GenomeNet

Database: RefSeq
Entry: NC_017628
LinkDB: NC_017628
Original site: NC_017628 
LOCUS       NC_017628            5108383 bp    DNA     circular CON 28-AUG-2013
DEFINITION  Escherichia coli IHE3034 chromosome, complete genome.
ACCESSION   NC_017628
VERSION     NC_017628.1  GI:386597751
DBLINK      Project: 162007
            BioProject: PRJNA162007
KEYWORDS    RefSeq.
SOURCE      Escherichia coli IHE3034
  ORGANISM  Escherichia coli IHE3034
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5108383)
  AUTHORS   Moriel,D.G., Bertoldi,I., Spagnuolo,A., Marchi,S., Rosini,R.,
            Nesta,B., Pastorello,I., Corea,V.A., Torricelli,G., Cartocci,E.,
            Savino,S., Scarselli,M., Dobrindt,U., Hacker,J., Tettelin,H.,
            Tallon,L.J., Sullivan,S., Wieler,L.H., Ewers,C., Pickard,D.,
            Dougan,G., Fontana,M.R., Rappuoli,R., Pizza,M. and Serino,L.
  TITLE     Identification of protective and broadly conserved vaccine antigens
            from the genome of extraintestinal pathogenic Escherichia coli
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 107 (20), 9072-9077 (2010)
   PUBMED   20439758
REFERENCE   2  (bases 1 to 5108383)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 5108383)
  AUTHORS   Moriel,D.G., Serino,L., Pizza,M., Rappuoli,R., Dobrindt,U.,
            Hacker,J., Kim,M., Vuong,H., Hostetler,J., Tallon,L.J.,
            Nelson,W.C., Sullivan,S., Daugherty,S.C., Brinkac,L.M.,
            Dodson,R.J., Durkin,A.S., Madupu,R., Harkins,D.M., Shrivastava,S.
            and Tettelin,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-FEB-2010) Novartis Vaccines, Via Florentina, 153100,
            Siena, Italy
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to CP001969.
            Source DNA and bacteria are available from Dr. Ulrich Dobrindt,
            Institut fur Molekulare Infektionsbiologie Universitat, Wuerzburg
            Josef-Schneider-Str. 2/Bau D15 97080 Wuerzburg Germany.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5108383
                     /organism="Escherichia coli IHE3034"
                     /mol_type="genomic DNA"
                     /strain="IHE3034"
                     /db_xref="taxon:714962"
                     /note="K1 strain"
     gene            190..255
                     /gene="thrL"
                     /locus_tag="ECOK1_0001"
                     /db_xref="GeneID:12693254"
     CDS             190..255
                     /gene="thrL"
                     /locus_tag="ECOK1_0001"
                     /note="identified by match to protein family HMM PF08254;
                     match to protein family HMM TIGR02077"
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="YP_006099258.1"
                     /db_xref="GI:386597752"
                     /db_xref="GeneID:12693254"
                     /translation="MKRISTTITTTITITTGNGAG"
     gene            336..2798
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /db_xref="GeneID:12693256"
     CDS             336..2798
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /EC_number="2.7.2.4"
                     /EC_number="1.1.1.3"
                     /note="identified by similarity to SP:P00561; match to
                     protein family HMM PF00696; match to protein family HMM
                     PF00742; match to protein family HMM PF01842; match to
                     protein family HMM PF03447; match to protein family HMM
                     TIGR00657"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartokinase/homoserine dehydrogenase I"
                     /protein_id="YP_006099259.1"
                     /db_xref="GI:386597753"
                     /db_xref="GeneID:12693256"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
                     NHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIK
                     HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAAR
                     VFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKA
                     LLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEG
                     KVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     misc_feature    336..2795
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /note="bifunctional aspartokinase I/homoserine
                     dehydrogenase I; Provisional; Region: thrA; PRK09436"
                     /db_xref="CDD:181856"
     misc_feature    336..1223
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /note="AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK),
                     AK-HSDH; this CD includes the N-terminal catalytic domain
                     of aspartokinase (AK) of the bifunctional enzyme AK -
                     homoserine dehydrogenase (HSDH). These aspartokinases are
                     found in bacteria (E. coli...; Region: AAK_AK-HSDH;
                     cd04257"
                     /db_xref="CDD:239790"
     misc_feature    order(348..350,465..467,714..716,957..959,1092..1094,
                     1131..1133)
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /note="putative catalytic residues [active]"
                     /db_xref="CDD:239790"
     misc_feature    order(348..350,354..362,1017..1022,1029..1034)
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /note="putative nucleotide binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:239790"
     misc_feature    order(447..452,465..467,714..716)
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /note="putative aspartate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:239790"
     misc_feature    1278..1517
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /note="ACT domains of the bifunctional enzyme
                     aspartokinase (AK) - homoserine dehydrogenase (HSDH);
                     Region: ACT_AKi-HSDH-ThrA-like_1; cd04921"
                     /db_xref="CDD:153193"
     misc_feature    order(1302..1310,1317..1322,1332..1334,1341..1346,
                     1365..1367,1371..1391,1395..1400,1404..1406,1410..1412)
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:153193"
     misc_feature    1386..1388
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /note="putative threonine allosteric regulatory site;
                     other site"
                     /db_xref="CDD:153193"
     misc_feature    1521..1718
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /note="ACT domains of the bifunctional enzyme
                     aspartokinase (AK) - homoserine dehydrogenase (HSDH);
                     Region: ACT_AKi-HSDH-ThrA_2; cd04922"
                     /db_xref="CDD:153194"
     misc_feature    1629..1631
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /note="putative threonine allosteric regulatory site;
                     other site"
                     /db_xref="CDD:153194"
     misc_feature    1770..2150
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /note="Homoserine dehydrogenase, NAD binding domain;
                     Region: NAD_binding_3; pfam03447"
                     /db_xref="CDD:251960"
     misc_feature    2175..2768
                     /gene="thrA"
                     /locus_tag="ECOK1_0002"
                     /note="Homoserine dehydrogenase; Region: Homoserine_dh;
                     pfam00742"
                     /db_xref="CDD:250099"
     gene            2800..3732
                     /gene="thrB"
                     /locus_tag="ECOK1_0003"
                     /db_xref="GeneID:12693365"
     CDS             2800..3732
                     /gene="thrB"
                     /locus_tag="ECOK1_0003"
                     /EC_number="2.7.1.39"
                     /note="identified by similarity to SP:P00547; match to
                     protein family HMM PF00288; match to protein family HMM
                     PF08544; match to protein family HMM TIGR00191"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="YP_006099260.1"
                     /db_xref="GI:386597754"
                     /db_xref="GeneID:12693365"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETF
                     SLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACS
                     VVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTA
                     QRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN"
     misc_feature    2803..3723
                     /gene="thrB"
                     /locus_tag="ECOK1_0003"
                     /note="homoserine kinase; Region: thrB; TIGR00191"
                     /db_xref="CDD:129295"
     misc_feature    <2809..3159
                     /gene="thrB"
                     /locus_tag="ECOK1_0003"
                     /note="Protein of unknown function; Region: YhfT;
                     pfam10797"
                     /db_xref="CDD:256168"
     misc_feature    3049..3249
                     /gene="thrB"
                     /locus_tag="ECOK1_0003"
                     /note="GHMP kinases N terminal domain; Region:
                     GHMP_kinases_N; pfam00288"
                     /db_xref="CDD:249743"
     misc_feature    3427..3660
                     /gene="thrB"
                     /locus_tag="ECOK1_0003"
                     /note="GHMP kinases C terminal; Region: GHMP_kinases_C;
                     pfam08544"
                     /db_xref="CDD:254869"
     gene            3733..5019
                     /gene="thrC"
                     /locus_tag="ECOK1_0004"
                     /db_xref="GeneID:12693457"
     CDS             3733..5019
                     /gene="thrC"
                     /locus_tag="ECOK1_0004"
                     /EC_number="4.2.3.1"
                     /note="identified by similarity to SP:P00934; match to
                     protein family HMM PF00291; match to protein family HMM
                     TIGR00260"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="YP_006099261.1"
                     /db_xref="GI:386597755"
                     /db_xref="GeneID:12693457"
                     /translation="MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEID
                     EMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP
                     TLAFKDFGGRFMAQILTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISR
                     LLAQICYYFEAVAQLPQEARNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
                     DTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE
                     TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGE
                     TLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ"
     misc_feature    3733..5016
                     /gene="thrC"
                     /locus_tag="ECOK1_0004"
                     /note="threonine synthase; Validated; Region: PRK09225"
                     /db_xref="CDD:236418"
     misc_feature    3736..5001
                     /gene="thrC"
                     /locus_tag="ECOK1_0004"
                     /note="Threonine synthase catalyzes the final step of
                     threonine biosynthesis. The conversion of
                     O-phosphohomoserine into threonine and inorganic phosphate
                     is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD
                     includes members from higher plants; Region: Thr-synth_2;
                     cd01560"
                     /db_xref="CDD:107203"
     misc_feature    order(4051..4053,4474..4479,4858..4860)
                     /gene="thrC"
                     /locus_tag="ECOK1_0004"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:107203"
     misc_feature    4051..4053
                     /gene="thrC"
                     /locus_tag="ECOK1_0004"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:107203"
     gene            complement(5309..5557)
                     /locus_tag="ECOK1_0005"
                     /db_xref="GeneID:12693459"
     CDS             complement(5309..5557)
                     /locus_tag="ECOK1_0005"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099262.1"
                     /db_xref="GI:386597756"
                     /db_xref="GeneID:12693459"
                     /translation="MPDGNPALIFSDDVCPAPDDDRHDDHCACYGAAMAAVHMGASDC
                     LAIHNVVSTSRGRASDRHPSNSHDYHDRLSVILLTGLA"
     gene            complement(5569..6345)
                     /locus_tag="ECOK1_0006"
                     /db_xref="GeneID:12693461"
     CDS             complement(5569..6345)
                     /locus_tag="ECOK1_0006"
                     /note="identified by similarity to SP:Q8FLD3; match to
                     protein family HMM PF03883"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099263.1"
                     /db_xref="GI:386597757"
                     /db_xref="GeneID:12693461"
                     /translation="MLILISPAKTLDYQSPLTTTRYTLPELLDNAQQLIHEARKLTPP
                     QISSLMRISDKLAGINAARFHDWQPNFTPENARQAILAFKGDVYTGLQAETFSEDDFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
                     AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRF
                     IIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR"
     misc_feature    complement(5575..6345)
                     /locus_tag="ECOK1_0006"
                     /note="hypothetical protein; Validated; Region: PRK02101"
                     /db_xref="CDD:234999"
     gene            complement(6415..7845)
                     /gene="agcS"
                     /locus_tag="ECOK1_0007"
                     /db_xref="GeneID:12693489"
     CDS             complement(6415..7845)
                     /gene="agcS"
                     /locus_tag="ECOK1_0007"
                     /note="identified by match to protein family HMM PF01235;
                     match to protein family HMM TIGR00835"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid carrier protein"
                     /protein_id="YP_006099264.1"
                     /db_xref="GI:386597758"
                     /db_xref="GeneID:12693489"
                     /translation="MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFG
                     KSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIG
                     MATSFAECSLAQLYKERDANGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYAIIFSG
                     VQANAVARALSFSFDFPPLVTGIILAVFALLAITRGLHGVARLMQGFVPLMAIIWVLT
                     CLVICVMNIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMG
                     STPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQ
                     LIQKAMRVLMGSWGAEFVTLVVILFAFSSIVTNYIYAENNLFFLRLNNPKAIWCLRIC
                     TFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVR
                     PVFDPLRYPEIGRQLSPDAWDDVSQE"
     misc_feature    complement(6472..7704)
                     /gene="agcS"
                     /locus_tag="ECOK1_0007"
                     /note="Sodium:alanine symporter family; Region:
                     Na_Ala_symp; pfam01235"
                     /db_xref="CDD:250465"
     gene            8124..9077
                     /gene="tal"
                     /locus_tag="ECOK1_0008"
                     /db_xref="GeneID:12693491"
     CDS             8124..9077
                     /gene="tal"
                     /locus_tag="ECOK1_0008"
                     /EC_number="2.2.1.2"
                     /note="identified by match to protein family HMM PF00923;
                     match to protein family HMM TIGR00874"
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="YP_006099265.1"
                     /db_xref="GI:386597759"
                     /db_xref="GeneID:12693491"
                     /translation="MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGY
                     ETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARI
                     TESEFLWQHNQDPMAVDKLAEGIRKFAVDQEKLEKMIGDLL"
     misc_feature    8124..9074
                     /gene="tal"
                     /locus_tag="ECOK1_0008"
                     /note="transaldolase-like protein; Provisional; Region:
                     PTZ00411"
                     /db_xref="CDD:240406"
     misc_feature    8133..9062
                     /gene="tal"
                     /locus_tag="ECOK1_0008"
                     /note="Transaldolases including both TalA and TalB;
                     Region: Transaldolase_TalAB; cd00957"
                     /db_xref="CDD:188644"
     misc_feature    order(8172..8174,8220..8222,8226..8231,8403..8405,
                     8409..8411,8517..8519,8583..8585,8589..8591,8649..8651,
                     8664..8666)
                     /gene="tal"
                     /locus_tag="ECOK1_0008"
                     /note="active site"
                     /db_xref="CDD:188644"
     misc_feature    order(8433..8435,8958..8960,8967..8969,8979..8984,
                     9000..9002,9009..9011,9021..9023)
                     /gene="tal"
                     /locus_tag="ECOK1_0008"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:188644"
     misc_feature    8517..8519
                     /gene="tal"
                     /locus_tag="ECOK1_0008"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188644"
     gene            9192..9779
                     /gene="mog"
                     /locus_tag="ECOK1_0009"
                     /db_xref="GeneID:12693252"
     CDS             9192..9779
                     /gene="mog"
                     /locus_tag="ECOK1_0009"
                     /note="identified by similarity to SP:P0AF03; match to
                     protein family HMM PF00994; match to protein family HMM
                     TIGR00177"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin biosynthesis protein Mog"
                     /protein_id="YP_006099266.1"
                     /db_xref="GI:386597760"
                     /db_xref="GeneID:12693252"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQ
                     MRQISLHFVLTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFA
                     SVPYCIQLLEGPYVETAPEVVAAFRPKSARREVSE"
     misc_feature    9201..9698
                     /gene="mog"
                     /locus_tag="ECOK1_0009"
                     /note="MogA_MoaB family. Members of this family are
                     involved in biosynthesis of the molybdenum cofactor (MoCF)
                     an essential cofactor of a diverse group of redox enzymes.
                     MoCF biosynthesis is an evolutionarily conserved pathway
                     present in eubacteria, archaea; Region: MogA_MoaB;
                     cd00886"
                     /db_xref="CDD:238451"
     misc_feature    order(9414..9422,9510..9512,9588..9593,9603..9605,
                     9612..9614)
                     /gene="mog"
                     /locus_tag="ECOK1_0009"
                     /note="MPT binding site; other site"
                     /db_xref="CDD:238451"
     misc_feature    order(9420..9422,9426..9431,9435..9437,9447..9449,
                     9471..9479,9492..9494,9501..9506,9534..9536,9543..9545,
                     9696..9698)
                     /gene="mog"
                     /locus_tag="ECOK1_0009"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238451"
     gene            complement(9984..10550)
                     /locus_tag="ECOK1_0010"
                     /db_xref="GeneID:12688578"
     CDS             complement(9984..10550)
                     /locus_tag="ECOK1_0010"
                     /note="identified by match to protein family HMM PF01184"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein, GPR1/FUN34/yaaH family"
                     /protein_id="YP_006099267.1"
                     /db_xref="GI:386597761"
                     /db_xref="GeneID:12688578"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVY
                     LGLWGIFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
                     GASAIYLAMGEVLNEQFGRTVLPIGESH"
     misc_feature    complement(9987..10550)
                     /locus_tag="ECOK1_0010"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10659"
                     /db_xref="CDD:182625"
     gene            complement(10699..11412)
                     /locus_tag="ECOK1_0011"
                     /db_xref="GeneID:12688579"
     CDS             complement(10699..11412)
                     /locus_tag="ECOK1_0011"
                     /note="identified by match to protein family HMM PF03667"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099268.1"
                     /db_xref="GI:386597762"
                     /db_xref="GeneID:12688579"
                     /translation="MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLM
                     RNELFKSMEGHPERHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKL
                     KADKEMSTFEIEQQLLEQFLRNTWKKMDEEHKQEFLHAVDARVNELEELLPLLMKDKL
                     LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSAYRVT
                     IPAVLQIACLRRMVSATQV"
     misc_feature    complement(10702..11412)
                     /locus_tag="ECOK1_0011"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10236"
                     /db_xref="CDD:182323"
     misc_feature    complement(11296..11400)
                     /locus_tag="ECOK1_0011"
                     /note="Domain of unknown function (DUF3944); Region:
                     DUF3944; pfam13099"
                     /db_xref="CDD:257500"
     misc_feature    complement(10702..11298)
                     /locus_tag="ECOK1_0011"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4735"
                     /db_xref="CDD:227078"
     gene            complement(11438..11842)
                     /locus_tag="ECOK1_0012"
                     /db_xref="GeneID:12688580"
     CDS             complement(11438..11842)
                     /locus_tag="ECOK1_0012"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099269.1"
                     /db_xref="GI:386597763"
                     /db_xref="GeneID:12688580"
                     /translation="MKSVITISASLAISLMLCCTAQANDHKILGVIAMPRNETNDLAL
                     KLPVCRIVKRIQLSADHGDLQLSGASIYFKATRSASQTLNIPSEIKEEQTTDWININS
                     DNDNKRCVSKITFSGHTVNSSDMATLKIIGDD"
     misc_feature    complement(11441..11842)
                     /locus_tag="ECOK1_0012"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10154"
                     /db_xref="CDD:182272"
     gene            12214..14130
                     /gene="dnaK"
                     /locus_tag="ECOK1_0013"
                     /db_xref="GeneID:12688581"
     CDS             12214..14130
                     /gene="dnaK"
                     /locus_tag="ECOK1_0013"
                     /note="identified by match to protein family HMM PF00012;
                     match to protein family HMM TIGR02350"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone protein DnaK"
                     /protein_id="YP_006099270.1"
                     /db_xref="GI:386597764"
                     /db_xref="GeneID:12688581"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAW
                     VEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     DDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAAD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDD
                     DVVDAEFEEVKDKK"
     misc_feature    12214..14127
                     /gene="dnaK"
                     /locus_tag="ECOK1_0013"
                     /note="molecular chaperone DnaK; Provisional; Region:
                     dnaK; PRK00290"
                     /db_xref="CDD:234715"
     misc_feature    12214..13359
                     /gene="dnaK"
                     /locus_tag="ECOK1_0013"
                     /note="Nucleotide-binding domain of human HSPA9,
                     Escherichia coli DnaK, and similar proteins; Region:
                     HSPA9-like_NBD; cd11733"
                     /db_xref="CDD:212683"
     misc_feature    order(12241..12252,12421..12423,12724..12726,12799..12804,
                     12808..12810,12898..12900,13012..13014,13021..13023,
                     13033..13035,13234..13242,13246..13248)
                     /gene="dnaK"
                     /locus_tag="ECOK1_0013"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212683"
     misc_feature    order(12295..12297,12304..12306,12358..12360,12370..12372,
                     12379..12384,12388..12393,12598..12609,12982..12984,
                     12991..12996,13003..13005,13057..13059,13063..13068)
                     /gene="dnaK"
                     /locus_tag="ECOK1_0013"
                     /note="NEF interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:212683"
     misc_feature    order(12655..12660,12664..12669,12712..12717,12721..12723,
                     12859..12870)
                     /gene="dnaK"
                     /locus_tag="ECOK1_0013"
                     /note="SBD interface [polypeptide binding]; other site"
                     /db_xref="CDD:212683"
     gene            14219..15349
                     /gene="dnaJ"
                     /locus_tag="ECOK1_0014"
                     /db_xref="GeneID:12688582"
     CDS             14219..15349
                     /gene="dnaJ"
                     /locus_tag="ECOK1_0014"
                     /note="identified by match to protein family HMM PF00226;
                     match to protein family HMM PF00684; match to protein
                     family HMM PF01556; match to protein family HMM TIGR02349"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone protein DnaJ"
                     /protein_id="YP_006099271.1"
                     /db_xref="GI:386597765"
                     /db_xref="GeneID:12688582"
                     /translation="MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAE
                     AKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIF
                     GGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
                     CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPA
                     GVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAAL
                     GGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLN
                     EKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR"
     misc_feature    14219..15334
                     /gene="dnaJ"
                     /locus_tag="ECOK1_0014"
                     /note="chaperone protein DnaJ; Provisional; Region:
                     PRK10767"
                     /db_xref="CDD:236757"
     misc_feature    14231..14395
                     /gene="dnaJ"
                     /locus_tag="ECOK1_0014"
                     /note="DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock
                     protein 40) proteins are highly conserved and play crucial
                     roles in protein translation, folding, unfolding,
                     translocation, and degradation. They act primarily by
                     stimulating the ATPase activity of Hsp70s; Region: DnaJ;
                     cd06257"
                     /db_xref="CDD:99751"
     misc_feature    order(14315..14323,14348..14350,14357..14362,14369..14374)
                     /gene="dnaJ"
                     /locus_tag="ECOK1_0014"
                     /note="HSP70 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99751"
     misc_feature    14561..15217
                     /gene="dnaJ"
                     /locus_tag="ECOK1_0014"
                     /note="C-terminal substrate binding domain of DnaJ and
                     HSP40; Region: DnaJ_C; cd10747"
                     /db_xref="CDD:199909"
     misc_feature    order(14573..14575,14618..14635,14843..14845,14915..14917)
                     /gene="dnaJ"
                     /locus_tag="ECOK1_0014"
                     /note="substrate binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:199909"
     misc_feature    14648..14830
                     /gene="dnaJ"
                     /locus_tag="ECOK1_0014"
                     /note="Zinc finger domain of DnaJ and HSP40; Region:
                     DnaJ_zf; cd10719"
                     /db_xref="CDD:199908"
     misc_feature    order(14648..14650,14657..14659,14699..14701,14708..14710,
                     14765..14767,14774..14776,14807..14809,14816..14818)
                     /gene="dnaJ"
                     /locus_tag="ECOK1_0014"
                     /note="Zn binding sites [ion binding]; other site"
                     /db_xref="CDD:199908"
     misc_feature    order(15029..15034,15041..15046,15104..15115,15203..15217)
                     /gene="dnaJ"
                     /locus_tag="ECOK1_0014"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:199909"
     gene            16218..16979
                     /locus_tag="ECOK1_0015"
                     /db_xref="GeneID:12688583"
     CDS             16218..16979
                     /locus_tag="ECOK1_0015"
                     /note="identified by similarity to GB:AAV76071.1; match to
                     protein family HMM PF07135"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099272.1"
                     /db_xref="GI:386597766"
                     /db_xref="GeneID:12688583"
                     /translation="MSAKRRLLIACALTTIFYHLPAYSSLEYKGSFGSINAGYADWNS
                     GFINTHRGEVWKVTADFGVNFKEAEFYSFYESNVLNHAVAGRNHTVSAMTHVRLFDSN
                     MTFFGKIYGQWDNSWGDDLDMFYGLGYLGWNGSWGFFKPYIGLHNQSGDYVSAKYGQT
                     NGWNGYVVGWTAVLPFTLFDEKFVLSNWNEIELDRNDAYAEQQFGRNGLNGGLTVAWK
                     FYPRWKASVTWRYFDNKLGYDGFGDQMIYMLGYDF"
     misc_feature    16326..16976
                     /locus_tag="ECOK1_0015"
                     /note="Nucleoside-specific channel-forming protein, Tsx;
                     Region: Channel_Tsx; pfam03502"
                     /db_xref="CDD:252004"
     gene            16999..18492
                     /locus_tag="ECOK1_0016"
                     /db_xref="GeneID:12688584"
     CDS             16999..18492
                     /locus_tag="ECOK1_0016"
                     /EC_number="3.1.6.-"
                     /note="identified by match to protein family HMM PF00884"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="YP_006099273.1"
                     /db_xref="GI:386597767"
                     /db_xref="GeneID:12688584"
                     /translation="MQKTLMASLIGLAVCTGNAFNPVVAAETKQPNLVIIMADDLGYG
                     DLATYGHQIVKTPNIDRLAQEGVKFTDYYAPAPLSSPSRAGLLTGRMPFRTGIRSWIP
                     TGKDVALGRNELTIANLLKAQGYDTAMMGKLHLNAGGDRTDQPQAKDMGFDYSLVNTA
                     GFVTDATLDNAKERPRYGMVYPTGWLRNGQPTPRADKMSGEYVSSEVVNWLDNKKDSK
                     PFFLYVAFTEVHSPLASPKKYLDMYSQYMSAYQKQHPDLFYGDWADKPWRGVGEYYAN
                     ISYLDAQVGKVLDKIKAMGEEDNTIVIFTSDNGPVTREARKVYELNLAGETDGLRGRK
                     DNLWEGGIRVPAIIKYGKHLPQGMVSDTPVYGLDWMPTLAKMMNFKLPTDRTFDGESL
                     VPVLEQKALKREKPLIFGIDMPFQDDPTDEWAIRDGDWKMIIDRNNKPKYLYNLKSDR
                     YETLNLIGKKPDIEKQMYGKFLKYKTDIDNDSLMKARGDKPEAVTWG"
     misc_feature    17077..18366
                     /locus_tag="ECOK1_0016"
                     /note="Arylsulfatase A and related enzymes [Inorganic ion
                     transport and metabolism]; Region: AslA; COG3119"
                     /db_xref="CDD:225661"
     misc_feature    17089..18132
                     /locus_tag="ECOK1_0016"
                     /note="Sulfatase; Region: Sulfatase; pfam00884"
                     /db_xref="CDD:250201"
     gene            18621..19880
                     /locus_tag="ECOK1_0017"
                     /db_xref="GeneID:12688585"
     CDS             18621..19880
                     /locus_tag="ECOK1_0017"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099274.1"
                     /db_xref="GI:386597768"
                     /db_xref="GeneID:12688585"
                     /translation="MFTNVNVDCCKTPGCKNLGLLNSQDYVAQGKNILCRECGYLFPV
                     ISEQSLNIYRNIVNHSWRGLICQCSTCGGTSLKKYGYSAQGQRRMYCHHCEKTFITLE
                     HVITTPRGALLALMIEQGEALADIRKSLLLNSTGLSRELLKLAREANYKESRQCFPAS
                     DITLSTRAFRVKYNGSNNSLYALVTAEEQSGRVVAISTNYSPSAVEQHYQYTSNYEER
                     MSPGTLAHHVQRKELLTMRRDTLFDIDYGPAVLHQNDPGMLVKPVLPAYRHFELVRIL
                     TDEHSNNVQHYLDHECFILGGCLMANLQHIPQGRCHISFVKERGVAPATIDFPPRLFL
                     SGGVRNNVWRAFSNRNYSMAVCNLTGSKKVREMRHATLNSATRFIHFVENHPFLISLN
                     RMSPANVVSTLDILKHLWNKKLEHGTI"
     gene            20115..21281
                     /gene="nhaA"
                     /locus_tag="ECOK1_0018"
                     /db_xref="GeneID:12688586"
     CDS             20115..21281
                     /gene="nhaA"
                     /locus_tag="ECOK1_0018"
                     /note="identified by similarity to SP:P13738; match to
                     protein family HMM PF06965; match to protein family HMM
                     TIGR00773"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="YP_006099275.1"
                     /db_xref="GI:386597769"
                     /db_xref="GeneID:12688586"
                     /translation="MKHLHRFFSSDASGGIILIIAAVLAMIMANSGATSGWYHDFLET
                     PVQLRVGTLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLVVLNLCGVRRTGVYILVGVVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTLEGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGIL
                     CGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV"
     misc_feature    20115..21278
                     /gene="nhaA"
                     /locus_tag="ECOK1_0018"
                     /note="pH-dependent sodium/proton antiporter; Reviewed;
                     Region: nhaA; PRK09561"
                     /db_xref="CDD:181955"
     gene            21341..22246
                     /gene="nhaR"
                     /locus_tag="ECOK1_0019"
                     /db_xref="GeneID:12688587"
     CDS             21341..22246
                     /gene="nhaR"
                     /locus_tag="ECOK1_0019"
                     /note="identified by similarity to SP:P0A9G2; match to
                     protein family HMM PF00126; match to protein family HMM
                     PF03466"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator protein NhaR"
                     /protein_id="YP_006099276.1"
                     /db_xref="GI:386597770"
                     /db_xref="GeneID:12688587"
                     /translation="MSMSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRAL
                     EERLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVA
                     DALSKRLVSSVLDAAVVEDEQIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQE
                     GLFSMKIGECGVSFWCTNPLPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNV
                     EILGEFDDAALMKAFGATHNAIFVAPSLYANDFYNDDSVVEIGRVENVMEEYHAIFAE
                     RMIQHPAVQRICNTDYSALFTPASK"
     misc_feature    21347..22234
                     /gene="nhaR"
                     /locus_tag="ECOK1_0019"
                     /note="transcriptional activator NhaR; Provisional;
                     Region: nhaR; PRK11062"
                     /db_xref="CDD:182938"
     misc_feature    21365..21541
                     /gene="nhaR"
                     /locus_tag="ECOK1_0019"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    21626..22228
                     /gene="nhaR"
                     /locus_tag="ECOK1_0019"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional activator of the nhaA gene,
                     encoding Na+/H+ antiporter, contains the type 2
                     periplasmic binding fold; Region: PBP2_NhaR; cd08429"
                     /db_xref="CDD:176120"
     misc_feature    order(21671..21676,21680..21685,21692..21694,21704..21706,
                     21710..21730,22001..22018,22034..22039,22043..22048)
                     /gene="nhaR"
                     /locus_tag="ECOK1_0019"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176120"
     gene            complement(22342..22605)
                     /gene="rpsT"
                     /locus_tag="ECOK1_0020"
                     /db_xref="GeneID:12688588"
     CDS             complement(22342..22605)
                     /gene="rpsT"
                     /locus_tag="ECOK1_0020"
                     /note="identified by match to protein family HMM PF01649;
                     match to protein family HMM TIGR00029"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="YP_006099277.1"
                     /db_xref="GI:386597771"
                     /db_xref="GeneID:12688588"
                     /translation="MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
     misc_feature    complement(22345..22605)
                     /gene="rpsT"
                     /locus_tag="ECOK1_0020"
                     /note="30S ribosomal protein S20; Reviewed; Region: rpsT;
                     PRK00239"
                     /db_xref="CDD:178943"
     gene            22934..23875
                     /gene="ribF"
                     /locus_tag="ECOK1_0021"
                     /db_xref="GeneID:12688589"
     CDS             22934..23875
                     /gene="ribF"
                     /locus_tag="ECOK1_0021"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /note="identified by match to protein family HMM PF01687;
                     match to protein family HMM PF06574; match to protein
                     family HMM TIGR00083"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="YP_006099278.1"
                     /db_xref="GI:386597772"
                     /db_xref="GeneID:12688589"
                     /translation="MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGR
                     KRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAAL
                     TAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
                     GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQV
                     SPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVL
                     RKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA"
     misc_feature    22937..23860
                     /gene="ribF"
                     /locus_tag="ECOK1_0021"
                     /note="bifunctional riboflavin kinase/FMN
                     adenylyltransferase; Reviewed; Region: PRK05627"
                     /db_xref="CDD:235536"
     misc_feature    22985..23527
                     /gene="ribF"
                     /locus_tag="ECOK1_0021"
                     /note="FAD synthetase, N-terminal domain of the
                     bifunctional enzyme; Region: FAD_synthetase_N; cd02064"
                     /db_xref="CDD:185679"
     misc_feature    order(23000..23011,23018..23020,23027..23029,23309..23311,
                     23399..23401,23423..23431)
                     /gene="ribF"
                     /locus_tag="ECOK1_0021"
                     /note="active site"
                     /db_xref="CDD:185679"
     misc_feature    23483..23854
                     /gene="ribF"
                     /locus_tag="ECOK1_0021"
                     /note="Riboflavin kinase; Region: Flavokinase; smart00904"
                     /db_xref="CDD:214901"
     gene            23918..26734
                     /gene="ileS"
                     /locus_tag="ECOK1_0022"
                     /db_xref="GeneID:12688590"
     CDS             23918..26734
                     /gene="ileS"
                     /locus_tag="ECOK1_0022"
                     /EC_number="6.1.1.5"
                     /note="identified by match to protein family HMM PF00133;
                     match to protein family HMM PF06827; match to protein
                     family HMM PF08264; match to protein family HMM PF09334;
                     match to protein family HMM TIGR00392"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucyl-tRNA synthetase"
                     /protein_id="YP_006099279.1"
                     /db_xref="GI:386597773"
                     /db_xref="GeneID:12688590"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIIKSKGLSGYDSPYVPGWDCHGLPI
                     ELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFLAVD
                     QDALKTKFGVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD
                     LVESVMQRIGVSDYTILGTVKGAELELLRFTHPFMDFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVIALLQEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAW
                     WDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQH
                     RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADI
                     LRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMV
                     VLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKA
                     DSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGL
                     ADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELAAKLTALG
                     DELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKV
                     AEHAEICGRCVSNVAGDGEKRKFA"
     misc_feature    23918..26707
                     /gene="ileS"
                     /locus_tag="ECOK1_0022"
                     /note="isoleucyl-tRNA synthetase; Reviewed; Region: ileS;
                     PRK05743"
                     /db_xref="CDD:235588"
     misc_feature    24062..25837
                     /gene="ileS"
                     /locus_tag="ECOK1_0022"
                     /note="catalytic core domain of isoleucyl-tRNA
                     synthetases; Region: IleRS_core; cd00818"
                     /db_xref="CDD:173909"
     misc_feature    order(24086..24094,24110..24112,24116..24121,24128..24130,
                     25268..25270,25517..25519,25526..25528,25598..25612,
                     25616..25618,25622..25624,25691..25705,25715..25732,
                     25826..25828)
                     /gene="ileS"
                     /locus_tag="ECOK1_0022"
                     /note="active site"
                     /db_xref="CDD:173909"
     misc_feature    24110..24121
                     /gene="ileS"
                     /locus_tag="ECOK1_0022"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173909"
     misc_feature    25721..25735
                     /gene="ileS"
                     /locus_tag="ECOK1_0022"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:173909"
     misc_feature    25835..26377
                     /gene="ileS"
                     /locus_tag="ECOK1_0022"
                     /note="Anticodon-binding domain of bacterial and
                     eukaryotic mitochondrial isoleucyl tRNA synthetases;
                     Region: Anticodon_Ia_Ile_BEm; cd07960"
                     /db_xref="CDD:153414"
     misc_feature    order(25844..25846,25856..25858,25865..25867,25877..25879,
                     25886..25888,25895..25900,26042..26044,26051..26056,
                     26063..26068,26075..26077,26090..26092,26102..26104,
                     26111..26113,26366..26368,26375..26377)
                     /gene="ileS"
                     /locus_tag="ECOK1_0022"
                     /note="tRNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:153414"
     misc_feature    order(25886..25888,25895..25897)
                     /gene="ileS"
                     /locus_tag="ECOK1_0022"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:153414"
     misc_feature    26609..26698
                     /gene="ileS"
                     /locus_tag="ECOK1_0022"
                     /note="Zinc finger found in FPG and IleRS; Region:
                     zf-FPG_IleRS; pfam06827"
                     /db_xref="CDD:253933"
     gene            26734..27228
                     /gene="lspA"
                     /locus_tag="ECOK1_0023"
                     /db_xref="GeneID:12688591"
     CDS             26734..27228
                     /gene="lspA"
                     /locus_tag="ECOK1_0023"
                     /EC_number="3.4.23.36"
                     /note="identified by match to protein family HMM PF01252;
                     match to protein family HMM TIGR00077"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="YP_006099280.1"
                     /db_xref="GI:386597774"
                     /db_xref="GeneID:12688591"
                     /translation="MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFP
                     SLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSK
                     AKKQ"
     misc_feature    26737..27213
                     /gene="lspA"
                     /locus_tag="ECOK1_0023"
                     /note="lipoprotein signal peptidase; Reviewed; Region:
                     lspA; PRK00376"
                     /db_xref="CDD:234739"
     gene            27336..27785
                     /gene="fkpB"
                     /locus_tag="ECOK1_0024"
                     /db_xref="GeneID:12688592"
     CDS             27336..27785
                     /gene="fkpB"
                     /locus_tag="ECOK1_0024"
                     /EC_number="5.2.1.8"
                     /note="identified by similarity to SP:P22563; match to
                     protein family HMM PF00254"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type 16 kDa peptidyl-prolyl cis-trans
                     isomerase"
                     /protein_id="YP_006099281.1"
                     /db_xref="GI:386597775"
                     /db_xref="GeneID:12688592"
                     /translation="MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASL
                     SEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA"
     misc_feature    27336..27782
                     /gene="fkpB"
                     /locus_tag="ECOK1_0024"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerase;
                     Provisional; Region: PRK15095"
                     /db_xref="CDD:237908"
     misc_feature    27348..27779
                     /gene="fkpB"
                     /locus_tag="ECOK1_0024"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerases 2
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: SlpA; COG1047"
                     /db_xref="CDD:223976"
     gene            27787..28737
                     /gene="ispH"
                     /locus_tag="ECOK1_0025"
                     /db_xref="GeneID:12688593"
     CDS             27787..28737
                     /gene="ispH"
                     /locus_tag="ECOK1_0025"
                     /EC_number="1.17.1.2"
                     /note="identified by similarity to SP:P62623; match to
                     protein family HMM PF02401; match to protein family HMM
                     TIGR00216"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="YP_006099282.1"
                     /db_xref="GI:386597776"
                     /db_xref="GeneID:12688593"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVL
                     VVGSKNSSNSNRLAELAQRMGKRAFLIDDATDIQEEWVKEAKCVGVTAGASAPDILVQ
                     NVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD"
     misc_feature    27793..28632
                     /gene="ispH"
                     /locus_tag="ECOK1_0025"
                     /note="4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
                     Region: lytB_ispH; cd13944"
                     /db_xref="CDD:260116"
     misc_feature    order(27820..27822,28072..28074,28375..28377)
                     /gene="ispH"
                     /locus_tag="ECOK1_0025"
                     /note="Fe-S cluster binding site [ion binding]; other
                     site"
                     /db_xref="CDD:260116"
     misc_feature    order(27829..27831,27904..27909,28003..28008,28156..28158,
                     28162..28164,28285..28290,28456..28467,28591..28593)
                     /gene="ispH"
                     /locus_tag="ECOK1_0025"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:260116"
     misc_feature    order(28156..28158,28162..28164,28459..28461,28465..28467)
                     /gene="ispH"
                     /locus_tag="ECOK1_0025"
                     /note="catalytic site [active]"
                     /db_xref="CDD:260116"
     gene            28803..29717
                     /gene="rihC"
                     /locus_tag="ECOK1_0026"
                     /db_xref="GeneID:12688594"
     CDS             28803..29717
                     /gene="rihC"
                     /locus_tag="ECOK1_0026"
                     /EC_number="3.2.-.-"
                     /note="identified by similarity to SP:P0C0W2; match to
                     protein family HMM PF01156"
                     /codon_start=1
                     /transl_table=11
                     /product="nonspecific ribonucleoside hydrolase RihC"
                     /protein_id="YP_006099283.1"
                     /db_xref="GI:386597777"
                     /db_xref="GeneID:12688594"
                     /translation="MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEK
                     TTRNALQLLHFWNVDIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRQPLGIP
                     AFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTP
                     NAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALF
                     SHYRSGSMQSGLRMHDLCAIAWLVRPELFTLKPCFVAVETQGEFTSGTTVVDIDGCLG
                     KPANVQVALDLDVKGFQQWVAEVLALAL"
     misc_feature    28812..29702
                     /gene="rihC"
                     /locus_tag="ECOK1_0026"
                     /note="nuc_hydro_IU_UC_XIUA: inosine-uridine preferring,
                     xanthosine-inosine-uridine-adenosine-preferring and,
                     uridine-cytidine preferring nucleoside hydrolases.
                     Nucleoside hydrolases cleave the N-glycosidic bond in
                     nucleosides generating ribose and the...; Region:
                     nuc_hydro_IU_UC_XIUA; cd02651"
                     /db_xref="CDD:239117"
     misc_feature    order(28830..28832,28842..28847,28917..28919,29040..29042,
                     29169..29171,29271..29273,29289..29291,29295..29297,
                     29502..29504)
                     /gene="rihC"
                     /locus_tag="ECOK1_0026"
                     /note="active site"
                     /db_xref="CDD:239117"
     misc_feature    order(29010..29012,29202..29204,29325..29327,29571..29573,
                     29577..29582,29589..29591)
                     /gene="rihC"
                     /locus_tag="ECOK1_0026"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239117"
     gene            29740..30105
                     /locus_tag="ECOK1_0027"
                     /db_xref="GeneID:12688595"
     CDS             29740..30105
                     /locus_tag="ECOK1_0027"
                     /note="identified by match to protein family HMM PF05656"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099284.1"
                     /db_xref="GI:386597778"
                     /db_xref="GeneID:12688595"
                     /translation="MTYGEAYLEGWKNIFNYEGVSNRFEFWSFMIGSGVICLLPLLCW
                     WLAVTINNDYGVFIFFALPASFILTLIFAIPAIALAVRRMHDIGYSGWWVTIVVLIPV
                     TGVILLILCCLPSKSQDQA"
     misc_feature    29776..30096
                     /locus_tag="ECOK1_0027"
                     /note="Protein of unknown function (DUF805); Region:
                     DUF805; pfam05656"
                     /db_xref="CDD:253305"
     gene            30266..31087
                     /gene="dapB"
                     /locus_tag="ECOK1_0028"
                     /db_xref="GeneID:12688596"
     CDS             30266..31087
                     /gene="dapB"
                     /locus_tag="ECOK1_0028"
                     /EC_number="1.3.1.26"
                     /note="identified by similarity to SP:P04036; match to
                     protein family HMM PF01113; match to protein family HMM
                     PF05173; match to protein family HMM TIGR00036"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="YP_006099285.1"
                     /db_xref="GI:386597779"
                     /db_xref="GeneID:12688596"
                     /translation="MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSL
                     LGSDAGELAGAGKTGVTVQSSLDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIG
                     TTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVG
                     EHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL"
     misc_feature    30281..31075
                     /gene="dapB"
                     /locus_tag="ECOK1_0028"
                     /note="Dihydrodipicolinate reductase [Amino acid transport
                     and metabolism]; Region: DapB; COG0289"
                     /db_xref="CDD:223366"
     misc_feature    30281..30652
                     /gene="dapB"
                     /locus_tag="ECOK1_0028"
                     /note="Dihydrodipicolinate reductase, N-terminus; Region:
                     DapB_N; pfam01113"
                     /db_xref="CDD:250369"
     misc_feature    30659..31069
                     /gene="dapB"
                     /locus_tag="ECOK1_0028"
                     /note="Dihydrodipicolinate reductase, C-terminus; Region:
                     DapB_C; pfam05173"
                     /db_xref="CDD:253059"
     gene            complement(31099..31281)
                     /locus_tag="ECOK1_0029"
                     /db_xref="GeneID:12688597"
     CDS             complement(31099..31281)
                     /locus_tag="ECOK1_0029"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099286.1"
                     /db_xref="GI:386597780"
                     /db_xref="GeneID:12688597"
                     /translation="MSRKKWTKWSKFTLKQQKQNTKHVIFSICIRFKSITLKIKGPKI
                     KALYIQRIKCVVFASP"
     gene            31543..32691
                     /gene="carA"
                     /locus_tag="ECOK1_0030"
                     /db_xref="GeneID:12688598"
     CDS             31543..32691
                     /gene="carA"
                     /locus_tag="ECOK1_0030"
                     /EC_number="6.3.5.5"
                     /note="identified by similarity to SP:P0A6F1; match to
                     protein family HMM PF00117; match to protein family HMM
                     PF00988; match to protein family HMM TIGR01368"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase small subunit"
                     /protein_id="YP_006099287.1"
                     /db_xref="GI:386597781"
                     /db_xref="GeneID:12688598"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
                     EVTTAEPYSWTQGSWTLTGGLPEAKKEDELPYHVVAYDFGAKRNILRMLVDRGCRLTI
                     VPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLA
                     LASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIALIEQYRKTAK"
     misc_feature    31543..32664
                     /gene="carA"
                     /locus_tag="ECOK1_0030"
                     /note="carbamoyl phosphate synthase small subunit;
                     Reviewed; Region: PRK12564"
                     /db_xref="CDD:237139"
     misc_feature    31549..31938
                     /gene="carA"
                     /locus_tag="ECOK1_0030"
                     /note="Carbamoyl-phosphate synthase small chain, CPSase
                     domain; Region: CPSase_sm_chain; smart01097"
                     /db_xref="CDD:198165"
     misc_feature    32122..32655
                     /gene="carA"
                     /locus_tag="ECOK1_0030"
                     /note="Small chain of the glutamine-dependent form of
                     carbamoyl phosphate synthase, CPSase II; Region:
                     GATase1_CPSase; cd01744"
                     /db_xref="CDD:153215"
     misc_feature    order(32347..32349,32599..32601,32605..32607)
                     /gene="carA"
                     /locus_tag="ECOK1_0030"
                     /note="catalytic site [active]"
                     /db_xref="CDD:153215"
     misc_feature    order(32422..32424,32428..32430,32449..32451,32455..32457,
                     32536..32538,32614..32619,32623..32628)
                     /gene="carA"
                     /locus_tag="ECOK1_0030"
                     /note="subunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:153215"
     gene            32709..35930
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /db_xref="GeneID:12688599"
     CDS             32709..35930
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /EC_number="6.3.5.5"
                     /note="identified by similarity to SP:P00968; match to
                     protein family HMM PF00289; match to protein family HMM
                     PF02142; match to protein family HMM PF02786; match to
                     protein family HMM PF02787; match to protein family HMM
                     TIGR01369"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="YP_006099288.1"
                     /db_xref="GI:386597782"
                     /db_xref="GeneID:12688599"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHSMEEALAVAA
                     EVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLHAEFLRQLKRKGFADARLAKLAGV
                     REAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLG
                     GGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLE
                     DVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAV
                     ERLKLKQPANATVTTIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQT
                     AVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPA
                     YTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKA
                     TGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRST
                     GEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELD
                     ATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIR
                     RSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK"
     misc_feature    32709..35915
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /note="carbamoyl phosphate synthase large subunit;
                     Reviewed; Region: carB; PRK05294"
                     /db_xref="CDD:235393"
     misc_feature    32727..33074
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /note="Carbamoyl-phosphate synthase L chain, N-terminal
                     domain; Region: CPSase_L_chain; pfam00289"
                     /db_xref="CDD:249744"
     misc_feature    33090..33713
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /note="Carbamoyl-phosphate synthase L chain, ATP binding
                     domain; Region: CPSase_L_D2; pfam02786"
                     /db_xref="CDD:190425"
     misc_feature    33978..34349
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /note="Carbamoyl-phosphate synthetase large chain,
                     oligomerisation domain; Region: CPSase_L_D3; smart01096"
                     /db_xref="CDD:198164"
     misc_feature    34386..34712
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /note="Carbamoyl-phosphate synthase L chain, N-terminal
                     domain; Region: CPSase_L_chain; pfam00289"
                     /db_xref="CDD:249744"
     misc_feature    34728..35336
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /note="ATP-grasp domain; Region: ATP-grasp_4; cl17255"
                     /db_xref="CDD:266590"
     misc_feature    35535..35864
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /note="Methylglyoxal synthase-like domain from type II
                     glutamine-dependent carbamoyl phosphate synthetase (CSP).
                     CSP, a CarA and CarB heterodimer, catalyzes the production
                     of carbamoyl phosphate which is subsequently employed in
                     the metabolic pathways...; Region: MGS_CPS_II; cd01424"
                     /db_xref="CDD:238712"
     misc_feature    order(35550..35552,35568..35570,35628..35630,35634..35639,
                     35685..35687,35751..35759)
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /note="IMP binding site; other site"
                     /db_xref="CDD:238712"
     misc_feature    order(35631..35633,35643..35645,35667..35669,35673..35678,
                     35682..35684,35718..35720)
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238712"
     misc_feature    order(35826..35828,35841..35843,35853..35855)
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /note="interdomain contacts; other site"
                     /db_xref="CDD:238712"
     misc_feature    35826..35834
                     /gene="carB"
                     /locus_tag="ECOK1_0031"
                     /note="partial ornithine binding site; other site"
                     /db_xref="CDD:238712"
     gene            36154..36612
                     /locus_tag="ECOK1_0032"
                     /db_xref="GeneID:12688600"
     CDS             36154..36612
                     /locus_tag="ECOK1_0032"
                     /note="identified by match to protein family HMM PF01797"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200, transposase"
                     /protein_id="YP_006099289.1"
                     /db_xref="GI:386597783"
                     /db_xref="GeneID:12688600"
                     /translation="MGNEKSLAHTRWNCKYHIVFAPKYRRQVFYREKRRAIGCILRKL
                     CEWKSVRILEAECCADHIHMLVEIPPKMSVSGFMGYLKGKSSLMPYEQFGDLKFKYRN
                     REFWCRGYYVDTVGKNTAKIQDYIKHQLEEDKMGEQLSIPYPGSPFTGRK"
     misc_feature    36187..36540
                     /locus_tag="ECOK1_0032"
                     /note="Transposase IS200 like; Region: Y1_Tnp; pfam01797"
                     /db_xref="CDD:250874"
     gene            36902..37297
                     /gene="caiF"
                     /locus_tag="ECOK1_0033"
                     /db_xref="GeneID:12688601"
     CDS             36902..37297
                     /gene="caiF"
                     /locus_tag="ECOK1_0033"
                     /note="identified by similarity to SP:P0AE58"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activatory protein CaiF"
                     /protein_id="YP_006099290.1"
                     /db_xref="GI:386597784"
                     /db_xref="GeneID:12688601"
                     /translation="MCEGCVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNT
                     LTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSRDKLVGVR
                     KTPRIPAVPLTELNREQKWQMMLSKSMRR"
     misc_feature    36956..37294
                     /gene="caiF"
                     /locus_tag="ECOK1_0033"
                     /note="DNA-binding transcriptional activator CaiF;
                     Provisional; Region: PRK11476"
                     /db_xref="CDD:183154"
     gene            complement(37416..38006)
                     /gene="paaY"
                     /locus_tag="ECOK1_0034"
                     /db_xref="GeneID:12688602"
     CDS             complement(37416..38006)
                     /gene="paaY"
                     /locus_tag="ECOK1_0034"
                     /note="identified by similarity to SP:P77181; match to
                     protein family HMM PF00132"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaY"
                     /protein_id="YP_006099291.1"
                     /db_xref="GI:386597785"
                     /db_xref="GeneID:12688602"
                     /translation="MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFVKAGFRGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
                     DLVGRCHAALHETQPLRQMEENRPRLQGTTDVTPKR"
     misc_feature    complement(37419..38006)
                     /gene="paaY"
                     /locus_tag="ECOK1_0034"
                     /note="carnitine operon protein CaiE; Provisional; Region:
                     PRK13627"
                     /db_xref="CDD:184189"
     misc_feature    complement(37512..37976)
                     /gene="paaY"
                     /locus_tag="ECOK1_0034"
                     /note="paaY-like: This group is composed by
                     uncharacterized proteins with similarity to the protein
                     product of the E. coli paaY gene, which is part of the paa
                     gene cluster responsible for phenylacetic acid
                     degradation. Proteins in this group are expected to...;
                     Region: LbH_paaY_like; cd04745"
                     /db_xref="CDD:100058"
     misc_feature    complement(order(37710..37712,37746..37748,37752..37763,
                     37812..37814,37824..37829,37869..37871,37875..37877,
                     37881..37886,37893..37895,37929..37931,37938..37943,
                     37947..37949,37953..37955))
                     /gene="paaY"
                     /locus_tag="ECOK1_0034"
                     /note="putative trimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:100058"
     misc_feature    complement(order(37746..37748,37761..37763,37812..37814))
                     /gene="paaY"
                     /locus_tag="ECOK1_0034"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:100058"
     gene            complement(38012..38905)
                     /gene="caiD"
                     /locus_tag="ECOK1_0035"
                     /db_xref="GeneID:12688603"
     CDS             complement(38012..38905)
                     /gene="caiD"
                     /locus_tag="ECOK1_0035"
                     /EC_number="4.2.1.-"
                     /note="identified by similarity to SP:P31551; match to
                     protein family HMM PF00378"
                     /codon_start=1
                     /transl_table=11
                     /product="carnitinyl-CoA dehydratase"
                     /protein_id="YP_006099292.1"
                     /db_xref="GI:386597786"
                     /db_xref="GeneID:12688603"
                     /translation="MKRQGTTLSANNHALKQYAFFAGMLSSLKKQKWRKGMSESLHLT
                     RNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDDPQLRVAIITGAGEKFFSAGWDL
                     KAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADN
                     ASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMTGRRMGAEEALRWGVVNRVVSQ
                     AELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMPVEEAYRYIRSGVLKHYPSVLHS
                     EDAIEGPLAFAEKRDPVWKGR"
     misc_feature    complement(38015..38797)
                     /gene="caiD"
                     /locus_tag="ECOK1_0035"
                     /note="carnitinyl-CoA dehydratase; Provisional; Region:
                     PRK03580"
                     /db_xref="CDD:179599"
     misc_feature    complement(38210..38785)
                     /gene="caiD"
                     /locus_tag="ECOK1_0035"
                     /note="Crotonase/Enoyl-Coenzyme A (CoA) hydratase
                     superfamily. This superfamily contains a diverse set of
                     enzymes including enoyl-CoA hydratase, napthoate synthase,
                     methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA
                     dehydratase, and dienoyl-CoA isomerase; Region:
                     crotonase-like; cd06558"
                     /db_xref="CDD:119339"
     misc_feature    complement(order(38396..38398,38405..38410,38474..38482,
                     38486..38488,38600..38614,38624..38626,38723..38725,
                     38729..38731))
                     /gene="caiD"
                     /locus_tag="ECOK1_0035"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:119339"
     misc_feature    complement(order(38474..38476,38606..38608))
                     /gene="caiD"
                     /locus_tag="ECOK1_0035"
                     /note="oxyanion hole (OAH) forming residues; other site"
                     /db_xref="CDD:119339"
     misc_feature    complement(order(38210..38215,38222..38224,38267..38269,
                     38276..38278,38309..38311,38318..38323,38327..38332,
                     38336..38341,38354..38359,38363..38371,38375..38377,
                     38393..38404,38438..38449,38510..38512,38534..38536))
                     /gene="caiD"
                     /locus_tag="ECOK1_0035"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119339"
     gene            complement(38906..40474)
                     /locus_tag="ECOK1_0036"
                     /db_xref="GeneID:12688604"
     CDS             complement(38906..40474)
                     /locus_tag="ECOK1_0036"
                     /note="identified by similarity to SP:P31552; match to
                     protein family HMM PF00501"
                     /codon_start=1
                     /transl_table=11
                     /product="putative crotonobetaine/carnitine-CoA ligase"
                     /protein_id="YP_006099293.1"
                     /db_xref="GI:386597787"
                     /db_xref="GeneID:12688604"
                     /translation="MDRGAMDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYS
                     YLELNQEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLL
                     REESTWILQNSQACLLVTSAQFYPMYQQIQQEDASQLRHICLIDMALPADDGVSSFTQ
                     LKNQQPATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRD
                     DDVYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPM
                     MIRTLMVQPPSANDRQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGII
                     GDRPGDKRRWPSIGRAGFCYEAEIRDDHNRPLPAGELGEICIKGVPGKTIFKEYFLNP
                     KATAKVLEADGWLHTGDTGYRDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPK
                     IQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFCFCEQNMAKFKVPSYLEIRKDL
                     PRNCSGKIIRKNLK"
     misc_feature    complement(38909..40459)
                     /locus_tag="ECOK1_0036"
                     /note="putative crotonobetaine/carnitine-CoA ligase;
                     Validated; Region: caiC; PRK08008"
                     /db_xref="CDD:181195"
     misc_feature    complement(38909..40354)
                     /locus_tag="ECOK1_0036"
                     /note="Uncharacterized subfamily of fatty acid CoA ligase
                     (FACL); Region: FACL_DitJ_like; cd05934"
                     /db_xref="CDD:213300"
     misc_feature    complement(order(39893..39898,39902..39919,39926..39928))
                     /locus_tag="ECOK1_0036"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213300"
     misc_feature    complement(order(38930..38932,39170..39172,39203..39205,
                     39212..39214,39248..39250,39494..39511,39569..39574,
                     39917..39919))
                     /locus_tag="ECOK1_0036"
                     /note="putative AMP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213300"
     misc_feature    complement(order(38987..38989,39170..39181,39203..39205,
                     39212..39214,39248..39250,39494..39511,39569..39574,
                     39629..39631,39638..39643,39647..39649,39794..39799,
                     39917..39919))
                     /locus_tag="ECOK1_0036"
                     /note="putative active site [active]"
                     /db_xref="CDD:213300"
     misc_feature    complement(order(38987..38989,39005..39007,39173..39181,
                     39572..39574,39629..39631,39638..39643,39797..39799))
                     /locus_tag="ECOK1_0036"
                     /note="putative CoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213300"
     gene            complement(40532..41749)
                     /gene="caiB"
                     /locus_tag="ECOK1_0037"
                     /db_xref="GeneID:12688605"
     CDS             complement(40532..41749)
                     /gene="caiB"
                     /locus_tag="ECOK1_0037"
                     /EC_number="2.8.3.-"
                     /note="identified by similarity to SP:P31572; match to
                     protein family HMM PF02515"
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA:carnitine CoA-transferase"
                     /protein_id="YP_006099294.1"
                     /db_xref="GI:386597788"
                     /db_xref="GeneID:12688605"
                     /translation="MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEMCPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQIAECFKDIGLAHLLGTPEIPE
                     GTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDI
                     QELVSKGLAKVED"
     misc_feature    complement(40535..41749)
                     /gene="caiB"
                     /locus_tag="ECOK1_0037"
                     /note="crotonobetainyl-CoA:carnitine CoA-transferase;
                     Provisional; Region: PRK03525"
                     /db_xref="CDD:179589"
     gene            complement(41877..43019)
                     /gene="caiA"
                     /locus_tag="ECOK1_0038"
                     /db_xref="GeneID:12688606"
     CDS             complement(41877..43019)
                     /gene="caiA"
                     /locus_tag="ECOK1_0038"
                     /EC_number="1.3.99.-"
                     /note="identified by similarity to SP:P60587; match to
                     protein family HMM PF00441; match to protein family HMM
                     PF02770; match to protein family HMM PF02771; match to
                     protein family HMM PF08028"
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA dehydrogenase"
                     /protein_id="YP_006099295.1"
                     /db_xref="GI:386597789"
                     /db_xref="GeneID:12688606"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQ
                     VLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     misc_feature    complement(41880..43019)
                     /gene="caiA"
                     /locus_tag="ECOK1_0038"
                     /note="crotonobetainyl-CoA dehydrogenase; Validated;
                     Region: PRK03354"
                     /db_xref="CDD:179566"
     misc_feature    complement(41901..43001)
                     /gene="caiA"
                     /locus_tag="ECOK1_0038"
                     /note="Acyl-CoA dehydrogenase; Region: ACAD; cd00567"
                     /db_xref="CDD:173838"
     misc_feature    complement(order(41925..41927,41931..41933,41937..41945,
                     42549..42551,42555..42557,42648..42650,42654..42656,
                     42870..42872))
                     /gene="caiA"
                     /locus_tag="ECOK1_0038"
                     /note="active site"
                     /db_xref="CDD:173838"
     gene            complement(43050..44564)
                     /gene="caiT"
                     /locus_tag="ECOK1_0039"
                     /db_xref="GeneID:12688607"
     CDS             complement(43050..44564)
                     /gene="caiT"
                     /locus_tag="ECOK1_0039"
                     /note="identified by similarity to SP:P31553; match to
                     protein family HMM PF02028; match to protein family HMM
                     TIGR00842"
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine/gamma-butyrobetaine antiporter"
                     /protein_id="YP_006099296.1"
                     /db_xref="GI:386597790"
                     /db_xref="GeneID:12688607"
                     /translation="MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYF
                     FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD"
     misc_feature    complement(43053..44564)
                     /gene="caiT"
                     /locus_tag="ECOK1_0039"
                     /note="L-carnitine/gamma-butyrobetaine antiporter;
                     Provisional; Region: PRK03356"
                     /db_xref="CDD:179568"
     gene            45037..45807
                     /gene="fixA"
                     /locus_tag="ECOK1_0040"
                     /db_xref="GeneID:12688608"
     CDS             45037..45807
                     /gene="fixA"
                     /locus_tag="ECOK1_0040"
                     /note="identified by similarity to SP:P60566; match to
                     protein family HMM PF01012"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta"
                     /protein_id="YP_006099297.1"
                     /db_xref="GI:386597791"
                     /db_xref="GeneID:12688608"
                     /translation="MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEA
                     ACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTAS
                     VLAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVE
                     RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAA
                     WSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI"
     misc_feature    45040..45657
                     /gene="fixA"
                     /locus_tag="ECOK1_0040"
                     /note="The electron transfer flavoprotein (ETF) serves as
                     a specific electron acceptor for various mitochondrial
                     dehydrogenases. ETF transfers electrons to the main
                     respiratory chain via ETF-ubiquinone oxidoreductase. ETF
                     is an heterodimer that consists of an...; Region:
                     ETF_beta; cd01714"
                     /db_xref="CDD:238847"
     misc_feature    order(45052..45057,45139..45141,45148..45150,45220..45222,
                     45388..45393,45397..45402,45415..45426)
                     /gene="fixA"
                     /locus_tag="ECOK1_0040"
                     /note="Ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:238847"
     gene            45822..46763
                     /gene="fixB"
                     /locus_tag="ECOK1_0041"
                     /db_xref="GeneID:12688609"
     CDS             45822..46763
                     /gene="fixB"
                     /locus_tag="ECOK1_0041"
                     /note="identified by similarity to SP:P31574; match to
                     protein family HMM PF00766; match to protein family HMM
                     PF01012"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit alpha"
                     /protein_id="YP_006099298.1"
                     /db_xref="GI:386597792"
                     /db_xref="GeneID:12688609"
                     /translation="MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGTQA
                     IQLGANHVWKLSGKPDERMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYR
                     LNAAVSNDASAVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
                     RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLC
                     KAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQT
                     IFAINKDKNAPIFQYADYGIVGDAVKILPALTVALAR"
     misc_feature    45822..46760
                     /gene="fixB"
                     /locus_tag="ECOK1_0041"
                     /note="putative electron transfer flavoprotein FixB;
                     Provisional; Region: fixB; PRK03363"
                     /db_xref="CDD:235120"
     misc_feature    45876..46283
                     /gene="fixB"
                     /locus_tag="ECOK1_0041"
                     /note="Electron transfer flavoprotein domain; Region: ETF;
                     pfam01012"
                     /db_xref="CDD:250293"
     misc_feature    46386..46646
                     /gene="fixB"
                     /locus_tag="ECOK1_0041"
                     /note="Electron transfer flavoprotein FAD-binding domain;
                     Region: ETF_alpha; pfam00766"
                     /db_xref="CDD:189709"
     gene            46814..48100
                     /gene="fixC"
                     /locus_tag="ECOK1_0042"
                     /db_xref="GeneID:12688610"
     CDS             46814..48100
                     /gene="fixC"
                     /locus_tag="ECOK1_0042"
                     /note="identified by similarity to SP:P68644; match to
                     protein family HMM PF01134; match to protein family HMM
                     PF01266; match to protein family HMM PF01494; match to
                     protein family HMM PF03486"
                     /codon_start=1
                     /transl_table=11
                     /product="protein FixC"
                     /protein_id="YP_006099299.1"
                     /db_xref="GI:386597793"
                     /db_xref="GeneID:12688610"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
                     GVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTD
                     GLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     SAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSA
                     MKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFT
                     IDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL"
     misc_feature    46814..48097
                     /gene="fixC"
                     /locus_tag="ECOK1_0042"
                     /note="putative oxidoreductase FixC; Provisional; Region:
                     PRK10157"
                     /db_xref="CDD:182273"
     misc_feature    46814..48097
                     /gene="fixC"
                     /locus_tag="ECOK1_0042"
                     /note="Short-chain dehydrogenases/reductases (SDR);
                     Region: SDR; cl21454"
                     /db_xref="CDD:271874"
     gene            48097..48384
                     /gene="fixX"
                     /locus_tag="ECOK1_0043"
                     /db_xref="GeneID:12688611"
     CDS             48097..48384
                     /gene="fixX"
                     /locus_tag="ECOK1_0043"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein FixX"
                     /protein_id="YP_006099300.1"
                     /db_xref="GI:386597794"
                     /db_xref="GeneID:12688611"
                     /translation="MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACP
                     AGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG"
     misc_feature    48097..48381
                     /gene="fixX"
                     /locus_tag="ECOK1_0043"
                     /note="ferredoxin-like protein FixX; Provisional; Region:
                     PRK15449"
                     /db_xref="CDD:185346"
     gene            48443..49774
                     /locus_tag="ECOK1_0044"
                     /db_xref="GeneID:12688612"
     CDS             48443..49774
                     /locus_tag="ECOK1_0044"
                     /note="identified by match to protein family HMM PF00083;
                     match to protein family HMM PF07690"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator family transporter"
                     /protein_id="YP_006099301.1"
                     /db_xref="GI:386597795"
                     /db_xref="GeneID:12688612"
                     /translation="MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQL
                     TPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMF
                     VSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
                     VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFG
                     EPVAFEEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLG
                     VGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGI
                     WLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPI
                     FINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG"
     misc_feature    48500..49705
                     /locus_tag="ECOK1_0044"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    48518..49747
                     /locus_tag="ECOK1_0044"
                     /note="Sugar (and other) transporter; Region: Sugar_tr;
                     pfam00083"
                     /db_xref="CDD:249572"
     misc_feature    order(48542..48544,48551..48559,48563..48568,48617..48619,
                     48626..48631,48638..48640,48650..48655,48659..48664,
                     48800..48805,48812..48817,48824..48829,48836..48838,
                     48872..48877,48884..48889,48905..48907,49208..49210,
                     49217..49222,49229..49234,49241..49243,49283..49285,
                     49295..49297,49307..49309,49316..49318,49328..49330,
                     49475..49477,49484..49489,49496..49498,49508..49513,
                     49520..49522,49553..49558,49565..49570,49577..49582,
                     49589..49591)
                     /locus_tag="ECOK1_0044"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            49882..50412
                     /gene="kefF"
                     /locus_tag="ECOK1_0045"
                     /db_xref="GeneID:12688613"
     CDS             49882..50412
                     /gene="kefF"
                     /locus_tag="ECOK1_0045"
                     /note="identified by similarity to SP:P0A754; match to
                     protein family HMM PF02525"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     ancillary protein kefF"
                     /protein_id="YP_006099302.1"
                     /db_xref="GI:386597796"
                     /db_xref="GeneID:12688613"
                     /translation="MILIIYAHPYPHYSHANKRMLEQARTLEGVEIRSLYQLYPDFNI
                     DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLW
                     AVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
                     RHYKQRLLEWQEAHHG"
     misc_feature    49882..50409
                     /gene="kefF"
                     /locus_tag="ECOK1_0045"
                     /note="glutathione-regulated potassium-efflux system
                     ancillary protein KefF; Provisional; Region: PRK00871"
                     /db_xref="CDD:234852"
     gene            50405..52267
                     /gene="kefC"
                     /locus_tag="ECOK1_0046"
                     /db_xref="GeneID:12688614"
     CDS             50405..52267
                     /gene="kefC"
                     /locus_tag="ECOK1_0046"
                     /note="identified by similarity to SP:P03819; match to
                     protein family HMM PF00999; match to protein family HMM
                     PF02254; match to protein family HMM TIGR00932"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefC"
                     /protein_id="YP_006099303.1"
                     /db_xref="GI:386597797"
                     /db_xref="GeneID:12688614"
                     /translation="MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLG
                     LFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAI
                     PLVAMIPLLAASSASTTMGAFVLSALKVAGALALVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLIENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREA
                     DEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQ
                     AGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTK
                     ARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS"
     misc_feature    50405..52264
                     /gene="kefC"
                     /locus_tag="ECOK1_0046"
                     /note="glutathione-regulated potassium-efflux system
                     protein KefC; Provisional; Region: PRK03562"
                     /db_xref="CDD:235131"
     misc_feature    50441..51259
                     /gene="kefC"
                     /locus_tag="ECOK1_0046"
                     /note="transporter, monovalent cation:proton antiporter-2
                     (CPA2) family; Region: 2a37; TIGR00932"
                     /db_xref="CDD:233195"
     misc_feature    51608..51937
                     /gene="kefC"
                     /locus_tag="ECOK1_0046"
                     /note="TrkA-N domain; Region: TrkA_N; pfam02254"
                     /db_xref="CDD:251184"
     gene            52459..52938
                     /gene="folA"
                     /locus_tag="ECOK1_0047"
                     /db_xref="GeneID:12688615"
     CDS             52459..52938
                     /gene="folA"
                     /locus_tag="ECOK1_0047"
                     /EC_number="1.5.1.3"
                     /note="identified by similarity to SP:P0ABQ4; match to
                     protein family HMM PF00186"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="YP_006099304.1"
                     /db_xref="GI:386597798"
                     /db_xref="GeneID:12688615"
                     /translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGR
                     HTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQ
                     FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     misc_feature    52462..52929
                     /gene="folA"
                     /locus_tag="ECOK1_0047"
                     /note="Dihydrofolate reductase (DHFR). Reduces
                     7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH
                     as a cofactor. This is an essential step in the
                     biosynthesis of deoxythymidine phosphate since
                     5,6,7,8-tetrahydrofolate is required to regenerate 5;
                     Region: DHFR; cd00209"
                     /db_xref="CDD:238127"
     misc_feature    order(52471..52473,52522..52524,52537..52539,52627..52629,
                     52738..52740,52756..52758,52795..52797)
                     /gene="folA"
                     /locus_tag="ECOK1_0047"
                     /note="folate binding site [chemical binding]; other site"
                     /db_xref="CDD:238127"
     misc_feature    order(52477..52479,52498..52500,52588..52596,52648..52650,
                     52741..52752)
                     /gene="folA"
                     /locus_tag="ECOK1_0047"
                     /note="NADP+ binding site [chemical binding]; other site"
                     /db_xref="CDD:238127"
     gene            53024..53257
                     /gene="ccdA"
                     /locus_tag="ECOK1_0048"
                     /db_xref="GeneID:12688616"
     CDS             53024..53257
                     /gene="ccdA"
                     /locus_tag="ECOK1_0048"
                     /note="identified by similarity to SP:P62552; match to
                     protein family HMM PF07362"
                     /codon_start=1
                     /transl_table=11
                     /product="post-segregation antitoxin CcdA"
                     /protein_id="YP_006099305.1"
                     /db_xref="GI:386597799"
                     /db_xref="GeneID:12688616"
                     /translation="MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKH
                     AATRWREENAEAIAALNQLADETGCFSDEYRSF"
     misc_feature    53039..53254
                     /gene="ccdA"
                     /locus_tag="ECOK1_0048"
                     /note="Post-segregation antitoxin CcdA; Region: CcdA;
                     pfam07362"
                     /db_xref="CDD:148779"
     gene            53260..53575
                     /locus_tag="ECOK1_0050"
                     /note="cytotoxic protein CcdB homolog, authentic
                     frameshift; this gene contains a frame shift which is not
                     the result of sequencing error; identified by similarity
                     to SP:Q52043"
                     /pseudo
                     /db_xref="GeneID:12688617"
     gene            complement(53572..54420)
                     /gene="apaH"
                     /locus_tag="ECOK1_0049"
                     /db_xref="GeneID:12688618"
     CDS             complement(53572..54420)
                     /gene="apaH"
                     /locus_tag="ECOK1_0049"
                     /EC_number="3.6.1.41"
                     /note="identified by similarity to SP:P05637; match to
                     protein family HMM PF00149; match to protein family HMM
                     TIGR00668"
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase
                     (symmetrical)"
                     /protein_id="YP_006099306.1"
                     /db_xref="GI:386597800"
                     /db_xref="GeneID:12688618"
                     /translation="MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPG
                     SLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQIDKEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVA
                     EEYNIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLSE
                     GEAVAS"
     misc_feature    complement(53584..54420)
                     /gene="apaH"
                     /locus_tag="ECOK1_0049"
                     /note="bis(5'-nucleosyl)-tetraphosphatase (symmetrical);
                     Region: apaH; TIGR00668"
                     /db_xref="CDD:233082"
     misc_feature    complement(53644..54414)
                     /gene="apaH"
                     /locus_tag="ECOK1_0049"
                     /note="Escherichia coli ApaH and related proteins,
                     metallophosphatase domain; Region: MPP_ApaH; cd07422"
                     /db_xref="CDD:163665"
     misc_feature    complement(order(53674..53676,53689..53691,53740..53742,
                     54061..54063,54223..54228,54298..54303,54310..54312,
                     54391..54393,54397..54399))
                     /gene="apaH"
                     /locus_tag="ECOK1_0049"
                     /note="active site"
                     /db_xref="CDD:163665"
     misc_feature    complement(order(53740..53742,54061..54063,54226..54228,
                     54310..54312,54391..54393,54397..54399))
                     /gene="apaH"
                     /locus_tag="ECOK1_0049"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163665"
     gene            complement(54427..54804)
                     /gene="apaG"
                     /locus_tag="ECOK1_0051"
                     /db_xref="GeneID:12688619"
     CDS             complement(54427..54804)
                     /gene="apaG"
                     /locus_tag="ECOK1_0051"
                     /note="identified by similarity to SP:P62675; match to
                     protein family HMM PF04379"
                     /codon_start=1
                     /transl_table=11
                     /product="protein ApaG"
                     /protein_id="YP_006099307.1"
                     /db_xref="GI:386597801"
                     /db_xref="GeneID:12688619"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMI
                     DENGVPFSIDIPVFRLAVPTLIH"
     misc_feature    complement(54430..54804)
                     /gene="apaG"
                     /locus_tag="ECOK1_0051"
                     /note="CO2+/MG2+ efflux protein ApaG; Reviewed; Region:
                     apaG; PRK05461"
                     /db_xref="CDD:180098"
     gene            complement(54807..55628)
                     /gene="ksgA"
                     /locus_tag="ECOK1_0052"
                     /db_xref="GeneID:12688620"
     CDS             complement(54807..55628)
                     /gene="ksgA"
                     /locus_tag="ECOK1_0052"
                     /EC_number="2.1.1.-"
                     /note="identified by match to protein family HMM PF00398;
                     match to protein family HMM TIGR00755"
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyladenosine transferase"
                     /protein_id="YP_006099308.1"
                     /db_xref="GI:386597802"
                     /db_xref="GeneID:12688620"
                     /translation="MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAA
                     KMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES"
     misc_feature    complement(54828..55628)
                     /gene="ksgA"
                     /locus_tag="ECOK1_0052"
                     /note="16S ribosomal RNA methyltransferase KsgA/Dim1
                     family protein; Reviewed; Region: ksgA; PRK00274"
                     /db_xref="CDD:234708"
     gene            complement(55625..56614)
                     /gene="pdxA"
                     /locus_tag="ECOK1_0053"
                     /db_xref="GeneID:12688621"
     CDS             complement(55625..56614)
                     /gene="pdxA"
                     /locus_tag="ECOK1_0053"
                     /EC_number="1.1.1.262"
                     /note="identified by similarity to SP:P19624; match to
                     protein family HMM PF04166; match to protein family HMM
                     TIGR00557"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase"
                     /protein_id="YP_006099309.1"
                     /db_xref="GI:386597803"
                     /db_xref="GeneID:12688621"
                     /translation="MVKTQRVVITPGEPAGIGPDLIVQLAQREWPVELVVCADATLLT
                     DRAAMLGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRESVTVGQLAVENGHYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPVLNELREQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ"
     misc_feature    complement(55628..56614)
                     /gene="pdxA"
                     /locus_tag="ECOK1_0053"
                     /note="4-hydroxythreonine-4-phosphate dehydrogenase;
                     Reviewed; Region: pdxA; PRK00232"
                     /db_xref="CDD:234696"
     gene            complement(56614..57900)
                     /gene="surA"
                     /locus_tag="ECOK1_0054"
                     /db_xref="GeneID:12688622"
     CDS             complement(56614..57900)
                     /gene="surA"
                     /locus_tag="ECOK1_0054"
                     /EC_number="5.2.1.8"
                     /note="identified by similarity to SP:Q3Z5V6; match to
                     protein family HMM PF00639; match to protein family HMM
                     PF09312"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone/peptidyl-prolyl cis-trans isomerase
                     SurA"
                     /protein_id="YP_006099310.1"
                     /db_xref="GI:386597804"
                     /db_xref="GeneID:12688622"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIAN
                     IAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
                     AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIA
                     HSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGE
                     SKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGS
                     ANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAA
                     QKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN"
     misc_feature    complement(56617..57846)
                     /gene="surA"
                     /locus_tag="ECOK1_0054"
                     /note="peptidyl-prolyl cis-trans isomerase SurA;
                     Provisional; Region: PRK10770"
                     /db_xref="CDD:236758"
     misc_feature    complement(57475..57789)
                     /gene="surA"
                     /locus_tag="ECOK1_0054"
                     /note="SurA N-terminal domain; Region: SurA_N; pfam09312"
                     /db_xref="CDD:150092"
     misc_feature    complement(57085..57369)
                     /gene="surA"
                     /locus_tag="ECOK1_0054"
                     /note="PPIC-type PPIASE domain; Region: Rotamase;
                     pfam00639"
                     /db_xref="CDD:250020"
     misc_feature    complement(56755..57036)
                     /gene="surA"
                     /locus_tag="ECOK1_0054"
                     /note="PPIC-type PPIASE domain; Region: Rotamase;
                     pfam00639"
                     /db_xref="CDD:250020"
     gene            complement(57953..60307)
                     /gene="imp"
                     /locus_tag="ECOK1_0055"
                     /db_xref="GeneID:12688623"
     CDS             complement(57953..60307)
                     /gene="imp"
                     /locus_tag="ECOK1_0055"
                     /note="identified by similarity to SP:P31554; match to
                     protein family HMM PF03968; match to protein family HMM
                     PF04453"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS-assembly protein"
                     /protein_id="YP_006099311.1"
                     /db_xref="GI:386597805"
                     /db_xref="GeneID:12688623"
                     /translation="MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQ
                     GDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLSQAGAGLMELDYLPSDKVYKDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKV
                     SDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEP
                     QLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTE
                     AKLLATHYQQTNLDWYNSRNTTKLAESANRVMPQFKVDGRMVFERDMEMLAPGYTQTL
                     EPRAQYLYVPYRDQSKIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRI
                     YDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISDRWGLRG
                     GIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGI
                     SQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWD
                     NDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL"
     misc_feature    complement(57962..60307)
                     /gene="imp"
                     /locus_tag="ECOK1_0055"
                     /note="LPS assembly outer membrane complex protein LptD;
                     Provisional; Region: PRK03761"
                     /db_xref="CDD:235158"
     misc_feature    complement(59723..60151)
                     /gene="imp"
                     /locus_tag="ECOK1_0055"
                     /note="OstA-like protein; Region: OstA; pfam03968"
                     /db_xref="CDD:252284"
     misc_feature    complement(58217..59380)
                     /gene="imp"
                     /locus_tag="ECOK1_0055"
                     /note="Organic solvent tolerance protein; Region: OstA_C;
                     pfam04453"
                     /db_xref="CDD:252606"
     gene            60562..61377
                     /gene="djlA"
                     /locus_tag="ECOK1_0056"
                     /db_xref="GeneID:12688624"
     CDS             60562..61377
                     /gene="djlA"
                     /locus_tag="ECOK1_0056"
                     /note="identified by similarity to SP:P31680; match to
                     protein family HMM PF00226"
                     /codon_start=1
                     /transl_table=11
                     /product="protein DjlA, DnaJ family"
                     /protein_id="YP_006099312.1"
                     /db_xref="GI:386597806"
                     /db_xref="GeneID:12688624"
                     /translation="MQYWGKIIGVAVALIMGGGFWGVVLGLLIGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFR
                     VGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEE
                     LGISRAQFDQFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDA
                     TTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK"
     misc_feature    60562..61374
                     /gene="djlA"
                     /locus_tag="ECOK1_0056"
                     /note="Dna-J like membrane chaperone protein; Provisional;
                     Region: djlA; PRK09430"
                     /db_xref="CDD:236512"
     misc_feature    <60568..60663
                     /gene="djlA"
                     /locus_tag="ECOK1_0056"
                     /note="Domain of unknown function (DUF4311); Region:
                     DUF4311; cl11919"
                     /db_xref="CDD:264486"
     misc_feature    60730..61047
                     /gene="djlA"
                     /locus_tag="ECOK1_0056"
                     /note="N-terminal tellurium resistance protein terB-like
                     domain of heat shock DnaJ-like proteins; Region:
                     terB_like_DjlA; cd07316"
                     /db_xref="CDD:143585"
     misc_feature    order(60766..60768,60787..60789,60988..60990,61009..61011)
                     /gene="djlA"
                     /locus_tag="ECOK1_0056"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:143585"
     misc_feature    61186..61347
                     /gene="djlA"
                     /locus_tag="ECOK1_0056"
                     /note="DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock
                     protein 40) proteins are highly conserved and play crucial
                     roles in protein translation, folding, unfolding,
                     translocation, and degradation. They act primarily by
                     stimulating the ATPase activity of Hsp70s; Region: DnaJ;
                     cd06257"
                     /db_xref="CDD:99751"
     misc_feature    order(61258..61266,61312..61314,61321..61326,61333..61338)
                     /gene="djlA"
                     /locus_tag="ECOK1_0056"
                     /note="HSP70 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99751"
     gene            complement(61527..62186)
                     /locus_tag="ECOK1_0057"
                     /db_xref="GeneID:12688625"
     CDS             complement(61527..62186)
                     /locus_tag="ECOK1_0057"
                     /note="identified by match to protein family HMM PF00849"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="YP_006099313.1"
                     /db_xref="GI:386597807"
                     /db_xref="GeneID:12688625"
                     /translation="MGMENYNPPQDPWLVVLYQDDHIMVVNKPSGLLSVPGRLEEHKD
                     SVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAD
                     F"
     misc_feature    complement(61530..>62162)
                     /locus_tag="ECOK1_0057"
                     /note="Pseudouridylate synthases, 23S RNA-specific
                     [Translation, ribosomal structure and biogenesis]; Region:
                     RluA; COG0564"
                     /db_xref="CDD:223638"
     misc_feature    complement(61581..62120)
                     /locus_tag="ECOK1_0057"
                     /note="Pseudouridine synthase, RsuA/RluD family; Region:
                     PseudoU_synth_RluCD_like; cd02869"
                     /db_xref="CDD:211346"
     misc_feature    complement(order(61692..61694,61995..62006))
                     /locus_tag="ECOK1_0057"
                     /note="active site"
                     /db_xref="CDD:211346"
     gene            complement(62198..65104)
                     /gene="rapA"
                     /locus_tag="ECOK1_0058"
                     /db_xref="GeneID:12688626"
     CDS             complement(62198..65104)
                     /gene="rapA"
                     /locus_tag="ECOK1_0058"
                     /EC_number="3.6.1.-"
                     /note="identified by similarity to SP:P60240; match to
                     protein family HMM PF00176; match to protein family HMM
                     PF00271; match to protein family HMM PF04851"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase associated protein RapA"
                     /protein_id="YP_006099314.1"
                     /db_xref="GI:386597808"
                     /db_xref="GeneID:12688626"
                     /translation="MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDL
                     LVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSD
                     SEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLE
                     QGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVL
                     TPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKL
                     SAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ"
     misc_feature    complement(62207..65101)
                     /gene="rapA"
                     /locus_tag="ECOK1_0058"
                     /note="ATP-dependent helicase HepA; Validated; Region:
                     PRK04914"
                     /db_xref="CDD:235319"
     misc_feature    complement(64157..64588)
                     /gene="rapA"
                     /locus_tag="ECOK1_0058"
                     /note="DEAD-like helicases superfamily. A diverse family
                     of proteins involved in ATP-dependent RNA or DNA
                     unwinding. This domain contains the ATP-binding region;
                     Region: DEXDc; cd00046"
                     /db_xref="CDD:238005"
     misc_feature    complement(64553..64567)
                     /gene="rapA"
                     /locus_tag="ECOK1_0058"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238005"
     misc_feature    complement(64256..64267)
                     /gene="rapA"
                     /locus_tag="ECOK1_0058"
                     /note="putative Mg++ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238005"
     misc_feature    complement(63299..63667)
                     /gene="rapA"
                     /locus_tag="ECOK1_0058"
                     /note="Helicase superfamily c-terminal domain; associated
                     with DEXDc-, DEAD-, and DEAH-box proteins, yeast
                     initiation factor 4A, Ski2p, and Hepatitis C virus NS3
                     helicases; this domain is found in a wide variety of
                     helicases and helicase related proteins; may...; Region:
                     HELICc; cd00079"
                     /db_xref="CDD:238034"
     misc_feature    complement(order(63410..63418,63497..63502,63563..63574))
                     /gene="rapA"
                     /locus_tag="ECOK1_0058"
                     /note="nucleotide binding region [chemical binding]; other
                     site"
                     /db_xref="CDD:238034"
     misc_feature    complement(order(63308..63310,63317..63319,63329..63331,
                     63392..63394))
                     /gene="rapA"
                     /locus_tag="ECOK1_0058"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238034"
     misc_feature    complement(62207..63295)
                     /gene="rapA"
                     /locus_tag="ECOK1_0058"
                     /note="RNA polymerase recycling family C-terminal; Region:
                     RapA_C; pfam12137"
                     /db_xref="CDD:256866"
     gene            complement(65268..67619)
                     /gene="polB"
                     /locus_tag="ECOK1_0059"
                     /db_xref="GeneID:12688627"
     CDS             complement(65268..67619)
                     /gene="polB"
                     /locus_tag="ECOK1_0059"
                     /EC_number="2.7.7.7"
                     /note="identified by similarity to SP:P21189; match to
                     protein family HMM PF00136; match to protein family HMM
                     PF03104"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="YP_006099315.1"
                     /db_xref="GI:386597809"
                     /db_xref="GeneID:12688627"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFLLATDNGPLQVTLAPQESVAF
                     IPADHVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVT
                     VYEADVRPPERYLMERFITSPVWVEGDMRNGAIVNARLKPHPDYRPPLKWVSIDIETT
                     RHGELYCIGLEGCGQRIVYMLGPENGDASALDFELEYVASRPLLLEKLNAWFATHDPD
                     VIIGWNVVQFDLRMLQKHAERYRIPLRLGRDNSELEWREHGFKNDVFFAQAKGRLIID
                     GIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLK
                     DCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLG
                     EVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLASSITMRGHQIMRQTKTLIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIG
                     RALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDTRL
                     VYRKRLRRPLSEYQRNVPPHVRAARLADEENHKRGRPLQYQNRGTIKYVWTTNGPEPL
                     DYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF"
     misc_feature    complement(65271..67619)
                     /gene="polB"
                     /locus_tag="ECOK1_0059"
                     /note="DNA polymerase II; Reviewed; Region: PRK05762"
                     /db_xref="CDD:235595"
     misc_feature    complement(66588..67178)
                     /gene="polB"
                     /locus_tag="ECOK1_0059"
                     /note="DEDDy 3'-5' exonuclease domain of Escherichia coli
                     DNA polymerase II and similar bacterial family-B DNA
                     polymerases; Region: DNA_polB_II_exo; cd05784"
                     /db_xref="CDD:99827"
     misc_feature    complement(order(66615..66617,66627..66629,66741..66746,
                     66933..66941,66948..66953,67143..67154))
                     /gene="polB"
                     /locus_tag="ECOK1_0059"
                     /note="active site"
                     /db_xref="CDD:99827"
     misc_feature    complement(order(66615..66617,66627..66629,66933..66935,
                     67146..67148,67152..67154))
                     /gene="polB"
                     /locus_tag="ECOK1_0059"
                     /note="catalytic site [active]"
                     /db_xref="CDD:99827"
     misc_feature    complement(order(66615..66617,66627..66629,66741..66746,
                     66936..66941,66948..66953,67143..67151))
                     /gene="polB"
                     /locus_tag="ECOK1_0059"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99827"
     misc_feature    complement(65313..66431)
                     /gene="polB"
                     /locus_tag="ECOK1_0059"
                     /note="DNA polymerase type-II subfamily catalytic domain.
                     Bacteria contain five DNA polymerases (I, II, III, IV and
                     V). DNA polymerase II (Pol II) is a prototype for the
                     B-family of polymerases. The role of Pol II in a variety
                     of cellular activities, such as...; Region: POLBc_Pol_II;
                     cd05537"
                     /db_xref="CDD:99920"
     misc_feature    complement(order(65979..65981,66129..66131,66141..66143,
                     66189..66191,66348..66356,66363..66365))
                     /gene="polB"
                     /locus_tag="ECOK1_0059"
                     /note="active site"
                     /db_xref="CDD:99920"
     misc_feature    complement(order(65979..65981,65985..65987))
                     /gene="polB"
                     /locus_tag="ECOK1_0059"
                     /note="metal-binding site"
                     /db_xref="CDD:99920"
     gene            complement(67694..68389)
                     /gene="araD"
                     /locus_tag="ECOK1_0060"
                     /db_xref="GeneID:12688628"
     CDS             complement(67694..68389)
                     /gene="araD"
                     /locus_tag="ECOK1_0060"
                     /EC_number="5.1.3.4"
                     /note="identified by similarity to SP:P08203; match to
                     protein family HMM PF00596; match to protein family HMM
                     TIGR00760"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="YP_006099316.1"
                     /db_xref="GI:386597810"
                     /db_xref="GeneID:12688628"
                     /translation="MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRGRGVLVIKPS
                     GVDYSTMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHAT
                     IWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKH
                     YLRKHGAKAYYGQ"
     misc_feature    complement(67721..68383)
                     /gene="araD"
                     /locus_tag="ECOK1_0060"
                     /note="Class II Aldolase and Adducin head (N-terminal)
                     domain. Aldolases are ubiquitous enzymes catalyzing
                     central steps of carbohydrate metabolism. Based on
                     enzymatic mechanisms, this superfamily has been divided
                     into two distinct classes (Class I and II); Region:
                     Aldolase_II; cd00398"
                     /db_xref="CDD:238232"
     misc_feature    complement(order(67733..67735,67793..67795,67814..67816,
                     67826..67828,67847..67849,67880..67882,67997..67999,
                     68039..68044,68048..68050,68069..68077,68090..68095,
                     68099..68101,68240..68245,68249..68251,68321..68323,
                     68345..68347,68357..68359))
                     /gene="araD"
                     /locus_tag="ECOK1_0060"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238232"
     misc_feature    complement(order(67877..67879,68099..68101,68105..68107,
                     68162..68170,68255..68260,68306..68308))
                     /gene="araD"
                     /locus_tag="ECOK1_0060"
                     /note="active site"
                     /db_xref="CDD:238232"
     misc_feature    complement(order(67877..67879,68099..68101,68105..68107))
                     /gene="araD"
                     /locus_tag="ECOK1_0060"
                     /note="Zn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238232"
     gene            complement(68589..70091)
                     /gene="araA"
                     /locus_tag="ECOK1_0061"
                     /db_xref="GeneID:12688629"
     CDS             complement(68589..70091)
                     /gene="araA"
                     /locus_tag="ECOK1_0061"
                     /EC_number="5.3.1.4"
                     /note="identified by match to protein family HMM PF02610"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="YP_006099317.1"
                     /db_xref="GI:386597811"
                     /db_xref="GeneID:12688629"
                     /translation="MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKL
                     PCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
                     GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR"
     misc_feature    complement(68592..70091)
                     /gene="araA"
                     /locus_tag="ECOK1_0061"
                     /note="L-arabinose isomerase; Provisional; Region:
                     PRK02929"
                     /db_xref="CDD:179503"
     misc_feature    complement(68619..70073)
                     /gene="araA"
                     /locus_tag="ECOK1_0061"
                     /note="L-Arabinose isomerase (AI) catalyzes the
                     isomerization of L-arabinose to L-ribulose, the first
                     reaction in its conversion into D-xylulose-5-phosphate, an
                     intermediate in the pentose phosphate pathway, which
                     allows L-arabinose to be used as a carbon...; Region:
                     L-arabinose_isomerase; cd03557"
                     /db_xref="CDD:239619"
     misc_feature    complement(order(69249..69254,69279..69281,69444..69446,
                     69456..69476,69495..69497,69504..69506,69540..69542,
                     69561..69563,69669..69674,69828..69830,69888..69890,
                     69897..69899,69909..69911))
                     /gene="araA"
                     /locus_tag="ECOK1_0061"
                     /note="putative hexamer (dimer of trimers) interface
                     [polypeptide binding]; other site"
                     /db_xref="CDD:239619"
     misc_feature    complement(order(68619..68624,68691..68693,68745..68747,
                     68754..68756,68763..68765,68772..68777,68820..68822,
                     68826..68831,68835..68837,68892..68900,69075..69092,
                     69522..69533,69615..69617,69648..69650,69654..69656,
                     69669..69671,69675..69680,69687..69689,69696..69701,
                     69708..69713,69729..69731,69738..69746,69753..69755,
                     69759..69761,69765..69767,69774..69776,69780..69782,
                     69828..69839,69843..69845))
                     /gene="araA"
                     /locus_tag="ECOK1_0061"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239619"
     misc_feature    complement(order(68742..68747,69093..69095,69174..69176,
                     69255..69257,69843..69845))
                     /gene="araA"
                     /locus_tag="ECOK1_0061"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:239619"
     misc_feature    complement(order(68742..68744,69093..69095,69174..69176))
                     /gene="araA"
                     /locus_tag="ECOK1_0061"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239619"
     gene            complement(70102..71802)
                     /gene="araB"
                     /locus_tag="ECOK1_0062"
                     /db_xref="GeneID:12688630"
     CDS             complement(70102..71802)
                     /gene="araB"
                     /locus_tag="ECOK1_0062"
                     /EC_number="2.7.1.16"
                     /note="identified by similarity to SP:P08204; match to
                     protein family HMM PF00370; match to protein family HMM
                     PF02782; match to protein family HMM TIGR01234"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulokinase"
                     /protein_id="YP_006099318.1"
                     /db_xref="GI:386597812"
                     /db_xref="GeneID:12688630"
                     /translation="MAIAIGLDFGSDSVRALAVDCATGEEIATSVEWYPRWQKGQFCD
                     APNNQFRHHPRDYIESMEAALKTVLAELSAEQRAAVVGIGVDTTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKI
                     LHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLP
                     PASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAG
                     QSAFGDIYAWFGRVLSWPLEQLAAQHPELKEQINASQKQLLPALTEAWAKNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATTFGARAIMECFTDQGI
                     AVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     SAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYPPTSAPAQAAQAVPTL
                     "
     misc_feature    complement(70144..71802)
                     /gene="araB"
                     /locus_tag="ECOK1_0062"
                     /note="ribulokinase; Provisional; Region: PRK04123"
                     /db_xref="CDD:235221"
     misc_feature    complement(70261..71799)
                     /gene="araB"
                     /locus_tag="ECOK1_0062"
                     /note="Ribulokinases; belongs to the FGGY family of
                     carbohydrate kinases; Region: FGGY_RBK; cd07781"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(70261..70266,70300..70317,70321..70326,
                     70330..70338,70342..70344,70585..70587,70597..70599,
                     70807..70815,70825..70827,70831..70857,70864..70866,
                     70870..70872,70960..70968,70972..70974,70996..70998,
                     71002..71004,71059..71073,71167..71175,71185..71190,
                     71197..71202,71338..71340,71353..71355,71359..71370,
                     71545..71562,71716..71718,71728..71733,71746..71748,
                     71752..71754,71758..71760,71779..71781,71785..71787,
                     71791..71793))
                     /gene="araB"
                     /locus_tag="ECOK1_0062"
                     /note="N- and C-terminal domain interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(70336..70338,70408..70410,70420..70428,
                     70669..70671,70774..70776,70786..70788,70909..70911,
                     70918..70926,70978..70983,71446..71448,71533..71535,
                     71539..71541,71758..71760,71764..71775,71779..71781))
                     /gene="araB"
                     /locus_tag="ECOK1_0062"
                     /note="active site"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(70408..70410,70420..70428,70660..70662,
                     70666..70671,70774..70779,70783..70788,70918..70926,
                     70981..70983,71758..71760,71764..71775,71779..71781))
                     /gene="araB"
                     /locus_tag="ECOK1_0062"
                     /note="MgATP binding site [chemical binding]; other site"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(70981..70983,71770..71772,71779..71781))
                     /gene="araB"
                     /locus_tag="ECOK1_0062"
                     /note="catalytic site [active]"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(70981..70983,71779..71781))
                     /gene="araB"
                     /locus_tag="ECOK1_0062"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(70807..70809,70909..70911,70918..70920,
                     70978..70983,71182..71184,71341..71343,71446..71448,
                     71533..71541,71770..71775))
                     /gene="araB"
                     /locus_tag="ECOK1_0062"
                     /note="carbohydrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:198358"
     misc_feature    complement(order(70534..70542,70546..70572,70606..70611,
                     70624..70626,70630..70632,70747..70764,70771..70773,
                     70783..70785))
                     /gene="araB"
                     /locus_tag="ECOK1_0062"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:198358"
     gene            72141..72986
                     /gene="araC"
                     /locus_tag="ECOK1_0063"
                     /db_xref="GeneID:12688631"
     CDS             72141..72986
                     /gene="araC"
                     /locus_tag="ECOK1_0063"
                     /note="identified by similarity to SP:P11765; match to
                     protein family HMM PF00165; match to protein family HMM
                     PF02311"
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose operon regulatory protein"
                     /protein_id="YP_006099319.1"
                     /db_xref="GI:386597813"
                     /db_xref="GeneID:12688631"
                     /translation="MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAHEWYHQWVYFRPRA
                     YWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLL
                     LRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RAGCE"
     misc_feature    72141..72983
                     /gene="araC"
                     /locus_tag="ECOK1_0063"
                     /note="DNA-binding transcriptional regulator AraC;
                     Provisional; Region: PRK10572"
                     /db_xref="CDD:236717"
     misc_feature    72201..72608
                     /gene="araC"
                     /locus_tag="ECOK1_0063"
                     /note="AraC-like ligand binding domain; Region:
                     AraC_binding; pfam02311"
                     /db_xref="CDD:145456"
     misc_feature    72696..72821
                     /gene="araC"
                     /locus_tag="ECOK1_0063"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:249644"
     misc_feature    72861..72971
                     /gene="araC"
                     /locus_tag="ECOK1_0063"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:249644"
     gene            73251..73373
                     /locus_tag="ECOK1_0064"
                     /note="transposase, degenerate; this region contains one
                     or more premature stops and/or frameshifts"
                     /pseudo
                     /db_xref="GeneID:12688632"
     gene            73501..74349
                     /locus_tag="ECOK1_0065"
                     /db_xref="GeneID:12688633"
     CDS             73501..74349
                     /locus_tag="ECOK1_0065"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099320.1"
                     /db_xref="GI:386597814"
                     /db_xref="GeneID:12688633"
                     /translation="MSKRNDITDGIFATTKKYGLVYTEELGWIDLGHAQGQDARILKR
                     KLEQEHFSTYYDEFHDWYFPVDYHQEMGIRKKILGVDLTFHTGVYTKVMVRSCLSPTL
                     KARVALTLMYGTAKRFEAWQNSFIFNWYTDSGFSAEDLVSDLIGFYRVFGTGPDPLLL
                     AKPLSYTKALQIWDTYGAPGNFKNTEFTPFLFTTHPPFKKNQLIKKKLPEWLNYIKPL
                     DESFSILLYNQYNNRPVTNYYKDKNRINHELYSSLSSSGAIKFSESPFERPLFLFLNP
                     HYPHRS"
     gene            74933..75697
                     /locus_tag="ECOK1_0066"
                     /db_xref="GeneID:12688634"
     CDS             74933..75697
                     /locus_tag="ECOK1_0066"
                     /note="identified by similarity to SP:P30149; match to
                     protein family HMM PF09335"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099321.1"
                     /db_xref="GI:386597815"
                     /db_xref="GeneID:12688634"
                     /translation="MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELSFWYAWLAGIIGCLMGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPQFYFLPGI
                     LAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLL
                     WLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGV"
     misc_feature    74954..75550
                     /locus_tag="ECOK1_0066"
                     /note="Uncharacterized membrane-associated protein
                     [Function unknown]; Region: DedA; COG0586"
                     /db_xref="CDD:223659"
     gene            complement(75811..76509)
                     /gene="thiQ"
                     /locus_tag="ECOK1_0067"
                     /db_xref="GeneID:12688635"
     CDS             complement(75811..76509)
                     /gene="thiQ"
                     /locus_tag="ECOK1_0067"
                     /note="identified by similarity to SP:P31548; match to
                     protein family HMM PF00005; match to protein family HMM
                     TIGR01277"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter ATP-binding protein"
                     /protein_id="YP_006099322.1"
                     /db_xref="GI:386597816"
                     /db_xref="GeneID:12688635"
                     /translation="MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNL
                     IAGFLTPASGLLTIDDVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKL
                     NAAQQKKMHAIAHQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
                     DPALRQEMLTLVSSSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTDELL
                     SGKASASALLGIKG"
     misc_feature    complement(75817..76509)
                     /gene="thiQ"
                     /locus_tag="ECOK1_0067"
                     /note="thiamine transporter ATP-binding subunit;
                     Provisional; Region: thiQ; PRK10771"
                     /db_xref="CDD:182716"
     misc_feature    complement(75874..76506)
                     /gene="thiQ"
                     /locus_tag="ECOK1_0067"
                     /note="ATP-binding cassette domain of the thiamine
                     transport system; Region: ABC_ThiQ_thiamine_transporter;
                     cd03298"
                     /db_xref="CDD:213265"
     misc_feature    complement(76393..76416)
                     /gene="thiQ"
                     /locus_tag="ECOK1_0067"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(order(75946..75948,76045..76050,76276..76278,
                     76390..76398,76402..76407))
                     /gene="thiQ"
                     /locus_tag="ECOK1_0067"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(76276..76287)
                     /gene="thiQ"
                     /locus_tag="ECOK1_0067"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(76093..76122)
                     /gene="thiQ"
                     /locus_tag="ECOK1_0067"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(76045..76062)
                     /gene="thiQ"
                     /locus_tag="ECOK1_0067"
                     /note="Walker B; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(76027..76038)
                     /gene="thiQ"
                     /locus_tag="ECOK1_0067"
                     /note="D-loop; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(75940..75960)
                     /gene="thiQ"
                     /locus_tag="ECOK1_0067"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213265"
     gene            complement(76493..78103)
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /db_xref="GeneID:12688636"
     CDS             complement(76493..78103)
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /note="identified by similarity to SP:P31549; match to
                     protein family HMM PF00528; match to protein family HMM
                     TIGR01253"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter,
                     permease protein"
                     /protein_id="YP_006099323.1"
                     /db_xref="GI:386597817"
                     /db_xref="GeneID:12688636"
                     /translation="MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGDWV
                     AVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRQMLLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLASLWQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     ALENIPGEQRQLAAQLGMHGWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
                     GGPQATTIELAIYQALSYDYDPARAAMLALIQMVCCLGLVLLSQRLSKAIAPGTTLLQ
                     GWRDPDDRLHSRICDTALIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTS
                     LRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFL
                     LLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFLLFTVIEKIPGRNVKTD"
     misc_feature    complement(76499..78073)
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /note="thiamine transporter membrane protein; Reviewed;
                     Region: thiP; PRK09433"
                     /db_xref="CDD:181853"
     misc_feature    complement(77339..77935)
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(77339..77344,77351..77356,77363..77368,
                     77372..77377,77384..77389,77417..77422,77456..77461,
                     77468..77479,77498..77500,77507..77512,77552..77554,
                     77603..77605,77612..77617,77627..77629,77633..77638,
                     77645..77647,77651..77653,77660..77665,77768..77770,
                     77774..77779,77786..77815,77819..77830,77858..77860,
                     77873..77878,77885..77890))
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(77462..77479,77768..77812))
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(77387..77389,77417..77419,77426..77428,
                     77459..77461,77678..77680,77768..77770))
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(77531..77533,77543..77548,77564..77602))
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(76571..77113)
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(76571..76576,76583..76588,76616..76621,
                     76658..76663,76670..76681,76700..76702,76709..76714,
                     76754..76756,76805..76807,76814..76819,76829..76831,
                     76835..76840,76847..76849,76853..76855,76859..76864,
                     76931..76933,76937..76942,76949..76978,76982..76993,
                     77033..77035,77048..77053,77060..77065))
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(76664..76681,76931..76975))
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(76586..76588,76616..76618,76625..76627,
                     76661..76663,76877..76879,76931..76933))
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(76733..76735,76745..76750,76766..76804))
                     /gene="thiP"
                     /locus_tag="ECOK1_0068"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(78079..79062)
                     /gene="thiB"
                     /locus_tag="ECOK1_0069"
                     /db_xref="GeneID:12688637"
     CDS             complement(78079..79062)
                     /gene="thiB"
                     /locus_tag="ECOK1_0069"
                     /note="identified by similarity to SP:P31550; match to
                     protein family HMM PF01547; match to protein family HMM
                     TIGR01254; match to protein family HMM TIGR01276"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter,
                     periplasmic thiamine/thiamine pyrophospate-binding
                     protein"
                     /protein_id="YP_006099324.1"
                     /db_xref="GI:386597818"
                     /db_xref="GeneID:12688637"
                     /translation="MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTELFAKSGVA
                     AEAVNVPGGWNNDTFVPYDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYEDPRT
                     STPGLGLLLWMQKVYGDNAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHILEEKKDNYAATNFIEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIP
                     TGNWMYPVANVTLPAGFEQLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR"
     misc_feature    complement(78082..79026)
                     /gene="thiB"
                     /locus_tag="ECOK1_0069"
                     /note="thiamine transporter substrate binding subunit;
                     Provisional; Region: tbpA; PRK11205"
                     /db_xref="CDD:236883"
     gene            complement(79226..80881)
                     /gene="sgrR"
                     /locus_tag="ECOK1_0070"
                     /db_xref="GeneID:12688638"
     CDS             complement(79226..80881)
                     /gene="sgrR"
                     /locus_tag="ECOK1_0070"
                     /note="identified by similarity to SP:P33595; match to
                     protein family HMM PF00496"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transport-related sRNA regulator SgrR"
                     /protein_id="YP_006099325.1"
                     /db_xref="GI:386597819"
                     /db_xref="GeneID:12688638"
                     /translation="MPSARLQQQFIRLWQCCEGKSQETTLNELAALLSCSRRHMRTLL
                     NTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAT
                     VRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
                     NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIA
                     NIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRN
                     STNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEG
                     CYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHART
                     IKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIES
                     DIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVA
                     SKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
     misc_feature    complement(79229..80881)
                     /gene="sgrR"
                     /locus_tag="ECOK1_0070"
                     /note="transcriptional regulator SgrR; Provisional;
                     Region: PRK13626"
                     /db_xref="CDD:184188"
     misc_feature    complement(80528..80869)
                     /gene="sgrR"
                     /locus_tag="ECOK1_0070"
                     /note="Sugar transport-related sRNA regulator N-term;
                     Region: SgrR_N; pfam12793"
                     /db_xref="CDD:193269"
     misc_feature    complement(79241..80536)
                     /gene="sgrR"
                     /locus_tag="ECOK1_0070"
                     /note="The C-terminal solute-binding domain of DNA-binding
                     transcriptional regulator SgrR is related to the ABC-type
                     oligopeptide-binding proteins and contains the type 2
                     periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507"
                     /db_xref="CDD:173872"
     gene            80970..81101
                     /locus_tag="ECOK1_0071"
                     /db_xref="GeneID:12688639"
     CDS             80970..81101
                     /locus_tag="ECOK1_0071"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099326.1"
                     /db_xref="GI:386597820"
                     /db_xref="GeneID:12688639"
                     /translation="MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEELMQWEGSHSDY"
     gene            complement(81209..81814)
                     /gene="leuD"
                     /locus_tag="ECOK1_0072"
                     /db_xref="GeneID:12688640"
     CDS             complement(81209..81814)
                     /gene="leuD"
                     /locus_tag="ECOK1_0072"
                     /EC_number="4.2.1.33"
                     /note="identified by similarity to SP:P30126; match to
                     protein family HMM PF00694; match to protein family HMM
                     TIGR00171"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="YP_006099327.1"
                     /db_xref="GI:386597821"
                     /db_xref="GeneID:12688640"
                     /translation="MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
                     RFTIDAFRRHCMMNGLDSIGLTLQHDDAIASYEEKQPAFMR"
     misc_feature    complement(81371..81772)
                     /gene="leuD"
                     /locus_tag="ECOK1_0072"
                     /note="Aconatase-like swivel domain of 3-isopropylmalate
                     dehydratase and related uncharacterized proteins.
                     3-isopropylmalate dehydratase catalyzes the isomerization
                     between 2-isopropylmalate and 3-isopropylmalate, via the
                     formation of 2-isopropylmaleate...; Region: IPMI_Swivel;
                     cd01577"
                     /db_xref="CDD:238809"
     misc_feature    complement(81557..81565)
                     /gene="leuD"
                     /locus_tag="ECOK1_0072"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238809"
     gene            complement(81825..83225)
                     /gene="leuC"
                     /locus_tag="ECOK1_0073"
                     /db_xref="GeneID:12688641"
     CDS             complement(81825..83225)
                     /gene="leuC"
                     /locus_tag="ECOK1_0073"
                     /EC_number="4.2.1.33"
                     /note="identified by match to protein family HMM PF00330;
                     match to protein family HMM TIGR00170"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="YP_006099328.1"
                     /db_xref="GI:386597822"
                     /db_xref="GeneID:12688641"
                     /translation="MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGL
                     RAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTV
                     VTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPL
                     TEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
                     KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
                     AAAAVTGHFADIRNIK"
     misc_feature    complement(81849..83141)
                     /gene="leuC"
                     /locus_tag="ECOK1_0073"
                     /note="3-isopropylmalate dehydratase catalyzes the
                     isomerization between 2-isopropylmalate and
                     3-isopropylmalate; Region: IPMI; cd01583"
                     /db_xref="CDD:153133"
     misc_feature    complement(order(81921..81923,81936..81938,81993..81995,
                     82839..82844,83118..83120,83127..83129))
                     /gene="leuC"
                     /locus_tag="ECOK1_0073"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:153133"
     misc_feature    complement(order(81939..81941,81993..81998,82005..82007,
                     82185..82187,82836..82838))
                     /gene="leuC"
                     /locus_tag="ECOK1_0073"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:153133"
     gene            complement(83228..84319)
                     /gene="leuB"
                     /locus_tag="ECOK1_0074"
                     /db_xref="GeneID:12688642"
     CDS             complement(83228..84319)
                     /gene="leuB"
                     /locus_tag="ECOK1_0074"
                     /EC_number="1.1.1.85"
                     /note="identified by similarity to SP:P30125; match to
                     protein family HMM PF00180; match to protein family HMM
                     TIGR00169"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="YP_006099329.1"
                     /db_xref="GI:386597823"
                     /db_xref="GeneID:12688642"
                     /translation="MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYD
                     VGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPD
                     VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAASAIERAINRALEEGI
                     RTGDLARGAAAVSTDEMGDIIARYVAEGV"
     misc_feature    complement(83234..84313)
                     /gene="leuB"
                     /locus_tag="ECOK1_0074"
                     /note="3-isopropylmalate dehydrogenase; Provisional;
                     Region: PRK00772"
                     /db_xref="CDD:234832"
     gene            complement(84319..85890)
                     /gene="leuA"
                     /locus_tag="ECOK1_0075"
                     /db_xref="GeneID:12688643"
     CDS             complement(84319..85890)
                     /gene="leuA"
                     /locus_tag="ECOK1_0075"
                     /EC_number="2.3.3.13"
                     /note="identified by match to protein family HMM PF00682;
                     match to protein family HMM PF08502; match to protein
                     family HMM TIGR00973"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="YP_006099330.1"
                     /db_xref="GI:386597824"
                     /db_xref="GeneID:12688643"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
                     AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFR
                     LDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYS
                     LTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
                     LQRKAQHNENNKETV"
     misc_feature    complement(84355..85890)
                     /gene="leuA"
                     /locus_tag="ECOK1_0075"
                     /note="2-isopropylmalate synthase; Validated; Region:
                     PRK00915"
                     /db_xref="CDD:234864"
     misc_feature    complement(85066..85872)
                     /gene="leuA"
                     /locus_tag="ECOK1_0075"
                     /note="2-isopropylmalate synthase (IPMS), N-terminal
                     catalytic TIM barrel domain; Region: DRE_TIM_IPMS;
                     cd07940"
                     /db_xref="CDD:163678"
     misc_feature    complement(order(85279..85281,85285..85287,85378..85380,
                     85384..85386,85468..85470,85474..85476,85600..85602,
                     85666..85668,85759..85761,85840..85842,85849..85854))
                     /gene="leuA"
                     /locus_tag="ECOK1_0075"
                     /note="active site"
                     /db_xref="CDD:163678"
     misc_feature    complement(order(85759..85761,85849..85854))
                     /gene="leuA"
                     /locus_tag="ECOK1_0075"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:163678"
     misc_feature    complement(order(85279..85281,85285..85287))
                     /gene="leuA"
                     /locus_tag="ECOK1_0075"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163678"
     misc_feature    complement(84394..84786)
                     /gene="leuA"
                     /locus_tag="ECOK1_0075"
                     /note="LeuA allosteric (dimerisation) domain; Region:
                     LeuA_dimer; smart00917"
                     /db_xref="CDD:214910"
     gene            complement(85982..86068)
                     /gene="leuL"
                     /locus_tag="ECOK1_0076"
                     /db_xref="GeneID:12688644"
     CDS             complement(85982..86068)
                     /gene="leuL"
                     /locus_tag="ECOK1_0076"
                     /note="identified by match to protein family HMM PF08054"
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="YP_006099331.1"
                     /db_xref="GI:386597825"
                     /db_xref="GeneID:12688644"
                     /translation="MTHIVRFIGLLLLNASFLRGRRVSGIQH"
     misc_feature    complement(85985..86068)
                     /gene="leuL"
                     /locus_tag="ECOK1_0076"
                     /note="leu operon leader peptide; Provisional; Region:
                     PRK09925"
                     /db_xref="CDD:137592"
     gene            86726..87670
                     /gene="leuO"
                     /locus_tag="ECOK1_0077"
                     /db_xref="GeneID:12688645"
     CDS             86726..87670
                     /gene="leuO"
                     /locus_tag="ECOK1_0077"
                     /note="identified by similarity to SP:P10151; match to
                     protein family HMM PF00126; match to protein family HMM
                     PF03466"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LeuO"
                     /protein_id="YP_006099332.1"
                     /db_xref="GI:386597826"
                     /db_xref="GeneID:12688645"
                     /translation="MPEVQTDHPETAELSKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     ALGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
                     ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDR
                     FASFSQTWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVL
                     PLPLKQNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR"
     misc_feature    86726..87667
                     /gene="leuO"
                     /locus_tag="ECOK1_0077"
                     /note="leucine transcriptional activator; Reviewed;
                     Region: leuO; PRK09508"
                     /db_xref="CDD:181918"
     misc_feature    86795..86971
                     /gene="leuO"
                     /locus_tag="ECOK1_0077"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    87062..87658
                     /gene="leuO"
                     /locus_tag="ECOK1_0077"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulator LeuO, an activator of
                     leucine synthesis operon, contains the type 2 periplasmic
                     binding fold; Region: PBP2_LeuO; cd08466"
                     /db_xref="CDD:176155"
     misc_feature    order(87080..87082,87086..87091,87101..87103,87275..87277,
                     87383..87385,87584..87586)
                     /gene="leuO"
                     /locus_tag="ECOK1_0077"
                     /note="putative substrate binding pocket [chemical
                     binding]; other site"
                     /db_xref="CDD:176155"
     misc_feature    order(87083..87085,87092..87097,87104..87109,87116..87121,
                     87125..87130,87137..87142,87146..87160,87164..87166,
                     87353..87355,87434..87448,87455..87460,87467..87472,
                     87479..87481,87521..87523)
                     /gene="leuO"
                     /locus_tag="ECOK1_0077"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176155"
     gene            87988..89712
                     /gene="ilvI"
                     /locus_tag="ECOK1_0078"
                     /db_xref="GeneID:12688646"
     CDS             87988..89712
                     /gene="ilvI"
                     /locus_tag="ECOK1_0078"
                     /EC_number="2.2.1.6"
                     /note="identified by similarity to SP:P00893; match to
                     protein family HMM PF00205; match to protein family HMM
                     PF02775; match to protein family HMM PF02776; match to
                     protein family HMM TIGR00118"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase, large subunit, isozyme
                     III"
                     /protein_id="YP_006099333.1"
                     /db_xref="GI:386597827"
                     /db_xref="GeneID:12688646"
                     /translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGID
                     HVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
                     LPKDILNPANKLPYVWPESVSMRSYNPTTSGHKGQIKRALQTLVAAKKPVVYVGGGAI
                     TAGCHLQLKEAVEVLNLPVVSSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVI
                     FAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLEL
                     LSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTHGDAYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGS
                     IQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGIQISHPQELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     misc_feature    87988..89709
                     /gene="ilvI"
                     /locus_tag="ECOK1_0078"
                     /note="acetolactate synthase 3 catalytic subunit;
                     Validated; Region: PRK07979"
                     /db_xref="CDD:181185"
     misc_feature    88009..88476
                     /gene="ilvI"
                     /locus_tag="ECOK1_0078"
                     /note="Pyrimidine (PYR) binding domain of POX and related
                     proteins; Region: TPP_PYR_POX_like; cd07035"
                     /db_xref="CDD:132918"
     misc_feature    order(88048..88050,88063..88068,88078..88080,88090..88092,
                     88117..88137,88144..88146,88153..88158,88165..88170,
                     88174..88182,88216..88218,88237..88239,88249..88251,
                     88258..88263)
                     /gene="ilvI"
                     /locus_tag="ECOK1_0078"
                     /note="PYR/PP interface [polypeptide binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    order(88063..88071,88078..88080,88090..88092,88120..88122,
                     88126..88137,88141..88143,88216..88218,88225..88230,
                     88234..88239,88246..88248,88348..88350,88357..88359)
                     /gene="ilvI"
                     /locus_tag="ECOK1_0078"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    order(88063..88065,88138..88140,88216..88218,88228..88230)
                     /gene="ilvI"
                     /locus_tag="ECOK1_0078"
                     /note="TPP binding site [chemical binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    88573..88980
                     /gene="ilvI"
                     /locus_tag="ECOK1_0078"
                     /note="Thiamine pyrophosphate enzyme, central domain;
                     Region: TPP_enzyme_M; pfam00205"
                     /db_xref="CDD:249676"
     misc_feature    89101..89655
                     /gene="ilvI"
                     /locus_tag="ECOK1_0078"
                     /note="Thiamine pyrophosphate (TPP) family,
                     Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding
                     module; composed of proteins similar to the large
                     catalytic subunit of AHAS. AHAS catalyzes the condensation
                     of two molecules of pyruvate to give the...; Region:
                     TPP_AHAS; cd02015"
                     /db_xref="CDD:238973"
     misc_feature    order(89170..89181,89248..89250,89254..89256,89329..89337,
                     89344..89346,89410..89412)
                     /gene="ilvI"
                     /locus_tag="ECOK1_0078"
                     /note="TPP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238973"
     misc_feature    order(89239..89241,89248..89250,89254..89256,89341..89346,
                     89350..89355,89374..89376,89491..89496,89506..89508,
                     89515..89517)
                     /gene="ilvI"
                     /locus_tag="ECOK1_0078"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238973"
     gene            89715..90206
                     /gene="ilvH"
                     /locus_tag="ECOK1_0079"
                     /db_xref="GeneID:12688647"
     CDS             89715..90206
                     /gene="ilvH"
                     /locus_tag="ECOK1_0079"
                     /EC_number="2.2.1.6"
                     /note="identified by similarity to SP:P00894; match to
                     protein family HMM PF01842; match to protein family HMM
                     TIGR00119"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase, small subunit, isozyme
                     III"
                     /protein_id="YP_006099334.1"
                     /db_xref="GI:386597828"
                     /db_xref="GeneID:12688647"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVK
                     RNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
                     IMR"
     misc_feature    89715..90200
                     /gene="ilvH"
                     /locus_tag="ECOK1_0079"
                     /note="acetolactate synthase 3 regulatory subunit;
                     Reviewed; Region: ilvH; PRK11895"
                     /db_xref="CDD:183365"
     misc_feature    89721..89936
                     /gene="ilvH"
                     /locus_tag="ECOK1_0079"
                     /note="N-terminal ACT domain of the Escherichia coli
                     IlvH-like regulatory subunit of acetohydroxyacid synthase
                     (AHAS); Region: ACT_AHAS; cd04878"
                     /db_xref="CDD:153150"
     misc_feature    order(89739..89741,89745..89747,89760..89762,89799..89804,
                     89817..89819,89844..89846)
                     /gene="ilvH"
                     /locus_tag="ECOK1_0079"
                     /note="putative valine binding site [chemical binding];
                     other site"
                     /db_xref="CDD:153150"
     misc_feature    order(89751..89756,89763..89765,89784..89786,89793..89795,
                     89805..89819,89847..89849)
                     /gene="ilvH"
                     /locus_tag="ECOK1_0079"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:153150"
     misc_feature    89961..90188
                     /gene="ilvH"
                     /locus_tag="ECOK1_0079"
                     /note="Small subunit of acetolactate synthase; Region:
                     ALS_ss_C; pfam10369"
                     /db_xref="CDD:255942"
     gene            90218..90304
                     /locus_tag="ECOK1_0080"
                     /db_xref="GeneID:12688648"
     CDS             90218..90304
                     /locus_tag="ECOK1_0080"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical fruR leader peptide"
                     /protein_id="YP_006099335.1"
                     /db_xref="GI:386597829"
                     /db_xref="GeneID:12688648"
                     /translation="MRNLQPNMSRWAFFAKSVGTWNKSSCRS"
     gene            90386..91390
                     /gene="fruR"
                     /locus_tag="ECOK1_0081"
                     /db_xref="GeneID:12688649"
     CDS             90386..91390
                     /gene="fruR"
                     /locus_tag="ECOK1_0081"
                     /note="identified by similarity to SP:P0ACP1; match to
                     protein family HMM PF00356; match to protein family HMM
                     PF00532; match to protein family HMM TIGR02417"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose repressor"
                     /protein_id="YP_006099336.1"
                     /db_xref="GI:386597830"
                     /db_xref="GeneID:12688649"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDN
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
                     "
     misc_feature    90386..91369
                     /gene="fruR"
                     /locus_tag="ECOK1_0081"
                     /note="DNA-binding transcriptional regulator FruR;
                     Provisional; Region: PRK11303"
                     /db_xref="CDD:236897"
     misc_feature    90398..90559
                     /gene="fruR"
                     /locus_tag="ECOK1_0081"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(90419..90433,90437..90442,90449..90451,90473..90478,
                     90485..90487,90524..90526,90533..90535,90542..90547,
                     90551..90556)
                     /gene="fruR"
                     /locus_tag="ECOK1_0081"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    90524..90553
                     /gene="fruR"
                     /locus_tag="ECOK1_0081"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    90572..91363
                     /gene="fruR"
                     /locus_tag="ECOK1_0081"
                     /note="Ligand binding domain of DNA transcription
                     repressor specific for fructose (FruR) and its close
                     homologs; Region: PBP1_FruR; cd06274"
                     /db_xref="CDD:107269"
     misc_feature    order(90596..90598,90626..90631,90635..90640,90647..90649,
                     90662..90664,90671..90673,90677..90679,90731..90733,
                     91136..91138,91226..91228,91232..91234)
                     /gene="fruR"
                     /locus_tag="ECOK1_0081"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107269"
     misc_feature    order(90608..90610,90620..90622,90821..90826,90857..90868,
                     90974..90976,91121..91123,91205..91207)
                     /gene="fruR"
                     /locus_tag="ECOK1_0081"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107269"
     gene            91992..92450
                     /gene="mraZ"
                     /locus_tag="ECOK1_0082"
                     /db_xref="GeneID:12688650"
     CDS             91992..92450
                     /gene="mraZ"
                     /locus_tag="ECOK1_0082"
                     /note="identified by similarity to GB:AAN78597.1; match to
                     protein family HMM PF02381; match to protein family HMM
                     TIGR00242"
                     /codon_start=1
                     /transl_table=11
                     /product="MraZ protein"
                     /protein_id="YP_006099337.1"
                     /db_xref="GI:386597831"
                     /db_xref="GeneID:12688650"
                     /translation="MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL"
     misc_feature    91992..92444
                     /gene="mraZ"
                     /locus_tag="ECOK1_0082"
                     /note="mraZ protein; Region: TIGR00242"
                     /db_xref="CDD:129345"
     misc_feature    91992..92219
                     /gene="mraZ"
                     /locus_tag="ECOK1_0082"
                     /note="MraZ protein; Region: MraZ; pfam02381"
                     /db_xref="CDD:111290"
     misc_feature    92220..92396
                     /gene="mraZ"
                     /locus_tag="ECOK1_0082"
                     /note="MraZ protein; Region: MraZ; pfam02381"
                     /db_xref="CDD:111290"
     gene            92452..93393
                     /gene="mraW"
                     /locus_tag="ECOK1_0083"
                     /db_xref="GeneID:12688651"
     CDS             92452..93393
                     /gene="mraW"
                     /locus_tag="ECOK1_0083"
                     /EC_number="2.1.1.-"
                     /note="identified by match to protein family HMM PF01795;
                     match to protein family HMM TIGR00006"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-methyltransferase MraW"
                     /protein_id="YP_006099338.1"
                     /db_xref="GI:386597832"
                     /db_xref="GeneID:12688651"
                     /translation="MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
                     AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKL
                     GGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA"
     misc_feature    92464..93387
                     /gene="mraW"
                     /locus_tag="ECOK1_0083"
                     /note="16S rRNA m(4)C1402 methyltranserfase; Provisional;
                     Region: PRK00050"
                     /db_xref="CDD:234597"
     gene            93390..93755
                     /gene="ftsL"
                     /locus_tag="ECOK1_0084"
                     /db_xref="GeneID:12688652"
     CDS             93390..93755
                     /gene="ftsL"
                     /locus_tag="ECOK1_0084"
                     /note="identified by similarity to SP:P22187; match to
                     protein family HMM PF04999; match to protein family HMM
                     TIGR02209"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="YP_006099339.1"
                     /db_xref="GI:386597833"
                     /db_xref="GeneID:12688652"
                     /translation="MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     misc_feature    93438..93752
                     /gene="ftsL"
                     /locus_tag="ECOK1_0084"
                     /note="cell division protein FtsL; Provisional; Region:
                     PRK10772"
                     /db_xref="CDD:182717"
     gene            93771..95537
                     /gene="ftsI"
                     /locus_tag="ECOK1_0085"
                     /db_xref="GeneID:12688653"
     CDS             93771..95537
                     /gene="ftsI"
                     /locus_tag="ECOK1_0085"
                     /EC_number="2.4.1.129"
                     /note="identified by similarity to SP:P0AD68; match to
                     protein family HMM PF00905; match to protein family HMM
                     PF03717"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan synthetase FtsI"
                     /protein_id="YP_006099340.1"
                     /db_xref="GI:386597834"
                     /db_xref="GeneID:12688653"
                     /translation="MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAW
                     LQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSQAAHNLTLSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTVPY
                     RINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLG
                     LVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVD
                     PPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYI
                     NKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPD
                     ALTTGDKNEFVINQGEGTGGRS"
     misc_feature    93774..95507
                     /gene="ftsI"
                     /locus_tag="ECOK1_0085"
                     /note="peptidoglycan synthase FtsI; Provisional; Region:
                     PRK15105"
                     /db_xref="CDD:185060"
     misc_feature    93981..94436
                     /gene="ftsI"
                     /locus_tag="ECOK1_0085"
                     /note="Penicillin-binding Protein dimerization domain;
                     Region: PBP_dimer; pfam03717"
                     /db_xref="CDD:252119"
     misc_feature    94548..95432
                     /gene="ftsI"
                     /locus_tag="ECOK1_0085"
                     /note="Penicillin binding protein transpeptidase domain;
                     Region: Transpeptidase; pfam00905"
                     /db_xref="CDD:250215"
     gene            95524..97011
                     /gene="murE"
                     /locus_tag="ECOK1_0086"
                     /db_xref="GeneID:12688654"
     CDS             95524..97011
                     /gene="murE"
                     /locus_tag="ECOK1_0086"
                     /EC_number="6.3.2.13"
                     /note="identified by similarity to SP:P22188; match to
                     protein family HMM PF01225; match to protein family HMM
                     PF02875; match to protein family HMM PF08245; match to
                     protein family HMM TIGR01085"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="YP_006099341.1"
                     /db_xref="GI:386597835"
                     /db_xref="GeneID:12688654"
                     /translation="MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFY
                     HEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
                     EHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKA
                     TDVNYHDSGATIRFSSSWGDGEIESRLMGAFNVSNLLLALATLLALGYPLADLLKTAA
                     RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGYAKVMEGRAEAVTC
                     AVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA"
     misc_feature    95524..97005
                     /gene="murE"
                     /locus_tag="ECOK1_0086"
                     /note="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase; Provisional; Region: murE;
                     PRK00139"
                     /db_xref="CDD:234660"
     misc_feature    95596..95829
                     /gene="murE"
                     /locus_tag="ECOK1_0086"
                     /note="Mur ligase family, catalytic domain; Region:
                     Mur_ligase; pfam01225"
                     /db_xref="CDD:250458"
     misc_feature    95914..96456
                     /gene="murE"
                     /locus_tag="ECOK1_0086"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:254689"
     misc_feature    96538..96798
                     /gene="murE"
                     /locus_tag="ECOK1_0086"
                     /note="Mur ligase family, glutamate ligase domain; Region:
                     Mur_ligase_C; pfam02875"
                     /db_xref="CDD:251584"
     gene            97008..98366
                     /gene="murF"
                     /locus_tag="ECOK1_0087"
                     /db_xref="GeneID:12688655"
     CDS             97008..98366
                     /gene="murF"
                     /locus_tag="ECOK1_0087"
                     /EC_number="6.3.2.10"
                     /note="identified by similarity to SP:P11880; match to
                     protein family HMM PF01225; match to protein family HMM
                     PF02875; match to protein family HMM PF08245; match to
                     protein family HMM TIGR01143"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="YP_006099342.1"
                     /db_xref="GI:386597836"
                     /db_xref="GeneID:12688655"
                     /translation="MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALK
                     GERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARV
                     VALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELG
                     ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMN
                     ADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP
                     LPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIKLAENQLLLDDSYN
                     ANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGIDCVLSVGK
                     QSHAISTASGVGEHFSDKTALIARLKSLIAEQQVITILVKGSRSAAMEEVVRALQENG
                     TC"
     misc_feature    97008..98363
                     /gene="murF"
                     /locus_tag="ECOK1_0087"
                     /note="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine
                     ligase; Reviewed; Region: murF; PRK10773"
                     /db_xref="CDD:182718"
     misc_feature    97086..97292
                     /gene="murF"
                     /locus_tag="ECOK1_0087"
                     /note="Mur ligase family, catalytic domain; Region:
                     Mur_ligase; pfam01225"
                     /db_xref="CDD:250458"
     misc_feature    97323..97856
                     /gene="murF"
                     /locus_tag="ECOK1_0087"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:254689"
     misc_feature    97944..98171
                     /gene="murF"
                     /locus_tag="ECOK1_0087"
                     /note="Mur ligase family, glutamate ligase domain; Region:
                     Mur_ligase_C; pfam02875"
                     /db_xref="CDD:251584"
     gene            98360..99442
                     /gene="mraY"
                     /locus_tag="ECOK1_0088"
                     /db_xref="GeneID:12688656"
     CDS             98360..99442
                     /gene="mraY"
                     /locus_tag="ECOK1_0088"
                     /EC_number="2.7.8.13"
                     /note="identified by match to protein family HMM PF00953;
                     match to protein family HMM TIGR00445"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="YP_006099343.1"
                     /db_xref="GI:386597837"
                     /db_xref="GeneID:12688656"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQL
                     VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWA
                     TGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     misc_feature    98540..99427
                     /gene="mraY"
                     /locus_tag="ECOK1_0088"
                     /note="Phospho-N-acetylmuramoyl-pentapeptide-transferase
                     (mraY) is an enzyme responsible for the formation of the
                     first lipid intermediate in the synthesis of bacterial
                     cell wall peptidoglycan. It catalyzes the formation of...;
                     Region: GT_MraY; cd06852"
                     /db_xref="CDD:133462"
     misc_feature    98702..98707
                     /gene="mraY"
                     /locus_tag="ECOK1_0088"
                     /note="Mg++ binding site [ion binding]; other site"
                     /db_xref="CDD:133462"
     misc_feature    99149..99160
                     /gene="mraY"
                     /locus_tag="ECOK1_0088"
                     /note="putative catalytic motif [active]"
                     /db_xref="CDD:133462"
     misc_feature    order(99308..99310,99326..99340)
                     /gene="mraY"
                     /locus_tag="ECOK1_0088"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:133462"
     gene            99445..100761
                     /gene="murD"
                     /locus_tag="ECOK1_0089"
                     /db_xref="GeneID:12688657"
     CDS             99445..100761
                     /gene="murD"
                     /locus_tag="ECOK1_0089"
                     /EC_number="6.3.2.9"
                     /note="identified by similarity to SP:P14900; match to
                     protein family HMM PF02875; match to protein family HMM
                     PF08245; match to protein family HMM TIGR01087"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanine--D-glutamate ligase"
                     /protein_id="YP_006099344.1"
                     /db_xref="GI:386597838"
                     /db_xref="GeneID:12688657"
                     /translation="MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGL
                     DKLPEAVERHTGGLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELS
                     SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALT
                     MPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWVNDSKATNVGSTEAALNGL
                     HVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETME
                     QAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG"
     misc_feature    99445..100758
                     /gene="murD"
                     /locus_tag="ECOK1_0089"
                     /note="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
                     synthetase; Provisional; Region: murD; PRK03806"
                     /db_xref="CDD:179651"
     misc_feature    99772..100260
                     /gene="murD"
                     /locus_tag="ECOK1_0089"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:254689"
     misc_feature    100345..100563
                     /gene="murD"
                     /locus_tag="ECOK1_0089"
                     /note="Mur ligase family, glutamate ligase domain; Region:
                     Mur_ligase_C; pfam02875"
                     /db_xref="CDD:251584"
     gene            100761..102005
                     /gene="ftsW"
                     /locus_tag="ECOK1_0090"
                     /db_xref="GeneID:12688658"
     CDS             100761..102005
                     /gene="ftsW"
                     /locus_tag="ECOK1_0090"
                     /note="identified by similarity to SP:P0ABG4; match to
                     protein family HMM PF01098; match to protein family HMM
                     TIGR02614"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="YP_006099345.1"
                     /db_xref="GI:386597839"
                     /db_xref="GeneID:12688658"
                     /translation="MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMY
                     DRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRL
                     PMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
                     ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVVLLILAEPYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGEL
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     MLLRIDYETRLEKAQAFVRGSR"
     misc_feature    100791..102002
                     /gene="ftsW"
                     /locus_tag="ECOK1_0090"
                     /note="cell division protein FtsW; Provisional; Region:
                     PRK10774"
                     /db_xref="CDD:182719"
     gene            102002..103069
                     /gene="murG"
                     /locus_tag="ECOK1_0091"
                     /db_xref="GeneID:12688659"
     CDS             102002..103069
                     /gene="murG"
                     /locus_tag="ECOK1_0091"
                     /EC_number="2.4.1.227"
                     /note="identified by match to protein family HMM PF03033;
                     match to protein family HMM PF04101; match to protein
                     family HMM TIGR01133"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="YP_006099346.1"
                     /db_xref="GI:386597840"
                     /db_xref="GeneID:12688659"
                     /translation="MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADR
                     MEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQS
                     GKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPA
                     LFVPFQHKDRQQYWNALPLEKAGAAKIIEQSQLSVDAVANTLAGWSREILLTMAERAR
                     AASIPDATERVANEVSRAARA"
     misc_feature    102017..103066
                     /gene="murG"
                     /locus_tag="ECOK1_0091"
                     /note="undecaprenyldiphospho-muramoylpentapeptide beta-N-
                     acetylglucosaminyltransferase; Provisional; Region: murG;
                     PRK00726"
                     /db_xref="CDD:234825"
     misc_feature    102020..103045
                     /gene="murG"
                     /locus_tag="ECOK1_0091"
                     /note="MurG is an N-acetylglucosaminyltransferase, the
                     last enzyme involved in the intracellular phase of
                     peptidoglycan biosynthesis. It transfers
                     N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4
                     hydroxyl of a lipid-linked N-acetylmuramoyl
                     pentapeptide...; Region: GT1_MurG; cd03785"
                     /db_xref="CDD:99961"
     misc_feature    order(102050..102052,102380..102382,102572..102574,
                     102650..102652,102728..102730,102740..102742,
                     102785..102796,102803..102805,102842..102844,
                     102860..102865,102872..102874)
                     /gene="murG"
                     /locus_tag="ECOK1_0091"
                     /note="active site"
                     /db_xref="CDD:99961"
     misc_feature    order(102221..102223,102230..102232,102263..102265,
                     102347..102349,102422..102424)
                     /gene="murG"
                     /locus_tag="ECOK1_0091"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99961"
     gene            103123..104598
                     /gene="murC"
                     /locus_tag="ECOK1_0092"
                     /db_xref="GeneID:12688660"
     CDS             103123..104598
                     /gene="murC"
                     /locus_tag="ECOK1_0092"
                     /EC_number="6.3.2.8"
                     /note="identified by match to protein family HMM PF01225;
                     match to protein family HMM PF02875; match to protein
                     family HMM PF08245; match to protein family HMM TIGR01082"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="YP_006099347.1"
                     /db_xref="GI:386597841"
                     /db_xref="GeneID:12688660"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYD
                     DFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEML
                     APVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD"
     misc_feature    103159..104574
                     /gene="murC"
                     /locus_tag="ECOK1_0092"
                     /note="UDP-N-acetylmuramate--L-alanine ligase;
                     Provisional; Region: murC; PRK00421"
                     /db_xref="CDD:234757"
     misc_feature    103183..103482
                     /gene="murC"
                     /locus_tag="ECOK1_0092"
                     /note="Mur ligase family, catalytic domain; Region:
                     Mur_ligase; pfam01225"
                     /db_xref="CDD:250458"
     misc_feature    103492..104007
                     /gene="murC"
                     /locus_tag="ECOK1_0092"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:254689"
     misc_feature    104128..104382
                     /gene="murC"
                     /locus_tag="ECOK1_0092"
                     /note="Mur ligase family, glutamate ligase domain; Region:
                     Mur_ligase_C; pfam02875"
                     /db_xref="CDD:251584"
     gene            104591..105511
                     /gene="ddlB"
                     /locus_tag="ECOK1_0093"
                     /db_xref="GeneID:12688661"
     CDS             104591..105511
                     /gene="ddlB"
                     /locus_tag="ECOK1_0093"
                     /EC_number="6.3.2.4"
                     /note="identified by similarity to SP:P07862; match to
                     protein family HMM PF01820; match to protein family HMM
                     PF07478; match to protein family HMM TIGR01205"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="YP_006099348.1"
                     /db_xref="GI:386597842"
                     /db_xref="GeneID:12688661"
                     /translation="MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE
                     VDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKL
                     LWQGAGLPVAPWVALTRAEFEKGLNDKQLAEISSLGLPVIVKPSREGSSVGMSKVVAE
                     NALQDALRLAFQHDEEVLIEKWLSGPEFTIAILGEEILPSIRIQPAGTFYDYEAKYLS
                     DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     misc_feature    104591..105508
                     /gene="ddlB"
                     /locus_tag="ECOK1_0093"
                     /note="D-alanine--D-alanine ligase; Reviewed; Region: ddl;
                     PRK01372"
                     /db_xref="CDD:234948"
     misc_feature    104600..104848
                     /gene="ddlB"
                     /locus_tag="ECOK1_0093"
                     /note="D-ala D-ala ligase N-terminus; Region:
                     Dala_Dala_lig_N; pfam01820"
                     /db_xref="CDD:250892"
     misc_feature    104897..105499
                     /gene="ddlB"
                     /locus_tag="ECOK1_0093"
                     /note="D-ala D-ala ligase C-terminus; Region:
                     Dala_Dala_lig_C; pfam07478"
                     /db_xref="CDD:254223"
     gene            105513..106343
                     /gene="ftsQ"
                     /locus_tag="ECOK1_0094"
                     /db_xref="GeneID:12688662"
     CDS             105513..106343
                     /gene="ftsQ"
                     /locus_tag="ECOK1_0094"
                     /note="identified by similarity to SP:P06136; match to
                     protein family HMM PF03799; match to protein family HMM
                     PF08478"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="YP_006099349.1"
                     /db_xref="GI:386597843"
                     /db_xref="GeneID:12688662"
                     /translation="MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWV
                     VLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQR
                     LPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPDRTSKQVLPML
                     YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
                     "
     misc_feature    105513..106304
                     /gene="ftsQ"
                     /locus_tag="ECOK1_0094"
                     /note="cell division protein FtsQ; Provisional; Region:
                     PRK10775"
                     /db_xref="CDD:182720"
     misc_feature    105681..105890
                     /gene="ftsQ"
                     /locus_tag="ECOK1_0094"
                     /note="POTRA domain, FtsQ-type; Region: POTRA_1;
                     pfam08478"
                     /db_xref="CDD:254821"
     misc_feature    105897..106253
                     /gene="ftsQ"
                     /locus_tag="ECOK1_0094"
                     /note="Cell division protein FtsQ; Region: FtsQ;
                     pfam03799"
                     /db_xref="CDD:252171"
     gene            106340..107602
                     /gene="ftsA"
                     /locus_tag="ECOK1_0095"
                     /db_xref="GeneID:12688663"
     CDS             106340..107602
                     /gene="ftsA"
                     /locus_tag="ECOK1_0095"
                     /note="identified by similarity to SP:P0ABH0; match to
                     protein family HMM PF02491; match to protein family HMM
                     TIGR01174"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="YP_006099350.1"
                     /db_xref="GI:386597844"
                     /db_xref="GeneID:12688663"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     misc_feature    106340..107599
                     /gene="ftsA"
                     /locus_tag="ECOK1_0095"
                     /note="cell division protein FtsA; Reviewed; Region: ftsA;
                     PRK09472"
                     /db_xref="CDD:181887"
     misc_feature    106640..>107023
                     /gene="ftsA"
                     /locus_tag="ECOK1_0095"
                     /note="Nucleotide-Binding Domain of the sugar
                     kinase/HSP70/actin superfamily; Region:
                     NBD_sugar-kinase_HSP70_actin; cd00012"
                     /db_xref="CDD:212657"
     misc_feature    106955..107416
                     /gene="ftsA"
                     /locus_tag="ECOK1_0095"
                     /note="Cell division protein FtsA; Region: FtsA;
                     pfam14450"
                     /db_xref="CDD:258601"
     STS             106891..107127
                     /gene="ftsA"
                     /locus_tag="ECOK1_0095"
                     /standard_name="G34047"
                     /db_xref="UniSTS:10389"
     gene            107663..108814
                     /gene="ftsZ"
                     /locus_tag="ECOK1_0096"
                     /db_xref="GeneID:12688664"
     CDS             107663..108814
                     /gene="ftsZ"
                     /locus_tag="ECOK1_0096"
                     /note="identified by similarity to SP:P0A9A6; match to
                     protein family HMM PF00091; match to protein family HMM
                     PF03953; match to protein family HMM TIGR00065"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="YP_006099351.1"
                     /db_xref="GI:386597845"
                     /db_xref="GeneID:12688664"
                     /translation="MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD"
     misc_feature    107732..108811
                     /gene="ftsZ"
                     /locus_tag="ECOK1_0096"
                     /note="cell division protein FtsZ; Validated; Region:
                     PRK09330"
                     /db_xref="CDD:236468"
     misc_feature    107732..108604
                     /gene="ftsZ"
                     /locus_tag="ECOK1_0096"
                     /note="FtsZ is a GTPase that is similar to the eukaryotic
                     tubulins and is essential for cell division in
                     prokaryotes.  FtsZ is capable of polymerizing in a
                     GTP-driven process into structures similar to those formed
                     by tubulin. FtsZ forms a ring-shaped septum at...; Region:
                     FtsZ_type1; cd02201"
                     /db_xref="CDD:100021"
     misc_feature    order(107732..107734,107804..107806,107969..107989,
                     108062..108067,108086..108088,108155..108157,
                     108206..108208,108215..108220,108227..108229)
                     /gene="ftsZ"
                     /locus_tag="ECOK1_0096"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100021"
     misc_feature    order(108278..108283,108287..108289,108467..108478,
                     108485..108487)
                     /gene="ftsZ"
                     /locus_tag="ECOK1_0096"
                     /note="SulA interaction site; other site"
                     /db_xref="CDD:100021"
     misc_feature    <108680..108811
                     /gene="ftsZ"
                     /locus_tag="ECOK1_0096"
                     /note="cell division protein FtsZ, alphaProteobacterial
                     C-terminal extension; Region: FtsZ_alphas_C; TIGR03483"
                     /db_xref="CDD:234228"
     gene            108915..109832
                     /gene="lpxC"
                     /locus_tag="ECOK1_0097"
                     /db_xref="GeneID:12688665"
     CDS             108915..109832
                     /gene="lpxC"
                     /locus_tag="ECOK1_0097"
                     /EC_number="3.5.1.-"
                     /note="identified by match to protein family HMM PF03331;
                     match to protein family HMM TIGR00325"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
                     deacetylase"
                     /protein_id="YP_006099352.1"
                     /db_xref="GI:386597846"
                     /db_xref="GeneID:12688665"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTID
                     FNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEYVTFQDDAELPLAFKAPSAVLA"
     misc_feature    108915..109811
                     /gene="lpxC"
                     /locus_tag="ECOK1_0097"
                     /note="UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
                     deacetylase; Reviewed; Region: lpxC; PRK13186"
                     /db_xref="CDD:237294"
     misc_feature    108918..109754
                     /gene="lpxC"
                     /locus_tag="ECOK1_0097"
                     /note="UDP-3-O-acyl N-acetylglycosamine deacetylase;
                     Region: LpxC; pfam03331"
                     /db_xref="CDD:202596"
     gene            109988..110575
                     /gene="secM"
                     /locus_tag="ECOK1_0098"
                     /db_xref="GeneID:12688666"
     CDS             109988..110575
                     /gene="secM"
                     /locus_tag="ECOK1_0098"
                     /note="identified by similarity to SP:P62395; match to
                     protein family HMM PF06558"
                     /codon_start=1
                     /transl_table=11
                     /product="secretion monitor protein"
                     /protein_id="YP_006099353.1"
                     /db_xref="GI:386597847"
                     /db_xref="GeneID:12688666"
                     /translation="MLWTSGFNDKICALNTFEYDRDGNNVSGILTRWRQFGKRYFWPH
                     LLLGMVAASLGLPALSNAAEPNAPAKATTRNHEPSAKVNFGQLALLEANTRRPNSNYS
                     VDYWHQHAIRTVIRHLSFAMAPQTLPVAEESLPLQAQHLALLDTLSALLTQEGTPSEK
                     GYRIDYAHFTPQAKFSTPVWISQAQGIRAGPQRLS"
     misc_feature    110066..110572
                     /gene="secM"
                     /locus_tag="ECOK1_0098"
                     /note="SecA regulator SecM; Provisional; Region: PRK02943"
                     /db_xref="CDD:235088"
     gene            110637..113342
                     /gene="secA"
                     /locus_tag="ECOK1_0099"
                     /db_xref="GeneID:12688667"
     CDS             110637..113342
                     /gene="secA"
                     /locus_tag="ECOK1_0099"
                     /note="identified by match to protein family HMM PF01043;
                     match to protein family HMM PF02810; match to protein
                     family HMM PF07516; match to protein family HMM PF07517;
                     match to protein family HMM TIGR00963"
                     /codon_start=1
                     /transl_table=11
                     /product="Preprotein translocase subunit SecA"
                     /protein_id="YP_006099354.1"
                     /db_xref="GI:386597848"
                     /db_xref="GeneID:12688667"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELK
                     GKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEM
                     RTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE
                     RGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQ
                     PVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAG
                     RGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLAAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQ
                     LSYQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ"
     misc_feature    110640..113339
                     /gene="secA"
                     /locus_tag="ECOK1_0099"
                     /note="preprotein translocase subunit SecA; Reviewed;
                     Region: PRK12904"
                     /db_xref="CDD:237259"
     misc_feature    111318..111710
                     /gene="secA"
                     /locus_tag="ECOK1_0099"
                     /note="SecA preprotein cross-linking domain; Region:
                     SecA_PP_bind; smart00958"
                     /db_xref="CDD:214938"
     misc_feature    112485..113129
                     /gene="secA"
                     /locus_tag="ECOK1_0099"
                     /note="SecA Wing and Scaffold domain; Region: SecA_SW;
                     pfam07516"
                     /db_xref="CDD:254253"
     misc_feature    113277..113333
                     /gene="secA"
                     /locus_tag="ECOK1_0099"
                     /note="SEC-C motif; Region: SEC-C; pfam02810"
                     /db_xref="CDD:251544"
     gene            113402..113800
                     /gene="mutT"
                     /locus_tag="ECOK1_0100"
                     /db_xref="GeneID:12688668"
     CDS             113402..113800
                     /gene="mutT"
                     /locus_tag="ECOK1_0100"
                     /EC_number="3.6.1.-"
                     /note="identified by match to protein family HMM PF00293;
                     match to protein family HMM TIGR00586"
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="YP_006099355.1"
                     /db_xref="GI:386597849"
                     /db_xref="GeneID:12688668"
                     /translation="MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKVEMGE
                     TPEQAVVRELQEEVGITPQHFSLFEKLEYEFPDRHITLWFWLVESWEGEPWGKEGQPG
                     EWMSLVGLNADDFPPANEPVIAKLKRVYAG"
     misc_feature    113411..113782
                     /gene="mutT"
                     /locus_tag="ECOK1_0100"
                     /note="The MutT pyrophosphohydrolase is a prototypical
                     Nudix hydrolase that catalyzes the hydrolysis of
                     nucleoside and deoxynucleoside triphosphates (NTPs and
                     dNTPs) by substitution at a beta-phosphorus to yield a
                     nucleotide monophosphate (NMP) and inorganic...; Region:
                     MutT_pyrophosphohydrolase; cd03425"
                     /db_xref="CDD:239517"
     misc_feature    order(113411..113413,113417..113419,113513..113518,
                     113522..113524,113558..113560,113567..113572,
                     113639..113641,113693..113695,113756..113758)
                     /gene="mutT"
                     /locus_tag="ECOK1_0100"
                     /note="active site"
                     /db_xref="CDD:239517"
     misc_feature    order(113411..113413,113417..113419,113513..113518,
                     113633..113635,113639..113641,113756..113758)
                     /gene="mutT"
                     /locus_tag="ECOK1_0100"
                     /note="8-oxo-dGMP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239517"
     misc_feature    113513..113581
                     /gene="mutT"
                     /locus_tag="ECOK1_0100"
                     /note="nudix motif; other site"
                     /db_xref="CDD:239517"
     misc_feature    order(113558..113560,113567..113572)
                     /gene="mutT"
                     /locus_tag="ECOK1_0100"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:239517"
     gene            complement(113888..114085)
                     /locus_tag="ECOK1_0101"
                     /db_xref="GeneID:12688669"
     CDS             complement(113888..114085)
                     /locus_tag="ECOK1_0101"
                     /note="identified by similarity to SP:P0A8H8; match to
                     protein family HMM PF03884"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding protein YacG"
                     /protein_id="YP_006099356.1"
                     /db_xref="GI:386597850"
                     /db_xref="GeneID:12688669"
                     /translation="MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIPSSGDLSESDDWSEEPKQ"
     misc_feature    complement(113900..114085)
                     /locus_tag="ECOK1_0101"
                     /note="DNA gyrase inhibitor; Reviewed; Region: PRK00418"
                     /db_xref="CDD:234754"
     gene            complement(114095..114838)
                     /locus_tag="ECOK1_0102"
                     /db_xref="GeneID:12688670"
     CDS             complement(114095..114838)
                     /locus_tag="ECOK1_0102"
                     /note="identified by match to protein family HMM PF07072"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099357.1"
                     /db_xref="GI:386597851"
                     /db_xref="GeneID:12688670"
                     /translation="MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFF
                     RNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVL
                     ISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIAS
                     LNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGH
                     KSRFAIRFMPLDSENGQVPERLDFELACC"
     misc_feature    complement(114098..114829)
                     /locus_tag="ECOK1_0102"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4582"
                     /db_xref="CDD:226948"
     gene            complement(114838..115458)
                     /gene="coaE"
                     /locus_tag="ECOK1_0103"
                     /db_xref="GeneID:12688671"
     CDS             complement(114838..115458)
                     /gene="coaE"
                     /locus_tag="ECOK1_0103"
                     /EC_number="2.7.1.24"
                     /note="identified by match to protein family HMM PF01121;
                     match to protein family HMM TIGR00152"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="YP_006099358.1"
                     /db_xref="GI:386597852"
                     /db_xref="GeneID:12688671"
                     /translation="MRYIVALTGGIGSGKSTVANAFANLGINVIDADIIARQVVEPGA
                     PALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQ
                     ATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
                     TREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP"
     misc_feature    complement(114856..115458)
                     /gene="coaE"
                     /locus_tag="ECOK1_0103"
                     /note="Dephospho-CoA kinase [Coenzyme metabolism]; Region:
                     CoaE; COG0237"
                     /db_xref="CDD:223315"
     misc_feature    complement(114916..115449)
                     /gene="coaE"
                     /locus_tag="ECOK1_0103"
                     /note="Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24)
                     catalyzes the phosphorylation of dephosphocoenzyme A
                     (dCoA) to yield CoA, which is the final step in CoA
                     biosynthesis; Region: DPCK; cd02022"
                     /db_xref="CDD:238980"
     misc_feature    complement(order(114982..114984,115117..115122,
                     115192..115194,115360..115362,115435..115437))
                     /gene="coaE"
                     /locus_tag="ECOK1_0103"
                     /note="CoA-binding site [chemical binding]; other site"
                     /db_xref="CDD:238980"
     misc_feature    complement(order(114934..114936,115039..115041,
                     115414..115419,115426..115434))
                     /gene="coaE"
                     /locus_tag="ECOK1_0103"
                     /note="ATP-binding [chemical binding]; other site"
                     /db_xref="CDD:238980"
     gene            115683..116726
                     /gene="guaC"
                     /locus_tag="ECOK1_0104"
                     /db_xref="GeneID:12688672"
     CDS             115683..116726
                     /gene="guaC"
                     /locus_tag="ECOK1_0104"
                     /EC_number="1.7.1.7"
                     /note="identified by match to protein family HMM PF00478;
                     match to protein family HMM TIGR01305"
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine monophosphate reductase"
                     /protein_id="YP_006099359.1"
                     /db_xref="GI:386597853"
                     /db_xref="GeneID:12688672"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSW
                     SGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVS
                     TGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
                     DGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMK
                     RHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVQEQENRIFNNL"
     misc_feature    115683..116720
                     /gene="guaC"
                     /locus_tag="ECOK1_0104"
                     /note="guanosine 5'-monophosphate oxidoreductase;
                     Provisional; Region: PRK05096"
                     /db_xref="CDD:235343"
     misc_feature    115707..116690
                     /gene="guaC"
                     /locus_tag="ECOK1_0104"
                     /note="IMPDH: The catalytic domain of the inosine
                     monophosphate dehydrogenase. IMPDH catalyzes the
                     NAD-dependent oxidation of inosine 5'-monophosphate (IMP)
                     to xanthosine 5' monophosphate (XMP). It is a
                     rate-limiting step in the de novo synthesis of...; Region:
                     IMPDH; cd00381"
                     /db_xref="CDD:238223"
     misc_feature    order(115836..115838,116232..116240,116337..116339,
                     116343..116345,116406..116411,116478..116480,
                     116484..116492,116547..116552)
                     /gene="guaC"
                     /locus_tag="ECOK1_0104"
                     /note="active site"
                     /db_xref="CDD:238223"
     gene            complement(116761..117963)
                     /gene="pilC"
                     /locus_tag="ECOK1_0105"
                     /db_xref="GeneID:12688673"
     CDS             complement(116761..117963)
                     /gene="pilC"
                     /locus_tag="ECOK1_0105"
                     /note="identified by match to protein family HMM PF00482"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus assembly protein PilC"
                     /protein_id="YP_006099360.1"
                     /db_xref="GI:386597854"
                     /db_xref="GeneID:12688673"
                     /translation="MASKQLWRWHGITGDGNAQDGMLWAESRALLLMALQQQMVTPLS
                     LKRITINSTQWRGDISAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAH
                     DLEQGVAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVK
                     SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLASFSGEWGW
                     LLVLFGFLLAIANKLLMRHPTRLIARQKLLLRIPIMGSLMRGQKLTQIFTILTLTQSA
                     GISFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNAGEFSPLCLQLVRTG
                     EASGSLDLMLDNLAHHHRDNTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     misc_feature    complement(116773..117963)
                     /gene="pilC"
                     /locus_tag="ECOK1_0105"
                     /note="type IV pilin biogenesis protein; Provisional;
                     Region: PRK10573"
                     /db_xref="CDD:182559"
     misc_feature    complement(117406..117774)
                     /gene="pilC"
                     /locus_tag="ECOK1_0105"
                     /note="Type II secretion system (T2SS), protein F; Region:
                     T2SF; pfam00482"
                     /db_xref="CDD:249893"
     misc_feature    complement(116800..117168)
                     /gene="pilC"
                     /locus_tag="ECOK1_0105"
                     /note="Type II secretion system (T2SS), protein F; Region:
                     T2SF; pfam00482"
                     /db_xref="CDD:249893"
     gene            complement(117953..119338)
                     /gene="hofB"
                     /locus_tag="ECOK1_0106"
                     /db_xref="GeneID:12688674"
     CDS             complement(117953..119338)
                     /gene="hofB"
                     /locus_tag="ECOK1_0106"
                     /note="identified by match to protein family HMM PF00437"
                     /codon_start=1
                     /transl_table=11
                     /product="GspE family protein HofB"
                     /protein_id="YP_006099361.1"
                     /db_xref="GI:386597855"
                     /db_xref="GeneID:12688674"
                     /translation="MNIPQLTALCLRYQGVLLDASEEVVHVAVVDAPSHELLDALHFA
                     TTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQPKAELLTRTLQSALEQRASDIHI
                     EPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVEL
                     AGNAVSFRIATLACRGGEKVVLRLLQQVNQALDVNTLGMQPSQLVDFAHALQQPQGLV
                     LVTGPTGSGKTVTLYSALQMLNTADINICSVEDPVEIPIAGLNQTQIHSRAGLTFQGV
                     LRALLRQDPDVIMIGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTCETLVRLQQMGVA
                     RWMLSSALTLVIAQRLVRKLCPHCRRQQGEPIHIPDNVWPSPLPHWQAPGCVHCYHGF
                     YGRTALFEVLPITPVIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEE
                     LIRVLGMPHGE"
     misc_feature    complement(117962..119338)
                     /gene="hofB"
                     /locus_tag="ECOK1_0106"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10436"
                     /db_xref="CDD:236694"
     misc_feature    complement(118154..118933)
                     /gene="hofB"
                     /locus_tag="ECOK1_0106"
                     /note="PulE/GspE The type II secretory pathway is the main
                     terminal branch of the general secretory pathway (GSP).
                     It is responsible for the export the majority of
                     Gram-negative bacterial exoenzymes and toxins. PulE is a
                     cytoplasmic protein of the GSP, which...; Region:
                     PulE-GspE; cd01129"
                     /db_xref="CDD:238549"
     misc_feature    complement(118652..118675)
                     /gene="hofB"
                     /locus_tag="ECOK1_0106"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:238549"
     misc_feature    complement(order(118463..118468,118586..118591,
                     118595..118597,118652..118660,118670..118672))
                     /gene="hofB"
                     /locus_tag="ECOK1_0106"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238549"
     misc_feature    complement(118463..118480)
                     /gene="hofB"
                     /locus_tag="ECOK1_0106"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:238549"
     gene            complement(119348..119788)
                     /gene="pilA"
                     /locus_tag="ECOK1_0107"
                     /db_xref="GeneID:12688675"
     CDS             complement(119348..119788)
                     /gene="pilA"
                     /locus_tag="ECOK1_0107"
                     /note="gene synonym: ppdD; identified by similarity to
                     GB:AAX12396.1; match to protein family HMM PF07963; match
                     to protein family HMM TIGR02532"
                     /codon_start=1
                     /transl_table=11
                     /product="type 4 pilus subunit PilA"
                     /protein_id="YP_006099362.1"
                     /db_xref="GI:386597856"
                     /db_xref="GeneID:12688675"
                     /translation="MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGLNTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNG
                     LSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN"
     misc_feature    complement(119351..119788)
                     /gene="pilA"
                     /locus_tag="ECOK1_0107"
                     /note="putative major pilin subunit; Provisional; Region:
                     PRK10574"
                     /db_xref="CDD:236718"
     misc_feature    complement(119708..119779)
                     /gene="pilA"
                     /locus_tag="ECOK1_0107"
                     /note="prepilin-type N-terminal cleavage/methylation
                     domain; Region: IV_pilin_GFxxxE; TIGR02532"
                     /db_xref="CDD:213719"
     misc_feature    complement(119426..119641)
                     /gene="pilA"
                     /locus_tag="ECOK1_0107"
                     /note="Pilin (bacterial filament); Region: Pilin;
                     pfam00114"
                     /db_xref="CDD:249599"
     gene            complement(119992..120885)
                     /gene="nadC"
                     /locus_tag="ECOK1_0108"
                     /db_xref="GeneID:12688676"
     CDS             complement(119992..120885)
                     /gene="nadC"
                     /locus_tag="ECOK1_0108"
                     /EC_number="2.4.2.19"
                     /note="identified by similarity to SP:P30011; match to
                     protein family HMM PF01729; match to protein family HMM
                     PF02749; match to protein family HMM TIGR00078"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide diphosphorylase"
                     /protein_id="YP_006099363.1"
                     /db_xref="GI:386597857"
                     /db_xref="GeneID:12688676"
                     /translation="MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANND
                     ITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQ
                     PLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
                     SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVEN
                     LEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVD
                     FISVGALTKHVQALDLSMRFR"
     misc_feature    complement(119995..120885)
                     /gene="nadC"
                     /locus_tag="ECOK1_0108"
                     /note="quinolinate phosphoribosyltransferase; Validated;
                     Region: PRK09016"
                     /db_xref="CDD:181612"
     misc_feature    complement(120001..120810)
                     /gene="nadC"
                     /locus_tag="ECOK1_0108"
                     /note="Quinolinate phosphoribosyl transferase (QAPRTase or
                     QPRTase), also called nicotinate-nucleotide
                     pyrophosphorylase, is involved in the de novo synthesis of
                     NAD in both prokaryotes and eukaryotes. It catalyses the
                     reaction of quinolinic acid (QA) with...; Region: QPRTase;
                     cd01572"
                     /db_xref="CDD:238806"
     misc_feature    complement(order(120031..120033,120277..120279,
                     120310..120312,120319..120324,120328..120330,
                     120334..120336,120346..120351,120406..120411,
                     120421..120423,120427..120429,120517..120519,
                     120529..120534,120745..120750))
                     /gene="nadC"
                     /locus_tag="ECOK1_0108"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238806"
     misc_feature    complement(order(120031..120033,120040..120045,
                     120049..120051,120106..120111,120178..120180,
                     120358..120363,120424..120432))
                     /gene="nadC"
                     /locus_tag="ECOK1_0108"
                     /note="active site"
                     /db_xref="CDD:238806"
     gene            120973..121524
                     /gene="ampD"
                     /locus_tag="ECOK1_0109"
                     /db_xref="GeneID:12688677"
     CDS             120973..121524
                     /gene="ampD"
                     /locus_tag="ECOK1_0109"
                     /EC_number="3.5.1.28"
                     /note="identified by similarity to SP:P13016; match to
                     protein family HMM PF01510"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="YP_006099364.1"
                     /db_xref="GI:386597858"
                     /db_xref="GeneID:12688677"
                     /translation="MLLEQGWLAGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDRYPDIANNMTGHCDIAPD
                     RKTDPGPAFDWARFRALVSKETT"
     misc_feature    120979..>121506
                     /gene="ampD"
                     /locus_tag="ECOK1_0109"
                     /note="N-acetyl-anhydromuramyl-L-alanine amidase [Cell
                     envelope biogenesis, outer membrane]; Region: ampD;
                     COG3023"
                     /db_xref="CDD:225567"
     misc_feature    121054..121476
                     /gene="ampD"
                     /locus_tag="ECOK1_0109"
                     /note="Peptidoglycan recognition proteins (PGRPs) are
                     pattern recognition receptors that bind, and in certain
                     cases, hydrolyze peptidoglycans (PGNs) of bacterial cell
                     walls. PGRPs have been divided into three classes: short
                     PGRPs (PGRP-S), that are small (20...; Region: PGRP;
                     cd06583"
                     /db_xref="CDD:133475"
     misc_feature    order(121072..121074,121192..121194,121432..121434,
                     121456..121458,121462..121464)
                     /gene="ampD"
                     /locus_tag="ECOK1_0109"
                     /note="amidase catalytic site [active]"
                     /db_xref="CDD:133475"
     misc_feature    order(121072..121074,121432..121434,121462..121464)
                     /gene="ampD"
                     /locus_tag="ECOK1_0109"
                     /note="Zn binding residues [ion binding]; other site"
                     /db_xref="CDD:133475"
     misc_feature    order(121075..121080,121150..121152,121192..121194,
                     121234..121236,121255..121260,121297..121299,
                     121432..121434,121444..121446,121456..121464)
                     /gene="ampD"
                     /locus_tag="ECOK1_0109"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:133475"
     gene            121521..122375
                     /gene="ampE"
                     /locus_tag="ECOK1_0110"
                     /db_xref="GeneID:12688678"
     CDS             121521..122375
                     /gene="ampE"
                     /locus_tag="ECOK1_0110"
                     /note="identified by similarity to SP:P0AE15"
                     /codon_start=1
                     /transl_table=11
                     /product="protein AmpE"
                     /protein_id="YP_006099365.1"
                     /db_xref="GI:386597859"
                     /db_xref="GeneID:12688678"
                     /translation="MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTL
                     CMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRND
                     SHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
                     TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKAL
                     PAWFASLGDFHTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIAL
                     LTIYGALV"
     misc_feature    121521..122372
                     /gene="ampE"
                     /locus_tag="ECOK1_0110"
                     /note="regulatory protein AmpE; Provisional; Region:
                     PRK10987"
                     /db_xref="CDD:236811"
     gene            complement(122418..123788)
                     /gene="aroP"
                     /locus_tag="ECOK1_0111"
                     /db_xref="GeneID:12688679"
     CDS             complement(122418..123788)
                     /gene="aroP"
                     /locus_tag="ECOK1_0111"
                     /note="identified by similarity to SP:P15993; match to
                     protein family HMM PF00324"
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transport protein AroP"
                     /protein_id="YP_006099366.1"
                     /db_xref="GI:386597860"
                     /db_xref="GeneID:12688679"
                     /translation="MEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAG
                     PGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVLY
                     VLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKV
                     IAVVAMIIFGAWLLFSGNGGPQASVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLEL
                     VGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFH
                     ELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPVN
                     TILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQGV
                     VTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKTA
                     KAVKAH"
     misc_feature    complement(122421..123788)
                     /gene="aroP"
                     /locus_tag="ECOK1_0111"
                     /note="aromatic amino acid transporter; Provisional;
                     Region: PRK10238"
                     /db_xref="CDD:182324"
     misc_feature    complement(122454..123671)
                     /gene="aroP"
                     /locus_tag="ECOK1_0111"
                     /note="Transmembrane amino acid transporter protein;
                     Region: Aa_trans; cl17468"
                     /db_xref="CDD:266708"
     gene            124316..126097
                     /locus_tag="ECOK1_0112"
                     /db_xref="GeneID:12688680"
     CDS             124316..126097
                     /locus_tag="ECOK1_0112"
                     /note="identified by match to protein family HMM PF01844;
                     match to protein family HMM PF05638; match to protein
                     family HMM PF06958; match to protein family HMM TIGR03344"
                     /codon_start=1
                     /transl_table=11
                     /product="S-type pyocin family protein"
                     /protein_id="YP_006099367.1"
                     /db_xref="GI:386597861"
                     /db_xref="GeneID:12688680"
                     /translation="MGDIVYLRIIGEKQGDISSGCGTYASVGNRWQVGHEDEIFAFAL
                     TNAITSTGKGVNLQGLQFCKLIDKSSPLLSNAINQNERLFIEIDLYRINKSGRWERYY
                     YIQLRNASLTAIHVNISDNNLPTECVNVNYDYILCKHLIANTEFDWLAFPAGYNSLFI
                     PPKNPPASNLNPEPLPVVNLPLSPPAVKPVYAKSCLKEKGCTDAGTAEEPAENFGQVA
                     IFALPVVDDCCGYHHPEANDVGQPAEAQTMLLFPGSVLAAQIWGKWSLSGILSATCGS
                     YIGALASALYIPSAGEGSARVPGRDEFWYEEELRQKALAGSTATTRVRFFWGTDIHGK
                     PQVYGVHTGEGTPYENVRVANMQWNEQTQRYEFTPAHDVDGPLITWTPENPEHGYVPG
                     HTGNDRPPLEQPTILVTPIPDGTDTYTTPPFPVPDPKEFNDYILVFPAGSGIKPIYVY
                     LKEDPRKLPGVVTGRGVPLSPGTRWLDMSVSNNGNGAPIPAHIADKLRGREFKTFDEF
                     REALWLEVSQDPELIAQFSSGNQTRIKQGLTAKAPIDGWYYGPKEIVKKFQIHHRVAV
                     EYGGSVYDIDNLRIVTPRLHDEIHYRR"
     misc_feature    124325..124759
                     /locus_tag="ECOK1_0112"
                     /note="Protein of unknown function (DUF796); Region:
                     DUF796; cl01226"
                     /db_xref="CDD:260845"
     misc_feature    125240..125665
                     /locus_tag="ECOK1_0112"
                     /note="S-type Pyocin; Region: Pyocin_S; pfam06958"
                     /db_xref="CDD:253990"
     misc_feature    125675..126088
                     /locus_tag="ECOK1_0112"
                     /note="DNase/tRNase domain of colicin-like bacteriocin;
                     Region: Colicin-DNase; pfam12639"
                     /db_xref="CDD:257184"
     misc_feature    <125951..126085
                     /locus_tag="ECOK1_0112"
                     /note="HNH nucleases; HNH endonuclease signature which is
                     found in viral, prokaryotic, and eukaryotic proteins. The
                     alignment includes members of the large group of homing
                     endonucleases, yeast intron 1 protein, MutS, as well as
                     bacterial colicins, pyocins, and...; Region: HNHc;
                     cd00085"
                     /db_xref="CDD:238038"
     misc_feature    order(125990..125992,125996..126004,126008..126010,
                     126044..126049,126059..126064,126071..126073,
                     126083..126085)
                     /locus_tag="ECOK1_0112"
                     /note="active site"
                     /db_xref="CDD:238038"
     gene            126792..127082
                     /locus_tag="ECOK1_0113"
                     /db_xref="GeneID:12688681"
     CDS             126792..127082
                     /locus_tag="ECOK1_0113"
                     /note="identified by similarity to SP:P09881; match to
                     protein family HMM PF01320"
                     /codon_start=1
                     /transl_table=11
                     /product="colicin immunity protein"
                     /protein_id="YP_006099368.1"
                     /db_xref="GI:386597862"
                     /db_xref="GeneID:12688681"
                     /translation="MYNFKDEIEDYTEREFIELLGEFTNPTGDNAQLKGEELDKYWDD
                     LEEHLTRITQHPLMSDLIYYPAKKGDDEPENILKIVKEWRRSQGLPLFKDSK"
     misc_feature    126795..127073
                     /locus_tag="ECOK1_0113"
                     /note="Colicin immunity protein / pyocin immunity protein;
                     Region: Colicin_Pyocin; pfam01320"
                     /db_xref="CDD:250530"
     gene            127491..127781
                     /locus_tag="ECOK1_0114"
                     /db_xref="GeneID:12688682"
     CDS             127491..127781
                     /locus_tag="ECOK1_0114"
                     /note="identified by similarity to SP:P09881; match to
                     protein family HMM PF01320"
                     /codon_start=1
                     /transl_table=11
                     /product="colicin immunity protein"
                     /protein_id="YP_006099369.1"
                     /db_xref="GI:386597863"
                     /db_xref="GeneID:12688682"
                     /translation="MHDLKYKIYFYTEGEFLEMLEEIVNATSKDKSLKGKKLEKYLDT
                     LVDHFIKITEHPKKGDLIFYPNSPEDGKPENILKIVKEWRRSQGLPLFKDSE"
     misc_feature    127497..127772
                     /locus_tag="ECOK1_0114"
                     /note="Colicin immunity protein / pyocin immunity protein;
                     Region: Colicin_Pyocin; pfam01320"
                     /db_xref="CDD:250530"
     gene            128237..129001
                     /locus_tag="ECOK1_0115"
                     /db_xref="GeneID:12688683"
     CDS             128237..129001
                     /locus_tag="ECOK1_0115"
                     /note="identified by match to protein family HMM PF00392;
                     match to protein family HMM PF07729"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_006099370.1"
                     /db_xref="GI:386597864"
                     /db_xref="GeneID:12688683"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLE
                     TRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN"
     misc_feature    128237..128938
                     /locus_tag="ECOK1_0115"
                     /note="transcriptional regulator PdhR; Reviewed; Region:
                     pdhR; PRK09464"
                     /db_xref="CDD:181879"
     misc_feature    128264..128458
                     /locus_tag="ECOK1_0115"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    order(128264..128266,128270..128272,128339..128341,
                     128345..128350,128372..128386,128390..128395,
                     128402..128404,128432..128437,128441..128452)
                     /locus_tag="ECOK1_0115"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    128531..128914
                     /locus_tag="ECOK1_0115"
                     /note="This entry represents the C-terminal ligand binding
                     domain of many members of the GntR family; Region: FCD;
                     smart00895"
                     /db_xref="CDD:214892"
     gene            129162..131825
                     /gene="aceE"
                     /locus_tag="ECOK1_0116"
                     /db_xref="GeneID:12688684"
     CDS             129162..131825
                     /gene="aceE"
                     /locus_tag="ECOK1_0116"
                     /EC_number="1.2.4.1"
                     /note="identified by match to protein family HMM
                     TIGR00759"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="YP_006099371.1"
                     /db_xref="GI:386597865"
                     /db_xref="GeneID:12688684"
                     /translation="MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEA
                     RKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
                     EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKII
                     NELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTI
                     KGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHT
                     YLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETLEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAIAKFNIDADKVNPRLA"
     misc_feature    129162..131822
                     /gene="aceE"
                     /locus_tag="ECOK1_0116"
                     /note="pyruvate dehydrogenase subunit E1; Reviewed;
                     Region: aceE; PRK09405"
                     /db_xref="CDD:236500"
     misc_feature    129387..130544
                     /gene="aceE"
                     /locus_tag="ECOK1_0116"
                     /note="Thiamine pyrophosphate (TPP) family, E1 of E. coli
                     PDC-like subfamily, TPP-binding module; composed of
                     proteins similar to the E1 component of the Escherichia
                     coli pyruvate dehydrogenase multienzyme complex (PDC). PDC
                     catalyzes the oxidative...; Region: TPP_E1_EcPDC_like;
                     cd02017"
                     /db_xref="CDD:238975"
     misc_feature    order(129465..129473,129660..129671,129690..129695,
                     129699..129701,129705..129707,129732..129734,
                     129738..129746,129864..129875,129882..129884,
                     129891..129893,129903..129905,129951..129959,
                     129969..129971,129993..129995,130002..130007,
                     130014..130016)
                     /gene="aceE"
                     /locus_tag="ECOK1_0116"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238975"
     misc_feature    order(129489..129491,129582..129584,129588..129590,
                     129738..129740,129744..129746,129852..129860,
                     129867..129869,129942..129944,129948..129950,
                     130338..130340)
                     /gene="aceE"
                     /locus_tag="ECOK1_0116"
                     /note="TPP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238975"
     gene            131840..133732
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /db_xref="GeneID:12688685"
     CDS             131840..133732
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /EC_number="2.3.1.12"
                     /note="identified by similarity to SP:P06959; match to
                     protein family HMM PF00198; match to protein family HMM
                     PF00364; match to protein family HMM PF02817; match to
                     protein family HMM TIGR01348"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="YP_006099372.1"
                     /db_xref="GI:386597866"
                     /db_xref="GeneID:12688685"
                     /translation="MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAA
                     AAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNVGDKVSTGSLIMVFEVAGEAGAVAPAAKQEAAPAAAPASAAGVKEVNVPDIGGDE
                     VEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIM
                     IFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIR
                     RLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKV
                     DFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAK
                     RKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVV
                     PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVN
                     APEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSD
                     IRRLVM"
     misc_feature    131840..133729
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /note="pyruvate dehydrogenase dihydrolipoyltransacetylase;
                     Validated; Region: aceF; PRK11854"
                     /db_xref="CDD:236999"
     misc_feature    131846..132061
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /note="Lipoyl domain of the dihydrolipoyl acyltransferase
                     component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid
                     dehydrogenase multienzyme complexes, like pyruvate
                     dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH)
                     and branched-chain 2-oxo acid...; Region: lipoyl_domain;
                     cd06849"
                     /db_xref="CDD:133458"
     misc_feature    order(131930..131932,131951..131968,131978..131980)
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /note="E3 interaction surface; other site"
                     /db_xref="CDD:133458"
     misc_feature    131960..131962
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /note="lipoyl attachment site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133458"
     misc_feature    132158..132370
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /note="Lipoyl domain of the dihydrolipoyl acyltransferase
                     component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid
                     dehydrogenase multienzyme complexes, like pyruvate
                     dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH)
                     and branched-chain 2-oxo acid...; Region: lipoyl_domain;
                     cd06849"
                     /db_xref="CDD:133458"
     misc_feature    order(132239..132241,132260..132277,132287..132289)
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /note="E3 interaction surface; other site"
                     /db_xref="CDD:133458"
     misc_feature    132269..132271
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /note="lipoyl attachment site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133458"
     misc_feature    132458..132673
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /note="Lipoyl domain of the dihydrolipoyl acyltransferase
                     component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid
                     dehydrogenase multienzyme complexes, like pyruvate
                     dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH)
                     and branched-chain 2-oxo acid...; Region: lipoyl_domain;
                     cd06849"
                     /db_xref="CDD:133458"
     misc_feature    order(132542..132544,132563..132580,132590..132592)
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /note="E3 interaction surface; other site"
                     /db_xref="CDD:133458"
     misc_feature    132572..132574
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /note="lipoyl attachment site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133458"
     misc_feature    132818..132928
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /note="e3 binding domain; Region: E3_binding; pfam02817"
                     /db_xref="CDD:251550"
     misc_feature    133085..133729
                     /gene="aceF"
                     /locus_tag="ECOK1_0117"
                     /note="2-oxoacid dehydrogenases acyltransferase (catalytic
                     domain); Region: 2-oxoacid_dh; pfam00198"
                     /db_xref="CDD:249671"
     gene            133940..135364
                     /gene="lpdA"
                     /locus_tag="ECOK1_0118"
                     /db_xref="GeneID:12688686"
     CDS             133940..135364
                     /gene="lpdA"
                     /locus_tag="ECOK1_0118"
                     /EC_number="1.8.1.4"
                     /note="identified by match to protein family HMM PF00070;
                     match to protein family HMM PF01134; match to protein
                     family HMM PF02852; match to protein family HMM PF07992;
                     match to protein family HMM TIGR01350"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="YP_006099373.1"
                     /db_xref="GI:386597867"
                     /db_xref="GeneID:12688686"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEVFEGSITDLPNPKAKKK"
     misc_feature    133946..135355
                     /gene="lpdA"
                     /locus_tag="ECOK1_0118"
                     /note="dihydrolipoamide dehydrogenase; Reviewed; Region:
                     PRK06467"
                     /db_xref="CDD:180579"
     misc_feature    133964..>134068
                     /gene="lpdA"
                     /locus_tag="ECOK1_0118"
                     /note="Short-chain dehydrogenases/reductases (SDR);
                     Region: SDR; cl21454"
                     /db_xref="CDD:271874"
     misc_feature    134468..134704
                     /gene="lpdA"
                     /locus_tag="ECOK1_0118"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:249559"
     misc_feature    134978..135307
                     /gene="lpdA"
                     /locus_tag="ECOK1_0118"
                     /note="Pyridine nucleotide-disulphide oxidoreductase,
                     dimerization domain; Region: Pyr_redox_dim; pfam02852"
                     /db_xref="CDD:251571"
     gene            complement(135606..137363)
                     /locus_tag="ECOK1_0119"
                     /db_xref="GeneID:12688687"
     CDS             complement(135606..137363)
                     /locus_tag="ECOK1_0119"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099374.1"
                     /db_xref="GI:386597868"
                     /db_xref="GeneID:12688687"
                     /translation="MKMTLPFKPHVLALICSAGLCAASAGLYIKSRTVEAPVEAQSTQ
                     QTAPDISAVTLPATVSAPPVTPAVVKSAFSTAQIDQWVAPVALYPDSLLSQVLMASTY
                     PANVAQAVQWSHDNPLKQGDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNL
                     GDAFLAQPQDVMDSVQRLRQLAQQTGSLKSSTEQKIIATTKKVVPVNQPANAPATQSN
                     TVSTSSPVVAEPAPTVITIEPANPDVVYIPNYNPNVVYGSWANTAYPPVYLPPPAGEP
                     FVDSFVRGFGYSMGVATTYALFSSIDWDDDDHDHHHHDDDDYHHHDGGHRDGNDWQHN
                     GDNINIDVNNFNRITGEHLTDKNMAWRHNPNYRNGVTYHDQDMAKRFHQTDVNGGMSA
                     TQLPAPTRDSQRHAAASQFQQRTHAAPVITRDTQRQAAAQRFNEAEHYGSYDDFRDFS
                     RRQPLTQQQKDAARQRYQSASPEQRQAVREKIQANPQNQQRREAARQRIQSASPEQRQ
                     AVREKMQTNPQNQQQRDAARQRIQSASPEQRQVFREKVQESRPQRLNDSNHTARLNNE
                     QRSAVRERLSERGARRLER"
     misc_feature    complement(136275..137147)
                     /locus_tag="ECOK1_0119"
                     /note="Protein of unknown function (DUF3300); Region:
                     DUF3300; pfam11737"
                     /db_xref="CDD:256584"
     misc_feature    complement(135729..136001)
                     /locus_tag="ECOK1_0119"
                     /note="Protein of unknown function (DUF3106); Region:
                     DUF3106; pfam11304"
                     /db_xref="CDD:256404"
     gene            137718..140315
                     /gene="acnB"
                     /locus_tag="ECOK1_0120"
                     /db_xref="GeneID:12688688"
     CDS             137718..140315
                     /gene="acnB"
                     /locus_tag="ECOK1_0120"
                     /EC_number="4.2.1.3"
                     /note="identified by match to protein family HMM PF00330;
                     match to protein family HMM PF06434; match to protein
                     family HMM TIGR00117"
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase 2"
                     /protein_id="YP_006099375.1"
                     /db_xref="GI:386597869"
                     /db_xref="GeneID:12688688"
                     /translation="MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEF
                     LLDLLTNRVPPGVDEAAYVKAGFLAAVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRP
                     ALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVG
                     PIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
                     TGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFDQLSQYTEKA
                     DGVIFQTAV"
     misc_feature    137718..140255
                     /gene="acnB"
                     /locus_tag="ECOK1_0120"
                     /note="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase; Validated; Region:
                     PRK09238"
                     /db_xref="CDD:236424"
     misc_feature    137727..138185
                     /gene="acnB"
                     /locus_tag="ECOK1_0120"
                     /note="Aconitate B N-terminal domain; Region:
                     Aconitase_B_N; pfam11791"
                     /db_xref="CDD:256624"
     misc_feature    138228..138650
                     /gene="acnB"
                     /locus_tag="ECOK1_0120"
                     /note="Aconitase B swivel domain. Aconitate hydratase B is
                     involved in energy metabolism as part of the TCA cycle. It
                     catalyses the formation of cis-aconitate from citrate.
                     This is the aconitase swivel domain, which undergoes
                     swivelling conformational change in...; Region:
                     AcnB_Swivel; cd01576"
                     /db_xref="CDD:238808"
     misc_feature    138447..138455
                     /gene="acnB"
                     /locus_tag="ECOK1_0120"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238808"
     misc_feature    138867..140177
                     /gene="acnB"
                     /locus_tag="ECOK1_0120"
                     /note="Aconitate hydratase B catalyses the formation of
                     cis-aconitate from citrate as part of the TCA cycle;
                     Region: AcnB; cd01581"
                     /db_xref="CDD:153131"
     misc_feature    order(138957..138959,138966..138968,139206..139211,
                     140034..140036,140088..140090,140103..140105)
                     /gene="acnB"
                     /locus_tag="ECOK1_0120"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:153131"
     misc_feature    order(139212..139214,139845..139847,140022..140024,
                     140031..140036,140085..140087)
                     /gene="acnB"
                     /locus_tag="ECOK1_0120"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:153131"
     gene            140490..140852
                     /locus_tag="ECOK1_0121"
                     /db_xref="GeneID:12688689"
     CDS             140490..140852
                     /locus_tag="ECOK1_0121"
                     /note="identified by similarity to SP:P59396; match to
                     protein family HMM PF06062"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099376.1"
                     /db_xref="GI:386597870"
                     /db_xref="GeneID:12688689"
                     /translation="MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQ
                     AAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCG
                     VEDFLQVVAAYRNFVQQK"
     misc_feature    140490..140849
                     /locus_tag="ECOK1_0121"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3112"
                     /db_xref="CDD:225654"
     gene            complement(140890..141684)
                     /gene="speD"
                     /locus_tag="ECOK1_0122"
                     /db_xref="GeneID:12688690"
     CDS             complement(140890..141684)
                     /gene="speD"
                     /locus_tag="ECOK1_0122"
                     /EC_number="4.1.1.50"
                     /note="identified by match to protein family HMM PF02675;
                     match to protein family HMM TIGR03331"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine decarboxylase"
                     /protein_id="YP_006099377.1"
                     /db_xref="GI:386597871"
                     /db_xref="GeneID:12688690"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTTEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSEDMKALYDMVDVNVYQENIFHTKML
                     LKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV"
     misc_feature    complement(140893..141684)
                     /gene="speD"
                     /locus_tag="ECOK1_0122"
                     /note="S-adenosylmethionine decarboxylase; Provisional;
                     Region: PRK05462"
                     /db_xref="CDD:235480"
     gene            complement(141700..142566)
                     /gene="speE"
                     /locus_tag="ECOK1_0123"
                     /db_xref="GeneID:12688691"
     CDS             complement(141700..142566)
                     /gene="speE"
                     /locus_tag="ECOK1_0123"
                     /EC_number="2.5.1.16"
                     /note="identified by match to protein family HMM PF01564;
                     match to protein family HMM TIGR00417"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine synthase"
                     /protein_id="YP_006099378.1"
                     /db_xref="GI:386597872"
                     /db_xref="GeneID:12688691"
                     /translation="MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     SITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTNQTFDVIISDCT
                     DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAVHTAAFALP
                     QYLQDALASQPS"
     misc_feature    complement(141994..142326)
                     /gene="speE"
                     /locus_tag="ECOK1_0123"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(142093..142095,142144..142152,
                     142240..142245,142297..142317))
                     /gene="speE"
                     /locus_tag="ECOK1_0123"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(142672..143019)
                     /locus_tag="ECOK1_0124"
                     /db_xref="GeneID:12688692"
     CDS             complement(142672..143019)
                     /locus_tag="ECOK1_0124"
                     /note="identified by similarity to GB:AAV76203.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099379.1"
                     /db_xref="GI:386597873"
                     /db_xref="GeneID:12688692"
                     /translation="MKTFFRTVLFGSLMAVCANSYALSESEAEDMADLTAVFVFLKND
                     CGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKA
                     LARDSLSLLAYVK"
     misc_feature    complement(142705..>142935)
                     /locus_tag="ECOK1_0124"
                     /note="Bacterial chaperone lipoprotein (PulS_OutS);
                     Region: PulS_OutS; pfam09691"
                     /db_xref="CDD:255487"
     gene            143146..144735
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /db_xref="GeneID:12688693"
     CDS             143146..144735
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="identified by similarity to SP:P36649; match to
                     protein family HMM PF07731; match to protein family HMM
                     PF07732; match to protein family HMM TIGR01409"
                     /codon_start=1
                     /transl_table=11
                     /product="copper oxidase CueO"
                     /protein_id="YP_006099380.1"
                     /db_xref="GI:386597874"
                     /db_xref="GeneID:12688693"
                     /translation="MILFRLLKNKEITMQRRDFLKYSVALGVASALPLWSRAVFAAER
                     PTLPIPDLLTTDARNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKLQRGKAVTVD
                     IYNQLTEETTLHWHGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGK
                     TGRQVAMGLAGLVVIEDDEILKLMLPKQWGIDDVPVIVQDKKFNADGQIDYQLDVMTA
                     AVGWFGDTLLTNGAIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGL
                     LPEPVKVSELPVLMGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQP
                     IAISASGALPDTLSSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGM
                     DHSQMMGHMGHGNMNHMNHSGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGV
                     GDMMLHPFHIHGTQFRILSENGKPPATHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHA
                     YMAHCHLLEHEDTGMMLGFTV"
     misc_feature    143185..144732
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="multicopper oxidase; Provisional; Region: PRK10965"
                     /db_xref="CDD:236810"
     misc_feature    143323..143676
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="The first Cupredoxin domain of the multicopper
                     oxidase CueO, the cell division protein FtsP, and similar
                     proteins; Region: CuRO_1_CueO_FtsP; cd04232"
                     /db_xref="CDD:259894"
     misc_feature    order(143368..143382,143401..143406,143413..143415,
                     143491..143496,143587..143601,143629..143634,
                     143638..143646,143659..143661,143665..143667)
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="Domain 2 interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:259894"
     misc_feature    order(143485..143487,143491..143496,143500..143514,
                     143518..143520,143527..143532,143599..143601,
                     143605..143607,143611..143613,143617..143631,
                     143638..143640)
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="Domain 3 interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:259894"
     misc_feature    order(143485..143487,143491..143493,143605..143607,
                     143611..143613)
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="trinuclear Cu binding site [ion binding]; other
                     site"
                     /db_xref="CDD:259894"
     misc_feature    143719..144147
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="The second Cupredoxin domain of the multicopper
                     oxidase CueO, the cell division protein FtsP, and similar
                     proteins; Region: CuRO_2_CueO_FtsP; cd13867"
                     /db_xref="CDD:259935"
     misc_feature    order(143725..143736,143746..143748,143821..143823,
                     143830..143841,143851..143853,143878..143880,
                     143884..143886,143890..143892,143962..143970,
                     144016..144018,144022..144024,144127..144129,
                     144133..144138)
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="Domain 1 interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:259935"
     misc_feature    order(143905..143907,143911..143913,143950..143955,
                     143959..143973,143980..143988,143992..143994,
                     144004..144006,144010..144027)
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="Domain 3 interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:259935"
     misc_feature    144400..144732
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="The third Cupredoxin domain of the multicopper
                     oxidase CueO, the cell division protein FtsP, and similar
                     proteins; Region: CuRO_3_CueO_FtsP; cd13890"
                     /db_xref="CDD:259957"
     misc_feature    order(144406..144408,144505..144510,144514..144516,
                     144535..144537,144577..144582,144589..144600,
                     144604..144606,144685..144699,144706..144708)
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="Domain 2 interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:259957"
     misc_feature    order(144427..144429,144433..144435,144520..144522,
                     144526..144528,144532..144537,144595..144597,
                     144646..144648,144664..144675,144679..144681,
                     144685..144687,144691..144696,144700..144705,
                     144715..144717)
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="Domain 1 interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:259957"
     misc_feature    order(144511..144513,144682..144684,144697..144699,
                     144712..144714)
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="Type 1 (T1) Cu binding site [ion binding]; other
                     site"
                     /db_xref="CDD:259957"
     misc_feature    order(144520..144522,144526..144528,144679..144681,
                     144685..144687)
                     /gene="cueO"
                     /locus_tag="ECOK1_0125"
                     /note="trinuclear Cu binding site [ion binding]; other
                     site"
                     /db_xref="CDD:259957"
     gene            complement(144782..147172)
                     /gene="gcd"
                     /locus_tag="ECOK1_0126"
                     /db_xref="GeneID:12688694"
     CDS             complement(144782..147172)
                     /gene="gcd"
                     /locus_tag="ECOK1_0126"
                     /EC_number="1.1.5.2"
                     /note="identified by similarity to SP:P15877; match to
                     protein family HMM PF01011; match to protein family HMM
                     TIGR03074"
                     /codon_start=1
                     /transl_table=11
                     /product="quinoprotein glucose dehydrogenase"
                     /protein_id="YP_006099381.1"
                     /db_xref="GI:386597875"
                     /db_xref="GeneID:12688694"
                     /translation="MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYP
                     IAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGI
                     WLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEISGTLSADTTPAEAI
                     SPVADQDWPAYGRNQEGQRFSPLKQINTDNVHKLKEAWVFRTGDVKQPNDPGEITNEV
                     TPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAE
                     TASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYE
                     PTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSD
                     EHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
                     GKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELV
                     VPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRVMFHQM
                     RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGN
                     PMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEV
                     VWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
                     GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK"
     misc_feature    complement(144797..147076)
                     /gene="gcd"
                     /locus_tag="ECOK1_0126"
                     /note="membrane-bound PQQ-dependent dehydrogenase,
                     glucose/quinate/shikimate family; Region: PQQ_membr_DH;
                     TIGR03074"
                     /db_xref="CDD:234101"
     misc_feature    complement(144800..146671)
                     /gene="gcd"
                     /locus_tag="ECOK1_0126"
                     /note="Membrane-bound PQQ-dependent glucose dehydrogenase;
                     Region: PQQ_mGDH; cd10280"
                     /db_xref="CDD:199838"
     misc_feature    complement(order(144803..144805,144809..144811,
                     144938..144940,144947..144955,144962..144964,
                     144968..144970,145121..145123,145130..145138,
                     145145..145147,145151..145153,145646..145648,
                     145655..145663,145670..145672,145676..145678,
                     145808..145810,145817..145825,145832..145834,
                     145838..145840,146042..146044,146051..146059,
                     146066..146068,146072..146074,146240..146242,
                     146249..146257,146264..146266,146270..146272,
                     146429..146431,146438..146446,146453..146455,
                     146459..146461,146579..146581,146588..146596))
                     /gene="gcd"
                     /locus_tag="ECOK1_0126"
                     /note="Trp docking motif [polypeptide binding]; other
                     site"
                     /db_xref="CDD:199838"
     misc_feature    complement(order(145037..145039,145694..145696,
                     145961..145963,146117..146122,146165..146167,
                     146375..146377,146390..146395,146522..146524))
                     /gene="gcd"
                     /locus_tag="ECOK1_0126"
                     /note="putative active site [active]"
                     /db_xref="CDD:199838"
     gene            147378..147914
                     /gene="hpt"
                     /locus_tag="ECOK1_0127"
                     /db_xref="GeneID:12688695"
     CDS             147378..147914
                     /gene="hpt"
                     /locus_tag="ECOK1_0127"
                     /EC_number="2.4.2.8"
                     /note="identified by similarity to SP:P0A9M2; match to
                     protein family HMM PF00156; match to protein family HMM
                     TIGR01203"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="YP_006099382.1"
                     /db_xref="GI:386597876"
                     /db_xref="GeneID:12688695"
                     /translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRG
                     SFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
                     DSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
                     AQRYRHLPYIGKVILLDE"
     misc_feature    147429..147785
                     /gene="hpt"
                     /locus_tag="ECOK1_0127"
                     /note="Phosphoribosyl transferase (PRT)-type I domain;
                     Region: PRTases_typeI; cd06223"
                     /db_xref="CDD:206754"
     misc_feature    order(147501..147503,147507..147509,147672..147680,
                     147684..147698,147768..147770)
                     /gene="hpt"
                     /locus_tag="ECOK1_0127"
                     /note="active site"
                     /db_xref="CDD:206754"
     gene            complement(147955..148617)
                     /gene="can"
                     /locus_tag="ECOK1_0128"
                     /db_xref="GeneID:12688696"
     CDS             complement(147955..148617)
                     /gene="can"
                     /locus_tag="ECOK1_0128"
                     /note="identified by match to protein family HMM PF00484"
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="YP_006099383.1"
                     /db_xref="GI:386597877"
                     /db_xref="GeneID:12688696"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCG
                     GVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH
                     STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHIN
                     HK"
     misc_feature    complement(148045..148587)
                     /gene="can"
                     /locus_tag="ECOK1_0128"
                     /note="Carbonic anhydrases (CA) are zinc-containing
                     enzymes that catalyze the reversible hydration of carbon
                     dioxide in a two-step mechanism in which the nucleophilic
                     attack of a zinc-bound hydroxide ion on carbon dioxide is
                     followed by the regeneration of an...; Region:
                     beta_CA_cladeA; cd00883"
                     /db_xref="CDD:238448"
     misc_feature    complement(order(148075..148077,148315..148317,
                     148324..148326,148354..148356,148369..148371,
                     148435..148437,148444..148446,148480..148488,
                     148492..148494,148513..148515,148519..148521))
                     /gene="can"
                     /locus_tag="ECOK1_0128"
                     /note="active site clefts [active]"
                     /db_xref="CDD:238448"
     misc_feature    complement(order(148315..148317,148324..148326,
                     148486..148488,148492..148494))
                     /gene="can"
                     /locus_tag="ECOK1_0128"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:238448"
     misc_feature    complement(order(148054..148056,148060..148062,
                     148066..148071,148075..148077,148261..148263,
                     148369..148374,148381..148386,148426..148428,
                     148432..148434,148438..148446,148459..148461,
                     148465..148470,148474..148476,148480..148491))
                     /gene="can"
                     /locus_tag="ECOK1_0128"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238448"
     gene            148726..149652
                     /locus_tag="ECOK1_0129"
                     /db_xref="GeneID:12688697"
     CDS             148726..149652
                     /locus_tag="ECOK1_0129"
                     /note="identified by match to protein family HMM PF00005"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="YP_006099384.1"
                     /db_xref="GI:386597878"
                     /db_xref="GeneID:12688697"
                     /translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
                     STTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLS
                     EQGIQVLSMRNKANRLEELFVSLVNEKQGDRT"
     misc_feature    148726..149631
                     /locus_tag="ECOK1_0129"
                     /note="ABC-type multidrug transport system, ATPase
                     component [Defense mechanisms]; Region: CcmA; COG1131"
                     /db_xref="CDD:224054"
     misc_feature    148738..149367
                     /locus_tag="ECOK1_0129"
                     /note="ATP-binding cassette domain of the drug resistance
                     transporter and related proteins, subfamily A; Region:
                     ABC_DR_subfamily_A; cd03230"
                     /db_xref="CDD:213197"
     misc_feature    148837..148860
                     /locus_tag="ECOK1_0129"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213197"
     misc_feature    order(148846..148851,148855..148863,148978..148980,
                     149206..149211,149305..149307)
                     /locus_tag="ECOK1_0129"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213197"
     misc_feature    148969..148980
                     /locus_tag="ECOK1_0129"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213197"
     misc_feature    149134..149163
                     /locus_tag="ECOK1_0129"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213197"
     misc_feature    149194..149211
                     /locus_tag="ECOK1_0129"
                     /note="Walker B; other site"
                     /db_xref="CDD:213197"
     misc_feature    149218..149229
                     /locus_tag="ECOK1_0129"
                     /note="D-loop; other site"
                     /db_xref="CDD:213197"
     misc_feature    149293..149313
                     /locus_tag="ECOK1_0129"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213197"
     gene            149649..150419
                     /locus_tag="ECOK1_0130"
                     /db_xref="GeneID:12688698"
     CDS             149649..150419
                     /locus_tag="ECOK1_0130"
                     /note="identified by match to protein family HMM PF01061"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="YP_006099385.1"
                     /db_xref="GI:386597879"
                     /db_xref="GeneID:12688698"
                     /translation="MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPT
                     HVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
                     GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS"
     misc_feature    149649..150416
                     /locus_tag="ECOK1_0130"
                     /note="inner membrane transport permease; Provisional;
                     Region: PRK15066"
                     /db_xref="CDD:237896"
     misc_feature    149649..150413
                     /locus_tag="ECOK1_0130"
                     /note="ABC-type multidrug transport system, permease
                     component [Defense mechanisms]; Region: COG0842"
                     /db_xref="CDD:223912"
     gene            150524..150964
                     /locus_tag="ECOK1_0131"
                     /db_xref="GeneID:12688699"
     CDS             150524..150964
                     /locus_tag="ECOK1_0131"
                     /note="identified by match to protein family HMM PF03610"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIA"
                     /protein_id="YP_006099386.1"
                     /db_xref="GI:386597880"
                     /db_xref="GeneID:12688699"
                     /translation="MLGWVITCHDDRAQEILDALEKKHGALLQCRAVNFWRGLSSNML
                     SRMMCDALHETDSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMMA
                     CRETMTSSAFREHIVELGAPEVSSLWHQQQKNPPFVLKHNLYEY"
     misc_feature    150530..150883
                     /locus_tag="ECOK1_0131"
                     /note="PTS_IIA, PTS system, mannose/sorbose specific IIA
                     subunit. The bacterial phosphoenolpyruvate: sugar
                     phosphotransferase system (PTS) is a multi-protein system
                     involved in the regulation of a variety of metabolic and
                     transcriptional processes. This family...; Region:
                     PTS_IIA_man; cd00006"
                     /db_xref="CDD:237978"
     misc_feature    order(150548..150550,150590..150595,150626..150628,
                     150734..150736,150827..150829)
                     /locus_tag="ECOK1_0131"
                     /note="active pocket/dimerization site"
                     /db_xref="CDD:237978"
     misc_feature    order(150548..150550,150719..150721,150734..150736)
                     /locus_tag="ECOK1_0131"
                     /note="active site"
                     /db_xref="CDD:237978"
     misc_feature    150548..150550
                     /locus_tag="ECOK1_0131"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:237978"
     gene            151028..152257
                     /locus_tag="ECOK1_0132"
                     /db_xref="GeneID:12688700"
     CDS             151028..152257
                     /locus_tag="ECOK1_0132"
                     /note="identified by match to protein family HMM PF01522"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase domain-containing
                     protein"
                     /protein_id="YP_006099387.1"
                     /db_xref="GI:386597881"
                     /db_xref="GeneID:12688700"
                     /translation="MYKQAVILLLMLFTASVSAALPARYMQTIENAAVWAQIGDKMVT
                     VGNIRAGQIIAVEPTAASYYVFNFGFGKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSN
                     QNLITRKDTPVYNAPSVGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
                     ALDAQPDNGLPVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMAQ
                     LEGYVKNKINLPARAVVITFDDGLKSVSRYAYPVLKQYGMKATAFIVTSRIKRHPQKW
                     NPKSLQFMSVSELNEIRDVFDFQSHTHFLHRIDGYRRPILLSRSEHNILFDFARSRRA
                     LAQFNPHVLYLSYPFGGFNDKAVKAAKEAGFHLAVTTMKGKVKPGDNPLLLKRLYILR
                     TDSLETMSRLVSNQPQG"
     misc_feature    151715..152224
                     /locus_tag="ECOK1_0132"
                     /note="Putative catalytic polysaccharide deacetylase
                     domain of uncharacterized protein yadE and similar
                     proteins; Region: CE4_yadE_5s; cd10966"
                     /db_xref="CDD:213024"
     misc_feature    order(151742..151747,151928..151930,151943..151945,
                     152069..152077)
                     /locus_tag="ECOK1_0132"
                     /note="putative active site [active]"
                     /db_xref="CDD:213024"
     misc_feature    order(151745..151747,151928..151930,151943..151945)
                     /locus_tag="ECOK1_0132"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:213024"
     gene            complement(152261..152641)
                     /gene="panD"
                     /locus_tag="ECOK1_0133"
                     /db_xref="GeneID:12688701"
     CDS             complement(152261..152641)
                     /gene="panD"
                     /locus_tag="ECOK1_0133"
                     /EC_number="4.1.1.11"
                     /note="identified by match to protein family HMM PF02261;
                     match to protein family HMM TIGR00223"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="YP_006099388.1"
                     /db_xref="GI:386597882"
                     /db_xref="GeneID:12688701"
                     /translation="MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWR
                     PNVAYFEGDNEMKRTAKAIPVQVA"
     misc_feature    complement(152306..152635)
                     /gene="panD"
                     /locus_tag="ECOK1_0133"
                     /note="Aspartate alpha-decarboxylase or L-aspartate
                     1-decarboxylase, a pyruvoyl group-dependent  decarboxylase
                     in beta-alanine production; Region: Asp_decarbox; cd06919"
                     /db_xref="CDD:132994"
     misc_feature    complement(order(152339..152341,152366..152374,
                     152384..152386,152408..152413,152417..152422,
                     152468..152482,152486..152488,152495..152497,
                     152501..152503,152513..152518,152525..152527,
                     152531..152533,152573..152584,152606..152611,
                     152615..152617,152621..152635))
                     /gene="panD"
                     /locus_tag="ECOK1_0133"
                     /note="tetramerization interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:132994"
     misc_feature    complement(order(152468..152470,152567..152572,
                     152609..152611,152615..152617))
                     /gene="panD"
                     /locus_tag="ECOK1_0133"
                     /note="active site"
                     /db_xref="CDD:132994"
     gene            152915..153799
                     /locus_tag="ECOK1_0134"
                     /db_xref="GeneID:12688702"
     CDS             152915..153799
                     /locus_tag="ECOK1_0134"
                     /note="identified by match to protein family HMM PF04754;
                     match to protein family HMM TIGR01784"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099389.1"
                     /db_xref="GI:386597883"
                     /db_xref="GeneID:12688702"
                     /translation="MDAPSTTPHDAVFKQFLMHAETARDFLDIHLPAELRELCDLDTL
                     HLESGSFIEESLKGHSTDVLYSVQMQGSTGYLHVVIEHQSKPDKKMAFRMMRYSIAAM
                     HRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDMFYSPELARRVYNSPFPLVDITI
                     TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSGSQLVAMQNYMLQR
                     GHTEQADLFYGVVRDRETGGESMMTLAQWFEEKGIQQGRQEVSQEFALRLLSKGMSRE
                     DVAEMANLPLAEIDKMIN"
     misc_feature    152933..153790
                     /locus_tag="ECOK1_0134"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG5464"
                     /db_xref="CDD:227751"
     misc_feature    152933..153538
                     /locus_tag="ECOK1_0134"
                     /note="Putative transposase, YhgA-like; Region:
                     Transposase_31; pfam04754"
                     /db_xref="CDD:252779"
     gene            complement(153881..154732)
                     /gene="panC"
                     /locus_tag="ECOK1_0135"
                     /db_xref="GeneID:12688703"
     CDS             complement(153881..154732)
                     /gene="panC"
                     /locus_tag="ECOK1_0135"
                     /EC_number="6.3.2.1"
                     /note="identified by match to protein family HMM PF02569;
                     match to protein family HMM TIGR00018; match to protein
                     family HMM TIGR00125"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="YP_006099390.1"
                     /db_xref="GI:386597884"
                     /db_xref="GeneID:12688703"
                     /translation="MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNG
                     TETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
                     KMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAG
                     ERDLDEIIAIAGQELNEKGFRSDDIQIRDADTLLEVSENSKRAVILVAAWLGDARLID
                     NKLVELA"
     misc_feature    complement(153902..154732)
                     /gene="panC"
                     /locus_tag="ECOK1_0135"
                     /note="Pantoate-beta-alanine ligase; Region: PanC;
                     cd00560"
                     /db_xref="CDD:185673"
     misc_feature    complement(order(154166..154177,154199..154207,
                     154268..154270,154277..154282,154286..154291,
                     154331..154336,154343..154345,154520..154522,
                     154550..154552,154559..154561,154613..154615,
                     154622..154627,154631..154633,154640..154651))
                     /gene="panC"
                     /locus_tag="ECOK1_0135"
                     /note="active site"
                     /db_xref="CDD:185673"
     misc_feature    complement(order(154175..154180,154199..154204,
                     154268..154270,154277..154282,154286..154291,
                     154331..154336,154550..154552,154613..154615,
                     154622..154624,154631..154633,154643..154651))
                     /gene="panC"
                     /locus_tag="ECOK1_0135"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:185673"
     misc_feature    complement(order(154268..154270,154322..154324,
                     154331..154336,154550..154552,154559..154561,
                     154643..154645,154649..154651))
                     /gene="panC"
                     /locus_tag="ECOK1_0135"
                     /note="pantoate-binding site; other site"
                     /db_xref="CDD:185673"
     misc_feature    complement(154622..154633)
                     /gene="panC"
                     /locus_tag="ECOK1_0135"
                     /note="HXXH motif; other site"
                     /db_xref="CDD:185673"
     gene            complement(154744..155538)
                     /gene="panB"
                     /locus_tag="ECOK1_0136"
                     /db_xref="GeneID:12688704"
     CDS             complement(154744..155538)
                     /gene="panB"
                     /locus_tag="ECOK1_0136"
                     /EC_number="2.1.2.11"
                     /note="identified by match to protein family HMM PF02548;
                     match to protein family HMM TIGR00222"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="YP_006099391.1"
                     /db_xref="GI:386597885"
                     /db_xref="GeneID:12688704"
                     /translation="MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFAEEGLNVMLVG
                     DSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAAT
                     VMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAG
                     DRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH"
     misc_feature    complement(154768..155523)
                     /gene="panB"
                     /locus_tag="ECOK1_0136"
                     /note="Ketopantoate hydroxymethyltransferase (KPHMT) is
                     the first enzyme in the pantothenate biosynthesis pathway.
                     Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes
                     the first committed step in the biosynthesis of
                     pantothenate (vitamin B5), which is a...; Region:
                     KPHMT-like; cd06557"
                     /db_xref="CDD:119342"
     misc_feature    complement(order(154816..154830,154837..154839,
                     154879..154884,154891..154893,155011..155013,
                     155095..155106,155110..155115,155143..155160,
                     155212..155214,155224..155229,155236..155238,
                     155248..155250,155275..155280,155317..155319,
                     155326..155328,155335..155340,155347..155349,
                     155362..155367,155377..155394,155398..155400,
                     155443..155445,155452..155463,155518..155523))
                     /gene="panB"
                     /locus_tag="ECOK1_0136"
                     /note="oligomerization interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:119342"
     misc_feature    complement(order(154897..154899,154903..154905,
                     154996..154998,155116..155118,155131..155133,
                     155203..155205,155287..155289,155401..155409,
                     155413..155415,155470..155472))
                     /gene="panB"
                     /locus_tag="ECOK1_0136"
                     /note="active site"
                     /db_xref="CDD:119342"
     misc_feature    complement(order(155203..155205,155287..155289,
                     155404..155406))
                     /gene="panB"
                     /locus_tag="ECOK1_0136"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:119342"
     gene            complement(155650..156915)
                     /locus_tag="ECOK1_0137"
                     /db_xref="GeneID:12688705"
     CDS             complement(155650..156915)
                     /locus_tag="ECOK1_0137"
                     /note="identified by match to protein family HMM PF00419"
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial protein"
                     /protein_id="YP_006099392.1"
                     /db_xref="GI:386597886"
                     /db_xref="GeneID:12688705"
                     /translation="MKIFFRYFLFLALCSCCYIASAGTDDHVGYVVGNNYGVGPSGQK
                     WRETGPNGDVTVKFRYGSVTNNLVFYKPTQLGPTGVSLKWAQLDSASGGGFLYCNRSG
                     STSGGPMHIENKMVDSGKSYGGHKLFKTSVPGLYYTLAISNIWSTYTYTDINPSGMYI
                     GDSTSQSFNWRGESEQTLYWSCNNANTKNKYWAVGGVMQTLTIEFYTDTDFNPTTNQR
                     VTLSRTDNYLYSFKAYGAGIGINDYSYFLKIDFDLTDIVLTNPTCFTAALSGSSVSGS
                     TVKMGDYTPAQIKNGATAVPFDITLQNCIRVRNIETKLKSNKVGSVSKELLANTLTGN
                     DAAKGVGVLIEGLKNTKSAQMVLKPNDATSIYKDYETEDDTTGGIYPDKGNGTSQPLH
                     FQATLKQDGNIAIEPGDFKATSTFQVTYP"
     misc_feature    complement(155653..156915)
                     /locus_tag="ECOK1_0137"
                     /note="putative fimbrial-like adhesin protein;
                     Provisional; Region: PRK09723"
                     /db_xref="CDD:236617"
     gene            complement(156965..157561)
                     /locus_tag="ECOK1_0138"
                     /db_xref="GeneID:12688706"
     CDS             complement(156965..157561)
                     /locus_tag="ECOK1_0138"
                     /note="identified by similarity to GB:CAD01338.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099393.1"
                     /db_xref="GI:386597887"
                     /db_xref="GeneID:12688706"
                     /translation="MRPTQRNLMKKSILLLSLLFSATSPVVAGQDVDIVANIKNNTCQ
                     SGISNNGNIDLGVVGVGDFTGNISAENYHPGGKEFTITVQDCTLQGTGNVLNQLHINF
                     RALSGVMATGSSQIFANEDNAGAKNVGVVIFSIQDPANTFNVLSATGSSRSVYPVMSS
                     ALNNSSWKFSTRMQKIDPALNVTSGPLISHVLVDIYYE"
     misc_feature    complement(156968..157552)
                     /locus_tag="ECOK1_0138"
                     /note="putative fimbrial protein StaF; Provisional;
                     Region: PRK15262"
                     /db_xref="CDD:237933"
     gene            complement(157588..158196)
                     /locus_tag="ECOK1_0139"
                     /db_xref="GeneID:12688707"
     CDS             complement(157588..158196)
                     /locus_tag="ECOK1_0139"
                     /note="identified by match to protein family HMM PF00419"
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial protein"
                     /protein_id="YP_006099394.1"
                     /db_xref="GI:386597888"
                     /db_xref="GeneID:12688707"
                     /translation="MMILKKLCYGLSGSLFLASSLLTISSHAATDSIGLTVTTDVEMG
                     TCTSTLTDDGTTKISTINFGDVYISEINAETKIKTFKLQFKDCAGIPGKKAKIKLTTR
                     ALCEGNSNNGPGFANASTATAKAAAVAVEVWSTSTPGKNGAKQFSCVTPATEEVSIAN
                     ATGSNVVDYPMSAVLVVAKDKTVTNVTAGDFTAPATFTVTYN"
     misc_feature    complement(157591..158178)
                     /locus_tag="ECOK1_0139"
                     /note="putative fimbrial protein StaE; Provisional;
                     Region: PRK15263"
                     /db_xref="CDD:185171"
     gene            complement(158208..158774)
                     /locus_tag="ECOK1_0140"
                     /db_xref="GeneID:12688708"
     CDS             complement(158208..158774)
                     /locus_tag="ECOK1_0140"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099395.1"
                     /db_xref="GI:386597889"
                     /db_xref="GeneID:12688708"
                     /translation="MIKITPHKITILMGLLLSPSVFATDVNVDFTATVKATTCNITLT
                     GTNVTDNGKDKYTLVIPSMGMDKIANKTAQSEANFKLVANGCSSGISWIDTTLTGNQS
                     GSSPALIIPLASDTTSTTSYIGMGFKRKATSGDTFLKPNSAEYIRWSASEISTDGLEM
                     TVALRETSVGKGVPGKFRALATFNFSYQ"
     misc_feature    complement(158211..158708)
                     /locus_tag="ECOK1_0140"
                     /note="Fimbrial protein; Region: Fimbrial; cl01416"
                     /db_xref="CDD:260929"
     gene            complement(158791..161379)
                     /locus_tag="ECOK1_0141"
                     /db_xref="GeneID:12688709"
     CDS             complement(158791..161379)
                     /locus_tag="ECOK1_0141"
                     /note="identified by match to protein family HMM PF00577"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane usher protein"
                     /protein_id="YP_006099396.1"
                     /db_xref="GI:386597890"
                     /db_xref="GeneID:12688709"
                     /translation="MTIKSTNHLTHIATFCALLYSNSALCAELVEYDHTFLMGKDASN
                     IDLSRYTEGNPTLPGIYDVSVYVNDQPIMSQSIAFAVIEGKKNAQACITQKNLLQFHI
                     SSPDKNSEKAILLKRDDDLGDCLNLAEMIPQSSIRYDVNDQRLDIDVPQAWIMKNYQN
                     YVDPSLWENGINAAMLSYNLNGYHSESPGRTNDSIYAAFNGGINLGAWRLRASGNYNW
                     MTNVHSDYDFQNRYLQRDLASLRSQLVIGESYTTGETFDSVRIRGIRLYSDSRMLPPV
                     LASFAPIIHGVANTNAKVTVMQNGYKIYETTVPPGAFAIDDLSPSGYGSDLIVTIEEA
                     DGTKRTFSQPFSSVVQMLRPGVGRWDISAGQVLKDSIQDEPNLFQASYYYGLNNYLTG
                     YTGIQLTDNNYTAGLLGLGMNTPVGAFSVDVTHSNVSIPDDKTYQGQSYRISWNKLFE
                     NTSTSLNIAAYRYSTQHYLGLNDALTLIDEVEHPEQDLEPKSMRNYSRMKNQVTVSIN
                     QPLKFEKKDYGSFYLSGSWSDYWASGQNSTNYSIGYSNSASWGSYSISAQRSLNEDGQ
                     TDDSIYLSFTIPIENLLGTEHRSSGFQSIDTQLNSDFKGNNQLNISSSGYSDTNRISY
                     SVNTGYMMNKSSDDLSYIGGYASYESPWGTLSGSASASSDNSRQFSLNTDGGFVLHSG
                     GLTFSNDSFSDSDTLAVIQAPGAKGARINYGNSTVDRWGYGVTSALSPYHENRIALDI
                     NDLENDVELKSTSTVAVPRQGAVVFADFETVQGQSAIMNIVRSDGKNIPFAADIYDEQ
                     NNIIGNVGQGGQAFVRGIGQEGNIRITWIEEGKPVSCFAHYQQNTTSEKIAQSIILNG
                     LRCQIQ"
     misc_feature    complement(158794..161379)
                     /locus_tag="ECOK1_0141"
                     /note="putative fimbrial outer membrane usher protein;
                     Provisional; Region: PRK09828"
                     /db_xref="CDD:182098"
     misc_feature    complement(160831..161292)
                     /locus_tag="ECOK1_0141"
                     /note="PapC N-terminal domain; Region: PapC_N; pfam13954"
                     /db_xref="CDD:258209"
     misc_feature    complement(159076..160794)
                     /locus_tag="ECOK1_0141"
                     /note="Outer membrane usher protein; Region: Usher;
                     pfam00577"
                     /db_xref="CDD:249973"
     misc_feature    complement(158842..159048)
                     /locus_tag="ECOK1_0141"
                     /note="PapC C-terminal domain; Region: PapC_C; pfam13953"
                     /db_xref="CDD:258208"
     gene            complement(161414..162154)
                     /locus_tag="ECOK1_0142"
                     /db_xref="GeneID:12688710"
     CDS             complement(161414..162154)
                     /locus_tag="ECOK1_0142"
                     /note="identified by match to protein family HMM PF00345;
                     match to protein family HMM PF02753"
                     /codon_start=1
                     /transl_table=11
                     /product="pili assembly chaperone"
                     /protein_id="YP_006099397.1"
                     /db_xref="GI:386597891"
                     /db_xref="GeneID:12688710"
                     /translation="MFFNTKHTAALCLASCMAFSSSAIADIVISGTRVVYKSEQKSVN
                     VRLENKGNNPLLVQSWLDTGDDNAEPGSITVPFTATPPVSRIDAKRGQTIKLMYTASS
                     ALPKDRESVFWFNVLEVPPKPDAAKAANQSLLQLAFRTRIKLFYRPEGLSGISSDAPL
                     ALKWSWATSEGKAALRVDNPTPYYVSFSSGDLEANGKRYPLDMTMIAPFSNDVIKVNG
                     MSGRTSSAKVHFFAINDFGGSIEGNANL"
     misc_feature    complement(161417..162154)
                     /locus_tag="ECOK1_0142"
                     /note="putative chaperone protein EcpD; Provisional;
                     Region: PRK09926"
                     /db_xref="CDD:236634"
     misc_feature    complement(161699..162076)
                     /locus_tag="ECOK1_0142"
                     /note="Pili and flagellar-assembly chaperone, PapD
                     N-terminal domain; Region: PapD_N; pfam00345"
                     /db_xref="CDD:249787"
     misc_feature    complement(161429..161632)
                     /locus_tag="ECOK1_0142"
                     /note="Pili assembly chaperone PapD, C-terminal domain;
                     Region: PapD_C; pfam02753"
                     /db_xref="CDD:251514"
     gene            complement(162263..162853)
                     /locus_tag="ECOK1_0143"
                     /db_xref="GeneID:12688711"
     CDS             complement(162263..162853)
                     /locus_tag="ECOK1_0143"
                     /note="identified by similarity to SP:P08190; match to
                     protein family HMM PF00419"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="YP_006099398.1"
                     /db_xref="GI:386597892"
                     /db_xref="GeneID:12688711"
                     /translation="MSKKLGFALSGIMLAMAAGTAFAANDMDGGQLNISGLVVDNTCE
                     ARVDGGNKDGLILLQTATVAEITDGVLDTTVGAKAKPFSITIDCSKANPAPGTTAKMT
                     FGSVFFGNSKGTLNNDMSINTPSDGVNIALHNIEGSTIKQVQVNNPGDVYSKTLDSTS
                     KSATYDFKASYVRADASKAATAGYVKTNSAYTITYQ"
     misc_feature    complement(162266..162775)
                     /locus_tag="ECOK1_0143"
                     /note="Fimbrial protein; Region: Fimbrial; cl01416"
                     /db_xref="CDD:260929"
     gene            complement(163215..163694)
                     /gene="folK"
                     /locus_tag="ECOK1_0144"
                     /db_xref="GeneID:12688712"
     CDS             complement(163215..163694)
                     /gene="folK"
                     /locus_tag="ECOK1_0144"
                     /EC_number="2.7.6.3"
                     /note="identified by similarity to SP:P26281; match to
                     protein family HMM PF01288; match to protein family HMM
                     TIGR01498"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine pyrophosphokinase"
                     /protein_id="YP_006099399.1"
                     /db_xref="GI:386597893"
                     /db_xref="GeneID:12688712"
                     /translation="MTVAYIAIGSNLASPLEQVNAALKALGDIPESRILAVSSFYRTP
                     PLGPQDQPDYLNAAVALKTTLAPEGLLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
                     GNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGLSLVEALQAKGFNELDKW"
     misc_feature    complement(163299..163685)
                     /gene="folK"
                     /locus_tag="ECOK1_0144"
                     /note="7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
                     (HPPK). Folate derivatives are essential cofactors in the
                     biosynthesis of purines, pyrimidines, and amino acids as
                     well as formyl-tRNA. Mammalian cells are able to utilize
                     pre-formed folates after...; Region: HPPK; cd00483"
                     /db_xref="CDD:238269"
     misc_feature    complement(order(163323..163325,163329..163331,
                     163344..163349,163356..163358,163398..163403,
                     163407..163409,163416..163418,163425..163427,
                     163440..163442,163446..163448,163461..163463,
                     163470..163472,163482..163484,163527..163529,
                     163533..163535,163557..163559,163563..163568,
                     163668..163670))
                     /gene="folK"
                     /locus_tag="ECOK1_0144"
                     /note="catalytic center binding site [active]"
                     /db_xref="CDD:238269"
     misc_feature    complement(order(163329..163331,163344..163349,
                     163356..163358,163398..163403,163416..163418,
                     163440..163442,163446..163448,163461..163463,
                     163470..163472,163482..163484))
                     /gene="folK"
                     /locus_tag="ECOK1_0144"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238269"
     gene            complement(163691..165055)
                     /gene="pcnB"
                     /locus_tag="ECOK1_0145"
                     /db_xref="GeneID:12688713"
     CDS             complement(163691..165055)
                     /gene="pcnB"
                     /locus_tag="ECOK1_0145"
                     /EC_number="2.7.7.19"
                     /note="identified by match to protein family HMM PF01743;
                     match to protein family HMM TIGR01942"
                     /codon_start=1
                     /transl_table=11
                     /product="poly(A) polymerase"
                     /protein_id="YP_006099400.1"
                     /db_xref="GI:386597894"
                     /db_xref="GeneID:12688713"
                     /translation="MLSREESEAEQAVARPQVTVIPREQHAISRKDISENALKVMYRL
                     NKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKLFRNCRLVGRRFRLAHVMF
                     GPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYS
                     VADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLRAVRFAAKLGMRISPETAE
                     PIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFPTITRYFTENG
                     DSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLETAQKIAQESGLTYHDAF
                     ALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLLEHPKFRAAYDL
                     LALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDEEPSPRRRTRRPRKRAPRR
                     EGTA"
     misc_feature    complement(163757..165055)
                     /gene="pcnB"
                     /locus_tag="ECOK1_0145"
                     /note="poly(A) polymerase I; Provisional; Region: pcnB;
                     PRK11623"
                     /db_xref="CDD:236939"
     misc_feature    complement(164522..164956)
                     /gene="pcnB"
                     /locus_tag="ECOK1_0145"
                     /note="Nucleotidyltransferase (NT) domain of ClassII
                     CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398"
                     /db_xref="CDD:143388"
     misc_feature    complement(order(164591..164593,164600..164611,
                     164717..164719,164732..164734,164771..164773,
                     164843..164845,164849..164851,164876..164881,
                     164888..164893))
                     /gene="pcnB"
                     /locus_tag="ECOK1_0145"
                     /note="active site"
                     /db_xref="CDD:143388"
     misc_feature    complement(order(164591..164593,164603..164611,
                     164843..164845,164849..164851,164879..164881,
                     164888..164893))
                     /gene="pcnB"
                     /locus_tag="ECOK1_0145"
                     /note="NTP binding site [chemical binding]; other site"
                     /db_xref="CDD:143388"
     misc_feature    complement(order(164732..164734,164843..164845,
                     164849..164851))
                     /gene="pcnB"
                     /locus_tag="ECOK1_0145"
                     /note="metal binding triad [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143388"
     misc_feature    complement(164240..164431)
                     /gene="pcnB"
                     /locus_tag="ECOK1_0145"
                     /note="Probable RNA and SrmB- binding site of polymerase
                     A; Region: PolyA_pol_RNAbd; pfam12627"
                     /db_xref="CDD:257174"
     misc_feature    complement(163757..164086)
                     /gene="pcnB"
                     /locus_tag="ECOK1_0145"
                     /note="Polymerase A arginine-rich C-terminus; Region:
                     PolyA_pol_arg_C; pfam12626"
                     /db_xref="CDD:257173"
     gene            complement(165148..166074)
                     /gene="gluQ"
                     /locus_tag="ECOK1_0146"
                     /db_xref="GeneID:12688714"
     CDS             complement(165148..166074)
                     /gene="gluQ"
                     /locus_tag="ECOK1_0146"
                     /EC_number="6.1.1.-"
                     /note="identified by match to protein family HMM PF00749;
                     match to protein family HMM TIGR03838"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-queuosine tRNA(Asp) synthetase"
                     /protein_id="YP_006099401.1"
                     /db_xref="GI:386597895"
                     /db_xref="GeneID:12688714"
                     /translation="MLPPYFLFKEMTDTHYIGRFAPSPSGELHFGSLIAALGSYLQAR
                     ARQGRWLVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHHAYREALAWL
                     HEQGLSYYCTCTRARIQSIGGIYDGHCRDLHHGPDNAAVRIRQQHPVTQFTDLLRGII
                     HADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVSEIVRGADLIEPTVRQISLYQLF
                     GWKVPDYIHLPLALNPQGAKLSKQNHAPALPKGDPRPVLIAALHFLGQQVETHWQDFS
                     VEQILQSAVKNWTLTAVPESAIVNSTFSNASC"
     misc_feature    complement(165166..166044)
                     /gene="gluQ"
                     /locus_tag="ECOK1_0146"
                     /note="glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region:
                     PRK05710"
                     /db_xref="CDD:235573"
     misc_feature    complement(165184..166020)
                     /gene="gluQ"
                     /locus_tag="ECOK1_0146"
                     /note="tRNA synthetases class I (E and Q), catalytic
                     domain; Region: tRNA-synt_1c; pfam00749"
                     /db_xref="CDD:250104"
     misc_feature    complement(order(165352..165357,165979..165990))
                     /gene="gluQ"
                     /locus_tag="ECOK1_0146"
                     /note="active site"
                     /db_xref="CDD:173912"
     misc_feature    complement(order(165352..165354,165979..165981,
                     165988..165990))
                     /gene="gluQ"
                     /locus_tag="ECOK1_0146"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173912"
     misc_feature    complement(165979..165990)
                     /gene="gluQ"
                     /locus_tag="ECOK1_0146"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173912"
     misc_feature    complement(165352..165357)
                     /gene="gluQ"
                     /locus_tag="ECOK1_0146"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:173912"
     gene            complement(166111..166566)
                     /gene="dksA"
                     /locus_tag="ECOK1_0147"
                     /db_xref="GeneID:12688715"
     CDS             complement(166111..166566)
                     /gene="dksA"
                     /locus_tag="ECOK1_0147"
                     /note="identified by match to protein family HMM PF01258;
                     match to protein family HMM TIGR02420"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="YP_006099402.1"
                     /db_xref="GI:386597896"
                     /db_xref="GeneID:12688715"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     misc_feature    complement(166114..166566)
                     /gene="dksA"
                     /locus_tag="ECOK1_0147"
                     /note="RNA polymerase-binding transcription factor;
                     Provisional; Region: dksA; PRK10778"
                     /db_xref="CDD:182722"
     gene            complement(166744..167448)
                     /gene="sfsA"
                     /locus_tag="ECOK1_0148"
                     /db_xref="GeneID:12688716"
     CDS             complement(166744..167448)
                     /gene="sfsA"
                     /locus_tag="ECOK1_0148"
                     /note="identified by match to protein family HMM PF03749;
                     match to protein family HMM TIGR00230"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar fermentation stimulation protein"
                     /protein_id="YP_006099403.1"
                     /db_xref="GI:386597897"
                     /db_xref="GeneID:12688716"
                     /translation="MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGC
                     ATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAIICVNTLWANRLTKEAILNESISELA
                     GYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
                     LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAE
                     LSAEGMALKKSLPVTL"
     misc_feature    complement(166747..167448)
                     /gene="sfsA"
                     /locus_tag="ECOK1_0148"
                     /note="putative DNA-binding transcriptional regulator;
                     Reviewed; Region: PRK00347"
                     /db_xref="CDD:234733"
     gene            complement(167463..167993)
                     /gene="ligT"
                     /locus_tag="ECOK1_0149"
                     /db_xref="GeneID:12688717"
     CDS             complement(167463..167993)
                     /gene="ligT"
                     /locus_tag="ECOK1_0149"
                     /EC_number="6.5.1.-"
                     /note="identified by match to protein family HMM PF02834;
                     match to protein family HMM TIGR02258"
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase"
                     /protein_id="YP_006099404.1"
                     /db_xref="GI:386597898"
                     /db_xref="GeneID:12688717"
                     /translation="MSEPQRLFFAIDLPAEIREQIIRWRATHFPPEAGRPVAADNLHL
                     TLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
                     ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYTVTEFTLYASSFA
                     RGRTRYTPLKRWALTQ"
     misc_feature    complement(167466..167993)
                     /gene="ligT"
                     /locus_tag="ECOK1_0149"
                     /note="2'-5' RNA ligase; Provisional; Region: PRK15124"
                     /db_xref="CDD:185079"
     misc_feature    complement(167727..167963)
                     /gene="ligT"
                     /locus_tag="ECOK1_0149"
                     /note="LigT like Phosphoesterase; Region: LigT_PEase;
                     pfam02834"
                     /db_xref="CDD:251562"
     misc_feature    complement(167496..167720)
                     /gene="ligT"
                     /locus_tag="ECOK1_0149"
                     /note="LigT like Phosphoesterase; Region: LigT_PEase;
                     pfam02834"
                     /db_xref="CDD:251562"
     gene            168022..170496
                     /gene="hrpB"
                     /locus_tag="ECOK1_0150"
                     /db_xref="GeneID:12688718"
     CDS             168022..170496
                     /gene="hrpB"
                     /locus_tag="ECOK1_0150"
                     /note="identified by match to protein family HMM PF00270;
                     match to protein family HMM PF00271; match to protein
                     family HMM PF04408; match to protein family HMM PF08482;
                     match to protein family HMM TIGR01970"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase HrpB"
                     /protein_id="YP_006099405.1"
                     /db_xref="GI:386597899"
                     /db_xref="GeneID:12688718"
                     /translation="MLQCGAKNVNPLERFVSSLPVAAVLPELLAALDGASQVLLSAPT
                     GAGKSTWLPLQLLAHPGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQ
                     NCVGPNTRLEVVTEGVLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQG
                     LRDDLKLLIMSATLDNDRLQQMLPEAPVVISEGRSFPVERRYLPLPAHQRFDEAVAVA
                     TAEMLRQESGSLLLFLPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPA
                     PQGMRKVVLATNIAETSLTIEGIRLVVDCAQERVARFDPRTGLTRLVTQRVSQASMTQ
                     RAGRAGRLEPGICLHLIAKEQAERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQMSW
                     LDQPPTVNLLAAKRLLRMLGALDGERLSAQGQKMATLGNDPRLAAMLVSAKNDDEAAT
                     AAKIAAILEEPPRMGNSDLGVAFSRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPLLA
                     RAYADRIARRRGQDERYQLANGMGAMLDADDALSRHEWLIAPLLLQGSASPDARILLA
                     LPVDIDELVQRCPQLVQQSDTVEWDDAQGTLKAWRRLQIGQLMVKVQPLAKPSEDELH
                     QAMLNGIRDKGLSVLNWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLATLETWLLP
                     HMTGVHSLRGLKSLDIYQALRGLLDWVMQQRLDSELPAHYTVPTGSRIAIRYHEDNPP
                     ALAVRMQEMFGEATNPTIAQGRVPLVLELLSPAQRPLQITRDLSAFWKGAYREVQKEM
                     KGRYPKHVWPDDPANTAPTRRTKKYS"
     misc_feature    168067..170493
                     /gene="hrpB"
                     /locus_tag="ECOK1_0150"
                     /note="ATP-dependent RNA helicase HrpB; Provisional;
                     Region: PRK11664"
                     /db_xref="CDD:236950"
     misc_feature    168133..168543
                     /gene="hrpB"
                     /locus_tag="ECOK1_0150"
                     /note="DEAD-like helicases superfamily. A diverse family
                     of proteins involved in ATP-dependent RNA or DNA
                     unwinding. This domain contains the ATP-binding region;
                     Region: DEXDc; cd00046"
                     /db_xref="CDD:238005"
     misc_feature    168154..168168
                     /gene="hrpB"
                     /locus_tag="ECOK1_0150"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238005"
     misc_feature    168433..168444
                     /gene="hrpB"
                     /locus_tag="ECOK1_0150"
                     /note="putative Mg++ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238005"
     misc_feature    168682..169071
                     /gene="hrpB"
                     /locus_tag="ECOK1_0150"
                     /note="Helicase superfamily c-terminal domain; associated
                     with DEXDc-, DEAD-, and DEAH-box proteins, yeast
                     initiation factor 4A, Ski2p, and Hepatitis C virus NS3
                     helicases; this domain is found in a wide variety of
                     helicases and helicase related proteins; may...; Region:
                     HELICc; cd00079"
                     /db_xref="CDD:238034"
     misc_feature    order(168724..168735,168802..168807,168880..168888)
                     /gene="hrpB"
                     /locus_tag="ECOK1_0150"
                     /note="nucleotide binding region [chemical binding]; other
                     site"
                     /db_xref="CDD:238034"
     misc_feature    order(168904..168906,169021..169023,169033..169035,
                     169042..169044)
                     /gene="hrpB"
                     /locus_tag="ECOK1_0150"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238034"
     misc_feature    169249..>169350
                     /gene="hrpB"
                     /locus_tag="ECOK1_0150"
                     /note="Helicase associated domain (HA2) Add an annotation;
                     Region: HA2; smart00847"
                     /db_xref="CDD:214852"
     misc_feature    170056..170454
                     /gene="hrpB"
                     /locus_tag="ECOK1_0150"
                     /note="ATP-dependent helicase C-terminal; Region: HrpB_C;
                     pfam08482"
                     /db_xref="CDD:254823"
     gene            170590..173124
                     /gene="mrcB"
                     /locus_tag="ECOK1_0151"
                     /db_xref="GeneID:12688719"
     CDS             170590..173124
                     /gene="mrcB"
                     /locus_tag="ECOK1_0151"
                     /EC_number="2.4.1.129"
                     /EC_number="3.4.-.-"
                     /note="identified by similarity to SP:P02919; match to
                     protein family HMM PF00905; match to protein family HMM
                     PF00912; match to protein family HMM TIGR02071"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1B"
                     /protein_id="YP_006099406.1"
                     /db_xref="GI:386597900"
                     /db_xref="GeneID:12688719"
                     /translation="MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEE
                     PMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQL
                     PAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
                     FPDSKEGQVRACLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPR
                     SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNL
                     FLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYY
                     FGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYD
                     MLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAA
                     EKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSI
                     GSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLV
                     DALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLNPVPAMLLGALNLTPIEVAQA
                     FQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGT
                     GRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAM
                     SIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRVLPVWTSDPQSLCQQSE
                     MQQQPSGNPFDQSSQPQQQPQQQPAQQEQKDSDGVAGWIKDMFGSN"
     misc_feature    170590..173118
                     /gene="mrcB"
                     /locus_tag="ECOK1_0151"
                     /note="bifunctional glycosyl transferase/transpeptidase;
                     Reviewed; Region: mrcB; PRK09506"
                     /db_xref="CDD:236544"
     misc_feature    170590..170826
                     /gene="mrcB"
                     /locus_tag="ECOK1_0151"
                     /note="Transmembrane domain of transglycosylase PBP1 at
                     N-terminal; Region: PBP1_TM; pfam14812"
                     /db_xref="CDD:258949"
     misc_feature    170926..171180
                     /gene="mrcB"
                     /locus_tag="ECOK1_0151"
                     /note="Bifunctional transglycosylase second domain;
                     Region: UB2H; pfam14814"
                     /db_xref="CDD:258951"
     misc_feature    171196..171711
                     /gene="mrcB"
                     /locus_tag="ECOK1_0151"
                     /note="Transglycosylase; Region: Transgly; pfam00912"
                     /db_xref="CDD:250219"
     misc_feature    172006..172731
                     /gene="mrcB"
                     /locus_tag="ECOK1_0151"
                     /note="Penicillin binding protein transpeptidase domain;
                     Region: Transpeptidase; cl17760"
                     /db_xref="CDD:266819"
     gene            complement(173189..173344)
                     /locus_tag="ECOK1_0152"
                     /db_xref="GeneID:12688720"
     CDS             complement(173189..173344)
                     /locus_tag="ECOK1_0152"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099407.1"
                     /db_xref="GI:386597901"
                     /db_xref="GeneID:12688720"
                     /translation="MVFLWCKVNDNVNENDYYKDEIIFETLAGSQAVRNLRIPEGSIN
                     NQMKRKG"
     gene            173344..175587
                     /gene="fhuA"
                     /locus_tag="ECOK1_0153"
                     /db_xref="GeneID:12688721"
     CDS             173344..175587
                     /gene="fhuA"
                     /locus_tag="ECOK1_0153"
                     /note="identified by similarity to SP:P06971; match to
                     protein family HMM PF00593; match to protein family HMM
                     PF07715; match to protein family HMM TIGR01783"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome-iron receptor"
                     /protein_id="YP_006099408.1"
                     /db_xref="GI:386597902"
                     /db_xref="GeneID:12688721"
                     /translation="MAPSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITV
                     TAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEA
                     LSYTPGVSVGTRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLE
                     RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDALD
                     DDGVYSYRLTGLARSANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGY
                     YGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLR
                     FAENKTSQNSVYGYGVCSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDT
                     QLQSKFATGDIDHTLLTGVDFMRMRNDINAWFGYDDSVPLLDLYNPVNTDFDFNAKDP
                     DNSGPYRILNKQKQTGVYVQDQAQWDKVLVTLGGRYDWADQESLNRVAGTTDKRDDKQ
                     FTWRGGVNYLFDNGVTPYFSYSESFEPSSQVGKDGNIFAPSKGKQYEVGVKYVPEDRP
                     IVVTGAVYNLTKTNNLMADPEGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYT
                     DAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANS
                     FKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQVV
                     ATATFRF"
     misc_feature    173344..175584
                     /gene="fhuA"
                     /locus_tag="ECOK1_0153"
                     /note="ferrichrome outer membrane transporter;
                     Provisional; Region: PRK10044"
                     /db_xref="CDD:236643"
     misc_feature    173587..175584
                     /gene="fhuA"
                     /locus_tag="ECOK1_0153"
                     /note="TonB dependent/Ligand-Gated channels are created by
                     a monomeric 22 strand (22,24) anti-parallel beta-barrel.
                     Ligands apparently bind to the large extracellular loops.
                     The N-terminal 150-200 residues form a plug from the
                     periplasmic end of barrel; Region: ligand_gated_channel;
                     cd01347"
                     /db_xref="CDD:238657"
     misc_feature    order(173587..173616,173644..173673,173710..173727,
                     173746..173748,173755..173775,173809..173841,
                     173875..173901)
                     /gene="fhuA"
                     /locus_tag="ECOK1_0153"
                     /note="N-terminal plug; other site"
                     /db_xref="CDD:238657"
     misc_feature    order(174361..174363,174490..174492)
                     /gene="fhuA"
                     /locus_tag="ECOK1_0153"
                     /note="ligand-binding site [chemical binding]; other site"
                     /db_xref="CDD:238657"
     gene            175638..176435
                     /gene="fhuC"
                     /locus_tag="ECOK1_0154"
                     /db_xref="GeneID:12688722"
     CDS             175638..176435
                     /gene="fhuC"
                     /locus_tag="ECOK1_0154"
                     /note="identified by similarity to SP:P07821; match to
                     protein family HMM PF00005"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome ABC transporter ATP-binding protein"
                     /protein_id="YP_006099409.1"
                     /db_xref="GI:386597903"
                     /db_xref="GeneID:12688722"
                     /translation="MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIG
                     HNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV
                     RELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYL
                     VALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY"
     misc_feature    175638..176432
                     /gene="fhuC"
                     /locus_tag="ECOK1_0154"
                     /note="iron-hydroxamate transporter ATP-binding subunit;
                     Provisional; Region: PRK10575"
                     /db_xref="CDD:182561"
     misc_feature    175674..176327
                     /gene="fhuC"
                     /locus_tag="ECOK1_0154"
                     /note="ATP-binding component of iron-siderophores, vitamin
                     B12 and hemin transporters and related proteins; Region:
                     ABC_Iron-Siderophores_B12_Hemin; cd03214"
                     /db_xref="CDD:213181"
     misc_feature    175767..175790
                     /gene="fhuC"
                     /locus_tag="ECOK1_0154"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213181"
     misc_feature    order(175776..175781,175785..175793,175911..175913,
                     176151..176156,176253..176255)
                     /gene="fhuC"
                     /locus_tag="ECOK1_0154"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213181"
     misc_feature    175902..175913
                     /gene="fhuC"
                     /locus_tag="ECOK1_0154"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213181"
     misc_feature    176079..176108
                     /gene="fhuC"
                     /locus_tag="ECOK1_0154"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213181"
     misc_feature    176139..176156
                     /gene="fhuC"
                     /locus_tag="ECOK1_0154"
                     /note="Walker B; other site"
                     /db_xref="CDD:213181"
     misc_feature    176163..176174
                     /gene="fhuC"
                     /locus_tag="ECOK1_0154"
                     /note="D-loop; other site"
                     /db_xref="CDD:213181"
     misc_feature    176241..176261
                     /gene="fhuC"
                     /locus_tag="ECOK1_0154"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213181"
     gene            176435..177325
                     /gene="fhuD"
                     /locus_tag="ECOK1_0155"
                     /db_xref="GeneID:12688723"
     CDS             176435..177325
                     /gene="fhuD"
                     /locus_tag="ECOK1_0155"
                     /note="identified by similarity to SP:P07822; match to
                     protein family HMM PF01497"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome ABC transporter, periplasmic
                     ferrichrome-binding protein"
                     /protein_id="YP_006099410.1"
                     /db_xref="GI:386597904"
                     /db_xref="GeneID:12688723"
                     /translation="MSGLPLISRRRLLTAMALSPLLWQMNTAHAAVIDPNRIVALEWL
                     PVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAHYED
                     FIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWG
                     STAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYG
                     ATLSAMHFVRILDNAIGGKA"
     misc_feature    176534..177289
                     /gene="fhuD"
                     /locus_tag="ECOK1_0155"
                     /note="Fe3+-siderophore binding domain FhuD.  These
                     proteins have been shown to function as initial receptors
                     in ABC transport of Fe3+-siderophores in many eubacterial
                     species. They belong to the TroA-like superfamily of
                     helical backbone metal receptor proteins...; Region: FhuD;
                     cd01146"
                     /db_xref="CDD:238566"
     misc_feature    176546..177253
                     /gene="fhuD"
                     /locus_tag="ECOK1_0155"
                     /note="Periplasmic binding protein; Region: Peripla_BP_2;
                     pfam01497"
                     /db_xref="CDD:250662"
     misc_feature    order(176636..176638,176684..176689,176750..176752,
                     176999..177001)
                     /gene="fhuD"
                     /locus_tag="ECOK1_0155"
                     /note="siderophore binding site; other site"
                     /db_xref="CDD:238566"
     gene            177322..179304
                     /gene="fhuB"
                     /locus_tag="ECOK1_0156"
                     /db_xref="GeneID:12688724"
     CDS             177322..179304
                     /gene="fhuB"
                     /locus_tag="ECOK1_0156"
                     /note="identified by similarity to SP:P06972; match to
                     protein family HMM PF01032"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome ABC transporter permease FhuB"
                     /protein_id="YP_006099411.1"
                     /db_xref="GI:386597905"
                     /db_xref="GeneID:12688724"
                     /translation="MSKRIALFPVLLLALLVVAAAALTWMNFSQALPRSQWAQAAWSP
                     DIDVIEQMIFHYSLLPRLAISLLVGAGLGLVGVLFQQVLRNPLAEPTTLGVATGAQLG
                     ITVTTLWAIPGAMASQFAALAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
                     NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLD
                     DGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPR
                     LMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDM
                     KVNDRVATERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWP
                     RIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWL
                     LPAGSLGAAVTLLIIMIAAGRGGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQV
                     LTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGMALTPTR
                     IALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFA
                     DWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR"
     misc_feature    177322..179301
                     /gene="fhuB"
                     /locus_tag="ECOK1_0156"
                     /note="iron-hydroxamate transporter permease subunit;
                     Provisional; Region: PRK10577"
                     /db_xref="CDD:236720"
     misc_feature    177505..178269
                     /gene="fhuB"
                     /locus_tag="ECOK1_0156"
                     /note="Transmembrane subunit (TM), of Periplasmic Binding
                     Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters involved in the uptake of siderophores, heme,
                     vitamin B12, or the divalent cations Mg2+ and Zn2+.
                     PBP-dependent ABC transporters consist of...; Region:
                     TM_ABC_iron-siderophores_like; cd06550"
                     /db_xref="CDD:119348"
     misc_feature    order(177559..177561,177571..177579,177937..177942,
                     177946..177954,177958..177963,177967..177984,
                     177988..177996,178117..178119,178138..178140)
                     /gene="fhuB"
                     /locus_tag="ECOK1_0156"
                     /note="ABC-ATPase subunit  interface; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(177574..177576,177580..177582,177595..177597,
                     177754..177756,177760..177765,177772..177777,
                     177784..177789,177796..177798,177805..177810,
                     177814..177816,177847..177852,177859..177861,
                     178087..178089,178246..178248,178255..178260,
                     178267..178269)
                     /gene="fhuB"
                     /locus_tag="ECOK1_0156"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(177814..177816,177889..177891,178063..178065,
                     178075..178077,178207..178209,178237..178239)
                     /gene="fhuB"
                     /locus_tag="ECOK1_0156"
                     /note="putative PBP binding regions; other site"
                     /db_xref="CDD:119348"
     misc_feature    178501..179286
                     /gene="fhuB"
                     /locus_tag="ECOK1_0156"
                     /note="Transmembrane subunit (TM), of Periplasmic Binding
                     Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters involved in the uptake of siderophores, heme,
                     vitamin B12, or the divalent cations Mg2+ and Zn2+.
                     PBP-dependent ABC transporters consist of...; Region:
                     TM_ABC_iron-siderophores_like; cd06550"
                     /db_xref="CDD:119348"
     misc_feature    order(178555..178557,178567..178575,178936..178941,
                     178945..178953,178957..178962,178966..178983,
                     178987..178995,179116..179118,179137..179139)
                     /gene="fhuB"
                     /locus_tag="ECOK1_0156"
                     /note="ABC-ATPase subunit  interface; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(178570..178572,178576..178578,178591..178593,
                     178753..178755,178759..178764,178771..178776,
                     178783..178788,178795..178797,178804..178809,
                     178813..178815,178846..178851,178858..178860,
                     179086..179088,179242..179244,179251..179256,
                     179263..179265,179272..179277,179284..179286)
                     /gene="fhuB"
                     /locus_tag="ECOK1_0156"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(178813..178815,178888..178890,179062..179064,
                     179074..179076,179206..179208,179233..179235)
                     /gene="fhuB"
                     /locus_tag="ECOK1_0156"
                     /note="putative PBP binding regions; other site"
                     /db_xref="CDD:119348"
     gene            complement(179339..180619)
                     /gene="hemL"
                     /locus_tag="ECOK1_0157"
                     /db_xref="GeneID:12688725"
     CDS             complement(179339..180619)
                     /gene="hemL"
                     /locus_tag="ECOK1_0157"
                     /EC_number="5.4.3.8"
                     /note="identified by similarity to SP:P23893; match to
                     protein family HMM PF00202; match to protein family HMM
                     TIGR00713"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde-2,1-aminomutase"
                     /protein_id="YP_006099412.1"
                     /db_xref="GI:386597906"
                     /db_xref="GeneID:12688725"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTEL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
                     FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVEPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEG
                     LREAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVY
                     LAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL"
     misc_feature    complement(179342..180619)
                     /gene="hemL"
                     /locus_tag="ECOK1_0157"
                     /note="glutamate-1-semialdehyde aminotransferase;
                     Provisional; Region: PRK00062"
                     /db_xref="CDD:234607"
     misc_feature    complement(179351..180601)
                     /gene="hemL"
                     /locus_tag="ECOK1_0157"
                     /note="Acetyl ornithine aminotransferase family. This
                     family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). The major
                     groups in this CD correspond to ornithine
                     aminotransferase, acetylornithine aminotransferase;
                     Region: OAT_like; cd00610"
                     /db_xref="CDD:99735"
     misc_feature    complement(order(179825..179827,179900..179905,
                     179909..179911,180008..180010,180185..180187,
                     180191..180196,180272..180280))
                     /gene="hemL"
                     /locus_tag="ECOK1_0157"
                     /note="inhibitor-cofactor binding pocket; inhibition site"
                     /db_xref="CDD:99735"
     misc_feature    complement(order(179825..179827,179900..179902,
                     179909..179911,180008..180010,180191..180196,
                     180272..180277))
                     /gene="hemL"
                     /locus_tag="ECOK1_0157"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99735"
     misc_feature    complement(179825..179827)
                     /gene="hemL"
                     /locus_tag="ECOK1_0157"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
     gene            180844..182265
                     /gene="clcA"
                     /locus_tag="ECOK1_0158"
                     /db_xref="GeneID:12688726"
     CDS             180844..182265
                     /gene="clcA"
                     /locus_tag="ECOK1_0158"
                     /note="identified by match to protein family HMM PF00654"
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter ClcA"
                     /protein_id="YP_006099413.1"
                     /db_xref="GI:386597907"
                     /db_xref="GeneID:12688726"
                     /translation="MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGT
                     LVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAP
                     EAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
                     MVLDVFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAV
                     FIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGM
                     QDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLV
                     FIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIA
                     GMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILA
                     RTLAKQEAEQLARSKAASARENT"
     misc_feature    180967..182193
                     /gene="clcA"
                     /locus_tag="ECOK1_0158"
                     /note="ClC chloride channel EriC.  This domain is found in
                     the EriC chloride transporters that mediate the extreme
                     acid resistance response in eubacteria and archaea. This
                     response allows bacteria to survive in the acidic
                     environments by decarboxylation-linked...; Region: EriC;
                     cd01031"
                     /db_xref="CDD:238504"
     misc_feature    order(181159..181173,181279..181293,181906..181920,
                     182176..182178)
                     /gene="clcA"
                     /locus_tag="ECOK1_0158"
                     /note="Cl- selectivity filter; other site"
                     /db_xref="CDD:238504"
     misc_feature    order(181162..181164,181168..181170,181285..181290,
                     181906..181914,182176..182178)
                     /gene="clcA"
                     /locus_tag="ECOK1_0158"
                     /note="Cl- binding residues [ion binding]; other site"
                     /db_xref="CDD:238504"
     misc_feature    181285..181287
                     /gene="clcA"
                     /locus_tag="ECOK1_0158"
                     /note="pore gating glutamate residue; other site"
                     /db_xref="CDD:238504"
     misc_feature    order(181423..181425,181450..181452,181489..181491,
                     181510..181512,182050..182052,182059..182061,
                     182083..182085,182119..182121,182140..182145,
                     182152..182154)
                     /gene="clcA"
                     /locus_tag="ECOK1_0158"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238504"
     misc_feature    181450..181452
                     /gene="clcA"
                     /locus_tag="ECOK1_0158"
                     /note="H+/Cl- coupling transport residue; other site"
                     /db_xref="CDD:238504"
     gene            182347..182691
                     /locus_tag="ECOK1_0159"
                     /db_xref="GeneID:12688727"
     CDS             182347..182691
                     /locus_tag="ECOK1_0159"
                     /note="identified by match to protein family HMM PF01521;
                     match to protein family HMM TIGR00049"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly accessory protein
                     YadR"
                     /protein_id="YP_006099414.1"
                     /db_xref="GI:386597908"
                     /db_xref="GeneID:12688727"
                     /translation="MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     misc_feature    182347..182688
                     /locus_tag="ECOK1_0159"
                     /note="iron-sulfur cluster insertion protein ErpA;
                     Provisional; Region: PRK13623"
                     /db_xref="CDD:184186"
     gene            complement(182738..183361)
                     /locus_tag="ECOK1_0160"
                     /db_xref="GeneID:12688728"
     CDS             complement(182738..183361)
                     /locus_tag="ECOK1_0160"
                     /note="identified by match to protein family HMM PF03458"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099415.1"
                     /db_xref="GI:386597909"
                     /db_xref="GeneID:12688728"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVRQPRRLPKWMLPVLDAVGLAVFV
                     GIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR"
     misc_feature    complement(182741..183361)
                     /locus_tag="ECOK1_0160"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10578"
                     /db_xref="CDD:182564"
     misc_feature    complement(183122..183355)
                     /locus_tag="ECOK1_0160"
                     /note="UPF0126 domain; Region: UPF0126; pfam03458"
                     /db_xref="CDD:251969"
     misc_feature    complement(182882..183094)
                     /locus_tag="ECOK1_0160"
                     /note="UPF0126 domain; Region: UPF0126; pfam03458"
                     /db_xref="CDD:251969"
     gene            complement(183399..184199)
                     /gene="btuF"
                     /locus_tag="ECOK1_0161"
                     /db_xref="GeneID:12688729"
     CDS             complement(183399..184199)
                     /gene="btuF"
                     /locus_tag="ECOK1_0161"
                     /note="identified by similarity to SP:P37028; match to
                     protein family HMM PF01497"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin ABC transporter periplasmic
                     cobalamin-binding protein"
                     /protein_id="YP_006099416.1"
                     /db_xref="GI:386597910"
                     /db_xref="GeneID:12688729"
                     /translation="MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITP
                     VGVSSYSDYPPQAQKIGQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGI
                     KVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
                     QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGP
                     DQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD"
     misc_feature    complement(183408..184127)
                     /gene="btuF"
                     /locus_tag="ECOK1_0161"
                     /note="ABC-type Fe3+-hydroxamate transport system,
                     periplasmic component [Inorganic ion transport and
                     metabolism]; Region: FepB; COG0614"
                     /db_xref="CDD:223687"
     misc_feature    complement(183420..184127)
                     /gene="btuF"
                     /locus_tag="ECOK1_0161"
                     /note="Cobalamin binding protein BtuF.  These proteins
                     have been shown to function as initial receptors in ABC
                     transport of vitamin B12 (cobalamin) in eubacterial and
                     some archaeal species.  They belong to the TroA
                     superfamily of helical backbone metal receptor...; Region:
                     BtuF; cd01144"
                     /db_xref="CDD:238564"
     misc_feature    complement(order(183612..183614,183696..183698,
                     183939..183941,183945..183947,184050..184052,
                     184104..184109))
                     /gene="btuF"
                     /locus_tag="ECOK1_0161"
                     /note="cobalamin binding residues [chemical binding];
                     other site"
                     /db_xref="CDD:238564"
     misc_feature    complement(order(183594..183596,183984..183986))
                     /gene="btuF"
                     /locus_tag="ECOK1_0161"
                     /note="putative BtuC binding residues; other site"
                     /db_xref="CDD:238564"
     misc_feature    complement(order(183837..183842,183849..183851,
                     183858..183863,183867..183869,183876..183878,
                     183888..183890,183906..183908,183915..183917,
                     183942..183944))
                     /gene="btuF"
                     /locus_tag="ECOK1_0161"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238564"
     gene            complement(184192..184890)
                     /gene="mtnN"
                     /locus_tag="ECOK1_0162"
                     /db_xref="GeneID:12688730"
     CDS             complement(184192..184890)
                     /gene="mtnN"
                     /locus_tag="ECOK1_0162"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /note="identified by similarity to SP:P0AF15; match to
                     protein family HMM PF01048; match to protein family HMM
                     TIGR01704"
                     /codon_start=1
                     /transl_table=11
                     /product="MTA/SAH nucleosidase"
                     /protein_id="YP_006099417.1"
                     /db_xref="GI:386597911"
                     /db_xref="GeneID:12688730"
                     /translation="MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     SLMVESLVQKLAHG"
     misc_feature    complement(184201..184890)
                     /gene="mtnN"
                     /locus_tag="ECOK1_0162"
                     /note="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase; Validated; Region: PRK05584"
                     /db_xref="CDD:180148"
     gene            184974..186491
                     /gene="dgt"
                     /locus_tag="ECOK1_0163"
                     /db_xref="GeneID:12688731"
     CDS             184974..186491
                     /gene="dgt"
                     /locus_tag="ECOK1_0163"
                     /EC_number="3.1.5.1"
                     /note="identified by similarity to SP:P15723; match to
                     protein family HMM PF01966; match to protein family HMM
                     TIGR01353"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyguanosinetriphosphate triphosphohydrolase"
                     /protein_id="YP_006099418.1"
                     /db_xref="GI:386597912"
                     /db_xref="GeneID:12688731"
                     /translation="MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDEL
                     TGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAAL
                     RLRDGEEPLNALRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFS
                     HPDVEQLELQGYRVISGLLEIYRPLLNLPLSDFTELVEKERVKRFPIETRLFHKLSTR
                     HRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ"
     misc_feature    184974..186485
                     /gene="dgt"
                     /locus_tag="ECOK1_0163"
                     /note="deoxyguanosinetriphosphate triphosphohydrolase;
                     Provisional; Region: dgt; PRK04926"
                     /db_xref="CDD:235320"
     misc_feature    185163..>185357
                     /gene="dgt"
                     /locus_tag="ECOK1_0163"
                     /note="Metal dependent phosphohydrolases with conserved
                     'HD' motif; Region: HDc; cd00077"
                     /db_xref="CDD:238032"
     misc_feature    order(185178..185180,185322..185327)
                     /gene="dgt"
                     /locus_tag="ECOK1_0163"
                     /note="Zn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238032"
     misc_feature    185325..185327
                     /gene="dgt"
                     /locus_tag="ECOK1_0163"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238032"
     misc_feature    186108..186470
                     /gene="dgt"
                     /locus_tag="ECOK1_0163"
                     /note="Phosphohydrolase-associated domain; Region:
                     HD_assoc; pfam13286"
                     /db_xref="CDD:257627"
     gene            186621..188045
                     /gene="degP"
                     /locus_tag="ECOK1_0164"
                     /db_xref="GeneID:12688732"
     CDS             186621..188045
                     /gene="degP"
                     /locus_tag="ECOK1_0164"
                     /EC_number="3.4.21.-"
                     /note="identified by similarity to SP:P09376; match to
                     protein family HMM PF00089; match to protein family HMM
                     PF00595; match to protein family HMM TIGR02037"
                     /codon_start=1
                     /transl_table=11
                     /product="protease Do"
                     /protein_id="YP_006099419.1"
                     /db_xref="GI:386597913"
                     /db_xref="GeneID:12688732"
                     /translation="MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPM
                     LEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGLGGN
                     GGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
                     DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNA
                     ENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNL
                     TSQMVEYGQVKRGELGIMGTELNSDLAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGD
                     VITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSST
                     IFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKV
                     LDSKPSVLALNIQRGDSTIYLLMQ"
     misc_feature    186624..188042
                     /gene="degP"
                     /locus_tag="ECOK1_0164"
                     /note="serine endoprotease; Provisional; Region: PRK10942"
                     /db_xref="CDD:236802"
     misc_feature    186960..187370
                     /gene="degP"
                     /locus_tag="ECOK1_0164"
                     /note="Trypsin-like peptidase domain; Region: Trypsin_2;
                     pfam13365"
                     /db_xref="CDD:257693"
     misc_feature    187491..187754
                     /gene="degP"
                     /locus_tag="ECOK1_0164"
                     /note="PDZ domain of trypsin-like serine proteases, such
                     as DegP/HtrA, which are oligomeric proteins involved in
                     heat-shock response, chaperone function, and apoptosis.
                     May be responsible for substrate recognition and/or
                     binding, as most PDZ domains bind...; Region:
                     PDZ_serine_protease; cd00987"
                     /db_xref="CDD:238487"
     misc_feature    order(187491..187499,187503..187505,187656..187661,
                     187668..187673)
                     /gene="degP"
                     /locus_tag="ECOK1_0164"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238487"
     misc_feature    187800..188033
                     /gene="degP"
                     /locus_tag="ECOK1_0164"
                     /note="PDZ domain of trypsin-like serine proteases, such
                     as DegP/HtrA, which are oligomeric proteins involved in
                     heat-shock response, chaperone function, and apoptosis.
                     May be responsible for substrate recognition and/or
                     binding, as most PDZ domains bind...; Region:
                     PDZ_serine_protease; cd00987"
                     /db_xref="CDD:238487"
     misc_feature    order(187800..187811,187815..187817,187947..187952,
                     187959..187964)
                     /gene="degP"
                     /locus_tag="ECOK1_0164"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238487"
     gene            188223..189353
                     /gene="cdaR"
                     /locus_tag="ECOK1_0165"
                     /db_xref="GeneID:12688733"
     CDS             188223..189353
                     /gene="cdaR"
                     /locus_tag="ECOK1_0165"
                     /note="identified by similarity to SP:P37047; match to
                     protein family HMM PF05651"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate diacid regulator"
                     /protein_id="YP_006099420.1"
                     /db_xref="GI:386597914"
                     /db_xref="GeneID:12688733"
                     /translation="MAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALL
                     VLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLRKYGELVCMT
                     AEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDLNQPRVVAIV
                     EVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNSFGRWDAEDH
                     RKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQRMPESRCYF
                     YQDLMLPVLLDSLRGDWQANELARPLARLKAMDNNGLLRRTLAAWFRHNVQPLATSKA
                     LFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER"
     misc_feature    188223..189350
                     /gene="cdaR"
                     /locus_tag="ECOK1_0165"
                     /note="carbohydrate diacid transcriptional activator CdaR;
                     Provisional; Region: PRK11477"
                     /db_xref="CDD:183155"
     misc_feature    188223..188615
                     /gene="cdaR"
                     /locus_tag="ECOK1_0165"
                     /note="Putative sugar diacid recognition; Region:
                     Diacid_rec; pfam05651"
                     /db_xref="CDD:147680"
     misc_feature    189171..189338
                     /gene="cdaR"
                     /locus_tag="ECOK1_0165"
                     /note="PucR C-terminal helix-turn-helix domain; Region:
                     HTH_30; pfam13556"
                     /db_xref="CDD:257873"
     gene            complement(189407..189793)
                     /locus_tag="ECOK1_0166"
                     /db_xref="GeneID:12688734"
     CDS             complement(189407..189793)
                     /locus_tag="ECOK1_0166"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099421.1"
                     /db_xref="GI:386597915"
                     /db_xref="GeneID:12688734"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAK
                     SVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILD
                     DLRHLESVVTNKISEIEADLEKLTRK"
     misc_feature    complement(189419..189793)
                     /locus_tag="ECOK1_0166"
                     /note="hypothetical protein; Provisional; Region:
                     PRK13677"
                     /db_xref="CDD:184234"
     gene            complement(190105..190929)
                     /gene="dapD"
                     /locus_tag="ECOK1_0167"
                     /db_xref="GeneID:12688735"
     CDS             complement(190105..190929)
                     /gene="dapD"
                     /locus_tag="ECOK1_0167"
                     /EC_number="2.3.1.117"
                     /note="identified by similarity to SP:P56220; match to
                     protein family HMM PF00132; match to protein family HMM
                     TIGR00965"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="YP_006099422.1"
                     /db_xref="GI:386597916"
                     /db_xref="GeneID:12688735"
                     /translation="MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFANYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRE
                     TGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     misc_feature    complement(190117..190929)
                     /gene="dapD"
                     /locus_tag="ECOK1_0167"
                     /note="2,3,4,5-tetrahydropyridine-2,6-carboxylate
                     N-succinyltransferase; Provisional; Region: dapD;
                     PRK11830"
                     /db_xref="CDD:236996"
     misc_feature    complement(190723..190926)
                     /gene="dapD"
                     /locus_tag="ECOK1_0167"
                     /note="Tetrahydrodipicolinate N-succinyltransferase
                     N-terminal; Region: THDPS_N_2; pfam14805"
                     /db_xref="CDD:258942"
     misc_feature    complement(190213..190626)
                     /gene="dapD"
                     /locus_tag="ECOK1_0167"
                     /note="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP)
                     N-succinyltransferase (also called THP
                     succinyltransferase): THDP N-succinyltransferase catalyzes
                     the conversion of tetrahydrodipicolinate and succinyl-CoA
                     to N-succinyltetrahydrodipicolinate and CoA; Region:
                     LbH_THP_succinylT; cd03350"
                     /db_xref="CDD:100041"
     misc_feature    complement(order(190213..190215,190219..190230,
                     190309..190311,190363..190365,190369..190371,
                     190447..190449,190495..190503,190549..190551,
                     190555..190557,190603..190608,190615..190620))
                     /gene="dapD"
                     /locus_tag="ECOK1_0167"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:100041"
     misc_feature    complement(order(190318..190323,190354..190356,
                     190369..190377,190414..190416,190423..190428,
                     190432..190434,190453..190455,190459..190461,
                     190486..190488,190507..190509,190543..190545,
                     190558..190560,190594..190596,190618..190620))
                     /gene="dapD"
                     /locus_tag="ECOK1_0167"
                     /note="active site"
                     /db_xref="CDD:100041"
     misc_feature    complement(order(190426..190428,190486..190488,
                     190507..190509,190543..190545,190558..190560,
                     190594..190596,190618..190620))
                     /gene="dapD"
                     /locus_tag="ECOK1_0167"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100041"
     misc_feature    complement(order(190318..190323,190354..190356,
                     190369..190377,190414..190416,190432..190434,
                     190450..190455))
                     /gene="dapD"
                     /locus_tag="ECOK1_0167"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:100041"
     gene            complement(190960..193632)
                     /gene="glnD"
                     /locus_tag="ECOK1_0168"
                     /db_xref="GeneID:12688736"
     CDS             complement(190960..193632)
                     /gene="glnD"
                     /locus_tag="ECOK1_0168"
                     /EC_number="2.7.7.59"
                     /note="identified by similarity to SP:P27249; match to
                     protein family HMM PF01842; match to protein family HMM
                     PF01909; match to protein family HMM PF01966; match to
                     protein family HMM PF08335; match to protein family HMM
                     TIGR01693"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-P-II uridylyltransferase"
                     /protein_id="YP_006099423.1"
                     /db_xref="GI:386597917"
                     /db_xref="GeneID:12688736"
                     /translation="MNTLPEQYANTALPTLSGQPQNPCAWPRDELTVGGIKAHIDTFQ
                     RWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHP
                     LSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
                     NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGI
                     YSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIF
                     IAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAW
                     HARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHF
                     TVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNELQQEVHQRLTEALNPNDKG"
     misc_feature    complement(190963..193614)
                     /gene="glnD"
                     /locus_tag="ECOK1_0168"
                     /note="PII uridylyl-transferase; Provisional; Region:
                     PRK05007"
                     /db_xref="CDD:235329"
     misc_feature    complement(193084..193482)
                     /gene="glnD"
                     /locus_tag="ECOK1_0168"
                     /note="Nucleotidyltransferase (NT) domain of Escherichia
                     coli adenylyltransferase (GlnE), Escherichia coli uridylyl
                     transferase (GlnD), and similar proteins; Region:
                     NT_GlnE_GlnD_like; cd05401"
                     /db_xref="CDD:143391"
     misc_feature    complement(order(193234..193236,193312..193314,
                     193318..193320))
                     /gene="glnD"
                     /locus_tag="ECOK1_0168"
                     /note="metal binding triad; metal-binding site"
                     /db_xref="CDD:143391"
     misc_feature    complement(192640..193059)
                     /gene="glnD"
                     /locus_tag="ECOK1_0168"
                     /note="GlnD PII-uridylyltransferase; Region:
                     GlnD_UR_UTase; pfam08335"
                     /db_xref="CDD:254738"
     misc_feature    complement(191779..192237)
                     /gene="glnD"
                     /locus_tag="ECOK1_0168"
                     /note="Metal dependent phosphohydrolases with conserved
                     'HD' motif; Region: HDc; cd00077"
                     /db_xref="CDD:238032"
     misc_feature    complement(order(191842..191844,192088..192093,
                     192220..192222))
                     /gene="glnD"
                     /locus_tag="ECOK1_0168"
                     /note="Zn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238032"
     misc_feature    complement(192088..192090)
                     /gene="glnD"
                     /locus_tag="ECOK1_0168"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238032"
     misc_feature    complement(191299..191514)
                     /gene="glnD"
                     /locus_tag="ECOK1_0168"
                     /note="ACT domain family, ACT_UUR-like_1, includes the
                     first of two C-terminal ACT domains of the bacterial
                     signal-transducing uridylyltransferase /uridylyl-removing
                     (UUR) enzyme, GlnD and related domains; Region:
                     ACT_UUR-like_1; cd04900"
                     /db_xref="CDD:153172"
     misc_feature    complement(190981..191184)
                     /gene="glnD"
                     /locus_tag="ECOK1_0168"
                     /note="C-terminal ACT domains of the bacterial
                     signal-transducing uridylyltransferase /uridylyl-removing
                     (UUR) enzyme, GlnD and related domains; Region:
                     ACT_ACR-UUR-like_2; cd04899"
                     /db_xref="CDD:153171"
     gene            complement(193694..194488)
                     /gene="map"
                     /locus_tag="ECOK1_0169"
                     /db_xref="GeneID:12688737"
     CDS             complement(193694..194488)
                     /gene="map"
                     /locus_tag="ECOK1_0169"
                     /EC_number="3.4.11.18"
                     /note="identified by match to protein family HMM PF00557;
                     match to protein family HMM TIGR00500"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine aminopeptidase"
                     /protein_id="YP_006099424.1"
                     /db_xref="GI:386597918"
                     /db_xref="GeneID:12688737"
                     /translation="MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRI
                     CNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIK
                     DGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE"
     misc_feature    complement(193739..194458)
                     /gene="map"
                     /locus_tag="ECOK1_0169"
                     /note="Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also
                     known as methionyl aminopeptidase and Peptidase M.
                     Catalyzes release of N-terminal amino acids,
                     preferentially methionine, from peptides and arylamides;
                     Region: MetAP1; cd01086"
                     /db_xref="CDD:238519"
     misc_feature    complement(order(193784..193786,193877..193879,
                     193976..193978,194165..194167,194198..194200,
                     194252..194254))
                     /gene="map"
                     /locus_tag="ECOK1_0169"
                     /note="active site"
                     /db_xref="CDD:238519"
     gene            194856..195581
                     /gene="rpsB"
                     /locus_tag="ECOK1_0170"
                     /db_xref="GeneID:12688738"
     CDS             194856..195581
                     /gene="rpsB"
                     /locus_tag="ECOK1_0170"
                     /note="identified by match to protein family HMM PF00318;
                     match to protein family HMM TIGR01011"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="YP_006099425.1"
                     /db_xref="GI:386597919"
                     /db_xref="GeneID:12688738"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     misc_feature    194880..195524
                     /gene="rpsB"
                     /locus_tag="ECOK1_0170"
                     /note="Ribosomal protein S2 (RPS2), involved in formation
                     of the translation initiation complex, where it might
                     contact the messenger RNA and several components of the
                     ribosome. It has been shown that in Escherichia coli RPS2
                     is essential for the binding of...; Region: RPS2; cd01425"
                     /db_xref="CDD:100106"
     misc_feature    order(194928..194933,194958..194966,195138..195140,
                     195144..195152,195159..195164,195378..195380,
                     195387..195389)
                     /gene="rpsB"
                     /locus_tag="ECOK1_0170"
                     /note="rRNA interaction site [nucleotide binding]; other
                     site"
                     /db_xref="CDD:100106"
     misc_feature    order(195384..195389,195393..195395,195435..195446)
                     /gene="rpsB"
                     /locus_tag="ECOK1_0170"
                     /note="S8 interaction site; other site"
                     /db_xref="CDD:100106"
     misc_feature    195489..195506
                     /gene="rpsB"
                     /locus_tag="ECOK1_0170"
                     /note="putative laminin-1 binding site; other site"
                     /db_xref="CDD:100106"
     gene            195716..196567
                     /gene="tsf"
                     /locus_tag="ECOK1_0171"
                     /db_xref="GeneID:12688739"
     CDS             195716..196567
                     /gene="tsf"
                     /locus_tag="ECOK1_0171"
                     /note="identified by match to protein family HMM PF00627;
                     match to protein family HMM PF00889; match to protein
                     family HMM TIGR00116"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="YP_006099426.1"
                     /db_xref="GI:386597920"
                     /db_xref="GeneID:12688739"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     misc_feature    195716..196558
                     /gene="tsf"
                     /locus_tag="ECOK1_0171"
                     /note="elongation factor Ts; Provisional; Region: tsf;
                     PRK09377"
                     /db_xref="CDD:236491"
     misc_feature    195734..195844
                     /gene="tsf"
                     /locus_tag="ECOK1_0171"
                     /note="UBA domain found in elongation factor Ts (EF-Ts)
                     from bacteria, chloroplasts and mitochondria of
                     eukaryotes; Region: UBA_EF-Ts; cd14275"
                     /db_xref="CDD:270461"
     misc_feature    order(195740..195745,195752..195757,195773..195778,
                     195785..195787)
                     /gene="tsf"
                     /locus_tag="ECOK1_0171"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:270461"
     misc_feature    <196028..>196153
                     /gene="tsf"
                     /locus_tag="ECOK1_0171"
                     /note="Bacterial virulence factor haemolysin; Region:
                     SMP_2; cl11479"
                     /db_xref="CDD:271719"
     gene            196714..197439
                     /gene="pyrH"
                     /locus_tag="ECOK1_0172"
                     /db_xref="GeneID:12688740"
     CDS             196714..197439
                     /gene="pyrH"
                     /locus_tag="ECOK1_0172"
                     /EC_number="2.7.4.22"
                     /note="identified by similarity to SP:P0A7E9; match to
                     protein family HMM PF00696; match to protein family HMM
                     TIGR02075"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="YP_006099427.1"
                     /db_xref="GI:386597921"
                     /db_xref="GeneID:12688740"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     misc_feature    196741..197433
                     /gene="pyrH"
                     /locus_tag="ECOK1_0172"
                     /note="UMP kinase (UMPK)-Ec, the microbial/chloroplast
                     uridine monophosphate kinase (uridylate kinase) enzyme
                     that catalyzes UMP phosphorylation and plays a key role in
                     pyrimidine nucleotide biosynthesis; regulation of this
                     process is via feed-back control and...; Region:
                     AAK_UMPK-PyrH-Ec; cd04254"
                     /db_xref="CDD:239787"
     misc_feature    order(196756..196758,196765..196770,196879..196887,
                     197146..197151,197206..197211,197218..197220,
                     197224..197226,197230..197235)
                     /gene="pyrH"
                     /locus_tag="ECOK1_0172"
                     /note="putative nucleotide binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:239787"
     misc_feature    order(196879..196887,196897..196902,196942..196944,
                     196951..196956,197125..197127,197131..197136,
                     197140..197148)
                     /gene="pyrH"
                     /locus_tag="ECOK1_0172"
                     /note="uridine monophosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:239787"
     misc_feature    order(196918..196923,196945..196950,196969..196971,
                     196990..196992,197020..197022,197062..197064,
                     197074..197076,197083..197085,197101..197103,
                     197125..197127,197131..197139,197164..197166,
                     197173..197178,197344..197346)
                     /gene="pyrH"
                     /locus_tag="ECOK1_0172"
                     /note="homohexameric interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239787"
     gene            197589..198146
                     /gene="frr"
                     /locus_tag="ECOK1_0173"
                     /db_xref="GeneID:12688741"
     CDS             197589..198146
                     /gene="frr"
                     /locus_tag="ECOK1_0173"
                     /note="identified by match to protein family HMM PF01765;
                     match to protein family HMM TIGR00496"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="YP_006099428.1"
                     /db_xref="GI:386597922"
                     /db_xref="GeneID:12688741"
                     /translation="MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
                     QKLTDAAIKKIEAALADKEAELMQF"
     misc_feature    197601..198137
                     /gene="frr"
                     /locus_tag="ECOK1_0173"
                     /note="Ribosome recycling factor (RRF). Ribosome recycling
                     factor dissociates the posttermination complex, composed
                     of the ribosome, deacylated tRNA, and mRNA, after
                     termination of translation.  Thus ribosomes are 'recycled'
                     and ready for another...; Region: RRF; cd00520"
                     /db_xref="CDD:238288"
     misc_feature    order(197673..197684,197892..197903)
                     /gene="frr"
                     /locus_tag="ECOK1_0173"
                     /note="hinge region; other site"
                     /db_xref="CDD:238288"
     gene            198238..199434
                     /gene="dxr"
                     /locus_tag="ECOK1_0174"
                     /db_xref="GeneID:12688742"
     CDS             198238..199434
                     /gene="dxr"
                     /locus_tag="ECOK1_0174"
                     /EC_number="1.1.1.267"
                     /note="identified by similarity to SP:P45568; match to
                     protein family HMM PF02670; match to protein family HMM
                     PF08436; match to protein family HMM TIGR00243"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose 5-phosphate reductoisomerase"
                     /protein_id="YP_006099429.1"
                     /db_xref="GI:386597923"
                     /db_xref="GeneID:12688742"
                     /translation="MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVARMVE
                     QCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL
                     PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDANAREVARKE
                     VMRLAS"
     misc_feature    198238..199431
                     /gene="dxr"
                     /locus_tag="ECOK1_0174"
                     /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase;
                     Provisional; Region: PRK05447"
                     /db_xref="CDD:235472"
     misc_feature    198247..198633
                     /gene="dxr"
                     /locus_tag="ECOK1_0174"
                     /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase;
                     Region: DXP_reductoisom; pfam02670"
                     /db_xref="CDD:251461"
     misc_feature    198673..198954
                     /gene="dxr"
                     /locus_tag="ECOK1_0174"
                     /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase
                     C-terminal; Region: DXP_redisom_C; pfam08436"
                     /db_xref="CDD:254800"
     misc_feature    199048..199404
                     /gene="dxr"
                     /locus_tag="ECOK1_0174"
                     /note="DXP reductoisomerase C-terminal domain; Region:
                     DXPR_C; pfam13288"
                     /db_xref="CDD:257629"
     gene            199623..200381
                     /gene="uppS"
                     /locus_tag="ECOK1_0175"
                     /db_xref="GeneID:12688743"
     CDS             199623..200381
                     /gene="uppS"
                     /locus_tag="ECOK1_0175"
                     /EC_number="2.5.1.31"
                     /note="identified by match to protein family HMM PF01255;
                     match to protein family HMM TIGR00055"
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="YP_006099430.1"
                     /db_xref="GI:386597924"
                     /db_xref="GeneID:12688743"
                     /translation="MLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
                     GAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
                     NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEK
                     VQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
                     LWPDFDEQDFEGALNAFANRERRFGGTEPGDETA"
     misc_feature    199677..200333
                     /gene="uppS"
                     /locus_tag="ECOK1_0175"
                     /note="Cis (Z)-Isoprenyl Diphosphate Synthases; Region:
                     Cis_IPPS; cd00475"
                     /db_xref="CDD:259850"
     misc_feature    order(199692..199709,199734..199736,199746..199748,
                     199758..199760,199767..199769,199824..199826,
                     199848..199850,199860..199862,199881..199886,
                     199893..199895,200040..200042,200199..200201,
                     200217..200219,200223..200225)
                     /gene="uppS"
                     /locus_tag="ECOK1_0175"
                     /note="active site"
                     /db_xref="CDD:259850"
     misc_feature    order(200061..200066,200070..200075,200082..200087,
                     200133..200141,200148..200150,200181..200183,
                     200214..200228,200235..200243,200247..200261,
                     200265..200267)
                     /gene="uppS"
                     /locus_tag="ECOK1_0175"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:259850"
     gene            200394..201251
                     /gene="cdsA"
                     /locus_tag="ECOK1_0176"
                     /db_xref="GeneID:12688744"
     CDS             200394..201251
                     /gene="cdsA"
                     /locus_tag="ECOK1_0176"
                     /EC_number="2.7.7.41"
                     /note="identified by match to protein family HMM PF01148"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="YP_006099431.1"
                     /db_xref="GI:386597925"
                     /db_xref="GeneID:12688744"
                     /translation="MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWG
                     QLSGFTTRSQRVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLL
                     VLFYPGSAAIWRNSKTLRIIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
                     VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLVTAAVISWGYGMWVNLDVAPV
                     TLLICSIVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
                     LLLLVFRTL"
     misc_feature    200394..201248
                     /gene="cdsA"
                     /locus_tag="ECOK1_0176"
                     /note="CDP-diglyceride synthase; Provisional; Region:
                     cdsA; PRK11624"
                     /db_xref="CDD:183240"
     gene            201263..202615
                     /gene="rseP"
                     /locus_tag="ECOK1_0177"
                     /db_xref="GeneID:12688745"
     CDS             201263..202615
                     /gene="rseP"
                     /locus_tag="ECOK1_0177"
                     /EC_number="3.4.24.-"
                     /note="identified by similarity to SP:P37764; match to
                     protein family HMM PF00595; match to protein family HMM
                     PF02163; match to protein family HMM TIGR00054"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="YP_006099432.1"
                     /db_xref="GI:386597926"
                     /db_xref="GeneID:12688745"
                     /translation="MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
                     DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPR
                     GPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEI
                     ERQGSPLSLTLIPESKPGKGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKT
                     WQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
                     "
     misc_feature    201266..202612
                     /gene="rseP"
                     /locus_tag="ECOK1_0177"
                     /note="zinc metallopeptidase RseP; Provisional; Region:
                     PRK10779"
                     /db_xref="CDD:182723"
     misc_feature    201284..>201622
                     /gene="rseP"
                     /locus_tag="ECOK1_0177"
                     /note="RseP-like Site-2 proteases (S2P), zinc
                     metalloproteases (MEROPS family M50A), cleave
                     transmembrane domains of substrate proteins, regulating
                     intramembrane proteolysis (RIP) of diverse signal
                     transduction mechanisms. In Escherichia coli, the S2P
                     homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163"
                     /db_xref="CDD:100084"
     misc_feature    order(201326..201331,201338..201340)
                     /gene="rseP"
                     /locus_tag="ECOK1_0177"
                     /note="active site"
                     /db_xref="CDD:100084"
     misc_feature    201608..201847
                     /gene="rseP"
                     /locus_tag="ECOK1_0177"
                     /note="PDZ domain of bacterial and plant zinc
                     metalloprotases, presumably membrane-associated or
                     integral membrane proteases, which may be involved in
                     signalling and regulatory mechanisms. May be responsible
                     for substrate recognition and/or binding, as most PDZ...;
                     Region: PDZ_metalloprotease; cd00989"
                     /db_xref="CDD:238489"
     misc_feature    order(201611..201622,201626..201628,201755..201760,
                     201767..201772)
                     /gene="rseP"
                     /locus_tag="ECOK1_0177"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238489"
     misc_feature    201893..202129
                     /gene="rseP"
                     /locus_tag="ECOK1_0177"
                     /note="PDZ domain of bacterial and plant zinc
                     metalloprotases, presumably membrane-associated or
                     integral membrane proteases, which may be involved in
                     signalling and regulatory mechanisms. May be responsible
                     for substrate recognition and/or binding, as most PDZ...;
                     Region: PDZ_metalloprotease; cd00989"
                     /db_xref="CDD:238489"
     misc_feature    order(201896..201907,201911..201913,202040..202045,
                     202052..202057)
                     /gene="rseP"
                     /locus_tag="ECOK1_0177"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238489"
     misc_feature    <202400..202609
                     /gene="rseP"
                     /locus_tag="ECOK1_0177"
                     /note="Site-2 protease (S2P) class of zinc
                     metalloproteases (MEROPS family M50) cleaves transmembrane
                     domains of substrate proteins, regulating intramembrane
                     proteolysis (RIP) of diverse signal transduction
                     mechanisms. Members of this family use proteolytic...;
                     Region: S2P-M50; cl10020"
                     /db_xref="CDD:245232"
     misc_feature    202442..202453
                     /gene="rseP"
                     /locus_tag="ECOK1_0177"
                     /note="putative substrate binding region [chemical
                     binding]; other site"
                     /db_xref="CDD:100078"
     gene            202645..205077
                     /gene="yaeT"
                     /locus_tag="ECOK1_0178"
                     /db_xref="GeneID:12688746"
     CDS             202645..205077
                     /gene="yaeT"
                     /locus_tag="ECOK1_0178"
                     /note="identified by match to protein family HMM PF01103;
                     match to protein family HMM PF07244; match to protein
                     family HMM TIGR03303"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly complex, YaeT
                     protein"
                     /protein_id="YP_006099433.1"
                     /db_xref="GI:386597927"
                     /db_xref="GeneID:12688746"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGN
                     LAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKS
                     YGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFK
                     TDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDD
                     HKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNY
                     DPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWD
                     MGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDK
                     AEQFQFNIGKTW"
     misc_feature    202645..205074
                     /gene="yaeT"
                     /locus_tag="ECOK1_0178"
                     /note="outer membrane protein assembly factor YaeT;
                     Provisional; Region: PRK11067"
                     /db_xref="CDD:236834"
     misc_feature    202714..202917
                     /gene="yaeT"
                     /locus_tag="ECOK1_0178"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:254121"
     misc_feature    202918..203160
                     /gene="yaeT"
                     /locus_tag="ECOK1_0178"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:254121"
     misc_feature    203167..203433
                     /gene="yaeT"
                     /locus_tag="ECOK1_0178"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:254121"
     misc_feature    203440..203676
                     /gene="yaeT"
                     /locus_tag="ECOK1_0178"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:254121"
     misc_feature    203683..203907
                     /gene="yaeT"
                     /locus_tag="ECOK1_0178"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:254121"
     misc_feature    203986..205074
                     /gene="yaeT"
                     /locus_tag="ECOK1_0178"
                     /note="Surface antigen; Region: Bac_surface_Ag; pfam01103"
                     /db_xref="CDD:250364"
     gene            205199..205684
                     /gene="skp"
                     /locus_tag="ECOK1_0179"
                     /db_xref="GeneID:12688747"
     CDS             205199..205684
                     /gene="skp"
                     /locus_tag="ECOK1_0179"
                     /note="identified by similarity to SP:P31519; match to
                     protein family HMM PF03938"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone protein Skp"
                     /protein_id="YP_006099434.1"
                     /db_xref="GI:386597928"
                     /db_xref="GeneID:12688747"
                     /translation="MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSN
                     TLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFE
                     QDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQV
                     K"
     misc_feature    205199..205681
                     /gene="skp"
                     /locus_tag="ECOK1_0179"
                     /note="periplasmic chaperone; Provisional; Region:
                     PRK10780"
                     /db_xref="CDD:182724"
     gene            205688..206713
                     /gene="lpxD"
                     /locus_tag="ECOK1_0180"
                     /db_xref="GeneID:12688748"
     CDS             205688..206713
                     /gene="lpxD"
                     /locus_tag="ECOK1_0180"
                     /EC_number="2.3.1.-"
                     /note="identified by match to protein family HMM PF00132;
                     match to protein family HMM PF04613; match to protein
                     family HMM TIGR01853"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-[3-hydroxymyristoyl] glucosamine
                     N-acyltransferase"
                     /protein_id="YP_006099435.1"
                     /db_xref="GI:386597929"
                     /db_xref="GeneID:12688748"
                     /translation="MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPKPAQNIAP
                     SAVIDETAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTI
                     YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRG
                     ALDDTVIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLE
                     RKVNQQD"
     misc_feature    205691..206707
                     /gene="lpxD"
                     /locus_tag="ECOK1_0180"
                     /note="UDP-3-O-[3-hydroxymyristoyl] glucosamine
                     N-acyltransferase; Provisional; Region: lpxD; PRK00892"
                     /db_xref="CDD:234858"
     misc_feature    205748..205957
                     /gene="lpxD"
                     /locus_tag="ECOK1_0180"
                     /note="UDP-3-O-[3-hydroxymyristoyl] glucosamine
                     N-acyltransferase, LpxD; Region: LpxD; pfam04613"
                     /db_xref="CDD:252703"
     misc_feature    206012..206629
                     /gene="lpxD"
                     /locus_tag="ECOK1_0180"
                     /note="UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD):
                     The enzyme catalyzes the transfer of 3-hydroxymyristic
                     acid or 3-hydroxy-arachidic acid, depending on the
                     organism, from the acyl carrier protein (ACP) to
                     UDP-3-O-acyl-glucosamine to produce UDP-2; Region:
                     LbH_LpxD; cd03352"
                     /db_xref="CDD:100043"
     misc_feature    order(206048..206050,206060..206065,206117..206119,
                     206156..206158,206162..206164,206168..206170,
                     206204..206206,206210..206212,206228..206230,
                     206234..206236,206267..206275,206309..206311,
                     206321..206323,206327..206329,206333..206335,
                     206342..206350,206375..206377,206381..206389,
                     206393..206395,206405..206407,206423..206425,
                     206429..206431,206441..206449,206477..206479,
                     206495..206503,206513..206515,206549..206557,
                     206609..206611,206621..206623)
                     /gene="lpxD"
                     /locus_tag="ECOK1_0180"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:100043"
     misc_feature    order(206234..206242,206381..206383,206393..206395,
                     206402..206407,206435..206440,206453..206461,
                     206510..206515,206546..206548)
                     /gene="lpxD"
                     /locus_tag="ECOK1_0180"
                     /note="active site"
                     /db_xref="CDD:100043"
     misc_feature    order(206234..206242,206402..206407,206456..206461,
                     206510..206515)
                     /gene="lpxD"
                     /locus_tag="ECOK1_0180"
                     /note="UDP-GlcNAc binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100043"
     misc_feature    order(206381..206383,206393..206395,206435..206440,
                     206453..206455,206546..206548)
                     /gene="lpxD"
                     /locus_tag="ECOK1_0180"
                     /note="lipid binding site [chemical binding];
                     lipid-binding site"
                     /db_xref="CDD:100043"
     gene            206818..207273
                     /gene="fabZ"
                     /locus_tag="ECOK1_0181"
                     /db_xref="GeneID:12688749"
     CDS             206818..207273
                     /gene="fabZ"
                     /locus_tag="ECOK1_0181"
                     /EC_number="4.2.1.-"
                     /note="identified by match to protein family HMM PF07977;
                     match to protein family HMM TIGR01750"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hydroxyacyl-(acyl-carrier-protein)
                     dehydratase FabZ"
                     /protein_id="YP_006099436.1"
                     /db_xref="GI:386597930"
                     /db_xref="GeneID:12688749"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     misc_feature    206866..207255
                     /gene="fabZ"
                     /locus_tag="ECOK1_0181"
                     /note="FabZ is a 17kD beta-hydroxyacyl-acyl carrier
                     protein (ACP) dehydratase that primarily catalyzes the
                     dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP,
                     the third step in the elongation phase of the bacterial/
                     plastid, type II, fatty-acid...; Region: FabZ; cd01288"
                     /db_xref="CDD:238615"
     gene            207277..208065
                     /gene="lpxA"
                     /locus_tag="ECOK1_0182"
                     /db_xref="GeneID:12688750"
     CDS             207277..208065
                     /gene="lpxA"
                     /locus_tag="ECOK1_0182"
                     /EC_number="2.3.1.129"
                     /note="identified by match to protein family HMM PF00132;
                     match to protein family HMM TIGR01852"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="YP_006099437.1"
                     /db_xref="GI:386597931"
                     /db_xref="GeneID:12688750"
                     /translation="MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL
                     KSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNA
                     YKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR"
     misc_feature    207286..208062
                     /gene="lpxA"
                     /locus_tag="ECOK1_0182"
                     /note="UDP-N-acetylglucosamine acyltransferase;
                     Provisional; Region: PRK05289"
                     /db_xref="CDD:235390"
     misc_feature    207298..208056
                     /gene="lpxA"
                     /locus_tag="ECOK1_0182"
                     /note="UDP-N-acetylglucosamine O-acyltransferase
                     (UDP-GlcNAc acyltransferase): Proteins in this family
                     catalyze the transfer of (R)-3-hydroxymyristic acid from
                     its acyl carrier protein thioester to UDP-GlcNAc. It is
                     the first enzyme in the lipid A biosynthetic...; Region:
                     LbH_UDP-GlcNAc_AT; cd03351"
                     /db_xref="CDD:100042"
     misc_feature    order(207493..207495,207502..207504,207571..207573,
                     207640..207642,207649..207651,207706..207708,
                     207754..207759,207793..207795,207868..207870,
                     207886..207891)
                     /gene="lpxA"
                     /locus_tag="ECOK1_0182"
                     /note="active site"
                     /db_xref="CDD:100042"
     gene            208065..209213
                     /gene="lpxB"
                     /locus_tag="ECOK1_0183"
                     /db_xref="GeneID:12688751"
     CDS             208065..209213
                     /gene="lpxB"
                     /locus_tag="ECOK1_0183"
                     /EC_number="2.4.1.182"
                     /note="identified by match to protein family HMM PF02684;
                     match to protein family HMM TIGR00215"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="YP_006099438.1"
                     /db_xref="GI:386597932"
                     /db_xref="GeneID:12688751"
                     /translation="MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDF
                     NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVP
                     CRFIGHTMADAMPLDPDKNGARDVLGIPYDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQTYPDLEIVVPLVNAKRREQFERIKAAVAPDLSVHLLDGMGREAMVASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEP
                     QKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ"
     misc_feature    208080..209210
                     /gene="lpxB"
                     /locus_tag="ECOK1_0183"
                     /note="lipid-A-disaccharide synthase; Reviewed; Region:
                     lpxB; PRK00025"
                     /db_xref="CDD:234580"
     misc_feature    208086..209057
                     /gene="lpxB"
                     /locus_tag="ECOK1_0183"
                     /note="ipid-A-disaccharide synthase; Provisional; Region:
                     PRK14089"
                     /db_xref="CDD:237606"
     gene            209210..209806
                     /gene="rnhB"
                     /locus_tag="ECOK1_0184"
                     /db_xref="GeneID:12688752"
     CDS             209210..209806
                     /gene="rnhB"
                     /locus_tag="ECOK1_0184"
                     /EC_number="3.1.26.4"
                     /note="identified by match to protein family HMM PF01351"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="YP_006099439.1"
                     /db_xref="GI:386597933"
                     /db_xref="GeneID:12688752"
                     /translation="MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLN
                     DSKKLSEKRRLVLCEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPKLPMPSMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
                     QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS"
     misc_feature    209246..209776
                     /gene="rnhB"
                     /locus_tag="ECOK1_0184"
                     /note="Bacterial Ribonuclease HII-like; Region:
                     RNase_HII_bacteria_HII_like; cd07182"
                     /db_xref="CDD:260003"
     misc_feature    order(209255..209272,209348..209350,209453..209461,
                     209531..209539,209576..209581,209585..209587,
                     209627..209629,209690..209698,209702..209710,
                     209768..209776)
                     /gene="rnhB"
                     /locus_tag="ECOK1_0184"
                     /note="RNA/DNA hybrid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:260003"
     misc_feature    order(209255..209260,209531..209533,209585..209587)
                     /gene="rnhB"
                     /locus_tag="ECOK1_0184"
                     /note="active site"
                     /db_xref="CDD:260003"
     gene            209843..213325
                     /gene="dnaE"
                     /locus_tag="ECOK1_0185"
                     /db_xref="GeneID:12688753"
     CDS             209843..213325
                     /gene="dnaE"
                     /locus_tag="ECOK1_0185"
                     /EC_number="2.7.7.7"
                     /note="identified by similarity to SP:P10443; match to
                     protein family HMM PF01336; match to protein family HMM
                     PF02811; match to protein family HMM PF07733; match to
                     protein family HMM TIGR00594"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="YP_006099440.1"
                     /db_xref="GI:386597934"
                     /db_xref="GeneID:12688753"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGTAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
                     HFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERLKRRPEYDERLDTELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     misc_feature    209855..213295
                     /gene="dnaE"
                     /locus_tag="ECOK1_0185"
                     /note="DNA polymerase III subunit alpha; Validated;
                     Region: dnaE; PRK05673"
                     /db_xref="CDD:235554"
     misc_feature    209855..210685
                     /gene="dnaE"
                     /locus_tag="ECOK1_0185"
                     /note="Polymerase and Histidinol Phosphatase domain of
                     alpha-subunit of bacterial polymerase III DnaE1; Region:
                     PHP_PolIIIA_DnaE1; cd07433"
                     /db_xref="CDD:213988"
     misc_feature    order(209870..209872,209876..209878,209897..209899,
                     209972..209974,210047..210049,210443..210445,
                     210449..210451)
                     /gene="dnaE"
                     /locus_tag="ECOK1_0185"
                     /note="putative active site [active]"
                     /db_xref="CDD:213988"
     misc_feature    order(210014..210016,210026..210034,210644..210646)
                     /gene="dnaE"
                     /locus_tag="ECOK1_0185"
                     /note="putative PHP Thumb interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:213988"
     misc_feature    210710..212047
                     /gene="dnaE"
                     /locus_tag="ECOK1_0185"
                     /note="Bacterial DNA polymerase III alpha subunit; Region:
                     DNA_pol3_alpha; pfam07733"
                     /db_xref="CDD:254393"
     misc_feature    212264..212536
                     /gene="dnaE"
                     /locus_tag="ECOK1_0185"
                     /note="Helix-hairpin-helix motif; Region: HHH_6;
                     pfam14579"
                     /db_xref="CDD:258717"
     misc_feature    212825..213082
                     /gene="dnaE"
                     /locus_tag="ECOK1_0185"
                     /note="DnaE_OBF: A subfamily of OB folds corresponding to
                     the C-terminal OB-fold nucleic acid binding domain of
                     Thermus aquaticus and Escherichia coli type C replicative
                     DNA polymerase III alpha subunit (DnaE). The DNA
                     polymerase holoenzyme of E. coli contains...; Region:
                     DnaE_OBF; cd04485"
                     /db_xref="CDD:239931"
     misc_feature    order(212825..212827,212981..212983,212987..212989,
                     212993..212995,213053..213055)
                     /gene="dnaE"
                     /locus_tag="ECOK1_0185"
                     /note="generic binding surface II; other site"
                     /db_xref="CDD:239931"
     misc_feature    order(212840..212848,212888..212899,212903..212905,
                     212921..212929,212933..212935,212978..212980,
                     212999..213007,213032..213040)
                     /gene="dnaE"
                     /locus_tag="ECOK1_0185"
                     /note="generic binding surface I; other site"
                     /db_xref="CDD:239931"
     gene            213338..214297
                     /gene="accA"
                     /locus_tag="ECOK1_0186"
                     /db_xref="GeneID:12688754"
     CDS             213338..214297
                     /gene="accA"
                     /locus_tag="ECOK1_0186"
                     /EC_number="6.4.1.2"
                     /note="identified by match to protein family HMM PF03255;
                     match to protein family HMM TIGR00513"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyl transferase
                     subunit alpha"
                     /protein_id="YP_006099441.1"
                     /db_xref="GI:386597935"
                     /db_xref="GeneID:12688754"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLTDLADLDVLSTEDLKNRRYQRLMSYGYA"
     misc_feature    213338..214291
                     /gene="accA"
                     /locus_tag="ECOK1_0186"
                     /note="acetyl-CoA carboxylase carboxyltransferase subunit
                     alpha; Validated; Region: PRK05724"
                     /db_xref="CDD:235580"
     gene            214395..216536
                     /gene="ldcC"
                     /locus_tag="ECOK1_0187"
                     /note="lysine decarboxylase, constitutive, authentic point
                     mutation; this gene contains a premature stop which is not
                     the result of sequencing error; identified by similarity
                     to SP:P52095; match to protein family HMM PF01276; match
                     to protein family HMM PF03709; match to protein family HMM
                     PF03711"
                     /pseudo
                     /db_xref="GeneID:12688755"
     gene            216593..216982
                     /locus_tag="ECOK1_0188"
                     /db_xref="GeneID:12688756"
     CDS             216593..216982
                     /locus_tag="ECOK1_0188"
                     /note="identified by match to protein family HMM PF00903"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylase"
                     /protein_id="YP_006099442.1"
                     /db_xref="GI:386597936"
                     /db_xref="GeneID:12688756"
                     /translation="MLGLKQVHHIAIIATDYAMSKAFYCDILGFTLQSEVYREARDSW
                     KGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCEA
                     IRVDPYTQKRFTFFNDPDGLPLELYEQ"
     misc_feature    216602..216976
                     /locus_tag="ECOK1_0188"
                     /note="This conserved domain belongs to a superfamily
                     including the bleomycin resistance protein, glyoxalase I,
                     and type I ring-cleaving dioxygenases; Region:
                     Glo_EDI_BRP_like_1; cd08352"
                     /db_xref="CDD:211358"
     misc_feature    order(216617..216619,216824..216826,216965..216967)
                     /locus_tag="ECOK1_0188"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:211358"
     gene            217047..218345
                     /gene="tilS"
                     /locus_tag="ECOK1_0189"
                     /db_xref="GeneID:12688757"
     CDS             217047..218345
                     /gene="tilS"
                     /locus_tag="ECOK1_0189"
                     /EC_number="6.3.4.-"
                     /note="identified by similarity to SP:P52097; match to
                     protein family HMM PF01171; match to protein family HMM
                     PF09179; match to protein family HMM TIGR02432; match to
                     protein family HMM TIGR02433"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(Ile)-lysidine synthase"
                     /protein_id="YP_006099443.1"
                     /db_xref="GI:386597937"
                     /db_xref="GeneID:12688757"
                     /translation="MTLTLNRQLLSSRQILVAFSGGLDSTVLLHQLVQWRTENPGVTL
                     RAIHVHHGLSANADAWVKHCENICQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFA
                     RTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTQLIRPLLARTR
                     GELVQWALAHGLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAE
                     QESLLDELLADDLAHCQTPQGTLQIAPMLAMSDARRAAIIRRWLAGQNAPMPSRDALV
                     RIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKFVTGQSETIVPWQTWLQPLELPA
                     GLGSVQLTAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRD
                     TTPLLFYGETLIAAAGVFVTQEGVAVGENGVSFVWKKTLS"
     misc_feature    217047..218342
                     /gene="tilS"
                     /locus_tag="ECOK1_0189"
                     /note="tRNA(Ile)-lysidine synthetase; Provisional; Region:
                     tilS; PRK10660"
                     /db_xref="CDD:182626"
     misc_feature    217086..217634
                     /gene="tilS"
                     /locus_tag="ECOK1_0189"
                     /note="N-terminal domain of predicted ATPase of the
                     PP-loop faimly implicated in cell cycle control [Cell
                     division and chromosome partitioning]. This is a subfamily
                     of Adenine nucleotide alpha hydrolases
                     superfamily.Adeninosine nucleotide alpha hydrolases...;
                     Region: PP-ATPase; cd01992"
                     /db_xref="CDD:238950"
     misc_feature    order(217098..217106,217110..217121,217188..217190,
                     217194..217196)
                     /gene="tilS"
                     /locus_tag="ECOK1_0189"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238950"
     misc_feature    217767..217973
                     /gene="tilS"
                     /locus_tag="ECOK1_0189"
                     /note="TilS substrate binding domain; Region: TilS;
                     pfam09179"
                     /db_xref="CDD:255218"
     misc_feature    218112..218327
                     /gene="tilS"
                     /locus_tag="ECOK1_0189"
                     /note="TilS substrate C-terminal domain; Region: TilS_C;
                     pfam11734"
                     /db_xref="CDD:256581"
     gene            complement(218393..218653)
                     /gene="rof"
                     /locus_tag="ECOK1_0190"
                     /db_xref="GeneID:12688758"
     CDS             complement(218393..218653)
                     /gene="rof"
                     /locus_tag="ECOK1_0190"
                     /note="identified by similarity to SP:P0AFW8; match to
                     protein family HMM PF07073"
                     /codon_start=1
                     /transl_table=11
                     /product="rof protein"
                     /protein_id="YP_006099444.1"
                     /db_xref="GI:386597938"
                     /db_xref="GeneID:12688758"
                     /translation="MSINDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASD
                     LVSRKNVEYLVVEAAGATRELRLDKITSFSHPEIGTVVVSES"
     misc_feature    complement(218396..218647)
                     /gene="rof"
                     /locus_tag="ECOK1_0190"
                     /note="Rho-binding antiterminator; Provisional; Region:
                     PRK11625"
                     /db_xref="CDD:183241"
     gene            complement(218640..218840)
                     /locus_tag="ECOK1_0191"
                     /db_xref="GeneID:12688759"
     CDS             complement(218640..218840)
                     /locus_tag="ECOK1_0191"
                     /note="identified by match to protein family HMM PF06786"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099445.1"
                     /db_xref="GI:386597939"
                     /db_xref="GeneID:12688759"
                     /translation="MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALS
                     EAVREKAAYAAANLLVSDYVNK"
     misc_feature    complement(218643..218840)
                     /locus_tag="ECOK1_0191"
                     /note="hypothetical protein; Provisional; Region:
                     PRK04964"
                     /db_xref="CDD:179901"
     gene            219006..219551
                     /locus_tag="ECOK1_0192"
                     /db_xref="GeneID:12688760"
     CDS             219006..219551
                     /locus_tag="ECOK1_0192"
                     /note="identified by similarity to GB:AAN78721.1; match to
                     protein family HMM PF07152"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099446.1"
                     /db_xref="GI:386597940"
                     /db_xref="GeneID:12688760"
                     /translation="MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRL
                     LAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEV
                     ALFAYNSRAAQIWWQQNQSKCAQFANLSVWYLDDEQLAKVSAFADRTMTLQATIQDGV
                     IWLSDDKNNLEVNLTVWQQPS"
     misc_feature    219006..219548
                     /locus_tag="ECOK1_0192"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4681"
                     /db_xref="CDD:227026"
     gene            219548..219970
                     /locus_tag="ECOK1_0193"
                     /db_xref="GeneID:12688761"
     CDS             219548..219970
                     /locus_tag="ECOK1_0193"
                     /note="identified by match to protein family HMM PF00472"
                     /codon_start=1
                     /transl_table=11
                     /product="putative peptidyl-tRNA hydrolase"
                     /protein_id="YP_006099447.1"
                     /db_xref="GI:386597941"
                     /db_xref="GeneID:12688761"
                     /translation="MIVISRHVAIPDGEFEITAIRAQGAGGQHVNKTSTAIHLRFDIR
                     ASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRNQELNREAALARLVAVIKDLTTEQ
                     KARRPTRPTRASKERRLASKAQKSSVKAMRGKVRSGRE"
     misc_feature    219548..219955
                     /locus_tag="ECOK1_0193"
                     /note="hypothetical protein; Provisional; Region:
                     PRK09256"
                     /db_xref="CDD:181730"
     misc_feature    <219551..219967
                     /locus_tag="ECOK1_0193"
                     /note="Protein chain release factor B [Translation,
                     ribosomal structure and biogenesis]; Region: PrfB;
                     COG1186"
                     /db_xref="CDD:224107"
     gene            219984..220694
                     /gene="cutF"
                     /locus_tag="ECOK1_0194"
                     /db_xref="GeneID:12688762"
     CDS             219984..220694
                     /gene="cutF"
                     /locus_tag="ECOK1_0194"
                     /note="identified by match to protein family HMM PF04170"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutF"
                     /protein_id="YP_006099448.1"
                     /db_xref="GI:386597942"
                     /db_xref="GeneID:12688762"
                     /translation="MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTD
                     SKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEPAQSSLPMTPMTLRGMYFYMADAA
                     TFTDCATGKRFMVANNAELERGYLAARGNSEKPVLLSVEGHFTLEANPDTGAPTKVLA
                     PDTAGKFYPNQDCSSLGL"
     misc_feature    219984..220682
                     /gene="cutF"
                     /locus_tag="ECOK1_0194"
                     /note="lipoprotein involved with copper homeostasis and
                     adhesion; Provisional; Region: PRK10523"
                     /db_xref="CDD:236708"
     misc_feature    219984..220667
                     /gene="cutF"
                     /locus_tag="ECOK1_0194"
                     /note="Uncharacterized lipoprotein NlpE involved in copper
                     resistance [Cell envelope biogenesis, outer membrane /
                     Inorganic ion transport and metabolism]; Region: CutF;
                     COG3015"
                     /db_xref="CDD:225560"
     gene            complement(220850..221674)
                     /locus_tag="ECOK1_0195"
                     /db_xref="GeneID:12688763"
     CDS             complement(220850..221674)
                     /locus_tag="ECOK1_0195"
                     /note="identified by similarity to GB:ABB60443.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099449.1"
                     /db_xref="GI:386597943"
                     /db_xref="GeneID:12688763"
                     /translation="MDKPKAYCRLLLPCFLLLSACTVDISQPDSSATVVNAEAKTWAV
                     KFQHQSSFTEQSIKEITEPDLKPGDLLFSSSLGVTSFGIRVFSTSSVSHVAIYLGDNN
                     VAEATGAGVQIVSLKKAIKHSDKLFVLRVPDLTPQQATEITAFANKIKDSGYNYRGIV
                     EFIPFMVTRQMCSLNPFSEDFRQQCVSGLAKAQLSSVGEGDKKSWFCSEFVTDAFAKA
                     GHPLTLAQSGWISPADLMHMRSGDVSAFKPETQLQYIGHLKPGIYIKASRFVGLTQ"
     misc_feature    complement(220853..221674)
                     /locus_tag="ECOK1_0195"
                     /note="hypothetical protein; Provisional; Region:
                     PRK11479"
                     /db_xref="CDD:183157"
     misc_feature    complement(221327..>221503)
                     /locus_tag="ECOK1_0195"
                     /note="Cell wall-associated hydrolases
                     (invasion-associated proteins) [Cell envelope biogenesis,
                     outer membrane]; Region: Spr; COG0791"
                     /db_xref="CDD:223862"
     gene            complement(221727..223445)
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /db_xref="GeneID:12688764"
     CDS             complement(221727..223445)
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /EC_number="6.1.1.15"
                     /note="identified by match to protein family HMM PF00587;
                     match to protein family HMM PF03129; match to protein
                     family HMM PF04073; match to protein family HMM TIGR00409"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase"
                     /protein_id="YP_006099450.1"
                     /db_xref="GI:386597944"
                     /db_xref="GeneID:12688764"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGVRVLKKVENIVREEMNNAGAIEVLMPVVQPSELWQESGRWEQYGPELLRIADRGDR
                     PFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGE
                     DDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEK
                     TVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAG
                     PGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVA
                     GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     LDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYL
                     VKQIKG"
     misc_feature    complement(221733..223445)
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /note="prolyl-tRNA synthetase; Provisional; Region:
                     PRK09194"
                     /db_xref="CDD:236405"
     misc_feature    complement(222072..223397)
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /note="Prolyl-tRNA synthetase (ProRS) class II core
                     catalytic domain. ProRS is a homodimer. It is responsible
                     for the attachment of proline to the 3' OH group of ribose
                     of the appropriate tRNA. This domain is primarily
                     responsible for ATP-dependent...; Region: ProRS_core_prok;
                     cd00779"
                     /db_xref="CDD:238402"
     misc_feature    complement(order(222984..222986,223035..223037,
                     223095..223097,223149..223163,223167..223169,
                     223227..223232,223236..223244,223293..223295,
                     223314..223325,223344..223349))
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238402"
     misc_feature    complement(223227..223250)
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /note="motif 1; other site"
                     /db_xref="CDD:238402"
     misc_feature    complement(order(222096..222098,222105..222107,
                     222111..222119,222207..222209,222213..222218,
                     222222..222224,222969..222971,222975..222977,
                     222981..222983,222990..222998,223020..223022,
                     223026..223028,223113..223115,223119..223121))
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /note="active site"
                     /db_xref="CDD:238402"
     misc_feature    complement(223020..223031)
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /note="motif 2; other site"
                     /db_xref="CDD:238402"
     misc_feature    complement(222285..222770)
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /note="INS is an amino acid-editing domain inserted (INS)
                     into the bacterial class II prolyl-tRNA synthetase (ProRS)
                     however, this CD is not exclusively bacterial. It is also
                     found at the N-terminus of the eukaryotic/archaea-like
                     ProRS's of yeasts and...; Region: ProRS-INS; cd04334"
                     /db_xref="CDD:239826"
     misc_feature    complement(order(222360..222362,222435..222440,
                     222609..222611))
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /note="putative deacylase active site [active]"
                     /db_xref="CDD:239826"
     misc_feature    complement(222096..222113)
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /note="motif 3; other site"
                     /db_xref="CDD:238402"
     misc_feature    complement(221745..222029)
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /note="ProRS Prolyl-anticodon binding domain, short
                     version found predominantly in bacteria. ProRS belongs to
                     class II aminoacyl-tRNA synthetases (aaRS). This alignment
                     contains the anticodon binding domain, which is
                     responsible for specificity in tRNA-binding; Region:
                     ProRS_anticodon_short; cd00861"
                     /db_xref="CDD:238438"
     misc_feature    complement(order(221805..221807,221811..221813,
                     221841..221843,221865..221867,221883..221885,
                     222000..222005))
                     /gene="proS"
                     /locus_tag="ECOK1_0196"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:238438"
     gene            complement(223556..224263)
                     /locus_tag="ECOK1_0197"
                     /db_xref="GeneID:12688765"
     CDS             complement(223556..224263)
                     /locus_tag="ECOK1_0197"
                     /note="identified by match to protein family HMM PF01980;
                     match to protein family HMM TIGR00104"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="YP_006099451.1"
                     /db_xref="GI:386597945"
                     /db_xref="GeneID:12688765"
                     /translation="MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQ
                     ADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
                     MAVCFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVTDAGFEVFALEPR"
     misc_feature    complement(223850..224239)
                     /locus_tag="ECOK1_0197"
                     /note="Escherichia coli YaeB and related proteins; Region:
                     UPF0066; cd09281"
                     /db_xref="CDD:187753"
     misc_feature    complement(order(223850..223867,223964..223966,
                     223970..223972,223976..223978,223988..224005,
                     224078..224080,224090..224092,224111..224113,
                     224117..224125,224237..224239))
                     /locus_tag="ECOK1_0197"
                     /note="homodimer interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:187753"
     misc_feature    complement(order(223874..223876,223889..223891,
                     223958..223960,223964..223966,223988..223990,
                     224072..224077,224081..224083))
                     /locus_tag="ECOK1_0197"
                     /note="cofactor binding site; other site"
                     /db_xref="CDD:187753"
     gene            complement(224260..224664)
                     /gene="rcsF"
                     /locus_tag="ECOK1_0198"
                     /db_xref="GeneID:12688766"
     CDS             complement(224260..224664)
                     /gene="rcsF"
                     /locus_tag="ECOK1_0198"
                     /note="identified by similarity to SP:P69411"
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide synthesis regulator RcsF"
                     /protein_id="YP_006099452.1"
                     /db_xref="GI:386597946"
                     /db_xref="GeneID:12688766"
                     /translation="MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAP
                     RATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKAN
                     AVLLHSCEVTSGTPGCYRQAVCIGSALNITAK"
     misc_feature    complement(224266..224664)
                     /gene="rcsF"
                     /locus_tag="ECOK1_0198"
                     /note="outer membrane lipoprotein; Reviewed; Region: rcsF;
                     PRK10781"
                     /db_xref="CDD:182725"
     gene            complement(224782..225597)
                     /gene="metQ"
                     /locus_tag="ECOK1_0199"
                     /db_xref="GeneID:12688767"
     CDS             complement(224782..225597)
                     /gene="metQ"
                     /locus_tag="ECOK1_0199"
                     /note="identified by similarity to SP:P28635; match to
                     protein family HMM PF03180; match to protein family HMM
                     TIGR00363"
                     /codon_start=1
                     /transl_table=11
                     /product="D-methionine ABC transporter substrate-binding
                     protein"
                     /protein_id="YP_006099453.1"
                     /db_xref="GI:386597947"
                     /db_xref="GeneID:12688767"
                     /translation="MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDRGYK
                     LVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
                     FVEDKESPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     misc_feature    complement(224815..225504)
                     /gene="metQ"
                     /locus_tag="ECOK1_0199"
                     /note="Toll-like receptor 2-activating lipoprotein IlpA
                     from Vibrio vulnificus and similar lipoproteins; the type
                     2 periplasmic binding protein fold; Region:
                     PBP2_lipoprotein_IlpA_like; cd13598"
                     /db_xref="CDD:270316"
     misc_feature    complement(order(224911..224913,224986..224988,
                     224992..224994,225166..225168,225175..225177,
                     225262..225264,225325..225327,225334..225342,
                     225391..225393))
                     /gene="metQ"
                     /locus_tag="ECOK1_0199"
                     /note="chemical substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:270316"
     gene            complement(225637..226290)
                     /gene="metI"
                     /locus_tag="ECOK1_0200"
                     /db_xref="GeneID:12688768"
     CDS             complement(225637..226290)
                     /gene="metI"
                     /locus_tag="ECOK1_0200"
                     /note="identified by similarity to SP:P31547; match to
                     protein family HMM PF00528"
                     /codon_start=1
                     /transl_table=11
                     /product="D-methionine ABC transporter permease"
                     /protein_id="YP_006099454.1"
                     /db_xref="GI:386597948"
                     /db_xref="GeneID:12688768"
                     /translation="MSEPMIWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
                     QIIANAKLYRTISAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAP
                     FIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK"
     misc_feature    complement(225760..226251)
                     /gene="metI"
                     /locus_tag="ECOK1_0200"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(225793..225798,225805..225816,
                     225835..225837,225844..225849,225889..225891,
                     225940..225942,225949..225954,225964..225966,
                     225970..225975,225982..225984,225988..225990,
                     225994..225999,226063..226065,226069..226074,
                     226081..226110,226114..226125,226174..226176,
                     226189..226194,226201..226206))
                     /gene="metI"
                     /locus_tag="ECOK1_0200"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(225799..225816,226063..226107))
                     /gene="metI"
                     /locus_tag="ECOK1_0200"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(225760..225762,225796..225798,
                     226012..226014,226063..226065))
                     /gene="metI"
                     /locus_tag="ECOK1_0200"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(225868..225870,225880..225885,
                     225901..225939))
                     /gene="metI"
                     /locus_tag="ECOK1_0200"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(226283..227314)
                     /gene="metN"
                     /locus_tag="ECOK1_0201"
                     /db_xref="GeneID:12688769"
     CDS             complement(226283..227314)
                     /gene="metN"
                     /locus_tag="ECOK1_0201"
                     /note="identified by similarity to SP:P30750; match to
                     protein family HMM PF00005; match to protein family HMM
                     PF09383; match to protein family HMM TIGR02314"
                     /codon_start=1
                     /transl_table=11
                     /product="D-methionine ABC transporter ATP-binding
                     protein"
                     /protein_id="YP_006099455.1"
                     /db_xref="GI:386597949"
                     /db_xref="GeneID:12688769"
                     /translation="MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKDEIKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHH
                     VKVEVLGYV"
     misc_feature    complement(226286..227314)
                     /gene="metN"
                     /locus_tag="ECOK1_0201"
                     /note="DL-methionine transporter ATP-binding subunit;
                     Provisional; Region: metN; PRK11153"
                     /db_xref="CDD:236863"
     misc_feature    complement(226616..227314)
                     /gene="metN"
                     /locus_tag="ECOK1_0201"
                     /note="ATP-binding cassette domain of methionine
                     transporter; Region: ABC_MetN_methionine_transporter;
                     cd03258"
                     /db_xref="CDD:213225"
     misc_feature    complement(227180..227203)
                     /gene="metN"
                     /locus_tag="ECOK1_0201"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(order(226718..226720,226817..226822,
                     227048..227050,227177..227185,227189..227194))
                     /gene="metN"
                     /locus_tag="ECOK1_0201"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(227048..227059)
                     /gene="metN"
                     /locus_tag="ECOK1_0201"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(226865..226894)
                     /gene="metN"
                     /locus_tag="ECOK1_0201"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(226817..226834)
                     /gene="metN"
                     /locus_tag="ECOK1_0201"
                     /note="Walker B; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(226799..226810)
                     /gene="metN"
                     /locus_tag="ECOK1_0201"
                     /note="D-loop; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(226712..226732)
                     /gene="metN"
                     /locus_tag="ECOK1_0201"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213225"
     misc_feature    complement(226295..226516)
                     /gene="metN"
                     /locus_tag="ECOK1_0201"
                     /note="This domain is found at the C-terminus of ABC
                     transporter proteins involved in D-methionine transport as
                     well as a number of ferredoxin-like proteins; Region: NIL;
                     smart00930"
                     /db_xref="CDD:197998"
     gene            227502..228074
                     /locus_tag="ECOK1_0202"
                     /db_xref="GeneID:12688770"
     CDS             227502..228074
                     /locus_tag="ECOK1_0202"
                     /note="identified by match to protein family HMM PF08645;
                     match to protein family HMM TIGR00213; match to protein
                     family HMM TIGR01656; match to protein family HMM
                     TIGR01662"
                     /codon_start=1
                     /transl_table=11
                     /product="D,D-heptose 1,7-bisphosphate phosphatase"
                     /protein_id="YP_006099456.1"
                     /db_xref="GI:386597950"
                     /db_xref="GeneID:12688770"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKK
                     MGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEE
                     FRQVCDCRKPHPGMFLSARDYLHIDMAASYMVGDKLEDMQAAAAASVGTKVLVRTGKP
                     ITPEAENAADWVLNSLADLPQAIKKQQKPA"
     misc_feature    227514..228044
                     /locus_tag="ECOK1_0202"
                     /note="D,D-heptose 1,7-bisphosphate phosphatase; Region:
                     GmhB_yaeD; TIGR00213"
                     /db_xref="CDD:129317"
     misc_feature    227520..227966
                     /locus_tag="ECOK1_0202"
                     /note="Haloacid dehalogenase-like hydrolases. The haloacid
                     dehalogenase-like (HAD) superfamily includes L-2-haloacid
                     dehalogenase, epoxide hydrolase, phosphoserine
                     phosphatase, phosphomannomutase, phosphoglycolate
                     phosphatase, P-type ATPase, and many others; Region:
                     HAD_like; cd01427"
                     /db_xref="CDD:119389"
     misc_feature    order(227532..227540,227658..227663)
                     /locus_tag="ECOK1_0202"
                     /note="active site"
                     /db_xref="CDD:119389"
     misc_feature    227532..227549
                     /locus_tag="ECOK1_0202"
                     /note="motif I; other site"
                     /db_xref="CDD:119389"
     misc_feature    227658..227660
                     /locus_tag="ECOK1_0202"
                     /note="motif II; other site"
                     /db_xref="CDD:119389"
     gene            228440..229981
                     /gene="rrsA"
                     /locus_tag="ECOK1_0203"
                     /db_xref="GeneID:12688771"
     rRNA            228440..229981
                     /gene="rrsA"
                     /locus_tag="ECOK1_0203"
                     /product="16S ribosomal RNA"
                     /db_xref="GeneID:12688771"
     gene            230050..230126
                     /locus_tag="ECOK1_0204"
                     /db_xref="GeneID:12688772"
     tRNA            230050..230126
                     /locus_tag="ECOK1_0204"
                     /product="tRNA-Ile"
                     /db_xref="GeneID:12688772"
     gene            230169..230244
                     /locus_tag="ECOK1_0205"
                     /db_xref="GeneID:12688773"
     tRNA            230169..230244
                     /locus_tag="ECOK1_0205"
                     /product="tRNA-Ala"
                     /db_xref="GeneID:12688773"
     gene            230419..233322
                     /gene="rrlA"
                     /locus_tag="ECOK1_0206"
                     /db_xref="GeneID:12688774"
     rRNA            230419..233322
                     /gene="rrlA"
                     /locus_tag="ECOK1_0206"
                     /product="23S ribosomal RNA"
                     /db_xref="GeneID:12688774"
     gene            233421..233540
                     /gene="rrfA"
                     /locus_tag="ECOK1_0207"
                     /db_xref="GeneID:12688775"
     rRNA            233421..233540
                     /gene="rrfA"
                     /locus_tag="ECOK1_0207"
                     /product="5S ribosomal RNA"
                     /db_xref="GeneID:12688775"
     gene            233592..233668
                     /locus_tag="ECOK1_0208"
                     /db_xref="GeneID:12688776"
     tRNA            233592..233668
                     /locus_tag="ECOK1_0208"
                     /product="tRNA-Asp"
                     /db_xref="GeneID:12688776"
     gene            233831..234634
                     /gene="dkgB"
                     /locus_tag="ECOK1_0210"
                     /db_xref="GeneID:12688777"
     CDS             233831..234634
                     /gene="dkgB"
                     /locus_tag="ECOK1_0210"
                     /EC_number="1.1.1.274"
                     /note="identified by similarity to SP:P30863; match to
                     protein family HMM PF00248"
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase"
                     /protein_id="YP_006099457.1"
                     /db_xref="GI:386597951"
                     /db_xref="GeneID:12688777"
                     /translation="MAIPAFGLGTFRLKDDVVISSVKTALELDYRAIDTAQIYDNEAA
                     VGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPS
                     DEVSAEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQ
                     NRKVVAWAKQHGIHITSYMTLAYGNALKDKVIARIAAKHNATPAQVILAWAMGEGYSV
                     IPSSTKRENLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD"
     misc_feature    233837..234580
                     /gene="dkgB"
                     /locus_tag="ECOK1_0210"
                     /note="Aldo-keto reductases (AKRs) are a superfamily of
                     soluble NAD(P)(H) oxidoreductases whose chief purpose is
                     to reduce aldehydes and ketones to primary and secondary
                     alcohols. AKRs are present in all phyla and are of
                     importance to both health and industrial...; Region:
                     Aldo_ket_red; cd06660"
                     /db_xref="CDD:119408"
     misc_feature    233837..234547
                     /gene="dkgB"
                     /locus_tag="ECOK1_0210"
                     /note="voltage-dependent potassium channel beta subunit,
                     animal; Region: Kv_beta; TIGR01293"
                     /db_xref="CDD:213602"
     misc_feature    order(233855..233863,233930..233932,233945..233947,
                     234020..234022,234119..234124,234215..234220,
                     234284..234286,234362..234379,234440..234442,
                     234485..234496,234509..234511,234518..234523)
                     /gene="dkgB"
                     /locus_tag="ECOK1_0210"
                     /note="active site"
                     /db_xref="CDD:119408"
     misc_feature    order(233930..233932,233945..233947,234020..234022,
                     234119..234121)
                     /gene="dkgB"
                     /locus_tag="ECOK1_0210"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:119408"
     gene            complement(234631..235545)
                     /locus_tag="ECOK1_0209"
                     /db_xref="GeneID:12688778"
     CDS             complement(234631..235545)
                     /locus_tag="ECOK1_0209"
                     /note="identified by match to protein family HMM PF00126;
                     match to protein family HMM PF03466"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_006099458.1"
                     /db_xref="GI:386597952"
                     /db_xref="GeneID:12688778"
                     /translation="MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGERYFHRVQSILQEMAAAESEIMETRNTPRGLLRIDAATP
                     VVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
                     NSYRKIIASPDYISCYGKPETIDDLKQHICLRFTEPASLNTWPIACSDGQLHEVKYGL
                     SSNSGETLKQLCLSGNGIACLSDYMIDKEIARGELVELMADKVLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSGHVKTAPGGAVREA"
     misc_feature    complement(234664..235530)
                     /locus_tag="ECOK1_0209"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    complement(235354..235524)
                     /locus_tag="ECOK1_0209"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    complement(234679..235275)
                     /locus_tag="ECOK1_0209"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulator CrgA, contains the
                     type 2 periplasmic binding domain; Region: PBP2_CrgA;
                     cd08478"
                     /db_xref="CDD:176167"
     misc_feature    complement(order(234742..234744,234826..234828,
                     234877..234879,235060..235062,235066..235068,
                     235108..235110,235225..235227,235237..235239))
                     /locus_tag="ECOK1_0209"
                     /note="putative effector binding pocket; other site"
                     /db_xref="CDD:176167"
     misc_feature    complement(order(234850..234852,234859..234864,
                     234883..234897,234979..234981,235162..235182,
                     235186..235188,235198..235200,235207..235212,
                     235216..235221,235231..235236))
                     /locus_tag="ECOK1_0209"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176167"
     gene            235786..236586
                     /locus_tag="ECOK1_0211"
                     /db_xref="GeneID:12688779"
     CDS             235786..236586
                     /locus_tag="ECOK1_0211"
                     /note="identified by match to protein family HMM PF03372"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="YP_006099459.1"
                     /db_xref="GI:386597953"
                     /db_xref="GeneID:12688779"
                     /translation="MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERI
                     RILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
                     LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNF
                     SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTD
                     DQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK"
     misc_feature    235786..236574
                     /locus_tag="ECOK1_0211"
                     /note="hypothetical protein; Provisional; Region:
                     PRK05421"
                     /db_xref="CDD:235454"
     misc_feature    order(235933..235935,236014..236016,236251..236253,
                     236353..236355,236359..236361)
                     /locus_tag="ECOK1_0211"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:197306"
     misc_feature    236014..236016
                     /locus_tag="ECOK1_0211"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:197306"
     misc_feature    order(236251..236253,236359..236361)
                     /locus_tag="ECOK1_0211"
                     /note="putative phosphate binding site [ion binding];
                     other site"
                     /db_xref="CDD:197306"
     misc_feature    order(236353..236355,236359..236361,236473..236475,
                     236536..236541)
                     /locus_tag="ECOK1_0211"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:197306"
     misc_feature    order(236359..236361,236539..236541)
                     /locus_tag="ECOK1_0211"
                     /note="putative phosphate binding site [ion binding];
                     other site"
                     /db_xref="CDD:197306"
     misc_feature    236536..236538
                     /locus_tag="ECOK1_0211"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:197306"
     gene            236664..237434
                     /locus_tag="ECOK1_0212"
                     /db_xref="GeneID:12688780"
     CDS             236664..237434
                     /locus_tag="ECOK1_0212"
                     /note="identified by match to protein family HMM PF01209;
                     match to protein family HMM PF08241; match to protein
                     family HMM PF08242"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiE/COQ5 family methyltransferase"
                     /protein_id="YP_006099460.1"
                     /db_xref="GI:386597954"
                     /db_xref="GeneID:12688780"
                     /translation="MTTQSHHDHVEKQFSSQASEYLTSTVHASGRDLQRLAVRLADYP
                     DASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAE
                     SLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWL
                     QTVEALRDTSHVRNYASGEWLRLINEANLIVDNLITDKLPLEFSSWVARMRTPEALVD
                     AIRIYQQSASTEVKTYFALQNDGSFTSDIIMVEAHKAA"
     misc_feature    236793..237227
                     /locus_tag="ECOK1_0212"
                     /note="Methyltransferase domain; Region: Methyltransf_31;
                     pfam13847"
                     /db_xref="CDD:258120"
     misc_feature    236805..237107
                     /locus_tag="ECOK1_0212"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(236814..236834,236880..236885,236958..236966,
                     237012..237014)
                     /locus_tag="ECOK1_0212"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(237481..238839)
                     /gene="mltD"
                     /locus_tag="ECOK1_0213"
                     /db_xref="GeneID:12688781"
     CDS             complement(237481..238839)
                     /gene="mltD"
                     /locus_tag="ECOK1_0213"
                     /EC_number="2.4.-.-"
                     /note="identified by similarity to SP:P0AEZ7; match to
                     protein family HMM PF01464; match to protein family HMM
                     PF01476; match to protein family HMM PF06474"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase D"
                     /protein_id="YP_006099461.1"
                     /db_xref="GI:386597955"
                     /db_xref="GeneID:12688781"
                     /translation="MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQA
                     RWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYM
                     YWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNY
                     DARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDF
                     WSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVAD
                     MAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVAD
                     NTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQR
                     LANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNNMP
                     DS"
     misc_feature    complement(237484..238839)
                     /gene="mltD"
                     /locus_tag="ECOK1_0213"
                     /note="membrane-bound lytic murein transglycosylase D;
                     Provisional; Region: mltD; PRK10783"
                     /db_xref="CDD:182727"
     misc_feature    complement(238123..238497)
                     /gene="mltD"
                     /locus_tag="ECOK1_0213"
                     /note="Lytic Transglycosylase (LT)  and Goose Egg White
                     Lysozyme (GEWL) domain. Members include the soluble and
                     insoluble membrane-bound LTs in bacteria, the LTs in
                     bacteriophage lambda, as well as, the eukaryotic
                     'goose-type' lysozymes (GEWL).  LTs...; Region: LT_GEWL;
                     cd00254"
                     /db_xref="CDD:238157"
     misc_feature    complement(order(238255..238257,238312..238314,
                     238405..238407,238465..238467))
                     /gene="mltD"
                     /locus_tag="ECOK1_0213"
                     /note="N-acetyl-D-glucosamine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:238157"
     misc_feature    complement(238465..238467)
                     /gene="mltD"
                     /locus_tag="ECOK1_0213"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238157"
     misc_feature    complement(237688..237819)
                     /gene="mltD"
                     /locus_tag="ECOK1_0213"
                     /note="Lysine Motif is a small domain involved in binding
                     peptidoglycan; Region: LysM; cd00118"
                     /db_xref="CDD:212030"
     misc_feature    complement(237514..237642)
                     /gene="mltD"
                     /locus_tag="ECOK1_0213"
                     /note="Lysine Motif is a small domain involved in binding
                     peptidoglycan; Region: LysM; cd00118"
                     /db_xref="CDD:212030"
     gene            complement(238911..239666)
                     /gene="gloB"
                     /locus_tag="ECOK1_0214"
                     /db_xref="GeneID:12688782"
     CDS             complement(238911..239666)
                     /gene="gloB"
                     /locus_tag="ECOK1_0214"
                     /EC_number="3.1.2.6"
                     /note="identified by similarity to SP:P0AC84; match to
                     protein family HMM PF00753; match to protein family HMM
                     TIGR03413"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="YP_006099462.1"
                     /db_xref="GI:386597956"
                     /db_xref="GeneID:12688782"
                     /translation="MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAISANNW
                     QPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEF
                     SVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTPSQMYQSIKKLSALPDDTL
                     VCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLR
                     TEDIDLINVINEETLLQQPEERFAWLRSKKDRF"
     misc_feature    complement(238914..239666)
                     /gene="gloB"
                     /locus_tag="ECOK1_0214"
                     /note="hydroxyacylglutathione hydrolase; Provisional;
                     Region: PRK10241"
                     /db_xref="CDD:182327"
     gene            239700..240422
                     /locus_tag="ECOK1_0216"
                     /db_xref="GeneID:12688783"
     CDS             239700..240422
                     /locus_tag="ECOK1_0216"
                     /note="identified by match to protein family HMM PF08241"
                     /codon_start=1
                     /transl_table=11
                     /product="putative methyltransferase"
                     /protein_id="YP_006099463.1"
                     /db_xref="GI:386597957"
                     /db_xref="GeneID:12688783"
                     /translation="MKPARVPQTVVAPDCWGDLPWGELYRKALERQLNPWFTKMYGFH
                     LLKIGNLSAEINCEACAVSHQVNVSAQGMPVQVQADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLREADRVLIDDGWLVISGFNPISLMGLRKLVPVLRKTSPYNSRMFTLMRQL
                     DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQ
                     SKNKPRIRQAVGATRQCRKPQA"
     misc_feature    <239859..240077
                     /locus_tag="ECOK1_0216"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     gene            complement(240419..240886)
                     /gene="rnhA"
                     /locus_tag="ECOK1_0215"
                     /db_xref="GeneID:12688784"
     CDS             complement(240419..240886)
                     /gene="rnhA"
                     /locus_tag="ECOK1_0215"
                     /EC_number="3.1.26.4"
                     /note="identified by match to protein family HMM PF00075"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H"
                     /protein_id="YP_006099464.1"
                     /db_xref="GI:386597958"
                     /db_xref="GeneID:12688784"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTN
                     NRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVD
                     LWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV"
     misc_feature    complement(240464..240877)
                     /gene="rnhA"
                     /locus_tag="ECOK1_0215"
                     /note="RNase HI family found mainly in prokaryotes;
                     Region: RNase_HI_prokaryote_like; cd09278"
                     /db_xref="CDD:260010"
     misc_feature    complement(order(240473..240475,240527..240529,
                     240677..240679,240743..240745,240752..240760,
                     240848..240859))
                     /gene="rnhA"
                     /locus_tag="ECOK1_0215"
                     /note="RNA/DNA hybrid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:260010"
     misc_feature    complement(order(240485..240487,240677..240679,
                     240743..240745,240857..240859))
                     /gene="rnhA"
                     /locus_tag="ECOK1_0215"
                     /note="active site"
                     /db_xref="CDD:260010"
     gene            240951..241682
                     /gene="dnaQ"
                     /locus_tag="ECOK1_0217"
                     /db_xref="GeneID:12688785"
     CDS             240951..241682
                     /gene="dnaQ"
                     /locus_tag="ECOK1_0217"
                     /EC_number="2.7.7.7"
                     /note="identified by similarity to SP:P03007; match to
                     protein family HMM PF00929; match to protein family HMM
                     TIGR00573; match to protein family HMM TIGR01406"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="YP_006099465.1"
                     /db_xref="GI:386597959"
                     /db_xref="GeneID:12688785"
                     /translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLT
                     GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAF
                     DIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRT
                     LHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGETTIQRIVRQASKLRVVFAT
                     DEELAAHEARLDLVQKKGGSCLWRA"
     misc_feature    240969..241658
                     /gene="dnaQ"
                     /locus_tag="ECOK1_0217"
                     /note="DNA polymerase III, epsilon subunit,
                     Proteobacterial; Region: dnaQ_proteo; TIGR01406"
                     /db_xref="CDD:130473"
     misc_feature    240972..241487
                     /gene="dnaQ"
                     /locus_tag="ECOK1_0217"
                     /note="DEDDh 3'-5' exonuclease domain of the epsilon
                     subunit of Escherichia coli DNA polymerase III and similar
                     proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131"
                     /db_xref="CDD:99835"
     misc_feature    order(240984..240995,240999..241004,241131..241136,
                     241143..241148,241242..241247,241251..241259,
                     241380..241385,241425..241427,241434..241436,
                     241449..241451)
                     /gene="dnaQ"
                     /locus_tag="ECOK1_0217"
                     /note="active site"
                     /db_xref="CDD:99835"
     misc_feature    order(240984..240995,240999..241004,241131..241136,
                     241143..241148,241242..241247,241251..241256,
                     241380..241385,241425..241427,241434..241436,
                     241449..241451)
                     /gene="dnaQ"
                     /locus_tag="ECOK1_0217"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99835"
     misc_feature    order(240984..240986,240990..240992,241257..241259,
                     241434..241436,241449..241451)
                     /gene="dnaQ"
                     /locus_tag="ECOK1_0217"
                     /note="catalytic site [active]"
                     /db_xref="CDD:99835"
     gene            241815..241891
                     /locus_tag="ECOK1_0218"
                     /db_xref="GeneID:12688786"
     tRNA            241815..241891
                     /locus_tag="ECOK1_0218"
                     /product="tRNA-Asp"
                     /db_xref="GeneID:12688786"
     gene            242023..242166
                     /locus_tag="ECOK1_0219"
                     /db_xref="GeneID:12688787"
     CDS             242023..242166
                     /locus_tag="ECOK1_0219"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099466.1"
                     /db_xref="GI:386597960"
                     /db_xref="GeneID:12688787"
                     /translation="MSLIFNHAIESFNLNIFARYDFHFSIDLMNLYLLLFFVCSDSSG
                     VYN"
     gene            242220..243005
                     /locus_tag="ECOK1_0220"
                     /db_xref="GeneID:12688788"
     CDS             242220..243005
                     /locus_tag="ECOK1_0220"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipoprotein"
                     /protein_id="YP_006099467.1"
                     /db_xref="GI:386597961"
                     /db_xref="GeneID:12688788"
                     /translation="MNLKKVCCICVLFSLLAGCASESPIDEKKKKTQTTQISINKNVP
                     QQLTDKDLYGNETTLAVSEEDIQAALEGDEFRVPLNSPVILVQSGSRAPETIMQEEMR
                     KYYTVATFSGIPDRKKTVTCNKDKNKDESLDIVDAENMNWMQALRFVAAKGHQKAIIV
                     FQDTLQTGKYDSGLKSIVWTDYKNQKLTDTMSLRYLVRFTLVDVATGEWATWSPVNYE
                     SKVIFPQIGNKNSDSLDVAEQQISQLKQKTYAAVVKDLVNRYQ"
     gene            complement(243345..243824)
                     /locus_tag="ECOK1_0221"
                     /db_xref="GeneID:12688789"
     CDS             complement(243345..243824)
                     /locus_tag="ECOK1_0221"
                     /note="identified by similarity to GB:CAE12300.1; match to
                     protein family HMM PF05638; match to protein family HMM
                     TIGR03344"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099468.1"
                     /db_xref="GI:386597962"
                     /db_xref="GeneID:12688789"
                     /translation="MANPVYLTLNGELQGLISSGCSSMPSIGNKAQIAHQDQIMVTSL
                     SHGLSRAQNVNHQELTITKPVDKSSPLLGKAISENECLTCDFVFYRTNRFGINEPYYK
                     LKLANARLSNIGLTVPHTINDSPGQAEESVSFTYESINWEHSVAGTSAYSLWSERIF"
     misc_feature    complement(243354..243821)
                     /locus_tag="ECOK1_0221"
                     /note="type VI secretion system effector, Hcp1 family;
                     Region: VI_effect_Hcp1; TIGR03344"
                     /db_xref="CDD:213799"
     gene            complement(243842..245200)
                     /locus_tag="ECOK1_0222"
                     /db_xref="GeneID:12688790"
     CDS             complement(243842..245200)
                     /locus_tag="ECOK1_0222"
                     /note="identified by match to protein family HMM PF06812"
                     /codon_start=1
                     /transl_table=11
                     /product="ImpA domain-containing protein"
                     /protein_id="YP_006099469.1"
                     /db_xref="GI:386597963"
                     /db_xref="GeneID:12688790"
                     /translation="MSNYALTQTIVTGSDPRALPEFSAIREEINKANHPSQPELNWKL
                     VESLALSIFKANGVDLHTATYYTLARTRNQGLAGFCEGAELLAAMIIHEWDKFWPQSG
                     PARTEMLDWFNTRTGNILRQQVSFSENDLSLLYRTERALQLICDKLQQVELKRQPRVE
                     NLLYFVQNTRKRFEPQPRNRTDTAAQTMVRTLVYAPEGTASATAETMPPLPDLPEMRV
                     GVRGVADNADKAKQGDTVKGFVAGAACTAVIASALWWWQAYPMQQQLTQVRDTTQGAA
                     TVWLASPVLKEYEQYLQQLLNAPPLQPLETGMQMMRTADTLWPESLQQQEASRMWSNT
                     LRNRAQASPQMKGWQQARQNLRDFADLMMKKETEKQGFTLSYIKTVTWQAERLLNQET
                     PLEYLLTQYQETRTQKQDTQALEKEINERLDGLLSRWLLLKNTGQDMATDNRTEPVHP
                     TH"
     misc_feature    complement(244208..245200)
                     /locus_tag="ECOK1_0222"
                     /note="Predicted component of the type VI protein
                     secretion system [Intracellular trafficking, secretion,
                     and    vesicular transport]; Region: COG3515"
                     /db_xref="CDD:226046"
     misc_feature    complement(244895..245080)
                     /locus_tag="ECOK1_0222"
                     /note="ImpA-related N-terminal; Region: ImpA-rel_N;
                     pfam06812"
                     /db_xref="CDD:253924"
     misc_feature    complement(243899..244339)
                     /locus_tag="ECOK1_0222"
                     /note="ImpA domain protein; Region: DUF3702; pfam12486"
                     /db_xref="CDD:193049"
     gene            complement(245211..248678)
                     /locus_tag="ECOK1_0223"
                     /db_xref="GeneID:12688791"
     CDS             complement(245211..248678)
                     /locus_tag="ECOK1_0223"
                     /note="identified by similarity to GB:AAQ96724.1; match to
                     protein family HMM PF06744; match to protein family HMM
                     PF06761; match to protein family HMM TIGR03348"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099470.1"
                     /db_xref="GI:386597964"
                     /db_xref="GeneID:12688791"
                     /translation="MPRFKVSATWLLTLAWIFLLVWIWWQGPKWTLYEQHWLAPLANR
                     WLATAVWGLIALVWLTWRVMKRLQKLEKQQKQQREEEKDPLTVELHRQQQYLDHWLLR
                     LRRHLDNRRYLWQLPWYMVIGPAGSGKSTLLREGFPSDIVYTPESIRGVEYHPLITPR
                     VGNQAVIFDVDGVLTTPGGDDLLRRRLREHWLGWLMQTRARQPLNGLILTLDLPDLLT
                     ADKSRRETLVQNLRQQLQEIRQSLHCRLPVYVVLTRLDLLNGFAALFHSLDKKDRDAI
                     LGVTFTRRAHESDGWRSELGAFWQTWVQQVNLALSDLVLAQTGAAPRSAVFSFSRQMQ
                     GTGEIVTALLAALLDGENMDVMLRGVWLTSSLQRGQVDDIFTQSAARQYGLGNSSLAT
                     WPLVETTPYFTRRLFPEVLLAEPNLAGENSVWLNSSRRRLTAFSTCGAALAALMVGSW
                     HHYYNQNWQSGVNVLAQAKAFMDVPPPQGTDEFGNLQLPLLNPVRDATLAYGDYRDHG
                     FLADMGLYQGARVGPYVEQTYIQLLEQRYLPSLMNGLIRDLNIAPPESEEKLAVLRVV
                     RMMEDKSGRNNEAVKQYMARRWSNEFHGQRDIQAQLMVHLDYALEHTDWHAQRQSSDS
                     DAVSRWTPYDKPIINAQQELSKLPIYQRVYQTLRTKALSVLPADLNLRDQVGPTFDNV
                     FVAGNDEKLVIPQFLTRYGLQSYFVKQREGLVELTALDSWVLNLTQSVAYSEADREEI
                     QRHITEQYISDYTATWRAGMDNLNVRDYEAMSALTDALEQIISGDQPFQRALTALRDN
                     THALTLSGKLDDKAREAAINEMDYRLLSRLGHEFAPENSALEEQKDKASTLQAVYQQL
                     TELHRYLLAIQNSPVPGKSALKAVQLRLDQNSSDPIFATRQMAKTLPAPLNRWVGKLA
                     DQAWHVVMVEAVRYMEVDWRDNVVKPFNEQLADNYPFNPRATQDASLDSFERFFKPDG
                     ILDNFYKNNLRLFLENDLTFGDDGRVLIREDIRQQLDTAQKIRDIFFSQQNGLGAQFA
                     VETVSLSGNKRRSVLNLDGQLVDYSQGRNYTAHLVWPNNMREGNESKLTLIGTSGRAP
                     RSIAFSGPWAQFRLFGAGQLTNVTSDTFNVRFNVDGGAMVYQVHVDTEDNPFTGGLFS
                     LFRLPDTLY"
     misc_feature    complement(245214..248675)
                     /locus_tag="ECOK1_0223"
                     /note="Type VI protein secretion system component VasK
                     [Intracellular trafficking, secretion, and    vesicular
                     transport]; Region: IcmF; COG3523"
                     /db_xref="CDD:226054"
     misc_feature    complement(247344..248126)
                     /locus_tag="ECOK1_0223"
                     /note="ImcF-related N-terminal domain; Region:
                     ImcF-related_N; pfam14331"
                     /db_xref="CDD:258504"
     misc_feature    complement(246276..247220)
                     /locus_tag="ECOK1_0223"
                     /note="Intracellular multiplication and human
                     macrophage-killing; Region: IcmF-related; pfam06761"
                     /db_xref="CDD:253899"
     misc_feature    complement(245637..245996)
                     /locus_tag="ECOK1_0223"
                     /note="Protein of unknown function (DUF1215); Region:
                     DUF1215; pfam06744"
                     /db_xref="CDD:253889"
     gene            complement(248758..250200)
                     /locus_tag="ECOK1_0224"
                     /db_xref="GeneID:12688792"
     CDS             complement(248758..250200)
                     /locus_tag="ECOK1_0224"
                     /note="identified by similarity to GB:AAS64092.1; match to
                     protein family HMM TIGR03362"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099471.1"
                     /db_xref="GI:386597965"
                     /db_xref="GeneID:12688792"
                     /translation="MAMDLRNPDVWLAHLLENLPEDKLSAALDDGNADWEFVDSEIVK
                     LGSLAHSQLDIPELQRRGLMLLASETKDFRLLAHLLRTLQHAGDILLASRMLAQYTEH
                     YWTCAAPQNMAHKKRFAAQVIKRFESAVQDFAGNAATIQRDALLGELAKLAQCWQAHN
                     ASELAKATDDLFSLFQRAFRDVAPEMTSSARSAAIAPQATTGYVPDMSPHTVAAQPPV
                     AATPIPQVTVENHDDKAWRDTLLKVAAILCERQPESPQGYRLRRHALWQTITSTPQAE
                     SDGRTPLAAFPVDMMDDYLARLNNADMALWQQVEKSLLLAPYWLDGHYLSAQTALRLG
                     YKQVADAIRDEVTDFLARLPALINLLFNDRTPFVSEQTKQWLASSGSVNQTVPVVQTD
                     EELQAAKACFDENGLEAALRYLENLPEGDPRHQFHRQFFGAQLLEEAGMVQLAQQQYR
                     MLFRTGLHMMLSEWEPSLLKALEQKLTAEQ"
     misc_feature    complement(249871..250041)
                     /locus_tag="ECOK1_0224"
                     /note="ImpA-related N-terminal; Region: ImpA-rel_N;
                     cl19907"
                     /db_xref="CDD:268260"
     misc_feature    complement(248770..249642)
                     /locus_tag="ECOK1_0224"
                     /note="type VI secretion-associated protein, VC_A0119
                     family; Region: VI_chp_7; TIGR03362"
                     /db_xref="CDD:234184"
     misc_feature    complement(248761..249555)
                     /locus_tag="ECOK1_0224"
                     /note="Predicted component of the type VI protein
                     secretion system [Intracellular trafficking, secretion,
                     and    vesicular transport]; Region: COG3515"
                     /db_xref="CDD:226046"
     gene            complement(250205..250948)
                     /locus_tag="ECOK1_0225"
                     /db_xref="GeneID:12688793"
     CDS             complement(250205..250948)
                     /locus_tag="ECOK1_0225"
                     /note="identified by match to protein family HMM
                     TIGR03360"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099472.1"
                     /db_xref="GI:386597966"
                     /db_xref="GeneID:12688793"
                     /translation="MSRLCVFRQTGWFIAGLMAGLPASAAPTETSSVAGVAVAVATAT
                     PPDATATLQAMQSCRQETAALERLDCYDRILAPEQAGFGGAALVKARYQGEAWARATE
                     QEKRRQGNTTELLVTQVPGERPTVVITTPAIGHVPPRPVLMFSCVDNITRMQVALMHP
                     LDVHDIAVTLNADSRALRSHWFVRENGTLLESSRGLSGIDEIKQLFGAKTLTVDTGTD
                     NAAGKLTFNIDGLARVIAPLRDACHWAGE"
     misc_feature    complement(250217..250789)
                     /locus_tag="ECOK1_0225"
                     /note="type VI secretion-associated protein, VC_A0118
                     family; Region: VI_minor_1; TIGR03360"
                     /db_xref="CDD:132403"
     gene            complement(250945..253704)
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /db_xref="GeneID:12688794"
     CDS             complement(250945..253704)
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /note="identified by match to protein family HMM PF02861;
                     match to protein family HMM PF07724; match to protein
                     family HMM PF07728; match to protein family HMM TIGR03345"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone protein ClpB"
                     /protein_id="YP_006099473.1"
                     /db_xref="GI:386597967"
                     /db_xref="GeneID:12688794"
                     /translation="MIQIDLATLVKRLNPFAKQALEMAASECMSQQASEITVAHVLLQ
                     MLAIPRNDVRVIAERTGISAEDLRQALTVESYPGGRSAEGYPSFSPMLIEWLKESWLL
                     ASAQMQHSELRSGVLLLTLLHSPLRYIPPAAARLLTAINRDQLQQDFAAWTKESAESV
                     DLAGGQTPRATETGDTLLARYAKNMTADARNGRLDPVLCRNYEIDLMIDILCRRRKNN
                     PVVVGEAGVGKSALIEGLALRIVAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEKRF
                     KGLMAEVIFSPVPVILFIDEAHTLIGAGNQQGGLDISNLLKPALARGELKTIAATTWS
                     EYKKYFEKDAALSRRFQLVKVSEPNAAEATIILRGLSAVYEQSHGVLIDDDALQAAAT
                     LSERYLSGRQLPDKAIDVLDTACARVAINLSSPPKQISALTTLSHQQEAEIRQLEREL
                     RIGLRTDTSRMTEVLEQYDETLSALDELEVAWQQQTLVQEIIALRQQLLGVAEDDVAS
                     LPDADAVEDTPPEAEQDSTDAESADDAGSVQPEETAETVSPVQRLAQLTAELDALHND
                     QLLVSPHVDKKQIAAVIAEWTGVPLNRLSQNEMSVITDLPVWLGGTIKGQDLAIASLH
                     KHLLTARADLRRPGRPLGAFLLAGPSGVGKTETVLQLAELLYGGRQYLTTINMSEFQE
                     KHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLFYQAFDKG
                     EMADGEGRLIDCKNIVFFLTSNLGYQVIVEHADDPETMQEALYPVLADFFKPALLARM
                     EVVPYLPLSKETLATIIAGKLARLDNVLRSRFGADVIIGPEVTDEIMSRVTRAENGAR
                     MLESVIDGDMLPPLSLLLLQKMAANTAIARIRLSAADGAFTADVEDALPDDAVTPQTE
                     DETVL"
     misc_feature    complement(251032..253668)
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /note="type VI secretion ATPase, ClpV1 family; Region:
                     VI_ClpV1; TIGR03345"
                     /db_xref="CDD:234172"
     misc_feature    complement(252646..253098)
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(253015..253038)
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(252709..252711,252820..252822,
                     253012..253035))
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(252817..252834)
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(252658..252660)
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(251419..251865)
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(251740..251763)
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(251419..251421,251545..251547,
                     251737..251760))
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(251542..251559)
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(<251107..251289)
                     /gene="clpB"
                     /locus_tag="ECOK1_0226"
                     /note="C-terminal, D2-small domain, of ClpB protein;
                     Region: ClpB_D2-small; cl11083"
                     /db_xref="CDD:264218"
     gene            complement(253714..254478)
                     /locus_tag="ECOK1_0227"
                     /db_xref="GeneID:12688795"
     CDS             complement(253714..254478)
                     /locus_tag="ECOK1_0227"
                     /note="identified by similarity to GB:AAQ96720.1; match to
                     protein family HMM TIGR03349"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099474.1"
                     /db_xref="GI:386597968"
                     /db_xref="GeneID:12688795"
                     /translation="MSDMSEASVFPVEPESGTPGRQYRLALRGNSLNPMIDAATPLLG
                     MVMRLSTMNSQAMPEHLFTQVVTDVQAVEQLLQEQGYEPGVIVSFRYILCTFIDEAAL
                     GNGWSNKNEWIKQSLLVHFHNEAWGGEKVFILLERLIREPVRYQDLLEFLYLCFSLGF
                     RGRYKVAIQQQDEFERIYQRLHHALHKLRGDAPFPLLHQKNNIQGGRYQLIRRLTIKH
                     VLCGGLVVLTVFYLFYLLRLDSQTQDILHQLNKLLR"
     misc_feature    complement(253717..254436)
                     /locus_tag="ECOK1_0227"
                     /note="Type VI protein secretion system component VasF
                     [Intracellular    trafficking, secretion, and vesicular
                     transport]; Region: COG3455"
                     /db_xref="CDD:225986"
     gene            complement(254483..255829)
                     /locus_tag="ECOK1_0228"
                     /db_xref="GeneID:12688796"
     CDS             complement(254483..255829)
                     /locus_tag="ECOK1_0228"
                     /note="identified by similarity to GB:CAH22869.1; match to
                     protein family HMM PF05936; match to protein family HMM
                     TIGR03353"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099475.1"
                     /db_xref="GI:386597969"
                     /db_xref="GeneID:12688796"
                     /translation="MATMKNKVIWQEGLFALPQHFQQQQRHCEYLLTRRLDALGDFFW
                     GFTELSINTELLAQGKIMIDRAAGCMPDGTVFSIPDQDLLPEPFQPGTLSSKESHNIY
                     LALPVISDVINEIQGLHSAGQGTERYRLTHTRVRDFHTDEGDEQPVGLGQLIPRIVSG
                     ADDLSAMVTLPLCRILNKNATGALVLDNTFIPTIQAVRVSGLLGAFSGEVQGLLATRA
                     ADLAGRIGSPEQSGIADVAEFMMLQMLNRYQMQFTHRSQLHTLHPEAFYRDLVGLLGE
                     LMTFTEGNRLPCTVEPYNHRDLTATFTRTVIPELRRALNTVLVPRAQNLPLFFSEGTW
                     IATINDPTLLQSCKLVLAVRARMPYDQVQRQFIQQSKVAATDKIRSVVSVQVPGIPLH
                     TLTAAPRQLPYHEGYVYFELEKGTPAWQDVIKAGALALHISGSFPDLNLQLWAIRG"
     misc_feature    complement(254486..255817)
                     /locus_tag="ECOK1_0228"
                     /note="Predicted component of the type VI protein
                     secretion system [Intracellular trafficking, secretion,
                     and    vesicular transport]; Region: COG3522"
                     /db_xref="CDD:226053"
     gene            complement(255832..256356)
                     /locus_tag="ECOK1_0229"
                     /db_xref="GeneID:12688797"
     CDS             complement(255832..256356)
                     /locus_tag="ECOK1_0229"
                     /note="identified by match to protein family HMM
                     TIGR03352"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion lipoprotein"
                     /protein_id="YP_006099476.1"
                     /db_xref="GI:386597970"
                     /db_xref="GeneID:12688797"
                     /translation="MNGKAFLACVLMSVVLTGCETAKKISQVIRNPDIQVGKLMDQST
                     ELTVTLLTEPDSNLTADGEAAPVDVQLVYLSDDSKFHAADYDQVATTALPDVLGKNYI
                     DHQDFNLLPDTVKTLPPIKLDEKTGYIGVIAYFSDDQATEWKQIESVESIGHHYRLLV
                     HIRASAIEMKKEEN"
     misc_feature    complement(255838..256356)
                     /locus_tag="ECOK1_0229"
                     /note="Predicted component of the type VI protein
                     secretion system [Intracellular trafficking, secretion,
                     and    vesicular transport]; Region: COG3521"
                     /db_xref="CDD:226052"
     gene            complement(256353..257633)
                     /locus_tag="ECOK1_0230"
                     /db_xref="GeneID:12688798"
     CDS             complement(256353..257633)
                     /locus_tag="ECOK1_0230"
                     /note="identified by similarity to GB:CAH22871.1; match to
                     protein family HMM TIGR03354"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099477.1"
                     /db_xref="GI:386597971"
                     /db_xref="GeneID:12688798"
                     /translation="MAEEKQQSRQASLTLQVMNGNELESGRAAKCLFSENGGDIGHTP
                     ECHWQVQDRAGSIAARACTVIRHDGAYCLRCLTPGLMINLAPASSDALIRLRQGDEIQ
                     LGALALKVFLHDGAAVTYDERMATPETIVMNRDSLADTLLTTEGQPAYPGMPFQHQLA
                     PTVAHGFSSDPLQALQTESLMVADDPIAPRVSRPVAPASDLTGANGINTPFMDLPPGN
                     ARHEDGDEFSAMAQYHLAVTPLLRGMECPLTLHNSQDADEFLEEAGRALQAAIKGLLS
                     LQQQQNSLSDKHLRPLEDNPLRLDMDYATALNVMFAEGKSPVHLAAPAAIAESLRNIR
                     HHEEANRAAIVEALRVMLDAFSPGNLMRRFAQYRRSHELRQKMDDAWAWQMYSNYYDE
                     LASSRQQGFEMLFNEVYAQVYDRVLRETQREPEA"
     misc_feature    complement(256380..257597)
                     /locus_tag="ECOK1_0230"
                     /note="type VI secretion system FHA domain protein;
                     Region: VI_FHA; TIGR03354"
                     /db_xref="CDD:234178"
     misc_feature    complement(257322..257516)
                     /locus_tag="ECOK1_0230"
                     /note="Forkhead associated domain (FHA); found in
                     eukaryotic and prokaryotic proteins. Putative nuclear
                     signalling domain. FHA domains may bind phosphothreonine,
                     phosphoserine and sometimes phosphotyrosine. In
                     eukaryotes, many FHA domain-containing proteins...;
                     Region: FHA; cl00062"
                     /db_xref="CDD:260165"
     gene            complement(257650..258699)
                     /locus_tag="ECOK1_0231"
                     /db_xref="GeneID:12688799"
     CDS             complement(257650..258699)
                     /locus_tag="ECOK1_0231"
                     /note="identified by similarity to GB:AAS64100.1; match to
                     protein family HMM PF06996; match to protein family HMM
                     TIGR03347"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099478.1"
                     /db_xref="GI:386597972"
                     /db_xref="GeneID:12688799"
                     /translation="MAGENGPARPDIATKPPLPADVRNCNFYVLMEALYRRHGAPGQD
                     ISLRTEPAREIVRFSSDASISFPGTDLSALSRSQNGQYVLQTRFLGFSGSQSPLPGYY
                     LDQMAQESAQNEDGLKEFLDLFSHRWTQFAYHAWRKYRYYICFRSGGTDTFSQRMYAL
                     VGLGNQSVRDRLAINHSKMLAYAGILATPGRAPEVICNLVSHCFDLPDVTIERWQLRK
                     VAIDPAHQNRLGVRNPKGKTAGHIPGRSILGVNFTLGARVPDRSGKFLLQIGGLSRER
                     YLSFLPDGENHLPLTMFLSFILRDQFAWDLRLCLAPQQAKGMRLSDPASSRLGRTSFI
                     GQPKVPPAITIRIRE"
     misc_feature    complement(257695..258639)
                     /locus_tag="ECOK1_0231"
                     /note="type VI secretion protein, VC_A0111 family; Region:
                     VI_chp_1; TIGR03347"
                     /db_xref="CDD:234174"
     gene            complement(258663..260504)
                     /locus_tag="ECOK1_0232"
                     /db_xref="GeneID:12688800"
     CDS             complement(258663..260504)
                     /locus_tag="ECOK1_0232"
                     /note="identified by match to protein family HMM PF05947;
                     match to protein family HMM TIGR03359"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099479.1"
                     /db_xref="GI:386597973"
                     /db_xref="GeneID:12688800"
                     /translation="MAFEERYYREELDYLRQLGKLLAQEKPHLAHFLAEKEGDPDVER
                     LMEAFAFMSGSLRQKLEDEFPEFTHGLIRMLWANYLRPVPAMTVIAYEPKTDQLKVPV
                     QVCRNELIRSRSEKSSLTAQKVLPDNHDKIVSSVACHFTLARDIWLQPLRILDTRNAS
                     SLKEGIIDISFTADNNVSPAMLDLNKITFWLGNEDDYTRHQLYLWFCECLMDAELIAG
                     EYRLPLPDLWLEAAGFDNRDALLPWPKNVHSGYRVLQEYFCYPEAFFFFHLRDVAPLP
                     DDFPINAFTLRLHFNRPLPADIKLRQDSLRLHCTPAINLFTHYAEPVRPDGRMAEYPL
                     RASHKHPDAYDIFQVSTVTSKVKVSGTEISPGSQARVWPEFESFQHQMEYSRQREVVY
                     WHHRTKTSLLHHGLEHSIAFVHADGSIPGSSRFNDDVITTSLICTNRMIPARLHTGDI
                     CVAVNKNPAVASFRNVTRPTLPLWPVTDGDMHWSLISAMNLNYLSLLDRETLIQILRT
                     FDLPGAHHPQRARLSRQKLDAIEKLETKPVDRLFKGVPVRGLATTLWIRPDPFICEGE
                     IYLLGTVLSHFFALYASINSYHCLKIINTESQESWEWQEKMGQHALI"
     misc_feature    complement(258666..260489)
                     /locus_tag="ECOK1_0232"
                     /note="Bacterial protein of unknown function (DUF879);
                     Region: DUF879; pfam05947"
                     /db_xref="CDD:253471"
     gene            complement(260510..260935)
                     /locus_tag="ECOK1_0233"
                     /db_xref="GeneID:12688801"
     CDS             complement(260510..260935)
                     /locus_tag="ECOK1_0233"
                     /note="identified by similarity to GB:CAH22874.1; match to
                     protein family HMM PF04965; match to protein family HMM
                     TIGR03357"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099480.1"
                     /db_xref="GI:386597974"
                     /db_xref="GeneID:12688801"
                     /translation="MLRRDSGPTGSLFERIREAANPPSYQNPKEALIRSIRRNLRQVL
                     NTRSGSCYGSPELGITDLNDESLASSDFRREIRKSISQCILHYEPRITDVVVTAAAPD
                     EYAPVELCFHIVATVDVSETRGVFEFDILLDNHQRYCVE"
     misc_feature    complement(260516..260911)
                     /locus_tag="ECOK1_0233"
                     /note="type VI secretion system lysozyme-like protein;
                     Region: VI_zyme; TIGR03357"
                     /db_xref="CDD:234181"
     gene            complement(260940..262424)
                     /locus_tag="ECOK1_0234"
                     /db_xref="GeneID:12688802"
     CDS             complement(260940..262424)
                     /locus_tag="ECOK1_0234"
                     /note="identified by similarity to GB:CAC93174.1; match to
                     protein family HMM PF05943; match to protein family HMM
                     TIGR03355"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099481.1"
                     /db_xref="GI:386597975"
                     /db_xref="GeneID:12688802"
                     /translation="MSVKEEIAPVSASQTAAPPSLLDEIMAQTRVQPKSESYDITRQG
                     VSAFIAAMLQGDSSAEPINILAVDAMIADIDARTSRQMDAIIHAPEFQELESLLRSLK
                     LLVERADTRENIKVHFLNVTQEELLDDFEFAPEITQSAYYKHVYSSGYGQFGGEPVAA
                     VIGNFAFKNTTPDMKLLKYISQVSAMAHSPFLSSVSSEFFGLDSWTELPGIKEPGAIF
                     EGPAYSRWRALRESEDSRYLGLTAPRFLLRHPYSPDENPVKTFRYHEDVSQSHESYLW
                     GNTSFLLAANLAESFAKYRWCPNIIGPSSGGAVKDLPVHLYESMGQMQAKIPTEVLIT
                     DRREYELAEEGFITLTMRKGSDNACFFSANSVQKPKTFPKTPEGKAAETNYKLGTQLP
                     YLFVISRLAHYIKVIQREQLGSWKERSDLERELNTWIRQYVADQENPPAEVRSHRPLR
                     QAKIEVLDVDGEPGWYQVAISVRPHFKYMGASFDLSLVGRLDKE"
     misc_feature    complement(260943..262424)
                     /locus_tag="ECOK1_0234"
                     /note="Predicted component of the type VI protein
                     secretion system [Intracellular trafficking, secretion,
                     and    vesicular transport]; Region: COG3517"
                     /db_xref="CDD:226048"
     gene            complement(262447..262950)
                     /locus_tag="ECOK1_0235"
                     /db_xref="GeneID:12688803"
     CDS             complement(262447..262950)
                     /locus_tag="ECOK1_0235"
                     /note="identified by similarity to GB:CAE12667.1; match to
                     protein family HMM PF05591; match to protein family HMM
                     TIGR03358"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099482.1"
                     /db_xref="GI:386597976"
                     /db_xref="GeneID:12688803"
                     /translation="MSKMNNNGGSVAPKERISVRYTPKVDGVAADIELPLNLLITGNL
                     KGKPDNTPLDERTAIAINRYNLNAVISEADIEREFVVPAELSDAPNEQMYVNLKVKSM
                     DDLSPDHIASQVPEIKRLLELREALVALKSPLGNIPAFRAQLQALLENEDTREQLIQE
                     LGIAVQK"
     misc_feature    complement(262459..262932)
                     /locus_tag="ECOK1_0235"
                     /note="type VI secretion protein, VC_A0107 family; Region:
                     VI_chp_5; TIGR03358"
                     /db_xref="CDD:132401"
     gene            263656..264174
                     /locus_tag="ECOK1_0236"
                     /db_xref="GeneID:12688804"
     CDS             263656..264174
                     /locus_tag="ECOK1_0236"
                     /note="identified by similarity to GB:AAQ96710.1; match to
                     protein family HMM PF05638; match to protein family HMM
                     TIGR03344"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099483.1"
                     /db_xref="GI:386597977"
                     /db_xref="GeneID:12688804"
                     /translation="MPTPCYISITGQTQGNITAGAFTADSVGNIYVQGHEDEMLVQEF
                     LHNVTVPTDPQSGQPSGQRAHKPFIFTVALNKAVPLLYNALASGEMLPKVELHWWRTS
                     VEGKQEHYFTTRLTDATIVDMNLHMPHCQDPAQREFTQLLAVSLAYRKVEWEHIKSGT
                     SGADDWRAPLEA"
     misc_feature    263659..264162
                     /locus_tag="ECOK1_0236"
                     /note="type VI secretion system effector, Hcp1 family;
                     Region: VI_effect_Hcp1; TIGR03344"
                     /db_xref="CDD:213799"
     gene            264395..266377
                     /locus_tag="ECOK1_0237"
                     /db_xref="GeneID:12688805"
     CDS             264395..266377
                     /locus_tag="ECOK1_0237"
                     /note="identified by match to protein family HMM PF04524;
                     match to protein family HMM PF06715; match to protein
                     family HMM TIGR01646; match to protein family HMM
                     TIGR03361"
                     /codon_start=1
                     /transl_table=11
                     /product="ImpA family type VI secretion-associated
                     protein"
                     /protein_id="YP_006099484.1"
                     /db_xref="GI:386597978"
                     /db_xref="GeneID:12688805"
                     /translation="MSLKGLRFTLEVDGQEPDTFAVVNFRLIQNQSYPFVMSVDVASD
                     SFMQTAEMLLEKNATLTIWQGVIPLRYVTGVVAGFGMQENNGWQMRYHLRIEPPLWRC
                     GLRRNFRIFQQQDIRTISATLLNENGVTEWTPLFYEDHPAREFCVQYGESDLAFLARL
                     WAEEGIFFFERFAADSPEQKLTLCDDVAGLSQAGELPFNPDTSAGAETECVSMFRYEA
                     HVRPSSVQSQDYTFKVPDWPGMYEQQGESLNGQLEQYEIFDYPGRYKDEQHGKDFTLY
                     RMESLRSDAEKATGQSNSPKLWPGTWFTLTGHPQKMLNREWQVVQSILSGDQPQALHG
                     SQGRGTTLGNQLEVIPADRTWRPRLQSKPKVDGPQSAIVTGPAGEEIFCDEHGRVRVK
                     FHWDRYNPATEASSCWVRVSQAWAGPGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRT
                     YHEDNRSPGSLPGTKTQMTIRSKTYKGSGFNELRFEDATGGEQVYIHAQKNMDTEVLN
                     NRTTDVKADHTETIGNDQKITVGLGQTVNVGSKKEGGHDQKVTVANDQHLTIKNDRHK
                     VVNNNQTSKVTGTDTEEVVKKQSIKIGDNYELKVEHGTNIISGDSIELICGQGESGTC
                     SIKLEKTGKIIIRGTEFLFEATGPVDIKGKDIHLNG"
     misc_feature    264416..265951
                     /locus_tag="ECOK1_0237"
                     /note="type VI secretion system Vgr family protein;
                     Region: VI_Rhs_Vgr; TIGR03361"
                     /db_xref="CDD:234183"
     misc_feature    264494..265384
                     /locus_tag="ECOK1_0237"
                     /note="Phage late control gene D protein (GPD); Region:
                     Phage_GPD; pfam05954"
                     /db_xref="CDD:253474"
     misc_feature    265493..265777
                     /locus_tag="ECOK1_0237"
                     /note="Phage-related baseplate assembly protein; Region:
                     Phage_base_V; pfam04717"
                     /db_xref="CDD:252757"
     misc_feature    265808..>265876
                     /locus_tag="ECOK1_0237"
                     /note="Putative type VI secretion system Rhs element Vgr;
                     Region: T6SS_Vgr; pfam13296"
                     /db_xref="CDD:205476"
     misc_feature    265895..265963
                     /locus_tag="ECOK1_0237"
                     /note="Gp5 C-terminal repeat (3 copies); Region: Gp5_C;
                     pfam06715"
                     /db_xref="CDD:253874"
     gene            266484..267530
                     /locus_tag="ECOK1_0238"
                     /db_xref="GeneID:12688806"
     CDS             266484..267530
                     /locus_tag="ECOK1_0238"
                     /note="identified by similarity to GB:AAL44453.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099485.1"
                     /db_xref="GI:386597979"
                     /db_xref="GeneID:12688806"
                     /translation="MIEMKNNTPFPLLSFEKYGRYGLLFDVIAIKMSLRIKNGFYADL
                     AEFQKELSMSDEYYGESETSSLKSETDLVLCKRNTDIHVTGSAHAPSGDKSQWKACVR
                     VNSFSKELSLSGVRYLQYERNRWQMSLPDKIINVPLRYELAYGGIWQPDGMEKLVFSA
                     NPVGCGYYPDISQLNTSCQYKLPQITSSALSENATIFNGESDFFQGVGPVSRWWKSRL
                     QYAGTYNEVWREKRYPYLPDDFDERFYNSAHPDMIYTGFLSGDENISLEGFFKFEQVV
                     KTKLPGIRPVLILKTKHNTSHMFLPVADTMVIDLSRQEIYLTWRLTIPDFFGMKEGVL
                     SCIIPECIGKKYYG"
     misc_feature    266538..267443
                     /locus_tag="ECOK1_0238"
                     /note="Uncharacterized protein conserved in bacteria
                     (DUF2169); Region: DUF2169; pfam09937"
                     /db_xref="CDD:255647"
     gene            267523..268962
                     /locus_tag="ECOK1_0239"
                     /db_xref="GeneID:12688807"
     CDS             267523..268962
                     /locus_tag="ECOK1_0239"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099486.1"
                     /db_xref="GI:386597980"
                     /db_xref="GeneID:12688807"
                     /translation="MGNYHIGDGECRFRVVCSSPDVCEVGGYKVPFDSYQTLDSERQY
                     SSTVWARGCRALNVGSVIAGTQSNAGKGVISGTSQGTGDCVILTGSPTVTIEGKPVAY
                     HGSVVGINNHNCLGKLYTKIKSPMISVIDRTFNYERTAEVIHDLLLLKDLLSVGNIFD
                     GDISPEVKNDLFQIKDPDQSWGEFFSIKNIRESLRNGIEGDKSQIREWFGENTLTQMG
                     NGAITTLHGVADLALVTFDALLDTATATVACPIGEDGLCEQANINLNEKEQALFNISN
                     SLINGQAWDALKKMIMDTNNGDQIALEHFASFLWGFMIPAKIPEENISGKVFVEPVVL
                     EGGAGGNWTVFDEVLDSNVIKQLTLTGCGAACGEMLLRDRYIFVTQNVIGTELTSMTS
                     LANKLNKFDVGWEGNAVSESSLYALSNTGSWGAMMWDSGSKVGHWVLVKGVDDAGNVI
                     IYDPYQGSRYLMTEQEFKEVWNGHSVYKP"
     misc_feature    267559..267873
                     /locus_tag="ECOK1_0239"
                     /note="Domain of unknown function (DUF4150); Region:
                     DUF4150; pfam13665"
                     /db_xref="CDD:257972"
     misc_feature    268588..268953
                     /locus_tag="ECOK1_0239"
                     /note="Peptidase family C39 mostly contains
                     bacteriocin-processing endopeptidases from bacteria. The
                     cysteine peptidases in family C39 cleave the
                     'double-glycine' leader peptides from the precursors of
                     various bacteriocins (mostly non-lantibiotic); Region:
                     Peptidase_C39_like; cd02259"
                     /db_xref="CDD:239073"
     misc_feature    order(268588..268590,268606..268608,268828..268830,
                     268879..268881)
                     /locus_tag="ECOK1_0239"
                     /note="putative active site [active]"
                     /db_xref="CDD:239073"
     gene            269485..270249
                     /locus_tag="ECOK1_0240"
                     /note="ISEc1, transposase, degenerate; this region
                     contains one or more premature stops and/or frameshifts"
                     /pseudo
                     /db_xref="GeneID:12688808"
     gene            271075..271563
                     /locus_tag="ECOK1_0241"
                     /db_xref="GeneID:12688809"
     CDS             271075..271563
                     /locus_tag="ECOK1_0241"
                     /note="identified by similarity to GB:AAY36505.1; match to
                     protein family HMM TIGR03765"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099487.1"
                     /db_xref="GI:386597981"
                     /db_xref="GeneID:12688809"
                     /translation="MLKMSLYVIILLFSLQFSAAITGKESEVVSPLLMDVNPSLTMEN
                     ISELSTSSEPSQQGVFPVICTRLHPGSVMKRQLLTGWGPVFIIGDDPFSLRWMSEHLE
                     ILKSLNALGLVVNVESVERMEVLQQRADGLLLLPVICDNFVQALQLNAYPVLITEMEI
                     SQ"
     misc_feature    271135..271557
                     /locus_tag="ECOK1_0241"
                     /note="Protein of unknown function (DUF2859); Region:
                     DUF2859; pfam11072"
                     /db_xref="CDD:256276"
     gene            complement(271834..272604)
                     /locus_tag="ECOK1_0242"
                     /db_xref="GeneID:12688810"
     CDS             complement(271834..272604)
                     /locus_tag="ECOK1_0242"
                     /note="identified by match to protein family HMM PF00795"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="YP_006099488.1"
                     /db_xref="GI:386597982"
                     /db_xref="GeneID:12688810"
                     /translation="MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMF
                     TSGFAMEAAASSLAQDDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTV
                     HFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAL
                     YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIA
                     TADAHQATRIDAELSMMALREYREKFPAWRDADEFRLW"
     misc_feature    complement(271846..272595)
                     /locus_tag="ECOK1_0242"
                     /note="Xanthomonas campestris XC1258 and related proteins,
                     members of the nitrilase superfamily (putative class 13
                     nitrilases); Region: Xc-1258_like; cd07575"
                     /db_xref="CDD:143599"
     misc_feature    complement(order(272110..272115,272170..272175,
                     272179..272184,272257..272259,272272..272274,
                     272284..272286,272461..272463,272479..272481))
                     /locus_tag="ECOK1_0242"
                     /note="putative active site [active]"
                     /db_xref="CDD:143599"
     misc_feature    complement(order(272182..272184,272284..272286,
                     272479..272481))
                     /locus_tag="ECOK1_0242"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:143599"
     misc_feature    complement(order(271846..271863,271867..271878,
                     271915..271917,271921..271926,271930..271932,
                     271942..271968,271972..271974,272056..272061,
                     272065..272073,272077..272082,272089..272094,
                     272152..272154,272158..272172,272179..272181,
                     272266..272268,272278..272283))
                     /locus_tag="ECOK1_0242"
                     /note="multimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:143599"
     misc_feature    complement(order(271846..271863,271867..271878,
                     271960..271968,272056..272061,272065..272073,
                     272077..272082,272089..272094,272152..272154,
                     272158..272172,272179..272181,272266..272268,
                     272278..272283))
                     /locus_tag="ECOK1_0242"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143599"
     gene            272758..273231
                     /locus_tag="ECOK1_0243"
                     /db_xref="GeneID:12688811"
     CDS             272758..273231
                     /locus_tag="ECOK1_0243"
                     /note="identified by similarity to SP:P0AD59; similarity
                     to SP:P45502; match to protein family HMM PF08816"
                     /codon_start=1
                     /transl_table=11
                     /product="inhibitor of vertebrate lysozyme"
                     /protein_id="YP_006099489.1"
                     /db_xref="GI:386597983"
                     /db_xref="GeneID:12688811"
                     /translation="MGRISPGGMMFKAITTVAALVIATSAMAQDDLTISSLAKGETTK
                     AAFNQMVQGHKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEK
                     SNQMTGLFSTIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK"
     misc_feature    272770..273228
                     /locus_tag="ECOK1_0243"
                     /note="C-lysozyme inhibitor; Provisional; Region:
                     PRK09993"
                     /db_xref="CDD:182187"
     gene            complement(273274..275718)
                     /gene="fadE"
                     /locus_tag="ECOK1_0244"
                     /db_xref="GeneID:12688812"
     CDS             complement(273274..275718)
                     /gene="fadE"
                     /locus_tag="ECOK1_0244"
                     /EC_number="1.3.99.-"
                     /note="identified by similarity to SP:Q8ZRJ7; match to
                     protein family HMM PF00441; match to protein family HMM
                     PF09317"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-coenzyme A dehydrogenase"
                     /protein_id="YP_006099490.1"
                     /db_xref="GI:386597984"
                     /db_xref="GeneID:12688812"
                     /translation="MMILSILATVVLLSALFYHRVSLFISSLILLAWTAALGVAGLWS
                     AWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     DEQKNHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVMGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVP
                     FQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAYIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSST
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAV
                     LKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRH
                     YLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQ
                     RICKELGKNLPFTRLDELAHNALAKGLIDKDEAAILVKAEESRLRSINVDDFDPEELA
                     TKPVKLPEKVRKVEAA"
     misc_feature    complement(273277..275595)
                     /gene="fadE"
                     /locus_tag="ECOK1_0244"
                     /note="acyl-CoA dehydrogenase; Reviewed; Region: fadE;
                     PRK09463"
                     /db_xref="CDD:236528"
     misc_feature    complement(274219..275265)
                     /gene="fadE"
                     /locus_tag="ECOK1_0244"
                     /note="Acyl-CoA dehydrogenase; Region: ACAD; cl09933"
                     /db_xref="CDD:263927"
     misc_feature    complement(order(274222..274224,274228..274236,
                     274876..274878,274882..274884,274999..275001,
                     275005..275007,275098..275100))
                     /gene="fadE"
                     /locus_tag="ECOK1_0244"
                     /note="active site"
                     /db_xref="CDD:173838"
     misc_feature    complement(273343..274179)
                     /gene="fadE"
                     /locus_tag="ECOK1_0244"
                     /note="Domain of unknown function (DUF1974); Region:
                     DUF1974; pfam09317"
                     /db_xref="CDD:255283"
     gene            275958..276536
                     /gene="gmhA"
                     /locus_tag="ECOK1_0245"
                     /db_xref="GeneID:12688813"
     CDS             275958..276536
                     /gene="gmhA"
                     /locus_tag="ECOK1_0245"
                     /EC_number="5.3.1.-"
                     /note="identified by match to protein family HMM
                     TIGR00441"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoheptose isomerase"
                     /protein_id="YP_006099491.1"
                     /db_xref="GI:386597985"
                     /db_xref="GeneID:12688813"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFS
                     RYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     misc_feature    275985..276521
                     /gene="gmhA"
                     /locus_tag="ECOK1_0245"
                     /note="Phosphoheptose isomerase is a member of the SIS
                     (Sugar ISomerase) superfamily. Phosphoheptose isomerase
                     catalyzes the isomerization of sedoheptulose 7-phosphate
                     into D-glycero-D-mannoheptose 7-phosphate. This is the
                     first step of the biosynthesis of...; Region: SIS_GmhA;
                     cd05006"
                     /db_xref="CDD:240139"
     misc_feature    order(275994..275996,276006..276008,276048..276050,
                     276057..276059,276117..276119,276135..276140,
                     276471..276476,276486..276488,276495..276497,
                     276507..276509,276519..276521)
                     /gene="gmhA"
                     /locus_tag="ECOK1_0245"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:240139"
     misc_feature    order(276111..276119,276312..276320,276327..276329,
                     276456..276458,276471..276473)
                     /gene="gmhA"
                     /locus_tag="ECOK1_0245"
                     /note="active site"
                     /db_xref="CDD:240139"
     gene            276741..277508
                     /locus_tag="ECOK1_0247"
                     /db_xref="GeneID:12688814"
     CDS             276741..277508
                     /locus_tag="ECOK1_0247"
                     /note="identified by match to protein family HMM PF00310"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glutamine amidotransferase, class-II"
                     /protein_id="YP_006099492.1"
                     /db_xref="GI:386597986"
                     /db_xref="GeneID:12688814"
                     /translation="MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSFNSPIAKLVQDYPIKSCSVLAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIA
                     SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGECVV"
     misc_feature    276741..277493
                     /locus_tag="ECOK1_0247"
                     /note="Glutamine amidotransferases class-II
                     (Gn-AT)_YafJ-type.  YafJ is a glutamine
                     amidotransferase-like protein of unknown function found in
                     prokaryotes, eukaryotes and archaea.  YafJ has a conserved
                     structural fold similar to those of other class II...;
                     Region: YafJ; cd01908"
                     /db_xref="CDD:238889"
     misc_feature    order(276744..276746,276975..276977,277062..277070,
                     277125..277127)
                     /locus_tag="ECOK1_0247"
                     /note="putative active site [active]"
                     /db_xref="CDD:238889"
     misc_feature    276762..277391
                     /locus_tag="ECOK1_0247"
                     /note="Glutamine amidotransferases class-II; Region:
                     GATase_2; pfam00310"
                     /db_xref="CDD:249761"
     misc_feature    order(276879..276881,276888..276893,277026..277028,
                     277098..277103,277164..277166)
                     /locus_tag="ECOK1_0247"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238889"
     gene            complement(277479..278219)
                     /locus_tag="ECOK1_0246"
                     /db_xref="GeneID:12688815"
     CDS             complement(277479..278219)
                     /locus_tag="ECOK1_0246"
                     /note="identified by match to protein family HMM PF06104"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099493.1"
                     /db_xref="GI:386597987"
                     /db_xref="GeneID:12688815"
                     /translation="MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQ
                     LKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
                     ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVN
                     GRYVVSKPLSHEVVQPQLASNYTLPEAK"
     misc_feature    complement(277482..278219)
                     /locus_tag="ECOK1_0246"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3034"
                     /db_xref="CDD:225577"
     gene            complement(278476..278616)
                     /locus_tag="ECOK1_0248"
                     /db_xref="GeneID:12688816"
     CDS             complement(278476..278616)
                     /locus_tag="ECOK1_0248"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099494.1"
                     /db_xref="GI:386597988"
                     /db_xref="GeneID:12688816"
                     /translation="MVALASKGSKTHNENTPGCRNLPCKNEDMKDINQLNEGENFKRP
                     EE"
     gene            278543..279280
                     /locus_tag="ECOK1_0249"
                     /db_xref="GeneID:12688817"
     CDS             278543..279280
                     /locus_tag="ECOK1_0249"
                     /note="identified by match to protein family HMM PF00877"
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="YP_006099495.1"
                     /db_xref="GI:386597989"
                     /db_xref="GeneID:12688817"
                     /translation="MHGRFLHPGVFSLCVLLPLLASATTSHISFSYAARQRMQNRARL
                     LKQYQTHLKKQASYIVEGNAKSRRALRQHNREQIKQHPEWFPAPLKASDRRWQALVEN
                     NHFLSSDHLHNITEVAIHRLEQQLGKPYIWGGTRPDKGFDCSGLVFYAYNKILEAKLP
                     RTANEMYHYRRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDGQFIESPRTGETI
                     RVSRLAEPFWQDHFLGARRILTEETIL"
     misc_feature    <278831..279250
                     /locus_tag="ECOK1_0249"
                     /note="Cell wall-associated hydrolases
                     (invasion-associated proteins) [Cell envelope biogenesis,
                     outer membrane]; Region: Spr; COG0791"
                     /db_xref="CDD:223862"
     misc_feature    278921..279253
                     /locus_tag="ECOK1_0249"
                     /note="NlpC/P60 family; Region: NLPC_P60; pfam00877"
                     /db_xref="CDD:189752"
     gene            279456..279953
                     /locus_tag="ECOK1_0250"
                     /db_xref="GeneID:12688818"
     CDS             279456..279953
                     /locus_tag="ECOK1_0250"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099496.1"
                     /db_xref="GI:386597990"
                     /db_xref="GeneID:12688818"
                     /translation="MSEYRRYYIKGGTWFFTVNLQNRRNQLLTTQFQTLRNVIIKVKR
                     DRPFEINAWVVLPEHMHCIWTLPEGDDDFSSRWREIKKQFTHACGLKNIWQPRFWEHA
                     IRNTKDYRHHVDYIYINPVKHGWVKQVSDWPFSTFHRDVAKGLYPIDWAGDVTDFSAG
                     ERIIL"
     misc_feature    279456..279860
                     /locus_tag="ECOK1_0250"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG1943"
                     /db_xref="CDD:224854"
     gene            complement(280036..280194)
                     /locus_tag="ECOK1_0251"
                     /db_xref="GeneID:12688819"
     CDS             complement(280036..280194)
                     /locus_tag="ECOK1_0251"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099497.1"
                     /db_xref="GI:386597991"
                     /db_xref="GeneID:12688819"
                     /translation="MIRRVAAHLAPVHNRRMRRERLIRPTGECGFVGMIRRICVASGT
                     GAQPPDAA"
     gene            complement(280273..282012)
                     /gene="fhiA"
                     /locus_tag="ECOK1_0252"
                     /db_xref="GeneID:12688820"
     CDS             complement(280273..282012)
                     /gene="fhiA"
                     /locus_tag="ECOK1_0252"
                     /note="identified by match to protein family HMM PF00771"
                     /codon_start=1
                     /transl_table=11
                     /product="protein FhiA"
                     /protein_id="YP_006099498.1"
                     /db_xref="GI:386597992"
                     /db_xref="GeneID:12688820"
                     /translation="MLSRSDLLTLLTINFIVVTKGAERISEVSARFTLDAMPGKQMAI
                     DADLNAGLINQTQAQTRRKDVASEADFYGAMDGASKFVRGDAIAGMMILAINLIGGVC
                     IGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDVRN
                     QLLASPSVLYTATGIMFVLAVVPGMPHFPFLMFSALLGFTGWRMSKRPQAAEAEEKSL
                     ETLTRTMTETSEQQVSWETIPLIEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVIS
                     DGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMALPSSETYGEIDGVL
                     GNDPAYGMPVTWIQPAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFNYDDITQ
                     LHNRLSSMAPRLAEDLSAALNYSQLLKVYRTLLTEGVSLRDIVTIATVLVASSAVTKD
                     HILLAADVRLVLRRSITHPFVRKQELTVYTLNNELENLLTNVVNQAQQAGKVMLDSVP
                     VDPNMLNQFQITMPQVKEQMKAAGKDPVLLVPPQLRPLLARYARLFAPGLHVLSYNEV
                     LDELELKIMGALM"
     misc_feature    complement(280279..281991)
                     /gene="fhiA"
                     /locus_tag="ECOK1_0252"
                     /note="Flagellar biosynthesis pathway, component FlhA
                     [Cell motility and secretion / Intracellular trafficking
                     and secretion]; Region: FlhA; COG1298"
                     /db_xref="CDD:224217"
     gene            281972..282742
                     /locus_tag="ECOK1_0253"
                     /db_xref="GeneID:12688821"
     CDS             281972..282742
                     /locus_tag="ECOK1_0253"
                     /note="identified by similarity to GB:AAN78859.1; match to
                     protein family HMM PF00691"
                     /codon_start=1
                     /transl_table=11
                     /product="putative chemotaxis protein"
                     /protein_id="YP_006099499.1"
                     /db_xref="GI:386597993"
                     /db_xref="GeneID:12688821"
                     /translation="MIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSHLPKPA
                     TVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQG
                     LRVLIKDDQNRNMFERGSAKIMPFFKTLLVELAPVLDSLDNKIIITGHTDAMAYKNNI
                     YNNWNLSGDRALSARRVLEEAGMPENKVMQVSAMADQMLLDAKNPQSAGNRRIEIMVL
                     TKSASDTLYQYFGQHGDKVVQPLVQKLDKQQVLSQRAR"
     misc_feature    281975..282718
                     /locus_tag="ECOK1_0253"
                     /note="hypothetical protein; Validated; Region: PRK06778"
                     /db_xref="CDD:235860"
     misc_feature    282317..282622
                     /locus_tag="ECOK1_0253"
                     /note="Peptidoglycan binding domains similar to the
                     C-terminal domain of outer-membrane protein OmpA; Region:
                     OmpA_C-like; cd07185"
                     /db_xref="CDD:143586"
     misc_feature    order(282323..282328,282422..282427,282434..282436,
                     282455..282460,282467..282469,282602..282604)
                     /locus_tag="ECOK1_0253"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:143586"
     gene            282813..283868
                     /gene="dinB"
                     /locus_tag="ECOK1_0254"
                     /db_xref="GeneID:12688822"
     CDS             282813..283868
                     /gene="dinB"
                     /locus_tag="ECOK1_0254"
                     /EC_number="2.7.7.7"
                     /note="identified by similarity to SP:Q47155; match to
                     protein family HMM PF00817"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="YP_006099500.1"
                     /db_xref="GI:386597994"
                     /db_xref="GeneID:12688822"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
                     DEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNG
                     QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVTLLKRFGKF
                     GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAK
                     VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKSDLIATARKTWDERRGGRGVRLVGL
                     HVTLLDPQMERQLVLGL"
     misc_feature    282825..283829
                     /gene="dinB"
                     /locus_tag="ECOK1_0254"
                     /note="DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa;
                     cd03586"
                     /db_xref="CDD:176459"
     misc_feature    order(282834..282839,282843..282851,282936..282941,
                     282948..282950,282957..282959,283119..283121,
                     283281..283283)
                     /gene="dinB"
                     /locus_tag="ECOK1_0254"
                     /note="active site"
                     /db_xref="CDD:176459"
     misc_feature    282837..283865
                     /gene="dinB"
                     /locus_tag="ECOK1_0254"
                     /note="DNA polymerase IV; Validated; Region: PRK02406"
                     /db_xref="CDD:235035"
     misc_feature    order(282909..282911,282984..282986,283113..283115,
                     283119..283124,283260..283262,283356..283376,
                     283461..283466,283533..283556,283629..283631,
                     283704..283715,283800..283805,283815..283817,
                     283824..283826)
                     /gene="dinB"
                     /locus_tag="ECOK1_0254"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:176459"
     gene            283920..284213
                     /locus_tag="ECOK1_0255"
                     /db_xref="GeneID:12688823"
     CDS             283920..284213
                     /locus_tag="ECOK1_0255"
                     /note="identified by match to protein family HMM PF02604;
                     match to protein family HMM TIGR01552"
                     /codon_start=1
                     /transl_table=11
                     /product="prevent-host-death family protein"
                     /protein_id="YP_006099501.1"
                     /db_xref="GI:386597995"
                     /db_xref="GeneID:12688823"
                     /translation="MHRILAEKSVNITELRKNPAKYFIDQPVAVLSNNRPAGYLLSAS
                     AFEALMDMLAEQEEKKPIKARFRPSAARLEEITRRAEQYLNDMTDDDFNDFKE"
     misc_feature    283920..284210
                     /locus_tag="ECOK1_0255"
                     /note="putative antitoxin of the YafO-YafN toxin-antitoxin
                     system; Provisional; Region: PRK09778"
                     /db_xref="CDD:170091"
     gene            284216..284614
                     /locus_tag="ECOK1_0256"
                     /db_xref="GeneID:12688824"
     CDS             284216..284614
                     /locus_tag="ECOK1_0256"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099502.1"
                     /db_xref="GI:386597996"
                     /db_xref="GeneID:12688824"
                     /translation="MRVFKTKLIRLQLTAEELEALTADFISYKRDGVLPDIFGRDALY
                     DDSFTWPLIKFERVAHIHLANVNNPFPPQLRQFSRTNDAAHLVYCQGAFDEQAWLLIA
                     ILKPEPHKLARDNNQMHKIGKMAEAFRMRF"
     misc_feature    284216..284611
                     /locus_tag="ECOK1_0256"
                     /note="putative toxin YafO; Provisional; Region: PRK09885"
                     /db_xref="CDD:236631"
     gene            284624..285076
                     /locus_tag="ECOK1_0257"
                     /db_xref="GeneID:12688825"
     CDS             284624..285076
                     /locus_tag="ECOK1_0257"
                     /note="identified by match to protein family HMM PF00583"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="YP_006099503.1"
                     /db_xref="GI:386597997"
                     /db_xref="GeneID:12688825"
                     /translation="MNNIQIRNYQPGDFQQLCAIFLRAVTMTASQHYSPQQIAAWAQI
                     DESRWKEKLAKSQVRVAVINAQPVGFITCIGHYIDMLFVEPEYTRRGVASALLKPLIK
                     SESELTVDASITAKPFFERYGFQTVKQQRVECRGTWFTNFYMRYKPQH"
     misc_feature    284660..284995
                     /locus_tag="ECOK1_0257"
                     /note="Acetyltransferase (GNAT) domain; Region:
                     Acetyltransf_10; pfam13673"
                     /db_xref="CDD:257979"
     misc_feature    284801..>284929
                     /locus_tag="ECOK1_0257"
                     /note="N-Acyltransferase superfamily: Various enzymes that
                     characteristically catalyze the transfer of an acyl group
                     to a substrate; Region: NAT_SF; cd04301"
                     /db_xref="CDD:173926"
     misc_feature    order(284864..284872,284900..284905)
                     /locus_tag="ECOK1_0257"
                     /note="Coenzyme A binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173926"
     gene            285254..286405
                     /locus_tag="ECOK1_0258"
                     /db_xref="GeneID:12688826"
     CDS             285254..286405
                     /locus_tag="ECOK1_0258"
                     /note="identified by match to protein family HMM PF01139;
                     match to protein family HMM TIGR03073"
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB protein"
                     /protein_id="YP_006099504.1"
                     /db_xref="GI:386597998"
                     /db_xref="GeneID:12688826"
                     /translation="MEWYMGKYIRPLSDAVFTIASDDLWIESSAIQQLHTTANLPNMQ
                     RVVGMPDLHPGRGYPIGAAFFSVGRFYPALVGNDIGCGMALWQTDILARKYNADKFEK
                     RLSDLDDVAEESWLEENLPSAFAQHPWRNSLGSIGGGNHFAELQQIDQIIDAELFALA
                     GLDAQHLQLLVHSGSRGLGQSILQRHIASFSHHGLPEGSDDALRYIAEHDDALAFARI
                     NRQLIALRIMQQVKATGSPVLDVAHNFVSACQIGDQQGWLHRKGATPDDNGLVIIPGS
                     RGDYSWLVKPVANEKTLHSLAHGAGRKWGRTECKGRLAAKYTATQLSRTELGSRVICR
                     DKQLIFEEAPQAYKSAESVVQCLVLAGLIIPVARLRPVLTLKNSGGKKG"
     misc_feature    285266..286393
                     /locus_tag="ECOK1_0258"
                     /note="hypothetical protein; Reviewed; Region: PRK09588"
                     /db_xref="CDD:181972"
     misc_feature    285308..286381
                     /locus_tag="ECOK1_0258"
                     /note="tRNA-splicing ligase RtcB; Region: RtcB; pfam01139"
                     /db_xref="CDD:250393"
     gene            286402..287016
                     /locus_tag="ECOK1_0259"
                     /db_xref="GeneID:12688827"
     CDS             286402..287016
                     /locus_tag="ECOK1_0259"
                     /note="identified by match to protein family HMM PF00472;
                     match to protein family HMM TIGR03072"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-tRNA hydrolase domain-containing
                     protein"
                     /protein_id="YP_006099505.1"
                     /db_xref="GI:386597999"
                     /db_xref="GeneID:12688827"
                     /translation="MILLQLSSAQGPEECCLAVKKALDRLIKEATRQDVAVTVLETET
                     GRYSDTLRSALISLDGDNAWALSESWCGTIQWICPSPYRPHHGRKNWFLGIGRFTADE
                     QEQSDAIRYETLRSSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLL
                     IAWKLEQQQQENSAALKSQRRMFHHQIERGNPRRTFTGMAFIEG"
     misc_feature    286402..287001
                     /locus_tag="ECOK1_0259"
                     /note="peptide chain release factor-like protein;
                     Reviewed; Region: prfH; PRK08179"
                     /db_xref="CDD:181271"
     misc_feature    286405..287004
                     /locus_tag="ECOK1_0259"
                     /note="putative peptide chain release factor H; Region:
                     release_prfH; TIGR03072"
                     /db_xref="CDD:213768"
     gene            complement(287073..288530)
                     /gene="pepD"
                     /locus_tag="ECOK1_0260"
                     /db_xref="GeneID:12688828"
     CDS             complement(287073..288530)
                     /gene="pepD"
                     /locus_tag="ECOK1_0260"
                     /note="identified by similarity to SP:P15288; match to
                     protein family HMM PF01546; match to protein family HMM
                     PF07687; match to protein family HMM TIGR01893"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="YP_006099506.1"
                     /db_xref="GI:386598000"
                     /db_xref="GeneID:12688828"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDAL
                     KSLVDTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     misc_feature    complement(287085..288512)
                     /gene="pepD"
                     /locus_tag="ECOK1_0260"
                     /note="Xaa-His dipeptidase; Region: aa-his-dipept;
                     TIGR01893"
                     /db_xref="CDD:233622"
     misc_feature    complement(287085..288506)
                     /gene="pepD"
                     /locus_tag="ECOK1_0260"
                     /note="M20 Peptidase D has specificity for
                     beta-alanyl-L-histidine dipeptide; Region: M20_pepD;
                     cd03890"
                     /db_xref="CDD:193510"
     misc_feature    complement(order(287160..287162,288024..288026,
                     288093..288098,288186..288188,288303..288305))
                     /gene="pepD"
                     /locus_tag="ECOK1_0260"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:193510"
     misc_feature    complement(order(287385..287390,287397..287402,
                     287409..287411,287520..287525,287532..287534,
                     287553..287558,287562..287567,287661..287663,
                     287673..287675,287832..287834,287862..287864))
                     /gene="pepD"
                     /locus_tag="ECOK1_0260"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:193510"
     gene            288791..289249
                     /gene="gpt"
                     /locus_tag="ECOK1_0261"
                     /db_xref="GeneID:12688829"
     CDS             288791..289249
                     /gene="gpt"
                     /locus_tag="ECOK1_0261"
                     /EC_number="2.4.2.22"
                     /note="identified by similarity to SP:P0A9M5; match to
                     protein family HMM PF00156"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine-guanine phosphoribosyltransferase"
                     /protein_id="YP_006099507.1"
                     /db_xref="GI:386598001"
                     /db_xref="GeneID:12688829"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFITIFAKPAGRPLVDDYVVDIPQNTWIEQPWDMGVVFVPPISGR"
     misc_feature    288884..289177
                     /gene="gpt"
                     /locus_tag="ECOK1_0261"
                     /note="Phosphoribosyl transferase (PRT)-type I domain;
                     Region: PRTases_typeI; cd06223"
                     /db_xref="CDD:206754"
     misc_feature    order(288896..288898,288902..288904,289052..289060,
                     289064..289078,289133..289135)
                     /gene="gpt"
                     /locus_tag="ECOK1_0261"
                     /note="active site"
                     /db_xref="CDD:206754"
     gene            289341..290585
                     /gene="frsA"
                     /locus_tag="ECOK1_0262"
                     /db_xref="GeneID:12688830"
     CDS             289341..290585
                     /gene="frsA"
                     /locus_tag="ECOK1_0262"
                     /note="identified by similarity to SP:P04335; match to
                     protein family HMM PF06500"
                     /codon_start=1
                     /transl_table=11
                     /product="fermentation-respiration switch protein"
                     /protein_id="YP_006099508.1"
                     /db_xref="GI:386598002"
                     /db_xref="GeneID:12688830"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFSHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     misc_feature    289341..290582
                     /gene="frsA"
                     /locus_tag="ECOK1_0262"
                     /note="Alpha/beta hydrolase of unknown function (DUF1100);
                     Region: DUF1100; pfam06500"
                     /db_xref="CDD:115172"
     misc_feature    289341..290582
                     /gene="frsA"
                     /locus_tag="ECOK1_0262"
                     /note="fermentation/respiration switch protein; Reviewed;
                     Region: frsA; PRK05077"
                     /db_xref="CDD:235337"
     gene            290643..291044
                     /gene="crl"
                     /locus_tag="ECOK1_0263"
                     /db_xref="GeneID:12688831"
     CDS             290643..291044
                     /gene="crl"
                     /locus_tag="ECOK1_0263"
                     /note="identified by similarity to SP:P24251; match to
                     protein family HMM PF07417"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="YP_006099509.1"
                     /db_xref="GI:386598003"
                     /db_xref="GeneID:12688831"
                     /translation="MTLPSGHPKSRLVKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWTSVQIKDAEVVERLEHTLRE
                     FHEKLRELLATLNLKLEPADDFRDEPVKLTA"
     misc_feature    290643..291023
                     /gene="crl"
                     /locus_tag="ECOK1_0263"
                     /note="DNA-binding transcriptional regulator Crl;
                     Provisional; Region: PRK10984"
                     /db_xref="CDD:182882"
     gene            complement(291154..292209)
                     /gene="phoE"
                     /locus_tag="ECOK1_0264"
                     /db_xref="GeneID:12688832"
     CDS             complement(291154..292209)
                     /gene="phoE"
                     /locus_tag="ECOK1_0264"
                     /note="identified by similarity to SP:P02932; match to
                     protein family HMM PF00267"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane pore protein E"
                     /protein_id="YP_006099510.1"
                     /db_xref="GI:386598004"
                     /db_xref="GeneID:12688832"
                     /translation="MKKSTLALVVMGIVASVSVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNDSKDGDQSYIRFGFKGETQINVQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPISGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYVDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAVGMTYQF"
     misc_feature    complement(291157..292122)
                     /gene="phoE"
                     /locus_tag="ECOK1_0264"
                     /note="Porins form aqueous channels for the diffusion of
                     small hydrophillic molecules across the outer membrane.
                     Individual 16-strand anti-parallel beta-barrels form a
                     central pore, and trimerizes thru mainly hydrophobic
                     interactions at the interface. Trimers...; Region:
                     gram_neg_porins; cd00342"
                     /db_xref="CDD:238208"
     misc_feature    complement(order(291157..291159,291163..291165,
                     291169..291171,291256..291258,291265..291270,
                     291760..291765,291769..291771,291868..291876,
                     291904..291918,291922..291927,291958..291969,
                     291973..291975,291979..291987,291991..291993,
                     292009..292023,292084..292092,292096..292098,
                     292114..292116,292120..292122))
                     /gene="phoE"
                     /locus_tag="ECOK1_0264"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238208"
     misc_feature    complement(order(291769..291771,291829..291831,
                     291922..291924,292036..292038,292099..292101))
                     /gene="phoE"
                     /locus_tag="ECOK1_0264"
                     /note="eyelet of channel; other site"
                     /db_xref="CDD:238208"
     gene            292498..293601
                     /gene="proB"
                     /locus_tag="ECOK1_0265"
                     /db_xref="GeneID:12688833"
     CDS             292498..293601
                     /gene="proB"
                     /locus_tag="ECOK1_0265"
                     /EC_number="2.7.2.11"
                     /note="identified by match to protein family HMM PF00696;
                     match to protein family HMM PF01472; match to protein
                     family HMM TIGR01027"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="YP_006099511.1"
                     /db_xref="GI:386598005"
                     /db_xref="GeneID:12688833"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     misc_feature    292498..293592
                     /gene="proB"
                     /locus_tag="ECOK1_0265"
                     /note="gamma-glutamyl kinase; Provisional; Region:
                     PRK05429"
                     /db_xref="CDD:235460"
     misc_feature    292513..293265
                     /gene="proB"
                     /locus_tag="ECOK1_0265"
                     /note="AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes
                     glutamate-dependent ATP cleavage; G5K transfers the
                     terminal phosphoryl group of ATP to the gamma-carboxyl
                     group of glutamate, in the first and controlling step of
                     proline (and, in mammals, ornithine)...; Region:
                     AAK_G5K_ProB; cd04242"
                     /db_xref="CDD:239775"
     misc_feature    order(292537..292539,293002..293010,293017..293022,
                     293128..293130,293134..293136,293146..293148)
                     /gene="proB"
                     /locus_tag="ECOK1_0265"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239775"
     misc_feature    order(292612..292617,292624..292626,292714..292716,
                     292726..292728,292795..292797,292801..292803,
                     292843..292848,292864..292866,292873..292875,
                     292903..292905,292909..292914)
                     /gene="proB"
                     /locus_tag="ECOK1_0265"
                     /note="homotetrameric interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239775"
     misc_feature    292648..292671
                     /gene="proB"
                     /locus_tag="ECOK1_0265"
                     /note="putative phosphate binding site [ion binding];
                     other site"
                     /db_xref="CDD:239775"
     misc_feature    order(292651..292653,292906..292908,292939..292941)
                     /gene="proB"
                     /locus_tag="ECOK1_0265"
                     /note="putative allosteric binding site; other site"
                     /db_xref="CDD:239775"
     misc_feature    293323..293547
                     /gene="proB"
                     /locus_tag="ECOK1_0265"
                     /note="PUA domain; Region: PUA; pfam01472"
                     /db_xref="CDD:250644"
     gene            293613..294866
                     /gene="proA"
                     /locus_tag="ECOK1_0266"
                     /db_xref="GeneID:12688834"
     CDS             293613..294866
                     /gene="proA"
                     /locus_tag="ECOK1_0266"
                     /EC_number="1.2.1.41"
                     /note="identified by match to protein family HMM PF00171;
                     match to protein family HMM TIGR00407"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl phosphate reductase"
                     /protein_id="YP_006099512.1"
                     /db_xref="GI:386598006"
                     /db_xref="GeneID:12688834"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSESILN
                     ANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
                     DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
                     MAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
     misc_feature    293619..294848
                     /gene="proA"
                     /locus_tag="ECOK1_0266"
                     /note="Gamma-glutamyl phosphate reductase (GPR), aldehyde
                     dehydrogenase families 18 and 19; Region:
                     ALDH_F18-19_ProA-GPR; cd07079"
                     /db_xref="CDD:143398"
     misc_feature    294369..294371
                     /gene="proA"
                     /locus_tag="ECOK1_0266"
                     /note="putative catalytic cysteine [active]"
                     /db_xref="CDD:143398"
     gene            294981..295056
                     /locus_tag="ECOK1_0267"
                     /db_xref="GeneID:12688835"
     tRNA            294981..295056
                     /locus_tag="ECOK1_0267"
                     /product="tRNA-Thr"
                     /db_xref="GeneID:12688835"
     gene            295211..295549
                     /locus_tag="ECOK1_0268"
                     /db_xref="GeneID:12688836"
     CDS             295211..295549
                     /locus_tag="ECOK1_0268"
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="YP_006099513.1"
                     /db_xref="GI:386598007"
                     /db_xref="GeneID:12688836"
                     /translation="MKLNARQIDTAKPKEKAYKLADGGGLYLLVKPGGGEYWRLKYRV
                     AGKEKLLALGVYPEVTLADAPAKLEEAKRGISGGIDLMEVKREEKIARETQLNNTFKD
                     IALEWHSNKL"
     misc_feature    295217..295477
                     /locus_tag="ECOK1_0268"
                     /note="Domain of unknown function (DUF4102); Region:
                     DUF4102; pfam13356"
                     /db_xref="CDD:257685"
     gene            complement(295984..296478)
                     /locus_tag="ECOK1_0269"
                     /db_xref="GeneID:12688837"
     CDS             complement(295984..296478)
                     /locus_tag="ECOK1_0269"
                     /note="identified by match to protein family HMM PF01047"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="YP_006099514.1"
                     /db_xref="GI:386598008"
                     /db_xref="GeneID:12688837"
                     /translation="MNNIDLLKTITNYKKIKNPAYPAQESLLIHLYIRVNDKIQSIIE
                     NELSEYRINTSTFMVLVSLYMSDDYCQSPSDIYKELQFSKTNITHIIDKLEKKNIAKR
                     INNKNDRRSKSICLTPDGVTLAQKLINTQNVMLKKIWSGLSDDEMKTFELANKKLLSN
                     LNVN"
     misc_feature    complement(295993..296445)
                     /locus_tag="ECOK1_0269"
                     /note="MarR family; Region: MarR_2; cl17246"
                     /db_xref="CDD:266584"
     misc_feature    complement(296005..296361)
                     /locus_tag="ECOK1_0269"
                     /note="Transcriptional regulators [Transcription]; Region:
                     MarR; COG1846"
                     /db_xref="CDD:224759"
     gene            complement(296634..300764)
                     /gene="hbp"
                     /locus_tag="ECOK1_0270"
                     /db_xref="GeneID:12688838"
     CDS             complement(296634..300764)
                     /gene="hbp"
                     /locus_tag="ECOK1_0270"
                     /EC_number="3.4.21.-"
                     /note="identified by similarity to SP:O88093; match to
                     protein family HMM PF02395; match to protein family HMM
                     PF03797; match to protein family HMM TIGR01414"
                     /codon_start=1
                     /transl_table=11
                     /product="hemoglobin-binding protease Hbp"
                     /protein_id="YP_006099515.1"
                     /db_xref="GI:386598009"
                     /db_xref="GeneID:12688838"
                     /translation="MNKIYALKYCYITNTVKVVSELARRVCKGSTRRGKRLSVLTSLA
                     LSALLPTVAGASTVGGNNPYQTYRDFAENKGQFQAGATNIPIFNNKGELVGHLDKAPM
                     VDFSSVNVSSNPGVATLINPQYIASVKHNKGYQSVSFGDGQNSYHIVDRNEHSSSDLH
                     TPRLDKLVTEVAPATVTSSSTADILNPSKYSAFYRAGSGSQYIQDSQGKRHWVTGGYG
                     YLTGGILPTSFFYHGSDGIQLYMGGNIHDHSILPSFGEAGDSGSPLFGWNTAKGQWEL
                     VGVYSGVGGGTNLIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPLQWKFDSSTGTGSL
                     KQGSDEYAMHGQKGSDLNAGKNLTFLGHNGQIDLENSVTQGAGSLTFTDDYTVTTSNG
                     STWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLN
                     QQADSSGHVQAFSSVNIASGRPTVVLADNQQVNPDNISWGYRGGVLDVNGNDLTFHKL
                     NAADYGATLGNSSDKTANITLDYQTRPADVKVNEWSSSNRGTVGSLYIYNNPYTHTVD
                     YFILKTSSYGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGYLYHGKLLGNINFS
                     NKATPGTTGALVMDGSANMSGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSV
                     LTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRNATLNTTIQADNSSVTLGDSRVFID
                     KKDGQGTAFTLEEGTSVATKDADKSVFNGTVNLDNQSVLNINEIFNGGIQANNSTVNI
                     SSDSAVLENSTLTSTALNLNKGANVLASQSFVSDGPVNISDATLSLNSRPDEVSHTLL
                     PVYDYAGSWNLKGDDARLNVGPYSMLSGNINVQDKGTVTLGGEGELSPDLTLQNQMLY
                     SLFNGYRNTWSGSLNAPDATVSMTDTQWSMNGNSTAGNMKLNRTIVGFNGGTSSFTTL
                     TTDNLDAVQSAFVMRTDLNKADKLVINKSATGHDNSIWVNFLKKPSDKDTLDIPLVSA
                     PEATADNLFRASTRVVGFSDVTPTLSVRKEDGKKEWVLDGYQVARNDGQGKAAATFMH
                     ISYNNFITEVNNLNKRMGDLRDINGEAGTWVRLLNGSGSADGGFTDHYTLLQMGADRK
                     HELGSMDLFTGVMATYTDTDASAGLYSGKTKSWGGGFYASGLFRSGAYFDLIAKYIHN
                     ENKYDLNFAGAGKQNFRSHSLYAGAEVGYRYHLTDTTFVEPQAELVWGRLQGQTFNWN
                     DSGMDVSMRRNSVNPLVGRTGVVSGKTFSGKDWSLTGRAGLHYEFDLTDSADVHLKDA
                     AGEHQINGRKDGRMLYGVGLNARFGDNTRLGLEVERSAFGKYNTDDAINANIRYSF"
     misc_feature    complement(300693..300764)
                     /gene="hbp"
                     /locus_tag="ECOK1_0270"
                     /note="Extended Signal Peptide of Type V secretion system;
                     Region: ESPR; pfam13018"
                     /db_xref="CDD:257462"
     misc_feature    complement(298338..300578)
                     /gene="hbp"
                     /locus_tag="ECOK1_0270"
                     /note="Immunoglobulin A1 protease; Region: Peptidase_S6;
                     pfam02395"
                     /db_xref="CDD:251269"
     misc_feature    complement(297540..298286)
                     /gene="hbp"
                     /locus_tag="ECOK1_0270"
                     /note="Pertactin-like passenger domains (virulence
                     factors), C-terminal, subgroup 1, of autotransporter
                     proteins of the type V secretion system of Gram-negative
                     bacteria. This subgroup includes the passenger domains of
                     Neisseria and Haemophilus IgA1 proteases; Region:
                     PL1_Passenger_AT; cd01343"
                     /db_xref="CDD:238653"
     misc_feature    complement(296637..297872)
                     /gene="hbp"
                     /locus_tag="ECOK1_0270"
                     /note="outer membrane autotransporter barrel domain;
                     Region: autotrans_barl; TIGR01414"
                     /db_xref="CDD:233402"
     misc_feature    complement(296676..297431)
                     /gene="hbp"
                     /locus_tag="ECOK1_0270"
                     /note="Autotransporter beta-domain; Region:
                     Autotransporter; pfam03797"
                     /db_xref="CDD:252169"
     gene            301874..302050
                     /locus_tag="ECOK1_0271"
                     /note="conserved domain protein; this gene contains a
                     frame shift which may be the result of a sequencing error;
                     identified by match to protein family HMM PF03400"
                     /pseudo
                     /db_xref="GeneID:12688839"
     gene            302474..302659
                     /locus_tag="ECOK1_0272"
                     /db_xref="GeneID:12688840"
     CDS             302474..302659
                     /locus_tag="ECOK1_0272"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099516.1"
                     /db_xref="GI:386598010"
                     /db_xref="GeneID:12688840"
                     /translation="MASGLICHGGFKPHAWGVASLMDVTVLVVASLLVWLLVNRENHY
                     ARGIPQDVQVLHKKAHH"
     gene            302874..303488
                     /locus_tag="ECOK1_0273"
                     /db_xref="GeneID:12688841"
     CDS             302874..303488
                     /locus_tag="ECOK1_0273"
                     /note="identified by similarity to GB:CAG73364.1; match to
                     protein family HMM PF07274"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099517.1"
                     /db_xref="GI:386598011"
                     /db_xref="GeneID:12688841"
                     /translation="MNIFEQTPPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSP
                     VDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRDWLGLTDPNSAVYTFAGHVFNWV
                     GVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDL
                     PWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR"
     misc_feature    302880..303473
                     /locus_tag="ECOK1_0273"
                     /note="Predicted periplasmic/secreted protein [Function
                     unknown]; Region: COG3477"
                     /db_xref="CDD:226008"
     gene            303786..303911
                     /locus_tag="ECOK1_0274"
                     /db_xref="GeneID:12688842"
     CDS             303786..303911
                     /locus_tag="ECOK1_0274"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099518.1"
                     /db_xref="GI:386598012"
                     /db_xref="GeneID:12688842"
                     /translation="MTSPFSPDMANSLHVDDRFSYIVQQAFLPGVPARAIHRGFF"
     gene            complement(303922..304035)
                     /locus_tag="ECOK1_0275"
                     /db_xref="GeneID:12688843"
     CDS             complement(303922..304035)
                     /locus_tag="ECOK1_0275"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099519.1"
                     /db_xref="GI:386598013"
                     /db_xref="GeneID:12688843"
                     /translation="MPVVHFSASLFTGPKPTMLAVPFPPGSLNKYPLFTDA"
     gene            complement(304373..305083)
                     /locus_tag="ECOK1_0276"
                     /db_xref="GeneID:12688844"
     CDS             complement(304373..305083)
                     /locus_tag="ECOK1_0276"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099520.1"
                     /db_xref="GI:386598014"
                     /db_xref="GeneID:12688844"
                     /translation="MFRRRGVTLTKALLTVVCMLAAPLTQAISVGNLTFSLPSETDFV
                     SKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFY
                     YHGPRDNRERYYRVSFREVPTRNLTKRSPSGGEVSTEPVVVMDTILVVRPRQVQFKWS
                     FDQVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYN
                     DKFIKISDSCPAKPPSAD"
     gene            complement(305052..306695)
                     /locus_tag="ECOK1_0277"
                     /db_xref="GeneID:12688845"
     CDS             complement(305052..306695)
                     /locus_tag="ECOK1_0277"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099521.1"
                     /db_xref="GI:386598015"
                     /db_xref="GeneID:12688845"
                     /translation="MRVNLLIAMIIFALIWPATALRAAVSKTTWADAPAREFVFVENN
                     SDDNFFVTPGGALDPRLTGANRWTGLKYNGSGTIYQQSLGYIDNGYNTGLYTNWKFDM
                     WLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDASGFYGATVTSGGAKWMHGMLS
                     DAFYQYLQQMPVGSSFTMTINACQTSVNYDANSGARCKDQASGNWYVRNVTHTKAANL
                     RLINTHSLAEVFINSDGVPTLGEGNADCRTQTIGSRSGLSCKMVNYTLQTNGLSNTSI
                     HIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEMKSADSIYVFFSSNF
                     FKQMVNLGISDINTKDLFNFRFQNTTSPESGWYEFSTSNTLIIKPRDFSISIISDEYT
                     QTPSREGYVGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGK
                     AKVPFPATLSFITRNGATKTYDAGCDDSWRDMTDALWLTTPWTDISGEVGQMDKTTVK
                     FSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN"
     gene            complement(306685..309210)
                     /locus_tag="ECOK1_0278"
                     /db_xref="GeneID:12688846"
     CDS             complement(306685..309210)
                     /locus_tag="ECOK1_0278"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099522.1"
                     /db_xref="GI:386598016"
                     /db_xref="GeneID:12688846"
                     /translation="MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQ
                     AFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASV
                     SEQTRQQLMTLANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSED
                     IGQSSVNTLSSNLSYNFGVYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIG
                     SGQQDSELYKAMYERDFAGHRFAGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASST
                     IFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEV
                     IVNGRVISKRTQRVNKLFSRGRGVGAPLAWQIWGGSFHMDRWSENGKKTRPAKESWLA
                     GASTSGSLSTFSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSNIASI
                     SATLPGGFSSLWVNQEKTRIGNQLRRSDADNRAIGGTLNLNSLWSKLGTFSISYNDDR
                     RYNSHYYTADYYQSVYSGTFGSLGLRAGIQRYNNGDSSANTGKYIALDLSLPLGNWFS
                     AGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARY
                     ASGTLNVNSAADGYINTNLTANGSVGWQGKNIAASGRTDGNAGVIFDTGLENDGQISA
                     KINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSYDIVSGRKSHLTLYPGNVAVI
                     EPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYS
                     GNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES"
     misc_feature    complement(306739..>308523)
                     /locus_tag="ECOK1_0278"
                     /note="fimbrial outer membrane usher protein TcfC;
                     Provisional; Region: PRK15310"
                     /db_xref="CDD:185210"
     misc_feature    complement(307204..>307752)
                     /locus_tag="ECOK1_0278"
                     /note="Outer membrane usher protein; Region: Usher;
                     pfam00577"
                     /db_xref="CDD:249973"
     misc_feature    complement(<306781..306966)
                     /locus_tag="ECOK1_0278"
                     /note="Domain of unknown function (DUF4480); Region:
                     DUF4480; pfam13715"
                     /db_xref="CDD:258012"
     gene            complement(309236..309904)
                     /locus_tag="ECOK1_0279"
                     /db_xref="GeneID:12688847"
     CDS             complement(309236..309904)
                     /locus_tag="ECOK1_0279"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099523.1"
                     /db_xref="GI:386598017"
                     /db_xref="GeneID:12688847"
                     /translation="MKKHLLPLALLFSGISPAQALDVGDISSFMNSDSSTLSKTIQNS
                     TDSGRLINIRLERLSSPLDDGQVIAMDKPDELLLTPASLLLPAQASEVIRFFYKGPAD
                     EKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGSLT
                     NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTHVDTADNKGRVALWQGDKF
                     IPVK"
     misc_feature    complement(<309380..309892)
                     /locus_tag="ECOK1_0279"
                     /note="putative fimbrial protein TcfA; Provisional;
                     Region: PRK15308"
                     /db_xref="CDD:237939"
     gene            complement(309961..310548)
                     /gene="matB"
                     /locus_tag="ECOK1_0280"
                     /db_xref="GeneID:12688848"
     CDS             complement(309961..310548)
                     /gene="matB"
                     /locus_tag="ECOK1_0280"
                     /note="identified by similarity to GB:AAK01671.1"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrillin MatB"
                     /protein_id="YP_006099524.1"
                     /db_xref="GI:386598018"
                     /db_xref="GeneID:12688848"
                     /translation="MKKKVLAIALVTVFTGTGVAQAADVTAQAVATWSATAKKDTTSK
                     LVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSG
                     STLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSII
                     SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS"
     gene            complement(310622..311212)
                     /gene="matA"
                     /locus_tag="ECOK1_0281"
                     /db_xref="GeneID:12688849"
     CDS             complement(310622..311212)
                     /gene="matA"
                     /locus_tag="ECOK1_0281"
                     /note="identified by similarity to GB:AAK01670.1; match to
                     protein family HMM PF00196"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrillin MatA"
                     /protein_id="YP_006099525.1"
                     /db_xref="GI:386598019"
                     /db_xref="GeneID:12688849"
                     /translation="MTWQNDYSRDYEVKNHMECQNRSDKYIWSPHDAYFYKGLSELIV
                     DIDRLIYLSLEKIRKDFVFINLNTDSLTEFINRDNEWLSAVKGKQVVLIAARKSEALA
                     NYWYYNSNIRGVVYAGLSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGM
                     LPKSIARIENCSVKTVYTHRRNAEAKLYSKLYKLVQ"
     misc_feature    complement(310640..>310777)
                     /gene="matA"
                     /locus_tag="ECOK1_0281"
                     /note="Response regulator containing a CheY-like receiver
                     domain and an HTH DNA-binding domain [Signal transduction
                     mechanisms / Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     misc_feature    complement(<310652..310777)
                     /gene="matA"
                     /locus_tag="ECOK1_0281"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(310670..310684,310688..310693,
                     310697..310702,310724..310732,310769..310777))
                     /gene="matA"
                     /locus_tag="ECOK1_0281"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     gene            complement(312248..312388)
                     /gene="rpmJ"
                     /locus_tag="ECOK1_0282"
                     /db_xref="GeneID:12688850"
     CDS             complement(312248..312388)
                     /gene="rpmJ"
                     /locus_tag="ECOK1_0282"
                     /note="identified by match to protein family HMM PF00444;
                     match to protein family HMM TIGR01022"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="YP_006099526.1"
                     /db_xref="GI:386598020"
                     /db_xref="GeneID:12688850"
                     /translation="MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKK
                     KR"
     misc_feature    complement(312266..312388)
                     /gene="rpmJ"
                     /locus_tag="ECOK1_0282"
                     /note="50S ribosomal protein L36; Validated; Region: rpmJ;
                     PRK00831"
                     /db_xref="CDD:179138"
     gene            complement(312388..312654)
                     /gene="rpmE2"
                     /locus_tag="ECOK1_0283"
                     /db_xref="GeneID:12688851"
     CDS             complement(312388..312654)
                     /gene="rpmE2"
                     /locus_tag="ECOK1_0283"
                     /note="identified by match to protein family HMM PF01197;
                     match to protein family HMM TIGR00105"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="YP_006099527.1"
                     /db_xref="GI:386598021"
                     /db_xref="GeneID:12688851"
                     /translation="MMKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYP
                     YVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA"
     misc_feature    complement(312394..312651)
                     /gene="rpmE2"
                     /locus_tag="ECOK1_0283"
                     /note="50S ribosomal protein L31 type B; Reviewed; Region:
                     rpmE2; PRK01678"
                     /db_xref="CDD:234969"
     gene            complement(313591..314733)
                     /locus_tag="ECOK1_0284"
                     /db_xref="GeneID:12688852"
     CDS             complement(313591..314733)
                     /locus_tag="ECOK1_0284"
                     /note="identified by match to protein family HMM PF00724"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase FAD/FMN-binding protein"
                     /protein_id="YP_006099528.1"
                     /db_xref="GI:386598022"
                     /db_xref="GeneID:12688852"
                     /translation="MTNKHPSLFSPFMLTEKIKLRNRIVMAPMTTWSANPDGTISEQE
                     LEFYKRRSQNVGLVITGCTYVTPSGIGFTHEFAAYDDRFINSLEKLAAAAKSGGAPAI
                     LQIFHAGNKAIPELVPNNDVISASASSVKSGDFMKRVVQSREMTENEIQETIRAFGDV
                     TKRAIKAGFDGVELHGAHGFLLQNFFSPLFNQRNDRWGGDLEGRMRFPLAVLQEVKNV
                     VYEYATKPFAIGYRISPEESVTGGLRIEDTYKLLDRLISSGISYIHTSLVSINDSYPV
                     ESPNGPRTIELILNHIAGRVPVIAAGKIRTPSQAQEAISAGLPLVAIGKGLVINPEWV
                     TLAESGRSHEIQTALNPQRVPELTIPDKLWDQIQASKGTGWFPLMD"
     misc_feature    complement(313642..314712)
                     /locus_tag="ECOK1_0284"
                     /note="Old yellow enzyme (OYE)-related FMN binding domain,
                     group 4.  Each monomer of OYE contains FMN as a
                     non-covalently bound cofactor, uses NADPH as a reducing
                     agent with oxygens, quinones, and alpha,beta-unsaturated
                     aldehydes and ketones, and can act as...; Region:
                     OYE_like_4_FMN; cd04735"
                     /db_xref="CDD:240086"
     misc_feature    complement(order(313759..313764,314026..314028,
                     314194..314196,314422..314424,314548..314550,
                     314644..314646,314650..314652))
                     /locus_tag="ECOK1_0284"
                     /note="putative active site [active]"
                     /db_xref="CDD:240086"
     misc_feature    complement(order(313759..313764,314026..314028,
                     314422..314424,314548..314550,314644..314646,
                     314650..314652))
                     /locus_tag="ECOK1_0284"
                     /note="putative FMN binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:240086"
     misc_feature    complement(order(314194..314196,314200..314202))
                     /locus_tag="ECOK1_0284"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:240086"
     misc_feature    complement(314194..314196)
                     /locus_tag="ECOK1_0284"
                     /note="putative catalytic residue [active]"
                     /db_xref="CDD:240086"
     gene            complement(314905..315825)
                     /locus_tag="ECOK1_0285"
                     /db_xref="GeneID:12688853"
     CDS             complement(314905..315825)
                     /locus_tag="ECOK1_0285"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099529.1"
                     /db_xref="GI:386598023"
                     /db_xref="GeneID:12688853"
                     /translation="MKTVSIKHTYWDIAADIYFPDDFNSEKKYPAIISAHPIGSCKEQ
                     TSGSVYGAALAKAGFIVIAFDASFQGSSGGEPRYLEDPTMRVKDFSIVVDYLTTLPYV
                     DAGRIGVLGICGGGGYAINAAMTERRIKAIGTVTGANYGRLMREGFTAFNPIGALEAM
                     AQQRTDEANGAKLRVDDLLPSSPEAALEAGLTEIDLFEATEYYRSPRGCAPNGVNRSL
                     FSHQTVAVGWDAFHLAEVLLTQPLMVVVGDRVGAFGAYRDGCEIIGRAASKHKELVVV
                     EGYSHYDLYDKPEPVKQALDKLIPFYKTHL"
     misc_feature    complement(314908..315804)
                     /locus_tag="ECOK1_0285"
                     /note="Hydrolases of the alpha/beta superfamily [General
                     function prediction only]; Region: COG1073"
                     /db_xref="CDD:223999"
     misc_feature    complement(<315529..315744)
                     /locus_tag="ECOK1_0285"
                     /note="Prolyl oligopeptidase family; Region: Peptidase_S9;
                     cl19144"
                     /db_xref="CDD:267497"
     gene            315919..316908
                     /locus_tag="ECOK1_0286"
                     /db_xref="GeneID:12688854"
     CDS             315919..316908
                     /locus_tag="ECOK1_0286"
                     /note="identified by match to protein family HMM PF00126;
                     match to protein family HMM PF03466"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_006099530.1"
                     /db_xref="GI:386598024"
                     /db_xref="GeneID:12688854"
                     /translation="MTCIGYHQWSNIYHSVKLRFTMMKIEPSILPSLAWFALIVRAGS
                     FSRAASEMGITRAALSQNLKSLEERLNTKLIYRTTRNMSLTEEGQHLYEVLVSALGQI
                     DDALKDVGDTQLEPTGLLRINSSRVAARMLVEPHIGEFLTRYPKTKIELIMDDGLSNI
                     IADGCDVGIRLEQGLDEHMTAVPVSPLIKLVTVASPDYLKEHGIPETPQELSNHNCLR
                     LRHKSSGALSAWEFSNVVGGNEEFEIEVSGKYISNDDESMIRMALNGTGIIQHLDFAI
                     AEHINAGKLQPILEDWAVSFPGFYIYVSSRVRMPSKVRAFIDFMVEKRVKIES"
     misc_feature    316006..316884
                     /locus_tag="ECOK1_0286"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    316015..316185
                     /locus_tag="ECOK1_0286"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    316264..316878
                     /locus_tag="ECOK1_0286"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     Region: PBP2_CrgA_like_5; cd08474"
                     /db_xref="CDD:176163"
     misc_feature    order(316300..316302,316312..316314,316429..316431,
                     316471..316473,316480..316482,316681..316683,
                     316732..316734,316813..316815)
                     /locus_tag="ECOK1_0286"
                     /note="putative effector binding pocket; other site"
                     /db_xref="CDD:176163"
     misc_feature    order(316303..316308,316318..316323,316327..316332,
                     316339..316341,316351..316353,316357..316377,
                     316561..316563,316663..316677,316696..316701,
                     316708..316710)
                     /locus_tag="ECOK1_0286"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176163"
     gene            317108..318001
                     /locus_tag="ECOK1_0287"
                     /db_xref="GeneID:12688855"
     CDS             317108..318001
                     /locus_tag="ECOK1_0287"
                     /note="identified by match to protein family HMM PF00126;
                     match to protein family HMM PF03466"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_006099531.1"
                     /db_xref="GI:386598025"
                     /db_xref="GeneID:12688855"
                     /translation="MLKENFNELQIFLVVARERSFTKAAGKLGVSQSALSHAMKALEE
                     RLNIRLLTRTTRSVAPTEAGERIIACLEPRIDELEQELESLIQLNGTPSGNIRLSAGE
                     HAARSLVWPKLKPFLREYPEINVELVVDNGFVDIVEGRFDAGIRLGENVDKDMVAVRI
                     GPDMRMAVVGAPAYFAANPAPETPHELQNHRCINMRLPTAGGLYHWEFEREGKPLRVK
                     VDGQLTCSPLPERIDAALSGFGIACVPEDMVQEYIESGKLIQVLQEWCPTFPGYYLYY
                     PSRKQHPPAFALLIDALRYTE"
     misc_feature    317120..317989
                     /locus_tag="ECOK1_0287"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    317123..317302
                     /locus_tag="ECOK1_0287"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:249610"
     misc_feature    317381..317986
                     /locus_tag="ECOK1_0287"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     Region: PBP2_CrgA_like_5; cd08474"
                     /db_xref="CDD:176163"
     misc_feature    order(317417..317419,317429..317431,317546..317548,
                     317588..317590,317597..317599,317789..317791,
                     317840..317842,317921..317923)
                     /locus_tag="ECOK1_0287"
                     /note="putative effector binding pocket; other site"
                     /db_xref="CDD:176163"
     misc_feature    order(317420..317425,317435..317440,317444..317449,
                     317456..317458,317468..317470,317474..317494,
                     317678..317680,317771..317785,317804..317809,
                     317816..317818)
                     /locus_tag="ECOK1_0287"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176163"
     gene            complement(318032..319021)
                     /locus_tag="ECOK1_0288"
                     /db_xref="GeneID:12688856"
     CDS             complement(318032..319021)
                     /locus_tag="ECOK1_0288"
                     /note="identified by match to protein family HMM PF00248"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase, aldo/keto reductase family"
                     /protein_id="YP_006099532.1"
                     /db_xref="GI:386598026"
                     /db_xref="GeneID:12688856"
                     /translation="MQKRYLGKSGLEVSALGLGCMGLSHGYGPATDTRQAIELIRAAI
                     ERGVTFFDTAEVYGPYLNEEVVGEALKPFRDRVVIATKFGFTFGDDNKQQILNSRPEH
                     IREAVEGSLRRLKTDVIDLLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQ
                     TIRRAHAVQPVTALQSEYSMWWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKPG
                     TTFGKDDYRSTVPRFAAQAIEANEKLVTLLGELAAEKGVTSAQIALAWLLAQKPWIVP
                     IPGTTKLHRLEENLAAADIVLSQKDTQQISEALETIKIVGERYSPEHQARVGR"
     misc_feature    complement(318098..319015)
                     /locus_tag="ECOK1_0288"
                     /note="Aldo-keto reductases (AKRs) are a superfamily of
                     soluble NAD(P)(H) oxidoreductases whose chief purpose is
                     to reduce aldehydes and ketones to primary and secondary
                     alcohols. AKRs are present in all phyla and are of
                     importance to both health and industrial...; Region:
                     Aldo_ket_red; cd06660"
                     /db_xref="CDD:119408"
     misc_feature    complement(318086..319012)
                     /locus_tag="ECOK1_0288"
                     /note="voltage-dependent potassium channel beta subunit,
                     animal; Region: Kv_beta; TIGR01293"
                     /db_xref="CDD:213602"
     misc_feature    complement(order(318155..318160,318167..318169,
                     318182..318193,318242..318244,318398..318415,
                     318497..318499,318554..318559,318644..318649,
                     318776..318778,318851..318853,318866..318868,
                     318959..318967))
                     /locus_tag="ECOK1_0288"
                     /note="active site"
                     /db_xref="CDD:119408"
     misc_feature    complement(order(318647..318649,318776..318778,
                     318851..318853,318866..318868))
                     /locus_tag="ECOK1_0288"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:119408"
     gene            complement(319048..319899)
                     /locus_tag="ECOK1_0289"
                     /db_xref="GeneID:12688857"
     CDS             complement(319048..319899)
                     /locus_tag="ECOK1_0289"
                     /note="identified by match to protein family HMM PF00248"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase, aldo/keto reductase family"
                     /protein_id="YP_006099533.1"
                     /db_xref="GI:386598027"
                     /db_xref="GeneID:12688857"
                     /translation="MQKVKLNNGIEMPLLGFGVFQMTDAAECERAVIDAINSGYRLID
                     TAASYQNEIQVGNALKQSGIARNELFVTTKLWLQDTSYEGAKAQFERSLNRLQLDYVD
                     LYLIHQPYGDVHGAWRAMEELQQAGKIRAIGVSNFHPDRLADLIAFNNVVPAVNQVEV
                     NPFNQQLQAVPWMQSRGIQPEAWAPFAEGKNGLFQHPVLTAIGEKYGKSVGQVVLRWI
                     YQRGIVSLAKSVRKERMEENINILDFELSPEDMLQITALDTATSAFFSHRDPAMVEWL
                     TGRKLDV"
     misc_feature    complement(319129..319893)
                     /locus_tag="ECOK1_0289"
                     /note="Aldo-keto reductases (AKRs) are a superfamily of
                     soluble NAD(P)(H) oxidoreductases whose chief purpose is
                     to reduce aldehydes and ketones to primary and secondary
                     alcohols. AKRs are present in all phyla and are of
                     importance to both health and industrial...; Region:
                     Aldo_ket_red; cd06660"
                     /db_xref="CDD:119408"
     misc_feature    complement(319129..319878)
                     /locus_tag="ECOK1_0289"
                     /note="voltage-dependent potassium channel beta subunit,
                     animal; Region: Kv_beta; TIGR01293"
                     /db_xref="CDD:213602"
     misc_feature    complement(order(319186..319191,319198..319200,
                     319213..319224,319267..319269,319336..319353,
                     319429..319431,319492..319497,319576..319581,
                     319678..319680,319753..319755,319768..319770,
                     319840..319848))
                     /locus_tag="ECOK1_0289"
                     /note="active site"
                     /db_xref="CDD:119408"
     misc_feature    complement(order(319579..319581,319678..319680,
                     319753..319755,319768..319770))
                     /locus_tag="ECOK1_0289"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:119408"
     gene            320465..324715
                     /locus_tag="ECOK1_0290"
                     /db_xref="GeneID:12688858"
     CDS             320465..324715
                     /locus_tag="ECOK1_0290"
                     /note="identified by match to protein family HMM PF02369"
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain (group 1) protein"
                     /protein_id="YP_006099534.1"
                     /db_xref="GI:386598028"
                     /db_xref="GeneID:12688858"
                     /translation="MSRYKTDNKQPRFRYSVLARCVAWANISVQVLFPLAVTFTPVMA
                     ARAQHAVQPRLSMENTTVTADNNVEKNVASLAANAGTFLSSQPDSDATRNFITGMATA
                     KANQEIQEWLGKYGTARVKLNVDKNFSLKDSSLEMLYPIYDTPTNMLFTQGAIHRTDD
                     RTQSNIGFGWRHFSENDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGYIRA
                     SGWKKSPDVEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQK
                     DPHAITAEVNYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLEKQLDTDSIRE
                     RRMLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTVSLGLVVSKATHGLK
                     NVQWEAPSLLAAGGKITGQGNQWQVTLPAYQAGKDNYYAISAIAYDNKGNASKRVQTE
                     VVISGAGMSADRTALTLDGQSRIQMLANGNEQKPLVLSLRDAEGQPVTGMKDQIKTEL
                     TFKPAGNIVTRTLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDDMS
                     KTVTAELRATMMDVSNSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLR
                     LVPQDTNGVTVGAISEIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP
                     LDAAHSSITLNPDKPVVGGTVTAIWTAKDANDNPVTGLNPDAPSLSGAAAAGSTASGW
                     TDNGDGTWTAQISLGTTAGELDVMPKLNGQDAAANAAKVTVVADALSSNQSKVSVAED
                     HVKAGESTTVTLVAKDAHGNAISGLSLSASLTGTASEGATVSSWTEKGDGSYVATLTT
                     GGKTGELRVMPLFNGQPAATEAAQLTVIAGEMSSANSTLVADNKTPTVKTTTELTFTM
                     KDAYGNPVTGLKPDAPVFSGAASTGSERPSAGNWTEKGNGVYVSTLTLGSAAGQLSVM
                     PRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVNNQLANGQSANQITLTVVDSYGNPL
                     QGQEVTLTLPQGVTSKTGNTVTTNAAGKVDIELMSTVAGELEIEASVKNSQKTVKVKF
                     KADFSTGQASLEVDAAAQKVANGKDAFTLTATVKDQYGNLLPGAVVVFNLPRGVKPLA
                     DGNIMVNADKEGKAELKVVSVTAGTYEITASAGNDQPSNAQSVTFVADKTTATISSIE
                     VIGNRAVADGKTKQTYKVTVTDANNNLLKDSEVTLTASPENLVLTPNGTATTNEQGQA
                     IFTATTTVAATYTLTAKVEQADGQESTKTAESKFVADDKNAVLAASPERVDSLVADGK
                     TTATLTVTLMSGVNPVGGTMWVDIEAPEGVTEADYQFLPSKNDHFASGKITRTFSTNK
                     PGTYTFTFNSLTYGGYEMKPVTVTINAVPADTEGAEEK"
     misc_feature    320672..321514
                     /locus_tag="ECOK1_0290"
                     /note="Protein of unknown function (DUF3442); Region:
                     DUF3442; pfam11924"
                     /db_xref="CDD:256730"
     misc_feature    322211..322486
                     /locus_tag="ECOK1_0290"
                     /note="Bacterial Ig-like domain (group 1); Region: BID_1;
                     smart00634"
                     /db_xref="CDD:214751"
     misc_feature    323459..323722
                     /locus_tag="ECOK1_0290"
                     /note="Bacterial Ig-like domain (group 1); Region: BID_1;
                     smart00634"
                     /db_xref="CDD:214751"
     misc_feature    323786..324028
                     /locus_tag="ECOK1_0290"
                     /note="Bacterial Ig-like domain (group 1); Region: BID_1;
                     smart00634"
                     /db_xref="CDD:214751"
     misc_feature    324059..>324256
                     /locus_tag="ECOK1_0290"
                     /note="Bacterial Ig-like domain (group 1); Region: BID_1;
                     smart00634"
                     /db_xref="CDD:214751"
     gene            complement(324840..325697)
                     /locus_tag="ECOK1_0291"
                     /db_xref="GeneID:12688859"
     CDS             complement(324840..325697)
                     /locus_tag="ECOK1_0291"
                     /note="identified by match to protein family HMM PF00165;
                     match to protein family HMM PF06445"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="YP_006099535.1"
                     /db_xref="GI:386598029"
                     /db_xref="GeneID:12688859"
                     /translation="MIRQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN
                     FMHVPLGEYIRKRRLCRAAILVRLSAKSMLDIALSLHFDSQQSFSREFKKLFGCSPRE
                     YRHRDYWDLANIFPSFLIRQQQKTECRLVNFPETPIFGNSFKYDIEVSNKLPDEEVKL
                     RRHHLVRCMKNFKTDIYFVSTFEPSTKSVDLLTVETFAGTVCKQTDSEMPKEWTINRG
                     LYASFRYEGEWEHYPEWARNLYLMELPARGLARVNGSDIERFYYNENFVEIDSNNIVC
                     EIFIPVRPV"
     misc_feature    complement(324849..325682)
                     /locus_tag="ECOK1_0291"
                     /note="right oriC-binding transcriptional activator;
                     Provisional; Region: PRK15121"
                     /db_xref="CDD:185076"
     misc_feature    complement(325533..325658)
                     /locus_tag="ECOK1_0291"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:249644"
     misc_feature    complement(325383..>325484)
                     /locus_tag="ECOK1_0291"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:249644"
     misc_feature    complement(324849..325319)
                     /locus_tag="ECOK1_0291"
                     /note="Bacterial transcription activator, effector binding
                     domain; Region: AraC_E_bind; smart00871"
                     /db_xref="CDD:214874"
     gene            325945..326814
                     /locus_tag="ECOK1_0292"
                     /db_xref="GeneID:12688860"
     CDS             325945..326814
                     /locus_tag="ECOK1_0292"
                     /note="identified by match to protein family HMM PF00248"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase, aldo/keto reductase family"
                     /protein_id="YP_006099536.1"
                     /db_xref="GI:386598030"
                     /db_xref="GeneID:12688860"
                     /translation="MEFSVLSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLID
                     TAAVYGNEDAVGEAVREAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSG
                     LEYFDLYLLHQAMRDYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMV
                     NQVELHPYFAQPEALATMKYYNVQPEAWAPLGGGRHKPFENNLLQSIADAHQKSISQV
                     ILRWNIQRGVVVIPKSTHQQRIEENFAIWDFSLTEKEMAQISSLDLGYVGESVKHFNP
                     EFVRGCLAVKIHD"
     misc_feature    325963..326730
                     /locus_tag="ECOK1_0292"
                     /note="Aldo-keto reductases (AKRs) are a superfamily of
                     soluble NAD(P)(H) oxidoreductases whose chief purpose is
                     to reduce aldehydes and ketones to primary and secondary
                     alcohols. AKRs are present in all phyla and are of
                     importance to both health and industrial...; Region:
                     Aldo_ket_red; cd06660"
                     /db_xref="CDD:119408"
     misc_feature    order(325996..326004,326074..326076,326089..326091,
                     326176..326178,326278..326283,326362..326367,
                     326428..326430,326506..326523,326590..326592,
                     326635..326646,326659..326661,326668..326673)
                     /locus_tag="ECOK1_0292"
                     /note="active site"
                     /db_xref="CDD:119408"
     misc_feature    order(326074..326076,326089..326091,326176..326178,
                     326278..326280)
                     /locus_tag="ECOK1_0292"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:119408"
     gene            complement(326974..327567)
                     /locus_tag="ECOK1_0293"
                     /db_xref="GeneID:12688861"
     CDS             complement(326974..327567)
                     /locus_tag="ECOK1_0293"
                     /note="identified by match to protein family HMM PF04224"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099537.1"
                     /db_xref="GI:386598031"
                     /db_xref="GeneID:12688861"
                     /translation="MERYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSIT
                     PFVANSPLMSFFYEHPEDYKQHLTHEGEYKPEARAWQTANNTYGFSNGLGVVEVIIAL
                     LVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSARDILKQRSNESSSTLKTEY"
     misc_feature    complement(327010..327567)
                     /locus_tag="ECOK1_0293"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG3059"
                     /db_xref="CDD:225601"
     gene            complement(327579..327815)
                     /locus_tag="ECOK1_0294"
                     /db_xref="GeneID:12688862"
     CDS             complement(327579..327815)
                     /locus_tag="ECOK1_0294"
                     /note="identified by match to protein family HMM PF07338"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099538.1"
                     /db_xref="GI:386598032"
                     /db_xref="GeneID:12688862"
                     /translation="MFKKSVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLE
                     NAIADMARKYNASSWKVTSMRIDNNSTATAVLYK"
     misc_feature    complement(327582..327725)
                     /locus_tag="ECOK1_0294"
                     /note="Protein of unknown function (DUF1471); Region:
                     DUF1471; pfam07338"
                     /db_xref="CDD:254164"
     gene            complement(327924..329249)
                     /locus_tag="ECOK1_0295"
                     /db_xref="GeneID:12688863"
     CDS             complement(327924..329249)
                     /locus_tag="ECOK1_0295"
                     /note="identified by match to protein family HMM PF00070;
                     match to protein family HMM PF02852; match to protein
                     family HMM PF07992"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="YP_006099539.1"
                     /db_xref="GI:386598033"
                     /db_xref="GeneID:12688863"
                     /translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCI
                     NIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFI
                     NNHSLRVHRPGRNLEIHGEKIFINTGAQAVVPPIPGITTTPGVYDSTGLLNLKELPGH
                     LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIIL
                     NAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVV
                     DKQLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGRRSTDDRKNVPYSVFM
                     TPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRILGA
                     SLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK"
     misc_feature    complement(327927..329249)
                     /locus_tag="ECOK1_0295"
                     /note="pyridine nucleotide-disulfide oxidoreductase;
                     Provisional; Region: PRK08010"
                     /db_xref="CDD:181196"
     misc_feature    complement(<329148..329243)
                     /locus_tag="ECOK1_0295"
                     /note="Squalene epoxidase; Region: SE; cl17314"
                     /db_xref="CDD:266623"
     misc_feature    complement(328545..328739)
                     /locus_tag="ECOK1_0295"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:249559"
     misc_feature    complement(327951..328268)
                     /locus_tag="ECOK1_0295"
                     /note="Pyridine nucleotide-disulphide oxidoreductase,
                     dimerization domain; Region: Pyr_redox_dim; pfam02852"
                     /db_xref="CDD:251571"
     gene            329476..330330
                     /locus_tag="ECOK1_0296"
                     /db_xref="GeneID:12688864"
     CDS             329476..330330
                     /locus_tag="ECOK1_0296"
                     /note="identified by match to protein family HMM PF00165"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="YP_006099540.1"
                     /db_xref="GI:386598034"
                     /db_xref="GeneID:12688864"
                     /translation="MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHAL
                     TQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHVDNESTCIVCGTLRLQHSARYFL
                     TSLPETLFVAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
                     IAQVNTEKNILSLLLHPRLGAVIQQMMEMPGHAWTVESLASIAHMSRASFAQLFRDVS
                     GTTPLAVLTKLRLQIAAQMFSREMLPVVVIAESVGYASESSFHKAFVREFGCTPGEYR
                     ERVRQLAP"
     misc_feature    329479..329961
                     /locus_tag="ECOK1_0296"
                     /note="Cupin; Region: Cupin_6; pfam12852"
                     /db_xref="CDD:257350"
     misc_feature    329959..330324
                     /locus_tag="ECOK1_0296"
                     /note="AraC-type DNA-binding domain-containing proteins
                     [Transcription]; Region: AraC; COG2207"
                     /db_xref="CDD:225117"
     misc_feature    330049..330156
                     /locus_tag="ECOK1_0296"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:249644"
     misc_feature    <330217..330303
                     /locus_tag="ECOK1_0296"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:249644"
     gene            330857..331576
                     /locus_tag="ECOK1_0297"
                     /db_xref="GeneID:12688865"
     CDS             330857..331576
                     /locus_tag="ECOK1_0297"
                     /note="identified by match to protein family HMM PF02754"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099541.1"
                     /db_xref="GI:386598035"
                     /db_xref="GeneID:12688865"
                     /translation="MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQ
                     PAINSGYIKEAIPGMKNLIAALEDNDDPIISPAGSCTYAVKSYPTYLADEPEWASRAE
                     KVAARMQDLTSFIVNTLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
                     ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVAHLMEVRPEYLIGADVSCLLNISG
                     RLQREGQKVKVMHIAEVLMSR"
     misc_feature    <330857..331573
                     /locus_tag="ECOK1_0297"
                     /note="Fe-S oxidoreductase [Energy production and
                     conversion]; Region: GlpC; COG0247"
                     /db_xref="CDD:223325"
     misc_feature    330863..331111
                     /locus_tag="ECOK1_0297"
                     /note="Cysteine-rich domain; Region: CCG; pfam02754"
                     /db_xref="CDD:202376"
     misc_feature    331250..331507
                     /locus_tag="ECOK1_0297"
                     /note="Cysteine-rich domain; Region: CCG; pfam02754"
                     /db_xref="CDD:202376"
     gene            331587..333014
                     /locus_tag="ECOK1_0298"
                     /db_xref="GeneID:12688866"
     CDS             331587..333014
                     /locus_tag="ECOK1_0298"
                     /note="identified by match to protein family HMM PF02589;
                     match to protein family HMM TIGR00273"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster binding protein"
                     /protein_id="YP_006099542.1"
                     /db_xref="GI:386598036"
                     /db_xref="GeneID:12688866"
                     /translation="MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDE
                     LGHWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQNGGHVYFAKTKEDATRYILQVAQ
                     RKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQDPPSHVVVPAIHK
                     DRHQIRRVLHEHLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCL
                     VTNEGNARMCTTLPKTHIAVMGMERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTG
                     PREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMNTCPAYRHIGGHGYG
                     SIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDSVCPVRIPLSKLILRHRRVMAEK
                     GITAKAEQRAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEAR
                     DLPEADGESFRSWFKKHQAQEKKNG"
     misc_feature    331638..332945
                     /locus_tag="ECOK1_0298"
                     /note="iron-sulfur cluster-binding protein; Region:
                     TIGR00273"
                     /db_xref="CDD:129374"
     misc_feature    331800..332468
                     /locus_tag="ECOK1_0298"
                     /note="Uncharacterized ACR, YkgG family COG1556; Region:
                     DUF162; pfam02589"
                     /db_xref="CDD:251397"
     misc_feature    332508..332714
                     /locus_tag="ECOK1_0298"
                     /note="4Fe-4S dicluster domain; Region: Fer4_8; pfam13183"
                     /db_xref="CDD:257551"
     misc_feature    332739..332999
                     /locus_tag="ECOK1_0298"
                     /note="Domain of unknown function (DUF3390); Region:
                     DUF3390; pfam11870"
                     /db_xref="CDD:256687"
     gene            333007..333702
                     /locus_tag="ECOK1_0299"
                     /db_xref="GeneID:12688867"
     CDS             333007..333702
                     /locus_tag="ECOK1_0299"
                     /note="identified by similarity to GB:AAN78905.1; match to
                     protein family HMM PF02589"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099543.1"
                     /db_xref="GI:386598037"
                     /db_xref="GeneID:12688867"
                     /translation="MDNRSKFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTQLTQQ
                     QRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKELGDQSVVISGDTRLEELGISER
                     LQQECNAVVWDPAKGIENISQAEQAKVGVVYAEYGLTESGGVVLFSAAGRGRSLSLLP
                     ESSLFILRKSTILPRVAQLAEKLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVH
                     GPVKAVYLIIEDC"
     misc_feature    333007..333699
                     /locus_tag="ECOK1_0299"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG1556"
                     /db_xref="CDD:224473"
     gene            complement(333945..334613)
                     /locus_tag="ECOK1_0300"
                     /db_xref="GeneID:12688868"
     CDS             complement(333945..334613)
                     /locus_tag="ECOK1_0300"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099544.1"
                     /db_xref="GI:386598038"
                     /db_xref="GeneID:12688868"
                     /translation="MNEQIKQDIDLIEILFYLKKKIRVILFIIAICMVMVLLFLYINK
                     DNIKVTYSLKINQTTPGILVSCDSNNNFACQTTMTEDVIQRITTFFQTSPDVKNREIK
                     LEWSGNKRDLPTAEAEISRVQASIIKWYASEYHNGRQVLDEIQTPSAINSELYTKMIY
                     LTRNWSLYPNGDGCVTISSPEIKNKYPAAICLALGFFLSIVISVMFCLVKKMVDEYQQ
                     NSGQ"
     misc_feature    complement(333978..334211)
                     /locus_tag="ECOK1_0300"
                     /note="G-rich domain on putative tyrosine kinase; Region:
                     GNVR; pfam13807"
                     /db_xref="CDD:258087"
     gene            complement(334797..337094)
                     /locus_tag="ECOK1_0301"
                     /db_xref="GeneID:12688869"
     CDS             complement(334797..337094)
                     /locus_tag="ECOK1_0301"
                     /note="identified by match to protein family HMM PF03797;
                     match to protein family HMM TIGR01414"
                     /codon_start=1
                     /transl_table=11
                     /product="putative outer membrane autotransporter"
                     /protein_id="YP_006099545.1"
                     /db_xref="GI:386598039"
                     /db_xref="GeneID:12688869"
                     /translation="MKNSKAFYRSALATAIVMALSAPAFATDSTVSTDPVTLNTEKTT
                     LDQDVVINGDNKITAVTIETSDSDKDLNVTFGGHDITAASTVNQDFVEGVKVSGNKNV
                     VINATDSTITAQGEGTYVRTAMVIDSTGDVVVNGGNFVAKNEKGSATGISLEATTGNN
                     LTLNGTTINAQGNKSYSNGSTAIFAQKGNLLQGFDGDATDNITLADSNIINGGIETIV
                     TAGNKTGIHTVNLNIKDGSVIGAANNKQTIYASASAQGAGSATQNLNLSVADSTIYSD
                     VLALSESENSASTTTNVNMNVARSYWEGNAYTFNSGDKAGSDLDINLSDSSVWKGKVS
                     GAGDASVSLQNGSVWNVTGSSTVDALAVKDSTVNITKATVNTGTFASQNGTLIVDASS
                     ENTLDISGKASGDLRVYSAGSLDLINEQTAFISTGKDSTLKATGTTEGGLYQYDLTQG
                     ADGNFYFVKNTHKASNASSVIQAMAAAPANVANLQADTLSARQDAVRLSENDKGGVWI
                     QYFGGKQKHTTAGNASYDLDVNGVMLGGDTRFMTEDGSWLAGVAMSSAKGDMTTMQSK
                     GDTEGYSFHAYLSRQYNNGIFIDTAAQFGHYSNTADVRLMNGGGTIKADFNTNGFGAM
                     VKGGYTWKDGNGLFIQPYAKLSALTLEGVDYQLNGVDVHSDSYNSVLGEAGTRVGYDF
                     AVGNATVKPYLNLAALNEFSDGNKVRLGDESVNASIDGAAFRVGAGVQADITKNMGAY
                     ASLDYTKGDDIENPLQGVVGINVTW"
     misc_feature    complement(335712..336344)
                     /locus_tag="ECOK1_0301"
                     /note="Pertactin-like passenger domains (virulence
                     factors) of autotransporter proteins of the type V
                     secretion system. Autotransporters are proteins used by
                     Gram-negative bacteria to transport proteins across their
                     outer membranes. The C-terminal (beta) domain...; Region:
                     PL_Passenger_AT; cl00185"
                     /db_xref="CDD:260243"
     misc_feature    complement(334800..336002)
                     /locus_tag="ECOK1_0301"
                     /note="outer membrane autotransporter barrel domain;
                     Region: autotrans_barl; TIGR01414"
                     /db_xref="CDD:233402"
     misc_feature    complement(334845..335597)
                     /locus_tag="ECOK1_0301"
                     /note="Autotransporter beta-domain; Region:
                     Autotransporter; pfam03797"
                     /db_xref="CDD:252169"
     gene            complement(337136..337897)
                     /locus_tag="ECOK1_0302"
                     /db_xref="GeneID:12688870"
     CDS             complement(337136..337897)
                     /locus_tag="ECOK1_0302"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099546.1"
                     /db_xref="GI:386598040"
                     /db_xref="GeneID:12688870"
                     /translation="MRFVLFCPSGIVPAQFAALSTGSVGNVTCIRTEEELRNKLRHRP
                     QSVVISAGRPAECAEMWFRFYRDHSFVVVLCVAPFFLPPDVSISGVLKNLRLLKPGMS
                     VERVISIANASGGFSGLKHAEILPVMDSYSVFMKEVNNRTKTIVMSERFPEKQKKVLS
                     LLLAGHSWEYSAQFLKTGIRQIWLAEQSLKKRWGIPDSMSLREALLLSSNNFHGDGNA
                     LETTNAMTLRENGNTNRYSVVVNAGTQALSLHKYK"
     gene            complement(338051..338845)
                     /locus_tag="ECOK1_0303"
                     /db_xref="GeneID:12688871"
     CDS             complement(338051..338845)
                     /locus_tag="ECOK1_0303"
                     /note="identified by match to protein family HMM PF00196"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH luxR-type DNA-binding domain protein"
                     /protein_id="YP_006099547.1"
                     /db_xref="GI:386598041"
                     /db_xref="GeneID:12688871"
                     /translation="MKKPLVIISACQFTRLALESLIPTDRYIVRVYSNVTTEVEFVLK
                     TSCGYLLADIPSLPSGELVLLACLARLRSDAGQWQVCLTGDSDWFDNAPAASLYNGFP
                     RIGTMLTASRYQNQIIRWLLRPLPGDMSDFWLLTARELSVLKILMQGMSFSEIARYEQ
                     RSSKTLHAIATRALMKLGLGTLSDFRLLYTGCGDSRVKRNIRLHAKYIGQHSAHRLTQ
                     YVQNMVSGILYPEKVAVGESINSDAISGKVLSGQRKNISKKRPGLL"
     misc_feature    complement(338309..>338446)
                     /locus_tag="ECOK1_0303"
                     /note="Response regulator containing a CheY-like receiver
                     domain and an HTH DNA-binding domain [Signal transduction
                     mechanisms / Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     misc_feature    complement(338291..338443)
                     /locus_tag="ECOK1_0303"
                     /note="helix_turn_helix, Lux Regulon; Region: HTH_LUXR;
                     smart00421"
                     /db_xref="CDD:197715"
     misc_feature    complement(order(338300..338302,338333..338347,
                     338351..338356,338360..338365,338387..338395,
                     338432..338440))
                     /locus_tag="ECOK1_0303"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(338294..338302,338393..338395,
                     338399..338401,338405..338407))
                     /locus_tag="ECOK1_0303"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            complement(339175..339738)
                     /locus_tag="ECOK1_0304"
                     /db_xref="GeneID:12688872"
     CDS             complement(339175..339738)
                     /locus_tag="ECOK1_0304"
                     /note="identified by match to protein family HMM PF00589"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase, phage integrase
                     family"
                     /protein_id="YP_006099548.1"
                     /db_xref="GI:386598042"
                     /db_xref="GeneID:12688872"
                     /translation="MTRKYLTQDEVYRLMDAAQSMSFPERNRCLIMMAFIHGFRASEL
                     LDLRLSDIDASGKQLNIRRIKNGFSTTHPLLPDEYNLIKLWLKQRKLIENGVEGDWLF
                     LSRKRRPISRQHFFSIIREAGKRAGLAVKAHPHMLRHACGFALADNGVDTRLLQDYLG
                     HRNIQHTVRYTASNAARFKGVWKKKPR"
     misc_feature    complement(339193..339732)
                     /locus_tag="ECOK1_0304"
                     /note="DNA breaking-rejoining enzymes, C-terminal
                     catalytic domain. The DNA breaking-rejoining enzyme
                     superfamily includes type IB topoisomerases and tyrosine
                     recombinases that share the same fold in their catalytic
                     domain containing six conserved active site...; Region:
                     DNA_BRE_C; cl00213"
                     /db_xref="CDD:260266"
     misc_feature    complement(order(339229..339231,339334..339342,
                     339544..339546,339616..339621))
                     /locus_tag="ECOK1_0304"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238231"
     misc_feature    complement(order(339229..339231,339256..339258,
                     339325..339327,339334..339336,339544..339546,
                     339619..339621))
                     /locus_tag="ECOK1_0304"
                     /note="Int/Topo IB signature motif; other site"
                     /db_xref="CDD:238231"
     misc_feature    complement(order(339229..339231,339256..339258,
                     339325..339327,339334..339336,339619..339621))
                     /locus_tag="ECOK1_0304"
                     /note="active site"
                     /db_xref="CDD:238231"
     gene            complement(340810..342498)
                     /gene="betA"
                     /locus_tag="ECOK1_0305"
                     /db_xref="GeneID:12688873"
     CDS             complement(340810..342498)
                     /gene="betA"
                     /locus_tag="ECOK1_0305"
                     /EC_number="1.1.99.1"
                     /note="identified by similarity to SP:P17444; match to
                     protein family HMM PF00732; match to protein family HMM
                     PF05199; match to protein family HMM TIGR01810"
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase"
                     /protein_id="YP_006099549.1"
                     /db_xref="GI:386598043"
                     /db_xref="GeneID:12688873"
                     /translation="MQFDYIIIGAGSAGNVLATRLTEDPNTTVLLLEAGGPDYRFDFR
                     TQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAL
                     DLDNWAQEPGLENWSYLDCLPYYRKAETRDVGENDYHGGDGPVSVTTSKPGVNPLFEA
                     MIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPHGRRASTARGYLDQAKSRPNLTIRT
                     HAMTDHIFFDGKRAVGVEWLEGDSTIPTRAAANKEVLLCAGAIASPQILQRSGVGNAE
                     LLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGG
                     TGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP
                     SRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISP
                     GVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMAVVDAEGRVHGLEGLRVVDASIM
                     PQIITGNLNATTIMIGEKMADMIRGKDALPRSTARYFVANGMPVRAKKMSRDVN"
     misc_feature    complement(340828..342498)
                     /gene="betA"
                     /locus_tag="ECOK1_0305"
                     /note="choline dehydrogenase; Validated; Region: PRK02106"
                     /db_xref="CDD:235000"
     misc_feature    complement(341596..342282)
                     /gene="betA"
                     /locus_tag="ECOK1_0305"
                     /note="GMC oxidoreductase; Region: GMC_oxred_N; pfam00732"
                     /db_xref="CDD:250093"
     misc_feature    complement(340924..341322)
                     /gene="betA"
                     /locus_tag="ECOK1_0305"
                     /note="GMC oxidoreductase; Region: GMC_oxred_C; pfam05199"
                     /db_xref="CDD:253079"
     gene            complement(342512..343984)
                     /gene="betB"
                     /locus_tag="ECOK1_0306"
                     /db_xref="GeneID:12688874"
     CDS             complement(342512..343984)
                     /gene="betB"
                     /locus_tag="ECOK1_0306"
                     /EC_number="1.2.1.8"
                     /note="identified by similarity to SP:P17445; match to
                     protein family HMM PF00171; match to protein family HMM
                     TIGR01804"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine aldehyde dehydrogenase"
                     /protein_id="YP_006099550.1"
                     /db_xref="GI:386598044"
                     /db_xref="GeneID:12688874"
                     /translation="MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGRE
                     DVDRAVKSAQQGQKIWAAMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETS
                     TVDIVTGADVLEYYAGLIPALEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIAL
                     WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTD
                     HPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADITMM
                     ANFFSSGQVCTNGTRVFVPTKCKAAFEQKILARVERIRAGDVFDPQTNFGPLVSFPHR
                     DNVLRYIAKGIEEGARVLCGGDVLKGDSFDNGAWVAPTVFTDCSDDMTIVREEIFGPV
                     MSILTYESEDEVIRRANDTDYGLAAGIVTADLNLAHRVIHQLEAGICWINTWGESPAE
                     MPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF"
     misc_feature    complement(342536..343909)
                     /gene="betB"
                     /locus_tag="ECOK1_0306"
                     /note="NAD+-dependent 4-trimethylaminobutyraldehyde
                     dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH;
                     cd07090"
                     /db_xref="CDD:143409"
     misc_feature    complement(order(342536..342541,342545..342562,
                     342596..342598,342602..342604,342611..342613,
                     342617..342619,342629..342631,342635..342637,
                     342659..342664,342668..342679,342683..342685,
                     342692..342694,342698..342703,342710..342721,
                     343013..343015,343058..343060,343157..343162,
                     343169..343171,343178..343180,343244..343246,
                     343280..343282,343562..343570,343574..343576,
                     343598..343612,343631..343633,343643..343645,
                     343745..343747,343754..343756,343766..343768,
                     343775..343777,343787..343789,343793..343795))
                     /gene="betB"
                     /locus_tag="ECOK1_0306"
                     /note="tetrameric interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:143409"
     misc_feature    complement(order(342626..342628,342818..342820,
                     342824..342826,343127..343129,343223..343231,
                     343286..343288,343295..343300,343304..343306,
                     343358..343360,343457..343459,343526..343531,
                     343535..343540))
                     /gene="betB"
                     /locus_tag="ECOK1_0306"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:143409"
     misc_feature    complement(order(343127..343129,343136..343138,
                     343229..343231,343526..343528))
                     /gene="betB"
                     /locus_tag="ECOK1_0306"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143409"
     gene            complement(343998..344585)
                     /gene="betI"
                     /locus_tag="ECOK1_0307"
                     /db_xref="GeneID:12688875"
     CDS             complement(343998..344585)
                     /gene="betI"
                     /locus_tag="ECOK1_0307"
                     /note="identified by similarity to SP:P17446; match to
                     protein family HMM PF00440; match to protein family HMM
                     TIGR03384"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor BetI"
                     /protein_id="YP_006099551.1"
                     /db_xref="GI:386598045"
                     /db_xref="GeneID:12688875"
                     /translation="MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTG
                     IISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAELRLQAIVGGNFDETQVS
                     SAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPRQQAQEAGYGLAAL
                     IDGLWLRAALSGKALDKPLAHSLTRHFITQHLPTD"
     misc_feature    complement(344004..344585)
                     /gene="betI"
                     /locus_tag="ECOK1_0307"
                     /note="transcriptional regulator BetI; Validated; Region:
                     PRK00767"
                     /db_xref="CDD:179115"
     misc_feature    complement(344409..344546)
                     /gene="betI"
                     /locus_tag="ECOK1_0307"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:249860"
     misc_feature    complement(344007..344327)
                     /gene="betI"
                     /locus_tag="ECOK1_0307"
                     /note="Bacterial transcriptional repressor; Region:
                     TetR_C_6; pfam13977"
                     /db_xref="CDD:258229"
     gene            344714..346747
                     /gene="betT"
                     /locus_tag="ECOK1_0308"
                     /db_xref="GeneID:12688876"
     CDS             344714..346747
                     /gene="betT"
                     /locus_tag="ECOK1_0308"
                     /note="identified by match to protein family HMM PF02028;
                     match to protein family HMM TIGR00842"
                     /codon_start=1
                     /transl_table=11
                     /product="transporter, betaine/carnitine/choline
                     transporter (BCCT) family"
                     /protein_id="YP_006099552.1"
                     /db_xref="GI:386598046"
                     /db_xref="GeneID:12688876"
                     /translation="MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIG
                     RTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFA
                     AGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
                     LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLN
                     YGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVL
                     FMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFV
                     GLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHP
                     ERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWL
                     RVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRE
                     SANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRG
                     AYVELKNLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYR
                     LETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDS"
     misc_feature    344714..346744
                     /gene="betT"
                     /locus_tag="ECOK1_0308"
                     /note="choline transport protein BetT; Provisional;
                     Region: PRK09928"
                     /db_xref="CDD:236635"
     gene            347625..348713
                     /locus_tag="ECOK1_0309"
                     /db_xref="GeneID:12688877"
     CDS             347625..348713
                     /locus_tag="ECOK1_0309"
                     /note="identified by match to protein family HMM PF00196;
                     match to protein family HMM PF00563"
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR-family transcriptional regulator/cyclic
                     diguanylate phosphodiesterase (EAL) domain protein"
                     /protein_id="YP_006099553.1"
                     /db_xref="GI:386598047"
                     /db_xref="GeneID:12688877"
                     /translation="MNSCDFRVFLQEFGTTVHLSLPGSVSEKERLLLKLLMQGMSVTE
                     ISQYRNRSAKTISHQKKQLFEKLGIQSDITFWRDIFFQYNPEIISATGNNSHKYINDN
                     HYHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGMIPPDQFI
                     PLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNL
                     VKKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQA
                     FPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKG
                     VHFLQGYLYSPPVPGNKFISEWVMKAGG"
     misc_feature    347700..347864
                     /locus_tag="ECOK1_0309"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    order(347700..347708,347745..347753,347775..347780,
                     347784..347789,347793..347807,347838..347840)
                     /locus_tag="ECOK1_0309"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    order(347733..347735,347739..347741,347745..347747,
                     347838..347846,347853..347855,347862..347864)
                     /locus_tag="ECOK1_0309"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     misc_feature    347955..348668
                     /locus_tag="ECOK1_0309"
                     /note="EAL domain. This domain is found in diverse
                     bacterial signaling proteins. It is called EAL after its
                     conserved residues and is also known as domain of unknown
                     function 2 (DUF2).  The EAL domain has been shown to
                     stimulate degradation of a second...; Region: EAL;
                     cd01948"
                     /db_xref="CDD:238923"
     gene            complement(348755..349687)
                     /locus_tag="ECOK1_0310"
                     /note="transcriptional regulator, LysR family; this gene
                     contains a frame shift which may be the result of a
                     sequencing error; identified by match to protein family
                     HMM PF00126; match to protein family HMM PF03466"
                     /pseudo
                     /db_xref="GeneID:12688878"
     gene            complement(349779..350276)
                     /locus_tag="ECOK1_0311"
                     /db_xref="GeneID:12688879"
     CDS             complement(349779..350276)
                     /locus_tag="ECOK1_0311"
                     /note="identified by similarity to GB:AAN78918.1; match to
                     protein family HMM PF06496"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099554.1"
                     /db_xref="GI:386598048"
                     /db_xref="GeneID:12688879"
                     /translation="MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCS
                     FYAAGGGKSGFIKSLAVNYSGMVWAFFAALAAGWLAPVSGLSAFWASVITTVPFSAVV
                     VWQGRFWLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGIISEYGGQKLSEATT
                     KSDGY"
     misc_feature    complement(349806..350252)
                     /locus_tag="ECOK1_0311"
                     /note="Protein of unknown function (DUF1097); Region:
                     DUF1097; pfam06496"
                     /db_xref="CDD:253770"
     gene            350534..351139
                     /locus_tag="ECOK1_0312"
                     /db_xref="GeneID:12688880"
     CDS             350534..351139
                     /locus_tag="ECOK1_0312"
                     /note="identified by match to protein family HMM PF00023"
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin"
                     /protein_id="YP_006099555.1"
                     /db_xref="GI:386598049"
                     /db_xref="GeneID:12688880"
                     /translation="MTIKNLPADYLLAAQQGDIDKVKICLALGVDINTCDRQGKTAIT
                     LASLYQQYACVQALIDAGANINKQDHTCLNPFLISCLNDDLTLLRIILPAKPDLNCVT
                     RFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
                     QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA"
     misc_feature    350567..350830
                     /locus_tag="ECOK1_0312"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:257303"
     misc_feature    <350567..350671
                     /locus_tag="ECOK1_0312"
                     /note="Ankyrin repeats (many copies); Region: Ank_5;
                     pfam13857"
                     /db_xref="CDD:258127"
     misc_feature    350630..351124
                     /locus_tag="ECOK1_0312"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:238125"
     misc_feature    350759..351055
                     /locus_tag="ECOK1_0312"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:257303"
     gene            351179..352042
                     /locus_tag="ECOK1_0313"
                     /db_xref="GeneID:12688881"
     CDS             351179..352042
                     /locus_tag="ECOK1_0313"
                     /note="identified by similarity to GB:AAZ87092.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099556.1"
                     /db_xref="GI:386598050"
                     /db_xref="GeneID:12688881"
                     /translation="MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
                     YDNAPNSCRLALTHFNGLFRHGDKVQFDDQGITVGQHLHIEMSHCQRWLSPTLQMTAL
                     NFHLIAWQQWHDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVNDKQNI
                     AVAVASMMGLGIGLTPSADDYLTGLALILFLPGHPAEKYKEEFYLGLQRGRNNTTLLS
                     AITLEAALQQRCRENIHRFIHNIIYDIPGNATQAIEKIKHIGSSSGCDMLYGMADGCA
                     LSQTYGGNYVS"
     misc_feature    351677..352009
                     /locus_tag="ECOK1_0313"
                     /note="Protein of unknown function (DUF2877); Region:
                     DUF2877; pfam11392"
                     /db_xref="CDD:256444"
     gene            352032..353579
                     /locus_tag="ECOK1_0314"
                     /db_xref="GeneID:12688882"
     CDS             352032..353579
                     /locus_tag="ECOK1_0314"
                     /note="identified by match to protein family HMM PF06263"
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial FdrA protein"
                     /protein_id="YP_006099557.1"
                     /db_xref="GI:386598051"
                     /db_xref="GeneID:12688882"
                     /translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
                     GVLKNLGLLTPELEQAKNGDLMIVINGKSGVDNEQLLAEIEELFNTKAQSGSHEARYA
                     TIASAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
                     EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
                     LIGTGGRDLSEKIGGLMMLDAIGMLENDPQTEIIVLISKPPAPAVARKVLERARACRK
                     PVVACFLGRGETPVDEQGLQFARGSKEAALKAVMLSGVKQEHLDLHTLNQPLIADVRA
                     RLQPQQKYIRGLFCGGTLCDETLFAVMEKHGDVYSNIQPDPEFRLQDINRSIKHTFLD
                     FGDDDFTNGKPHPMIDPTNRISRVIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIEAI
                     KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
                     ICKGEEA"
     misc_feature    352086..353147
                     /locus_tag="ECOK1_0314"
                     /note="Succinyl-CoA synthetase, alpha subunit [Energy
                     production and conversion]; Region: SucD; COG0074"
                     /db_xref="CDD:223152"
     misc_feature    352590..352883
                     /locus_tag="ECOK1_0314"
                     /note="CoA binding domain; Region: CoA_binding; pfam02629"
                     /db_xref="CDD:251432"
     misc_feature    353067..353546
                     /locus_tag="ECOK1_0314"
                     /note="CoA-ligase; Region: Ligase_CoA; pfam00549"
                     /db_xref="CDD:249950"
     gene            353579..354997
                     /locus_tag="ECOK1_0315"
                     /db_xref="GeneID:12688883"
     CDS             353579..354997
                     /locus_tag="ECOK1_0315"
                     /note="identified by match to protein family HMM PF06545"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099558.1"
                     /db_xref="GI:386598052"
                     /db_xref="GeneID:12688883"
                     /translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQLDWTPPGQGNM
                     QVVQALDNIADSPLADKIASANQQALERIIQSHPVLIGFDQAINVVPGMTAKTILHAG
                     PPVTWEKMCGAMKGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGV
                     TSASMFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPMLRDA
                     MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVEQQREVFEF
                     VASCDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
                     QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
                     QMREITLGENPNVTIPLLGFMGVPSAIDITRVGSSGILPVINTAIAHKDAGIGMIGAG
                     IVHPPFACFEKAIFGWCERYGV"
     misc_feature    354005..354652
                     /locus_tag="ECOK1_0315"
                     /note="Protein of unknown function (DUF1116); Region:
                     DUF1116; pfam06545"
                     /db_xref="CDD:148259"
     gene            355151..356101
                     /locus_tag="ECOK1_0316"
                     /db_xref="GeneID:12688884"
     CDS             355151..356101
                     /locus_tag="ECOK1_0316"
                     /note="identified by match to protein family HMM PF00696"
                     /codon_start=1
                     /transl_table=11
                     /product="putative carbamate kinase"
                     /protein_id="YP_006099559.1"
                     /db_xref="GI:386598053"
                     /db_xref="GeneID:12688884"
                     /translation="MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASD
                     YDIVLTHGNGPQVGLDLRRAEIAHEREGLPLTPLANCVADTQGGIGYLIQQALNNRLA
                     RHGEKKAVTVVTQVEVDKNDPGFAHPIKPIGAFFSESQRDELQKANPDWRFVEDAGRG
                     YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTDAGDYQSVDAVIDKDL
                     STALLAREIHADILVITTGVEKVCIHFGKPQQQALDRVDIATMTRYMQEGHFPPGSML
                     PKIIASLTFLEQGGKEVIITTPECLPAALRGETGTHIIKT"
     misc_feature    355160..356092
                     /locus_tag="ECOK1_0316"
                     /note="AAK_CK: Carbamate kinase (CK) catalyzes both the
                     ATP-phosphorylation of carbamate and carbamoyl phosphate
                     (CP) utilization with the production of ATP from ADP and
                     CP. Both CK (this CD) and nonhomologous CP synthetase
                     synthesize carbamoyl phosphate, an...; Region: AAK_CK;
                     cd04235"
                     /db_xref="CDD:239768"
     misc_feature    order(355172..355174,355178..355183,355304..355312,
                     355538..355540,355793..355801)
                     /locus_tag="ECOK1_0316"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:239768"
     misc_feature    order(355181..355183,355856..355861,355874..355876,
                     355883..355885,355958..355960,355970..355975,
                     355982..355984)
                     /locus_tag="ECOK1_0316"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239768"
     misc_feature    order(355181..355183,355856..355861,355874..355876,
                     355883..355885,355958..355960,355970..355975,
                     355982..355984)
                     /locus_tag="ECOK1_0316"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239768"
     misc_feature    order(355334..355336,355376..355378,355385..355390,
                     355397..355399,355409..355414,355421..355423,
                     355430..355435,355445..355447,355481..355489,
                     355493..355495,355673..355675,355682..355684,
                     355769..355771,355775..355777)
                     /locus_tag="ECOK1_0316"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239768"
     gene            356249..357493
                     /locus_tag="ECOK1_0317"
                     /db_xref="GeneID:12688885"
     CDS             356249..357493
                     /locus_tag="ECOK1_0317"
                     /note="identified by match to protein family HMM PF07969"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="YP_006099560.1"
                     /db_xref="GI:386598054"
                     /db_xref="GeneID:12688885"
                     /translation="MKITDPYYYLDNVLLETGFDYENGVAVQTRTARQTVEIQNGKIV
                     ALRENKQHPDATLPHYDAGGKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMI
                     KLEQKMLPELQPYTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARR
                     QAGFECEIVAFPQHGLLLSKSEPLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQI
                     ALDYDKGVDIHLHETTPAGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDE
                     LAHRMAAQQISIASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKA
                     NLYAQLYIRPNEQNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAV
                     ARISPRTATFHKGQLVWGSVAG"
     misc_feature    356273..357472
                     /locus_tag="ECOK1_0317"
                     /note="Bacterial cytosine deaminase and related
                     metal-dependent hydrolases. Cytosine deaminases (CDs)
                     catalyze the deamination of cytosine, producing uracil and
                     ammonia. They play an important role in pyrimidine
                     salvage. CDs are present in prokaryotes and fungi; Region:
                     Bact_CD; cd01293"
                     /db_xref="CDD:238618"
     misc_feature    356342..357472
                     /locus_tag="ECOK1_0317"
                     /note="cytosine deaminase; Provisional; Region: PRK05985"
                     /db_xref="CDD:180337"
     misc_feature    order(356471..356473,356477..356479,356933..356935,
                     356942..356944,357032..357034,357194..357196)
                     /locus_tag="ECOK1_0317"
                     /note="active site"
                     /db_xref="CDD:238618"
     gene            357761..358201
                     /locus_tag="ECOK1_0318"
                     /db_xref="GeneID:12688886"
     CDS             357761..358201
                     /locus_tag="ECOK1_0318"
                     /note="identified by similarity to GB:AAV79770.1; match to
                     protein family HMM PF04266"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099561.1"
                     /db_xref="GI:386598055"
                     /db_xref="GeneID:12688886"
                     /translation="MFFRNRENILMTIKEKISQKYPHASFCTFGDSAALADHLATLIA
                     TGVKTASCGSLAGCIEDNAFPMIGEYKIVENSRGEPVCVIRVIGLHLLRFSDVTAELA
                     RKEGEGDLSLEYWRNEHRRFFQAEGCYSPEMDVIFEEYALIDVV"
     misc_feature    357830..358192
                     /locus_tag="ECOK1_0318"
                     /note="ASC-1 homology domain, subfamily similar to
                     Enterococcus faecalis Ef3133. The ASCH domain, a small
                     beta-barrel domain found in all three kingdoms of life,
                     resembles the RNA-binding PUA domain and may also interact
                     with RNA. ASCH has been proposed to...; Region:
                     ASCH_Ef3133_like; cd06553"
                     /db_xref="CDD:119345"
     gene            358455..359438
                     /locus_tag="ECOK1_0319"
                     /db_xref="GeneID:12688887"
     CDS             358455..359438
                     /locus_tag="ECOK1_0319"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter periplasmic
                     substrate-binding protein"
                     /protein_id="YP_006099562.1"
                     /db_xref="GI:386598056"
                     /db_xref="GeneID:12688887"
                     /translation="MNKRFVINMVSSLLLGAALISAPLQAAEKVVVNISKVDGMPWFN
                     RMGEGVVEAGKAFGVNASQVGPSSTDAPQQVKIIEDLIARKVNAITIVPNDANVLEPV
                     FKKARDAGIVVLTNESPGQPSANWDIEIIDNEKFAAEYVEHMAKRMGGKGGYVIYVGS
                     LTVPQHNLWADLLVKYQKEHYPDMHEVTRRMPVAESVDDSRRTTLDLMKTYPDLKAVV
                     SFGSNGPIGAGRAVKEKRAKNKVAVYGMMIPSQAASLIKSGDITEGITYDPASAGYAL
                     AAVASTLLKGEEIKPGLEMQNLGKADVDMDKRIIRFHKVLLVNKDNIDSLY"
     misc_feature    358542..359426
                     /locus_tag="ECOK1_0319"
                     /note="Periplasmic binding domain of autoinducer-2 (AI-2)
                     receptor LsrB from Salmonella typhimurium and its close
                     homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302"
                     /db_xref="CDD:107297"
     misc_feature    358545..359318
                     /locus_tag="ECOK1_0319"
                     /note="Periplasmic binding protein domain; Region:
                     Peripla_BP_4; pfam13407"
                     /db_xref="CDD:257732"
     misc_feature    order(358560..358562,358803..358805,358842..358844,
                     358947..358952,358959..358961,359112..359120,
                     359253..359255)
                     /locus_tag="ECOK1_0319"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107297"
     gene            359487..360971
                     /locus_tag="ECOK1_0320"
                     /db_xref="GeneID:12688888"
     CDS             359487..360971
                     /locus_tag="ECOK1_0320"
                     /note="identified by match to protein family HMM PF00005"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="YP_006099563.1"
                     /db_xref="GI:386598057"
                     /db_xref="GeneID:12688888"
                     /translation="METFLSLRHINKTFHATRALRDVSLDFMSGEVHCLAGQNGCGKS
                     TLIKIMSGVYRPDEGAEITLGGKNWSKLTPAASVAQGIQVIYQDLSLFPNLSVWENIA
                     VNHYHHGLFVNRRRLREVAQAAMTSINVTLPLDTLVSELSIARCQLVAICRALAQDAR
                     LIVMDEPTASLTHQEVQGLLQVVHQLRERGICVVFVSHRLEEVMEVSDRISVLKDGEL
                     VGTFPAAEMTTKQLGFLMTGQEFEYQVRELWQGKSSTPVLEVRNLSRHGEYLNINLRV
                     EAGEVVSIVGLLGAGRTELCLSLFGMTRPDAGEILINGQLVTLHSNQDAIRHGIGYVS
                     EDRMSRGLVMAQSIEDNIISTVFHKVKDRFGFLSEAKVCDLVDRLIKALTIKVSDPHL
                     PVNTLSGGNAQRVSIAKWLAIGPRLLILDSPTVGVDIANKAGIYGIISDLAAHGIAVL
                     MICDEIEEAWYQSHRILVMQKGQITHSFLPDSSSQARIAEVVNG"
     misc_feature    359487..360968
                     /locus_tag="ECOK1_0320"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    359499..360149
                     /locus_tag="ECOK1_0320"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    359595..359618
                     /locus_tag="ECOK1_0320"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(359604..359609,359613..359621,359745..359747,
                     359979..359984,360078..360080)
                     /locus_tag="ECOK1_0320"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    359736..359747
                     /locus_tag="ECOK1_0320"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    359907..359936
                     /locus_tag="ECOK1_0320"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    359967..359984
                     /locus_tag="ECOK1_0320"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    359991..360002
                     /locus_tag="ECOK1_0320"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    360066..360086
                     /locus_tag="ECOK1_0320"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    360252..360908
                     /locus_tag="ECOK1_0320"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            360964..361935
                     /locus_tag="ECOK1_0321"
                     /db_xref="GeneID:12688889"
     CDS             360964..361935
                     /locus_tag="ECOK1_0321"
                     /note="identified by match to protein family HMM PF02653"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="YP_006099564.1"
                     /db_xref="GI:386598058"
                     /db_xref="GeneID:12688889"
                     /translation="MAELKKRHEFWLALLIVVLFVGLAWRSDEFLTFGNLYDLANNYA
                     MLTILACGLFVVLISGGIDISFPAMTIIAQYGMVLLLQKIGGNFAVAFALAGGIGILL
                     GLINALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEQGVMLFKYTDA
                     DGYDYGLGLPLIAMITVVLLTAFIMNFTSVGRKIYALGGNRESASRIGFSVLKLQLFV
                     YGYMGLMSGAAGVVQSWTVMTVAPDSLLGYELTVLAAVVLGGTSLLGGRGTLTGTLLG
                     VVLLAVMQNGLNLLGVSSYWQTLITGIIIVASISATAWSQHQNRSLL"
     misc_feature    361093..361899
                     /locus_tag="ECOK1_0321"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    361567..361623
                     /locus_tag="ECOK1_0321"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            361932..362888
                     /locus_tag="ECOK1_0322"
                     /db_xref="GeneID:12688890"
     CDS             361932..362888
                     /locus_tag="ECOK1_0322"
                     /note="identified by match to protein family HMM PF02653"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="YP_006099565.1"
                     /db_xref="GI:386598059"
                     /db_xref="GeneID:12688890"
                     /translation="MKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQ
                     MPVLGILALAMAVTMLCGGINLSIIATANACSLVMAWVATQYPPGIATVVATLLAGAG
                     AAVIIGLCNGVLIAGIRVSPILATLGMMTLLKGVNILVTGGSAIANYPSWVLWLNHAQ
                     WFGIPLPMWLFTAVALGLWILLEKTPLGKSIYLIGSNERATLYSGINTRRVLIWVYVI
                     SALLCAVAAFLMMSKLNSAKASYGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFL
                     LQIIESGFNILGISPYLTMALWGTLLLCFIQARGMLGLDRVV"
     misc_feature    362064..362849
                     /locus_tag="ECOK1_0322"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    362526..362582
                     /locus_tag="ECOK1_0322"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            362975..364024
                     /locus_tag="ECOK1_0323"
                     /db_xref="GeneID:12688891"
     CDS             362975..364024
                     /locus_tag="ECOK1_0323"
                     /note="identified by match to protein family HMM PF00107;
                     match to protein family HMM PF08240"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase, zinc-binding dehydrogenase
                     family"
                     /protein_id="YP_006099566.1"
                     /db_xref="GI:386598060"
                     /db_xref="GeneID:12688891"
                     /translation="MKIKAVGAYSAKQPLEPMDITRREPGPHDVKIEIAYCGVCHSDI
                     HQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDG
                     LENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
                     ITTYSPLRHWLAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSESKREAAKALG
                     ADEVVNSRNADEMVAHVKSFDFILNTVAAPHNLDDFTTLLKRDGTITLVGAPATPHKS
                     PEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRG
                     DVKYRFVIDNRTLTD"
     misc_feature    362975..364012
                     /locus_tag="ECOK1_0323"
                     /note="Zn-dependent alcohol dehydrogenases [General
                     function prediction only]; Region: AdhP; COG1064"
                     /db_xref="CDD:223992"
     misc_feature    362984..364003
                     /locus_tag="ECOK1_0323"
                     /note="Cinnamyl alcohol dehydrogenases (CAD); Region:
                     CAD1; cd05283"
                     /db_xref="CDD:176186"
     misc_feature    order(363092..363100,363107..363109,363446..363448,
                     363458..363460,363518..363535,363587..363592,
                     363602..363604,363647..363649,363704..363709,
                     363713..363715,363773..363778,363848..363856)
                     /locus_tag="ECOK1_0323"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:176186"
     misc_feature    order(363092..363094,363098..363100,363158..363160,
                     363236..363238,363446..363448,363854..363856)
                     /locus_tag="ECOK1_0323"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:176186"
     misc_feature    order(363092..363094,363158..363160,363446..363448)
                     /locus_tag="ECOK1_0323"
                     /note="catalytic Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176186"
     misc_feature    order(363251..363253,363260..363262,363269..363271,
                     363293..363295)
                     /locus_tag="ECOK1_0323"
                     /note="structural Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176186"
     misc_feature    order(363290..363292,363467..363469,363479..363481,
                     363755..363757,363770..363778,363782..363784,
                     363812..363814,363818..363823,363830..363853)
                     /locus_tag="ECOK1_0323"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:176186"
     gene            364576..364656
                     /locus_tag="ECOK1_0324"
                     /pseudo
                     /db_xref="GeneID:12688892"
     tRNA            364576..364656
                     /locus_tag="ECOK1_0324"
                     /product="tRNA-OTHER"
                     /note="tRNA-Pseudo"
                     /pseudo
                     /db_xref="GeneID:12688892"
     gene            complement(364908..365576)
                     /locus_tag="ECOK1_0325"
                     /db_xref="GeneID:12688893"
     CDS             complement(364908..365576)
                     /locus_tag="ECOK1_0325"
                     /note="identified by match to protein family HMM PF01810;
                     match to protein family HMM TIGR00949"
                     /codon_start=1
                     /transl_table=11
                     /product="putative homoserine/threonine efflux protein"
                     /protein_id="YP_006099567.1"
                     /db_xref="GI:386598061"
                     /db_xref="GeneID:12688893"
                     /translation="MKLLHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQTS
                     LASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAWC
                     SMRRQSTPQMSTLQQPISAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTWA
                     RLMAWAGIVLASIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYEG
                     VTQR"
     misc_feature    complement(364935..365483)
                     /locus_tag="ECOK1_0325"
                     /note="The Resistance to Homoserine/Threonine (RhtB)
                     Family protein; Region: 2A76; TIGR00949"
                     /db_xref="CDD:233204"
     STS             365697..366331
                     /standard_name="D14S163"
                     /db_xref="UniSTS:148387"
     gene            365726..366001
                     /locus_tag="ECOK1_0326"
                     /db_xref="GeneID:12688894"
     CDS             365726..366001
                     /locus_tag="ECOK1_0326"
                     /note="identified by match to protein family HMM PF07338"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099568.1"
                     /db_xref="GI:386598062"
                     /db_xref="GeneID:12688894"
                     /translation="MKIISKMLVGALAFAVTNVYAAELMTKAEFEKVESQYEKIGDIS
                     TSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK"
     misc_feature    365726..365998
                     /locus_tag="ECOK1_0326"
                     /note="hypothetical protein; Provisional; Region:
                     PRK09929"
                     /db_xref="CDD:182151"
     gene            complement(366102..367688)
                     /locus_tag="ECOK1_0327"
                     /note="propionate catabolism operon regulatory protein
                     PrpR, authentic frameshift; this gene contains a premature
                     stop which is not the result of sequencing error"
                     /pseudo
                     /db_xref="GeneID:12688895"
     gene            367927..368817
                     /gene="prpB"
                     /locus_tag="ECOK1_0328"
                     /db_xref="GeneID:12688896"
     CDS             367927..368817
                     /gene="prpB"
                     /locus_tag="ECOK1_0328"
                     /EC_number="4.1.3.30"
                     /note="identified by match to protein family HMM
                     TIGR02317"
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="YP_006099569.1"
                     /db_xref="GI:386598063"
                     /db_xref="GeneID:12688896"
                     /translation="MSLHSPGKAFRAALSKENPLQIVGTINANHALLAQRAGYQAIYL
                     SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVK
                     SMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
                     ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATP
                     LFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYES
                     INYYQYEEKLDDLFARNQAK"
     misc_feature    367954..368679
                     /gene="prpB"
                     /locus_tag="ECOK1_0328"
                     /note="Members of the ICL/PEPM enzyme family catalyze
                     either P-C or C-C bond formation/cleavage. Known members
                     are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate
                     hydrolase (PPH), carboxyPEP mutase (CPEP mutase),
                     oxaloacetate hydrolase (OAH), isocitrate...; Region:
                     ICL_PEPM; cd00377"
                     /db_xref="CDD:119340"
     misc_feature    order(367960..367962,367981..367983,367987..367998,
                     368002..368016,368020..368025,368032..368034,
                     368038..368046,368065..368067,368077..368079,
                     368083..368085,368092..368097,368104..368115,
                     368119..368124,368131..368136,368140..368145,
                     368152..368157,368197..368199,368218..368223,
                     368233..368235,368242..368244,368329..368334,
                     368341..368343,368350..368355,368362..368364,
                     368650..368658,368662..368670,368674..368679)
                     /gene="prpB"
                     /locus_tag="ECOK1_0328"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:119340"
     misc_feature    order(368053..368055,368059..368067,368098..368100,
                     368179..368181,368185..368187,368269..368271,
                     368398..368400,368488..368490,368554..368556,
                     368560..368562,368632..368634)
                     /gene="prpB"
                     /locus_tag="ECOK1_0328"
                     /note="active site"
                     /db_xref="CDD:119340"
     misc_feature    order(368098..368100,368179..368181,368185..368187,
                     368269..368271)
                     /gene="prpB"
                     /locus_tag="ECOK1_0328"
                     /note="Mg2+/Mn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:119340"
     gene            368862..370031
                     /gene="prpC"
                     /locus_tag="ECOK1_0329"
                     /db_xref="GeneID:12688897"
     CDS             368862..370031
                     /gene="prpC"
                     /locus_tag="ECOK1_0329"
                     /EC_number="2.3.3.5"
                     /note="identified by similarity to SP:P31660; match to
                     protein family HMM PF00285; match to protein family HMM
                     TIGR01800"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="YP_006099570.1"
                     /db_xref="GI:386598064"
                     /db_xref="GeneID:12688897"
                     /translation="MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAAHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPSPSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     MYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNM
                     MGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRQFVALDKRQ"
     misc_feature    368889..370025
                     /gene="prpC"
                     /locus_tag="ECOK1_0329"
                     /note="Citrate synthase [Energy production and
                     conversion]; Region: GltA; COG0372"
                     /db_xref="CDD:223449"
     misc_feature    368919..370016
                     /gene="prpC"
                     /locus_tag="ECOK1_0329"
                     /note="Subgroup of Escherichia coli (Ec) 2-methylcitrate
                     synthase (2MCS)_like. 2MCS catalyzes the condensation of
                     propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form
                     2-methylcitrate and coenzyme A (CoA) during propionate
                     metabolism. Citrate synthase (CS)...; Region:
                     Ec2MCS_like_1; cd06117"
                     /db_xref="CDD:99870"
     misc_feature    order(368919..368927,368934..368948,369132..369137,
                     369144..369149,369171..369173,369183..369185,
                     369195..369197,369204..369206,369348..369350,
                     369459..369473,369480..369485,369495..369497,
                     369504..369515,369522..369524,369543..369548,
                     369552..369563,369684..369686,369957..369989)
                     /gene="prpC"
                     /locus_tag="ECOK1_0329"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:99870"
     misc_feature    order(368928..368930,369459..369461,369468..369470,
                     369561..369569,369573..369575,369582..369584,
                     369663..369686,369693..369695,369708..369710,
                     369813..369815,369819..369821,369828..369830,
                     369834..369836,369897..369899,369909..369911,
                     369957..369959,369966..369968)
                     /gene="prpC"
                     /locus_tag="ECOK1_0329"
                     /note="active site"
                     /db_xref="CDD:99870"
     misc_feature    order(368928..368930,369459..369461,369468..369470,
                     369561..369566,369663..369668,369672..369686,
                     369708..369710,369828..369830,369909..369911)
                     /gene="prpC"
                     /locus_tag="ECOK1_0329"
                     /note="citrylCoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99870"
     misc_feature    order(369459..369461,369468..369470,369564..369569,
                     369681..369683,369708..369710,369834..369836,
                     369897..369899,369909..369911,369966..369968)
                     /gene="prpC"
                     /locus_tag="ECOK1_0329"
                     /note="oxalacetate/citrate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99870"
     misc_feature    order(369561..369566,369573..369575,369582..369584,
                     369663..369680,369684..369686,369693..369695,
                     369813..369815,369819..369821,369828..369830,
                     369834..369836,369957..369959)
                     /gene="prpC"
                     /locus_tag="ECOK1_0329"
                     /note="coenzyme A binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99870"
     misc_feature    order(369564..369566,369681..369683,369834..369836)
                     /gene="prpC"
                     /locus_tag="ECOK1_0329"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:99870"
     gene            370065..371516
                     /gene="prpD"
                     /locus_tag="ECOK1_0330"
                     /db_xref="GeneID:12688898"
     CDS             370065..371516
                     /gene="prpD"
                     /locus_tag="ECOK1_0330"
                     /EC_number="4.2.1.79"
                     /note="identified by match to protein family HMM PF03972;
                     match to protein family HMM TIGR02330"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate dehydratase"
                     /protein_id="YP_006099571.1"
                     /db_xref="GI:386598065"
                     /db_xref="GeneID:12688898"
                     /translation="MSAQINNIRPEFDREIVDIVDYVMNYEISSRVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAIASGKAPLTMKQVLTGMIKAHEIQGCIAL
                     ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDK
                     KGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPAFT
                     ADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQ
                     FPTRQQQRILEVSLDRTRLEQMPVNEYLDLYVI"
     misc_feature    370065..371513
                     /gene="prpD"
                     /locus_tag="ECOK1_0330"
                     /note="2-methylcitrate dehydratase; Provisional; Region:
                     prpD; PRK09425"
                     /db_xref="CDD:181845"
     gene            371556..373442
                     /gene="prpE"
                     /locus_tag="ECOK1_0331"
                     /db_xref="GeneID:12688899"
     CDS             371556..373442
                     /gene="prpE"
                     /locus_tag="ECOK1_0331"
                     /EC_number="6.2.1.17"
                     /note="identified by match to protein family HMM PF00501;
                     match to protein family HMM TIGR02316"
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="YP_006099572.1"
                     /db_xref="GI:386598066"
                     /db_xref="GeneID:12688899"
                     /translation="MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFAR
                     WFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRS
                     LGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
                     SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQ
                     HIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAP
                     TAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESG
                     WPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGC
                     IQTIWGDDDRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTR
                     EIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDREVAHLQEKAIMALV
                     DSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQ
                     AMEE"
     misc_feature    371556..373439
                     /gene="prpE"
                     /locus_tag="ECOK1_0331"
                     /note="propionyl-CoA synthetase; Provisional; Region:
                     prpE; PRK10524"
                     /db_xref="CDD:182517"
     misc_feature    371589..373421
                     /gene="prpE"
                     /locus_tag="ECOK1_0331"
                     /note="Adenylate forming domain, Class I; Region:
                     AFD_class_I; cl17068"
                     /db_xref="CDD:266508"
     misc_feature    order(372264..372266,372273..372290,372294..372299)
                     /gene="prpE"
                     /locus_tag="ECOK1_0331"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213270"
     misc_feature    order(372273..372275,372639..372644,372705..372722,
                     372987..372989,373023..373025,373032..373034,
                     373065..373067,373329..373331)
                     /gene="prpE"
                     /locus_tag="ECOK1_0331"
                     /note="AMP binding site [chemical binding]; other site"
                     /db_xref="CDD:213270"
     misc_feature    order(372273..372275,372396..372401,372552..372554,
                     372558..372563,372570..372572,372639..372644,
                     372705..372722,372987..372989,373023..373025,
                     373032..373034,373056..373067,373272..373274)
                     /gene="prpE"
                     /locus_tag="ECOK1_0331"
                     /note="active site"
                     /db_xref="CDD:213270"
     misc_feature    order(372396..372398,372558..372563,372570..372572,
                     372639..372641,373056..373064,373254..373256,
                     373272..373274)
                     /gene="prpE"
                     /locus_tag="ECOK1_0331"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:213270"
     gene            373767..375026
                     /gene="codB"
                     /locus_tag="ECOK1_0332"
                     /db_xref="GeneID:12688900"
     CDS             373767..375026
                     /gene="codB"
                     /locus_tag="ECOK1_0332"
                     /note="identified by similarity to SP:P0AA82; match to
                     protein family HMM PF02133; match to protein family HMM
                     TIGR00800"
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="YP_006099573.1"
                     /db_xref="GI:386598067"
                     /db_xref="GeneID:12688900"
                     /translation="MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG
                     TGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLG
                     GTQVGWFGVGVAMFSIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSVIAVPA
                     IACLGGYSVWLAVNGMGGLDVLKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFG
                     RNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPP
                     VGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGA
                     LSYLILNPILNRKTTAAMTHVEANSVE"
     misc_feature    373773..374978
                     /gene="codB"
                     /locus_tag="ECOK1_0332"
                     /note="nucleobase-cation-symport-1 (NCS1) transporter
                     CobB-like; solute-binding domain; Region:
                     SLC-NCS1sbd_CobB-like; cd11484"
                     /db_xref="CDD:212053"
     misc_feature    order(373851..373853,373860..373862,374589..374591,
                     374598..374603)
                     /gene="codB"
                     /locus_tag="ECOK1_0332"
                     /note="Na binding site [ion binding]; other site"
                     /db_xref="CDD:212053"
     misc_feature    order(373863..373865,374088..374090,374100..374102,
                     374373..374378,374382..374384,374604..374606,
                     374616..374618)
                     /gene="codB"
                     /locus_tag="ECOK1_0332"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:212053"
     gene            375016..376299
                     /gene="codA"
                     /locus_tag="ECOK1_0333"
                     /db_xref="GeneID:12688901"
     CDS             375016..376299
                     /gene="codA"
                     /locus_tag="ECOK1_0333"
                     /EC_number="3.5.4.1"
                     /note="identified by similarity to SP:P25524; match to
                     protein family HMM PF01979; match to protein family HMM
                     PF07969"
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine deaminase"
                     /protein_id="YP_006099574.1"
                     /db_xref="GI:386598068"
                     /db_xref="GeneID:12688901"
                     /translation="MSNNALQTIINAQLPGKEGLWQIHLHDGKISAIDAQSGVMPVTE
                     NSLDAEQGLVLPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVK
                     QRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGI
                     LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDE
                     IDDEQSRFVETVAALAHREGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVAN
                     PLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHM
                     GLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQ
                     VPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR"
     misc_feature    375034..376269
                     /gene="codA"
                     /locus_tag="ECOK1_0333"
                     /note="Cytosine deaminase and related metal-dependent
                     hydrolases [Nucleotide transport and metabolism / General
                     function prediction only]; Region: SsnA; COG0402"
                     /db_xref="CDD:223479"
     misc_feature    375037..376230
                     /gene="codA"
                     /locus_tag="ECOK1_0333"
                     /note="Bacterial cytosine deaminase and related
                     metal-dependent hydrolases. Cytosine deaminases (CDs)
                     catalyze the deamination of cytosine, producing uracil and
                     ammonia. They play an important role in pyrimidine
                     salvage. CDs are present in prokaryotes and fungi; Region:
                     Bact_CD; cd01293"
                     /db_xref="CDD:238618"
     misc_feature    order(375199..375201,375205..375207,375658..375660,
                     375667..375669,375754..375756,375955..375957)
                     /gene="codA"
                     /locus_tag="ECOK1_0333"
                     /note="active site"
                     /db_xref="CDD:238618"
     gene            complement(376420..377031)
                     /locus_tag="ECOK1_0334"
                     /db_xref="GeneID:12688902"
     CDS             complement(376420..377031)
                     /locus_tag="ECOK1_0334"
                     /note="identified by match to protein family HMM PF00132"
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="YP_006099575.1"
                     /db_xref="GI:386598069"
                     /db_xref="GeneID:12688902"
                     /translation="MNMSMTERIKAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEV
                     DKRESLIKEMFATVGENAWVEPPVYFSYGSNIYIGRNFYANFNLTIVDDYTVTIGDNV
                     LIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGA
                     GSVVTKDIPPNVVAAGVPCRVIREINDRDKQYYFKDFKVESSV"
     misc_feature    complement(376423..377031)
                     /locus_tag="ECOK1_0334"
                     /note="galactoside O-acetyltransferase; Reviewed; Region:
                     lacA; PRK09527"
                     /db_xref="CDD:181930"
     misc_feature    complement(376486..376992)
                     /locus_tag="ECOK1_0334"
                     /note="Maltose O-acetyltransferase (MAT) and Galactoside
                     O-acetyltransferase (GAT): MAT and GAT catalyze the
                     CoA-dependent acetylation of the 6-hydroxyl group of their
                     respective sugar substrates. MAT acetylates maltose and
                     glucose exclusively at the C6...; Region: LbH_MAT_GAT;
                     cd03357"
                     /db_xref="CDD:100047"
     misc_feature    complement(order(376492..376494,376498..376509,
                     376534..376539,376543..376545,376552..376557,
                     376591..376593,376606..376611,376615..376617,
                     376651..376653,376657..376662,376681..376683,
                     376687..376689,376693..376695,376699..376701,
                     376717..376719,376723..376725,376753..376755,
                     376759..376761,376777..376779,376783..376785,
                     376819..376821,376954..376956,376981..376983))
                     /locus_tag="ECOK1_0334"
                     /note="active site"
                     /db_xref="CDD:100047"
     misc_feature    complement(order(376651..376653,376657..376662,
                     376687..376689,376693..376695,376723..376725,
                     376753..376755,376759..376761,376777..376779,
                     376783..376785,376819..376821,376954..376956,
                     376981..376983))
                     /locus_tag="ECOK1_0334"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100047"
     misc_feature    complement(order(376501..376503,376537..376539,
                     376549..376554,376561..376563,376567..376569,
                     376591..376593,376600..376608,376615..376617,
                     376621..376623,376642..376644,376648..376650,
                     376666..376671,376675..376683,376687..376689,
                     376699..376701,376705..376707,376711..376713,
                     376723..376725,376729..376731,376771..376776,
                     376822..376827,376831..376833,376909..376911,
                     376930..376932,376942..376944,376951..376953))
                     /locus_tag="ECOK1_0334"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:100047"
     misc_feature    complement(order(376498..376500,376504..376509,
                     376534..376539,376552..376557,376591..376593,
                     376606..376611,376615..376617,376681..376683,
                     376687..376689,376693..376695,376699..376701))
                     /locus_tag="ECOK1_0334"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:100047"
     gene            complement(377097..378350)
                     /gene="lacY"
                     /locus_tag="ECOK1_0335"
                     /db_xref="GeneID:12688903"
     CDS             complement(377097..378350)
                     /gene="lacY"
                     /locus_tag="ECOK1_0335"
                     /note="identified by similarity to SP:P02920; match to
                     protein family HMM PF01306; match to protein family HMM
                     PF07690; match to protein family HMM TIGR00882"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose permease"
                     /protein_id="YP_006099576.1"
                     /db_xref="GI:386598070"
                     /db_xref="GeneID:12688903"
                     /translation="MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSD
                     TGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYN
                     ILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGI
                     MFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFR
                     QPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIM
                     FFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCF
                     KYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGF
                     TLISVFTLSGPGPLSLLRRQVNEVA"
     misc_feature    complement(377112..378350)
                     /gene="lacY"
                     /locus_tag="ECOK1_0335"
                     /note="LacY proton/sugar symporter; Region: LacY_symp;
                     pfam01306"
                     /db_xref="CDD:110319"
     misc_feature    complement(377157..378284)
                     /gene="lacY"
                     /locus_tag="ECOK1_0335"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(order(377265..377267,377274..377276,
                     377280..377282,377289..377294,377301..377306,
                     377337..377339,377346..377351,377361..377363,
                     377370..377375,377382..377384,377523..377525,
                     377535..377537,377544..377546,377556..377558,
                     377568..377570,377619..377621,377628..377633,
                     377640..377645,377652..377654,377898..377900,
                     377916..377921,377928..377933,377973..377975,
                     377982..377987,377994..377999,378006..378011,
                     378159..378164,378168..378173,378183..378185,
                     378192..378197,378204..378206,378258..378263,
                     378267..378275,378282..378284))
                     /gene="lacY"
                     /locus_tag="ECOK1_0335"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(378402..381476)
                     /gene="lacZ"
                     /locus_tag="ECOK1_0336"
                     /db_xref="GeneID:12688904"
     CDS             complement(378402..381476)
                     /gene="lacZ"
                     /locus_tag="ECOK1_0336"
                     /EC_number="3.2.1.23"
                     /note="identified by similarity to SP:P00722; match to
                     protein family HMM PF00703; match to protein family HMM
                     PF02836; match to protein family HMM PF02837; match to
                     protein family HMM PF02929"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="YP_006099577.1"
                     /db_xref="GI:386598071"
                     /db_xref="GeneID:12688904"
                     /translation="MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEAR
                     TDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPDADTVVVPSNWQMHGYDAPIYT
                     NVTYPITVNPPFVPAENPTGCYSLTFNIDESWLQEGQTRIIFDGVNSAFHLWCNGRWV
                     GYGQDSRLPSEFDLSAFLHAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHK
                     PTTQISDFQVTTRFNDDFSRAVLEAEVQMYGELRDELRVTVSLWQGETQVASGTAPFG
                     GEIIDERGGYADRVTLRLNVENPELWSAEIPNLYRAVVELHTADGTLIEAEACDVGFR
                     EVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSH
                     YPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRN
                     HPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVD
                     EDQPFPAVPKWSIKKWLSLPGEMRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGG
                     FVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQ
                     QQFFQFRLSGRTIEVTSEYLFRHSDNEFLHWMVALDGKPLASGEVPLDVGPQGKQLIE
                     LPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPSASHAIPQ
                     LTTSGTDFCIELGNKRWQFNRQSGFLSQMWIGDEKQLLTPLRDQFTRAPLDNDIGVSE
                     ATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKT
                     YRIDGHGEMVINVDVAVASDTPHPARIGLTCQLAQVSERVNWLGLGPQENYPDRLTAA
                     CFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETS
                     HRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK"
     misc_feature    complement(378405..381476)
                     /gene="lacZ"
                     /locus_tag="ECOK1_0336"
                     /note="beta-D-galactosidase; Reviewed; Region: lacZ;
                     PRK09525"
                     /db_xref="CDD:236548"
     misc_feature    complement(380820..381332)
                     /gene="lacZ"
                     /locus_tag="ECOK1_0336"
                     /note="Glycosyl hydrolases family 2, sugar binding domain;
                     Region: Glyco_hydro_2_N; pfam02837"
                     /db_xref="CDD:251564"
     misc_feature    complement(380475..380810)
                     /gene="lacZ"
                     /locus_tag="ECOK1_0336"
                     /note="Glycosyl hydrolases family 2; Region:
                     Glyco_hydro_2; pfam00703"
                     /db_xref="CDD:250069"
     misc_feature    complement(379587..380423)
                     /gene="lacZ"
                     /locus_tag="ECOK1_0336"
                     /note="Glycosyl hydrolases family 2, TIM barrel domain;
                     Region: Glyco_hydro_2_C; pfam02836"
                     /db_xref="CDD:251563"
     misc_feature    complement(378411..379229)
                     /gene="lacZ"
                     /locus_tag="ECOK1_0336"
                     /note="Beta galactosidase small chain; Region:
                     Bgal_small_N; pfam02929"
                     /db_xref="CDD:111779"
     gene            complement(381599..382690)
                     /gene="lacI"
                     /locus_tag="ECOK1_0337"
                     /db_xref="GeneID:12688905"
     CDS             complement(381599..382690)
                     /gene="lacI"
                     /locus_tag="ECOK1_0337"
                     /note="identified by similarity to SP:P03023; match to
                     protein family HMM PF00356; match to protein family HMM
                     PF00532"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose operon repressor"
                     /protein_id="YP_006099578.1"
                     /db_xref="GI:386598072"
                     /db_xref="GeneID:12688905"
                     /translation="MVNVKPVTLYDVAEYAGVSYQTVSRVVNQACHVSAKTREKVEAA
                     MAELNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMV
                     ERSGVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACANVPALFLDVSDQTPIN
                     SIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPIAE
                     REGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGY
                     DDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLP
                     PNTQTASPRALADSLMQLARQVSRLESGQ"
     misc_feature    complement(381662..382684)
                     /gene="lacI"
                     /locus_tag="ECOK1_0337"
                     /note="lac repressor; Reviewed; Region: lacI; PRK09526"
                     /db_xref="CDD:181929"
     misc_feature    complement(382508..382663)
                     /gene="lacI"
                     /locus_tag="ECOK1_0337"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    complement(order(382511..382516,382520..382525,
                     382532..382534,382541..382543,382580..382582,
                     382589..382594,382607..382609,382616..382621,
                     382625..382639,382661..382663))
                     /gene="lacI"
                     /locus_tag="ECOK1_0337"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    complement(382514..382543)
                     /gene="lacI"
                     /locus_tag="ECOK1_0337"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    complement(381698..382492)
                     /gene="lacI"
                     /locus_tag="ECOK1_0337"
                     /note="Ligand-binding domain of DNA transcription
                     repressor LacI specific for lactose, a member of the
                     LacI-GalR family of bacterial transcription regulators;
                     Region: PBP1_LacI; cd01574"
                     /db_xref="CDD:107259"
     misc_feature    complement(order(381860..381862,381944..381946,
                     382091..382093,382103..382105,382199..382201,
                     382235..382237,382307..382309,382445..382447,
                     382454..382459,382475..382477))
                     /gene="lacI"
                     /locus_tag="ECOK1_0337"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107259"
     misc_feature    complement(order(381917..381919,381929..381931,
                     381938..381940,382013..382015,382331..382333,
                     382388..382390,382394..382396,382403..382405,
                     382430..382432,382439..382441,382451..382453,
                     382460..382462,382472..382474))
                     /gene="lacI"
                     /locus_tag="ECOK1_0337"
                     /note="dimerization interface (open form) [polypeptide
                     binding]; other site"
                     /db_xref="CDD:107259"
     misc_feature    complement(order(381917..381919,381938..381940,
                     382328..382330,382430..382432,382448..382450,
                     382466..382468))
                     /gene="lacI"
                     /locus_tag="ECOK1_0337"
                     /note="dimerization interface (closed form) [polypeptide
                     binding]; other site"
                     /db_xref="CDD:107259"
     gene            382883..383422
                     /locus_tag="ECOK1_0338"
                     /db_xref="GeneID:12688906"
     CDS             382883..383422
                     /locus_tag="ECOK1_0338"
                     /note="identified by similarity to GB:CAD09197.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099579.1"
                     /db_xref="GI:386598073"
                     /db_xref="GeneID:12688906"
                     /translation="MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEE
                     NKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMNRITIANGDIGFNFTDGNLIKKI
                     FVDKLTQAQLINGRLAIARLLVDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAE
                     EQDEDDPYADFKVPDDLMW"
     misc_feature    382883..383419
                     /locus_tag="ECOK1_0338"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3122"
                     /db_xref="CDD:225664"
     gene            complement(383648..384481)
                     /gene="fghA"
                     /locus_tag="ECOK1_0339"
                     /db_xref="GeneID:12688907"
     CDS             complement(383648..384481)
                     /gene="fghA"
                     /locus_tag="ECOK1_0339"
                     /EC_number="3.1.2.12"
                     /note="identified by match to protein family HMM PF00756;
                     match to protein family HMM TIGR02821"
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="YP_006099580.1"
                     /db_xref="GI:386598074"
                     /db_xref="GeneID:12688907"
                     /translation="MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAENEKLP
                     VLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGF
                     YLNATQAPWNEHYKMYDYIRNELPNLVMHHFPATARKSISGHSMGGLGALVLALRNPD
                     EYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKDAWLDYDPVSLISQGQRVAEIMVDQG
                     LSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNM
                     R"
     misc_feature    complement(383654..384481)
                     /gene="fghA"
                     /locus_tag="ECOK1_0339"
                     /note="Predicted esterase [General function prediction
                     only]; Region: COG0627"
                     /db_xref="CDD:223700"
     misc_feature    complement(383660..384478)
                     /gene="fghA"
                     /locus_tag="ECOK1_0339"
                     /note="Predicted hydrolase of the alpha/beta superfamily
                     [General function prediction only]; Region: COG2819;
                     cl19187"
                     /db_xref="CDD:267540"
     gene            complement(384574..385683)
                     /gene="adhC"
                     /locus_tag="ECOK1_0340"
                     /db_xref="GeneID:12688908"
     CDS             complement(384574..385683)
                     /gene="adhC"
                     /locus_tag="ECOK1_0340"
                     /EC_number="1.1.1.284"
                     /EC_number="1.1.1.1"
                     /note="identified by similarity to SP:P25437; match to
                     protein family HMM PF00107; match to protein family HMM
                     PF08240; match to protein family HMM TIGR02818"
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase/class
                     III alcohol dehydrogenase"
                     /protein_id="YP_006099581.1"
                     /db_xref="GI:386598075"
                     /db_xref="GeneID:12688908"
                     /translation="MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDA
                     FTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGK
                     TNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEAN
                     HEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
                     TNPKKFELARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALES
                     AHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGD
                     IDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY"
     misc_feature    complement(384580..385683)
                     /gene="adhC"
                     /locus_tag="ECOK1_0340"
                     /note="class III alcohol dehydrogenases; Region:
                     alcohol_DH_class_III; cd08300"
                     /db_xref="CDD:176260"
     misc_feature    complement(384577..385680)
                     /gene="adhC"
                     /locus_tag="ECOK1_0340"
                     /note="S-(hydroxymethyl)glutathione dehydrogenase/class
                     III alcohol dehydrogenase; Region: adh_III_F_hyde;
                     TIGR02818"
                     /db_xref="CDD:131865"
     misc_feature    complement(order(384745..384747,384817..384819,
                     385177..385179,385417..385422,385498..385500,
                     385525..385533,385558..385560,385564..385566))
                     /gene="adhC"
                     /locus_tag="ECOK1_0340"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(385177..385179,385495..385500,
                     385564..385566))
                     /gene="adhC"
                     /locus_tag="ECOK1_0340"
                     /note="catalytic Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(384592..384594,384742..384750,
                     384820..384825,384877..384882,384892..384897,
                     385015..385017,385027..385032,385090..385104,
                     385165..385167,385177..385179,385558..385563))
                     /gene="adhC"
                     /locus_tag="ECOK1_0340"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(385366..385368,385390..385392,
                     385399..385401,385408..385410))
                     /gene="adhC"
                     /locus_tag="ECOK1_0340"
                     /note="structural Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(384745..384762,384769..384777,
                     384784..384807,384814..384816,384841..384852,
                     384871..384876,384907..384909,384922..384924,
                     385363..385365,385369..385371,385375..385380,
                     385384..385386,385393..385398))
                     /gene="adhC"
                     /locus_tag="ECOK1_0340"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:176260"
     gene            complement(385718..385993)
                     /locus_tag="ECOK1_0341"
                     /db_xref="GeneID:12688909"
     CDS             complement(385718..385993)
                     /locus_tag="ECOK1_0341"
                     /note="identified by similarity to SP:P15753; match to
                     protein family HMM PF02583"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099582.1"
                     /db_xref="GI:386598076"
                     /db_xref="GeneID:12688909"
                     /translation="MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAA
                     VRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDDTIELVRAYLK"
     misc_feature    complement(385724..385987)
                     /locus_tag="ECOK1_0341"
                     /note="Transcriptional regulators RcnR and FrmR, and
                     related domains; this domain family was previously known
                     as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153"
                     /db_xref="CDD:197388"
     misc_feature    complement(order(385802..385804,385814..385816,
                     385889..385891,385985..385987))
                     /locus_tag="ECOK1_0341"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:197388"
     misc_feature    complement(order(385733..385762,385766..385771,
                     385799..385801,385808..385816,385820..385828,
                     385832..385837,385844..385849,385856..385861,
                     385865..385870,385874..385882,385886..385894,
                     385898..385909,385916..385921,385925..385930,
                     385937..385939,385946..385951,385958..385963,
                     385970..385972))
                     /locus_tag="ECOK1_0341"
                     /note="putative homotetramer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:197388"
     misc_feature    complement(order(385733..385744,385751..385753,
                     385814..385816,385826..385828,385835..385837,
                     385844..385849,385856..385861,385865..385870,
                     385874..385882,385886..385894,385898..385909,
                     385916..385921,385925..385930,385937..385939,
                     385946..385951,385958..385963,385970..385972))
                     /locus_tag="ECOK1_0341"
                     /note="putative homodimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:197388"
     misc_feature    complement(order(385745..385750,385754..385762,
                     385766..385771,385799..385804,385808..385813,
                     385820..385825,385832..385834))
                     /locus_tag="ECOK1_0341"
                     /note="putative homodimer-homodimer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:197388"
     misc_feature    complement(order(385751..385753,385814..385816))
                     /locus_tag="ECOK1_0341"
                     /note="putative allosteric switch controlling residues;
                     other site"
                     /db_xref="CDD:197388"
     gene            complement(386182..386955)
                     /locus_tag="ECOK1_0342"
                     /db_xref="GeneID:12688910"
     CDS             complement(386182..386955)
                     /locus_tag="ECOK1_0342"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099583.1"
                     /db_xref="GI:386598077"
                     /db_xref="GeneID:12688910"
                     /translation="MIKRTLLAAAIFSALPVYAGLTSITAGYDFTDYSGDHGNRNLAY
                     AELVAKVENATLLFNLSQGRRDYETEHFNATRGQGAVWYKWNNWLTTRTGIAFADNTP
                     VFARQDFRQDINLALLPKTLFTTGYRYTKYYDDVEVDAWQGGISLYTGPVITSYRYTH
                     YDSSDAGGSYSNMISVRLNDPRGTGYTQLWLSRGTGAYTYDWTPETRYGSMKSISLQR
                     IQPLTEQLNLGLTAGKVWYDTPTDDYNGLQLAAHLTWKF"
     gene            complement(386957..387481)
                     /locus_tag="ECOK1_0343"
                     /db_xref="GeneID:12688911"
     CDS             complement(386957..387481)
                     /locus_tag="ECOK1_0343"
                     /note="identified by match to protein family HMM PF00132"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyltransferase"
                     /protein_id="YP_006099584.1"
                     /db_xref="GI:386598078"
                     /db_xref="GeneID:12688911"
                     /translation="MIIDESAGEVVIGANTRICHGAVIQGPVVIGANCLIGNYAFIRP
                     GTIISNGVRIGFATEIKNAVIEAEATIGPQCFIADSVVANQAYLGAQVRTSNHRLDEQ
                     PVSVRTPDGIIATGCDKLGCYIGQRSRLGVQVIILPGRIISPNTQLGPRVIVERNLPT
                     GTYSLRQELIRTGD"
     misc_feature    complement(387017..387460)
                     /locus_tag="ECOK1_0343"
                     /note="Left-handed parallel beta-Helix (LbetaH or LbH)
                     domain: The alignment contains 5 turns, each containing
                     three imperfect tandem repeats of a hexapeptide repeat
                     motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing
                     hexapeptide repeats are often enzymes...; Region: LbetaH;
                     cl00160"
                     /db_xref="CDD:260227"
     misc_feature    complement(order(387017..387019,387023..387025,
                     387029..387031,387041..387043,387071..387073,
                     387077..387082,387095..387097,387197..387199,
                     387203..387205,387221..387223,387248..387250,
                     387254..387256,387266..387268,387272..387274))
                     /locus_tag="ECOK1_0343"
                     /note="putative trimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:100038"
     misc_feature    complement(order(387017..387019,387035..387037,
                     387071..387073,387086..387091,387095..387097))
                     /locus_tag="ECOK1_0343"
                     /note="putative CoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100038"
     gene            complement(387516..388712)
                     /locus_tag="ECOK1_0344"
                     /db_xref="GeneID:12688912"
     CDS             complement(387516..388712)
                     /locus_tag="ECOK1_0344"
                     /EC_number="2.4.1.-"
                     /note="identified by match to protein family HMM PF00535"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_006099585.1"
                     /db_xref="GI:386598079"
                     /db_xref="GeneID:12688912"
                     /translation="MKTWIFICMAVAILLWFLSTLRRKPSQKKGCIDAIIPAYNEGPC
                     LAQSLDNLLRNPYFCRVICVNDGSMDNTEAVMAEVKRKWGDRFVAVTQKNTGKGGALM
                     NGLNYATCDQVFLSDADTYVPPDQDGMGYMLAEIERGADAVGGIPSTALKGAGLLPHI
                     RATVKLPMIVMKRTLQQLLGGAPFIISGACGMFRTDVLRKFGFSDRTKVEDLDLTWTL
                     VANGYRIRQANRCIVYPQECNSPREEWRRWRRWIVGYAVCMRLHKRLLFSRFGIFSIF
                     PMLLVVLYGVGIYLTTWFNEFITTGPHGVVLAMFPLIWVGVVCVIGAFSAWFHRCWLL
                     VPLAPLSVVYVLLAYAIWIIYGLIAFFTGREPQRDKPTRYSALVEASTAYSHPSVTGT
                     EKLSEA"
     misc_feature    complement(387795..388619)
                     /locus_tag="ECOK1_0344"
                     /note="Glycosyltransferases involved in cell wall
                     biogenesis [Cell envelope biogenesis, outer membrane];
                     Region: WcaA; COG0463"
                     /db_xref="CDD:223539"
     misc_feature    complement(388080..388610)
                     /locus_tag="ECOK1_0344"
                     /note="CESA_like is  the cellulose synthase superfamily;
                     Region: CESA_like; cd06423"
                     /db_xref="CDD:133045"
     misc_feature    complement(388356..388364)
                     /locus_tag="ECOK1_0344"
                     /note="DXD motif; other site"
                     /db_xref="CDD:133045"
     gene            complement(388722..389393)
                     /locus_tag="ECOK1_0345"
                     /db_xref="GeneID:12688913"
     CDS             complement(388722..389393)
                     /locus_tag="ECOK1_0345"
                     /note="identified by match to protein family HMM PF02585"
                     /codon_start=1
                     /transl_table=11
                     /product="putative GlcNAc-PI de-N-acetylase"
                     /protein_id="YP_006099586.1"
                     /db_xref="GI:386598080"
                     /db_xref="GeneID:12688913"
                     /translation="MDKVLDSAILSSANKRKGILAIGAHPDDIELGCGASLARLAQKG
                     IYIATVVMTTGNSGVDGIIDRHEESRNALKILGCHQTIHLNFADTRAHLQLNDMISAL
                     ENIIKNQIPSDVEIIRVYTMHDADRHQDHLAVYQASMVACRAIPQILGYETPSTWLSF
                     MPQVFESVKEEYFSLKLTALKKHKSQSQRDYMRPERLRAVAQFRGQQVNSDLGEGFVI
                     HKMIL"
     misc_feature    complement(388779..389369)
                     /locus_tag="ECOK1_0345"
                     /note="Uncharacterized proteins, LmbE homologs [Function
                     unknown]; Region: COG2120"
                     /db_xref="CDD:225031"
     gene            complement(389853..390047)
                     /locus_tag="ECOK1_0346"
                     /db_xref="GeneID:12688914"
     CDS             complement(389853..390047)
                     /locus_tag="ECOK1_0346"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099587.1"
                     /db_xref="GI:386598081"
                     /db_xref="GeneID:12688914"
                     /translation="MNASAARNVLRDEITMIVCSPVLLWEQYSGIKTFIKRISRYRTD
                     DFILSKKAAKERLNMQLRPL"
     gene            390001..390963
                     /gene="tauA"
                     /locus_tag="ECOK1_0347"
                     /db_xref="GeneID:12688915"
     CDS             390001..390963
                     /gene="tauA"
                     /locus_tag="ECOK1_0347"
                     /note="identified by match to protein family HMM PF04069;
                     match to protein family HMM TIGR01729"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter, periplasmic
                     taurine-binding protein"
                     /protein_id="YP_006099588.1"
                     /db_xref="GI:386598082"
                     /db_xref="GeneID:12688915"
                     /translation="MVISSRNTFLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNT
                     FAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVATSQQVPIEVFLLASKL
                     GNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
                     IIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHP
                     EVVKAFAKSAIDAQQPYIANPDAWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQ
                     QQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ"
     misc_feature    390073..390912
                     /gene="tauA"
                     /locus_tag="ECOK1_0347"
                     /note="ABC transporter, substrate-binding protein,
                     aliphatic sulfonates family; Region: SsuA_fam; TIGR01728"
                     /db_xref="CDD:130789"
     misc_feature    390127..390729
                     /gene="tauA"
                     /locus_tag="ECOK1_0347"
                     /note="Bacterial periplasmic transport systems use
                     membrane-bound complexes and substrate-bound,
                     membrane-associated, periplasmic binding proteins (PBPs)
                     to transport a wide variety of  substrates, such as, amino
                     acids, peptides, sugars, vitamins and inorganic...;
                     Region: PBPb; cd00134"
                     /db_xref="CDD:238078"
     misc_feature    order(390178..390180,390256..390258,390394..390396,
                     390526..390528)
                     /gene="tauA"
                     /locus_tag="ECOK1_0347"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238078"
     misc_feature    order(390475..390477,390487..390489,390505..390507)
                     /gene="tauA"
                     /locus_tag="ECOK1_0347"
                     /note="membrane-bound complex binding site; other site"
                     /db_xref="CDD:238078"
     misc_feature    390601..390618
                     /gene="tauA"
                     /locus_tag="ECOK1_0347"
                     /note="hinge residues; other site"
                     /db_xref="CDD:238078"
     gene            390976..391743
                     /gene="tauB"
                     /locus_tag="ECOK1_0348"
                     /db_xref="GeneID:12688916"
     CDS             390976..391743
                     /gene="tauB"
                     /locus_tag="ECOK1_0348"
                     /EC_number="3.6.3.36"
                     /note="identified by similarity to SP:Q47538; match to
                     protein family HMM PF00005"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter ATP-binding protein"
                     /protein_id="YP_006099589.1"
                     /db_xref="GI:386598083"
                     /db_xref="GeneID:12688916"
                     /translation="MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLL
                     NLIAGFVPYQHGSIQLAGKGIQGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGVEK
                     MQRLEIAHQMVKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD
                     AFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPGPGRVLERLPLNFA
                     RRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS"
     misc_feature    390976..391740
                     /gene="tauB"
                     /locus_tag="ECOK1_0348"
                     /note="taurine transporter ATP-binding subunit;
                     Provisional; Region: tauB; PRK11248"
                     /db_xref="CDD:183056"
     misc_feature    390979..391626
                     /gene="tauB"
                     /locus_tag="ECOK1_0348"
                     /note="ATP-binding cassette domain of the nitrate and
                     sulfonate transporters; Region:
                     ABC_NrtD_SsuB_transporters; cd03293"
                     /db_xref="CDD:213260"
     misc_feature    391075..391098
                     /gene="tauB"
                     /locus_tag="ECOK1_0348"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213260"
     misc_feature    order(391084..391089,391093..391101,391204..391206,
                     391432..391437,391534..391536)
                     /gene="tauB"
                     /locus_tag="ECOK1_0348"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213260"
     misc_feature    391195..391206
                     /gene="tauB"
                     /locus_tag="ECOK1_0348"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213260"
     misc_feature    391360..391389
                     /gene="tauB"
                     /locus_tag="ECOK1_0348"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213260"
     misc_feature    391420..391437
                     /gene="tauB"
                     /locus_tag="ECOK1_0348"
                     /note="Walker B; other site"
                     /db_xref="CDD:213260"
     misc_feature    391444..391455
                     /gene="tauB"
                     /locus_tag="ECOK1_0348"
                     /note="D-loop; other site"
                     /db_xref="CDD:213260"
     misc_feature    391522..391542
                     /gene="tauB"
                     /locus_tag="ECOK1_0348"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213260"
     gene            391740..392567
                     /gene="tauC"
                     /locus_tag="ECOK1_0349"
                     /db_xref="GeneID:12688917"
     CDS             391740..392567
                     /gene="tauC"
                     /locus_tag="ECOK1_0349"
                     /note="identified by similarity to Q47539; match to
                     protein family HMM PF00528"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine uptake ABC transporter, permease
                     protein"
                     /protein_id="YP_006099590.1"
                     /db_xref="GI:386598084"
                     /db_xref="GeneID:12688917"
                     /translation="MSVLINEKLHSHRLKWRWPLSRQVTLSIGTLAVLLTVWWAVAAL
                     QLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHLAASLTRIVLALLAAVLIGIPVG
                     IAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
                     ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAE
                     LIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ"
     misc_feature    391782..392564
                     /gene="tauC"
                     /locus_tag="ECOK1_0349"
                     /note="ABC-type nitrate/sulfonate/bicarbonate transport
                     system, permease component [Inorganic ion transport and
                     metabolism]; Region: TauC; COG0600"
                     /db_xref="CDD:223673"
     misc_feature    391977..392405
                     /gene="tauC"
                     /locus_tag="ECOK1_0349"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(392025..392030,392037..392042,392055..392057,
                     392082..392093,392097..392126,392133..392138,
                     392142..392144,392190..392195,392199..392201,
                     392205..392207,392214..392219,392223..392225,
                     392235..392240,392247..392249,392298..392300,
                     392340..392345,392352..392354,392373..392384,
                     392391..392396)
                     /gene="tauC"
                     /locus_tag="ECOK1_0349"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(392100..392144,392373..392390)
                     /gene="tauC"
                     /locus_tag="ECOK1_0349"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(392142..392144,392175..392177,392391..392393)
                     /gene="tauC"
                     /locus_tag="ECOK1_0349"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(392250..392288,392304..392309,392319..392321)
                     /gene="tauC"
                     /locus_tag="ECOK1_0349"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            392564..393415
                     /gene="tauD"
                     /locus_tag="ECOK1_0350"
                     /db_xref="GeneID:12688918"
     CDS             392564..393415
                     /gene="tauD"
                     /locus_tag="ECOK1_0350"
                     /EC_number="1.14.11.17"
                     /note="identified by similarity to SP:P37610; match to
                     protein family HMM PF02668"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine dioxygenase"
                     /protein_id="YP_006099591.1"
                     /db_xref="GI:386598085"
                     /db_xref="GeneID:12688918"
                     /translation="MSERLSITPLGPYIGAQITGADLTRPLSDNQFEQLYHAVLRHHV
                     VFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDV
                     TFIQTPPAGAILAAKELPSTGGDTLWASGIAAYEALSVPFRQLLSGLRAEHDFRKSFP
                     EYKYRKTEAEHQRWREAVAKNPPLLHPVVRTHPVTGKQALFVNEGFTTRIVDVSEKES
                     EALLGFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGD
                     IPFYRAG"
     misc_feature    392564..393412
                     /gene="tauD"
                     /locus_tag="ECOK1_0350"
                     /note="Probable taurine catabolism dioxygenase [Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: TauD; COG2175"
                     /db_xref="CDD:225086"
     misc_feature    392570..393400
                     /gene="tauD"
                     /locus_tag="ECOK1_0350"
                     /note="taurine dioxygenase; Reviewed; Region: tauD;
                     PRK09553"
                     /db_xref="CDD:181947"
     misc_feature    order(392858..392860,392864..392866,392939..392941,
                     393326..393328)
                     /gene="tauD"
                     /locus_tag="ECOK1_0350"
                     /note="active site"
                     /db_xref="CDD:238154"
     misc_feature    order(392858..392860,392864..392866,393326..393328)
                     /gene="tauD"
                     /locus_tag="ECOK1_0350"
                     /note="iron coordination sites [ion binding]; other site"
                     /db_xref="CDD:238154"
     misc_feature    order(392867..392869,392873..392875,392888..392890,
                     393029..393031)
                     /gene="tauD"
                     /locus_tag="ECOK1_0350"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238154"
     gene            complement(393455..394429)
                     /gene="hemB"
                     /locus_tag="ECOK1_0351"
                     /db_xref="GeneID:12688919"
     CDS             complement(393455..394429)
                     /gene="hemB"
                     /locus_tag="ECOK1_0351"
                     /EC_number="4.2.1.24"
                     /note="identified by similarity to SP:P0ACB3; match to
                     protein family HMM PF00490"
                     /codon_start=1
                     /transl_table=11
                     /product="delta-aminolevulinic acid dehydratase"
                     /protein_id="YP_006099592.1"
                     /db_xref="GI:386598086"
                     /db_xref="GeneID:12688919"
                     /translation="MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDY
                     KAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARM
                     SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGAD
                     FIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKS
                     YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEY
                     AMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR"
     misc_feature    complement(393470..394405)
                     /gene="hemB"
                     /locus_tag="ECOK1_0351"
                     /note="Porphobilinogen synthase (PBGS), which is also
                     called delta-aminolevulinic acid dehydratase (ALAD),
                     catalyzes the condensation of two 5-aminolevulinic acid
                     (ALA) molecules to form the pyrrole porphobilinogen (PBG),
                     which is the second step in the...; Region: ALAD_PBGS;
                     cd00384"
                     /db_xref="CDD:238226"
     misc_feature    complement(order(393521..393523,393530..393532,
                     393542..393544,393596..393598,393668..393682,
                     393734..393739,393746..393748,393764..393766,
                     393773..393775,393830..393838,393923..393928,
                     394007..394012,394277..394279,394286..394288,
                     394358..394360,394391..394396,394403..394405))
                     /gene="hemB"
                     /locus_tag="ECOK1_0351"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238226"
     misc_feature    complement(order(393494..393496,393611..393613,
                     393620..393622,393689..393691,393770..393772,
                     393782..393784,393800..393802,393815..393820,
                     393827..393829,393845..393847,393935..393937,
                     394040..394042,394064..394066,394070..394072,
                     394076..394078))
                     /gene="hemB"
                     /locus_tag="ECOK1_0351"
                     /note="active site"
                     /db_xref="CDD:238226"
     misc_feature    complement(order(393689..393691,393845..393847))
                     /gene="hemB"
                     /locus_tag="ECOK1_0351"
                     /note="Schiff base residues; other site"
                     /db_xref="CDD:238226"
     gene            394955..397942
                     /locus_tag="ECOK1_0352"
                     /db_xref="GeneID:12688920"
     CDS             394955..397942
                     /locus_tag="ECOK1_0352"
                     /note="identified by match to protein family HMM PF03212;
                     match to protein family HMM PF03797; match to protein
                     family HMM TIGR01414"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane autotransporter"
                     /protein_id="YP_006099593.1"
                     /db_xref="GI:386598087"
                     /db_xref="GeneID:12688920"
                     /translation="MHSWKKKLVVSQLALACTLAITSQANAANYDTWGYHDNTTTDLV
                     WPYDTDNDGIADAGGMDPMGSDGNYVTYNGFVYYNNANGDFDTVFKGDTVNGTISTYY
                     LNHDYASGSVNQVDISNSVIHGAITSELPFGYYSITPAEVNAKGEVVTPQTYNGYNFY
                     NGITTDLDYNWYDGDVFTLNVSNSTIDDDYEALYFTDTYLDGDKSKSTNETFYTALGV
                     AVNLDVESNINITNNSRVAGIALSEGNTSNTTYTSEYHQWDNNINVSNSTVTSGSQTP
                     LEESNGFFGKSAEPSDYAGNGGENDVALSFSDNAGSNYSMKNNVNFDHSTLLGDVEFT
                     SHWNNDGVFFYSTGHDSNGDGVLDTNGGWVDDAQNVDELNITLNNGSKWVGSANMSAE
                     VIAPADMYDVAPNSLTPGATIEANDWGRIIDNKVFQSGVFNVALNNGSEWNTVNSSVI
                     DTLAVNNGSQVNVTDSSLVSDTIGLTNGSSLNIGEDGLVATDHLTVDSYSTVNLTEST
                     GWNNYSNLYANIITVTNGGVLDVNVDQFDTEAFRTDKLELTSGNIADHNGNVVSGVFD
                     INSSDYVLNADLVNDRTWDTAQANYGYGVVAMNSDGHLTINGNGDVDNGTELDNSSVD
                     NVVAATGNYKVRIDNATGAGAIADYKDKEIIYVNDVNSNATFSAANKADLGAYTYQAE
                     QRGNTVVLQQMELTDYANMALSIPSANTNIWNLEQDTVGTRLTNSRHGLADNGGAWVS
                     YFGGNFNGDNGTINYDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMNDRSGQVD
                     QDSQTAYIYSSAHFANNVFVDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFGLKA
                     GYDFKLGDAGYVTPYGSVSGLFQSGDDYQLSNDMKVDGQSYDSMRYELGVDAGYTFTY
                     SEDQALTPYFKLAYVYDDSNNDNDVNGDSIDNGTEGSAVRVGLGTQFSFTKNFSAYTD
                     ANYLGGGDVDQDWSANVGVKYTW"
     misc_feature    396563..397015
                     /locus_tag="ECOK1_0352"
                     /note="Pertactin-like passenger domains (virulence
                     factors) of autotransporter proteins of the type V
                     secretion system. Autotransporters are proteins used by
                     Gram-negative bacteria to transport proteins across their
                     outer membranes. The C-terminal (beta) domain...; Region:
                     PL_Passenger_AT; cl00185"
                     /db_xref="CDD:260243"
     misc_feature    396722..397939
                     /locus_tag="ECOK1_0352"
                     /note="outer membrane autotransporter barrel domain;
                     Region: autotrans_barl; TIGR01414"
                     /db_xref="CDD:233402"
     misc_feature    397148..397894
                     /locus_tag="ECOK1_0352"
                     /note="Autotransporter beta-domain; Region:
                     Autotransporter; pfam03797"
                     /db_xref="CDD:252169"
     gene            398028..398651
                     /locus_tag="ECOK1_0353"
                     /db_xref="GeneID:12688921"
     CDS             398028..398651
                     /locus_tag="ECOK1_0353"
                     /note="identified by similarity to GB:AAN78957.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099594.1"
                     /db_xref="GI:386598088"
                     /db_xref="GeneID:12688921"
                     /translation="MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSNVNSEDT
                     FVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQT
                     ITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRI
                     GVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY"
     misc_feature    398028..398648
                     /locus_tag="ECOK1_0353"
                     /note="putative DNA-binding transcriptional regulator;
                     Provisional; Region: PRK11832"
                     /db_xref="CDD:183332"
     gene            complement(398652..399809)
                     /gene="ampH"
                     /locus_tag="ECOK1_0354"
                     /db_xref="GeneID:12688922"
     CDS             complement(398652..399809)
                     /gene="ampH"
                     /locus_tag="ECOK1_0354"
                     /note="identified by similarity to SP:P0AD70; match to
                     protein family HMM PF00144"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein AmpH"
                     /protein_id="YP_006099595.1"
                     /db_xref="GI:386598089"
                     /db_xref="GeneID:12688922"
                     /translation="MKRSLLFSAVLYAASLTSVHTAQPITEPEFASDIVDRYADHIFY
                     GSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLDSVIRIASLTKLMTSEMLVKLLD
                     QGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
                     REQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMK
                     DTTYTPSPDQCRRLMVAERGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQR
                     SNQADRMQTLIYQRAQFTKVIGMDVPGKADALGLGWVYMAPKEGRPGIIQKTGGGGGF
                     ITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS"
     misc_feature    complement(398676..399809)
                     /gene="ampH"
                     /locus_tag="ECOK1_0354"
                     /note="beta-lactam binding protein AmpH; Provisional;
                     Region: PRK10662"
                     /db_xref="CDD:236732"
     gene            400161..401381
                     /gene="smbA"
                     /locus_tag="ECOK1_0355"
                     /db_xref="GeneID:12688923"
     CDS             400161..401381
                     /gene="smbA"
                     /locus_tag="ECOK1_0355"
                     /note="identified by similarity to SP:P0AFY6; match to
                     protein family HMM PF05992; match to protein family HMM
                     PF06472"
                     /codon_start=1
                     /transl_table=11
                     /product="protein SbmA"
                     /protein_id="YP_006099596.1"
                     /db_xref="GI:386598090"
                     /db_xref="GeneID:12688923"
                     /translation="MFKSFFPKPGTFFLSAFVWALIAVIFWQAGGGDWVARITGASGQ
                     IPISAARFWSLDFLIFYAYYIVCVGLFALFWFIYSPHRWQYWSILGTALIIFVTWFLV
                     EVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVS
                     HYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
                     FLPVLVTLSAHVPELPIVGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVE
                     AAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFG
                     LFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHE
                     LDGDKIQEVTHTLS"
     misc_feature    400161..401378
                     /gene="smbA"
                     /locus_tag="ECOK1_0355"
                     /note="microcin B17 transporter; Reviewed; Region:
                     PRK11098"
                     /db_xref="CDD:182960"
     gene            401394..402488
                     /locus_tag="ECOK1_0356"
                     /db_xref="GeneID:12688924"
     CDS             401394..402488
                     /locus_tag="ECOK1_0356"
                     /note="identified by match to protein family HMM PF07759"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipoprotein"
                     /protein_id="YP_006099597.1"
                     /db_xref="GI:386598091"
                     /db_xref="GeneID:12688924"
                     /translation="MSRVNPLSSLSLLAVLILAGCSSQAPQPLKKGEKAIDVASVVRQ
                     KMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIA
                     WQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSAIFDDLISMVPM
                     GQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLL
                     NYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYDSKEPGKTE
                     LATRKLAGKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAEAKTGKSLPREMLPGI
                     QLESPKITRNLTTAWFAKRVDERRARCMKQ"
     misc_feature    401535..402482
                     /locus_tag="ECOK1_0356"
                     /note="Protein of unknown function (DUF1615); Region:
                     DUF1615; pfam07759"
                     /db_xref="CDD:254411"
     gene            complement(402547..402855)
                     /locus_tag="ECOK1_0357"
                     /db_xref="GeneID:12688925"
     CDS             complement(402547..402855)
                     /locus_tag="ECOK1_0357"
                     /note="identified by similarity to SP:P0AAP7"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099598.1"
                     /db_xref="GI:386598092"
                     /db_xref="GeneID:12688925"
                     /translation="MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNL
                     LVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIPFLVGCLIFAVVALWLHWRHRRQ
                     "
     misc_feature    complement(402553..402855)
                     /locus_tag="ECOK1_0357"
                     /note="Protein of unknown function (DUF2755); Region:
                     DUF2755; pfam10954"
                     /db_xref="CDD:151401"
     gene            402983..403327
                     /locus_tag="ECOK1_0358"
                     /db_xref="GeneID:12688926"
     CDS             402983..403327
                     /locus_tag="ECOK1_0358"
                     /note="identified by similarity to GB:AAZ87131.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099599.1"
                     /db_xref="GI:386598093"
                     /db_xref="GeneID:12688926"
                     /translation="MNLRCESQNSNLKLNLLTIAKVLSTPQTVVTEYARMLFFVNGAA
                     MNLPVKIRRDWHYYAFAIGLIFILNGVVGLLGFEAKGWQTYAVGLVTWVISFWLAGLI
                     IRRRDEETENAQ"
     misc_feature    403115..403324
                     /locus_tag="ECOK1_0358"
                     /note="Protein of unknown function (DUF2754); Region:
                     DUF2754; pfam10953"
                     /db_xref="CDD:256211"
     gene            complement(403351..404445)
                     /gene="ddlA"
                     /locus_tag="ECOK1_0359"
                     /db_xref="GeneID:12688927"
     CDS             complement(403351..404445)
                     /gene="ddlA"
                     /locus_tag="ECOK1_0359"
                     /EC_number="6.3.2.4"
                     /note="identified by similarity to SP:P0A6J8; match to
                     protein family HMM PF01820; match to protein family HMM
                     PF02222; match to protein family HMM PF07478; match to
                     protein family HMM TIGR01205"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="YP_006099600.1"
                     /db_xref="GI:386598094"
                     /db_xref="GeneID:12688927"
                     /translation="MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGID
                     KQGQWHVSDASNYLLNADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVI
                     FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFIT
                     LTRANRHNISFAEVESKLGLPLFVKPANQGSSVGVSKVTSEEQYTIAVDLAFEFDHKV
                     IVEQGIKGREIECAVLGNDNPQASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAP
                     EINDKIRAIAVQAYQTLGCAGMARVDVFLTPENEVVINEINTLPGFTNISMYPKLWQA
                     SGLGYTDLITRLIELALERHAADNALKTTM"
     misc_feature    complement(403390..404445)
                     /gene="ddlA"
                     /locus_tag="ECOK1_0359"
                     /note="D-alanyl-alanine synthetase A; Reviewed; Region:
                     ddl; PRK01966"
                     /db_xref="CDD:234993"
     misc_feature    complement(404056..404436)
                     /gene="ddlA"
                     /locus_tag="ECOK1_0359"
                     /note="D-ala D-ala ligase N-terminus; Region:
                     Dala_Dala_lig_N; pfam01820"
                     /db_xref="CDD:250892"
     misc_feature    complement(403402..404007)
                     /gene="ddlA"
                     /locus_tag="ECOK1_0359"
                     /note="D-ala D-ala ligase C-terminus; Region:
                     Dala_Dala_lig_C; pfam07478"
                     /db_xref="CDD:254223"
     gene            404523..404645
                     /locus_tag="ECOK1_0360"
                     /db_xref="GeneID:12688928"
     CDS             404523..404645
                     /locus_tag="ECOK1_0360"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099601.1"
                     /db_xref="GI:386598095"
                     /db_xref="GeneID:12688928"
                     /translation="MLQSSADKASNVLVKKVRYLKDVCKITKMMNGKLIYSWLK"
     gene            404908..405168
                     /locus_tag="ECOK1_0361"
                     /db_xref="GeneID:12688929"
     CDS             404908..405168
                     /locus_tag="ECOK1_0361"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099602.1"
                     /db_xref="GI:386598096"
                     /db_xref="GeneID:12688929"
                     /translation="MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQND
                     QQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLRHPRQ"
     misc_feature    404908..405165
                     /locus_tag="ECOK1_0361"
                     /note="anti-RssB factor; Provisional; Region: PRK10244"
                     /db_xref="CDD:236666"
     gene            405269..406684
                     /gene="phoA"
                     /locus_tag="ECOK1_0362"
                     /db_xref="GeneID:12688930"
     CDS             405269..406684
                     /gene="phoA"
                     /locus_tag="ECOK1_0362"
                     /EC_number="3.1.3.1"
                     /note="identified by similarity to SP:P00634; match to
                     protein family HMM PF00245"
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="YP_006099603.1"
                     /db_xref="GI:386598097"
                     /db_xref="GeneID:12688930"
                     /translation="MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGA
                     RRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPL
                     TGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKA
                     AGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLL
                     NARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDTASLNSVTEANQQKP
                     LLGLFADGNMPVRWQGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSK
                     NEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKDGNTLVIVTADH
                     AHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAAN
                     VVGLTDQTDLFYTMKAALGLK"
     misc_feature    405284..406681
                     /gene="phoA"
                     /locus_tag="ECOK1_0362"
                     /note="Alkaline phosphatase [Inorganic ion transport and
                     metabolism]; Region: PhoA; COG1785"
                     /db_xref="CDD:224699"
     misc_feature    405443..406678
                     /gene="phoA"
                     /locus_tag="ECOK1_0362"
                     /note="Alkaline phosphatase homologues; alkaline
                     phosphatases are non-specific phosphomonoesterases that
                     catalyze the hydrolysis reaction via a phosphoseryl
                     intermediate to produce inorganic phosphate and the
                     corresponding alcohol, optimally at high pH; Region:
                     alkPPc; cd00016"
                     /db_xref="CDD:237983"
     misc_feature    order(405443..405451,405497..405502,405509..405511,
                     405518..405523,405560..405562,405569..405571,
                     405575..405583,405587..405589,405593..405595,
                     405599..405601,405629..405631,405668..405676,
                     405704..405706,405719..405721,406451..406453,
                     406457..406468,406523..406528,406541..406546,
                     406565..406567,406571..406582,406586..406588,
                     406625..406636,406640..406645,406652..406654)
                     /gene="phoA"
                     /locus_tag="ECOK1_0362"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:237983"
     misc_feature    order(405485..405487,405635..405640,405791..405793,
                     405797..405799,405830..405832,406298..406300,
                     406313..406318,406325..406327,406439..406444,
                     406568..406570)
                     /gene="phoA"
                     /locus_tag="ECOK1_0362"
                     /note="active site"
                     /db_xref="CDD:237983"
     gene            406803..407123
                     /gene="psiF"
                     /locus_tag="ECOK1_0363"
                     /db_xref="GeneID:12688931"
     CDS             406803..407123
                     /gene="psiF"
                     /locus_tag="ECOK1_0363"
                     /note="identified by match to protein family HMM PF07769"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PsiF"
                     /protein_id="YP_006099604.1"
                     /db_xref="GI:386598098"
                     /db_xref="GeneID:12688931"
                     /translation="MKITLLVTLLFGLVFLTTVGAAERTLTPQQQRMTSCNQQATAQA
                     LKGDARKTYMSDCLKNSKSAPGEKSLTPQQQKMRECNNQATQQSLKGDDRNKFMSACL
                     KKAA"
     misc_feature    406803..407120
                     /gene="psiF"
                     /locus_tag="ECOK1_0363"
                     /note="hypothetical protein; Provisional; Region:
                     PRK11505"
                     /db_xref="CDD:183165"
     misc_feature    406878..406979
                     /gene="psiF"
                     /locus_tag="ECOK1_0363"
                     /note="psiF repeat; Region: PsiF_repeat; pfam07769"
                     /db_xref="CDD:254417"
     misc_feature    407007..407111
                     /gene="psiF"
                     /locus_tag="ECOK1_0363"
                     /note="psiF repeat; Region: PsiF_repeat; pfam07769"
                     /db_xref="CDD:254417"
     gene            407225..408340
                     /locus_tag="ECOK1_0364"
                     /db_xref="GeneID:12688932"
     CDS             407225..408340
                     /locus_tag="ECOK1_0364"
                     /note="identified by match to protein family HMM PF00990;
                     match to protein family HMM PF05230; match to protein
                     family HMM TIGR00254"
                     /codon_start=1
                     /transl_table=11
                     /product="MASE2 domain/diguanylate cyclase"
                     /protein_id="YP_006099605.1"
                     /db_xref="GI:386598099"
                     /db_xref="GeneID:12688932"
                     /translation="MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLP
                     RAVGLAGMFLPIASTLVSHPSPGWWWLLLVGWAFVWPHLAWQIASRAVDPLSREIYNL
                     KTDAVLAGMWVGVMGVNALPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLEL
                     TGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGV
                     YNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQ
                     ITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVTLRISVG
                     VAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA"
     misc_feature    407240..408337
                     /locus_tag="ECOK1_0364"
                     /note="diguanylate cyclase AdrA; Provisional; Region:
                     adrA; PRK10245"
                     /db_xref="CDD:182329"
     misc_feature    407339..407611
                     /locus_tag="ECOK1_0364"
                     /note="MASE2 domain; Region: MASE2; pfam05230"
                     /db_xref="CDD:147434"
     misc_feature    407855..408322
                     /locus_tag="ECOK1_0364"
                     /note="Diguanylate-cyclase (DGC) or GGDEF domain; Region:
                     GGDEF; cd01949"
                     /db_xref="CDD:143635"
     misc_feature    order(407966..407968,408095..408097)
                     /locus_tag="ECOK1_0364"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143635"
     misc_feature    order(407981..407983,407990..407995,408005..408007,
                     408017..408019,408083..408085,408089..408100)
                     /locus_tag="ECOK1_0364"
                     /note="active site"
                     /db_xref="CDD:143635"
     misc_feature    order(408071..408073,408155..408157)
                     /locus_tag="ECOK1_0364"
                     /note="I-site; other site"
                     /db_xref="CDD:143635"
     gene            complement(408357..409166)
                     /gene="proC"
                     /locus_tag="ECOK1_0365"
                     /db_xref="GeneID:12688933"
     CDS             complement(408357..409166)
                     /gene="proC"
                     /locus_tag="ECOK1_0365"
                     /EC_number="1.5.1.2"
                     /note="identified by match to protein family HMM PF03446;
                     match to protein family HMM PF03807; match to protein
                     family HMM TIGR00112"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="YP_006099606.1"
                     /db_xref="GI:386598100"
                     /db_xref="GeneID:12688933"
                     /translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVTV
                     LHDQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGITL
                     DQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
                     AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLET
                     GEHPGTLKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS"
     misc_feature    complement(408360..409166)
                     /gene="proC"
                     /locus_tag="ECOK1_0365"
                     /note="pyrroline-5-carboxylate reductase; Reviewed;
                     Region: PRK11880"
                     /db_xref="CDD:237008"
     misc_feature    complement(408870..409157)
                     /gene="proC"
                     /locus_tag="ECOK1_0365"
                     /note="NADP oxidoreductase coenzyme F420-dependent;
                     Region: F420_oxidored; pfam03807"
                     /db_xref="CDD:252177"
     misc_feature    complement(408369..408689)
                     /gene="proC"
                     /locus_tag="ECOK1_0365"
                     /note="Pyrroline-5-carboxylate reductase dimerization;
                     Region: P5CR_dimer; pfam14748"
                     /db_xref="CDD:258885"
     gene            409286..409744
                     /locus_tag="ECOK1_0366"
                     /db_xref="GeneID:12688934"
     CDS             409286..409744
                     /locus_tag="ECOK1_0366"
                     /note="identified by similarity to SP:Q3Z523; match to
                     protein family HMM PF02639"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099607.1"
                     /db_xref="GI:386598101"
                     /db_xref="GeneID:12688934"
                     /translation="MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRF
                     IRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATI
                     RERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG"
     misc_feature    409286..409738
                     /locus_tag="ECOK1_0366"
                     /note="hypothetical protein; Validated; Region: PRK00124"
                     /db_xref="CDD:178882"
     gene            409927..410451
                     /gene="aroL"
                     /locus_tag="ECOK1_0367"
                     /db_xref="GeneID:12688935"
     CDS             409927..410451
                     /gene="aroL"
                     /locus_tag="ECOK1_0367"
                     /EC_number="2.7.1.71"
                     /note="identified by match to protein family HMM PF01202"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="YP_006099608.1"
                     /db_xref="GI:386598102"
                     /db_xref="GeneID:12688935"
                     /translation="MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDLWLQSQLNMT
                     VAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCA
                     PVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQV
                     ISEIRSALAQTINC"
     misc_feature    409927..410448
                     /gene="aroL"
                     /locus_tag="ECOK1_0367"
                     /note="Shikimate kinase [Amino acid transport and
                     metabolism]; Region: AroK; COG0703"
                     /db_xref="CDD:223775"
     misc_feature    409936..410397
                     /gene="aroL"
                     /locus_tag="ECOK1_0367"
                     /note="Shikimate kinase (SK) is the fifth enzyme in the
                     shikimate pathway, a seven-step biosynthetic pathway which
                     converts erythrose-4-phosphate to chorismic acid, found in
                     bacteria, fungi and plants. Chorismic acid is a important
                     intermediate in the synthesis...; Region: SK; cd00464"
                     /db_xref="CDD:238260"
     misc_feature    order(409960..409977,410254..410256,410284..410286)
                     /gene="aroL"
                     /locus_tag="ECOK1_0367"
                     /note="ADP binding site [chemical binding]; other site"
                     /db_xref="CDD:238260"
     misc_feature    order(409972..409974,410020..410022,410026..410028)
                     /gene="aroL"
                     /locus_tag="ECOK1_0367"
                     /note="magnesium binding site [ion binding]; other site"
                     /db_xref="CDD:238260"
     misc_feature    order(410026..410028,410098..410100,410107..410109,
                     410158..410166,410341..410343)
                     /gene="aroL"
                     /locus_tag="ECOK1_0367"
                     /note="putative shikimate binding site; other site"
                     /db_xref="CDD:238260"
     gene            410501..410692
                     /locus_tag="ECOK1_0368"
                     /db_xref="GeneID:12688936"
     CDS             410501..410692
                     /locus_tag="ECOK1_0368"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099609.1"
                     /db_xref="GI:386598103"
                     /db_xref="GeneID:12688936"
                     /translation="MPTKPPYPREAYIVTIDKGKPGQTVTWYQLRADHPKPDSLISEH
                     PTAQEAMDAKKRYEDPDKE"
     misc_feature    410501..410689
                     /locus_tag="ECOK1_0368"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10380"
                     /db_xref="CDD:182421"
     gene            410950..411627
                     /gene="aroM"
                     /locus_tag="ECOK1_0369"
                     /db_xref="GeneID:12688937"
     CDS             410950..411627
                     /gene="aroM"
                     /locus_tag="ECOK1_0369"
                     /note="identified by match to protein family HMM PF07302"
                     /codon_start=1
                     /transl_table=11
                     /product="AroM protein"
                     /protein_id="YP_006099610.1"
                     /db_xref="GI:386598104"
                     /db_xref="GeneID:12688937"
                     /translation="MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREE
                     VMAEYAPEAGEDTILTLLNDNHLAHVSRRKVERDLQGVVEVLDNQGYDVIILMSTANI
                     SSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEELLTVQAQKWQILQKPPVFSL
                     GNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFNQRHRDLLQKQLDVPVLLSNVLIAR
                     LAAELLM"
     misc_feature    410950..411621
                     /gene="aroM"
                     /locus_tag="ECOK1_0369"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10481"
                     /db_xref="CDD:182491"
     gene            411699..411983
                     /locus_tag="ECOK1_0370"
                     /db_xref="GeneID:12688938"
     CDS             411699..411983
                     /locus_tag="ECOK1_0370"
                     /note="identified by match to protein family HMM PF06865"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099611.1"
                     /db_xref="GI:386598105"
                     /db_xref="GeneID:12688938"
                     /translation="MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEE
                     MTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL"
     misc_feature    411699..411980
                     /locus_tag="ECOK1_0370"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10579"
                     /db_xref="CDD:182565"
     gene            complement(412087..412230)
                     /locus_tag="ECOK1_0371"
                     /db_xref="GeneID:12688939"
     CDS             complement(412087..412230)
                     /locus_tag="ECOK1_0371"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099612.1"
                     /db_xref="GI:386598106"
                     /db_xref="GeneID:12688939"
                     /translation="MPFGANDHCDFAAMHATIHHLIYLLSSPVPQQYLEIFADIYINL
                     DEL"
     gene            412191..412472
                     /locus_tag="ECOK1_0372"
                     /db_xref="GeneID:12688940"
     CDS             412191..412472
                     /locus_tag="ECOK1_0372"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099613.1"
                     /db_xref="GI:386598107"
                     /db_xref="GeneID:12688940"
                     /translation="MLQSRNDHLRQTALHNAHTPVLLLTTLTEPQERSLAINNSQLAA
                     DVKTAWLKEEPSLLLFVEQPDLSLLRDLVKTGATRKIRSEARHRLEEKQ"
     misc_feature    412227..412469
                     /locus_tag="ECOK1_0372"
                     /note="Protein of unknown function (DUF2773); Region:
                     DUF2773; pfam10971"
                     /db_xref="CDD:151418"
     gene            complement(412630..413541)
                     /locus_tag="ECOK1_0373"
                     /db_xref="GeneID:12688941"
     CDS             complement(412630..413541)
                     /locus_tag="ECOK1_0373"
                     /note="identified by similarity to SP:P36767; match to
                     protein family HMM PF04381"
                     /codon_start=1
                     /transl_table=11
                     /product="putative recombination-associated exonuclease
                     RdgC"
                     /protein_id="YP_006099614.1"
                     /db_xref="GI:386598108"
                     /db_xref="GeneID:12688941"
                     /translation="MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMG
                     WVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKT
                     EKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
                     LPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEE
                     ITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFD
                     ADFILMTGELAALIQNLIEGLGGEAQR"
     misc_feature    complement(412633..413538)
                     /locus_tag="ECOK1_0373"
                     /note="DNA recombination-dependent growth factor C [DNA
                     replication, recombination, and repair]; Region: RdgC;
                     COG2974"
                     /db_xref="CDD:225521"
     gene            413665..414573
                     /gene="mak"
                     /locus_tag="ECOK1_0374"
                     /db_xref="GeneID:12688942"
     CDS             413665..414573
                     /gene="mak"
                     /locus_tag="ECOK1_0374"
                     /EC_number="2.7.1.-"
                     /note="identified by similarity to SP:P23917; match to
                     protein family HMM PF00480"
                     /codon_start=1
                     /transl_table=11
                     /product="manno(fructo)kinase"
                     /protein_id="YP_006099615.1"
                     /db_xref="GI:386598109"
                     /db_xref="GeneID:12688942"
                     /translation="MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIA
                     TLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRL
                     ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPL
                     PWMDEDELRYREEVPCYCGKQGCIETFISGTGFATDYRRLSGHALKGSEIIRLVEESD
                     PVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVPQLIKQFVFGGE
                     CETPVRKAKHGDSSGVRGAAWLWPQE"
     misc_feature    413665..414570
                     /gene="mak"
                     /locus_tag="ECOK1_0374"
                     /note="Transcriptional regulator/sugar kinase
                     [Transcription / Carbohydrate transport and metabolism];
                     Region: NagC; COG1940"
                     /db_xref="CDD:224851"
     misc_feature    413671..414132
                     /gene="mak"
                     /locus_tag="ECOK1_0374"
                     /note="Nucleotide-Binding Domain of the sugar
                     kinase/HSP70/actin superfamily; Region:
                     NBD_sugar-kinase_HSP70_actin; cd00012"
                     /db_xref="CDD:212657"
     misc_feature    order(413680..413691,413695..413697,413701..413703,
                     413977..413979,414049..414060)
                     /gene="mak"
                     /locus_tag="ECOK1_0374"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212657"
     gene            complement(414842..416110)
                     /gene="araJ"
                     /locus_tag="ECOK1_0375"
                     /db_xref="GeneID:12688943"
     CDS             complement(414842..416110)
                     /gene="araJ"
                     /locus_tag="ECOK1_0375"
                     /note="identified by match to protein family HMM PF07690"
                     /codon_start=1
                     /transl_table=11
                     /product="protein araJ"
                     /protein_id="YP_006099616.1"
                     /db_xref="GI:386598110"
                     /db_xref="GeneID:12688943"
                     /translation="MASLVVILQSITLLATVIGSRSGGCDGGMKKVILSLALGTFGLG
                     MAEFGIMGVLTELAHNVGISIPAAGHMISYYALGVVVGAPIIALFSSRYSLKHILLFL
                     VALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIKPGKVTAAVAGM
                     VSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDIRDEAKGKLR
                     EQFHFLRSPAPWLIFAATMFGNAGVFAWFSYVKPYMMFISGFSETAMTFIMMLVGLGM
                     VLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFFGGMKTTSLIFAFICCAGLFAL
                     SAPLQILLLQNAKGGELLGAAGGQIAFNLGSAVGAYCGGMMLTLGLAYNYVALPAALL
                     SFAAMSSLLLYGRYKRQQAADSSVLAKPLG"
     misc_feature    complement(414881..416026)
                     /gene="araJ"
                     /locus_tag="ECOK1_0375"
                     /note="MFS transport protein AraJ; Provisional; Region:
                     PRK10091"
                     /db_xref="CDD:182234"
     misc_feature    complement(414902..416014)
                     /gene="araJ"
                     /locus_tag="ECOK1_0375"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(order(415016..415018,415025..415030,
                     415037..415042,415046..415051,415082..415084,
                     415091..415096,415106..415108,415115..415120,
                     415127..415129,415271..415273,415283..415285,
                     415292..415294,415304..415306,415316..415318,
                     415358..415360,415367..415372,415379..415384,
                     415391..415393,415607..415609,415625..415630,
                     415637..415642,415676..415678,415685..415690,
                     415697..415702,415709..415714,415850..415855,
                     415859..415864,415874..415876,415883..415888,
                     415895..415897,415946..415951,415955..415963,
                     415970..415972))
                     /gene="araJ"
                     /locus_tag="ECOK1_0375"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(416152..419295)
                     /gene="sbcC"
                     /locus_tag="ECOK1_0376"
                     /db_xref="GeneID:12688944"
     CDS             complement(416152..419295)
                     /gene="sbcC"
                     /locus_tag="ECOK1_0376"
                     /note="identified by similarity to SP:P13458; match to
                     protein family HMM PF02463; match to protein family HMM
                     TIGR00618"
                     /codon_start=1
                     /transl_table=11
                     /product="nuclease SbcCD, C subunit"
                     /protein_id="YP_006099617.1"
                     /db_xref="GI:386598111"
                     /db_xref="GeneID:12688944"
                     /translation="MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKT
                     TLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRAR
                     NQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAA
                     FLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQV
                     QSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRLDELQQEGSRRQQALQQALAEEEKA
                     QPQLAALSLAQPARNLRPHWERIAEYSTALAHTRQQIEEVNTRLQSTMALRASIRHHA
                     AKQSAELQQQQQSLNAWLQEHDRLRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHA
                     EQKLNALAAITLTLTADEVASALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQ
                     NVTLEQTQRNAALNEMRHRYKEKTQQLADVKTICEQETRIKTLEAQRAQLQAGQPCPL
                     CGSTSHPAVEAYQALEPGVNQARLLTLEKEVKKLGEEGATLRGQLDALTKQLQRDENE
                     AQSLRQDEQALTQQWQAVTASLNITLQPQDDIQPWLDAQDEHERQLRLLSQRHELQGQ
                     IAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEESWLATRQQEAQSWQHRQN
                     ELTALQNRIQQLTPILETLPQSDELPHSEETVALENWRQVHEQCLALHSQQQTLQQQD
                     VLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQT
                     LVTQTAETLTQHQQHRPGGLSLTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDA
                     DNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQL
                     TRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSH
                     KTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVK
                     KINGLGYSKLESAFAMK"
     misc_feature    complement(416155..419295)
                     /gene="sbcC"
                     /locus_tag="ECOK1_0376"
                     /note="exonuclease subunit SbcC; Provisional; Region:
                     PRK10246"
                     /db_xref="CDD:182330"
     misc_feature    complement(<418810..419295)
                     /gene="sbcC"
                     /locus_tag="ECOK1_0376"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:266551"
     misc_feature    complement(419164..419187)
                     /gene="sbcC"
                     /locus_tag="ECOK1_0376"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(order(418831..418833,419161..419169,
                     419173..419178))
                     /gene="sbcC"
                     /locus_tag="ECOK1_0376"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(418831..418842)
                     /gene="sbcC"
                     /locus_tag="ECOK1_0376"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(416203..>416463)
                     /gene="sbcC"
                     /locus_tag="ECOK1_0376"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:266551"
     misc_feature    complement(416419..416448)
                     /gene="sbcC"
                     /locus_tag="ECOK1_0376"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(416347..416364)
                     /gene="sbcC"
                     /locus_tag="ECOK1_0376"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(416329..416340)
                     /gene="sbcC"
                     /locus_tag="ECOK1_0376"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(416245..416265)
                     /gene="sbcC"
                     /locus_tag="ECOK1_0376"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            complement(419292..420494)
                     /gene="sbcD"
                     /locus_tag="ECOK1_0377"
                     /db_xref="GeneID:12688945"
     CDS             complement(419292..420494)
                     /gene="sbcD"
                     /locus_tag="ECOK1_0377"
                     /note="identified by similarity to SP:P0AG76; match to
                     protein family HMM PF00149; match to protein family HMM
                     TIGR00619"
                     /codon_start=1
                     /transl_table=11
                     /product="nuclease SbcCD subunit D"
                     /protein_id="YP_006099618.1"
                     /db_xref="GI:386598112"
                     /db_xref="GeneID:12688945"
                     /translation="MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQAHQVDAII
                     VAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNT
                     TVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDY
                     YQQHYADACKLRGAQPLPIITTGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYI
                     ALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVT
                     QPMAVLKGDLASITAQLEQWRDISQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVE
                     VLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFATTLH
                     SLAGEHEA"
     misc_feature    complement(419295..420494)
                     /gene="sbcD"
                     /locus_tag="ECOK1_0377"
                     /note="exonuclease subunit SbcD; Provisional; Region:
                     PRK10966"
                     /db_xref="CDD:182871"
     misc_feature    complement(419754..420491)
                     /gene="sbcD"
                     /locus_tag="ECOK1_0377"
                     /note="Mre11 nuclease, N-terminal metallophosphatase
                     domain; Region: MPP_Mre11_N; cd00840"
                     /db_xref="CDD:163616"
     misc_feature    complement(order(419823..419831,419943..419945,
                     420243..420248,420351..420353,420465..420467,
                     420471..420473))
                     /gene="sbcD"
                     /locus_tag="ECOK1_0377"
                     /note="active site"
                     /db_xref="CDD:163616"
     misc_feature    complement(order(419823..419825,419829..419831,
                     419943..419945,420246..420248,420351..420353,
                     420465..420467,420471..420473))
                     /gene="sbcD"
                     /locus_tag="ECOK1_0377"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163616"
     misc_feature    complement(order(420096..420101,420228..420233,
                     420237..420239,420342..420344,420441..420461))
                     /gene="sbcD"
                     /locus_tag="ECOK1_0377"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:163616"
     misc_feature    complement(419367..419675)
                     /gene="sbcD"
                     /locus_tag="ECOK1_0377"
                     /note="Type 5 capsule protein repressor C-terminal domain;
                     Region: SbcD_C; pfam12320"
                     /db_xref="CDD:256978"
     gene            420480..420611
                     /locus_tag="ECOK1_0378"
                     /db_xref="GeneID:12688946"
     CDS             420480..420611
                     /locus_tag="ECOK1_0378"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099619.1"
                     /db_xref="GI:386598113"
                     /db_xref="GeneID:12688946"
                     /translation="MKDAHNGSLAKKHGRDYTQTDVPFAFFCATEINNLKICATSFS"
     gene            420684..421373
                     /gene="phoB"
                     /locus_tag="ECOK1_0379"
                     /db_xref="GeneID:12688947"
     CDS             420684..421373
                     /gene="phoB"
                     /locus_tag="ECOK1_0379"
                     /note="identified by match to protein family HMM PF00072;
                     match to protein family HMM PF00486; match to protein
                     family HMM TIGR02154"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon transcriptional regulatory
                     protein PhoB"
                     /protein_id="YP_006099620.1"
                     /db_xref="GI:386598114"
                     /db_xref="GeneID:12688947"
                     /translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNE
                     PWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDY
                     ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEF
                     KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTV
                     RGTGYRFSTRF"
     misc_feature    420684..421370
                     /gene="phoB"
                     /locus_tag="ECOK1_0379"
                     /note="transcriptional regulator PhoB; Provisional;
                     Region: PRK10161"
                     /db_xref="CDD:182277"
     misc_feature    420699..421043
                     /gene="phoB"
                     /locus_tag="ECOK1_0379"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    order(420708..420713,420840..420842,420864..420866,
                     420930..420932,420987..420989,420996..421001)
                     /gene="phoB"
                     /locus_tag="ECOK1_0379"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    420840..420842
                     /gene="phoB"
                     /locus_tag="ECOK1_0379"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    order(420849..420854,420858..420866)
                     /gene="phoB"
                     /locus_tag="ECOK1_0379"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    420996..421004
                     /gene="phoB"
                     /locus_tag="ECOK1_0379"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    421077..421358
                     /gene="phoB"
                     /locus_tag="ECOK1_0379"
                     /note="Effector domain of response regulator. Bacteria and
                     certain eukaryotes like protozoa and higher plants use
                     two-component signal transduction systems to detect and
                     respond to changes in the environment. The system consists
                     of a sensor histidine kinase and...; Region: trans_reg_C;
                     cd00383"
                     /db_xref="CDD:238225"
     misc_feature    order(421149..421151,421206..421211,421263..421265,
                     421272..421274,421296..421301,421332..421334,
                     421347..421349)
                     /gene="phoB"
                     /locus_tag="ECOK1_0379"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238225"
     gene            421431..422726
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /db_xref="GeneID:12688948"
     CDS             421431..422726
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /EC_number="2.7.3.-"
                     /note="identified by similarity to SP:P08400; match to
                     protein family HMM PF00512; match to protein family HMM
                     PF00989; match to protein family HMM PF02518; match to
                     protein family HMM TIGR00229; match to protein family HMM
                     TIGR02966"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon sensor protein PhoR"
                     /protein_id="YP_006099621.1"
                     /db_xref="GI:386598115"
                     /db_xref="GeneID:12688948"
                     /translation="MLERLSWKRLVLELLLCCLPAFILGAFFGYLPWFLLASVTGLLI
                     WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
                     GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRD
                     FSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
                     LTVLQGYLEMMDEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLLNE
                     KVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTP
                     EGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLA
                     IVKHAVNHHESRLNIESTVGKGTRFSFVIPERLIAKNSD"
     misc_feature    421431..422720
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /note="phosphate regulon sensor protein; Provisional;
                     Region: phoR; PRK11006"
                     /db_xref="CDD:182895"
     misc_feature    421437..421706
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /note="Domain of unknown function (DUF3329); Region:
                     DUF3329; pfam11808"
                     /db_xref="CDD:256638"
     misc_feature    421749..422069
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /note="PAS domain; PAS motifs appear in archaea,
                     eubacteria and eukarya. Probably the most surprising
                     identification of a PAS domain was that in EAG-like
                     K+-channels. PAS domains have been found to bind ligands,
                     and to act as sensors for light and oxygen in...; Region:
                     PAS; cd00130"
                     /db_xref="CDD:238075"
     misc_feature    order(421797..421799,421809..421811,421827..421829,
                     421866..421877,421965..421967,421980..421982)
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /note="putative active site [active]"
                     /db_xref="CDD:238075"
     misc_feature    order(421857..421859,421869..421871,421884..421886,
                     421893..421898,422004..422006,422010..422012)
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /note="heme pocket [chemical binding]; other site"
                     /db_xref="CDD:238075"
     misc_feature    422037..422225
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /note="Histidine Kinase A (dimerization/phosphoacceptor)
                     domain; Histidine Kinase A dimers are formed through
                     parallel association of 2 domains creating 4-helix
                     bundles; usually these domains contain a conserved His
                     residue and are activated via...; Region: HisKA; cd00082"
                     /db_xref="CDD:119399"
     misc_feature    order(422049..422051,422061..422063,422073..422075,
                     422082..422084,422094..422096,422103..422105,
                     422154..422156,422166..422168,422175..422177,
                     422187..422189,422196..422198,422208..422210)
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119399"
     misc_feature    422067..422069
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:119399"
     misc_feature    422382..422693
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    order(422400..422402,422412..422414,422421..422423,
                     422490..422492,422496..422498,422502..422504,
                     422508..422513,422592..422603,422649..422651,
                     422655..422657,422670..422675,422679..422681)
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    422412..422414
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    order(422502..422504,422508..422510,422592..422594,
                     422598..422600)
                     /gene="phoR"
                     /locus_tag="ECOK1_0380"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     gene            423133..424452
                     /gene="brnQ"
                     /locus_tag="ECOK1_0381"
                     /db_xref="GeneID:12688949"
     CDS             423133..424452
                     /gene="brnQ"
                     /locus_tag="ECOK1_0381"
                     /note="identified by similarity to SP:P37011; match to
                     protein family HMM PF05525; match to protein family HMM
                     TIGR00796"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="YP_006099622.1"
                     /db_xref="GI:386598116"
                     /db_xref="GeneID:12688949"
                     /translation="MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
                     AFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRT
                     ATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
                     ILSVAAIIWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
                     TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFG
                     GGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLS
                     QLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAF
                     SDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH"
     misc_feature    423133..424449
                     /gene="brnQ"
                     /locus_tag="ECOK1_0381"
                     /note="branched-chain amino acid transport system 2
                     carrier protein BrnQ; Provisional; Region: PRK15433"
                     /db_xref="CDD:185331"
     gene            424528..425901
                     /gene="proY"
                     /locus_tag="ECOK1_0382"
                     /db_xref="GeneID:12688950"
     CDS             424528..425901
                     /gene="proY"
                     /locus_tag="ECOK1_0382"
                     /note="identified by similarity to SP:P37460; match to
                     protein family HMM PF00324"
                     /codon_start=1
                     /transl_table=11
                     /product="proline-specific permease ProY"
                     /protein_id="YP_006099623.1"
                     /db_xref="GI:386598117"
                     /db_xref="GeneID:12688950"
                     /translation="MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
                     LLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
                     AIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI
                     IIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEII
                     GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQH
                     MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVT
                     VLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVK
                     ALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHD
                     RQLAENQ"
     misc_feature    424528..425892
                     /gene="proY"
                     /locus_tag="ECOK1_0382"
                     /note="putative proline-specific permease; Provisional;
                     Region: proY; PRK10580"
                     /db_xref="CDD:182566"
     misc_feature    424558..>425421
                     /gene="proY"
                     /locus_tag="ECOK1_0382"
                     /note="Solute carrier families 5 and 6-like; solute
                     binding domain; Region: SLC5-6-like_sbd; cl00456"
                     /db_xref="CDD:271490"
     gene            426057..427874
                     /gene="malZ"
                     /locus_tag="ECOK1_0383"
                     /db_xref="GeneID:12688951"
     CDS             426057..427874
                     /gene="malZ"
                     /locus_tag="ECOK1_0383"
                     /EC_number="3.2.1.20"
                     /note="identified by similarity to SP:P21517; match to
                     protein family HMM PF00128"
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin glucosidase"
                     /protein_id="YP_006099624.1"
                     /db_xref="GI:386598118"
                     /db_xref="GeneID:12688951"
                     /translation="MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDN
                     EEMSVPMHKQRSQPQPGVTAWRAAIELSCGQPRRRYSFKLLWHDRQRWFTPQGFSRMP
                     PARLEQFAIDVPDIGPQWAADQIFYQIFPDRFARNLPREAEQDHVYYHHAAGQEIILR
                     DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYR
                     HVDPQFGGDGALLRLRHNTQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPES
                     PWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGW
                     RLDVVHMLGEAGGARNNLQHVAGITEAAKETQPDAYIVGEHFGDARQWLQADVEDAAM
                     NYRGFTFPLWGFLANTDISYDPQQIDAQTCMVWMDNYRAGLSHQQQLRMFNQLDSHDT
                     ARFKTLLGRDVARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQD
                     SALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEV
                     VLPASPLLNVAQWQRKEGHGQLTDGILALPAISATVWMN"
     misc_feature    426057..427847
                     /gene="malZ"
                     /locus_tag="ECOK1_0383"
                     /note="maltodextrin glucosidase; Provisional; Region:
                     PRK10785"
                     /db_xref="CDD:236759"
     misc_feature    426102..426395
                     /gene="malZ"
                     /locus_tag="ECOK1_0383"
                     /note="N-terminal Early set domain associated with the
                     catalytic domain of cyclomaltodextrinase and
                     pullulan-degrading enzymes; Region: E_set_CDase_PDE_N;
                     cd02857"
                     /db_xref="CDD:199887"
     misc_feature    order(426285..426287,426291..426293,426339..426344,
                     426390..426395)
                     /gene="malZ"
                     /locus_tag="ECOK1_0383"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:199887"
     misc_feature    426423..427652
                     /gene="malZ"
                     /locus_tag="ECOK1_0383"
                     /note="Alpha amylase catalytic domain found in
                     cyclomaltodextrinases and related proteins; Region:
                     AmyAc_CMD; cd11338"
                     /db_xref="CDD:200477"
     misc_feature    order(426684..426686,426690..426692,426810..426812,
                     426951..426953,427065..427070,427176..427178,
                     427182..427184,427398..427403,427533..427535,
                     427545..427547)
                     /gene="malZ"
                     /locus_tag="ECOK1_0383"
                     /note="active site"
                     /db_xref="CDD:200477"
     misc_feature    order(426957..426959,427074..427091,427122..427124,
                     427182..427187,427251..427253,427350..427352)
                     /gene="malZ"
                     /locus_tag="ECOK1_0383"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:200477"
     misc_feature    order(427065..427067,427176..427178,427401..427403)
                     /gene="malZ"
                     /locus_tag="ECOK1_0383"
                     /note="catalytic site [active]"
                     /db_xref="CDD:200477"
     gene            complement(427879..428460)
                     /gene="acpH"
                     /locus_tag="ECOK1_0384"
                     /db_xref="GeneID:12688952"
     CDS             complement(427879..428460)
                     /gene="acpH"
                     /locus_tag="ECOK1_0384"
                     /EC_number="3.1.4.14"
                     /note="identified by match to protein family HMM PF04336"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein phosphodiesterase"
                     /protein_id="YP_006099625.1"
                     /db_xref="GI:386598119"
                     /db_xref="GeneID:12688952"
                     /translation="MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHM
                     HRRIDVLTDNLPEVREAREWFRNETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFT
                     CYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQSVLNGMASRRPRLDALR
                     DSWYDLDAHYDALETRFWQFYPRMMEQASRKAL"
     misc_feature    complement(427882..428460)
                     /gene="acpH"
                     /locus_tag="ECOK1_0384"
                     /note="acyl carrier protein phosphodiesterase;
                     Provisional; Region: PRK10045"
                     /db_xref="CDD:182207"
     gene            428679..429749
                     /gene="queA"
                     /locus_tag="ECOK1_0385"
                     /db_xref="GeneID:12688953"
     CDS             428679..429749
                     /gene="queA"
                     /locus_tag="ECOK1_0385"
                     /EC_number="5.-.-.-"
                     /note="identified by match to protein family HMM PF02547;
                     match to protein family HMM TIGR00113"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine--tRNA
                     ribosyltransferase-isomerase"
                     /protein_id="YP_006099626.1"
                     /db_xref="GI:386598120"
                     /db_xref="GeneID:12688953"
                     /translation="MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFT
                     DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDEKRILAHIRASKAPK
                     PGAELLLGDDESINATMTARHGALFEVEFNDDRLVLDILNSIGHIPLPPYIDRPDEDA
                     DRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVD
                     TIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPF
                     FDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRF
                     FSYGDAMFITYNPQAINERVGE"
     misc_feature    428679..429710
                     /gene="queA"
                     /locus_tag="ECOK1_0385"
                     /note="S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase; Provisional; Region: queA;
                     PRK00147"
                     /db_xref="CDD:234666"
     gene            429804..430931
                     /gene="tgt"
                     /locus_tag="ECOK1_0386"
                     /db_xref="GeneID:12688954"
     CDS             429804..430931
                     /gene="tgt"
                     /locus_tag="ECOK1_0386"
                     /EC_number="2.4.2.29"
                     /note="identified by match to protein family HMM PF01702;
                     match to protein family HMM TIGR00430; match to protein
                     family HMM TIGR00449"
                     /codon_start=1
                     /transl_table=11
                     /product="queuine tRNA-ribosyltransferase"
                     /protein_id="YP_006099627.1"
                     /db_xref="GI:386598121"
                     /db_xref="GeneID:12688954"
                     /translation="MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPE
                     EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
                     KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
                     MSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVG
                     EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
                     LFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
                     LRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD"
     misc_feature    429804..430895
                     /gene="tgt"
                     /locus_tag="ECOK1_0386"
                     /note="queuine tRNA-ribosyltransferase; Provisional;
                     Region: tgt; PRK00112"
                     /db_xref="CDD:234642"
     misc_feature    429810..430919
                     /gene="tgt"
                     /locus_tag="ECOK1_0386"
                     /note="Queuine/archaeosine tRNA-ribosyltransferase
                     [Translation, ribosomal structure and biogenesis]; Region:
                     Tgt; COG0343"
                     /db_xref="CDD:223420"
     gene            430954..431286
                     /gene="yajC"
                     /locus_tag="ECOK1_0387"
                     /db_xref="GeneID:12688955"
     CDS             430954..431286
                     /gene="yajC"
                     /locus_tag="ECOK1_0387"
                     /note="identified by match to protein family HMM PF02699;
                     match to protein family HMM TIGR00739"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="YP_006099628.1"
                     /db_xref="GI:386598122"
                     /db_xref="GeneID:12688955"
                     /translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
                     RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVL
                     PKGTMKAL"
     misc_feature    430960..431283
                     /gene="yajC"
                     /locus_tag="ECOK1_0387"
                     /note="preprotein translocase subunit YajC; Validated;
                     Region: yajC; PRK05585"
                     /db_xref="CDD:235518"
     gene            431314..433161
                     /gene="secD"
                     /locus_tag="ECOK1_0388"
                     /db_xref="GeneID:12688956"
     CDS             431314..433161
                     /gene="secD"
                     /locus_tag="ECOK1_0388"
                     /note="identified by match to protein family HMM PF02355;
                     match to protein family HMM PF07549; match to protein
                     family HMM TIGR00916; match to protein family HMM
                     TIGR01129"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export membrane protein SecD"
                     /protein_id="YP_006099629.1"
                     /db_xref="GI:386598123"
                     /db_xref="GeneID:12688956"
                     /translation="MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVA
                     ASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVA
                     LNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
                     KGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDAR
                     LSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGAT
                     ATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQD
                     EYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEV
                     INIANIQSRLGNSFRITGINNPSEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNI
                     EQGLEACLAGLLVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIA
                     GIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVII
                     LYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI"
     misc_feature    431317..431622
                     /gene="secD"
                     /locus_tag="ECOK1_0388"
                     /note="SecD export protein N-terminal TM region; Region:
                     SecD-TM1; pfam13721"
                     /db_xref="CDD:258018"
     misc_feature    431335..433158
                     /gene="secD"
                     /locus_tag="ECOK1_0388"
                     /note="preprotein translocase subunit SecD; Reviewed;
                     Region: secD; PRK05812"
                     /db_xref="CDD:235615"
     misc_feature    431650..431742
                     /gene="secD"
                     /locus_tag="ECOK1_0388"
                     /note="SecD/SecF GG Motif; Region: Sec_GG; pfam07549"
                     /db_xref="CDD:254281"
     misc_feature    432610..433095
                     /gene="secD"
                     /locus_tag="ECOK1_0388"
                     /note="protein-export membrane protein, SecD/SecF family;
                     Region: 2A0604s01; TIGR00916"
                     /db_xref="CDD:233183"
     gene            433172..434143
                     /gene="secF"
                     /locus_tag="ECOK1_0389"
                     /db_xref="GeneID:12688957"
     CDS             433172..434143
                     /gene="secF"
                     /locus_tag="ECOK1_0389"
                     /note="identified by match to protein family HMM PF02355;
                     match to protein family HMM PF07549; match to protein
                     family HMM TIGR00916; match to protein family HMM
                     TIGR00966"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export membrane protein SecF"
                     /protein_id="YP_006099630.1"
                     /db_xref="GI:386598124"
                     /db_xref="GeneID:12688957"
                     /translation="MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVR
                     GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAE
                     GETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
                     VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
                     DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLT
                     MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
     misc_feature    433211..434089
                     /gene="secF"
                     /locus_tag="ECOK1_0389"
                     /note="preprotein translocase subunit SecF; Reviewed;
                     Region: secF; PRK13022"
                     /db_xref="CDD:237275"
     misc_feature    433283..433375
                     /gene="secF"
                     /locus_tag="ECOK1_0389"
                     /note="SecD/SecF GG Motif; Region: Sec_GG; pfam07549"
                     /db_xref="CDD:254281"
     misc_feature    433511..434077
                     /gene="secF"
                     /locus_tag="ECOK1_0389"
                     /note="Protein export membrane protein; Region: SecD_SecF;
                     pfam02355"
                     /db_xref="CDD:216990"
     gene            434273..434620
                     /locus_tag="ECOK1_0390"
                     /db_xref="GeneID:12688958"
     CDS             434273..434620
                     /locus_tag="ECOK1_0390"
                     /note="identified by match to protein family HMM PF01844"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease family protein"
                     /protein_id="YP_006099631.1"
                     /db_xref="GI:386598125"
                     /db_xref="GeneID:12688958"
                     /translation="MAIIPKNYARLESDYREKALKIYPWVCGRCSREFVYSNLRELTV
                     HHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYN
                     PFADLKAMMNKKK"
     misc_feature    434312..434491
                     /locus_tag="ECOK1_0390"
                     /note="HNH nucleases; HNH endonuclease signature which is
                     found in viral, prokaryotic, and eukaryotic proteins. The
                     alignment includes members of the large group of homing
                     endonucleases, yeast intron 1 protein, MutS, as well as
                     bacterial colicins, pyocins, and...; Region: HNHc;
                     cd00085"
                     /db_xref="CDD:238038"
     misc_feature    order(434399..434401,434405..434413,434417..434419,
                     434450..434455,434465..434470,434477..434479,
                     434489..434491)
                     /locus_tag="ECOK1_0390"
                     /note="active site"
                     /db_xref="CDD:238038"
     gene            complement(434658..435542)
                     /gene="tsx"
                     /locus_tag="ECOK1_0391"
                     /db_xref="GeneID:12688959"
     CDS             complement(434658..435542)
                     /gene="tsx"
                     /locus_tag="ECOK1_0391"
                     /note="identified by similarity to SP:P40786; match to
                     protein family HMM PF03502"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-specific channel-forming protein"
                     /protein_id="YP_006099632.1"
                     /db_xref="GI:386598126"
                     /db_xref="GeneID:12688959"
                     /translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGS
                     YHTRFGPQLRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEI
                     EPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMS
                     LSMNVYAKYQWQNYGAANENEWDGYRFKVKYFVPITDLWGGQLSYIGFTNFDWGSDLG
                     DDSGYANNGIKTRTNNSIASSHILALNYDHWHYSVVARYWHNGGQWNDDAELNFGNGN
                     FNVRSTGWGGYLVVGYNF"
     misc_feature    complement(434661..435542)
                     /gene="tsx"
                     /locus_tag="ECOK1_0391"
                     /note="nucleoside-specific channel-forming protein Tsx;
                     Provisional; Region: PRK15106"
                     /db_xref="CDD:237911"
     gene            complement(435840..436379)
                     /locus_tag="ECOK1_0392"
                     /db_xref="GeneID:12688960"
     CDS             complement(435840..436379)
                     /locus_tag="ECOK1_0392"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipoprotein"
                     /protein_id="YP_006099633.1"
                     /db_xref="GI:386598127"
                     /db_xref="GeneID:12688960"
                     /translation="MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLN
                     KETVKITQQNRLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDTDGTTLTLR
                     IQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKG
                     MSVDQLGFVRIHDIQPVMQ"
     misc_feature    complement(435843..436379)
                     /locus_tag="ECOK1_0392"
                     /note="hypothetical protein; Provisional; Region:
                     PRK11530"
                     /db_xref="CDD:236923"
     gene            436530..436979
                     /gene="nrdR"
                     /locus_tag="ECOK1_0393"
                     /db_xref="GeneID:12688961"
     CDS             436530..436979
                     /gene="nrdR"
                     /locus_tag="ECOK1_0393"
                     /note="identified by match to protein family HMM PF03477;
                     match to protein family HMM TIGR00244"
                     /codon_start=1
                     /transl_table=11
                     /product="NrdR family transcriptional regulator"
                     /protein_id="YP_006099634.1"
                     /db_xref="GI:386598128"
                     /db_xref="GeneID:12688961"
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVA
                     ELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGERE
                     VPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED"
     misc_feature    436530..436970
                     /gene="nrdR"
                     /locus_tag="ECOK1_0393"
                     /note="transcriptional regulator NrdR; Validated; Region:
                     nrdR; PRK00464"
                     /db_xref="CDD:234774"
     misc_feature    436674..436940
                     /gene="nrdR"
                     /locus_tag="ECOK1_0393"
                     /note="ATP cone domain; Region: ATP-cone; pfam03477"
                     /db_xref="CDD:251987"
     gene            436983..438086
                     /gene="ribD"
                     /locus_tag="ECOK1_0394"
                     /db_xref="GeneID:12688962"
     CDS             436983..438086
                     /gene="ribD"
                     /locus_tag="ECOK1_0394"
                     /EC_number="3.5.4.26"
                     /EC_number="1.1.1.193"
                     /note="identified by similarity to SP:P25539; match to
                     protein family HMM PF00383; match to protein family HMM
                     PF01872; match to protein family HMM TIGR00227; match to
                     protein family HMM TIGR00326"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibD"
                     /protein_id="YP_006099635.1"
                     /db_xref="GI:386598129"
                     /db_xref="GeneID:12688962"
                     /translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQ
                     RAGEPHAEVQALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVAAMQD
                     PNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
                     TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWSELDEQTQGL
                     YPQQNLRQPVRIVIDSQNRVTPEHRIVQQPGETWFARTQEDSREWPETVRTLLIPEHK
                     GHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGNDARGLC
                     TLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA"
     misc_feature    436983..438083
                     /gene="ribD"
                     /locus_tag="ECOK1_0394"
                     /note="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase; Provisional; Region: ribD; PRK10786"
                     /db_xref="CDD:182729"
     misc_feature    437001..437339
                     /gene="ribD"
                     /locus_tag="ECOK1_0394"
                     /note="Riboflavin-specific deaminase. Riboflavin
                     biosynthesis protein RibD
                     (Diaminohydroxyphosphoribosylaminopyrimidine deaminase)
                     catalyzes the deamination of
                     2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone
                     5'-phosphate, which is an intermediate step in the...;
                     Region: Riboflavin_deaminase-reductase; cd01284"
                     /db_xref="CDD:238611"
     misc_feature    order(437130..437138,437202..437207,437232..437234)
                     /gene="ribD"
                     /locus_tag="ECOK1_0394"
                     /note="catalytic motif [active]"
                     /db_xref="CDD:238611"
     misc_feature    order(437130..437132,437136..437138,437205..437207,
                     437232..437234)
                     /gene="ribD"
                     /locus_tag="ECOK1_0394"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:238611"
     misc_feature    437415..438080
                     /gene="ribD"
                     /locus_tag="ECOK1_0394"
                     /note="riboflavin-specific deaminase C-terminal domain;
                     Region: ribD_Cterm; TIGR00227"
                     /db_xref="CDD:129330"
     gene            438175..438645
                     /gene="ribH"
                     /locus_tag="ECOK1_0395"
                     /db_xref="GeneID:12688963"
     CDS             438175..438645
                     /gene="ribH"
                     /locus_tag="ECOK1_0395"
                     /EC_number="6.3.3.-"
                     /note="identified by similarity to SP:P61714; match to
                     protein family HMM PF00885; match to protein family HMM
                     TIGR00114"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="YP_006099636.1"
                     /db_xref="GI:386598130"
                     /db_xref="GeneID:12688963"
                     /translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQV
                     KDENITIVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLA
                     HVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     misc_feature    438217..438618
                     /gene="ribH"
                     /locus_tag="ECOK1_0395"
                     /note="lumazine synthase (6,7-dimethyl-8-ribityllumazine
                     synthase, LS), catalyzes the penultimate step in the
                     biosynthesis of riboflavin (vitamin B2); type-I; Region:
                     Lumazine_synthase-I; cd09209"
                     /db_xref="CDD:187742"
     misc_feature    order(438220..438222,438238..438240,438328..438339,
                     438346..438351,438355..438363,438367..438375,
                     438379..438381,438391..438393,438424..438426,
                     438430..438435,438439..438441,438445..438450,
                     438454..438462,438466..438474,438478..438492,
                     438499..438504,438514..438516,438520..438522,
                     438526..438528,438532..438534,438544..438546,
                     438556..438558,438580..438582,438589..438591,
                     438601..438603,438610..438615)
                     /gene="ribH"
                     /locus_tag="ECOK1_0395"
                     /note="homopentamer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187742"
     misc_feature    order(438238..438243,438340..438351,438412..438429,
                     438433..438435,438439..438444,438511..438525,
                     438556..438558,438580..438582,438589..438591)
                     /gene="ribH"
                     /locus_tag="ECOK1_0395"
                     /note="active site"
                     /db_xref="CDD:187742"
     gene            438665..439084
                     /gene="nusB"
                     /locus_tag="ECOK1_0396"
                     /db_xref="GeneID:12688964"
     CDS             438665..439084
                     /gene="nusB"
                     /locus_tag="ECOK1_0396"
                     /note="identified by match to protein family HMM PF01029;
                     match to protein family HMM TIGR01951"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusB"
                     /protein_id="YP_006099637.1"
                     /db_xref="GI:386598131"
                     /db_xref="GeneID:12688964"
                     /translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
                     VLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKV
                     AINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
     misc_feature    438695..439066
                     /gene="nusB"
                     /locus_tag="ECOK1_0396"
                     /note="Transcription termination factor NusB (N
                     protein-Utilization Substance B). NusB plays a key role in
                     the regulation of ribosomal RNA biosynthesis in eubacteria
                     by modulating the efficiency of transcriptional
                     antitermination. NusB along with other Nus...; Region:
                     Terminator_NusB; cd00619"
                     /db_xref="CDD:238342"
     gene            439162..440139
                     /gene="thiL"
                     /locus_tag="ECOK1_0397"
                     /db_xref="GeneID:12688965"
     CDS             439162..440139
                     /gene="thiL"
                     /locus_tag="ECOK1_0397"
                     /EC_number="2.7.4.16"
                     /note="identified by similarity to SP:P77785; match to
                     protein family HMM PF02769; match to protein family HMM
                     TIGR01379"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-monophosphate kinase"
                     /protein_id="YP_006099638.1"
                     /db_xref="GI:386598132"
                     /db_xref="GeneID:12688965"
                     /translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAI
                     STDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLES
                     FSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGT
                     PGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLI
                     SDLGHIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNR
                     GALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTLDWKGYDHFATP"
     misc_feature    439162..440127
                     /gene="thiL"
                     /locus_tag="ECOK1_0397"
                     /note="thiamine monophosphate kinase; Provisional; Region:
                     PRK05731"
                     /db_xref="CDD:235583"
     misc_feature    439171..440052
                     /gene="thiL"
                     /locus_tag="ECOK1_0397"
                     /note="ThiL (Thiamine-monophosphate kinase) plays a dual
                     role in de novo biosynthesis and in salvage of exogenous
                     thiamine. Thiamine salvage occurs in two steps, with
                     thiamine kinase catalyzing the formation of thiamine
                     phosphate, and ThiL catalyzing the...; Region: ThiL;
                     cd02194"
                     /db_xref="CDD:100030"
     misc_feature    order(439186..439188,439243..439251,439384..439386,
                     439423..439425,439471..439473,439519..439527,
                     439597..439599,439795..439797,439801..439806)
                     /gene="thiL"
                     /locus_tag="ECOK1_0397"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:100030"
     misc_feature    order(439195..439197,439252..439254,439297..439305,
                     439309..439311,439471..439473,439516..439518,
                     439525..439536,439552..439554,439558..439560)
                     /gene="thiL"
                     /locus_tag="ECOK1_0397"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:100030"
     gene            440117..440635
                     /gene="pgpA"
                     /locus_tag="ECOK1_0398"
                     /db_xref="GeneID:12688966"
     CDS             440117..440635
                     /gene="pgpA"
                     /locus_tag="ECOK1_0398"
                     /note="identified by match to protein family HMM PF04608"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="YP_006099639.1"
                     /db_xref="GI:386598133"
                     /db_xref="GeneID:12688966"
                     /translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLA
                     AIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
                     MALPTNDWQWVTAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILY
                     FIGHHWPLGILS"
     misc_feature    440177..440602
                     /gene="pgpA"
                     /locus_tag="ECOK1_0398"
                     /note="Phosphatidylglycerophosphatase A; a bacterial
                     membrane-associated enzyme involved in lipid metabolism;
                     Region: PgpA; cd06971"
                     /db_xref="CDD:133477"
     misc_feature    order(440186..440188,440252..440254,440303..440305,
                     440312..440317,440324..440329,440375..440377,
                     440384..440392,440399..440404,440408..440413,
                     440420..440422,440453..440461,440465..440473,
                     440477..440482,440486..440491,440600..440602)
                     /gene="pgpA"
                     /locus_tag="ECOK1_0398"
                     /note="tetramer interfaces [polypeptide binding]; other
                     site"
                     /db_xref="CDD:133477"
     misc_feature    order(440384..440386,440393..440398,440546..440548,
                     440555..440560)
                     /gene="pgpA"
                     /locus_tag="ECOK1_0398"
                     /note="binuclear metal-binding site [ion binding]; other
                     site"
                     /db_xref="CDD:133477"
     gene            complement(440689..441663)
                     /locus_tag="ECOK1_0399"
                     /db_xref="GeneID:12688967"
     CDS             complement(440689..441663)
                     /locus_tag="ECOK1_0399"
                     /note="identified by match to protein family HMM PF00248"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase, aldo/keto reductase family"
                     /protein_id="YP_006099640.1"
                     /db_xref="GI:386598134"
                     /db_xref="GeneID:12688967"
                     /translation="MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPII
                     KRALEGGINFFDTANSYSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSR
                     AQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
                     ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGR
                     LTRPWGETTARLVSDEVGKNLYQESNENDAQIVERLTGVSEELGATRAQVALAWLLSK
                     PGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPVVGFK"
     misc_feature    complement(440728..441657)
                     /locus_tag="ECOK1_0399"
                     /note="Aldo-keto reductases (AKRs) are a superfamily of
                     soluble NAD(P)(H) oxidoreductases whose chief purpose is
                     to reduce aldehydes and ketones to primary and secondary
                     alcohols. AKRs are present in all phyla and are of
                     importance to both health and industrial...; Region:
                     Aldo_ket_red; cd06660"
                     /db_xref="CDD:119408"
     misc_feature    complement(440728..441657)
                     /locus_tag="ECOK1_0399"
                     /note="voltage-dependent potassium channel beta subunit,
                     animal; Region: Kv_beta; TIGR01293"
                     /db_xref="CDD:213602"
     misc_feature    complement(order(440779..440784,440791..440793,
                     440806..440817,440866..440868,441016..441033,
                     441115..441117,441190..441195,441280..441285,
                     441400..441402,441481..441483,441496..441498,
                     441601..441609))
                     /locus_tag="ECOK1_0399"
                     /note="active site"
                     /db_xref="CDD:119408"
     misc_feature    complement(order(441283..441285,441400..441402,
                     441481..441483,441496..441498))
                     /locus_tag="ECOK1_0399"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:119408"
     gene            complement(441718..443580)
                     /gene="dxs"
                     /locus_tag="ECOK1_0400"
                     /db_xref="GeneID:12688968"
     CDS             complement(441718..443580)
                     /gene="dxs"
                     /locus_tag="ECOK1_0400"
                     /EC_number="2.2.1.7"
                     /note="identified by similarity to SP:P77488; match to
                     protein family HMM PF02779; match to protein family HMM
                     PF02780; match to protein family HMM TIGR00204"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="YP_006099641.1"
                     /db_xref="GI:386598135"
                     /db_xref="GeneID:12688968"
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
                     RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
                     GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMA
                     FEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSG
                     VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQ
                     FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAA
                     KDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIY
                     STFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
                     PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAI
                     LNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAG
                     SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA"
     misc_feature    complement(441721..443550)
                     /gene="dxs"
                     /locus_tag="ECOK1_0400"
                     /note="1-deoxy-D-xylulose-5-phosphate synthase; Region:
                     dxs; TIGR00204"
                     /db_xref="CDD:129308"
     misc_feature    complement(442717..443442)
                     /gene="dxs"
                     /locus_tag="ECOK1_0400"
                     /note="Thiamine pyrophosphate (TPP) family, DXS subfamily,
                     TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate
                     synthase (DXS) is a regulatory enzyme of the
                     mevalonate-independent pathway involved in terpenoid
                     biosynthesis. Terpeniods are plant natural products...;
                     Region: TPP_DXS; cd02007"
                     /db_xref="CDD:238965"
     misc_feature    complement(order(443032..443034,443038..443040,
                     443119..443130,443212..443214))
                     /gene="dxs"
                     /locus_tag="ECOK1_0400"
                     /note="TPP-binding site; other site"
                     /db_xref="CDD:238965"
     misc_feature    complement(442147..442614)
                     /gene="dxs"
                     /locus_tag="ECOK1_0400"
                     /note="Pyrimidine (PYR) binding domain of
                     1-deoxy-D-xylulose-5-phosphate synthase (DXS),
                     transketolase (TK), and related proteins; Region:
                     TPP_PYR_DXS_TK_like; cd07033"
                     /db_xref="CDD:132916"
     misc_feature    complement(order(442174..442176,442240..442245,
                     442291..442293,442300..442302,442375..442380,
                     442387..442389,442441..442449,442453..442458,
                     442465..442482,442486..442488,442495..442497,
                     442546..442548,442564..442566,442570..442572))
                     /gene="dxs"
                     /locus_tag="ECOK1_0400"
                     /note="PYR/PP interface [polypeptide binding]; other site"
                     /db_xref="CDD:132916"
     misc_feature    complement(order(442249..442251,442255..442260,
                     442264..442269,442294..442296,442300..442302,
                     442381..442383,442387..442392,442471..442479,
                     442486..442488,442546..442548))
                     /gene="dxs"
                     /locus_tag="ECOK1_0400"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:132916"
     misc_feature    complement(order(442387..442389,442396..442398,
                     442471..442473,442477..442479))
                     /gene="dxs"
                     /locus_tag="ECOK1_0400"
                     /note="TPP binding site [chemical binding]; other site"
                     /db_xref="CDD:132916"
     misc_feature    complement(441748..442098)
                     /gene="dxs"
                     /locus_tag="ECOK1_0400"
                     /note="Transketolase, C-terminal domain; Region:
                     Transketolase_C; pfam02780"
                     /db_xref="CDD:251527"
     gene            complement(443605..444504)
                     /gene="ispA"
                     /locus_tag="ECOK1_0401"
                     /db_xref="GeneID:12688969"
     CDS             complement(443605..444504)
                     /gene="ispA"
                     /locus_tag="ECOK1_0401"
                     /EC_number="2.5.1.10"
                     /note="identified by similarity to SP:P22939; match to
                     protein family HMM PF00348"
                     /codon_start=1
                     /transl_table=11
                     /product="geranyltranstransferase"
                     /protein_id="YP_006099642.1"
                     /db_xref="GI:386598136"
                     /db_xref="GeneID:12688969"
                     /translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGG
                     KRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
                     VKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQAL
                     DLDAEGKRVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLA
                     FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQ
                     LAEQSLDTSALEALADYIIQRNK"
     misc_feature    complement(443614..444420)
                     /gene="ispA"
                     /locus_tag="ECOK1_0401"
                     /note="Trans-Isoprenyl Diphosphate Synthases,
                     head-to-tail; Region: Trans_IPPS_HT; cd00685"
                     /db_xref="CDD:173833"
     misc_feature    complement(order(443764..443766,443779..443781,
                     443794..443796,443824..443826,443833..443838,
                     443950..443952,443959..443964,444022..444024,
                     444031..444033,444217..444222,444256..444258,
                     444262..444270,444277..444279))
                     /gene="ispA"
                     /locus_tag="ECOK1_0401"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173833"
     misc_feature    complement(444256..444270)
                     /gene="ispA"
                     /locus_tag="ECOK1_0401"
                     /note="chain length determination region; other site"
                     /db_xref="CDD:173833"
     misc_feature    complement(order(443758..443772,443779..443796,
                     443812..443817,444187..444225,444253..444255))
                     /gene="ispA"
                     /locus_tag="ECOK1_0401"
                     /note="active site lid residues [active]"
                     /db_xref="CDD:173833"
     misc_feature    complement(order(443764..443766,443779..443781,
                     443794..443796,443824..443826,443833..443838,
                     443962..443964,444022..444024,444217..444222))
                     /gene="ispA"
                     /locus_tag="ECOK1_0401"
                     /note="substrate-Mg2+ binding site; other site"
                     /db_xref="CDD:173833"
     misc_feature    complement(order(443833..443838,443962..443964,
                     444217..444222))
                     /gene="ispA"
                     /locus_tag="ECOK1_0401"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:173833"
     misc_feature    complement(order(443962..443964,444022..444024,
                     444217..444222))
                     /gene="ispA"
                     /locus_tag="ECOK1_0401"
                     /note="aspartate-rich region 1; other site"
                     /db_xref="CDD:173833"
     misc_feature    complement(order(443764..443766,443779..443781,
                     443794..443796,443824..443826,443833..443838))
                     /gene="ispA"
                     /locus_tag="ECOK1_0401"
                     /note="aspartate-rich region 2; other site"
                     /db_xref="CDD:173833"
     gene            complement(444504..444746)
                     /gene="xseB"
                     /locus_tag="ECOK1_0402"
                     /db_xref="GeneID:12688970"
     CDS             complement(444504..444746)
                     /gene="xseB"
                     /locus_tag="ECOK1_0402"
                     /EC_number="3.1.11.6"
                     /note="identified by similarity to SP:P0A8H2; match to
                     protein family HMM PF02609; match to protein family HMM
                     TIGR01280"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="YP_006099643.1"
                     /db_xref="GI:386598137"
                     /db_xref="GeneID:12688970"
                     /translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQ
                     LARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
     misc_feature    complement(444513..444746)
                     /gene="xseB"
                     /locus_tag="ECOK1_0402"
                     /note="exodeoxyribonuclease VII small subunit;
                     Provisional; Region: PRK00977"
                     /db_xref="CDD:179195"
     gene            444952..446400
                     /gene="thiI"
                     /locus_tag="ECOK1_0403"
                     /db_xref="GeneID:12688971"
     CDS             444952..446400
                     /gene="thiI"
                     /locus_tag="ECOK1_0403"
                     /note="identified by similarity to SP:P77718; match to
                     protein family HMM PF02568; match to protein family HMM
                     PF02926; match to protein family HMM TIGR00342"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis/tRNA modification protein
                     ThiI"
                     /protein_id="YP_006099644.1"
                     /db_xref="GI:386598138"
                     /db_xref="GeneID:12688971"
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
                     RHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQL
                     EGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPEVTVHLEVEDDRLL
                     LIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEI
                     GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVA
                     ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
                     DFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTE
                     QEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQSK
                     TWLLWCERGVMSRLQALYLREQGFNNVKVYRP"
     misc_feature    444952..446397
                     /gene="thiI"
                     /locus_tag="ECOK1_0403"
                     /note="tRNA s(4)U8 sulfurtransferase; Provisional; Region:
                     PRK01269"
                     /db_xref="CDD:234932"
     misc_feature    444955..445461
                     /gene="thiI"
                     /locus_tag="ECOK1_0403"
                     /note="THUMP domain of thiamine biosynthesis protein ThiI;
                     Region: THUMP_ThiI; cd11716"
                     /db_xref="CDD:212585"
     misc_feature    445489..446010
                     /gene="thiI"
                     /locus_tag="ECOK1_0403"
                     /note="ThiI is required for thiazole synthesis in the
                     thiamine biosynthesis pathway. It belongs to the Adenosine
                     Nucleotide Hydrolysis suoerfamily and predicted to bind to
                     Adenosine nucleotide; Region: ThiI; cd01712"
                     /db_xref="CDD:238845"
     misc_feature    order(445498..445506,445510..445521,445576..445578,
                     445582..445584)
                     /gene="thiI"
                     /locus_tag="ECOK1_0403"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238845"
     misc_feature    446164..446394
                     /gene="thiI"
                     /locus_tag="ECOK1_0403"
                     /note="Rhodanese Homology Domain (RHOD); an alpha beta
                     fold domain found duplicated in the rhodanese protein. The
                     cysteine containing enzymatically active version of the
                     domain is also found in the Cdc25 class of protein
                     phosphatases and a variety of proteins...; Region: RHOD;
                     cd00158"
                     /db_xref="CDD:238089"
     misc_feature    446317..446319
                     /gene="thiI"
                     /locus_tag="ECOK1_0403"
                     /note="active site residue [active]"
                     /db_xref="CDD:238089"
     gene            complement(446454..447044)
                     /gene="thiJ"
                     /locus_tag="ECOK1_0404"
                     /db_xref="GeneID:12688972"
     CDS             complement(446454..447044)
                     /gene="thiJ"
                     /locus_tag="ECOK1_0404"
                     /note="identified by match to protein family HMM PF01965;
                     match to protein family HMM TIGR01383"
                     /codon_start=1
                     /transl_table=11
                     /product="protein ThiJ"
                     /protein_id="YP_006099645.1"
                     /db_xref="GI:386598139"
                     /db_xref="GeneID:12688972"
                     /translation="MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLA
                     ITCSRGVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIV
                     AAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWQDKRVVWDARVKLLTSQGPGT
                     AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     misc_feature    complement(446457..447044)
                     /gene="thiJ"
                     /locus_tag="ECOK1_0404"
                     /note="oxidative-stress-resistance chaperone; Provisional;
                     Region: PRK11574"
                     /db_xref="CDD:183210"
     misc_feature    complement(446529..447032)
                     /gene="thiJ"
                     /locus_tag="ECOK1_0404"
                     /note="Type 1 glutamine amidotransferase (GATase1)-like
                     domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135"
                     /db_xref="CDD:153229"
     misc_feature    complement(446727..446729)
                     /gene="thiJ"
                     /locus_tag="ECOK1_0404"
                     /note="conserved cys residue [active]"
                     /db_xref="CDD:153229"
     gene            complement(447007..447918)
                     /gene="panE"
                     /locus_tag="ECOK1_0405"
                     /db_xref="GeneID:12688973"
     CDS             complement(447007..447918)
                     /gene="panE"
                     /locus_tag="ECOK1_0405"
                     /EC_number="1.1.1.169"
                     /note="identified by match to protein family HMM PF02558;
                     match to protein family HMM PF08546; match to protein
                     family HMM TIGR00745"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="YP_006099646.1"
                     /db_xref="GI:386598140"
                     /db_xref="GeneID:12688973"
                     /translation="MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVET
                     DGSIFNESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGT
                     IEELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVL
                     PDVAWHNNIRAELWRKLAVNCVINPLTATWNCPNGELRHHPQEIMQICEEVAAVIERE
                     GHHTSAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVP
                     ENTRLFEMVKRKESEYERIGTGLPRPW"
     misc_feature    complement(447034..447918)
                     /gene="panE"
                     /locus_tag="ECOK1_0405"
                     /note="2-dehydropantoate 2-reductase; Reviewed; Region:
                     PRK06522"
                     /db_xref="CDD:235821"
     misc_feature    complement(447487..447912)
                     /gene="panE"
                     /locus_tag="ECOK1_0405"
                     /note="Ketopantoate reductase PanE/ApbA; Region: ApbA;
                     pfam02558"
                     /db_xref="CDD:251374"
     misc_feature    complement(447052..447417)
                     /gene="panE"
                     /locus_tag="ECOK1_0405"
                     /note="Ketopantoate reductase PanE/ApbA C terminal;
                     Region: ApbA_C; pfam08546"
                     /db_xref="CDD:254871"
     gene            448086..448577
                     /locus_tag="ECOK1_0406"
                     /db_xref="GeneID:12688974"
     CDS             448086..448577
                     /locus_tag="ECOK1_0406"
                     /note="identified by similarity to SP:P59561; match to
                     protein family HMM PF04461"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099647.1"
                     /db_xref="GI:386598141"
                     /db_xref="GeneID:12688974"
                     /translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDA
                     SKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGI
                     ESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKN
                     FRD"
     misc_feature    448089..448571
                     /locus_tag="ECOK1_0406"
                     /note="Proteins similar to Escherichia coli YajQ; Region:
                     YajQ_like; cd11740"
                     /db_xref="CDD:213038"
     gene            complement(448705..450069)
                     /locus_tag="ECOK1_0407"
                     /db_xref="GeneID:12688975"
     CDS             complement(448705..450069)
                     /locus_tag="ECOK1_0407"
                     /note="identified by match to protein family HMM PF07690"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator family transporter"
                     /protein_id="YP_006099648.1"
                     /db_xref="GI:386598142"
                     /db_xref="GeneID:12688975"
                     /translation="MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
                     ASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIW
                     GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITH
                     KLGLHVLFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLN
                     FGIMCLHILLMSTFVALPGQLADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRK
                     MKQVFVFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAG
                     YKGTAMGVYSTSQFLGVAIGGSLGGWIDGMFDGQGVFLAGAMLAAVWLAVASTMKEPP
                     YVSSLRIEIPANIAANEALKVRLLETEGIKEVLIAEEEHSAYVKIDSKVTNRFEVEQA
                     IRQA"
     misc_feature    complement(448915..450030)
                     /locus_tag="ECOK1_0407"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(449005..450021)
                     /locus_tag="ECOK1_0407"
                     /note="Major Facilitator Superfamily; Region: MFS_1;
                     pfam07690"
                     /db_xref="CDD:254360"
     misc_feature    complement(order(449017..449019,449026..449031,
                     449038..449043,449050..449055,449086..449088,
                     449095..449100,449110..449112,449119..449124,
                     449131..449133,449275..449277,449287..449289,
                     449296..449298,449308..449310,449320..449322,
                     449362..449364,449371..449376,449383..449388,
                     449395..449397,449626..449628,449644..449649,
                     449656..449661,449695..449697,449704..449709,
                     449716..449721,449728..449733,449863..449868,
                     449872..449877,449887..449889,449896..449901,
                     449908..449910,449962..449967,449971..449979,
                     449986..449988))
                     /locus_tag="ECOK1_0407"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(450218..451108)
                     /gene="cyoE"
                     /locus_tag="ECOK1_0408"
                     /db_xref="GeneID:12688976"
     CDS             complement(450218..451108)
                     /gene="cyoE"
                     /locus_tag="ECOK1_0408"
                     /EC_number="2.5.1.-"
                     /note="identified by match to protein family HMM PF01040;
                     match to protein family HMM TIGR01473"
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="YP_006099649.1"
                     /db_xref="GI:386598143"
                     /db_xref="GeneID:12688976"
                     /translation="MIFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
                     GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLW
                     FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDS
                     GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAV
                     ATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALS
                     VMMSVDFMVPDSHTLLAAVW"
     misc_feature    complement(450275..451090)
                     /gene="cyoE"
                     /locus_tag="ECOK1_0408"
                     /note="Protoheme IX farnesyltransferase; Region:
                     PT_UbiA_Cox10; cd13957"
                     /db_xref="CDD:260120"
     misc_feature    complement(order(450548..450550,450914..450916,
                     450926..450928))
                     /gene="cyoE"
                     /locus_tag="ECOK1_0408"
                     /note="putative active site [active]"
                     /db_xref="CDD:260120"
     gene            complement(451120..451449)
                     /gene="cyoD"
                     /locus_tag="ECOK1_0409"
                     /db_xref="GeneID:12688977"
     CDS             complement(451120..451449)
                     /gene="cyoD"
                     /locus_tag="ECOK1_0409"
                     /EC_number="1.10.3.-"
                     /note="identified by similarity to SP:P0ABJ6; match to
                     protein family HMM PF03626; match to protein family HMM
                     TIGR02847"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="YP_006099650.1"
                     /db_xref="GI:386598144"
                     /db_xref="GeneID:12688977"
                     /translation="MSHSNASSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPA
                     VILGTILAMAVVQILVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNL
                     NYNMMMH"
     misc_feature    complement(451123..451449)
                     /gene="cyoD"
                     /locus_tag="ECOK1_0409"
                     /note="cytochrome o ubiquinol oxidase subunit IV;
                     Provisional; Region: PRK10582"
                     /db_xref="CDD:182568"
     gene            complement(451449..452063)
                     /gene="cyoC"
                     /locus_tag="ECOK1_0410"
                     /db_xref="GeneID:12688978"
     CDS             complement(451449..452063)
                     /gene="cyoC"
                     /locus_tag="ECOK1_0410"
                     /EC_number="1.10.3.-"
                     /note="identified by similarity to SP:P0ABJ3; match to
                     protein family HMM PF00510; match to protein family HMM
                     TIGR02842"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="YP_006099651.1"
                     /db_xref="GI:386598145"
                     /db_xref="GeneID:12688978"
                     /translation="MATDTLTHATAHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILF
                     ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVVSWL
                     ALTWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
                     MVQIARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
     misc_feature    complement(451458..452015)
                     /gene="cyoC"
                     /locus_tag="ECOK1_0410"
                     /note="Ubiquinol oxidase subunit III subfamily. Ubiquinol
                     oxidase, the terminal oxidase in the respiratory chains of
                     aerobic bacteria, is a multi-chain transmembrane protein
                     located in the cell membrane.  It catalyzes the reduction
                     of O2 and simultaneously...; Region:
                     Ubiquinol_oxidase_III; cd02863"
                     /db_xref="CDD:239214"
     misc_feature    complement(order(451926..451928,451935..451940,
                     451947..451952,451971..451973,451980..451982,
                     451992..451997))
                     /gene="cyoC"
                     /locus_tag="ECOK1_0410"
                     /note="Subunit I/III interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239214"
     misc_feature    complement(order(451509..451511,451530..451532,
                     451815..451820,451830..451832,451839..451841,
                     451950..451952,451974..451976))
                     /gene="cyoC"
                     /locus_tag="ECOK1_0410"
                     /note="Subunit III/IV interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239214"
     gene            complement(452053..454044)
                     /gene="cyoB"
                     /locus_tag="ECOK1_0411"
                     /db_xref="GeneID:12688979"
     CDS             complement(452053..454044)
                     /gene="cyoB"
                     /locus_tag="ECOK1_0411"
                     /EC_number="1.10.3.-"
                     /note="identified by match to protein family HMM PF00115;
                     match to protein family HMM TIGR02843"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="YP_006099652.1"
                     /db_xref="GI:386598146"
                     /db_xref="GeneID:12688979"
                     /translation="MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYL
                     WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
                     FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL
                     GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP
                     GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
                     NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
                     FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFS
                     VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
                     TWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALG
                     ILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWE
                     MKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIIT
                     WIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN"
     misc_feature    complement(452221..453933)
                     /gene="cyoB"
                     /locus_tag="ECOK1_0411"
                     /note="Heme/copper-type cytochrome/quinol oxidases,
                     subunit 1 [Energy production and conversion]; Region:
                     CyoB; COG0843"
                     /db_xref="CDD:223913"
     misc_feature    complement(452389..453903)
                     /gene="cyoB"
                     /locus_tag="ECOK1_0411"
                     /note="Ubiquinol oxidase subunit I.  Ubiquinol oxidase,
                     the terminal oxidase in the respiratory chains of aerobic
                     bacteria, is a multi-chain transmembrane protein located
                     in the cell membrane.  It catalyzes the reduction of O2
                     and simultaneously pumps protons...; Region:
                     Ubiquinol_Oxidase_I; cd01662"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(453412..453414,453424..453426,
                     453442..453447,453610..453612,453619..453621,
                     453640..453642,453670..453672,453862..453864))
                     /gene="cyoB"
                     /locus_tag="ECOK1_0411"
                     /note="D-pathway; other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(453736..453744,453751..453753,
                     453808..453813,453820..453822,453832..453834))
                     /gene="cyoB"
                     /locus_tag="ECOK1_0411"
                     /note="Putative ubiquinol binding site [chemical binding];
                     other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(452530..452532,452644..452646,
                     452770..452772,452782..452784,453727..453729))
                     /gene="cyoB"
                     /locus_tag="ECOK1_0411"
                     /note="Low-spin heme (heme b) binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(452602..452604,452809..452814,
                     452824..452826,453214..453219,453232..453234))
                     /gene="cyoB"
                     /locus_tag="ECOK1_0411"
                     /note="Putative water exit pathway; other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(452788..452790,453043..453048,
                     453193..453195))
                     /gene="cyoB"
                     /locus_tag="ECOK1_0411"
                     /note="Binuclear center (heme o3/CuB) [ion binding]; other
                     site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(452959..452961,452968..452970,
                     453043..453048,453148..453150,453181..453183,
                     453193..453195))
                     /gene="cyoB"
                     /locus_tag="ECOK1_0411"
                     /note="K-pathway; other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(452599..452604,452809..452814,
                     453043..453045))
                     /gene="cyoB"
                     /locus_tag="ECOK1_0411"
                     /note="Putative proton exit pathway; other site"
                     /db_xref="CDD:238832"
     gene            complement(454066..455013)
                     /gene="cyoA"
                     /locus_tag="ECOK1_0412"
                     /db_xref="GeneID:12688980"
     CDS             complement(454066..455013)
                     /gene="cyoA"
                     /locus_tag="ECOK1_0412"
                     /EC_number="1.10.3.-"
                     /note="identified by similarity to SP:P0ABJ1; match to
                     protein family HMM PF00116; match to protein family HMM
                     PF06481; match to protein family HMM TIGR01433"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit II"
                     /protein_id="YP_006099653.1"
                     /db_xref="GI:386598147"
                     /db_xref="GeneID:12688980"
                     /translation="MRLRKYNKSLGWLSLFAGTVLLSGCNSALLDPKGQIGLEQRSLI
                     LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
                     LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIAAVNEIAFPANTP
                     VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
                     KFKAIATPDRAAFDQWVAKAKQSPNTMSDMATFEKLAAPSEYNQVEYFSNVKPDLFAD
                     VINKFMAHGKSMDMTQPEGEHSAHEGMEGMDMSHAESAH"
     misc_feature    complement(454069..455013)
                     /gene="cyoA"
                     /locus_tag="ECOK1_0412"
                     /note="cytochrome o ubiquinol oxidase subunit II;
                     Provisional; Region: PRK10525"
                     /db_xref="CDD:182518"
     misc_feature    complement(454339..454635)
                     /gene="cyoA"
                     /locus_tag="ECOK1_0412"
                     /note="The cupredoxin domain of Ubiquinol oxidase subunit
                     II; Region: CuRO_UO_II; cd04212"
                     /db_xref="CDD:259874"
     misc_feature    complement(454156..454299)
                     /gene="cyoA"
                     /locus_tag="ECOK1_0412"
                     /note="COX Aromatic Rich Motif; Region: COX_ARM;
                     pfam06481"
                     /db_xref="CDD:253759"
     gene            complement(455472..456947)
                     /gene="ampG"
                     /locus_tag="ECOK1_0413"
                     /db_xref="GeneID:12688981"
     CDS             complement(455472..456947)
                     /gene="ampG"
                     /locus_tag="ECOK1_0413"
                     /note="identified by match to protein family HMM PF07690;
                     match to protein family HMM TIGR00901"
                     /codon_start=1
                     /transl_table=11
                     /product="AmpG protein"
                     /protein_id="YP_006099654.1"
                     /db_xref="GI:386598148"
                     /db_xref="GeneID:12688981"
                     /translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
                     DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLE
                     PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
                     GLALWLADKWLGWQGMYWLMAALLIPCIIATLLAPEPTDTIPVPKTLEQAVVAPLRDF
                     FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
                     LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGT
                     SAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAA
                     VPGLILLLVCRQTLEYTRVNGNFISRTEYPAGYAFAMWTLAAGISLLAVWLLLLTMDA
                     LDLTHFSFLPALLEVGVLVALSGVVLGGLLDYLALRKTHLT"
     misc_feature    complement(455739..456905)
                     /gene="ampG"
                     /locus_tag="ECOK1_0413"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(455850..456899)
                     /gene="ampG"
                     /locus_tag="ECOK1_0413"
                     /note="Major Facilitator Superfamily; Region: MFS_1;
                     pfam07690"
                     /db_xref="CDD:254360"
     misc_feature    complement(order(455853..455855,455862..455867,
                     455874..455879,455886..455891,455922..455924,
                     455931..455936,455946..455948,455955..455960,
                     455967..455969,456120..456122,456132..456134,
                     456141..456143,456156..456158,456168..456170,
                     456210..456212,456219..456224,456231..456236,
                     456243..456245,456480..456482,456498..456503,
                     456510..456515,456549..456551,456558..456563,
                     456570..456575,456582..456587,456750..456755,
                     456759..456764,456777..456782,456789..456791,
                     456840..456845,456849..456857,456864..456866))
                     /gene="ampG"
                     /locus_tag="ECOK1_0413"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(456991..457569)
                     /locus_tag="ECOK1_0414"
                     /db_xref="GeneID:12688982"
     CDS             complement(456991..457569)
                     /locus_tag="ECOK1_0414"
                     /note="identified by match to protein family HMM PF03923"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipoprotein"
                     /protein_id="YP_006099655.1"
                     /db_xref="GI:386598149"
                     /db_xref="GeneID:12688982"
                     /translation="MFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQDPSLMGVT
                     VSINGADQRTDQALAKVTRDNQIVTLTASRDLRFLLQEVLEKQMTARGYMVGPNGPVN
                     LQIIVSQLYADVSQGNVRYNIATKADIAIIATAQNGNKMTKNYRASYNVEGAFQASNK
                     NIADAVNSVLTDTIADMSQDTSIHEFIKQNAR"
     misc_feature    complement(456994..457569)
                     /locus_tag="ECOK1_0414"
                     /note="hypothetical protein; Provisional; Region:
                     PRK11627"
                     /db_xref="CDD:183242"
     gene            complement(457631..457750)
                     /locus_tag="ECOK1_0415"
                     /db_xref="GeneID:12688983"
     CDS             complement(457631..457750)
                     /locus_tag="ECOK1_0415"
                     /note="identified by glimmer; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099656.1"
                     /db_xref="GI:386598150"
                     /db_xref="GeneID:12688983"
                     /translation="MKFTDLKIETQASHQRFFYQGRLFRQHDEFTCLTHFPSP"
     gene            457874..458191
                     /locus_tag="ECOK1_0416"
                     /db_xref="GeneID:12688984"
     CDS             457874..458191
                     /locus_tag="ECOK1_0416"
                     /note="identified by match to protein family HMM PF01722"
                     /codon_start=1
                     /transl_table=11
                     /product="protein BolA"
                     /protein_id="YP_006099657.1"
                     /db_xref="GI:386598151"
                     /db_xref="GeneID:12688984"
                     /translation="MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLV
                     SDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAG
                     SIA"
     misc_feature    457874..458188
                     /locus_tag="ECOK1_0416"
                     /note="transcriptional regulator BolA; Provisional;
                     Region: PRK11628"
                     /db_xref="CDD:183243"
     gene            458200..458388
                     /locus_tag="ECOK1_0417"
                     /db_xref="GeneID:12688985"
     CDS             458200..458388
                     /locus_tag="ECOK1_0417"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_006099658.1"
                     /db_xref="GI:386598152"
                     /db_xref="GeneID:12688985"
                     /translation="MQLSALFQYVAKDFMKNGLRAVLFCLDFALFAQHSDENRPGIVK
                     KYATARNNRSRLIKVMPL"
     gene            458535..459824
                     /gene="tig"
                     /locus_tag="ECOK1_0418"
                     /db_xref="GeneID:12688986"
     CDS             458535..459824
                     /gene="tig"
                     /locus_tag="ECOK1_0418"
                     /EC_number="5.2.1.8"
                     /note="identified by match to protein family HMM PF00254;
                     match to protein family HMM PF05697; match to protein
                     family HMM PF05698; match to protein family HMM TIGR00115"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="YP_006099659.1"
                     /db_xref="GI:386598153"
                     /db_xref="GeneID:12688986"
                     /translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
                     RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGED
                     FTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEA
                     EDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP
                     EEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMER
                     ELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPR
                     ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
                     ELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMN"
     misc_feature    458535..459821
                     /gene="tig"
                     /locus_tag="ECOK1_0418"
                     /note="trigger factor; Provisional; Region: tig; PRK01490"
                     /db_xref="CDD:234956"
     misc_feature    458535..458969
                     /gene="tig"
                     /locus_tag="ECOK1_0418"
                     /note="Bacterial trigger factor protein (TF); Region:
                     Trigger_N; pfam05697"
                     /db_xref="CDD:253331"
     misc_feature    458994..459248
                     /gene="tig"
                     /locus_tag="ECOK1_0418"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerase;
                     Region: FKBP_C; pfam00254"
                     /db_xref="CDD:249719"
     misc_feature    459318..459773
                     /gene="tig"
                     /locus_tag="ECOK1_0418"
                     /note="Bacterial trigger factor protein (TF) C-terminus;
                     Region: Trigger_C; pfam05698"
                     /db_xref="CDD:253332"
     gene            460079..460702
                     /gene="clpP"
                     /locus_tag="ECOK1_0419"
                     /db_xref="GeneID:12688987"
     CDS             460079..460702
                     /gene="clpP"
                     /locus_tag="ECOK1_0419"
                     /EC_number="3.4.21.92"
                     /note="identified by match to protein family HMM PF00574;
                     match to protein family HMM TIGR00493"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease, proteolytic subunit
                     ClpP"
                     /protein_id="YP_006099660.1"
                     /db_xref="GI:386598154"
                     /db_xref="GeneID:12688987"
                     /translation="MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
                     LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
                     TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
                     GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
     misc_feature    460172..460684
                     /gene="clpP"
                     /locus_tag="ECOK1_0419"
                     /note="Caseinolytic protease (ClpP) is an ATP-dependent,
                     highly conserved serine protease; Region: S14_ClpP_2;
                     cd07017"
                     /db_xref="CDD:132928"
     misc_feature    order(460208..460210,460214..460216,460241..460246,
                     460253..460258,460265..460267,460310..460312,
                     460331..460333,460343..460345,460352..460354,
                     460361..460366,460376..460378,460400..460402,
                     460466..460468,460472..460474,460490..460501,
                     460541..460543,460550..460552,460556..460558,
                     460562..460564,460631..460633,460637..460639)
                     /gene="clpP"
                     /locus_tag="ECOK1_0419"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:132928"
     misc_feature    order(460409..460411,460484..460486,460631..460633)
                     /gene="clpP"
                     /locus_tag="ECOK1_0419"
                     /note="active site residues [active]"
                     /db_xref="CDD:132928"
     gene            460828..462102
                     /gene="clpX"
                     /locus_tag="ECOK1_0420"
                     /db_xref="GeneID:12688988"
     CDS             460828..462102
                     /gene="clpX"
                     /locus_tag="ECOK1_0420"
                     /note="identified by match to protein family HMM PF00004;
                     match to protein family HMM PF06689; match to protein
                     family HMM PF07724; match to protein family HMM TIGR00382"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="YP_006099661.1"
                     /db_xref="GI:386598155"
                     /db_xref="GeneID:12688988"
                     /translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
                     NDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
                     DTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
                     IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKA
                     KSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALT
                     KQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMED
                     VEKVVIDESVIDGQSKPLLIYGKPEAQQASGE"
     misc_feature    460837..462078
                     /gene="clpX"
                     /locus_tag="ECOK1_0420"
                     /note="ATP-dependent protease ATP-binding subunit ClpX;
                     Provisional; Region: clpX; PRK05342"
                     /db_xref="CDD:235422"
     misc_feature    460864..460980
                     /gene="clpX"
                     /locus_tag="ECOK1_0420"
                     /note="ClpX C4-type zinc finger; Region: zf-C4_ClpX;
                     pfam06689"
                     /db_xref="CDD:253863"
     misc_feature    461062..>461412
                     /gene="clpX"
                     /locus_tag="ECOK1_0420"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    461182..461205
                     /gene="clpX"
                     /locus_tag="ECOK1_0420"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(461185..461208,461377..461379)
                     /gene="clpX"
                     /locus_tag="ECOK1_0420"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    461365..461382
                     /gene="clpX"
                     /locus_tag="ECOK1_0420"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    461776..462027
                     /gene="clpX"
                     /locus_tag="ECOK1_0420"
                     /note="C-terminal, D2-small domain, of ClpB protein;
                     Region: ClpB_D2-small; smart01086"
                     /db_xref="CDD:198154"
     gene            462290..464644
                     /gene="lon"
                     /locus_tag="ECOK1_0421"
                     /db_xref="GeneID:12688989"
     CDS             462290..464644
                     /gene="lon"
                     /locus_tag="ECOK1_0421"
                     /EC_number="3.4.21.53"
                     /note="identified by match to protein family HMM PF00004;
                     match to protein family HMM PF02190; match to protein
                     family HMM PF05362; match to protein family HMM PF07728;
                     match to protein family HMM TIGR00763"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease La"
                     /protein_id="YP_006099662.1"
                     /db_xref="GI:386598156"
                     /db_xref="GeneID:12688989"
                     /translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
                     DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
                     LSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
                     DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
                     KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
                     KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRI
                     LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
                     GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
                     AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
                     KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLK
                     HIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
                     TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
                     AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
                     KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
     misc_feature    462290..464641
                     /gene="lon"
                     /locus_tag="ECOK1_0421"
                     /note="DNA-binding ATP-dependent protease La; Provisional;
                     Region: PRK10787"
                     /db_xref="CDD:182730"
     misc_feature    462317..462895
                     /gene="lon"
                     /locus_tag="ECOK1_0421"
                     /note="Found in ATP-dependent protease La (LON); Region:
                     LON; cl19481"
                     /db_xref="CDD:271862"
     misc_feature    463262..463753
                     /gene="lon"
                     /locus_tag="ECOK1_0421"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    463355..463378
                     /gene="lon"
                     /locus_tag="ECOK1_0421"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(463358..463381,463556..463558,463706..463708)
                     /gene="lon"
                     /locus_tag="ECOK1_0421"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    463544..463561
                     /gene="lon"
                     /locus_tag="ECOK1_0421"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    463739..463741
                     /gene="lon"
                     /locus_tag="ECOK1_0421"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    463997..464602
                     /gene="lon"
                     /locus_tag="ECOK1_0421"
                     /note="Lon protease (S16) C-terminal proteolytic domain;
                     Region: Lon_C; pfam05362"
                     /db_xref="CDD:191262"
     STS             462510..463610
                     /gene="lon"
                     /locus_tag="ECOK1_0421"
                     /standard_name="D14S161"
                     /db_xref="UniSTS:148385"
     gene            464853..465125
                     /gene="hupB"
                     /locus_tag="ECOK1_0422"
                     /db_xref="GeneID:12688990"
     CDS             464853..465125
                     /gene="hupB"
                     /locus_tag="ECOK1_0422"
                     /note="identified by similarity to SP:P0ACF4; match to
                     protein family HMM PF00216"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-beta"
                     /protein_id="YP_006099663.1"
                     /db_xref="GI:386598157"
                     /db_xref="GeneID:12688990"
                     /translation="MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVAL
                     VGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
     misc_feature    464856..465113
                     /gene="hupB"
                     /locus_tag="ECOK1_0422"
                     /note="histone-like DNA-binding protein HU; Region: HU;
                     cd13831"
                     /db_xref="CDD:259853"
     misc_feature    order(464868..464870,464877..464882,464889..464891,
                     464916..464927,464931..464939,464943..464951,
                     464955..464960,464970..464984,464991..464993,
                     465075..465083,465087..465089,465093..465095,
                     465105..465110)
                     /gene="hupB"
                     /locus_tag="ECOK1_0422"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:259853"
     misc_feature    order(465009..465011,465015..465020,465024..465026,
                     465030..465041,465054..465059,465063..465065)
                     /gene="hupB"
                     /locus_tag="ECOK1_0422"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:259853"
     gene            465317..467188
                     /gene="ppiD"
                     /locus_tag="ECOK1_0423"
                     /db_xref="GeneID:12688991"
     CDS             465317..467188
                     /gene="ppiD"
                     /locus_tag="ECOK1_0423"
                     /EC_number="5.2.1.8"
                     /note="identified by similarity to SP:P0ADY1; match to
                     protein family HMM PF00639"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl isomerase"
                     /protein_id="YP_006099664.1"
                     /db_xref="GI:386598158"
                     /db_xref="GeneID:12688991"
                     /translation="MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAK
                     VNDQEISRGQFENAFNSERNRMQQQLGDQYSELAANEGYMKTLRQQVLNRLIDEALLD
                     QYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQL
                     TTQQLINGVAGTDFMLKGETDELAALVAQQRVVREATIDVNALAAKQPVTEQEIASYY
                     EQNKNNFMTPEQFRVSYIKLDAATMQQPVSDADIQSYYDQHQDQFTQPQRTRYSIIQT
                     KTEDEAKAVLDELNKGGDFAALAKEKSADIISARNGGDMGWLEDATIPDELKNAGLKE
                     KGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDIAAKVKHEKALDAYYALQQKVS
                     DAASNDTESLAGAEQAAGVKATQTGWFSKDNLPEELNFKPVADAIFNGGLVGENGAPG
                     INSDIITVDGDRAFVLRISEHKPEAVKPLADVQEQVKALVQHNKAEQQAKVDAEKLLV
                     DLKAGKGAEAMQAAGLKFGEPKTLSRSGRDPISQAAFALPLPAKDKPSYGMATDMQGN
                     VVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
     misc_feature    465317..467173
                     /gene="ppiD"
                     /locus_tag="ECOK1_0423"
                     /note="periplasmic folding chaperone; Provisional; Region:
                     PRK10788"
                     /db_xref="CDD:182731"
     misc_feature    465317..465814
                     /gene="ppiD"
                     /locus_tag="ECOK1_0423"
                     /note="SurA N-terminal domain; Region: SurA_N_3; cl21568"
                     /db_xref="CDD:271988"
     misc_feature    466055..466423
                     /gene="ppiD"
                     /locus_tag="ECOK1_0423"
                     /note="PPIC-type PPIASE domain; Region: Rotamase_2;
                     pfam13145"
                     /db_xref="CDD:257517"
     gene            467339..467710
                     /locus_tag="ECOK1_0424"
                     /db_xref="GeneID:12688992"
     CDS             467339..467710
                     /locus_tag="ECOK1_0424"
                     /note="identified by match to protein family HMM
                     TIGR00426"
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="YP_006099665.1"
                     /db_xref="GI:386598159"
                     /db_xref="GeneID:12688992"
                     /translation="MKHGIKALLITLSLACAGMSHSALAAASVAKPTTVETKAEAPAA
                     QSKAAVPAKASDEEGTRVSINNASAEELARAMNGVGLKKAQAIVSYREEYGPFKTVED
                     LKQVPGMGNSLVERNLAVLTL"
     misc_feature    467339..467707
                     /locus_tag="ECOK1_0424"
                     /note="DNA uptake protein and related DNA-binding proteins
                     [DNA replication, recombination, and repair]; Region:
                     ComEA; COG1555"
                     /db_xref="CDD:224472"
     misc_feature    467354..>467533
                     /locus_tag="ECOK1_0424"
                     /note="Bacterial cellulose synthase subunit; Region: BcsB;
                     cl15851"
                     /db_xref="CDD:265806"
     misc_feature    467501..467707
                     /locus_tag="ECOK1_0424"
                     /note="competence protein ComEA helix-hairpin-helix repeat
                     region; Region: TIGR00426"
                     /db_xref="CDD:129520"
     gene            467816..468214
                     /locus_tag="ECOK1_0425"
                     /db_xref="GeneID:12688993"
     CDS             467816..468214
                     /locus_tag="ECOK1_0425"
                     /note="identified by match to protein family HMM PF03061;
                     match to protein family HMM TIGR00051"
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="YP_006099666.1"
                     /db_xref="GI:386598160"
                     /db_xref="GeneID:12688993"
                     /translation="MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWHGLENSDSFHWM
                     TAHNIAFVVVNININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVADA
                     LITFVCIDLKTQKALALEGELREKLEQMVK"
     misc_feature    467822..468145
                     /locus_tag="ECOK1_0425"
                     /note="4-hydroxybenzoyl-C