgg tatcagtccc gtatcaatgc cgtgttgcgc tcctacgttg
2221 acgcgcacaa ggcgcacgcg aaatgaacga cggggcttga cgggcaccgg gccgatcaat
2281 accccctcgg aatcaccagc gcgactttgc cgccattggt ggtccagcca ccgagcgggg
2341 tcggattgcc gctgctgtcc tggccttggt tgccgctgac ctcgaagcac agtcgcccgt
2401 cgcacgtcga ccaccgcacg cggccgccgc gcttgtccag tgcggccaca gtggcctgct
2461 cctgcgcgat ggtggcctgt agctgcacct gctgggccag caggccgctg acctcgtgcc
2521 gttcccagcc gaccaagccc cacgcggcca ggccgacgat caaggtcagg gccagagcca
2581 ggaccacggc ctttgcgcca aaccaccggc cagcggcggc catgcgggcg ttggccgcct
2641 cgaccgtccg cgtcaacgac tgctgcgccc tgttcaacgg atcgacctgg cgcgcgatga
2701 tgtccgccgc cgtggcttga agcgtgcgcg tgagctgttc cgtcagctgc gcggtcatct
2761 tcaccgcttg cgcttccagg ctttgccgac cgtccgccgc cgttttccgc agccccgcgc
2821 cgatctcggc cgccgccttc tcgacctcgg acagctccgc atccttggcg gcatggatgg
2881 ccttcatggc ctggcggatt gcgtgatccg acccttcctt gaccgccgcg cccagatcct
2941 cgatggcgtg ctggattgcc agcaggccgt gctggctgat ggcgaacgga atccactcgg
3001 gcgattcgaa atcgaggccg taggccgccg ccgccgcata gatcgctttc ttgtcctcgt
3061 cgggcagctg gcccatgagt ttgtcgaatg cctgcttgct catttccccg ctcccaggcc
3121 gatcttgtcc gcgaccttat ccagctgcgc atcggtatcc ttcatccacc ggatgaggcg
3181 cgaccgctgc gcccgcgaca acggcgaacc atcggccgcc gcatcggcga agcgcatcat
3241 gcggtcatca atggcgacca tgacgccggc ctgcagcttc ggcaggtcga tttcctcgcc
3301 gccgtagtcc ggcagcatgg cgcggccccg gctgggcggg ttgccgttgc cgtcaccgaa
3361 ccacatgtag aaatcctcat cgtcgccgaa ccagcgattc acgaccgcga cgtaatcggc
3421 gctcttgccc gccagatcga ccatttgctg caccgtgcgc gtgctcgact ggaagggcga
3481 cagaacattg accatcgtcg gcctgtagcc cgaccgctgc agctcatcga agaagcctac
3541 ttcggcgtcg aatttcgcca gcgccgtgat cgacgccgcc ggcatatcga ccaggaccac
3601 cggcaggtca tagtccagca tcgccagcag cttgtcgcgc tctttttcct cgcccgtgac
3661 gcgcatcgtc atgacgccat caccggcatt ttgcgtggcc ggattgccgt cctcatccag
3721 cttgcaatag tgctggtaaa gctgacccac ttcgccatct ccatcgacca gaagcgcctt
3781 gatgccatcg cgcgcatacc tgtccgcaat ggcccgcgtc atcgttgact tgccggtgcc
3841 gcccttgtcc gtcagtacca tcacaaatcg tttcatcgca taccacgctt gcttgccgct
3901 ggtgtcagcg tagtttccgt ctcatcgcgc agcacctgcc gttcctctgg cgtgaccgtt
3961 cgccgcgctt gcggcgcggc actgtttccg ccttcatact cgaccttttt tgcggccttt
4021 gctggtcgct tcttggtcga ttgccgcata gcggccttga gcgtcgttag tccgatgtcc
4081 acgccgcctt gtttgaacga ctgcacgatt tcttcaatcg tgtagccctt ctcttgcgcg
4141 gttctaatct cggccttcag cgatgtgatg atgtctttcg cagccagtcc cttgtccgcc
4201 ttcggcttct ccgggagact ggcgatgatc gatgccacat cgtcacgtgc tttcattgtg
4261 aatgtctttg gttttcctgc cattatgttt gtcctcatga ttgacgtgat gccgacctta
4321 cggcaccgag tgcaactgta tgccccggtt ttgcccttgt caataatcgc cgcacgtggt
4381 aaacatgtat gaactgcctg tgatagttga gtatgggaca gggtagggga tgtaataccg
4441 ccgctgacgc gacagtattc caccggcccg cgccactcgt tgcactcgtt atgctggcct
4501 tccctccctg ctcagggctt cgccccgaga ccccaacccc gcgctgccac cggcagcgcc
4561 tggccttcgg ccccaagtga aatccgaaca gaggaccgcc gcagatgagc aacagcgaca
4621 gccgcaagcg caccctggcg cttgccgtgc gcgtcacgcc agaagaggcg gacgccatca
4681 tggagaaggc gcgcgacgcg ggcgcaaccg tgtccgagtt cctgcgcgcc tgcgcgctcg
4741 gacgcaagac acgcaacacc gtcgatagtc aggtcatcaa cgagctgcgc cggctcggcg
4801 gcctgcagaa acacctgttc cttgagggcg gcggcgcgaa ctcctacgag cacgccgcca
4861 tcctcatcga gatcaagaag gccgtggcga ggattgcgac gtgatcccca aggtcgtgcc
4921 gcaccgtggc gacggtaata gcagctggcg gcaggccgtc gaatacgtca gccggcactc
4981 gcccgagcgc gaggccgagc tagaccgcga ggcgggcgac atcgaccgca ccgccgccga
5041 gctggcgcgc gacatcgagc tggccggccg ctacgacgac gaggcggcgc tatcgcaccc
5101 gagccgcgac gccaccctgc gtgcggccta cgatgccgag ctgtccgccg atggtccgcc
5161 gccgtccaag gcgcgcacct tgagccaagc acccaccctt gggcgcgtgg gcgtgcttcg
5221 cttggaagga caggaagagg aacacgccaa ggtcaaggat gaggccgaat atgggcgcga
5281 tccgtcgcgg cctacgatgt tcacgaactg cctttccgtg cgcacggcgc acgcggaaat
5341 gaaggcggta tcagacatgt gcagccgggc gaaagacccg gtttatcaca cgctgctgtc
5401 ctggcggccg ggcgagcggc cgagcgatgc gcagatgttc gaggccggcc atgcctcgat
5461 gaaggccgta gggatggagg ggcaccagta cgttttcgcg gtccaccgcg acaccggaaa
5521 cgaccacttg cacatgctca tcaaccgggt gaatcccgag acgtacaagg ccgtctatcc
5581 gtcgcgcgac ttctacaagc tcgaccgtgt ttgccgcgag gtcgaactcg cccagggctg
5641 ggagcacgac aagggccagt atgcggtcat cgaccgcgac ggccagaagg ccatcgttcg
5701 ggcgagcaag gaaacccgga tgcaggagaa gcgcccgacc aaggcgcgcg acatggagga
5761 agtcggcggt caggaaagcc tgttcagcta tgcgcgaggc gagccgcgcc aggccgtcgc
5821 ggcgctgctg aaagacccgc gcaccagctg gcaggacctg cacggcgagc ttgccaagca
5881 tgggcttgag ctgcgcgaga agggccaggg cctggcgatc tacgacaaga cccacccgga
5941 gcgcacgccg atcaaggcga gcgacatgca cgaggggctg ggccgtggca agctggtcaa
6001 gcggctgggc gagtaccagc cgccgatccg tgccattcag atcgagcagc cggcccgcag
6061 ctacgacaag caccgagaac cggcgcgcga tccgagccgg cgcgaccagg cgcgggagga
6121 acgcgcgcag gctagagcgc gcctgcggca gcagtacgac gaatggctgt ccgagcagac
6181 caaggcccgg cagcagagcc gcgcggcctt gcgcaccggc gaccgagcgc gcttcaccga
6241 cctggccgcg caccacaagg cgcggcgcga gcaaatccgg cgaaccgaca tgcccgcgcc
6301 gatgcgcaag gcgctgtaca gcgtggccgc gatggaggcc ctgcaggcgc gcgagcagct
6361 gcgcgccgag ctggacgaca agaggaaggc cgagcgggcc gaccggccgc agaatttccg
6421 cgagtggacg ggcgaccgcg cccaggaagg cgaccaggcc gccatcagcc agctgcgcgg
6481 ctgggcctac gccgaccgac gccgcgcgaa ggagctggaa aaggccgagc aggagaacgc
6541 caagaaggac ggcatcacca tcgaggcccc ggccggccgg caggagccgc tatcgccgcg
6601 ccgcctggcg atgctcgacc agctgggcta ccaggtggat cgccggacgg gcgacgtgca
6661 ttaccaggcc aaggaacggc acgtgttcac cgactcgggg cggcgcatca cgttcagcgc
6721 cgccggcgcc accgaccgcg aggccctggc cgccgggctg gccctggcgc ggcagaagtt
6781 cggccagacc ctcacactga ccggcagcga gcaattcaag gatgaggcca tccgcgtcac
6841 ggttgaaaag cgtctggacg tgcgcctggc cgatccggca ctggaagctc gaaggaaggt
6901 cctggaagcc gcccgcgacg ttgccaagcc ccaccccagg gagcgtgccc aggaacgcaa
6961 ccaagtcccg gacaagggcc gcggcgggca ggagcgatag ccgcggatta ccgcttcagc
7021 aaggtaacaa gctgctgcac gttgaggccg ccgccgacca agctcgcgcg cattggctcg
7081 aaggccgtaa tcatgcggcg atagcgtccc tcggtctggc agtgcgagtt caaatcgcgt
7141 cctttgaatc ggctgaaccg acccatcttg ttgaccagga agccggcgat gctcatctgg
7201 ccgcattcgt tattgccatc aaacccgtgg aatttcacat cggtggccca ctcgtccacc
7261 tcggccgcga tggccgcttt ctgctcagaa ttaagtcgtt cgtaggcctc ctcgatgaag
7321 gaccacatgt cgagaacgtc aacgacatag gacacgtctc gcgggttgtc tacgtggtcg
7381 tggaagaccc cttgcatatc ccatttcggt gcccagtagt ggcctccgta gatgacttga
7441 gctaggaagt cggggttcga ctccgggtcc ttgatcttca gtgctttgaa taggtcgccc
7501 atcatcaata tgagcatctt ttccccgtcg ctgaagtgca cggcgcggct cgaaccagcc
7561 gacaggccca ggttgactag cctgcgcaca gcttccgctc gcgttggctg gtccggttgc
7621 tcgctcgccc actcatcaac ccgcgcaagt tgctcttcgt cgatccgaag ctcaaagcgt
7681 tccgattttg ctgccatacc gtacctcttt cagttatgta cgtacacatg tccgatattg
7741 tacgtcatac atacgtactg caacaagtcg atccgtaagc gcgagctgtg tccaggaaac
7801 ggtcatttct tgggcagctc tgcgagctgc cctttttgtc attttcagaa gacgaatgca
7861 ccagttaatt aggtgtggcg gctgttgtgc ggccagctcc tgacagtcca atatcagaag
7921 tgatctgcac caatctcgac tatgctcaat actcgtgtgc accaaagcga ggtgagcatg
7981 gcgaccgaca ccccacggat tcccgagcaa ggcgtggcca ctctgcctga tgaggcttgg
8041 gagcgtgcgc gccgtcgtgc ggagatcatc ggcccgttgg cgcagtcgga gacggtcggg
8101 cacgaagcgg ccgatacggc ggctcaggcg ctgggcttat ctcggcggca ggtgtacgtt
8161 ctgatccggc gtgcccggca aggcagcggc ctcgtgacgg atctggtgcc cggccagtcc
8221 ggtggcggga aaggcaaggg gcgcttgccg gaaccggtcg agcgcatcat ccgcgagcta
8281 ctgcaaaggc ggttcctgac caagcagaag cgcagcctgg cggcctttca ccgcgaagtc
8341 actcaggtgt gcaaggctca aaaactgcga gtgccggcgc gcaataccgt ggccttacgg
8401 atcgctagcc ttgacccgcg caaggtcatt cgccggcggg aaggccagga tgccgctcgt
8461 gacctacaag gtgttggcgg cgagcctcct gccgtgaccg cgccgctgga gcaggtacag
8521 atcgaccata cggtcatcga cctgatcgtg gtcgatgagc gcgaccggca accgattggc
8581 cgcccgtacc tgaccctcgc catcgacgtg ttcacccgct gcgtgctcgg catggtcgtc
8641 acgctggaag caccgtctgc cgtttcggtt ggcctgtgcc tcgtgcatgt cgcctgcgac
8701 aagcgtcctt ggctggaagg gctgaaggtg gaaatggatt ggccgatgag cggcaagccc
8761 ttgctgctct acctggacaa cgcggccgag ttcaagagcg aggccctgcg ccggggttgc
8821 gagcagcatg gcatccggct ggactatcgt ccgctgggac agccgcacta tggcggcatc
8881 gtggaacgga tcatcggcac ggcgatgcag atgatccacg acgatctacc gggaacaacc
8941 ttctccaacc cggaccagcg cggcgactac gattccgaaa acaaggctgc cctgacgctg
9001 cgcgagctgg agcgctggct cacattggcg gtaggcacct accacggttc ggtgcacaac
9061 ggcctgcttc aaccaccggc ggcgcggtgg gccgaggccg tggcgcgtgt cggcgtgccg
9121 gccgtcgtca cccgcgccac ggcgttcctg gttgatttcc tgcccatcct ccgtcgtacg
9181 ctgacccgca ccggcttcgt catcgaccac atccactact acgccgatgc gctcaagccg
9241 tggatagctc ggcgcgaccg cctgcctgcg ttcctgatcc ggcgcgaccc gcgcgacatc
9301 agccgtatct gggtgttgga accggaaggg cagcactacc tggaaatccc ctaccgcacc
9361 ttgtcgcacc cggcggtcac gctgtgggaa caacgacaag ctctggcgaa attgcgtcag
9421 caagggcgcg agcaagtgga tgaatcggcg ctgttccgca tgatcggcca gatgcgcgag
9481 atcgtgactg ccgcgcagaa ggccacgcgc aaggcgcggc gcgacacgga tcgacgccag
9541 catctcaagg cgtcggttcc gccgaacaag ccgacgccgc cggaaactga tgtttccgac
9601 ccgcaggcag acaagcagcc tccggcaaaa cctttcgacc agattgagga gtggtagccg
9661 tggacgaata tcccatcatc gacctgtcgc acctcttaca ggcggcgcag ggattggccc
9721 ggctgccggc ggacgagcgc atccaacgcc ttcgcgccga ccgctggatc ggctatcccc
9781 gtgcggtcga ggctctgaac cggctggaaa ccttgtatgc gtggccgaac aaacaacgca
9841 tgcccaacct gctgctggtt ggcccgacca acaacggcaa gtcgatgatc gtcgagaaat
9901 tccggcgcac gcatccggcc agtgccgacg ccgaccagga gcacatcccg gtgctggtcg
9961 tgcagatgcc atccgagccg tcggtgatcc gcttctacgt cgcgctgctc gctgcgatgg
10021 gcgcgccctt gcgcccacgc ccacggttgc cggaaatgga gcaattggca ttggccttgt
10081 tacgtaaggt cggtgtgcgt atgttggtga tcgacgaact acacaacgtc ttggccggta
10141 acagcgtcaa ccgccgggaa ttcctcaatc tactgcgctt cctcggcaac gagctacgca
10201 tccccctggt cggagtcggc acgcgcgacg cctacctggc catccgctcg gatgaccaat
10261 tggaaaatcg gttcgagccg atgatgctgc cggtgtggga ggccaacgat gattgctgct
10321 cgctgctggc cagcttcacg gcttcgctcc cgctgcgccg cccctcgtcg attgccacgc
10381 tagacatggc tcgctacctg ctcacacgct gcgagggcac catcggcgaa ctggcgcacc
10441 tgttgatggc ggcggctgtc gctgccgtgg aaagcggtga ggaagcaatc aaccaccgca
10501 cgctcagcat ggccgactac accggcccaa gcgagcggcg acgacagttc gagcgggaac
10561 tgatgtgaag ccagcgccgc gctggccgct gcatccggct cccagagaag gcgaagcctt
10621 gtcttcgtgg ctcaaccgcg tggccctttg ctatcacatg gaagtgtccg agctgctgga
10681 gcacgatctt ggtcacggcc aggctgatga catggatacc gcgccaccac agtcgctgct
10741 gacaatgctc tcccggcgga gcggcatcga gctggatcgg ctgcgttgca tgagtttcgc
10801 cggctgggtg ccttggttac tggacagcct tgatgatcag attcctgacg ctttagaaac
10861 ctatacgttc cagctctcgg tgttgctgcc gaaactccgc cgtaggacgc gatctatcac
10921 gagctggcgc gcctggctgc ccagccagcc attacatcgc gcctgtccac tctgcctgaa
10981 caatccggca aaccaagccg tattgcttgc gtggaagctg cccctgatgc tgagctgccc
11041 gctgcatggg tgctggctgg aatcgtattg gggcgtgcct gggcggtttc tcggctggga
11101 aaacgccgac gccgacccac gcacggccag cgacgcgatt gcgacgatgg accggcgtac
11161 ctggcaggca ctgacgaccg gccatgttga gctgccgcgc cgacgcatcc acgccggatt
11221 gtggtttcgg ctgctacgca cgctgcttga tgagctgaac accccgcttt cggcgtgcgg
11281 aacctacgcg gggtatctcc gcctgatctg ggaacgctgt gggtatccgc tgcgtgctgg
11341 gcaaagtctg tggcgaccgt atgaaaccct gaacctagca gtagggttgc agatgctgga
11401 ggctgcggca acggcaatca gcttgatcga ggtgagggat ataagcccgc ctggcgagca
11461 tgcaaagcta ttctggtccg agccccaaac cgagttcacc agtggcctgc cggcgaaagc
11521 gccgaagccc gaacccgtca atcactggca acgtgcagtc caggccatcg atgaagccat
11581 cattgaagcg cggcacaacc ccgagacggc acgctcgctg ttcgcgttgg cttcctatgg
11641 tcggcgcgac ccagcttccc tggaacggtt gcgagccacc ttcgtgaagg aaggcatccc
11701 gccggaattt ctgtcacatt acgagcctga tggacccttt gcatgtctta gacagaatga
11761 cgggttaagt gacaactttt gacggcctga gctttccggc gcacactgtc acataatcga
11821 acgtatatgt gacaggtatg acatgctgat cggctacatg cgggtatcga aggcggatgg
11881 ctcccaggcc actgacttgc agcgcgacgc gctgatcgct gccgccatcg atccggcgca
11941 tctttacgaa gaccaggcat ccggcaagcg cgaggatcgt cccggcttgg cgagctgttt
12001 gaaggcgttg cgttcagggg ataccttggt cgtatggaag ctcgaccggc tcgggcgcga
12061 cctgcgccat ctgatcaata ccgtgcacga tctgaccggg cgcggcgttg gcctcaaggt
12121 tctgaccggc cacggagccg ccatcgacac gacgaccgct gctggcaagc tggttttcgg
12181 catcttcgcc gcactggccg aattcgagcg cgagctgatc gcagagcgca cagtagcggg
12241 cttggcctcg gcgcgggcgc gcggcaggaa aggcggtcgg cctttcaaaa tgacggccgc
12301 caagctgcgc ctggcgatgg cggcaatggg gcagactgaa accaatgtcg gcgacctgtg
12361 ccaagagctc ggtatcacgc gacagacctt gtaccggcat atttctccca aaggggaatt
12421 gcgcgcggat ggaatacgac tgctgtccaa ggtgtaaaag aaaaactggc ctctacatgg
12481 tcagcacgga ttcgaggatg aaggcgctca tcgcggcatc aattcaccta ttcacgccgt
12541 caaatcagct tttttgtact gccatttgac gcgatgaccg caaattgatt gtaaaggcca
12601 ccacaacgat gaataacaca gcgaattgcg ctgagagtgt ttgccacgac ggatagatgc
12661 ccagcagatc aatgcgtggg atcgatattg ggctggtatg caataaccct gcttcttgca
12721 gacctgcgat gcccttgcct gccaagacca cggcaagtat ggccaccagc agtgagctgg
12781 cagcgaagaa ctggccaatc ggcaggcgcg cactggtgcg cagcagtatg actgccagca
12841 gggccaggat tcccatgcca gtgcccaagc ccgccagcag gggccagcca tttccttctg
12901 tccagagcgc tgcgtagaac agcaccgtct cgaacacctc acggtagacg gcgacgaagg
12961 ccagcgaaaa caagaaccat gccgtgcgct tgttcagcgc cgacgacagc ttttccttga
13021 ggtagacctg ccaacgaccg gcaacgctct tctggtgcat ccacatgccc acacccagca
13081 agaccacggc ggcaaagagt gacgaaaagc cttccgttag ctcccggctt gccccactga
13141 cgccgaccaa gtaagttgcc actgcccatg taatgccgcc tgcggccagc gcggatgccc
13201 agcctgcatg cacgtagatc aatacgtctt tccgttcggc tttcttgaga aacgccagca
13261 tggcaacgac caccagcagg gcttccaatc cttcacgtag caagatggtt aacgcaccga
13321 tgaaggccgc cacggcatcg tcgtcggagg gagcaagcac cttgtccgct tcatccagca
13381 agccgcgcaa atgcagctcc gctgtctgca catcggcagg cgaaccattg gctatcaatg
13441 cccggtagga caccatcgcg gcttcgatct tctcgaacag cggccgattg cgagtggcca
13501 acgccggttc gaccggctcg aagccatcga ggtaagcaga caaggctagc ttggtcgcac
13561 ctgcacggtc gtcagccagc aatgccgtca cgctctcact gagtttggct ttggcaatcg
13621 cggtgccctt cggactgctg atattcagcg cgctcggatt ggcgcgcaaa taggccgtca
13681 gggctctggc ggaaggctca tccagcctgt ccgccaagac atgctcagat gtttgcgtca
13741 gcacatccag actgacgagc gtctggcgaa cctgcgcgtt ggcttgccag agcttggctc
13801 cttcgtcctt gtcgctttgc gtataaggta gcgtgccaac aaagaacgcc aatgcccatc
13861 ggtcttcatc cgacaacgcg ccaaagccct gcatagcggt gccctggaca ccgttgctga
13921 taatttggtg tagcgcgaat aagctgcgct cgcgcgcccg catgtgatcg gccagcgcgg
13981 tcggcttggg gttgagggat gccgctaggg ggccatcacc gcgcccttgc tgaccgtgac
14041 aggccgcaca ctgggcctga aacaactgcc ctcccttcgc taagaccggc atggcagtcg
14101 gtgcgactgg aaacgggtac gccttttgca ccgcactgga cagcgcgtgc gccagttttg
14161 ctacgctggc cggatcggct ttggcagcta ccgcagcacg caaagcggtc gcttgttgca
14221 acaagcgacc cttgtcggtc tggtcaggta attctcccag ttgacgttcg gctgtcgctg
14281 aaaattcctg catttcagcg tactccgacg atttcaggac cacaccgttg gctaccgcgc
14341 cgccgtaatc gacggcgacg tagtccagaa gttgccaaat ctgtttggct ttgagttcgg
14401 tggtgttggc tgcgtagctt ggcccgccga ttaacgagca aatcgccaac agcaaagcca
14461 tcagccagcg atagggtaat cggcagggca tgggaattct ctggttaaat cattgagaat
14521 gattataatt cgcaattgat cctgtgtcca tcctcttttc ccgggtctgc atctgcatga
14581 tgagcaaagc agcgcccgac gtgatcgcca cgtcagcgag gttgaaggcg ggccagtgcg
14641 cgagccgcca atggaagtcg aggaaatcaa ccacctgtcc acgcaacatg cgatccgcca
14701 cattgccgag cgcaccacca aggatcaggc tgtagcccat cgcttcgaga cgtggccgtt
14761 gctggcacag catgcgaccc agccaagcag aaacaaccag acccaacgtg atgaaaaagt
14821 aacgttgcca gccgccagcg ttcgccaaaa agctgaacgc cgcacccgga ttcaggacgt
14881 gaacgaggtt gaaaaacgga gtgatttcga cttgctcacc gtaggcaaac gtgcgaatga
14941 tggcgaactt ggtaagctga tctgtcatga caatagtggc ggccacggtg aaccagatcc
15001 aggccgacgt gcgacgagcc gattgccata cagaggcggc cagcggaagc agccaccggg
15061 cgagtgccgt gcagctccat cccagcgccc accccgccaa cacatccgcc gggaagtgca
15121 ttcccgcagc gatgcgcgac cagccgacca acgtggcata tagcaccaag ccgacgcgac
15181 catggcggcc catcaacggc cagagtgcac cgaccaccag cgcggcatag gtggcatgcc
15241 cgctgggcag gctgtagtga agctctttgt ccccgatgac gcgcaccagc tcgccaagga
15301 cggcaggcgg gcgtggaaag tcgaaccata gcttcaagac ggtggcgacc aataacgcca
15361 gcaagaaggc cgcgctaaaa ccaataaggc gatgccgaac ggccgtgcca cgcgccgcgt
15421 tagtagccga tttcgaccac caccacagac ccaacagcat cagcggcgct gtccagtaac
15481 ttcccacgag gctaaagaac catgccagtg gttccagcgt ggcgggcgtg cctgtgttaa
15541 tgacttgaaa caacgcgatg ttcaggccac cccagtcata gagaaagagt ttccagctca
15601 tcgacgcaac agcctcaagc cgttgccgac aacaagcaag ctggcaccca tatcggcgaa
15661 cacagccatc cacatggtcg cgtgacccgt gaaagtgagc accagaaata ccgccttgat
15721 gccaagggcc agcacaatgt tttgcatcag cacctgtgct gtcgcacgcg acagacgcac
15781 gaaggtcgga atcttgcgca ggtcatcgtc catcagggcc acgtcggcgg tttcaatggc
15841 ggtatctgtg cctgccgctc ccattgcaaa gccaatgtcc gcacgcgcca aggccggtgc
15901 gtcgttgatg ccatcaccga ccatgccaac cttgccattt ctggacaatt gctccacttc
15961 gcgcagtttg tcgtcaggca gttggttgcc ttgcgcacgg tcaatgccag cttgtgcggc
16021 aatggcctgg gccgtgtggg ggttatcgcc ggtcagcatc acggtgttga tgcccagagc
16081 atgcagctcg gcgatggctc tcctgctgct gtccttgatg gtgtccgcaa cggcgaataa
16141 ggcatgtacc ccttttgcgc ctaccaacat cacgacggtc ttgcctacgg tttccagcgc
16201 cgcgatgcgc tgctccagct ctggtgtgca ctgccccagc tcttcaagca ttcggtggtt
16261 gcccagatag taggtctccc cgtcgatttg gccttgcaca ccccgaccgg gcagcgcgtt
16321 gaattcggcc acgtcgagca aggcaacccc gtccgtctgc gcggcctgtg ccaccgcttt
16381 ggatacagga tggtcggagc gggctgccag actggccgcg atgctgcggc tgtccgaggc
16441 gagtgcattg ccccaggtga caaaatcggt ctgtgcgggc ttgccgtgcg tgatcgtgcc
16501 ggtcttgtcc agagccagcc aacgcagctt gcggccttct tccagataga cgccgccctt
16561 gatgaggatg ccgtggcggg cggcggcggc caagccgctg acgatactga ccggcgtaga
16621 gatcaccagc gcgcagggac aggcgaccac cagcagaacc aatgcacggt agatccagtc
16681 gagccatgcc gcacccatga acagcggcgg caacaacgcg acggcgatgg ctagggcgaa
16741 cacgatgggt gtgtaccagc gggcgaactg atcgacaaaa cgctgagtcg gcgcacggct
16801 cccctgagca gcctctacgg cgtgaatgat gcgggccagt gtggagttgc tggccacggc
16861 ggtgacgcga tactcgaatg acccggattc gttgatggtg cctgcgaaca ccgggtcacc
16921 gggggatttt tcgaccggga ggctttcgcc cgtgatcggg gcttggttga ctgtagaacg
16981 gccttcaagc acctcaccat cgagcgcgat gcgctcaccc ggtttgaccc ggacgcggct
17041 gccaatggcg atttgctttg cgctcacctc gcgccatgtg ccgtcagcct gttgcactgt
17101 ggcctgttcc ggggtcatgt cgagcaggcc acggattgcg ttgcgagcgc gatccagcga
17161 cttggcttcg atcacttcgg ccagcgcgaa gagcaccatc accatcgccg cttcgggcca
17221 gtgaccgatc aacatggcac ccgtgacggc aatcgacatc agggcgttca tgttgagatt
17281 aaggttcttg agcgcgatcc aacccttttt gtaggtggag aggccacctg tgaagaccga
17341 aacgagcgcc agaacgacaa ccgaccaatg attgccgttg tggagccagt agaccgcctc
17401 ggctgccaat gcagtgagca aggagatgcc tagcggccac cagttggtcg gcgtgatcac
17461 gggggaagcg gatggcgatg cggactctgc ggtgtccatc acctgcgcct caaatccaag
17521 cgcttgcaat gccgcgagca cgttgggcag aacctgatcg gcatgacgca ccgacagcgt
17581 gcgttgcatc aggttgaaat cgagatcggc aaccccggcg actgtgccga gcttgttgcg
17641 gatcaacgcc tcttcggtcg ggcaatccat cttggcaatg gacagcttgg tcgttttttc
17701 ggtcgatgcc tgatccatgc gcacggcttg catgccgatg gcggctagcg cctgctcaac
17761 gggtgacagc gaaggcagtt cgtgccgaac ggccaaagta cgctgcatca ggttgaactc
17821 aagaccaacc acacccgcca gcccagccag cttgcctcgg atcagcgcct cttccgtggg
17881 gcaatccatg ttctcgatgc ggtacaccgc ttgagccgat ccggttgcca gcggggcttg
17941 tgccgtgggt tggatgattg gcccagtcga gcagccacac ccctttgaag cgcattcgct
18001 catggataac tccttcaaat cgtctattca gcctccatta aaaactctat agtcgctata
18061 gagtcaagtg aaaaatggag attgaggcat ggaaatcaga attggcgacc tcgccaagcg
18121 ctctgggtgc gaggtcgtga ccatccgcta ctacgaaaag gaagggctgc tgccgaagcc
18181 agcgcgaagt ggtggcaact ttcggttgta cagcgatgtg cacatcgagc gtttgcagtt
18241 cattcgtcat tgccgttcgc ttgacatgac gctgagcgaa atcaggatac tgctgggcct
18301 acgagataac cctgctcagg actgcggcga cgtcaatgca ctactggatg tccatattcg
18361 tcagaccgaa gagcgcgtgg aagcgctgtt gcaattgaag cggcacttgc tctcgctgcg
18421 tgaaaaatgc tcgggcgctc gacgaataga ggcatgtggc atcttgcaag gtttatcaga
18481 ttgcgatcat ccgggatgca acgcatagca tgaagtgtct cgcacgccga cattggcctg
18541 cgattttggg ctcgtgagcg gcctgcctaa ttggcatcgg agaaggtcgt gcggctgact
18601 tctgatattc cgtgctgtcg tcttctgaaa atgacaggtt ttgcctgtcc aaactgccgc
18661 ccggctgtta aaattgacgt caacttatca acgtccagca aacacacctt tgctggacat
18721 ttttgtgtca ggaaggcggg tatcggccaa tggggcagcg catcgggtac gcccgagtct
18781 cgacagatga ccagaacctt gatttgcagc acgacgcgct gcgcaaggct ggcattgccg
18841 atgaccgcct ctactccgac accgcgagcg gcaaggacgc cgaccgcaag gagctgctgg
18901 cttgcctcaa ggcgctgcgc gagggcgaca cccttgtggt gtggcggctg gatcgccttg
18961 gccgcagtct gccagacctc gtgcgcatcg tcggcgagct ggagcatagg ggcgtcagct
19021 tcgagagcct gactgaaccg ccccgacttt cgtggaggcc agttggttta agtcaggcca
19081 cagtggtgac gtgactggct tgctgcctcc agtagtttgc ctcagcttct gccggaggga
19141 tatagcccag gggttccatc aagcgatgat ggttgaacca ggccacccat tccagggtcg
19201 ccagctcgac ggattccttg gttttccagg gggcacgacg gtgaatcaat tccgccttgt
19261 acagcccgtt gatcgtctcc gccagcgcgt tgtcatagga gtcgcctttg ctgcccacag
19321 aaggttcaat tccagcttca gccagccgct cggtgtagcg aatgctgaca tactgcgatc
19381 ctctgtctga gtgatggatc aaggtctcgt tctgttcggg ttggcgggca tagagcgcct
19441 gctccaaggc atcgagcacg aagtccgtgc gcatggagct gcttacccgc cagccgacga
19501 tgcgccgggc aaacacatcg atgacgaagg ccacatacag ccaaccttgc caggtggaca
19561 cataggtgaa atcagacacc cagagctgat tgggccgctc ggccttgaag acccggttga
19621 catgatccaa cgggcacggc gccttggcat cggcgatggt ggtgcgcacc accttgccgc
19681 ggatggcgcc gcgcaagccc aggcgccgca tgagtcgctc caccgtgcag cgcgccaccg
19741 ccacaccctc gcggttcatc tgcttgtaga ccttatccac gccatagacc tgcaggttcg
19801 cttgccagac ctgttggacg tgggggatca gccgctgatc gcgctgggcg cgtggtgaca
19861 gcaacgccgg gttgcgctgc cgggctgcgt gcaggcggta tccgcttggg gcgatctgca
19921 gaactttgca gatcggctcg accccgaagg cctgccgatg ttcgtcgacg aagttcctca
19981 gctcttgagt cggcggtcga gctccgcctg ggcgaaaaac gcgctggcca gcttgaggat
20041 ctcattggcc cggcgcagct ccttgacctc gcgttccagc tccttgaccc gctgggcttc
20101 tgccgaggtc acgcctggtc gcgtgcctgc atcgacctcg tcgcgtctga cccactccag
20161 cagggtgtgc gccgaacagc cgatcttggg ggcgatcgac tccactgcgg cccacagcga
20221 agggtactca ccgcggtgct cctgcaccat ccgcacggcg cgctcacgca cttcagggga
20281 aaacttcgtt gacttgttca tagctccatt ctcttcaagg ttggagcctc cttaaaaacc
20341 ggggcggttc agaccgagaa gatcgagaca ggcagcgcgg cgggcaagct ggtctttcac
20401 gtctttgcag cgcttgccga gttcgagcgc aacctgatcc gtgagcgcac gcgggccggt
20461 cttgtggccg cccgtgcccg aggtcgcgcc ggcggccgga agcctaagct caccgaggcc
20521 cagatcaaag agatcaacga gatggtggat gcccagaagc tccccatcgg gcgaatcgcc
20581 gagctgtacg gcgtctcgcg caccaccatt tacaaagtcg caccacgcag ggaaaacgaa
20641 gcgggtgagg cgcagccagt gaagaagcca tgatcagaac catcctccaa cagtaccgag
20701 acgagtccgc cttcaaccgt gaccttggcg accgctttga gcgcctgatc cgggcctacc
20761 tcaagctcga tccccagtac gtcgccctct tctctgacgt ttggatgtgg aaggattggc
20821 ccgagcgcga ggcctatggc tacaaggcac cggacacagg catcgacttg gtggccaagc
20881 tccgtgagga cgagggcttt tgcgccatcc agtgcaagtt ctacgacacg ccgattccgc
20941 tgggcgacct tggcaacttc ttcaccctgt caggcaaggg cggcttcacg cagcgcctga
21001 tcgtcgccac ggccaatctc agcaagcacg cggccgacgc gctggaaaac cagaccatcc
21061 cggtcgagat gatgaccttg gaggacttgg acgcatcccc catcgactgg tcgcagtttt
21121 ccatcgagaa gcctgaccag ctccgcaagc tgcccaagaa agacccccgc gaacaccaga
21181 gcgaagcctt ggtggacgtg ctcaagggct tcaagaccag cgaccgcggc aagctcatca
21241 tggcttgcgg caccggcaag acctacacgt cgctgatcgt ggcgcaggag atggtcaagc
21301 cgggccagac catcctcttc ctcgtgccat ccatcgccct gctgtcgcag acgctgcgcg
21361 cgtggacggc tgacgccagc gtgccgctgc gctgctttgc cgtgtgctca gacagcaagg
21421 ccagccgcaa cgaagaggac atgcgcatct atgagctggc ctacccggcc acgacgaacg
21481 cggccaagct cgccaagtcc atgaccgaga cgcaggacag cacggccgtg accgtggtgt
21541 tctcgacgta tcagtccatc gaggtggtgc atcaggccca gcagaaaacc ggcatcgagt
21601 tcgacctggt ggtgtgcgat gaagcccacc ggacagcggg ctacaccgcg cccggtgacg
21661 atccttcggc tttcgtgcgc gtgcatgaca acgccttcat caagggcaaa aagcggcttt
21721 acatgaccgc taccccgcgc atctacgccg aggccagcaa gaccaaggcg gaagagtcga
21781 atgtgcaggt gtactcgatg gacgatgtgt ccaccttcgg ccccgttttt caccgcctgc
21841 gcttcgacga ggcagtgcgg cgcgacctgc tgtccgacta caaggtgctg gtgatcgccg
21901 tcgatgagct gcacgttagt caggtgctga accagcggat cgccgacagc ggcgacgaac
21961 tcaagctgga cgacgcggtg aaggttgtcg gctgctggaa cggcctaggc aagcacgtcg
22021 cggcggagga cggcatggac atcagcggcg acccacagcc catgcgcaca gccattgcgt
22081 ttgcgcagtc gatcaagcac tccaagctgc tcaccgccga attcgagaag gtgtcgaacg
22141 atctcggcga cctgatcgac tacctgcctg cgttggaagc caagcacgtt gacggcacga
22201 tgaacgtggt cgagcggaat cagcggctgt catggctcaa gggcaacatc ggcaaggaag
22261 agccggtgtg ccgcatcctg accaacgcac gatgcttgtc tgaaggtgtg gacgtgcccg
22321 cactcgatgc tgaaccgccc cggtttttaa ggaggctcca accttgaaga gaatggagct
22381 atgaacaagt caacgaagtt ttcccctgaa gtgcgtgagc gcgccgtgcg gatggtgcag
22441 gagcaccgcg gtgagtaccc ttcgctgtgg gccgcagtgg agtcgatcgc ccccaagatc
22501 ggctgttcgg cgcacaccct gctggagtgg gtcagacgcg acgaggtcga tgcaggcacg
22561 cgaccaggcg tgacctcggc agaagcccag cgggtcaagg agctggaacg cgaggtcaag
22621 gagctgcgcc gggccaatga gatcctcaag ctggcccagc gcgtttttcg ccccaggcgg
22681 agctcgaccg ccgactcaag agctgaggaa cttcgtcgac gaacatcggc aggccttcgg
22741 ggtcgagccg atctgcaaag ttctgcagat cgccccaagc ggataccgcc tgcacgcagc
22801 ccggcagcgc aacccggcgt tgctgtcacc acgcgcccag cgcgatcagc ggctgatccc
22861 cccacgtcca acaggtctgg caagcgaacc tgcaggtcta tggcgtggat aaggtctaca
22921 agcagatgaa ccgcgagggt gtggcggtgg cgcgctgcac ggtggagcga ctcatgcggc
22981 gcctgggctt gcgcggcgcc atccgcggca aggtggtgcg caccaccatc gccgatgcca
23041 aggcgccgtg cccgttggat catgtcaacc gggtcttcaa ggccgagcgg cccaatcagc
23101 tctgggtgtc tgatttcacc tatgtgtcca cctggcaagg ttggctgtat gtggccttcg
23161 tcatcgatgt gtttgcccgg cgcatcgtcg gctggcgggt aagcagctcc atgcgcacgg
23221 acttcgtgct cgatgccttg gagcaggcgc tctatgcccg ccaacccgaa cagaacgaga
23281 ccttgatcca tcactcagac agaggatcgc agtatgtcag cattcgctac accgagcggc
23341 tggctgaagc tggaattgaa ccttctgtgg gcagcaaagg cgactcctat gacaacgcgc
23401 tggcggagac gatcaacggg ctgtacaagg cggaattgat tcaccgtcgt gccccctgga
23461 aaaccaagga atccgtcgag ctggcgaccc tggaatgggt ggcctggttc aaccatcatc
23521 gcttgatgga acccctgggc tatatccctc cggcagaagc tgaggcaaac tactggaggc
23581 agcaagccag tcacgtcacc actgtggcct gacttaaacc aactggcctc cacgaaagtc
23641 ggggcggttc aatgctgcta tcttcctgaa tcctcgcgac tcggtggtgg acgtggtgca
23701 gtcggtcggc cgcgtgatgc gcaaagaccc cgcaggccgc aagaagtacg gctatgtgat
23761 cctgcccatc ggcatccgca aggacacgtc gccggaggct gcgctggacg acaacaagaa
23821 gtaccgcgtg gtgtggcagg tgctcaacgc cctgcgcgcc cacgatgatc gccttgacaa
23881 gcagttcgcc accatcgacc tgatgggcaa gagcaacggc gtggtgaacg tcatcggcgt
23941 cggtgctggc aatgaaaaga ccgatcgctt gcccgagcag cttgggtttt cgttcgaccc
24001 ggtggagctg ggcaagtggc aagacgccat gttcgccaag atcgtcaaca agtgcggcaa
24061 ccgtcgctac tgggaggact gggccaagga catcgccgag atcgccgacc gacaccagat
24121 gcgcattcgc gcgctgctgg acaagccgca cagcaagggc aagaaggcat ttgatgagtt
24181 cctcaagggc gtgcgcaaga acctgaaccc gagcgtcagc cagaacgacg ccgtggagat
24241 gctggcacag cacatcatca ccaagccggt gtttgatgcg ctgttcgagg gctacgcctt
24301 caccagcaag aacccggttt cccaatccat gcagaagatc atggacatcc ttgaggcgca
24361 ggccttggac aaggaacacg agacgctgca agggttctat gccagcgtgc gagagcgtgc
24421 ctcgggcatc accgacccca aggggcggca gaagatcatc gtcgagctgt acgacaagtt
24481 cttcaagacc gccttccccc gcatggtcga gaggctgggc attgtgtaca cgccggtcga
24541 gatcgtggac ttcatcctgc acagcgccga cgctgctctg caagagcact ttggcaccag
24601 ccttgccgac aagaacgtcc acatccttga tccgttcagc ggcaccggca ccttccccgt
24661 gcggctgatc gaaacaggcc tgatcccggc cgacgcgctg ccgtacaagt accgccacga
24721 gctgcacgcc aacgagatcg tgctgctggc ctactacatc gcagccatca acatcgaaga
24781 gtcattccac cgcgtcaccg ggcaggacta cgagccgttc cccggcatcg tgctcaccga
24841 cacgttccag atgagcgagc cgcagaacgg cgacatcgac gaaggactgc cggagaacca
24901 cgagcgggcg gatcgccaga aggcgcgcga catccgggtc atcgtgggca acccgcccta
24961 ctctgtaggt caggacagcg gcaacgacaa caaccagaat ctgaactatc cacggcttga
25021 tgggcgtatc gcggccacct atgcggcgca ttccaccgca acgctactga gtagccttta
25081 caactcctat attcgtgctt tccgttgggc ttcggatcgc atcaaggatg agggcatcgt
25141 ttgcttcgtc actgacggtg gctggattga tggaaattcg accgatggaa tgagaaaggt
25201 catcggcgat gaattttcag atgtctacat cttcaatctc cgtggcaatg cccgaggtca
25261 aggggaactc cgcaaaaaag aggctggcaa cgtttttgaa tcggggtctc gtagtaccgt
25321 ggccatcaca ttgttgatta agtcgcgaac tcacaaagga ccggcctcga ttcgatatca
25381 cgacattggc gactacctca cgcgcgagca gaagctggaa atcgtgactg gcttcgccag
25441 ctacaagact gtgccttggg tggccttgca acccaacgag caccacgatt ggattaacca
25501 acgcagcggc aacttcaacg agttcgtgcc gttcaatgag gaagccggag ccatcttcgc
25561 cacaaggacg ccgggagtct caaccgggcg tgatccgtgg gtctacaact acagccaagg
25621 ggcgctgatc gcctctgtgc ggaagatggt cgcctcctac gcgaacattt tgaacaccct
25681 tgtgtcgaat ggctcgctcg cgacggctaa gacagagaag gatgtggcgg gcttggtgga
25741 caagaatccg aagctcatca aatggactag agggttgcgg caatccattc tgaggcagcg
25801 ggccgcagag ttcgtgcccg agaacctctg tctggcgagc taccgaccat tctccaaatc
25861 gtgggtgtac ttggacacga tgtggtctga gtaccggccc accaagctgt atccaacacc
25921 tgcccatgaa aatctggtca tccagttgcc ggggccgggt gaggatcgac cattctccgc
25981 gctggtgacg cggctcatcc ccaacatcca cctgctgcac ggcgggcagt gcttctccat
26041 gtattggtac gagaagcaag gggctaacgg tcaggtcaaa ggactgtttg acgccgccac
26101 ggttgtcgat ggctacatcc gccacgacgg catcactgac gtggcgctcg caaacttccg
26161 caagcactac ggtgacgcat ccatcaccaa ggaagcgatc ttcttctatt gctatggcgt
26221 tctccactcg cccgaatacc gcgagctgta cgcatcggat ctcaagaagg tgctgccacg
26281 ggttccctac gcgcctgact tccgtgcctt cgagaaggcc gggcgcaccc ttgcggcgct
26341 gcaccttgac tatgagacgg tggagccgtg gcctgtcaca gaagaggcaa agcccaaggg
26401 cgatctcaac gacttggcct actaccgcgt cgaaaagatg cgcttcgcgt caaagggtgg
26461 ccgtgagaaa gaccgtagcg tgatcgtgtt caacagccgg atcacgatca agggcatccc
26521 cgagcaagcc tacgactaca tggtgaacgg gaaaagcgcc atcgagtggg tgatggatcg
26581 gtatgaggcc gccaccgaca aggaaagcgg catcaaggac gatccgaacg agtggtgccg
26641 agaaagtaac gaccccgcct acatcctgaa cctgctcaag cgtgtcatcc gcgtgagcat
26701 ggatacggtc gagatcgtcg gaggcctgcc ttcgatccag tgatgtcagt attcatcggt
26761 gtaaggctgc acagatagcc gcaccatgtc gagcaaatca gggaggaata tgagcgatca
26821 atacacctac gcgagatttt ggcgatgcgc gctacaagtc aatcctgtcg gctacaacgg
26881 cacctacagg ggagccgatc acgggctgga tgagggcggc tacaaccaag cgctgcttca
26941 aaagtgcctt gagctgggta tcacggttgt cgggttggcc gaccacggca gcgtggccag
27001 cgtcgatgcc ttgcgtcagg tgctacagcc gcgcgggatc gtggtatttc ccggcttcga
27061 gatcgcctcg aacgacaaga cccattacgt ctgcctgttc tccgaggaaa ccacagggca
27121 gcaacttgaa cgctaccttg gcaatctcga tcttcttgac ccaacagacg gtgttcgccc
27181 gtctcggttg agttccgagc agttgatcga gaaggtcgat caactcggag gcttcatcta
27241 cgctgcgcac tgtacgtcgg acagtgggct tctaaaaaac cggctcaacc atgtgtggaa
27301 gctccacaag ctccgcgcag cccagattcc ggggccgata gatgacttgg ctggggtgga
27361 aagtgacttc taccgtaggg tgctgctgaa caaggatgat gcctaccggc gcgagaggcc
27421 cgtagccgtc atcaatgcca aggatgttgc aaagccggag gacttggagc agcccggtgc
27481 cacttgcttc atcaagatga cgcggccgaa ctttgccgcg ttcaaggttg cctttctcga
27541 tccgggatcg cgaatccgcc tcaactctca gcaggcccaa agcccgattg gcaaggttgt
27601 acgcatgacc gtggcgggcg gctaccttga tggcgtcagg gtggactttt ccgaccacct
27661 caacacggtg attggcggcc gtggaacggg taagtcaacc ttgctcgaat gcctgcgctt
27721 cgccttggac ttgccaccca aaggcaagca ggcccagaag ctccaccaag agatcatcaa
27781 ggagaacctt ggtcgctcgg ccggacgggt tgagctgaca gtagtgtcct ctgcccagaa
27841 cggcaagcag tacaccatct cgcgccgtca tggcgagccg ccgatggtgc gcgacatgga
27901 tggcaatgtc tccaccctgc ttccgcgcga cttgctgccg ggcatcgaca tttatgggca
27961 gaacgagatt tacgagctgg cccaagatga aaccagccgg gtgcagttgc tggatcgctt
28021 ccttcctcaa gacggacagt acgagtccaa gagcgccgac gtgcataggc gcttgaagga
28081 caaccagcag aagctcacga agtccctgac cgatctcgac gagctgaatg cacaggttga
28141 gcgcttgccc aagctggaag agcagcttcg cggttttgat gagctgggga tcaaggagaa
28201 gctggccaag acctcattgc tcgcgcgcga gcgagagatt gccaagaccg cgaccgaggg
28261 cgtacagaac tttcgcgacg cacttacaga cctgcgtgac agcttgcctg accttgactt
28321 catcaacgat gaggcgcttg agggcttgcc tgacgctgcc cagttgctcg ccatgcgcac
28381 gacgctggat ggactcaagc aggggttcac cggccatctg accgcgatgc aggccttgct
28441 tgatgacaag gcgggacagt tcaccaccca gcatgacgca tggcagcagg cgattcaggc
28501 gcacgatgtc gagttagaga aggcgctgcg cacgttaccc gccactgctg gaaagagcgg
28561 gcaggaggtc ggtgttgcct atcagaagtt gatgggggag atcgagcgca tcaagcccat
28621 gaagtcgcgg gcgactacgc acgagtccca gcgcgacacc ttgcgtcagg aacggcgcaa
28681 cctgttggcc gagctgtcag atttgcgtgc gcaacgcata caggcgttgc agaaggccgc
28741 gaagaagctg aacaggcgac ttgagggcaa gctcaaggtg gagatcgtgc cggaggctga
28801 ccgcacgccc ttgatgacct tcctgctggg ttgcaagctg gacggtgttg gcgaaaagcg
28861 gcttgcgttc attgaggaag ctgagacgat cagcccactg tcgctggccc agtcgattca
28921 gaaagggtct gccgacgtgc aactcgattg gggcgtcacg cagatggtgg ccgacgcact
28981 caccaagctc cagtcgtctc agcttatgga gctggaggcc ttggagctgg agcatcgagc
29041 ggacatattt ttgaatgtcg ctcacggcca agccgatccg gtattccggc cgctcaacaa
29101 gctctccacg ggtcagcagt gcactgcaat cctgcacatg ctactgcttg agaacgttga
29161 tccccttctc atggatcagc cggaggacaa ccttgacaat gccttcatcg cagatcggat
29221 cgtcgccgag ttgagggagg caaagaccag tcggcagttc ttgttcgcta cacacaacgc
29281 gaacattccg gtgttcggtg atgccgagtg gattggcgtg ttcacggccg ctgaaaacca
29341 agggcgtctc gggctggaag cgcaaggctc gattgacgtt cccgtgattc gggatcaggt
29401 ggccagcatt ctggaaggcg ggcgcgacgc cttcatccag cgcaaagaga agtacgagtt
29461 ctgatgccct gccctacgcg ctgataatca aggagactgc cttgtagcgg cgttttcctc
29521 cctgacagcc cgcagtcttt caccgcctcg ctctgcgagg cggctttctt tccgggctac
29581 gagaacagct cggagtgcgt cccgctgcgc acgaaaacga ccaagccgct cttgcccgag
29641 tcgtcgagcg tgtagatcag gaggaagtcg ccgccgacgt ggcactcacg atggcctgcc
29701 cagtcgcccg tcagggcgtg atcgagccat tcaggcggca gcggcccgtc gttggcgatc
29761 agcagcgtca tggcctcttt cagccggttc atgtcgtacc ggccggaatg agacaggcgc
29821 tgccagtcct tgaggaagtc cttggtgtag tccgacgctc ggggcaggtt tgcccgctta
29881 cttgcggctg gcttcttcga ggtcattcag caaggcgtcg gcagttgcga agcgagcgcg
29941 acggctcttg atgatctcgt tggcctcggc gatggcgacg cggctggtgg cgttcggtgc
30001 cttgagcgcg aacggcagtt ccttgtcggc gacaacacgg gtcaggaaca cgcggatcgc
30061 atcggagacg gtcaggccca tcgaggccag cgtttccgca gcctgcgcct tgacgttctc
30121 gtccacacga acgtgaacca tagtggtggt agcagccatg acggcctcct gttgcgactg
30181 attgagatac attgtatcgc acgccgcgca caatcgcaag gcgacacccc tccccccccg
30241 gtgccccgtc tctaggtatg tatataggta ggtatatata tacctaccta cagcgaccac
30301 ggcaggagct tggcgatgtt gcgggcatcg tcgaggccgc gatggtgcga gccatcgaga
30361 ggcaggccca ccatctgcaa cgcgcgggcc atccccactt ccttgatctt gcggccctta
30421 gcaaaccggc gcttgaggtt cacatgctcg aacgctgcga gcgggctttc gatgccgtgt
30481 cgctcgcagt cacgcgcaag ctgcttggcg tcgaattggc cccagctccc ccacgttgcg
30541 cccggtgcct gatggcgttg ggcgaagctg gccagccgtg ccgcgaccgc tgggaacaac
30601 tcggcaccgt ccacgtcggc ctgctggatg ttggtgagct gccgacagaa cggagtgagc
30661 tgagggcgta ccacggggcg caccagcgcc tgaaacgtgt cgagcacgct gccctcaacc
30721 gtagcccaaa ccgcgccgat ctcgatgatc tccatatcgc tcgccgggag gccatcggca
30781 tcgtcgcagg tggcctcaag gtcaatgacg agcaccaccg gggtcacaga atccccgcga
30841 gggcatcgac cagcgactgc cctcccctgc gatccagcca gcgcgcctgc atcccgaagg
30901 cctgcggccc gtcgaagtcg caccgcttgc tgtcgcctac gaaaaccgtc tcagccggtg
30961 cgcagcccag ctcggcgcac gcgagccggt acatcgtcgg gtgtggcttg gctaccccga
31021 cctcatacga cagcacgtag gcgtcaagct ctggcaagag gccgcgcacg gccgggccgt
31081 actcataggc aaggttcgag cacaccgcca agcgcagccc tgctgcccgt gccttgacga
31141 gaacgtcggc cacctcgggg aacaggcgca ggccggacag ctcttcggcc aagtcggctt
31201 ccatgatgtc caagctgctt tccacgccca gctcgacggc gagggtcgcc agtggcacgt
31261 cgcgcgtgag gcaggcgatc cgatccaccg gccgcccggc cgcgtccacc agatgcccgt
31321 agggtgcagg gcgcgtggtg tagcggatca gggtgccgaa ggcgtcaaag acaatggctc
31381 ttgttggctt catgtatata tatacctacc tatataccta catacctact cgaacagctc
31441 gcgctcgaac tcgacgccag ccaccaccag cggctcgcca ctgggccagc gcttgggcgg
31501 ctggtgatcg ctgatgacct gcacgtcggt gtcgtcgttg accacggcca cgtcggcggc
31561 gtgtaaagcg gcttgcttgc tcgcccgctc gaagcggcag gtgttggggt cgaatgtcca
31621 aaagcgcatg tcagcctcct tggtcttgag ctttgcggcg ctcgtgctct tcgagcagcc
31681 gctggtagga atcgaattcc ggcgtgccgg gcgtggcgaa gttgggcagc atcagcggct
31741 cgtactcttc ctcgatgact ggacgcccct tcaccggctc gggcatcagg tcggccagca
31801 ggcgcaagac ggctctggtt ccgttgcgga tcgcgacggc gttcttgttg tcggtggcgg
31861 catagccctt ttggatgccg gtgcggatga cgcccaagcg ttcggcgagc gtgtcgagtt
31921 cgtactgggc taccgacttc aagtgctctt cgtcttgctt gacgcgccac tctttccatt
31981 cgtcctgttc ggccggagtg aggacggcgg ccacttcggc gggcagctcg cgggctgcgc
32041 ggtcgaactt ggccaccacg cgctgcacgt tcttgccctc cgggaaatct ggcgttacct
32101 cgcgcacgcg gcgcaggcac tgcacggttt ttccctcgtg gtagttgcca tcttggtcac
32161 ggtggcggac ggtcttgaac tgcatgggct gcgttctctt cttttagttg gttgcgtatg
32221 tgtagaacta tacgcaaaag cgcgaaagtc tgctaccatt cgcttgtggt cggtaggtat
32281 atatatactt accgagtccc agcgccgggg aggaacccgg caggtcgatg gtcagccgct
32341 ttgctgctgc gtcggtatgt atatatatct ataggagcac cccatgatct tcgcgtgtgt
32401 gaacaccaag ggcggcgtcg gcaagaccac gaccgctgtg catttggcag tgatgctggc
32461 ccggcagggc aagaccctcc tgatcgacgg cgacccgcag gcctcggccg cgagctgggc
32521 tgcttggcgt cgtgagacgc aatacgaccc gtcgcccacc accacctgcc tcgctggtaa
32581 ggcgatcttg gccgaaggca agcagttggc cagcggcttc gagcatgtcg tcgttgatgc
32641 cggtggccgt gattcggttg gtctgcgctc cgcgctgctg ctggcccagc gtgccgtgat
32701 cccgattggc gcgagcaatc tggacgctgc cgccatgacc gacttgctgg aagtggtcga
32761 gctggcccgc gactacaacc ccgagctgga tgtgcgcgtg ctgctgaccc gtgtcgatcc
32821 gcgcaccaag gatgcggccg aaatgctgga attcttggcc gagcagaagc tgaccgtgct
32881 gccgaccaag gtgtgcgagc gggtggcttt ccgccgcgcc atcggcgaag gcgcgagcgt
32941 tcaggagctg ggccgcgatc aagccgccat tgccgagatg gaagccttct tcaaggaggt
33001 gatggcatga gcatgaaggg caagcccaac acggcgcagt tcaagccgcc caaagacccg
33061 accgccttcc ttgaaggcgg ggaggcggac aaggccgaaa agccgctggt ggcacctgcg
33121 gccgtgacca cgccaccggc cgccacgccg cccgctgccg aggaaacgca gcgctacggc
33181 cgcgcacggg tgcaaaaaat cttcaacttc cccgaggaac tggctgatcg cctgcgccgc
33241 gaagcgctca agcgctcaga agagaagggc ggccgggtca cggagaagga catcgtgatc
33301 gaggcgctgg aagccttcct caagggccga taggtatata tatacctatc tatgtatata
33361 tataacgatt tccagtatgg actatagtcc atacaagtga cgacaccaac accatgcagc
33421 gacaggcgca acgaaacatg atattgttgc gattgggcgc ggaataaggt ataaacgatg
33481 ctgacgacaa ctgctagtgt ggtcgcgccg aaggttttga aggaactcat cgccgctggg
33541 tcggtttccg ccgcccgagt ggaacccggt gacaagggcc tcttgatcgt ggtgcgggcc
33601 ggaatgaatg agcgagtgct gggtgctgcc cgtggcggcc ttcggtactt ccagagtctc
33661 gatggagctg caagcgtttt gcagtcctac gggatcatga agtttgatgt gaacacggag
33721 cactgggtgc ccaagacgat ggtgcggggc tacaagcaag ccccggcgtc tgtggatgct
33781 gacgagtgac cgtcatggca aaggagagag ctgaccagac agcacaaaac tggagagtca
33841 gaaacgacaa agcccgcttt ggcgagcggg ccttgacaga gaaaccgggc agggtgccca
33901 gacacgtaca ggattcatct tggcggatga gttctgtacc agtgcaatta agcgactgac
33961 tatgcttcga ttgtacgtgt cttaagccct gcgcgcaagc gtgcgcacgc ccctatggga
34021 cgtgtgatga ggggttatgg caggtacaac ggcacagaaa ctagacaacc agaccgcaga
34081 tcgctttttc cagtcgggca ccgcgctcaa tcgcgtgctc acggaagcgc cctatctgcc
34141 gcgttgttct gacgacaaga cggccacccg agtccggccg cgcgaatacg ccattcgcta
34201 cccctacatg caggtcaatc ggcccggctt cgtgagctgg ctgatcttcg accttgacca
34261 tgccaaggcg atgatctggg aggacgctgg ccttcctgcc cccaacctga tcgtccgcaa
34321 ccgccaaagc ggccacagcc acctctacta cgcgattccc ccggtctgta cgaccgaggc
34381 cgcccgcagc aagcccatcg cctacatgaa ggccgtctat gaggccttcg ctgcccggct
34441 cgatgccgac accgacttcc acagcggccc cgtggccaag acgcccggtc atccttggtg
34501 gctgacgcac gagctgcacg cccacgtcta cgagctgggg gagttggccg actacgtgga
34561 cttggctgtg tccagcccgt ggggcaaggg gcctcagttc gacgaggtga gccattcccg
34621 gcactgcatc ctcttcgagc acctgcggca ctacgcctat tccatcgtga accgtgagcg
34681 cgagcgcggc tcgtttgcca ccttcacgcg gctgctcgaa gcctacgcgc acaaccgcaa
34741 cagcttccag aagctgggct tcatggacaa cctggcgcag tcctcactca aggccacggt
34801 gaagtccgtc gcccgctgga cgtgggatcg ctacaccggc tgcggccggt gccaccgggg
34861 cgtgatgcag ctcgacaagg acttgccgct gatcgagcgg cagcgcctcg ccgccgcccg
34921 cacccacgac gtgcgccaca agactaccga gtccaaggtg cgcgccgcgt gccgcctgct
34981 gcaacagaag ggcgaagccc tcacgcaagc cgctatcggc cgcgtagcgg gcctcacaag
35041 gcagacggtg gccacctaca agcatgtgct cgaagaagtg ctcaagcccg tcgccgtggc
35101 gattttgggg ggcgcttcgg gcaaggccga ggatgttaaa catggtgcac atcaggtaac
35161 tgccgccccg cagggggccg gggttctggg tgcagcttcg gtgtcccttg agctgtttcc
35221 tgccgggccg ggtgtcgtgc ctgtgctgga tggctgagat ggagccggtt ttggttttga
35281 gtagcccaag cgtttttcaa acgcgagtag ccgcaagtgg gttgtgggta agtccgcagg
35341 acttatccat catcccgcgc gcagggcgaa gcccggaggg tgttccgccg cgcgtaagcg
35401 cggccccccc ctcagttttc ggcgtggcgg ccgtgtcggt tgaatggagt tcggaggatg
35461 tagcgtatgg ctcgacggtc ttttgacaat gaaacgctcg catgggtgcg ggagatgccg
35521 ctttcgcagg tgctcgacaa gctgcgcgac gatggtcagt tgttctggcg tcgcgatctc
35581 gacttcgtgc cggagaagga caagcggacg gtgcggctgt ttttgtcgtc gccctcgggc
35641 tttgcatggg aagttctggt gacgggcctc aagtggtttg acgtgcgcgc agggaagggt
35701 ggaggtggcg gcatcgacct cgtgatgcac ctgctgggca tcgacttcgt gaaggccgtc
35761 aagctgcttt cgtccggtgc cggtgtggct ggccagcgtc gtccagttcg gccgcagtga
35821 aattcgggcg gctcgctgct gcgcatcgac cgggctctcg tgcttcgcat cgagcctcgc
35881 aagcgagtct cgacccctgc gggcttcgat cttccctccc ttgcggtcgg cctgccgctt
35941 tcgccgtccc ggcgaccgaa accccttcgg tttcggcatc ccgcgtgggg tcttgcccca
36001 cacgtcgcgg gggaatgtgg gcgggctttg cccttgacat ccccctctga cgtgaggctc
36061 tggtcgttcc agccgcatca agggtgcgct gcgccgtgat cctcacccgt tcggtgctcg
36121 ggcttcgccc tgtgctccgc gtgcggcttc cggtcacgcc cttgacccgg cttccacttg
36181 aaaaccgtag gtatgtaggt aggtatatat ataccgatgg atagtgaatc aagcggcttg
36241 tgtggcgctg ggggagtcgt gacgcaacga tggtggcttg ttcaaccacc ggagatcgac
36301 tccatgcaaa ccaccaaaac caccccgtac cactgcgccg aggtgcggcg ctctgtgccc
36361 gtgttccagc ggatcgaatg ggtgagcggg atcggccaag acgatgccga gccggttgtg
36421 ctcgccgagg cctgcgcgct ggccagccgc tgcccgaggg tcgcgcactg tccgctgacg
36481 gccgacgagt agggcggctc gatggccgcc ccacaagccc cagcttgcgg gctggggcgg
36541 ggtcacggtc agtccttgag caagacgatg tggtgtgtga tgcctgtggc gatcagcaca
36601 gcgtgctcgt tgttgcggaa cgggtagccg ttgtgtgcga tgacgatgat gcgcatgaaa
36661 ttcacctcct ttctgggcaa gttgcctcac acctatttgg ggtagagcaa gcagtcgtgt
36721 caccagccgc catttcgatc acggtaggtc gagccgggtg ttcatatcga gatcgaaccg
36781 accatacggg ttgacgtgtt cccagatcag cggcgtcagg gcggcgtagt cgcgtggtgt
36841 gaacctgccc tgccaatgcg gcagggccaa gaccttctgg atcatcagcg tgttgatgta
36901 gaccatacag ttctggatca agtgcagcgc gagcatgctg acctcgtgat cctcgcggcg
36961 gttgctcgcc atctcgcccc ggcgggcgaa gaacacgaag tcggtcgcgc cgttccactg
37021 ctcgactacg ttcagccctt cgttgatttc ccggcgcaac gcctcgtcgt gcaggtagcg
37081 gcacaggaag atagtcttga tcgccttgcc caactcagcg aatgccttgt aggtcgggtg
37141 ctgcacgttc ttcttggtga agcggcgcag gatggcttcg gtgtccgctg tccccaggcg
37201 cagcgcggta gcgtacttga ccatctggtc gtactgttgc cgcaccgagt cccagtcgat
37261 gggcttggtc agaatctgtt gcaggttcgc gtagacgtcg gccttgccgg tctctggccg
37321 gtacagcttc tgtgagtgga tggccttcag ccgtggcagc aactggaagc ccagcaggcg
37381 gcagaaggcg aacgccaccg tgctctggcc gtgcgaatcg acatactgcc gatccacctc
37441 catctcggtg caatggtgga tcacgccctc gatcatcgac gccacctccg acgacgacgg
37501 cgacttgagc tgcgaatgga tgcacagcga gctgcgctcg acatgccagt agatcatcac
37561 gccgcgcccg ccgtagcgga cgtgccattg cgtggtgagg ttctgatccc acgcgccgaa
37621 gtgtttcgag tccgacgcgc aagcggtggt gccgctaccc cagatcgccg ggttgcgggc
37681 ttgcagcgtg ccgtctgcga cgatggcaat cgcgcggcgc atcgcgtcca cgctgatgta
37741 acggcggcgc acataggcca ggtcgcgcgc cgtggtgccg gaatccagcc cggccatgcg
37801 ctgcaagcca gcattggtgc ccaggccgtg cagacacagg agcaggcgcg gctgcaacac
37861 cgagcgatcc atcgactcgt aggaggtcgg gcttttcagg gcatcggtaa agctcaaccg
37921 cagatcggtt tccttgacca tatcgagcag gctggtcatc ggccagagga cattgagttc
37981 ggcctttagc gcggtcagat tggggggatc gggttgcgca tcgagcggcg tcagcgtgat
38041 ccagccaccg cccttgctgc tcagccggac ggatggattc ttcttcaagc cagcgtcgaa
38101 ggtggacagc gccgcgcgca tttcggcctg caagtcggcg atgaagcgct ccacatcgag
38161 aggcaggttc agcgcccggt agtagtcctc gcggttttgc tcgaagtcag ccggcagatc
38221 gtcgtcgggg ttgcggtagc ggttcgcgcc gaccacccag atttccttgc agcgcagccg
38281 ctcgcgcagg gcttccagca cggcgatttc ataggtgacg cggttgaccc gatcccggcc
38341 ggcggcgtcc gtctccatga cggcttctcg ccacaggcca cgtaccacgc catcgagcgg
38401 cacctcgatg tcggctggga aggtatgcac cttggtgtcg gcaaagcgct tcaccagtgc
38461 gagcgcgtcc atcaccgggc ggtggcggtc gttgttggag cggaatacca gcgcggccag
38521 caaggtcggt actatgcgcc ggtagtggcc ctggtacgaa ttgcggatca cagtgcgcag
38581 cgtgatgcgg taggtcgggc cggtggcctt ccactccttg accagatcgc gcagcgtctg
38641 ctcgccgacc actggaaaca ccacgtcgcg caccacgccg tccggctggg ccaaggtggc
38701 gtcggccaga ttgaacagca ggttctgctt gccggacacg cgcttgaggt cctccagcag
38761 ttcgcgttcg accttgcgtt cggcacgcgc gccgatctgg tggatggtct cgatcagcaa
38821 gtccaccagg tcgtcggtca ggctgcgggc gcgcaggtgg acgaaagcgg ccagccaggt
38881 gaggcgcgct gcatcgggat gtcggcgcag gtcgcgggga acctcgaccg acacacgctg
38941 gcggcagcgc tccaggtcac gcggcgaagt ccggtcgaac agatcggcag acagctcgat
39001 cccccggatc agttcgagct tcgccaactc atcctgcatg ctggcaaggc ttgggcggcc
39061 gggactgccg cgcagtttca gcaagacggc cggcgcgttg cctgcggctt cgccttgagc
39121 atcttcaacg gcgctctccc cgtggcccga ttcttctggg cgcagcaagg catccaggcg
39181 ttcgcgagtc gcgggcggca gccgcccata cacgcagcta tggaagcggt cttcgtggga
39241 gcgcaacgca ctgcgcgcga tgcgctccat ccggtctggt ttcggcggct cgatggcgag
39301 ttcgcggcaa cgtccttcca gccgctcgat catcggctca atgtcaccgc caacttctcc
39361 ggcaacatga tcacgcagcc actccgtcag catctcggca tcggctaccg tcgcttcgcg
39421 gaagccgaaa cgcacgcgga tttcgccgcg cagccgctcg gcagtgcggc ccgtgaggaa
39481 ggcttcgcca tcgatgggcg cgggtgcgtc gagttgtttg gcgagcgcgg ctatgccctg
39541 tacctcgact tcggtttcgt cgcgcggaaa acggccgcga tcgcggaaga aggtcagcag
39601 gatggcaaag cccaaccggt tcgcccggtt tttggtcatc accagttcgc gttcggctgg
39661 cgccaatacc cactgatctt ccttactgcc gccgccgtcc gccataccgc tacgctcctg
39721 ggggcactga cgcgggccag ccggcccgcg tcagagtttc gatcaaggtg gtccgcttca
39781 cgccgaagtt gcggcacacg gctgccttgg acatgccacc ttcgagcgcg gcgataatgg
39841 catccagctt ctcgccggtg attgcctgcg gccgcccacc gatccggcca cgtttgcggg
39901 cagcagccag gccggcaacg acacgctcct ggatcaaggc gcgctcgtac tgcgcgagcg
39961 cgccgaacac ctggaataga aactcgcccg atggcgtggt ggtgtccaga ttctccgtca
40021 gcgagcggaa cgccacccgc ttgtccttga gcgaggtcac gatggtgagt aggtgcgaca
40081 gcgatcggcc gagccggtcg agcttccaca cgaccagtac gtcgccgggc ctgacgaatt
40141 cgagcgcctg caccaagccg gcgcggtcgt ccttcgcgcc ggaggcgtaa tcctcgaaca
40201 ggtgacgcgg atcgacgccg gcggcgagca gcgcgtcgcg ctgcaagtcc gtgctctgcc
40261 ggtcggaatc tgacgacacg cgcatgtaac ctactaacat aagcggaaaa ccatcaagac
40321 gcggtttccg catggtagcg tctggcgaca cagttttccg cacaattttg cggccactcg
40381 gagcttggtg cagagggctg ttgaagatct gtcgacaatc aaatgttttc cgacaggcct
40441 tggcctagcg cacgcccgcc ttgcagcgtt ctgtgaatag cgcttagtaa tgacggcgta
40501 tatactttgt tagtatcaag tggcaggagg ccccgatcat gtcaaaacaa gccgttttca
40561 cgatgaagct ggagcctgag ttgcgcgccg agtttatggc cgaagccgag gcggcccatc
40621 gcccggcgtc acaagtgctg cgcgagctga tgcgcgagtt cgttcagcgc cagcgcgagt
40681 cgcgcgagta cgacgagttc ctgcgccgca aggtcgaagc cggccgggct tcgatgcgcg
40741 ctggattggg gcggtcgaac gatgaagttg aggccgaatt cgccgcacgg cgtgccagtg
40801 tggcgaggca gtcgtgagag ttgtctggac gcccgaagcg cagcaagacc gtgccgatgt
40861 gtgggactac atcgcagccg acaatccgcg cgcggcggcc cggatggatg agattttcag
40921 cgacgcggcc gcccgcttga tccagcaccc catgctgggc aagccgggaa agattcccgg
40981 gacccgcgag ttgatcccgc acgaaagcta tcgcctggtg tatcagatcg acggcgaaac
41041 ggtgtggata ctgacgctgg ttcatactgc ccgcctgtgg ccgcctgtgc gcgattaaga
41101 gatgatcatg gcaacaatga aacggcgcgt tgacagactg ctttcgagcc agaccgcggt
41161 cggcggcagg cggccaggag cggtcaatca ataacccacg aatccagccg tttagccgtc
41221 agctttggag caattacctg ctgtcctttg gaaagctacg acagaccagc cccgtcgtat
41281 ttcactaaaa ataccctcaa cctggaagcg tcaggagttc cggcacatgc tcgtccaacc
41341 agtcatcgag cgatgacaat acggttcgga aagagcatcc cagttcagtc atcgaatact
41401 cgactttagg tggaatcgtc tggaaatcat ggcgagcgac caggccattc atctcgagcc
41461 gacgaatggt ctgggtcagc atcttttgcg agataccttc gatttcctgc atcaattggc
41521 cattgcgccg cggaccattt gcaagggcat gcattaccag tagcgcccat ttgtcgccaa
41581 tcaactcaat gaatttcctg gatggacatt gcttaaagca cggattcgtt ttgcgctcgg
41641 tcatgattga aagcctatag gcaccacaag gtgcgtactt taccattgta aagtagctca
41701 atacactgcc atcagcacca aatttatgaa ggctgaatgc tgtgaaatcc ctgtttcccc
41761 gtaccccttt tctcgctggc agcgacgttg aagccaagcg tactgagctg ctgcattact
41821 tccatgccac ctttgatcgc tacgagtctc tattcgaggt gctctcctgc gatgaggctt
41881 attacaagaa gcccatcaca ttgcgacatc ccctgatttt ctacttcggc catacggcca
41941 cattcttcat caacaaattc ttactcgccg gcctgattga taaacgcatc gaccccaggc
42001 tggagtccat gtttgccatc ggcgtggatg aaatgagctg ggatgacctg gatgacgccc
42061 gttacgagtg gcccacggtt gcagaggtac gcgcctaccg caacaaggcc cgtgaagtga
42121 ttgatggcgt gattcggtac acgccgtttt ccttgcccat cggctgggat gacacattct
42181 gggtcgtact gatgggcatt gagcacgacc gtatccacct ggaaacctca tcagtgctga
42241 tgcgtcagca tgacctgaag tacgtcaccc cccatccgga ctggcaaccc tgccgcgaca
42301 gtggcacagc acccacgaac acgctggtga acattcccag cggacgggtg gtgcttggcc
42361 gagcacttac tgaccctatc tacggttggg acaacgaata cgggcaccat caggctgacg
42421 tgccaacctt tcaagcctcc cgctacctgg tcagcaacgg cgaatttctc gagttcgtga
42481 cagccggtgg ctataccgac gacagcctgt gggacgaaga aggtttgggt tggcgccgtt
42541 atgctcgggc agagtttccc acgttctggg tgccgtcggc tgatggctgg aagctgcgct
42601 tgctggccga agaagtgccg atgccctggg actggccggt ggaaaccaat tgcctggagg
42661 ctcgtgcctt ctgccgctgg aaagcgcggg aaaccggcca atcggtgcgc ttgccgactg
42721 aggacgaatg gcatcggatg tatgaccatg tccatctgtc tgacgtccct catgatgcgc
42781 cagcggctgc caatctgcat ctcgaccact gggcctcgag ttgcccggtc aatcgattca
42841 tccacggtga tttggcggat gtggtgggta atgtctggca atggtgcgaa acgccgactt
42901 atccattcga cggcttcgac gtccatccca tctatgacga tttcaccagt ccgacctttg
42961 atgaacggca caacatcatc aagggcggca gctggattgc cacaggtaat gaatcccgcc
43021 atgcctcgcg ctatgccttc cgccgtcact ttttccagca tgccggcttc cgttacgtgg
43081 tgacagacac accagtgcca aaccccgtgt cggcctatga gaccgatgcc atggtttccc
43141 agtacgctga attccactac ggtgaaacga cccttggcgt cccgaatttc ccgcaggcca
43201 tggcacaact ggccatcgac ttccatcgac gtcacggaaa cggcggcaag gcgcgcgccc
43261 tcgacctggg ttgtgcgacc ggccgggcaa gttttgagtt ggccaagact ttcgacaagg
43321 tcatcggcat cgacttttcc gcccgcttca tccaggtggg tatccgattg gccgaaaccg
43381 gcgccatccg ctacaccatg cctgaggaag gcgagctggt cggctaccac gaacgccgcc
43441 tggacagcct gggtctgctg gagactgcgc aacgcgtcga gttctggcaa ggcgatgcct
43501 gcaacctgaa ggacatcttc agcggcttcg acctcatcct ggctgccaac ctcatcgacc
43561 gactttacgc accgcgccgc ttcctcgata ccgttgctga ccgcctgaac tcaggtggcc
43621 tgctggtact ggcctcgccc tacacctggc tggaggaata caccaaacgc tccgagtgga
43681 ttggtgggtt caagaaggat ggagaatccc gcaccactct ggacggtctc aaggaaatcc
43741 tcggccgaaa gttcgtcatg gtcgaagccc ccctctcggt tcccttcgtc atccgcgaga
43801 cgcgacgcaa gcatcaacac accctgagtg aggtaaccgt atggaagcgc aagtgatgcc
43861 attgaccaac ccggaccact accgagaccg tgccctgggt gccctgatgg gcgcttttat
43921 cggtgatgcc ttgggtattg gcccccactg gtattacgac ctggaccaaa tggtcgccga
43981 ctacggccca tgggttgact cctatacgcg ccccaaacct gggcgttatc acgagggagt
44041 cgagcccgga cagccttctc agtcgggcat cttgctggag atgacgctac gctcttcggt
44101 ggagtgtggc ggctatgacg aagcagactt ttgccgacga ctggatacgg agctttttcc
44161 taaactggac ggcaccccga tgaatggccc tggtggctac accagccaat cgattcggga
44221 tgcctggcgc aaccgagtcc aagaagggct ggcttggggg agcttcggta gtgatgtcga
44281 taacacggag gctgccgaac gtattatcgc tattgcggtg cgctatgcgc tcaatccggc
44341 caaactggca tgggcagtga ctgccaatac agcgctaact caaacaaaca gtaacgtcct
44401 gactacaacg accacatacg gtgcggtact gggtatgttg gtggaagggc atcgatttga
44461 tgccgacata tccgacaaac tcatggaccg tatcaaggcc gacaaacgaa tcgctcgctt
44521 caattcagca gtgcaaccac tccacgctgc cgctcaggga aggctagagg tacaaataca
44581 caccgactgt cagccatgta tggagacgtt ctttccttct cacgatgcct tggtgacgcc
44641 atcgggcgtt gcccgggcag cacacgactc gggaattcgc atcgagcctg cctccaaagt
44701 aagtttgctc tacggccttc cttgcggggt ccatcaccag tttccagctg cctactacct
44761 gacggcccgc ttccaagacg acttcgaatc tgccgtgctg cacgccctaa acggtggtgg
44821 tcagaaccag gcacgcgcca tgctgacagg cgctctcagt ggcgcgatgg ttggcctgtc
44881 cggtattccc cggcgattca tcgatggcct agagcgcgct aaagtgctac tggcacttgg
44941 cgagaggctg gtaggcgata tgcaaagtca ggcgcagaaa aatggctccc ccggatattt
45001 catcgatgag agacgttgcc catgaacccg tcgcagcctt tgaccattga aatcgtttcc
45061 gacgttgtct gcccgtggtg cttcataggt ttgcgccggc tggacttggc cctcgaggct
45121 gtccggcgca ggcatcctga tattcgttgc atcaagcgtt ggtgcccgtt cttcctgaat
45181 cccagcgtgt cgccagaggg tgagccttac ctgcctcacc tggtgaagaa gtttggtggc
45241 cccgaacggg ttcaagcggc attccaacat gtgcgtgatg ctggcgctgc ctatggactg
45301 gattaccggt ttgaagacat caaggtccta gtcaatacgt ttcaggcgca tcgactcatt
45361 cactgggcac aacaaagcgg cgatgcgcag attttggtag agcggctatt aatagggcag
45421 tttcagcgcg gagagaacct tggtgatgag gctgtccttg ccaaaatcgc cgtagagtgt
45481 agctaccgag agactgccat cgtcgaatac ttgaactctg atgaagacaa tcagcttgtg
45541 caggaacagg aaagggagtc cagggcctgg ggtgtgaccg cagttcctac cttcatcgtc
45601 gggcgaaagc tcatgctcgc aggggccgaa gaccccatgc tttttgccga ggccatcgag
45661 cgagttttgg ttatgggttc ttgataaaga cgcggctgtc tgggctgttc gcagcaatcg
45721 gccggttgct gttgaaaagc tgcccttcaa tcgaccacgt gaccaaagtc cgcattgggt
45781 cgggtgccgt cgcgtgcgca gtgtcaaagc tgacatgacg aatacgtgag aagggccgat
45841 gctcgccgtc cggtcaggct gttgagtcgc ccctgcagga gtcacagcgc tcgtatgtca
45901 cgcgccatcc gagacgtcag tcggcctcat ccagaccgga aca
//
