LOCUS NC_017628 5108383 bp DNA circular BCT 24-DEC-2012
DEFINITION Escherichia coli IHE3034 chromosome, complete genome.
ACCESSION NC_017628
VERSION NC_017628.1 GI:386597751
DBLINK Project: 162007
BioProject: PRJNA162007
KEYWORDS .
SOURCE Escherichia coli IHE3034
ORGANISM Escherichia coli IHE3034
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
Enterobacteriaceae; Escherichia.
REFERENCE 1 (bases 1 to 5108383)
AUTHORS Moriel,D.G., Bertoldi,I., Spagnuolo,A., Marchi,S., Rosini,R.,
Nesta,B., Pastorello,I., Corea,V.A., Torricelli,G., Cartocci,E.,
Savino,S., Scarselli,M., Dobrindt,U., Hacker,J., Tettelin,H.,
Tallon,L.J., Sullivan,S., Wieler,L.H., Ewers,C., Pickard,D.,
Dougan,G., Fontana,M.R., Rappuoli,R., Pizza,M. and Serino,L.
TITLE Identification of protective and broadly conserved vaccine antigens
from the genome of extraintestinal pathogenic Escherichia coli
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 107 (20), 9072-9077 (2010)
PUBMED 20439758
REFERENCE 2 (bases 1 to 5108383)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (11-APR-2012) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 5108383)
AUTHORS Moriel,D.G., Serino,L., Pizza,M., Rappuoli,R., Dobrindt,U.,
Hacker,J., Kim,M., Vuong,H., Hostetler,J., Tallon,L.J.,
Nelson,W.C., Sullivan,S., Daugherty,S.C., Brinkac,L.M.,
Dodson,R.J., Durkin,A.S., Madupu,R., Harkins,D.M., Shrivastava,S.
and Tettelin,H.
TITLE Direct Submission
JOURNAL Submitted (26-FEB-2010) Novartis Vaccines, Via Florentina, 153100,
Siena, Italy
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to CP001969.
Source DNA and bacteria are available from Dr. Ulrich Dobrindt,
Institut fur Molekulare Infektionsbiologie Universitat, Wuerzburg
Josef-Schneider-Str. 2/Bau D15 97080 Wuerzburg Germany.
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..5108383
/organism="Escherichia coli IHE3034"
/mol_type="genomic DNA"
/strain="IHE3034"
/db_xref="taxon:714962"
/note="K1 strain"
gene 190..255
/gene="thrL"
/locus_tag="ECOK1_0001"
/db_xref="GeneID:12693254"
CDS 190..255
/gene="thrL"
/locus_tag="ECOK1_0001"
/note="identified by match to protein family HMM PF08254;
match to protein family HMM TIGR02077"
/codon_start=1
/transl_table=11
/product="thr operon leader peptide"
/protein_id="YP_006099258.1"
/db_xref="GI:386597752"
/db_xref="GeneID:12693254"
/translation="MKRISTTITTTITITTGNGAG"
gene 336..2798
/gene="thrA"
/locus_tag="ECOK1_0002"
/db_xref="GeneID:12693256"
CDS 336..2798
/gene="thrA"
/locus_tag="ECOK1_0002"
/EC_number="2.7.2.4"
/EC_number="1.1.1.3"
/note="identified by similarity to SP:P00561; match to
protein family HMM PF00696; match to protein family HMM
PF00742; match to protein family HMM PF01842; match to
protein family HMM PF03447; match to protein family HMM
TIGR00657"
/codon_start=1
/transl_table=11
/product="aspartokinase/homoserine dehydrogenase I"
/protein_id="YP_006099259.1"
/db_xref="GI:386597753"
/db_xref="GeneID:12693256"
/translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
NHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIK
HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHY
LESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
QIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAAR
VFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAV
TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKA
LLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
FLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSRRKFLYDTNVGAGLPVIENLQNLLN
AGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK
LLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEG
KVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
NDVTAAGVFADLLRTLSWKLGV"
misc_feature 336..2795
/gene="thrA"
/locus_tag="ECOK1_0002"
/note="bifunctional aspartokinase I/homoserine
dehydrogenase I; Provisional; Region: thrA; PRK09436"
/db_xref="CDD:181856"
misc_feature 336..1223
/gene="thrA"
/locus_tag="ECOK1_0002"
/note="AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK),
AK-HSDH; this CD includes the N-terminal catalytic domain
of aspartokinase (AK) of the bifunctional enzyme AK -
homoserine dehydrogenase (HSDH). These aspartokinases are
found in bacteria (E. coli...; Region: AAK_AK-HSDH;
cd04257"
/db_xref="CDD:239790"
misc_feature order(348..350,465..467,714..716,957..959,1092..1094,
1131..1133)
/gene="thrA"
/locus_tag="ECOK1_0002"
/note="putative catalytic residues [active]"
/db_xref="CDD:239790"
misc_feature order(348..350,354..362,1017..1022,1029..1034)
/gene="thrA"
/locus_tag="ECOK1_0002"
/note="putative nucleotide binding site [chemical
binding]; other site"
/db_xref="CDD:239790"
misc_feature order(447..452,465..467,714..716)
/gene="thrA"
/locus_tag="ECOK1_0002"
/note="putative aspartate binding site [chemical binding];
other site"
/db_xref="CDD:239790"
misc_feature 1278..1517
/gene="thrA"
/locus_tag="ECOK1_0002"
/note="ACT domains of the bifunctional enzyme
aspartokinase (AK) - homoserine dehydrogenase (HSDH);
Region: ACT_AKi-HSDH-ThrA-like_1; cd04921"
/db_xref="CDD:153193"
misc_feature order(1302..1310,1317..1322,1332..1334,1341..1346,
1365..1367,1371..1391,1395..1400,1404..1406,1410..1412)
/gene="thrA"
/locus_tag="ECOK1_0002"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:153193"
misc_feature 1386..1388
/gene="thrA"
/locus_tag="ECOK1_0002"
/note="putative threonine allosteric regulatory site;
other site"
/db_xref="CDD:153193"
misc_feature 1521..1718
/gene="thrA"
/locus_tag="ECOK1_0002"
/note="ACT domains of the bifunctional enzyme
aspartokinase (AK) - homoserine dehydrogenase (HSDH);
Region: ACT_AKi-HSDH-ThrA_2; cd04922"
/db_xref="CDD:153194"
misc_feature 1629..1631
/gene="thrA"
/locus_tag="ECOK1_0002"
/note="putative threonine allosteric regulatory site;
other site"
/db_xref="CDD:153194"
misc_feature 1770..2150
/gene="thrA"
/locus_tag="ECOK1_0002"
/note="Homoserine dehydrogenase, NAD binding domain;
Region: NAD_binding_3; pfam03447"
/db_xref="CDD:217564"
misc_feature 2175..2765
/gene="thrA"
/locus_tag="ECOK1_0002"
/note="Homoserine dehydrogenase; Region: Homoserine_dh;
pfam00742"
/db_xref="CDD:216092"
gene 2800..3732
/gene="thrB"
/locus_tag="ECOK1_0003"
/db_xref="GeneID:12693365"
CDS 2800..3732
/gene="thrB"
/locus_tag="ECOK1_0003"
/EC_number="2.7.1.39"
/note="identified by similarity to SP:P00547; match to
protein family HMM PF00288; match to protein family HMM
PF08544; match to protein family HMM TIGR00191"
/codon_start=1
/transl_table=11
/product="homoserine kinase"
/protein_id="YP_006099260.1"
/db_xref="GI:386597754"
/db_xref="GeneID:12693365"
/translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETF
SLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACS
VVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
PELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTA
QRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN"
misc_feature 2803..3723
/gene="thrB"
/locus_tag="ECOK1_0003"
/note="homoserine kinase; Region: thrB; TIGR00191"
/db_xref="CDD:129295"
misc_feature <2809..3159
/gene="thrB"
/locus_tag="ECOK1_0003"
/note="Protein of unknown function; Region: YhfT;
pfam10797"
/db_xref="CDD:220877"
misc_feature 3049..3249
/gene="thrB"
/locus_tag="ECOK1_0003"
/note="GHMP kinases N terminal domain; Region:
GHMP_kinases_N; pfam00288"
/db_xref="CDD:215839"
gene 3733..5019
/gene="thrC"
/locus_tag="ECOK1_0004"
/db_xref="GeneID:12693457"
CDS 3733..5019
/gene="thrC"
/locus_tag="ECOK1_0004"
/EC_number="4.2.3.1"
/note="identified by similarity to SP:P00934; match to
protein family HMM PF00291; match to protein family HMM
TIGR00260"
/codon_start=1
/transl_table=11
/product="threonine synthase"
/protein_id="YP_006099261.1"
/db_xref="GI:386597755"
/db_xref="GeneID:12693457"
/translation="MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEID
EMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP
TLAFKDFGGRFMAQILTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISR
LLAQICYYFEAVAQLPQEARNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
DTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE
TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGE
TLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ"
misc_feature 3733..5013
/gene="thrC"
/locus_tag="ECOK1_0004"
/note="Threonine synthase [Amino acid transport and
metabolism]; Region: ThrC; COG0498"
/db_xref="CDD:223572"
misc_feature 3736..5001
/gene="thrC"
/locus_tag="ECOK1_0004"
/note="Threonine synthase catalyzes the final step of
threonine biosynthesis. The conversion of
O-phosphohomoserine into threonine and inorganic phosphate
is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD
includes members from higher plants; Region: Thr-synth_2;
cd01560"
/db_xref="CDD:107203"
misc_feature order(4051..4053,4474..4479,4858..4860)
/gene="thrC"
/locus_tag="ECOK1_0004"
/note="pyridoxal 5'-phosphate binding site [chemical
binding]; other site"
/db_xref="CDD:107203"
misc_feature 4051..4053
/gene="thrC"
/locus_tag="ECOK1_0004"
/note="catalytic residue [active]"
/db_xref="CDD:107203"
gene complement(5309..5557)
/locus_tag="ECOK1_0005"
/db_xref="GeneID:12693459"
CDS complement(5309..5557)
/locus_tag="ECOK1_0005"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099262.1"
/db_xref="GI:386597756"
/db_xref="GeneID:12693459"
/translation="MPDGNPALIFSDDVCPAPDDDRHDDHCACYGAAMAAVHMGASDC
LAIHNVVSTSRGRASDRHPSNSHDYHDRLSVILLTGLA"
gene complement(5569..6345)
/locus_tag="ECOK1_0006"
/db_xref="GeneID:12693461"
CDS complement(5569..6345)
/locus_tag="ECOK1_0006"
/note="identified by similarity to SP:Q8FLD3; match to
protein family HMM PF03883"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099263.1"
/db_xref="GI:386597757"
/db_xref="GeneID:12693461"
/translation="MLILISPAKTLDYQSPLTTTRYTLPELLDNAQQLIHEARKLTPP
QISSLMRISDKLAGINAARFHDWQPNFTPENARQAILAFKGDVYTGLQAETFSEDDFD
FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRF
IIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR"
misc_feature complement(5575..6345)
/locus_tag="ECOK1_0006"
/note="hypothetical protein; Validated; Region: PRK02101"
/db_xref="CDD:234999"
gene complement(6415..7845)
/gene="agcS"
/locus_tag="ECOK1_0007"
/db_xref="GeneID:12693489"
CDS complement(6415..7845)
/gene="agcS"
/locus_tag="ECOK1_0007"
/note="identified by match to protein family HMM PF01235;
match to protein family HMM TIGR00835"
/codon_start=1
/transl_table=11
/product="amino acid carrier protein"
/protein_id="YP_006099264.1"
/db_xref="GI:386597758"
/db_xref="GeneID:12693489"
/translation="MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFG
KSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIG
MATSFAECSLAQLYKERDANGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYAIIFSG
VQANAVARALSFSFDFPPLVTGIILAVFALLAITRGLHGVARLMQGFVPLMAIIWVLT
CLVICVMNIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMG
STPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQ
LIQKAMRVLMGSWGAEFVTLVVILFAFSSIVTNYIYAENNLFFLRLNNPKAIWCLRIC
TFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVR
PVFDPLRYPEIGRQLSPDAWDDVSQE"
misc_feature complement(6499..7845)
/gene="agcS"
/locus_tag="ECOK1_0007"
/note="Na+/alanine symporter [Amino acid transport and
metabolism]; Region: AlsT; COG1115"
/db_xref="CDD:31312"
misc_feature complement(6472..7704)
/gene="agcS"
/locus_tag="ECOK1_0007"
/note="Sodium:alanine symporter family; Region:
Na_Ala_symp; pfam01235"
/db_xref="CDD:110251"
gene 8124..9077
/gene="tal"
/locus_tag="ECOK1_0008"
/db_xref="GeneID:12693491"
CDS 8124..9077
/gene="tal"
/locus_tag="ECOK1_0008"
/EC_number="2.2.1.2"
/note="identified by match to protein family HMM PF00923;
match to protein family HMM TIGR00874"
/codon_start=1
/transl_table=11
/product="transaldolase"
/protein_id="YP_006099265.1"
/db_xref="GI:386597759"
/db_xref="GeneID:12693491"
/translation="MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
IPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLS
YDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
FAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGY
ETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARI
TESEFLWQHNQDPMAVDKLAEGIRKFAVDQEKLEKMIGDLL"
misc_feature 8124..9074
/gene="tal"
/locus_tag="ECOK1_0008"
/note="transaldolase-like protein; Provisional; Region:
PTZ00411"
/db_xref="CDD:240406"
misc_feature 8133..9062
/gene="tal"
/locus_tag="ECOK1_0008"
/note="Transaldolases including both TalA and TalB;
Region: Transaldolase_TalAB; cd00957"
/db_xref="CDD:188644"
misc_feature order(8172..8174,8220..8222,8226..8231,8403..8405,
8409..8411,8517..8519,8583..8585,8589..8591,8649..8651,
8664..8666)
/gene="tal"
/locus_tag="ECOK1_0008"
/note="active site"
/db_xref="CDD:188644"
misc_feature order(8433..8435,8958..8960,8967..8969,8979..8984,
9000..9002,9009..9011,9021..9023)
/gene="tal"
/locus_tag="ECOK1_0008"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:188644"
misc_feature 8517..8519
/gene="tal"
/locus_tag="ECOK1_0008"
/note="catalytic residue [active]"
/db_xref="CDD:188644"
gene 9192..9779
/gene="mog"
/locus_tag="ECOK1_0009"
/db_xref="GeneID:12693252"
CDS 9192..9779
/gene="mog"
/locus_tag="ECOK1_0009"
/note="identified by similarity to SP:P0AF03; match to
protein family HMM PF00994; match to protein family HMM
TIGR00177"
/codon_start=1
/transl_table=11
/product="molybdopterin biosynthesis protein Mog"
/protein_id="YP_006099266.1"
/db_xref="GI:386597760"
/db_xref="GeneID:12693252"
/translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET
RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQ
MRQISLHFVLTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFA
SVPYCIQLLEGPYVETAPEVVAAFRPKSARREVSE"
misc_feature 9201..9659
/gene="mog"
/locus_tag="ECOK1_0009"
/note="MogA_MoaB family. Members of this family are
involved in biosynthesis of the molybdenum cofactor (MoCF)
an essential cofactor of a diverse group of redox enzymes.
MoCF biosynthesis is an evolutionarily conserved pathway
present in eubacteria, archaea; Region: MogA_MoaB;
cd00886"
/db_xref="CDD:58167"
misc_feature order(9414..9422,9510..9512,9588..9593,9603..9605,
9612..9614)
/gene="mog"
/locus_tag="ECOK1_0009"
/note="MPT binding site; other site"
/db_xref="CDD:58167"
misc_feature order(9420..9422,9426..9431,9435..9437,9447..9449,
9471..9479,9492..9494,9501..9506,9534..9536,9543..9545)
/gene="mog"
/locus_tag="ECOK1_0009"
/note="trimer interface [polypeptide binding]; other site"
/db_xref="CDD:58167"
gene complement(9984..10550)
/locus_tag="ECOK1_0010"
/db_xref="GeneID:12688578"
CDS complement(9984..10550)
/locus_tag="ECOK1_0010"
/note="identified by match to protein family HMM PF01184"
/codon_start=1
/transl_table=11
/product="membrane protein, GPR1/FUN34/yaaH family"
/protein_id="YP_006099267.1"
/db_xref="GI:386597761"
/db_xref="GeneID:12688578"
/translation="MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIF
YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVY
LGLWGIFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
GASAIYLAMGEVLNEQFGRTVLPIGESH"
misc_feature complement(9987..10550)
/locus_tag="ECOK1_0010"
/note="hypothetical protein; Provisional; Region:
PRK10659"
/db_xref="CDD:182625"
gene complement(10699..11412)
/locus_tag="ECOK1_0011"
/db_xref="GeneID:12688579"
CDS complement(10699..11412)
/locus_tag="ECOK1_0011"
/note="identified by match to protein family HMM PF03667"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099268.1"
/db_xref="GI:386597762"
/db_xref="GeneID:12688579"
/translation="MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLM
RNELFKSMEGHPERHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKL
KADKEMSTFEIEQQLLEQFLRNTWKKMDEEHKQEFLHAVDARVNELEELLPLLMKDKL
LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSAYRVT
IPAVLQIACLRRMVSATQV"
misc_feature complement(10702..11412)
/locus_tag="ECOK1_0011"
/note="hypothetical protein; Provisional; Region:
PRK10236"
/db_xref="CDD:182323"
misc_feature complement(11296..11400)
/locus_tag="ECOK1_0011"
/note="Domain of unknown function (DUF3944); Region:
DUF3944; pfam13099"
/db_xref="CDD:205280"
misc_feature complement(10702..11298)
/locus_tag="ECOK1_0011"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG4735"
/db_xref="CDD:227078"
gene complement(11438..11842)
/locus_tag="ECOK1_0012"
/db_xref="GeneID:12688580"
CDS complement(11438..11842)
/locus_tag="ECOK1_0012"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099269.1"
/db_xref="GI:386597763"
/db_xref="GeneID:12688580"
/translation="MKSVITISASLAISLMLCCTAQANDHKILGVIAMPRNETNDLAL
KLPVCRIVKRIQLSADHGDLQLSGASIYFKATRSASQTLNIPSEIKEEQTTDWININS
DNDNKRCVSKITFSGHTVNSSDMATLKIIGDD"
misc_feature complement(11441..11842)
/locus_tag="ECOK1_0012"
/note="hypothetical protein; Provisional; Region:
PRK10154"
/db_xref="CDD:182272"
gene 12214..14130
/gene="dnaK"
/locus_tag="ECOK1_0013"
/db_xref="GeneID:12688581"
CDS 12214..14130
/gene="dnaK"
/locus_tag="ECOK1_0013"
/note="identified by match to protein family HMM PF00012;
match to protein family HMM TIGR02350"
/codon_start=1
/transl_table=11
/product="chaperone protein DnaK"
/protein_id="YP_006099270.1"
/db_xref="GI:386597764"
/db_xref="GeneID:12688581"
/translation="MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQ
DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAW
VEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
LATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
DDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
DVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAAD
NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
EDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
SALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDD
DVVDAEFEEVKDKK"
misc_feature 12214..14013
/gene="dnaK"
/locus_tag="ECOK1_0013"
/note="molecular chaperone DnaK; Provisional; Region:
dnaK; PRK00290"
/db_xref="CDD:234715"
misc_feature 12214..13320
/gene="dnaK"
/locus_tag="ECOK1_0013"
/note="Nucleotide-binding domain of human HSPA9,
Escherichia coli DnaK, and similar proteins; Region:
HSPA9-like_NBD; cd11733"
/db_xref="CDD:212683"
misc_feature order(12241..12252,12421..12423,12724..12726,12799..12804,
12808..12810,12898..12900,13012..13014,13021..13023,
13033..13035,13234..13242,13246..13248)
/gene="dnaK"
/locus_tag="ECOK1_0013"
/note="nucleotide binding site [chemical binding]; other
site"
/db_xref="CDD:212683"
misc_feature order(12295..12297,12304..12306,12358..12360,12370..12372,
12379..12384,12388..12393,12598..12609,12982..12984,
12991..12996,13003..13005,13057..13059,13063..13068)
/gene="dnaK"
/locus_tag="ECOK1_0013"
/note="NEF interaction site [polypeptide binding]; other
site"
/db_xref="CDD:212683"
misc_feature order(12655..12660,12664..12669,12712..12717,12721..12723,
12859..12870)
/gene="dnaK"
/locus_tag="ECOK1_0013"
/note="SBD interface [polypeptide binding]; other site"
/db_xref="CDD:212683"
gene 14219..15349
/gene="dnaJ"
/locus_tag="ECOK1_0014"
/db_xref="GeneID:12688582"
CDS 14219..15349
/gene="dnaJ"
/locus_tag="ECOK1_0014"
/note="identified by match to protein family HMM PF00226;
match to protein family HMM PF00684; match to protein
family HMM PF01556; match to protein family HMM TIGR02349"
/codon_start=1
/transl_table=11
/product="chaperone protein DnaJ"
/protein_id="YP_006099271.1"
/db_xref="GI:386597765"
/db_xref="GeneID:12688582"
/translation="MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAE
AKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIF
GGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPA
GVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAAL
GGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLN
EKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR"
misc_feature 14219..15334
/gene="dnaJ"
/locus_tag="ECOK1_0014"
/note="chaperone protein DnaJ; Provisional; Region:
PRK10767"
/db_xref="CDD:236757"
misc_feature 14231..14395
/gene="dnaJ"
/locus_tag="ECOK1_0014"
/note="DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock
protein 40) proteins are highly conserved and play crucial
roles in protein translation, folding, unfolding,
translocation, and degradation. They act primarily by
stimulating the ATPase activity of Hsp70s; Region: DnaJ;
cd06257"
/db_xref="CDD:99751"
misc_feature order(14315..14323,14348..14350,14357..14362,14369..14374)
/gene="dnaJ"
/locus_tag="ECOK1_0014"
/note="HSP70 interaction site [polypeptide binding]; other
site"
/db_xref="CDD:99751"
misc_feature 14564..>14647
/gene="dnaJ"
/locus_tag="ECOK1_0014"
/note="C-terminal substrate binding domain of DnaJ and
HSP40; Region: DnaJ_C; cl03262"
/db_xref="CDD:243362"
misc_feature order(14573..14575,14618..14635)
/gene="dnaJ"
/locus_tag="ECOK1_0014"
/note="substrate binding site [polypeptide binding]; other
site"
/db_xref="CDD:199909"
misc_feature 14648..14830
/gene="dnaJ"
/locus_tag="ECOK1_0014"
/note="Zinc finger domain of DnaJ and HSP40; Region:
DnaJ_zf; cd10719"
/db_xref="CDD:199908"
misc_feature order(14648..14650,14657..14659,14699..14701,14708..14710,
14765..14767,14774..14776,14807..14809,14816..14818)
/gene="dnaJ"
/locus_tag="ECOK1_0014"
/note="Zn binding sites [ion binding]; other site"
/db_xref="CDD:199908"
misc_feature 14831..15217
/gene="dnaJ"
/locus_tag="ECOK1_0014"
/note="C-terminal substrate binding domain of DnaJ and
HSP40; Region: DnaJ_C; cd10747"
/db_xref="CDD:199909"
misc_feature order(15029..15034,15041..15046,15104..15115,15203..15217)
/gene="dnaJ"
/locus_tag="ECOK1_0014"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:199909"
gene 16218..16979
/locus_tag="ECOK1_0015"
/db_xref="GeneID:12688583"
CDS 16218..16979
/locus_tag="ECOK1_0015"
/note="identified by similarity to GB:AAV76071.1; match to
protein family HMM PF07135"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099272.1"
/db_xref="GI:386597766"
/db_xref="GeneID:12688583"
/translation="MSAKRRLLIACALTTIFYHLPAYSSLEYKGSFGSINAGYADWNS
GFINTHRGEVWKVTADFGVNFKEAEFYSFYESNVLNHAVAGRNHTVSAMTHVRLFDSN
MTFFGKIYGQWDNSWGDDLDMFYGLGYLGWNGSWGFFKPYIGLHNQSGDYVSAKYGQT
NGWNGYVVGWTAVLPFTLFDEKFVLSNWNEIELDRNDAYAEQQFGRNGLNGGLTVAWK
FYPRWKASVTWRYFDNKLGYDGFGDQMIYMLGYDF"
misc_feature 16326..16976
/locus_tag="ECOK1_0015"
/note="Nucleoside-specific channel-forming protein, Tsx;
Region: Channel_Tsx; pfam03502"
/db_xref="CDD:190665"
gene 16999..18492
/locus_tag="ECOK1_0016"
/db_xref="GeneID:12688584"
CDS 16999..18492
/locus_tag="ECOK1_0016"
/EC_number="3.1.6.-"
/note="identified by match to protein family HMM PF00884"
/codon_start=1
/transl_table=11
/product="sulfatase"
/protein_id="YP_006099273.1"
/db_xref="GI:386597767"
/db_xref="GeneID:12688584"
/translation="MQKTLMASLIGLAVCTGNAFNPVVAAETKQPNLVIIMADDLGYG
DLATYGHQIVKTPNIDRLAQEGVKFTDYYAPAPLSSPSRAGLLTGRMPFRTGIRSWIP
TGKDVALGRNELTIANLLKAQGYDTAMMGKLHLNAGGDRTDQPQAKDMGFDYSLVNTA
GFVTDATLDNAKERPRYGMVYPTGWLRNGQPTPRADKMSGEYVSSEVVNWLDNKKDSK
PFFLYVAFTEVHSPLASPKKYLDMYSQYMSAYQKQHPDLFYGDWADKPWRGVGEYYAN
ISYLDAQVGKVLDKIKAMGEEDNTIVIFTSDNGPVTREARKVYELNLAGETDGLRGRK
DNLWEGGIRVPAIIKYGKHLPQGMVSDTPVYGLDWMPTLAKMMNFKLPTDRTFDGESL
VPVLEQKALKREKPLIFGIDMPFQDDPTDEWAIRDGDWKMIIDRNNKPKYLYNLKSDR
YETLNLIGKKPDIEKQMYGKFLKYKTDIDNDSLMKARGDKPEAVTWG"
misc_feature 17077..18366
/locus_tag="ECOK1_0016"
/note="Arylsulfatase A and related enzymes [Inorganic ion
transport and metabolism]; Region: AslA; COG3119"
/db_xref="CDD:32933"
misc_feature 17089..18201
/locus_tag="ECOK1_0016"
/note="Sulfatase; Region: Sulfatase; pfam00884"
/db_xref="CDD:201490"
gene 18621..19880
/locus_tag="ECOK1_0017"
/db_xref="GeneID:12688585"
CDS 18621..19880
/locus_tag="ECOK1_0017"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099274.1"
/db_xref="GI:386597768"
/db_xref="GeneID:12688585"
/translation="MFTNVNVDCCKTPGCKNLGLLNSQDYVAQGKNILCRECGYLFPV
ISEQSLNIYRNIVNHSWRGLICQCSTCGGTSLKKYGYSAQGQRRMYCHHCEKTFITLE
HVITTPRGALLALMIEQGEALADIRKSLLLNSTGLSRELLKLAREANYKESRQCFPAS
DITLSTRAFRVKYNGSNNSLYALVTAEEQSGRVVAISTNYSPSAVEQHYQYTSNYEER
MSPGTLAHHVQRKELLTMRRDTLFDIDYGPAVLHQNDPGMLVKPVLPAYRHFELVRIL
TDEHSNNVQHYLDHECFILGGCLMANLQHIPQGRCHISFVKERGVAPATIDFPPRLFL
SGGVRNNVWRAFSNRNYSMAVCNLTGSKKVREMRHATLNSATRFIHFVENHPFLISLN
RMSPANVVSTLDILKHLWNKKLEHGTI"
gene 20115..21281
/gene="nhaA"
/locus_tag="ECOK1_0018"
/db_xref="GeneID:12688586"
CDS 20115..21281
/gene="nhaA"
/locus_tag="ECOK1_0018"
/note="identified by similarity to SP:P13738; match to
protein family HMM PF06965; match to protein family HMM
TIGR00773"
/codon_start=1
/transl_table=11
/product="Na+/H+ antiporter NhaA"
/protein_id="YP_006099275.1"
/db_xref="GI:386597769"
/db_xref="GeneID:12688586"
/translation="MKHLHRFFSSDASGGIILIIAAVLAMIMANSGATSGWYHDFLET
PVQLRVGTLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAI
GGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLVVLNLCGVRRTGVYILVGVVLWTA
VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
QGVTLEGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGIL
CGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV"
misc_feature 20115..21278
/gene="nhaA"
/locus_tag="ECOK1_0018"
/note="pH-dependent sodium/proton antiporter; Reviewed;
Region: nhaA; PRK09561"
/db_xref="CDD:181955"
gene 21341..22246
/gene="nhaR"
/locus_tag="ECOK1_0019"
/db_xref="GeneID:12688587"
CDS 21341..22246
/gene="nhaR"
/locus_tag="ECOK1_0019"
/note="identified by similarity to SP:P0A9G2; match to
protein family HMM PF00126; match to protein family HMM
PF03466"
/codon_start=1
/transl_table=11
/product="transcriptional activator protein NhaR"
/protein_id="YP_006099276.1"
/db_xref="GI:386597770"
/db_xref="GeneID:12688587"
/translation="MSMSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRAL
EERLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVA
DALSKRLVSSVLDAAVVEDEQIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQE
GLFSMKIGECGVSFWCTNPLPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNV
EILGEFDDAALMKAFGATHNAIFVAPSLYANDFYNDDSVVEIGRVENVMEEYHAIFAE
RMIQHPAVQRICNTDYSALFTPASK"
misc_feature 21347..22234
/gene="nhaR"
/locus_tag="ECOK1_0019"
/note="transcriptional activator NhaR; Provisional;
Region: nhaR; PRK11062"
/db_xref="CDD:182938"
misc_feature 21365..21541
/gene="nhaR"
/locus_tag="ECOK1_0019"
/note="Bacterial regulatory helix-turn-helix protein, lysR
family; Region: HTH_1; pfam00126"
/db_xref="CDD:201021"
misc_feature 21626..22228
/gene="nhaR"
/locus_tag="ECOK1_0019"
/note="The C-terminal substrate binding domain of
LysR-type transcriptional activator of the nhaA gene,
encoding Na+/H+ antiporter, contains the type 2
periplasmic binding fold; Region: PBP2_NhaR; cd08429"
/db_xref="CDD:176120"
misc_feature order(21671..21676,21680..21685,21692..21694,21704..21706,
21710..21730,22001..22018,22034..22039,22043..22048)
/gene="nhaR"
/locus_tag="ECOK1_0019"
/note="putative dimerization interface [polypeptide
binding]; other site"
/db_xref="CDD:176120"
gene complement(22342..22605)
/gene="rpsT"
/locus_tag="ECOK1_0020"
/db_xref="GeneID:12688588"
CDS complement(22342..22605)
/gene="rpsT"
/locus_tag="ECOK1_0020"
/note="identified by match to protein family HMM PF01649;
match to protein family HMM TIGR00029"
/codon_start=1
/transl_table=11
/product="30S ribosomal protein S20"
/protein_id="YP_006099277.1"
/db_xref="GI:386597771"
/db_xref="GeneID:12688588"
/translation="MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
AAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
misc_feature complement(22345..22605)
/gene="rpsT"
/locus_tag="ECOK1_0020"
/note="30S ribosomal protein S20; Reviewed; Region: rpsT;
PRK00239"
/db_xref="CDD:178943"
gene 22934..23875
/gene="ribF"
/locus_tag="ECOK1_0021"
/db_xref="GeneID:12688589"
CDS 22934..23875
/gene="ribF"
/locus_tag="ECOK1_0021"
/EC_number="2.7.1.26"
/EC_number="2.7.7.2"
/note="identified by match to protein family HMM PF01687;
match to protein family HMM PF06574; match to protein
family HMM TIGR00083"
/codon_start=1
/transl_table=11
/product="riboflavin biosynthesis protein RibF"
/protein_id="YP_006099278.1"
/db_xref="GI:386597772"
/db_xref="GeneID:12688589"
/translation="MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGR
KRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAAL
TAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQV
SPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVL
RKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA"
misc_feature 22937..23860
/gene="ribF"
/locus_tag="ECOK1_0021"
/note="bifunctional riboflavin kinase/FMN
adenylyltransferase; Reviewed; Region: PRK05627"
/db_xref="CDD:235536"
misc_feature 22985..23527
/gene="ribF"
/locus_tag="ECOK1_0021"
/note="FAD synthetase, N-terminal domain of the
bifunctional enzyme; Region: FAD_synthetase_N; cd02064"
/db_xref="CDD:185679"
misc_feature order(23000..23011,23018..23020,23027..23029,23309..23311,
23399..23401,23423..23431)
/gene="ribF"
/locus_tag="ECOK1_0021"
/note="active site"
/db_xref="CDD:185679"
misc_feature 23483..23854
/gene="ribF"
/locus_tag="ECOK1_0021"
/note="Riboflavin kinase; Region: Flavokinase; smart00904"
/db_xref="CDD:214901"
gene 23918..26734
/gene="ileS"
/locus_tag="ECOK1_0022"
/db_xref="GeneID:12688590"
CDS 23918..26734
/gene="ileS"
/locus_tag="ECOK1_0022"
/EC_number="6.1.1.5"
/note="identified by match to protein family HMM PF00133;
match to protein family HMM PF06827; match to protein
family HMM PF08264; match to protein family HMM PF09334;
match to protein family HMM TIGR00392"
/codon_start=1
/transl_table=11
/product="isoleucyl-tRNA synthetase"
/protein_id="YP_006099279.1"
/db_xref="GI:386597773"
/db_xref="GeneID:12688590"
/translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIIKSKGLSGYDSPYVPGWDCHGLPI
ELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFLAVD
QDALKTKFGVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD
LVESVMQRIGVSDYTILGTVKGAELELLRFTHPFMDFDVPAILGDHVTLDAGTGAVHT
APGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVIALLQEKGA
LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQA
RIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAW
WDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQH
RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADI
LRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMV
VLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKA
DSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGL
ADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELAAKLTALG
DELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKV
AEHAEICGRCVSNVAGDGEKRKFA"
misc_feature 23918..26707
/gene="ileS"
/locus_tag="ECOK1_0022"
/note="isoleucyl-tRNA synthetase; Reviewed; Region: ileS;
PRK05743"
/db_xref="CDD:180231"
misc_feature 24062..>24478
/gene="ileS"
/locus_tag="ECOK1_0022"
/note="catalytic core domain of isoleucyl-tRNA
synthetases; Region: IleRS_core; cd00818"
/db_xref="CDD:173909"
misc_feature 24110..24121
/gene="ileS"
/locus_tag="ECOK1_0022"
/note="HIGH motif; other site"
/db_xref="CDD:173909"
misc_feature <25151..25837
/gene="ileS"
/locus_tag="ECOK1_0022"
/note="catalytic core domain of isoleucyl-tRNA
synthetases; Region: IleRS_core; cd00818"
/db_xref="CDD:173909"
misc_feature order(25268..25270,25517..25519,25526..25528,25598..25612,
25616..25618,25622..25624,25691..25705,25715..25732,
25826..25828)
/gene="ileS"
/locus_tag="ECOK1_0022"
/note="active site"
/db_xref="CDD:173909"
misc_feature 25721..25735
/gene="ileS"
/locus_tag="ECOK1_0022"
/note="KMSKS motif; other site"
/db_xref="CDD:173909"
misc_feature 25835..26377
/gene="ileS"
/locus_tag="ECOK1_0022"
/note="Anticodon-binding domain of bacterial and
eukaryotic mitochondrial isoleucyl tRNA synthetases;
Region: Anticodon_Ia_Ile_BEm; cd07960"
/db_xref="CDD:153414"
misc_feature order(25844..25846,25856..25858,25865..25867,25877..25879,
25886..25888,25895..25900,26042..26044,26051..26056,
26063..26068,26075..26077,26090..26092,26102..26104,
26111..26113,26366..26368,26375..26377)
/gene="ileS"
/locus_tag="ECOK1_0022"
/note="tRNA binding surface [nucleotide binding]; other
site"
/db_xref="CDD:153414"
misc_feature order(25886..25888,25895..25897)
/gene="ileS"
/locus_tag="ECOK1_0022"
/note="anticodon binding site; other site"
/db_xref="CDD:153414"
misc_feature 26609..26698
/gene="ileS"
/locus_tag="ECOK1_0022"
/note="Zinc finger found in FPG and IleRS; Region:
zf-FPG_IleRS; pfam06827"
/db_xref="CDD:203527"
gene 26734..27228
/gene="lspA"
/locus_tag="ECOK1_0023"
/db_xref="GeneID:12688591"
CDS 26734..27228
/gene="lspA"
/locus_tag="ECOK1_0023"
/EC_number="3.4.23.36"
/note="identified by match to protein family HMM PF01252;
match to protein family HMM TIGR00077"
/codon_start=1
/transl_table=11
/product="signal peptidase II"
/protein_id="YP_006099280.1"
/db_xref="GI:386597774"
/db_xref="GeneID:12688591"
/translation="MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFP
SLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYA
LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSK
AKKQ"
misc_feature 26794..27213
/gene="lspA"
/locus_tag="ECOK1_0023"
/note="lipoprotein signal peptidase; Reviewed; Region:
lspA; PRK00376"
/db_xref="CDD:234739"
gene 27336..27785
/gene="fkpB"
/locus_tag="ECOK1_0024"
/db_xref="GeneID:12688592"
CDS 27336..27785
/gene="fkpB"
/locus_tag="ECOK1_0024"
/EC_number="5.2.1.8"
/note="identified by similarity to SP:P22563; match to
protein family HMM PF00254"
/codon_start=1
/transl_table=11
/product="FKBP-type 16 kDa peptidyl-prolyl cis-trans
isomerase"
/protein_id="YP_006099281.1"
/db_xref="GI:386597775"
/db_xref="GeneID:12688592"
/translation="MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASL
SEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFT
AMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA"
misc_feature 27336..27782
/gene="fkpB"
/locus_tag="ECOK1_0024"
/note="FKBP-type peptidyl-prolyl cis-trans isomerase;
Provisional; Region: PRK15095"
/db_xref="CDD:237908"
misc_feature 27342..>27551
/gene="fkpB"
/locus_tag="ECOK1_0024"
/note="FKBP-type peptidyl-prolyl cis-trans isomerase;
Region: FKBP_C; pfam00254"
/db_xref="CDD:215821"
gene 27787..28737
/gene="ispH"
/locus_tag="ECOK1_0025"
/db_xref="GeneID:12688593"
CDS 27787..28737
/gene="ispH"
/locus_tag="ECOK1_0025"
/EC_number="1.17.1.2"
/note="identified by similarity to SP:P62623; match to
protein family HMM PF02401; match to protein family HMM
TIGR00216"
/codon_start=1
/transl_table=11
/product="4-hydroxy-3-methylbut-2-enyl diphosphate
reductase"
/protein_id="YP_006099282.1"
/db_xref="GI:386597776"
/db_xref="GeneID:12688593"
/translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
VVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVL
VVGSKNSSNSNRLAELAQRMGKRAFLIDDATDIQEEWVKEAKCVGVTAGASAPDILVQ
NVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD"
misc_feature 27787..28689
/gene="ispH"
/locus_tag="ECOK1_0025"
/note="4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
Reviewed; Region: ispH; PRK01045"
/db_xref="CDD:179212"
misc_feature 27793..28641
/gene="ispH"
/locus_tag="ECOK1_0025"
/note="(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate
reductase (IPP and DMAPP forming); Region: ispH_lytB;
TIGR00216"
/db_xref="CDD:161769"
gene 28803..29717
/gene="rihC"
/locus_tag="ECOK1_0026"
/db_xref="GeneID:12688594"
CDS 28803..29717
/gene="rihC"
/locus_tag="ECOK1_0026"
/EC_number="3.2.-.-"
/note="identified by similarity to SP:P0C0W2; match to
protein family HMM PF01156"
/codon_start=1
/transl_table=11
/product="nonspecific ribonucleoside hydrolase RihC"
/protein_id="YP_006099283.1"
/db_xref="GI:386597777"
/db_xref="GeneID:12688594"
/translation="MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEK
TTRNALQLLHFWNVDIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRQPLGIP
AFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTP
NAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALF
SHYRSGSMQSGLRMHDLCAIAWLVRPELFTLKPCFVAVETQGEFTSGTTVVDIDGCLG
KPANVQVALDLDVKGFQQWVAEVLALAL"
misc_feature 28812..29702
/gene="rihC"
/locus_tag="ECOK1_0026"
/note="nuc_hydro_IU_UC_XIUA: inosine-uridine preferring,
xanthosine-inosine-uridine-adenosine-preferring and,
uridine-cytidine preferring nucleoside hydrolases.
Nucleoside hydrolases cleave the N-glycosidic bond in
nucleosides generating ribose and the...; Region:
nuc_hydro_IU_UC_XIUA; cd02651"
/db_xref="CDD:29579"
misc_feature order(28830..28832,28842..28847,28917..28919,29040..29042,
29169..29171,29271..29273,29289..29291,29295..29297,
29502..29504)
/gene="rihC"
/locus_tag="ECOK1_0026"
/note="active site"
/db_xref="CDD:29579"
misc_feature order(29010..29012,29202..29204,29325..29327,29571..29573,
29577..29582,29589..29591)
/gene="rihC"
/locus_tag="ECOK1_0026"
/note="tetramer interface [polypeptide binding]; other
site"
/db_xref="CDD:29579"
gene 29740..30105
/locus_tag="ECOK1_0027"
/db_xref="GeneID:12688595"
CDS 29740..30105
/locus_tag="ECOK1_0027"
/note="identified by match to protein family HMM PF05656"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099284.1"
/db_xref="GI:386597778"
/db_xref="GeneID:12688595"
/translation="MTYGEAYLEGWKNIFNYEGVSNRFEFWSFMIGSGVICLLPLLCW
WLAVTINNDYGVFIFFALPASFILTLIFAIPAIALAVRRMHDIGYSGWWVTIVVLIPV
TGVILLILCCLPSKSQDQA"
misc_feature 29776..30096
/locus_tag="ECOK1_0027"
/note="Protein of unknown function (DUF805); Region:
DUF805; pfam05656"
/db_xref="CDD:203300"
gene 30266..31087
/gene="dapB"
/locus_tag="ECOK1_0028"
/db_xref="GeneID:12688596"
CDS 30266..31087
/gene="dapB"
/locus_tag="ECOK1_0028"
/EC_number="1.3.1.26"
/note="identified by similarity to SP:P04036; match to
protein family HMM PF01113; match to protein family HMM
PF05173; match to protein family HMM TIGR00036"
/codon_start=1
/transl_table=11
/product="dihydrodipicolinate reductase"
/protein_id="YP_006099285.1"
/db_xref="GI:386597779"
/db_xref="GeneID:12688596"
/translation="MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSL
LGSDAGELAGAGKTGVTVQSSLDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIG
TTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVG
EHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL"
misc_feature 30281..31075
/gene="dapB"
/locus_tag="ECOK1_0028"
/note="Dihydrodipicolinate reductase [Amino acid transport
and metabolism]; Region: DapB; COG0289"
/db_xref="CDD:223366"
misc_feature 30281..30601
/gene="dapB"
/locus_tag="ECOK1_0028"
/note="Dihydrodipicolinate reductase, N-terminus; Region:
DapB_N; pfam01113"
/db_xref="CDD:216304"
misc_feature 30659..31069
/gene="dapB"
/locus_tag="ECOK1_0028"
/note="Dihydrodipicolinate reductase, C-terminus; Region:
DapB_C; pfam05173"
/db_xref="CDD:218479"
gene complement(31099..31281)
/locus_tag="ECOK1_0029"
/db_xref="GeneID:12688597"
CDS complement(31099..31281)
/locus_tag="ECOK1_0029"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099286.1"
/db_xref="GI:386597780"
/db_xref="GeneID:12688597"
/translation="MSRKKWTKWSKFTLKQQKQNTKHVIFSICIRFKSITLKIKGPKI
KALYIQRIKCVVFASP"
gene 31543..32691
/gene="carA"
/locus_tag="ECOK1_0030"
/db_xref="GeneID:12688598"
CDS 31543..32691
/gene="carA"
/locus_tag="ECOK1_0030"
/EC_number="6.3.5.5"
/note="identified by similarity to SP:P0A6F1; match to
protein family HMM PF00117; match to protein family HMM
PF00988; match to protein family HMM TIGR01368"
/codon_start=1
/transl_table=11
/product="carbamoyl-phosphate synthase small subunit"
/protein_id="YP_006099287.1"
/db_xref="GI:386597781"
/db_xref="GeneID:12688598"
/translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
DPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
EVTTAEPYSWTQGSWTLTGGLPEAKKEDELPYHVVAYDFGAKRNILRMLVDRGCRLTI
VPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLA
LASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFD
GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIALIEQYRKTAK"
misc_feature 31543..32664
/gene="carA"
/locus_tag="ECOK1_0030"
/note="carbamoyl phosphate synthase small subunit;
Reviewed; Region: PRK12564"
/db_xref="CDD:237139"
misc_feature 31549..31938
/gene="carA"
/locus_tag="ECOK1_0030"
/note="Carbamoyl-phosphate synthase small chain, CPSase
domain; Region: CPSase_sm_chain; smart01097"
/db_xref="CDD:198165"
misc_feature 32122..32655
/gene="carA"
/locus_tag="ECOK1_0030"
/note="Small chain of the glutamine-dependent form of
carbamoyl phosphate synthase, CPSase II; Region:
GATase1_CPSase; cd01744"
/db_xref="CDD:153215"
misc_feature order(32347..32349,32599..32601,32605..32607)
/gene="carA"
/locus_tag="ECOK1_0030"
/note="catalytic site [active]"
/db_xref="CDD:153215"
misc_feature order(32422..32424,32428..32430,32449..32451,32455..32457,
32536..32538,32614..32619,32623..32628)
/gene="carA"
/locus_tag="ECOK1_0030"
/note="subunit interface [polypeptide binding]; other
site"
/db_xref="CDD:153215"
gene 32709..35930
/gene="carB"
/locus_tag="ECOK1_0031"
/db_xref="GeneID:12688599"
CDS 32709..35930
/gene="carB"
/locus_tag="ECOK1_0031"
/EC_number="6.3.5.5"
/note="identified by similarity to SP:P00968; match to
protein family HMM PF00289; match to protein family HMM
PF02142; match to protein family HMM PF02786; match to
protein family HMM PF02787; match to protein family HMM
TIGR01369"
/codon_start=1
/transl_table=11
/product="carbamoyl-phosphate synthase large subunit"
/protein_id="YP_006099288.1"
/db_xref="GI:386597782"
/db_xref="GeneID:12688599"
/translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
ERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHSMEEALAVAA
EVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEM
EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVD
GVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLHAEFLRQLKRKGFADARLAKLAGV
REAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLG
GGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLE
DVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAV
ERLKLKQPANATVTTIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQT
AVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPA
YTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKA
TGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRST
GEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELD
ATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIR
RSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK"
misc_feature 32709..35915
/gene="carB"
/locus_tag="ECOK1_0031"
/note="carbamoyl phosphate synthase large subunit;
Reviewed; Region: carB; PRK05294"
/db_xref="CDD:179998"
misc_feature 32727..33074
/gene="carB"
/locus_tag="ECOK1_0031"
/note="Carbamoyl-phosphate synthase L chain, N-terminal
domain; Region: CPSase_L_chain; pfam00289"
/db_xref="CDD:201133"
misc_feature 33078..33632
/gene="carB"
/locus_tag="ECOK1_0031"
/note="ATP-grasp domain; Region: ATP-grasp_4; pfam13535"
/db_xref="CDD:205713"
misc_feature 33978..34349
/gene="carB"
/locus_tag="ECOK1_0031"
/note="Carbamoyl-phosphate synthetase large chain,
oligomerisation domain; Region: CPSase_L_D3; pfam02787"
/db_xref="CDD:202396"
misc_feature 34386..34712
/gene="carB"
/locus_tag="ECOK1_0031"
/note="Carbamoyl-phosphate synthase L chain, N-terminal
domain; Region: CPSase_L_chain; pfam00289"
/db_xref="CDD:201133"
misc_feature 34719..35243
/gene="carB"
/locus_tag="ECOK1_0031"
/note="ATP-grasp domain; Region: ATP-grasp_4; pfam13535"
/db_xref="CDD:205713"
misc_feature 35535..35864
/gene="carB"
/locus_tag="ECOK1_0031"
/note="Methylglyoxal synthase-like domain from type II
glutamine-dependent carbamoyl phosphate synthetase (CSP).
CSP, a CarA and CarB heterodimer, catalyzes the production
of carbamoyl phosphate which is subsequently employed in
the metabolic pathways...; Region: MGS_CPS_II; cd01424"
/db_xref="CDD:29636"
misc_feature order(35550..35552,35568..35570,35628..35630,35634..35639,
35685..35687,35751..35759)
/gene="carB"
/locus_tag="ECOK1_0031"
/note="IMP binding site; other site"
/db_xref="CDD:29636"
misc_feature order(35631..35633,35643..35645,35667..35669,35673..35678,
35682..35684,35718..35720)
/gene="carB"
/locus_tag="ECOK1_0031"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:29636"
misc_feature order(35826..35828,35841..35843,35853..35855)
/gene="carB"
/locus_tag="ECOK1_0031"
/note="interdomain contacts; other site"
/db_xref="CDD:29636"
misc_feature 35826..35834
/gene="carB"
/locus_tag="ECOK1_0031"
/note="partial ornithine binding site; other site"
/db_xref="CDD:29636"
gene 36154..36612
/locus_tag="ECOK1_0032"
/db_xref="GeneID:12688600"
CDS 36154..36612
/locus_tag="ECOK1_0032"
/note="identified by match to protein family HMM PF01797"
/codon_start=1
/transl_table=11
/product="IS200, transposase"
/protein_id="YP_006099289.1"
/db_xref="GI:386597783"
/db_xref="GeneID:12688600"
/translation="MGNEKSLAHTRWNCKYHIVFAPKYRRQVFYREKRRAIGCILRKL
CEWKSVRILEAECCADHIHMLVEIPPKMSVSGFMGYLKGKSSLMPYEQFGDLKFKYRN
REFWCRGYYVDTVGKNTAKIQDYIKHQLEEDKMGEQLSIPYPGSPFTGRK"
misc_feature 36187..36540
/locus_tag="ECOK1_0032"
/note="Transposase IS200 like; Region: Y1_Tnp; pfam01797"
/db_xref="CDD:216708"
gene 36902..37297
/gene="caiF"
/locus_tag="ECOK1_0033"
/db_xref="GeneID:12688601"
CDS 36902..37297
/gene="caiF"
/locus_tag="ECOK1_0033"
/note="identified by similarity to SP:P0AE58"
/codon_start=1
/transl_table=11
/product="transcriptional activatory protein CaiF"
/protein_id="YP_006099290.1"
/db_xref="GI:386597784"
/db_xref="GeneID:12688601"
/translation="MCEGCVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNT
LTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSRDKLVGVR
KTPRIPAVPLTELNREQKWQMMLSKSMRR"
misc_feature 36956..37294
/gene="caiF"
/locus_tag="ECOK1_0033"
/note="DNA-binding transcriptional activator CaiF;
Provisional; Region: PRK11476"
/db_xref="CDD:183154"
gene complement(37416..38006)
/gene="paaY"
/locus_tag="ECOK1_0034"
/db_xref="GeneID:12688602"
CDS complement(37416..38006)
/gene="paaY"
/locus_tag="ECOK1_0034"
/note="identified by similarity to SP:P77181; match to
protein family HMM PF00132"
/codon_start=1
/transl_table=11
/product="phenylacetic acid degradation protein PaaY"
/protein_id="YP_006099291.1"
/db_xref="GI:386597785"
/db_xref="GeneID:12688602"
/translation="MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLR
GDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSV
IMDGAVIGEESIVAAMSFVKAGFRGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
DLVGRCHAALHETQPLRQMEENRPRLQGTTDVTPKR"
misc_feature complement(37419..38006)
/gene="paaY"
/locus_tag="ECOK1_0034"
/note="carnitine operon protein CaiE; Provisional; Region:
PRK13627"
/db_xref="CDD:184189"
misc_feature complement(37512..37976)
/gene="paaY"
/locus_tag="ECOK1_0034"
/note="paaY-like: This group is composed by
uncharacterized proteins with similarity to the protein
product of the E. coli paaY gene, which is part of the paa
gene cluster responsible for phenylacetic acid
degradation. Proteins in this group are expected to...;
Region: LbH_paaY_like; cd04745"
/db_xref="CDD:100058"
misc_feature complement(order(37710..37712,37746..37748,37752..37763,
37812..37814,37824..37829,37869..37871,37875..37877,
37881..37886,37893..37895,37929..37931,37938..37943,
37947..37949,37953..37955))
/gene="paaY"
/locus_tag="ECOK1_0034"
/note="putative trimer interface [polypeptide binding];
other site"
/db_xref="CDD:100058"
misc_feature complement(order(37746..37748,37761..37763,37812..37814))
/gene="paaY"
/locus_tag="ECOK1_0034"
/note="putative metal binding site [ion binding]; other
site"
/db_xref="CDD:100058"
gene complement(38012..38905)
/gene="caiD"
/locus_tag="ECOK1_0035"
/db_xref="GeneID:12688603"
CDS complement(38012..38905)
/gene="caiD"
/locus_tag="ECOK1_0035"
/EC_number="4.2.1.-"
/note="identified by similarity to SP:P31551; match to
protein family HMM PF00378"
/codon_start=1
/transl_table=11
/product="carnitinyl-CoA dehydratase"
/protein_id="YP_006099292.1"
/db_xref="GI:386597786"
/db_xref="GeneID:12688603"
/translation="MKRQGTTLSANNHALKQYAFFAGMLSSLKKQKWRKGMSESLHLT
RNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDDPQLRVAIITGAGEKFFSAGWDL
KAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADN
ASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMTGRRMGAEEALRWGVVNRVVSQ
AELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMPVEEAYRYIRSGVLKHYPSVLHS
EDAIEGPLAFAEKRDPVWKGR"
misc_feature complement(38015..38797)
/gene="caiD"
/locus_tag="ECOK1_0035"
/note="carnitinyl-CoA dehydratase; Provisional; Region:
PRK03580"
/db_xref="CDD:179599"
misc_feature complement(38210..38785)
/gene="caiD"
/locus_tag="ECOK1_0035"
/note="Crotonase/Enoyl-Coenzyme A (CoA) hydratase
superfamily. This superfamily contains a diverse set of
enzymes including enoyl-CoA hydratase, napthoate synthase,
methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA
dehydratase, and dienoyl-CoA isomerase; Region:
crotonase-like; cd06558"
/db_xref="CDD:119339"
misc_feature complement(order(38396..38398,38405..38410,38474..38482,
38486..38488,38600..38614,38624..38626,38723..38725,
38729..38731))
/gene="caiD"
/locus_tag="ECOK1_0035"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:119339"
misc_feature complement(order(38474..38476,38606..38608))
/gene="caiD"
/locus_tag="ECOK1_0035"
/note="oxyanion hole (OAH) forming residues; other site"
/db_xref="CDD:119339"
misc_feature complement(order(38210..38215,38222..38224,38267..38269,
38276..38278,38309..38311,38318..38323,38327..38332,
38336..38341,38354..38359,38363..38371,38375..38377,
38393..38404,38438..38449,38510..38512,38534..38536))
/gene="caiD"
/locus_tag="ECOK1_0035"
/note="trimer interface [polypeptide binding]; other site"
/db_xref="CDD:119339"
gene complement(38906..40474)
/locus_tag="ECOK1_0036"
/db_xref="GeneID:12688604"
CDS complement(38906..40474)
/locus_tag="ECOK1_0036"
/note="identified by similarity to SP:P31552; match to
protein family HMM PF00501"
/codon_start=1
/transl_table=11
/product="putative crotonobetaine/carnitine-CoA ligase"
/protein_id="YP_006099293.1"
/db_xref="GI:386597787"
/db_xref="GeneID:12688604"
/translation="MDRGAMDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYS
YLELNQEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLL
REESTWILQNSQACLLVTSAQFYPMYQQIQQEDASQLRHICLIDMALPADDGVSSFTQ
LKNQQPATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRD
DDVYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPM
MIRTLMVQPPSANDRQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGII
GDRPGDKRRWPSIGRAGFCYEAEIRDDHNRPLPAGELGEICIKGVPGKTIFKEYFLNP
KATAKVLEADGWLHTGDTGYRDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPK
IQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFCFCEQNMAKFKVPSYLEIRKDL
PRNCSGKIIRKNLK"
misc_feature complement(38909..40459)
/locus_tag="ECOK1_0036"
/note="putative crotonobetaine/carnitine-CoA ligase;
Validated; Region: caiC; PRK08008"
/db_xref="CDD:181195"
misc_feature complement(38909..40354)
/locus_tag="ECOK1_0036"
/note="Uncharacterized subfamily of fatty acid CoA ligase
(FACL); Region: FACL_DitJ_like; cd05934"
/db_xref="CDD:213300"
misc_feature complement(order(39893..39898,39902..39919,39926..39928))
/locus_tag="ECOK1_0036"
/note="acyl-activating enzyme (AAE) consensus motif; other
site"
/db_xref="CDD:213300"
misc_feature complement(order(38930..38932,39170..39172,39203..39205,
39212..39214,39248..39250,39494..39511,39569..39574,
39917..39919))
/locus_tag="ECOK1_0036"
/note="putative AMP binding site [chemical binding]; other
site"
/db_xref="CDD:213300"
misc_feature complement(order(38987..38989,39170..39181,39203..39205,
39212..39214,39248..39250,39494..39511,39569..39574,
39629..39631,39638..39643,39647..39649,39794..39799,
39917..39919))
/locus_tag="ECOK1_0036"
/note="putative active site [active]"
/db_xref="CDD:213300"
misc_feature complement(order(38987..38989,39005..39007,39173..39181,
39572..39574,39629..39631,39638..39643,39797..39799))
/locus_tag="ECOK1_0036"
/note="putative CoA binding site [chemical binding]; other
site"
/db_xref="CDD:213300"
gene complement(40532..41749)
/gene="caiB"
/locus_tag="ECOK1_0037"
/db_xref="GeneID:12688605"
CDS complement(40532..41749)
/gene="caiB"
/locus_tag="ECOK1_0037"
/EC_number="2.8.3.-"
/note="identified by similarity to SP:P31572; match to
protein family HMM PF02515"
/codon_start=1
/transl_table=11
/product="crotonobetainyl-CoA:carnitine CoA-transferase"
/protein_id="YP_006099294.1"
/db_xref="GI:386597788"
/db_xref="GeneID:12688605"
/translation="MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
RRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
MPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNG
GEMCPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQIAECFKDIGLAHLLGTPEIPE
GTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQY
VARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDI
QELVSKGLAKVED"
misc_feature complement(40535..41749)
/gene="caiB"
/locus_tag="ECOK1_0037"
/note="crotonobetainyl-CoA:carnitine CoA-transferase;
Provisional; Region: PRK03525"
/db_xref="CDD:179589"
misc_feature complement(41006..41545)
/gene="caiB"
/locus_tag="ECOK1_0037"
/note="CoA-transferase family III; Region: CoA_transf_3;
pfam02515"
/db_xref="CDD:217078"
gene complement(41877..43019)
/gene="caiA"
/locus_tag="ECOK1_0038"
/db_xref="GeneID:12688606"
CDS complement(41877..43019)
/gene="caiA"
/locus_tag="ECOK1_0038"
/EC_number="1.3.99.-"
/note="identified by similarity to SP:P60587; match to
protein family HMM PF00441; match to protein family HMM
PF02770; match to protein family HMM PF02771; match to
protein family HMM PF08028"
/codon_start=1
/transl_table=11
/product="crotonobetainyl-CoA dehydrogenase"
/protein_id="YP_006099295.1"
/db_xref="GI:386597789"
/db_xref="GeneID:12688606"
/translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
ALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELD
EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRF
QLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQ
VLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
misc_feature complement(41880..43019)
/gene="caiA"
/locus_tag="ECOK1_0038"
/note="crotonobetainyl-CoA dehydrogenase; Validated;
Region: PRK03354"
/db_xref="CDD:179566"
misc_feature complement(41901..43001)
/gene="caiA"
/locus_tag="ECOK1_0038"
/note="Acyl-CoA dehydrogenase; Region: ACAD; cd00567"
/db_xref="CDD:173838"
misc_feature complement(order(41925..41927,41931..41933,41937..41945,
42549..42551,42555..42557,42648..42650,42654..42656,
42870..42872))
/gene="caiA"
/locus_tag="ECOK1_0038"
/note="active site"
/db_xref="CDD:173838"
gene complement(43050..44564)
/gene="caiT"
/locus_tag="ECOK1_0039"
/db_xref="GeneID:12688607"
CDS complement(43050..44564)
/gene="caiT"
/locus_tag="ECOK1_0039"
/note="identified by similarity to SP:P31553; match to
protein family HMM PF02028; match to protein family HMM
TIGR00842"
/codon_start=1
/transl_table=11
/product="L-carnitine/gamma-butyrobetaine antiporter"
/protein_id="YP_006099296.1"
/db_xref="GI:386597790"
/db_xref="GeneID:12688607"
/translation="MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVF
SYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSA
AVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYF
FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTEC
MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
SGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIF
LARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVAR
AIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRI
GWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD"
misc_feature complement(43053..44564)
/gene="caiT"
/locus_tag="ECOK1_0039"
/note="L-carnitine/gamma-butyrobetaine antiporter;
Provisional; Region: PRK03356"
/db_xref="CDD:179568"
gene 45037..45807
/gene="fixA"
/locus_tag="ECOK1_0040"
/db_xref="GeneID:12688608"
CDS 45037..45807
/gene="fixA"
/locus_tag="ECOK1_0040"
/note="identified by similarity to SP:P60566; match to
protein family HMM PF01012"
/codon_start=1
/transl_table=11
/product="electron transfer flavoprotein subunit beta"
/protein_id="YP_006099297.1"
/db_xref="GI:386597791"
/db_xref="GeneID:12688608"
/translation="MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEA
ACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTAS
VLAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVE
RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAA
WSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI"
misc_feature 45040..45657
/gene="fixA"
/locus_tag="ECOK1_0040"
/note="The electron transfer flavoprotein (ETF) serves as
a specific electron acceptor for various mitochondrial
dehydrogenases. ETF transfers electrons to the main
respiratory chain via ETF-ubiquinone oxidoreductase. ETF
is an heterodimer that consists of an...; Region:
ETF_beta; cd01714"
/db_xref="CDD:238847"
misc_feature order(45052..45057,45139..45141,45148..45150,45220..45222,
45388..45393,45397..45402,45415..45426)
/gene="fixA"
/locus_tag="ECOK1_0040"
/note="Ligand binding site [chemical binding]; other site"
/db_xref="CDD:238847"
misc_feature 45124..45597
/gene="fixA"
/locus_tag="ECOK1_0040"
/note="Electron transfer flavoprotein domain; Region: ETF;
pfam01012"
/db_xref="CDD:216243"
gene 45822..46763
/gene="fixB"
/locus_tag="ECOK1_0041"
/db_xref="GeneID:12688609"
CDS 45822..46763
/gene="fixB"
/locus_tag="ECOK1_0041"
/note="identified by similarity to SP:P31574; match to
protein family HMM PF00766; match to protein family HMM
PF01012"
/codon_start=1
/transl_table=11
/product="electron transfer flavoprotein subunit alpha"
/protein_id="YP_006099298.1"
/db_xref="GI:386597792"
/db_xref="GeneID:12688609"
/translation="MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGTQA
IQLGANHVWKLSGKPDERMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYR
LNAAVSNDASAVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLC
KAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQT
IFAINKDKNAPIFQYADYGIVGDAVKILPALTVALAR"
misc_feature 45822..46760
/gene="fixB"
/locus_tag="ECOK1_0041"
/note="putative electron transfer flavoprotein FixB;
Provisional; Region: fixB; PRK03363"
/db_xref="CDD:179570"
misc_feature <45951..46316
/gene="fixB"
/locus_tag="ECOK1_0041"
/note="The electron transfer flavoprotein (ETF) serves as
a specific electron acceptor for various mitochondrial
dehydrogenases. ETF transfers electrons to the main
respiratory chain via ETF-ubiquinone oxidoreductase. ETF
is an heterodimer that consists of an...; Region: ETF;
cd01985"
/db_xref="CDD:30172"
misc_feature order(46077..46082,46086..46091,46095..46106)
/gene="fixB"
/locus_tag="ECOK1_0041"
/note="Ligand binding site [chemical binding]; other site"
/db_xref="CDD:30172"
misc_feature 46386..46646
/gene="fixB"
/locus_tag="ECOK1_0041"
/note="Electron transfer flavoprotein FAD-binding domain;
Region: ETF_alpha; pfam00766"
/db_xref="CDD:189709"
gene 46814..48100
/gene="fixC"
/locus_tag="ECOK1_0042"
/db_xref="GeneID:12688610"
CDS 46814..48100
/gene="fixC"
/locus_tag="ECOK1_0042"
/note="identified by similarity to SP:P68644; match to
protein family HMM PF01134; match to protein family HMM
PF01266; match to protein family HMM PF01494; match to
protein family HMM PF03486"
/codon_start=1
/transl_table=11
/product="protein FixC"
/protein_id="YP_006099299.1"
/db_xref="GI:386597793"
/db_xref="GeneID:12688610"
/translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
VTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRS
YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
GVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTD
GLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
SAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSA
MKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFT
IDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL"
misc_feature 46814..48097
/gene="fixC"
/locus_tag="ECOK1_0042"
/note="putative oxidoreductase FixC; Provisional; Region:
PRK10157"
/db_xref="CDD:182273"
gene 48097..48384
/gene="fixX"
/locus_tag="ECOK1_0043"
/db_xref="GeneID:12688611"
CDS 48097..48384
/gene="fixX"
/locus_tag="ECOK1_0043"
/codon_start=1
/transl_table=11
/product="ferredoxin-like protein FixX"
/protein_id="YP_006099300.1"
/db_xref="GI:386597794"
/db_xref="GeneID:12688611"
/translation="MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACP
AGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG"
misc_feature 48097..48381
/gene="fixX"
/locus_tag="ECOK1_0043"
/note="ferredoxin-like protein FixX; Provisional; Region:
PRK15449"
/db_xref="CDD:185346"
gene 48443..49774
/locus_tag="ECOK1_0044"
/db_xref="GeneID:12688612"
CDS 48443..49774
/locus_tag="ECOK1_0044"
/note="identified by match to protein family HMM PF00083;
match to protein family HMM PF07690"
/codon_start=1
/transl_table=11
/product="major facilitator family transporter"
/protein_id="YP_006099301.1"
/db_xref="GI:386597795"
/db_xref="GeneID:12688612"
/translation="MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQL
TPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMF
VSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFG
EPVAFEEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLG
VGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGI
WLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPI
FINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG"
misc_feature 48500..49705
/locus_tag="ECOK1_0044"
/note="The Major Facilitator Superfamily (MFS) is a large
and diverse group of secondary transporters that includes
uniporters, symporters, and antiporters. MFS proteins
facilitate the transport across cytoplasmic or internal
membranes of a variety of...; Region: MFS; cd06174"
/db_xref="CDD:119392"
misc_feature 48518..49747
/locus_tag="ECOK1_0044"
/note="Sugar (and other) transporter; Region: Sugar_tr;
pfam00083"
/db_xref="CDD:215702"
misc_feature order(48542..48544,48551..48559,48563..48568,48617..48619,
48626..48631,48638..48640,48650..48655,48659..48664,
48800..48805,48812..48817,48824..48829,48836..48838,
48872..48877,48884..48889,48905..48907,49208..49210,
49217..49222,49229..49234,49241..49243,49283..49285,
49295..49297,49307..49309,49316..49318,49328..49330,
49475..49477,49484..49489,49496..49498,49508..49513,
49520..49522,49553..49558,49565..49570,49577..49582,
49589..49591)
/locus_tag="ECOK1_0044"
/note="putative substrate translocation pore; other site"
/db_xref="CDD:119392"
gene 49882..50412
/gene="kefF"
/locus_tag="ECOK1_0045"
/db_xref="GeneID:12688613"
CDS 49882..50412
/gene="kefF"
/locus_tag="ECOK1_0045"
/note="identified by similarity to SP:P0A754; match to
protein family HMM PF02525"
/codon_start=1
/transl_table=11
/product="glutathione-regulated potassium-efflux system
ancillary protein kefF"
/protein_id="YP_006099302.1"
/db_xref="GI:386597796"
/db_xref="GeneID:12688613"
/translation="MILIIYAHPYPHYSHANKRMLEQARTLEGVEIRSLYQLYPDFNI
DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLW
AVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
RHYKQRLLEWQEAHHG"
misc_feature 49882..50409
/gene="kefF"
/locus_tag="ECOK1_0045"
/note="glutathione-regulated potassium-efflux system
ancillary protein KefF; Provisional; Region: PRK00871"
/db_xref="CDD:179148"
gene 50405..52267
/gene="kefC"
/locus_tag="ECOK1_0046"
/db_xref="GeneID:12688614"
CDS 50405..52267
/gene="kefC"
/locus_tag="ECOK1_0046"
/note="identified by similarity to SP:P03819; match to
protein family HMM PF00999; match to protein family HMM
PF02254; match to protein family HMM TIGR00932"
/codon_start=1
/transl_table=11
/product="glutathione-regulated potassium-efflux system
protein KefC"
/protein_id="YP_006099303.1"
/db_xref="GI:386597797"
/db_xref="GeneID:12688614"
/translation="MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
GLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLG
LFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAI
PLVAMIPLLAASSASTTMGAFVLSALKVAGALALVVLLGRYVTRPALRFVARSGLREV
FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
FIGVGMSIDFGTLIENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQ
GSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREA
DEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
TRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQ
AGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTK
ARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS"
misc_feature 50405..52264
/gene="kefC"
/locus_tag="ECOK1_0046"
/note="glutathione-regulated potassium-efflux system
protein KefC; Provisional; Region: PRK03562"
/db_xref="CDD:179594"
misc_feature 50441..51259
/gene="kefC"
/locus_tag="ECOK1_0046"
/note="transporter, monovalent cation:proton antiporter-2
(CPA2) family; Region: 2a37; TIGR00932"
/db_xref="CDD:162117"
misc_feature 51608..51937
/gene="kefC"
/locus_tag="ECOK1_0046"
/note="TrkA-N domain; Region: TrkA_N; pfam02254"
/db_xref="CDD:202177"
gene 52459..52938
/gene="folA"
/locus_tag="ECOK1_0047"
/db_xref="GeneID:12688615"
CDS 52459..52938
/gene="folA"
/locus_tag="ECOK1_0047"
/EC_number="1.5.1.3"
/note="identified by similarity to SP:P0ABQ4; match to
protein family HMM PF00186"
/codon_start=1
/transl_table=11
/product="dihydrofolate reductase"
/protein_id="YP_006099304.1"
/db_xref="GI:386597798"
/db_xref="GeneID:12688615"
/translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGR
HTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQ
FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
misc_feature 52459..52935
/gene="folA"
/locus_tag="ECOK1_0047"
/note="Dihydrofolate reductase [Coenzyme metabolism];
Region: FolA; COG0262"
/db_xref="CDD:223340"
misc_feature 52462..52929
/gene="folA"
/locus_tag="ECOK1_0047"
/note="Dihydrofolate reductase (DHFR). Reduces
7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH
as a cofactor. This is an essential step in the
biosynthesis of deoxythymidine phosphate since
5,6,7,8-tetrahydrofolate is required to regenerate 5;
Region: DHFR; cd00209"
/db_xref="CDD:238127"
misc_feature order(52471..52473,52522..52524,52537..52539,52627..52629,
52738..52740,52756..52758,52795..52797)
/gene="folA"
/locus_tag="ECOK1_0047"
/note="folate binding site [chemical binding]; other site"
/db_xref="CDD:238127"
misc_feature order(52477..52479,52498..52500,52588..52596,52648..52650,
52741..52752)
/gene="folA"
/locus_tag="ECOK1_0047"
/note="NADP+ binding site [chemical binding]; other site"
/db_xref="CDD:238127"
gene 53024..53257
/gene="ccdA"
/locus_tag="ECOK1_0048"
/db_xref="GeneID:12688616"
CDS 53024..53257
/gene="ccdA"
/locus_tag="ECOK1_0048"
/note="identified by similarity to SP:P62552; match to
protein family HMM PF07362"
/codon_start=1
/transl_table=11
/product="post-segregation antitoxin CcdA"
/protein_id="YP_006099305.1"
/db_xref="GI:386597799"
/db_xref="GeneID:12688616"
/translation="MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKH
AATRWREENAEAIAALNQLADETGCFSDEYRSF"
misc_feature 53039..53254
/gene="ccdA"
/locus_tag="ECOK1_0048"
/note="Post-segregation antitoxin CcdA; Region: CcdA;
pfam07362"
/db_xref="CDD:148779"
gene 53260..53575
/locus_tag="ECOK1_0050"
/note="cytotoxic protein CcdB homolog, authentic
frameshift; this gene contains a frame shift which is not
the result of sequencing error; identified by similarity
to SP:Q52043"
/pseudo
/db_xref="GeneID:12688617"
gene complement(53572..54420)
/gene="apaH"
/locus_tag="ECOK1_0049"
/db_xref="GeneID:12688618"
CDS complement(53572..54420)
/gene="apaH"
/locus_tag="ECOK1_0049"
/EC_number="3.6.1.41"
/note="identified by similarity to SP:P05637; match to
protein family HMM PF00149; match to protein family HMM
TIGR00668"
/codon_start=1
/transl_table=11
/product="bis(5'-nucleosyl)-tetraphosphatase
(symmetrical)"
/protein_id="YP_006099306.1"
/db_xref="GI:386597800"
/db_xref="GeneID:12688618"
/translation="MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPG
SLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
RRQPLLQIDKEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVA
EEYNIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLSE
GEAVAS"
misc_feature complement(53584..54420)
/gene="apaH"
/locus_tag="ECOK1_0049"
/note="bis(5'-nucleosyl)-tetraphosphatase (symmetrical);
Region: apaH; TIGR00668"
/db_xref="CDD:161988"
misc_feature complement(53644..54414)
/gene="apaH"
/locus_tag="ECOK1_0049"
/note="Escherichia coli ApaH and related proteins,
metallophosphatase domain; Region: MPP_ApaH; cd07422"
/db_xref="CDD:163665"
misc_feature complement(order(53674..53676,53689..53691,53740..53742,
54061..54063,54223..54228,54298..54303,54310..54312,
54391..54393,54397..54399))
/gene="apaH"
/locus_tag="ECOK1_0049"
/note="active site"
/db_xref="CDD:163665"
misc_feature complement(order(53740..53742,54061..54063,54226..54228,
54310..54312,54391..54393,54397..54399))
/gene="apaH"
/locus_tag="ECOK1_0049"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:163665"
gene complement(54427..54804)
/gene="apaG"
/locus_tag="ECOK1_0051"
/db_xref="GeneID:12688619"
CDS complement(54427..54804)
/gene="apaG"
/locus_tag="ECOK1_0051"
/note="identified by similarity to SP:P62675; match to
protein family HMM PF04379"
/codon_start=1
/transl_table=11
/product="protein ApaG"
/protein_id="YP_006099307.1"
/db_xref="GI:386597801"
/db_xref="GeneID:12688619"
/translation="MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQ
LLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMI
DENGVPFSIDIPVFRLAVPTLIH"
misc_feature complement(54430..54804)
/gene="apaG"
/locus_tag="ECOK1_0051"
/note="CO2+/MG2+ efflux protein ApaG; Reviewed; Region:
apaG; PRK05461"
/db_xref="CDD:180098"
gene complement(54807..55628)
/gene="ksgA"
/locus_tag="ECOK1_0052"
/db_xref="GeneID:12688620"
CDS complement(54807..55628)
/gene="ksgA"
/locus_tag="ECOK1_0052"
/EC_number="2.1.1.-"
/note="identified by match to protein family HMM PF00398;
match to protein family HMM TIGR00755"
/codon_start=1
/transl_table=11
/product="dimethyladenosine transferase"
/protein_id="YP_006099308.1"
/db_xref="GI:386597802"
/db_xref="GeneID:12688620"
/translation="MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEI
GPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAA
KMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAF
NQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES"
misc_feature complement(54828..55628)
/gene="ksgA"
/locus_tag="ECOK1_0052"
/note="16S ribosomal RNA methyltransferase KsgA/Dim1
family protein; Reviewed; Region: ksgA; PRK00274"
/db_xref="CDD:234708"
misc_feature complement(54822..55598)
/gene="ksgA"
/locus_tag="ECOK1_0052"
/note="Dimethyladenosine transferase (rRNA methylation)
[Translation, ribosomal structure and biogenesis]; Region:
KsgA; COG0030"
/db_xref="CDD:223109"
gene complement(55625..56614)
/gene="pdxA"
/locus_tag="ECOK1_0053"
/db_xref="GeneID:12688621"
CDS complement(55625..56614)
/gene="pdxA"
/locus_tag="ECOK1_0053"
/EC_number="1.1.1.262"
/note="identified by similarity to SP:P19624; match to
protein family HMM PF04166; match to protein family HMM
TIGR00557"
/codon_start=1
/transl_table=11
/product="4-hydroxythreonine-4-phosphate dehydrogenase"
/protein_id="YP_006099309.1"
/db_xref="GI:386597803"
/db_xref="GeneID:12688621"
/translation="MVKTQRVVITPGEPAGIGPDLIVQLAQREWPVELVVCADATLLT
DRAAMLGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRESVTVGQLAVENGHYVVETLA
RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
GTEEIDTIIPVLNELREQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
GFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ"
misc_feature complement(55628..56614)
/gene="pdxA"
/locus_tag="ECOK1_0053"
/note="4-hydroxythreonine-4-phosphate dehydrogenase;
Reviewed; Region: pdxA; PRK00232"
/db_xref="CDD:234696"
misc_feature complement(55646..56596)
/gene="pdxA"
/locus_tag="ECOK1_0053"
/note="4-hydroxythreonine-4-phosphate dehydrogenase;
Validated; Region: pdxA; PRK03743"
/db_xref="CDD:179641"
gene complement(56614..57900)
/gene="surA"
/locus_tag="ECOK1_0054"
/db_xref="GeneID:12688622"
CDS complement(56614..57900)
/gene="surA"
/locus_tag="ECOK1_0054"
/EC_number="5.2.1.8"
/note="identified by similarity to SP:Q3Z5V6; match to
protein family HMM PF00639; match to protein family HMM
PF09312"
/codon_start=1
/transl_table=11
/product="chaperone/peptidyl-prolyl cis-trans isomerase
SurA"
/protein_id="YP_006099310.1"
/db_xref="GI:386597804"
/db_xref="GeneID:12688622"
/translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
LMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIAN
IAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIA
HSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGE
SKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGS
ANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAA
QKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN"
misc_feature complement(56617..57846)
/gene="surA"
/locus_tag="ECOK1_0054"
/note="peptidyl-prolyl cis-trans isomerase SurA;
Provisional; Region: PRK10770"
/db_xref="CDD:236758"
misc_feature complement(57475..57828)
/gene="surA"
/locus_tag="ECOK1_0054"
/note="SurA N-terminal domain; Region: SurA_N; pfam09312"
/db_xref="CDD:150092"
misc_feature complement(57085..57369)
/gene="surA"
/locus_tag="ECOK1_0054"
/note="PPIC-type PPIASE domain; Region: Rotamase;
pfam00639"
/db_xref="CDD:216038"
misc_feature complement(56755..57036)
/gene="surA"
/locus_tag="ECOK1_0054"
/note="PPIC-type PPIASE domain; Region: Rotamase;
pfam00639"
/db_xref="CDD:216038"
gene complement(57953..60307)
/gene="imp"
/locus_tag="ECOK1_0055"
/db_xref="GeneID:12688623"
CDS complement(57953..60307)
/gene="imp"
/locus_tag="ECOK1_0055"
/note="identified by similarity to SP:P31554; match to
protein family HMM PF03968; match to protein family HMM
PF04453"
/codon_start=1
/transl_table=11
/product="LPS-assembly protein"
/protein_id="YP_006099311.1"
/db_xref="GI:386597805"
/db_xref="GeneID:12688623"
/translation="MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQ
GDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVR
TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
RYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
PVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
RYLSQAGAGLMELDYLPSDKVYKDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKV
SDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEP
QLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTE
AKLLATHYQQTNLDWYNSRNTTKLAESANRVMPQFKVDGRMVFERDMEMLAPGYTQTL
EPRAQYLYVPYRDQSKIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRI
YDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISDRWGLRG
GIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGI
SQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWD
NDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL"
misc_feature complement(57962..60307)
/gene="imp"
/locus_tag="ECOK1_0055"
/note="LPS assembly outer membrane complex protein LptD;
Provisional; Region: PRK03761"
/db_xref="CDD:179645"
misc_feature complement(59723..60151)
/gene="imp"
/locus_tag="ECOK1_0055"
/note="OstA-like protein; Region: OstA; pfam03968"
/db_xref="CDD:190815"
misc_feature complement(58217..59380)
/gene="imp"
/locus_tag="ECOK1_0055"
/note="Organic solvent tolerance protein; Region: OstA_C;
pfam04453"
/db_xref="CDD:190995"
gene 60562..61377
/gene="djlA"
/locus_tag="ECOK1_0056"
/db_xref="GeneID:12688624"
CDS 60562..61377
/gene="djlA"
/locus_tag="ECOK1_0056"
/note="identified by similarity to SP:P31680; match to
protein family HMM PF00226"
/codon_start=1
/transl_table=11
/product="protein DjlA, DnaJ family"
/protein_id="YP_006099312.1"
/db_xref="GI:386597806"
/db_xref="GeneID:12688624"
/translation="MQYWGKIIGVAVALIMGGGFWGVVLGLLIGHMFDKARSRKMAWF
ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFR
VGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEE
LGISRAQFDQFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDA
TTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK"
misc_feature 60562..61374
/gene="djlA"
/locus_tag="ECOK1_0056"
/note="Dna-J like membrane chaperone protein; Provisional;
Region: djlA; PRK09430"
/db_xref="CDD:181850"
misc_feature 60730..61047
/gene="djlA"
/locus_tag="ECOK1_0056"
/note="N-terminal tellurium resistance protein terB-like
domain of heat shock DnaJ-like proteins; Region:
terB_like_DjlA; cd07316"
/db_xref="CDD:143585"
misc_feature order(60766..60768,60787..60789,60988..60990,61009..61011)
/gene="djlA"
/locus_tag="ECOK1_0056"
/note="putative metal binding site [ion binding]; other
site"
/db_xref="CDD:143585"
misc_feature 61186..61347
/gene="djlA"
/locus_tag="ECOK1_0056"
/note="DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock
protein 40) proteins are highly conserved and play crucial
roles in protein translation, folding, unfolding,
translocation, and degradation. They act primarily by
stimulating the ATPase activity of Hsp70s; Region: DnaJ;
cd06257"
/db_xref="CDD:99751"
misc_feature order(61258..61266,61312..61314,61321..61326,61333..61338)
/gene="djlA"
/locus_tag="ECOK1_0056"
/note="HSP70 interaction site [polypeptide binding]; other
site"
/db_xref="CDD:99751"
gene complement(61527..62186)
/locus_tag="ECOK1_0057"
/db_xref="GeneID:12688625"
CDS complement(61527..62186)
/locus_tag="ECOK1_0057"
/note="identified by match to protein family HMM PF00849"
/codon_start=1
/transl_table=11
/product="RluA family pseudouridine synthase"
/protein_id="YP_006099313.1"
/db_xref="GI:386597807"
/db_xref="GeneID:12688625"
/translation="MGMENYNPPQDPWLVVLYQDDHIMVVNKPSGLLSVPGRLEEHKD
SVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAD
F"
misc_feature complement(61530..>62162)
/locus_tag="ECOK1_0057"
/note="Pseudouridylate synthases, 23S RNA-specific
[Translation, ribosomal structure and biogenesis]; Region:
RluA; COG0564"
/db_xref="CDD:30910"
misc_feature complement(61581..62120)
/locus_tag="ECOK1_0057"
/note="Pseudouridine synthase, RsuA/RluD family; Region:
PseudoU_synth_RluCD_like; cd02869"
/db_xref="CDD:211346"
misc_feature complement(order(61692..61694,61995..62006))
/locus_tag="ECOK1_0057"
/note="active site"
/db_xref="CDD:211346"
gene complement(62198..65104)
/gene="rapA"
/locus_tag="ECOK1_0058"
/db_xref="GeneID:12688626"
CDS complement(62198..65104)
/gene="rapA"
/locus_tag="ECOK1_0058"
/EC_number="3.6.1.-"
/note="identified by similarity to SP:P60240; match to
protein family HMM PF00176; match to protein family HMM
PF00271; match to protein family HMM PF04851"
/codon_start=1
/transl_table=11
/product="RNA polymerase associated protein RapA"
/protein_id="YP_006099314.1"
/db_xref="GI:386597808"
/db_xref="GeneID:12688626"
/translation="MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYA
RSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFL
DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
MLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDL
LVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPN
RFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSD
SEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKV
SGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLV
ICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
SEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
YHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLE
QGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVL
TPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGS
STISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
EFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKL
SAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ"
misc_feature complement(62207..65101)
/gene="rapA"
/locus_tag="ECOK1_0058"
/note="ATP-dependent helicase HepA; Validated; Region:
PRK04914"
/db_xref="CDD:235319"
misc_feature complement(64157..64588)
/gene="rapA"
/locus_tag="ECOK1_0058"
/note="DEAD-like helicases superfamily. A diverse family
of proteins involved in ATP-dependent RNA or DNA
unwinding. This domain contains the ATP-binding region;
Region: DEXDc; cd00046"
/db_xref="CDD:238005"
misc_feature complement(64553..64567)
/gene="rapA"
/locus_tag="ECOK1_0058"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:238005"
misc_feature complement(64256..64267)
/gene="rapA"
/locus_tag="ECOK1_0058"
/note="putative Mg++ binding site [ion binding]; other
site"
/db_xref="CDD:238005"
misc_feature complement(63299..63667)
/gene="rapA"
/locus_tag="ECOK1_0058"
/note="Helicase superfamily c-terminal domain; associated
with DEXDc-, DEAD-, and DEAH-box proteins, yeast
initiation factor 4A, Ski2p, and Hepatitis C virus NS3
helicases; this domain is found in a wide variety of
helicases and helicase related proteins; may...; Region:
HELICc; cd00079"
/db_xref="CDD:238034"
misc_feature complement(order(63410..63418,63497..63502,63563..63574))
/gene="rapA"
/locus_tag="ECOK1_0058"
/note="nucleotide binding region [chemical binding]; other
site"
/db_xref="CDD:238034"
misc_feature complement(order(63308..63310,63317..63319,63329..63331,
63392..63394))
/gene="rapA"
/locus_tag="ECOK1_0058"
/note="ATP-binding site [chemical binding]; other site"
/db_xref="CDD:238034"
gene complement(65268..67619)
/gene="polB"
/locus_tag="ECOK1_0059"
/db_xref="GeneID:12688627"
CDS complement(65268..67619)
/gene="polB"
/locus_tag="ECOK1_0059"
/EC_number="2.7.7.7"
/note="identified by similarity to SP:P21189; match to
protein family HMM PF00136; match to protein family HMM
PF03104"
/codon_start=1
/transl_table=11
/product="DNA polymerase II"
/protein_id="YP_006099315.1"
/db_xref="GI:386597809"
/db_xref="GeneID:12688627"
/translation="MAQAGFILTRHWRDTPQGTEVSFLLATDNGPLQVTLAPQESVAF
IPADHVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVT
VYEADVRPPERYLMERFITSPVWVEGDMRNGAIVNARLKPHPDYRPPLKWVSIDIETT
RHGELYCIGLEGCGQRIVYMLGPENGDASALDFELEYVASRPLLLEKLNAWFATHDPD
VIIGWNVVQFDLRMLQKHAERYRIPLRLGRDNSELEWREHGFKNDVFFAQAKGRLIID
GIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLK
DCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLG
EVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
RFFDPRLASSITMRGHQIMRQTKTLIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIG
RALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEG
DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDTRL
VYRKRLRRPLSEYQRNVPPHVRAARLADEENHKRGRPLQYQNRGTIKYVWTTNGPEPL
DYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF"
misc_feature complement(65271..67619)
/gene="polB"
/locus_tag="ECOK1_0059"
/note="DNA polymerase II; Reviewed; Region: PRK05762"
/db_xref="CDD:180243"
misc_feature complement(66588..67178)
/gene="polB"
/locus_tag="ECOK1_0059"
/note="DEDDy 3'-5' exonuclease domain of Escherichia coli
DNA polymerase II and similar bacterial family-B DNA
polymerases; Region: DNA_polB_II_exo; cd05784"
/db_xref="CDD:99827"
misc_feature complement(order(66615..66617,66627..66629,66741..66746,
66933..66941,66948..66953,67143..67154))
/gene="polB"
/locus_tag="ECOK1_0059"
/note="active site"
/db_xref="CDD:99827"
misc_feature complement(order(66615..66617,66627..66629,66933..66935,
67146..67148,67152..67154))
/gene="polB"
/locus_tag="ECOK1_0059"
/note="catalytic site [active]"
/db_xref="CDD:99827"
misc_feature complement(order(66615..66617,66627..66629,66741..66746,
66936..66941,66948..66953,67143..67151))
/gene="polB"
/locus_tag="ECOK1_0059"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:99827"
misc_feature complement(65313..66431)
/gene="polB"
/locus_tag="ECOK1_0059"
/note="DNA polymerase type-II subfamily catalytic domain.
Bacteria contain five DNA polymerases (I, II, III, IV and
V). DNA polymerase II (Pol II) is a prototype for the
B-family of polymerases. The role of Pol II in a variety
of cellular activities, such as...; Region: POLBc_Pol_II;
cd05537"
/db_xref="CDD:99920"
misc_feature complement(order(65979..65981,66129..66131,66141..66143,
66189..66191,66348..66356,66363..66365))
/gene="polB"
/locus_tag="ECOK1_0059"
/note="active site"
/db_xref="CDD:99920"
misc_feature complement(order(65979..65981,65985..65987))
/gene="polB"
/locus_tag="ECOK1_0059"
/note="metal-binding site"
/db_xref="CDD:99920"
gene complement(67694..68389)
/gene="araD"
/locus_tag="ECOK1_0060"
/db_xref="GeneID:12688628"
CDS complement(67694..68389)
/gene="araD"
/locus_tag="ECOK1_0060"
/EC_number="5.1.3.4"
/note="identified by similarity to SP:P08203; match to
protein family HMM PF00596; match to protein family HMM
TIGR00760"
/codon_start=1
/transl_table=11
/product="L-ribulose-5-phosphate 4-epimerase"
/protein_id="YP_006099316.1"
/db_xref="GI:386597810"
/db_xref="GeneID:12688628"
/translation="MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRGRGVLVIKPS
GVDYSTMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHAT
IWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKH
YLRKHGAKAYYGQ"
misc_feature complement(67697..68389)
/gene="araD"
/locus_tag="ECOK1_0060"
/note="L-ribulose-5-phosphate 4-epimerase; Reviewed;
Region: araD; PRK08193"
/db_xref="CDD:181280"
misc_feature complement(67721..68383)
/gene="araD"
/locus_tag="ECOK1_0060"
/note="Class II Aldolase and Adducin head (N-terminal)
domain. Aldolases are ubiquitous enzymes catalyzing
central steps of carbohydrate metabolism. Based on
enzymatic mechanisms, this superfamily has been divided
into two distinct classes (Class I and II); Region:
Aldolase_II; cd00398"
/db_xref="CDD:29521"
misc_feature complement(order(67733..67735,67793..67795,67814..67816,
67826..67828,67847..67849,67880..67882,67997..67999,
68039..68044,68048..68050,68069..68077,68090..68095,
68099..68101,68240..68245,68249..68251,68321..68323,
68345..68347,68357..68359))
/gene="araD"
/locus_tag="ECOK1_0060"
/note="intersubunit interface [polypeptide binding]; other
site"
/db_xref="CDD:29521"
misc_feature complement(order(67877..67879,68099..68101,68105..68107,
68162..68170,68255..68260,68306..68308))
/gene="araD"
/locus_tag="ECOK1_0060"
/note="active site"
/db_xref="CDD:29521"
misc_feature complement(order(67877..67879,68099..68101,68105..68107))
/gene="araD"
/locus_tag="ECOK1_0060"
/note="Zn2+ binding site [ion binding]; other site"
/db_xref="CDD:29521"
gene complement(68589..70091)
/gene="araA"
/locus_tag="ECOK1_0061"
/db_xref="GeneID:12688629"
CDS complement(68589..70091)
/gene="araA"
/locus_tag="ECOK1_0061"
/EC_number="5.3.1.4"
/note="identified by match to protein family HMM PF02610"
/codon_start=1
/transl_table=11
/product="L-arabinose isomerase"
/protein_id="YP_006099317.1"
/db_xref="GI:386597811"
/db_xref="GeneID:12688629"
/translation="MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKL
PCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQ
FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
NSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFT
TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
YTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAI
VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
TVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR"
misc_feature complement(68592..70091)
/gene="araA"
/locus_tag="ECOK1_0061"
/note="L-arabinose isomerase; Provisional; Region:
PRK02929"
/db_xref="CDD:179503"
misc_feature complement(68619..70073)
/gene="araA"
/locus_tag="ECOK1_0061"
/note="L-Arabinose isomerase (AI) catalyzes the
isomerization of L-arabinose to L-ribulose, the first
reaction in its conversion into D-xylulose-5-phosphate, an
intermediate in the pentose phosphate pathway, which
allows L-arabinose to be used as a carbon...; Region:
L-arabinose_isomerase; cd03557"
/db_xref="CDD:239619"
misc_feature complement(order(69249..69254,69279..69281,69444..69446,
69456..69476,69495..69497,69504..69506,69540..69542,
69561..69563,69669..69674,69828..69830,69888..69890,
69897..69899,69909..69911))
/gene="araA"
/locus_tag="ECOK1_0061"
/note="putative hexamer (dimer of trimers) interface
[polypeptide binding]; other site"
/db_xref="CDD:239619"
misc_feature complement(order(68619..68624,68691..68693,68745..68747,
68754..68756,68763..68765,68772..68777,68820..68822,
68826..68831,68835..68837,68892..68900,69075..69092,
69522..69533,69615..69617,69648..69650,69654..69656,
69669..69671,69675..69680,69687..69689,69696..69701,
69708..69713,69729..69731,69738..69746,69753..69755,
69759..69761,69765..69767,69774..69776,69780..69782,
69828..69839,69843..69845))
/gene="araA"
/locus_tag="ECOK1_0061"
/note="trimer interface [polypeptide binding]; other site"
/db_xref="CDD:239619"
misc_feature complement(order(68742..68747,69093..69095,69174..69176,
69255..69257,69843..69845))
/gene="araA"
/locus_tag="ECOK1_0061"
/note="putative substrate binding site [chemical binding];
other site"
/db_xref="CDD:239619"
misc_feature complement(order(68742..68744,69093..69095,69174..69176))
/gene="araA"
/locus_tag="ECOK1_0061"
/note="putative metal binding site [ion binding]; other
site"
/db_xref="CDD:239619"
gene complement(70102..71802)
/gene="araB"
/locus_tag="ECOK1_0062"
/db_xref="GeneID:12688630"
CDS complement(70102..71802)
/gene="araB"
/locus_tag="ECOK1_0062"
/EC_number="2.7.1.16"
/note="identified by similarity to SP:P08204; match to
protein family HMM PF00370; match to protein family HMM
PF02782; match to protein family HMM TIGR01234"
/codon_start=1
/transl_table=11
/product="L-ribulokinase"
/protein_id="YP_006099318.1"
/db_xref="GI:386597812"
/db_xref="GeneID:12688630"
/translation="MAIAIGLDFGSDSVRALAVDCATGEEIATSVEWYPRWQKGQFCD
APNNQFRHHPRDYIESMEAALKTVLAELSAEQRAAVVGIGVDTTGSTPAPIDADGNVL
ALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKI
LHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLP
PASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCH
MGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAG
QSAFGDIYAWFGRVLSWPLEQLAAQHPELKEQINASQKQLLPALTEAWAKNPSLDHLP
VVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATTFGARAIMECFTDQGI
AVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
SAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYPPTSAPAQAAQAVPTL
"
misc_feature complement(70153..71802)
/gene="araB"
/locus_tag="ECOK1_0062"
/note="ribulokinase; Provisional; Region: PRK04123"
/db_xref="CDD:179742"
misc_feature complement(70261..71799)
/gene="araB"
/locus_tag="ECOK1_0062"
/note="Ribulokinases; belongs to the FGGY family of
carbohydrate kinases; Region: FGGY_RBK; cd07781"
/db_xref="CDD:198358"
misc_feature complement(order(70261..70266,70300..70317,70321..70326,
70330..70338,70342..70344,70585..70587,70597..70599,
70807..70815,70825..70827,70831..70857,70864..70866,
70870..70872,70960..70968,70972..70974,70996..70998,
71002..71004,71059..71073,71167..71175,71185..71190,
71197..71202,71338..71340,71353..71355,71359..71370,
71545..71562,71716..71718,71728..71733,71746..71748,
71752..71754,71758..71760,71779..71781,71785..71787,
71791..71793))
/gene="araB"
/locus_tag="ECOK1_0062"
/note="N- and C-terminal domain interface [polypeptide
binding]; other site"
/db_xref="CDD:198358"
misc_feature complement(order(70336..70338,70408..70410,70420..70428,
70669..70671,70774..70776,70786..70788,70909..70911,
70918..70926,70978..70983,71446..71448,71533..71535,
71539..71541,71758..71760,71764..71775,71779..71781))
/gene="araB"
/locus_tag="ECOK1_0062"
/note="active site"
/db_xref="CDD:198358"
misc_feature complement(order(70408..70410,70420..70428,70660..70662,
70666..70671,70774..70779,70783..70788,70918..70926,
70981..70983,71758..71760,71764..71775,71779..71781))
/gene="araB"
/locus_tag="ECOK1_0062"
/note="MgATP binding site [chemical binding]; other site"
/db_xref="CDD:198358"
misc_feature complement(order(70981..70983,71770..71772,71779..71781))
/gene="araB"
/locus_tag="ECOK1_0062"
/note="catalytic site [active]"
/db_xref="CDD:198358"
misc_feature complement(order(70981..70983,71779..71781))
/gene="araB"
/locus_tag="ECOK1_0062"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:198358"
misc_feature complement(order(70807..70809,70909..70911,70918..70920,
70978..70983,71182..71184,71341..71343,71446..71448,
71533..71541,71770..71775))
/gene="araB"
/locus_tag="ECOK1_0062"
/note="carbohydrate binding site [chemical binding]; other
site"
/db_xref="CDD:198358"
misc_feature complement(order(70534..70542,70546..70572,70606..70611,
70624..70626,70630..70632,70747..70764,70771..70773,
70783..70785))
/gene="araB"
/locus_tag="ECOK1_0062"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:198358"
gene 72141..72986
/gene="araC"
/locus_tag="ECOK1_0063"
/db_xref="GeneID:12688631"
CDS 72141..72986
/gene="araC"
/locus_tag="ECOK1_0063"
/note="identified by similarity to SP:P11765; match to
protein family HMM PF00165; match to protein family HMM
PF02311"
/codon_start=1
/transl_table=11
/product="arabinose operon regulatory protein"
/protein_id="YP_006099319.1"
/db_xref="GI:386597813"
/db_xref="GeneID:12688631"
/translation="MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
YILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAHEWYHQWVYFRPRA
YWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLL
LRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQ
LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
RAGCE"
misc_feature 72141..72983
/gene="araC"
/locus_tag="ECOK1_0063"
/note="DNA-binding transcriptional regulator AraC;
Provisional; Region: PRK10572"
/db_xref="CDD:236717"
misc_feature 72201..72587
/gene="araC"
/locus_tag="ECOK1_0063"
/note="AraC-like ligand binding domain; Region:
AraC_binding; pfam02311"
/db_xref="CDD:145456"
misc_feature 72696..72821
/gene="araC"
/locus_tag="ECOK1_0063"
/note="Bacterial regulatory helix-turn-helix proteins,
AraC family; Region: HTH_AraC; pfam00165"
/db_xref="CDD:215763"
misc_feature 72861..72971
/gene="araC"
/locus_tag="ECOK1_0063"
/note="Bacterial regulatory helix-turn-helix proteins,
AraC family; Region: HTH_AraC; pfam00165"
/db_xref="CDD:215763"
gene 73251..73373
/locus_tag="ECOK1_0064"
/note="transposase, degenerate; this region contains one
or more premature stops and/or frameshifts"
/pseudo
/db_xref="GeneID:12688632"
gene 73501..74349
/locus_tag="ECOK1_0065"
/db_xref="GeneID:12688633"
CDS 73501..74349
/locus_tag="ECOK1_0065"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099320.1"
/db_xref="GI:386597814"
/db_xref="GeneID:12688633"
/translation="MSKRNDITDGIFATTKKYGLVYTEELGWIDLGHAQGQDARILKR
KLEQEHFSTYYDEFHDWYFPVDYHQEMGIRKKILGVDLTFHTGVYTKVMVRSCLSPTL
KARVALTLMYGTAKRFEAWQNSFIFNWYTDSGFSAEDLVSDLIGFYRVFGTGPDPLLL
AKPLSYTKALQIWDTYGAPGNFKNTEFTPFLFTTHPPFKKNQLIKKKLPEWLNYIKPL
DESFSILLYNQYNNRPVTNYYKDKNRINHELYSSLSSSGAIKFSESPFERPLFLFLNP
HYPHRS"
gene 74933..75697
/locus_tag="ECOK1_0066"
/db_xref="GeneID:12688634"
CDS 74933..75697
/locus_tag="ECOK1_0066"
/note="identified by similarity to SP:P30149; match to
protein family HMM PF09335"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099321.1"
/db_xref="GI:386597815"
/db_xref="GeneID:12688634"
/translation="MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAG
LGALIGSGELSFWYAWLAGIIGCLMGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTE
HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPQFYFLPGI
LAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLL
WLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGV"
misc_feature 74954..75550
/locus_tag="ECOK1_0066"
/note="Uncharacterized membrane-associated protein
[Function unknown]; Region: DedA; COG0586"
/db_xref="CDD:30931"
misc_feature 75038..75415
/locus_tag="ECOK1_0066"
/note="SNARE associated Golgi protein; Region:
SNARE_assoc; pfam09335"
/db_xref="CDD:204201"
gene complement(75811..76509)
/gene="thiQ"
/locus_tag="ECOK1_0067"
/db_xref="GeneID:12688635"
CDS complement(75811..76509)
/gene="thiQ"
/locus_tag="ECOK1_0067"
/note="identified by similarity to SP:P31548; match to
protein family HMM PF00005; match to protein family HMM
TIGR01277"
/codon_start=1
/transl_table=11
/product="thiamine ABC transporter ATP-binding protein"
/protein_id="YP_006099322.1"
/db_xref="GI:386597816"
/db_xref="GeneID:12688635"
/translation="MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNL
IAGFLTPASGLLTIDDVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKL
NAAQQKKMHAIAHQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
DPALRQEMLTLVSSSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTDELL
SGKASASALLGIKG"
misc_feature complement(75862..76509)
/gene="thiQ"
/locus_tag="ECOK1_0067"
/note="thiamine transporter ATP-binding subunit;
Provisional; Region: thiQ; PRK10771"
/db_xref="CDD:182716"
misc_feature complement(75874..76506)
/gene="thiQ"
/locus_tag="ECOK1_0067"
/note="ATP-binding cassette domain of the thiamine
transport system; Region: ABC_ThiQ_thiamine_transporter;
cd03298"
/db_xref="CDD:213265"
misc_feature complement(76393..76416)
/gene="thiQ"
/locus_tag="ECOK1_0067"
/note="Walker A/P-loop; other site"
/db_xref="CDD:213265"
misc_feature complement(order(75946..75948,76045..76050,76276..76278,
76390..76398,76402..76407))
/gene="thiQ"
/locus_tag="ECOK1_0067"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:213265"
misc_feature complement(76276..76287)
/gene="thiQ"
/locus_tag="ECOK1_0067"
/note="Q-loop/lid; other site"
/db_xref="CDD:213265"
misc_feature complement(76093..76122)
/gene="thiQ"
/locus_tag="ECOK1_0067"
/note="ABC transporter signature motif; other site"
/db_xref="CDD:213265"
misc_feature complement(76045..76062)
/gene="thiQ"
/locus_tag="ECOK1_0067"
/note="Walker B; other site"
/db_xref="CDD:213265"
misc_feature complement(76027..76038)
/gene="thiQ"
/locus_tag="ECOK1_0067"
/note="D-loop; other site"
/db_xref="CDD:213265"
misc_feature complement(75940..75960)
/gene="thiQ"
/locus_tag="ECOK1_0067"
/note="H-loop/switch region; other site"
/db_xref="CDD:213265"
gene complement(76493..78103)
/gene="thiP"
/locus_tag="ECOK1_0068"
/db_xref="GeneID:12688636"
CDS complement(76493..78103)
/gene="thiP"
/locus_tag="ECOK1_0068"
/note="identified by similarity to SP:P31549; match to
protein family HMM PF00528; match to protein family HMM
TIGR01253"
/codon_start=1
/transl_table=11
/product="thiamine/thiamine pyrophosphate ABC transporter,
permease protein"
/protein_id="YP_006099323.1"
/db_xref="GI:386597817"
/db_xref="GeneID:12688636"
/translation="MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGDWV
AVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRQMLLRLCAMTLIL
PVLVAVFGILSVYGRQGWLASLWQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
ALENIPGEQRQLAAQLGMHGWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
GGPQATTIELAIYQALSYDYDPARAAMLALIQMVCCLGLVLLSQRLSKAIAPGTTLLQ
GWRDPDDRLHSRICDTALIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTS
LRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFL
LLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRL
KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGA
VTALILLLLCFLLFTVIEKIPGRNVKTD"
misc_feature complement(76499..78073)
/gene="thiP"
/locus_tag="ECOK1_0068"
/note="thiamine transporter membrane protein; Reviewed;
Region: thiP; PRK09433"
/db_xref="CDD:181853"
misc_feature complement(77339..77935)
/gene="thiP"
/locus_tag="ECOK1_0068"
/note="Transmembrane subunit (TM) found in Periplasmic
Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
transporters which generally bind type 2 PBPs. These types
of transporters consist of a PBP, two TMs, and two
cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
cd06261"
/db_xref="CDD:119394"
misc_feature complement(order(77339..77344,77351..77356,77363..77368,
77372..77377,77384..77389,77417..77422,77456..77461,
77468..77479,77498..77500,77507..77512,77552..77554,
77603..77605,77612..77617,77627..77629,77633..77638,
77645..77647,77651..77653,77660..77665,77768..77770,
77774..77779,77786..77815,77819..77830,77858..77860,
77873..77878,77885..77890))
/gene="thiP"
/locus_tag="ECOK1_0068"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:119394"
misc_feature complement(order(77462..77479,77768..77812))
/gene="thiP"
/locus_tag="ECOK1_0068"
/note="conserved gate region; other site"
/db_xref="CDD:119394"
misc_feature complement(order(77387..77389,77417..77419,77426..77428,
77459..77461,77678..77680,77768..77770))
/gene="thiP"
/locus_tag="ECOK1_0068"
/note="putative PBP binding loops; other site"
/db_xref="CDD:119394"
misc_feature complement(order(77531..77533,77543..77548,77564..77602))
/gene="thiP"
/locus_tag="ECOK1_0068"
/note="ABC-ATPase subunit interface; other site"
/db_xref="CDD:119394"
misc_feature complement(76586..77113)
/gene="thiP"
/locus_tag="ECOK1_0068"
/note="Transmembrane subunit (TM) found in Periplasmic
Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
transporters which generally bind type 2 PBPs. These types
of transporters consist of a PBP, two TMs, and two
cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
cd06261"
/db_xref="CDD:119394"
misc_feature complement(order(76586..76588,76616..76621,76658..76663,
76670..76681,76700..76702,76709..76714,76754..76756,
76805..76807,76814..76819,76829..76831,76835..76840,
76847..76849,76853..76855,76859..76864,76931..76933,
76937..76942,76949..76978,76982..76993,77033..77035,
77048..77053,77060..77065))
/gene="thiP"
/locus_tag="ECOK1_0068"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:119394"
misc_feature complement(order(76664..76681,76931..76975))
/gene="thiP"
/locus_tag="ECOK1_0068"
/note="conserved gate region; other site"
/db_xref="CDD:119394"
misc_feature complement(order(76586..76588,76616..76618,76625..76627,
76661..76663,76877..76879,76931..76933))
/gene="thiP"
/locus_tag="ECOK1_0068"
/note="putative PBP binding loops; other site"
/db_xref="CDD:119394"
misc_feature complement(order(76733..76735,76745..76750,76766..76804))
/gene="thiP"
/locus_tag="ECOK1_0068"
/note="ABC-ATPase subunit interface; other site"
/db_xref="CDD:119394"
gene complement(78079..79062)
/gene="thiB"
/locus_tag="ECOK1_0069"
/db_xref="GeneID:12688637"
CDS complement(78079..79062)
/gene="thiB"
/locus_tag="ECOK1_0069"
/note="identified by similarity to SP:P31550; match to
protein family HMM PF01547; match to protein family HMM
TIGR01254; match to protein family HMM TIGR01276"
/codon_start=1
/transl_table=11
/product="thiamine/thiamine pyrophosphate ABC transporter,
periplasmic thiamine/thiamine pyrophospate-binding
protein"
/protein_id="YP_006099324.1"
/db_xref="GI:386597818"
/db_xref="GeneID:12688637"
/translation="MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAF
EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTELFAKSGVA
AEAVNVPGGWNNDTFVPYDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYEDPRT
STPGLGLLLWMQKVYGDNAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
PAYHILEEKKDNYAATNFIEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIP
TGNWMYPVANVTLPAGFEQLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR"
misc_feature complement(78082..79026)
/gene="thiB"
/locus_tag="ECOK1_0069"
/note="thiamine transporter substrate binding subunit;
Provisional; Region: tbpA; PRK11205"
/db_xref="CDD:183039"
misc_feature complement(78082..79014)
/gene="thiB"
/locus_tag="ECOK1_0069"
/note="ABC-type thiamine transport system, periplasmic
component [Coenzyme metabolism]; Region: TbpA; COG4143"
/db_xref="CDD:33896"
gene complement(79226..80881)
/gene="sgrR"
/locus_tag="ECOK1_0070"
/db_xref="GeneID:12688638"
CDS complement(79226..80881)
/gene="sgrR"
/locus_tag="ECOK1_0070"
/note="identified by similarity to SP:P33595; match to
protein family HMM PF00496"
/codon_start=1
/transl_table=11
/product="sugar transport-related sRNA regulator SgrR"
/protein_id="YP_006099325.1"
/db_xref="GI:386597819"
/db_xref="GeneID:12688638"
/translation="MPSARLQQQFIRLWQCCEGKSQETTLNELAALLSCSRRHMRTLL
NTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAT
VRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIA
NIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRN
STNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEG
CYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHART
IKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIES
DIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVA
SKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
misc_feature complement(79229..80881)
/gene="sgrR"
/locus_tag="ECOK1_0070"
/note="transcriptional regulator SgrR; Provisional;
Region: PRK13626"
/db_xref="CDD:184188"
misc_feature complement(80528..80869)
/gene="sgrR"
/locus_tag="ECOK1_0070"
/note="Sugar transport-related sRNA regulator N-term;
Region: SgrR_N; pfam12793"
/db_xref="CDD:193269"
misc_feature complement(79241..80536)
/gene="sgrR"
/locus_tag="ECOK1_0070"
/note="The C-terminal solute-binding domain of DNA-binding
transcriptional regulator SgrR is related to the ABC-type
oligopeptide-binding proteins and contains the type 2
periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507"
/db_xref="CDD:173872"
gene 80970..81101
/locus_tag="ECOK1_0071"
/db_xref="GeneID:12688639"
CDS 80970..81101
/locus_tag="ECOK1_0071"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099326.1"
/db_xref="GI:386597820"
/db_xref="GeneID:12688639"
/translation="MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEELMQWEGSHSDY"
gene complement(81209..81814)
/gene="leuD"
/locus_tag="ECOK1_0072"
/db_xref="GeneID:12688640"
CDS complement(81209..81814)
/gene="leuD"
/locus_tag="ECOK1_0072"
/EC_number="4.2.1.33"
/note="identified by similarity to SP:P30126; match to
protein family HMM PF00694; match to protein family HMM
TIGR00171"
/codon_start=1
/transl_table=11
/product="3-isopropylmalate dehydratase small subunit"
/protein_id="YP_006099327.1"
/db_xref="GI:386597821"
/db_xref="GeneID:12688640"
/translation="MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
NDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
APSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
RFTIDAFRRHCMMNGLDSIGLTLQHDDAIASYEEKQPAFMR"
misc_feature complement(81212..81808)
/gene="leuD"
/locus_tag="ECOK1_0072"
/note="isopropylmalate isomerase small subunit;
Provisional; Region: leuD; PRK01641"
/db_xref="CDD:179314"
misc_feature complement(81371..81772)
/gene="leuD"
/locus_tag="ECOK1_0072"
/note="Aconatase-like swivel domain of 3-isopropylmalate
dehydratase and related uncharacterized proteins.
3-isopropylmalate dehydratase catalyzes the isomerization
between 2-isopropylmalate and 3-isopropylmalate, via the
formation of 2-isopropylmaleate...; Region: IPMI_Swivel;
cd01577"
/db_xref="CDD:238809"
misc_feature complement(81557..81565)
/gene="leuD"
/locus_tag="ECOK1_0072"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:238809"
gene complement(81825..83225)
/gene="leuC"
/locus_tag="ECOK1_0073"
/db_xref="GeneID:12688641"
CDS complement(81825..83225)
/gene="leuC"
/locus_tag="ECOK1_0073"
/EC_number="4.2.1.33"
/note="identified by match to protein family HMM PF00330;
match to protein family HMM TIGR00170"
/codon_start=1
/transl_table=11
/product="3-isopropylmalate dehydratase large subunit"
/protein_id="YP_006099328.1"
/db_xref="GI:386597822"
/db_xref="GeneID:12688641"
/translation="MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGL
RAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNH
PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMT
LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTV
VTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPL
TEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
AAAAVTGHFADIRNIK"
misc_feature complement(81831..83225)
/gene="leuC"
/locus_tag="ECOK1_0073"
/note="3-isopropylmalate dehydratase large subunit;
Reviewed; Region: PRK00402"
/db_xref="CDD:234748"
misc_feature complement(81849..83141)
/gene="leuC"
/locus_tag="ECOK1_0073"
/note="3-isopropylmalate dehydratase catalyzes the
isomerization between 2-isopropylmalate and
3-isopropylmalate; Region: IPMI; cd01583"
/db_xref="CDD:153133"
misc_feature complement(order(81921..81923,81936..81938,81993..81995,
82839..82844,83118..83120,83127..83129))
/gene="leuC"
/locus_tag="ECOK1_0073"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:153133"
misc_feature complement(order(81939..81941,81993..81998,82005..82007,
82185..82187,82836..82838))
/gene="leuC"
/locus_tag="ECOK1_0073"
/note="ligand binding site [chemical binding]; other site"
/db_xref="CDD:153133"
gene complement(83228..84319)
/gene="leuB"
/locus_tag="ECOK1_0074"
/db_xref="GeneID:12688642"
CDS complement(83228..84319)
/gene="leuB"
/locus_tag="ECOK1_0074"
/EC_number="1.1.1.85"
/note="identified by similarity to SP:P30125; match to
protein family HMM PF00180; match to protein family HMM
TIGR00169"
/codon_start=1
/transl_table=11
/product="3-isopropylmalate dehydrogenase"
/protein_id="YP_006099329.1"
/db_xref="GI:386597823"
/db_xref="GeneID:12688642"
/translation="MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYD
VGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHF
KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPD
VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG
FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAASAIERAINRALEEGI
RTGDLARGAAAVSTDEMGDIIARYVAEGV"
misc_feature complement(83234..84313)
/gene="leuB"
/locus_tag="ECOK1_0074"
/note="3-isopropylmalate dehydrogenase; Provisional;
Region: PRK00772"
/db_xref="CDD:179119"
misc_feature complement(83249..84313)
/gene="leuB"
/locus_tag="ECOK1_0074"
/note="tartrate dehydrogenase; Provisional; Region:
PRK08194"
/db_xref="CDD:181281"
gene complement(84319..85890)
/gene="leuA"
/locus_tag="ECOK1_0075"
/db_xref="GeneID:12688643"
CDS complement(84319..85890)
/gene="leuA"
/locus_tag="ECOK1_0075"
/EC_number="2.3.3.13"
/note="identified by match to protein family HMM PF00682;
match to protein family HMM PF08502; match to protein
family HMM TIGR00973"
/codon_start=1
/transl_table=11
/product="2-isopropylmalate synthase"
/protein_id="YP_006099330.1"
/db_xref="GI:386597824"
/db_xref="GeneID:12688643"
/translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVME
VGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIAT
SPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAV
HAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQI
CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
AAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFR
LDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYS
LTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
LQRKAQHNENNKETV"
misc_feature complement(84355..85890)
/gene="leuA"
/locus_tag="ECOK1_0075"
/note="2-isopropylmalate synthase; Validated; Region:
PRK00915"
/db_xref="CDD:234864"
misc_feature complement(85066..85872)
/gene="leuA"
/locus_tag="ECOK1_0075"
/note="2-isopropylmalate synthase (IPMS), N-terminal
catalytic TIM barrel domain; Region: DRE_TIM_IPMS;
cd07940"
/db_xref="CDD:163678"
misc_feature complement(order(85279..85281,85285..85287,85378..85380,
85384..85386,85468..85470,85474..85476,85600..85602,
85666..85668,85759..85761,85840..85842,85849..85854))
/gene="leuA"
/locus_tag="ECOK1_0075"
/note="active site"
/db_xref="CDD:163678"
misc_feature complement(order(85759..85761,85849..85854))
/gene="leuA"
/locus_tag="ECOK1_0075"
/note="catalytic residues [active]"
/db_xref="CDD:163678"
misc_feature complement(order(85279..85281,85285..85287))
/gene="leuA"
/locus_tag="ECOK1_0075"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:163678"
misc_feature complement(84391..84786)
/gene="leuA"
/locus_tag="ECOK1_0075"
/note="LeuA allosteric (dimerisation) domain; Region:
LeuA_dimer; pfam08502"
/db_xref="CDD:219870"
gene complement(85982..86068)
/gene="leuL"
/locus_tag="ECOK1_0076"
/db_xref="GeneID:12688644"
CDS complement(85982..86068)
/gene="leuL"
/locus_tag="ECOK1_0076"
/note="identified by match to protein family HMM PF08054"
/codon_start=1
/transl_table=11
/product="leu operon leader peptide"
/protein_id="YP_006099331.1"
/db_xref="GI:386597825"
/db_xref="GeneID:12688644"
/translation="MTHIVRFIGLLLLNASFLRGRRVSGIQH"
misc_feature complement(85985..86068)
/gene="leuL"
/locus_tag="ECOK1_0076"
/note="leu operon leader peptide; Provisional; Region:
PRK09925"
/db_xref="CDD:137592"
gene 86726..87670
/gene="leuO"
/locus_tag="ECOK1_0077"
/db_xref="GeneID:12688645"
CDS 86726..87670
/gene="leuO"
/locus_tag="ECOK1_0077"
/note="identified by similarity to SP:P10151; match to
protein family HMM PF00126; match to protein family HMM
PF03466"
/codon_start=1
/transl_table=11
/product="transcriptional regulator LeuO"
/protein_id="YP_006099332.1"
/db_xref="GI:386597826"
/db_xref="GeneID:12688645"
/translation="MPEVQTDHPETAELSKPQLRMVDLNLLTVFDAVMQEQNITRAAH
ALGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
SGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDR
FASFSQTWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVL
PLPLKQNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR"
misc_feature 86726..87667
/gene="leuO"
/locus_tag="ECOK1_0077"
/note="leucine transcriptional activator; Reviewed;
Region: leuO; PRK09508"
/db_xref="CDD:181918"
misc_feature 86795..86971
/gene="leuO"
/locus_tag="ECOK1_0077"
/note="Bacterial regulatory helix-turn-helix protein, lysR
family; Region: HTH_1; pfam00126"
/db_xref="CDD:215735"
misc_feature 87062..87658
/gene="leuO"
/locus_tag="ECOK1_0077"
/note="The C-terminal substrate binding domain of
LysR-type transcriptional regulator LeuO, an activator of
leucine synthesis operon, contains the type 2 periplasmic
binding fold; Region: PBP2_LeuO; cd08466"
/db_xref="CDD:176155"
misc_feature order(87080..87082,87086..87091,87101..87103,87275..87277,
87383..87385,87584..87586)
/gene="leuO"
/locus_tag="ECOK1_0077"
/note="putative substrate binding pocket [chemical
binding]; other site"
/db_xref="CDD:176155"
misc_feature order(87083..87085,87092..87097,87104..87109,87116..87121,
87125..87130,87137..87142,87146..87160,87164..87166,
87353..87355,87434..87448,87455..87460,87467..87472,
87479..87481,87521..87523)
/gene="leuO"
/locus_tag="ECOK1_0077"
/note="putative dimerization interface [polypeptide
binding]; other site"
/db_xref="CDD:176155"
gene 87988..89712
/gene="ilvI"
/locus_tag="ECOK1_0078"
/db_xref="GeneID:12688646"
CDS 87988..89712
/gene="ilvI"
/locus_tag="ECOK1_0078"
/EC_number="2.2.1.6"
/note="identified by similarity to SP:P00893; match to
protein family HMM PF00205; match to protein family HMM
PF02775; match to protein family HMM PF02776; match to
protein family HMM TIGR00118"
/codon_start=1
/transl_table=11
/product="acetolactate synthase, large subunit, isozyme
III"
/protein_id="YP_006099333.1"
/db_xref="GI:386597827"
/db_xref="GeneID:12688646"
/translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGID
HVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQ
VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
LPKDILNPANKLPYVWPESVSMRSYNPTTSGHKGQIKRALQTLVAAKKPVVYVGGGAI
TAGCHLQLKEAVEVLNLPVVSSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVI
FAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLEL
LSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTHGDAYVT
SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGS
IQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
EAYGHVGIQISHPQELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
WLSKTERT"
misc_feature 87988..89709
/gene="ilvI"
/locus_tag="ECOK1_0078"
/note="acetolactate synthase 3 catalytic subunit;
Validated; Region: PRK07979"
/db_xref="CDD:181185"
misc_feature 88009..88476
/gene="ilvI"
/locus_tag="ECOK1_0078"
/note="Pyrimidine (PYR) binding domain of POX and related
proteins; Region: TPP_PYR_POX_like; cd07035"
/db_xref="CDD:132918"
misc_feature order(88048..88050,88063..88068,88078..88080,88090..88092,
88117..88137,88144..88146,88153..88158,88165..88170,
88174..88182,88216..88218,88237..88239,88249..88251,
88258..88263)
/gene="ilvI"
/locus_tag="ECOK1_0078"
/note="PYR/PP interface [polypeptide binding]; other site"
/db_xref="CDD:132918"
misc_feature order(88063..88071,88078..88080,88090..88092,88120..88122,
88126..88137,88141..88143,88216..88218,88225..88230,
88234..88239,88246..88248,88348..88350,88357..88359)
/gene="ilvI"
/locus_tag="ECOK1_0078"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:132918"
misc_feature order(88063..88065,88138..88140,88216..88218,88228..88230)
/gene="ilvI"
/locus_tag="ECOK1_0078"
/note="TPP binding site [chemical binding]; other site"
/db_xref="CDD:132918"
misc_feature 88573..88968
/gene="ilvI"
/locus_tag="ECOK1_0078"
/note="Thiamine pyrophosphate enzyme, central domain;
Region: TPP_enzyme_M; pfam00205"
/db_xref="CDD:201080"
misc_feature 89101..89655
/gene="ilvI"
/locus_tag="ECOK1_0078"
/note="Thiamine pyrophosphate (TPP) family,
Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding
module; composed of proteins similar to the large
catalytic subunit of AHAS. AHAS catalyzes the condensation
of two molecules of pyruvate to give the...; Region:
TPP_AHAS; cd02015"
/db_xref="CDD:48178"
misc_feature order(89170..89181,89248..89250,89254..89256,89329..89337,
89344..89346,89410..89412)
/gene="ilvI"
/locus_tag="ECOK1_0078"
/note="TPP-binding site [chemical binding]; other site"
/db_xref="CDD:48178"
misc_feature order(89239..89241,89248..89250,89254..89256,89341..89346,
89350..89355,89374..89376,89491..89496,89506..89508,
89515..89517)
/gene="ilvI"
/locus_tag="ECOK1_0078"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:48178"
gene 89715..90206
/gene="ilvH"
/locus_tag="ECOK1_0079"
/db_xref="GeneID:12688647"
CDS 89715..90206
/gene="ilvH"
/locus_tag="ECOK1_0079"
/EC_number="2.2.1.6"
/note="identified by similarity to SP:P00894; match to
protein family HMM PF01842; match to protein family HMM
TIGR00119"
/codon_start=1
/transl_table=11
/product="acetolactate synthase, small subunit, isozyme
III"
/protein_id="YP_006099334.1"
/db_xref="GI:386597828"
/db_xref="GeneID:12688647"
/translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVK
RNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
IMR"
misc_feature 89715..90200
/gene="ilvH"
/locus_tag="ECOK1_0079"
/note="acetolactate synthase 3 regulatory subunit;
Reviewed; Region: ilvH; PRK11895"
/db_xref="CDD:183365"
misc_feature 89721..89936
/gene="ilvH"
/locus_tag="ECOK1_0079"
/note="N-terminal ACT domain of the Escherichia coli
IlvH-like regulatory subunit of acetohydroxyacid synthase
(AHAS); Region: ACT_AHAS; cd04878"
/db_xref="CDD:153150"
misc_feature order(89739..89741,89745..89747,89760..89762,89799..89804,
89817..89819,89844..89846)
/gene="ilvH"
/locus_tag="ECOK1_0079"
/note="putative valine binding site [chemical binding];
other site"
/db_xref="CDD:153150"
misc_feature order(89751..89756,89763..89765,89784..89786,89793..89795,
89805..89819,89847..89849)
/gene="ilvH"
/locus_tag="ECOK1_0079"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:153150"
misc_feature 89961..90188
/gene="ilvH"
/locus_tag="ECOK1_0079"
/note="Small subunit of acetolactate synthase; Region:
ALS_ss_C; pfam10369"
/db_xref="CDD:204463"
gene 90218..90304
/locus_tag="ECOK1_0080"
/db_xref="GeneID:12688648"
CDS 90218..90304
/locus_tag="ECOK1_0080"
/codon_start=1
/transl_table=11
/product="hypothetical fruR leader peptide"
/protein_id="YP_006099335.1"
/db_xref="GI:386597829"
/db_xref="GeneID:12688648"
/translation="MRNLQPNMSRWAFFAKSVGTWNKSSCRS"
gene 90386..91390
/gene="fruR"
/locus_tag="ECOK1_0081"
/db_xref="GeneID:12688649"
CDS 90386..91390
/gene="fruR"
/locus_tag="ECOK1_0081"
/note="identified by similarity to SP:P0ACP1; match to
protein family HMM PF00356; match to protein family HMM
PF00532; match to protein family HMM TIGR02417"
/codon_start=1
/transl_table=11
/product="fructose repressor"
/protein_id="YP_006099336.1"
/db_xref="GI:386597830"
/db_xref="GeneID:12688649"
/translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYAN
SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDN
ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
"
misc_feature 90386..91369
/gene="fruR"
/locus_tag="ECOK1_0081"
/note="DNA-binding transcriptional regulator FruR;
Provisional; Region: PRK11303"
/db_xref="CDD:236897"
misc_feature 90398..90559
/gene="fruR"
/locus_tag="ECOK1_0081"
/note="Helix-turn-helix (HTH) DNA binding domain of the
LacI family of transcriptional regulators; Region:
HTH_LacI; cd01392"
/db_xref="CDD:143331"
misc_feature order(90419..90433,90437..90442,90449..90451,90473..90478,
90485..90487,90524..90526,90533..90535,90542..90547,
90551..90556)
/gene="fruR"
/locus_tag="ECOK1_0081"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:143331"
misc_feature 90524..90553
/gene="fruR"
/locus_tag="ECOK1_0081"
/note="domain linker motif; other site"
/db_xref="CDD:143331"
misc_feature 90572..91363
/gene="fruR"
/locus_tag="ECOK1_0081"
/note="Ligand binding domain of DNA transcription
repressor specific for fructose (FruR) and its close
homologs; Region: PBP1_FruR; cd06274"
/db_xref="CDD:107269"
misc_feature order(90596..90598,90626..90631,90635..90640,90647..90649,
90662..90664,90671..90673,90677..90679,90731..90733,
91136..91138,91226..91228,91232..91234)
/gene="fruR"
/locus_tag="ECOK1_0081"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:107269"
misc_feature order(90608..90610,90620..90622,90821..90826,90857..90868,
90974..90976,91121..91123,91205..91207)
/gene="fruR"
/locus_tag="ECOK1_0081"
/note="ligand binding site [chemical binding]; other site"
/db_xref="CDD:107269"
gene 91992..92450
/gene="mraZ"
/locus_tag="ECOK1_0082"
/db_xref="GeneID:12688650"
CDS 91992..92450
/gene="mraZ"
/locus_tag="ECOK1_0082"
/note="identified by similarity to GB:AAN78597.1; match to
protein family HMM PF02381; match to protein family HMM
TIGR00242"
/codon_start=1
/transl_table=11
/product="MraZ protein"
/protein_id="YP_006099337.1"
/db_xref="GI:386597831"
/db_xref="GeneID:12688650"
/translation="MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPC
LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
GLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL"
misc_feature 91992..92444
/gene="mraZ"
/locus_tag="ECOK1_0082"
/note="mraZ protein; Region: TIGR00242"
/db_xref="CDD:129345"
misc_feature 91992..92219
/gene="mraZ"
/locus_tag="ECOK1_0082"
/note="MraZ protein; Region: MraZ; pfam02381"
/db_xref="CDD:111290"
misc_feature 92220..92396
/gene="mraZ"
/locus_tag="ECOK1_0082"
/note="MraZ protein; Region: MraZ; pfam02381"
/db_xref="CDD:111290"
gene 92452..93393
/gene="mraW"
/locus_tag="ECOK1_0083"
/db_xref="GeneID:12688651"
CDS 92452..93393
/gene="mraW"
/locus_tag="ECOK1_0083"
/EC_number="2.1.1.-"
/note="identified by match to protein family HMM PF01795;
match to protein family HMM TIGR00006"
/codon_start=1
/transl_table=11
/product="S-adenosyl-methyltransferase MraW"
/protein_id="YP_006099338.1"
/db_xref="GI:386597832"
/db_xref="GeneID:12688651"
/translation="MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
LGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDL
GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
IEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKL
GGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA"
misc_feature 92461..93384
/gene="mraW"
/locus_tag="ECOK1_0083"
/note="16S rRNA (cytosine(1402)-N(4))-methyltransferase;
Region: TIGR00006"
/db_xref="CDD:232778"
misc_feature 92464..93387
/gene="mraW"
/locus_tag="ECOK1_0083"
/note="16S rRNA m(4)C1402 methyltranserfase; Provisional;
Region: PRK00050"
/db_xref="CDD:234597"
gene 93390..93755
/gene="ftsL"
/locus_tag="ECOK1_0084"
/db_xref="GeneID:12688652"
CDS 93390..93755
/gene="ftsL"
/locus_tag="ECOK1_0084"
/note="identified by similarity to SP:P22187; match to
protein family HMM PF04999; match to protein family HMM
TIGR02209"
/codon_start=1
/transl_table=11
/product="cell division protein FtsL"
/protein_id="YP_006099339.1"
/db_xref="GI:386597833"
/db_xref="GeneID:12688652"
/translation="MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFI
CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
EKLQMQHVDPSQENIVVQK"
misc_feature 93438..93752
/gene="ftsL"
/locus_tag="ECOK1_0084"
/note="cell division protein FtsL; Provisional; Region:
PRK10772"
/db_xref="CDD:182717"
gene 93771..95537
/gene="ftsI"
/locus_tag="ECOK1_0085"
/db_xref="GeneID:12688653"
CDS 93771..95537
/gene="ftsI"
/locus_tag="ECOK1_0085"
/EC_number="2.4.1.129"
/note="identified by similarity to SP:P0AD68; match to
protein family HMM PF00905; match to protein family HMM
PF03717"
/codon_start=1
/transl_table=11
/product="peptidoglycan synthetase FtsI"
/protein_id="YP_006099340.1"
/db_xref="GI:386597834"
/db_xref="GeneID:12688653"
/translation="MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAW
LQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
GISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
EDISSTDSQAAHNLTLSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
NSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTVPY
RINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLG
LVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVD
PPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYI
NKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPD
ALTTGDKNEFVINQGEGTGGRS"
misc_feature 93774..95507
/gene="ftsI"
/locus_tag="ECOK1_0085"
/note="peptidoglycan synthase FtsI; Provisional; Region:
PRK15105"
/db_xref="CDD:185060"
misc_feature 93981..94436
/gene="ftsI"
/locus_tag="ECOK1_0085"
/note="Penicillin-binding Protein dimerisation domain;
Region: PBP_dimer; pfam03717"
/db_xref="CDD:217689"
misc_feature 94548..95432
/gene="ftsI"
/locus_tag="ECOK1_0085"
/note="Penicillin binding protein transpeptidase domain;
Region: Transpeptidase; pfam00905"
/db_xref="CDD:216183"
gene 95524..97011
/gene="murE"
/locus_tag="ECOK1_0086"
/db_xref="GeneID:12688654"
CDS 95524..97011
/gene="murE"
/locus_tag="ECOK1_0086"
/EC_number="6.3.2.13"
/note="identified by similarity to SP:P22188; match to
protein family HMM PF01225; match to protein family HMM
PF02875; match to protein family HMM PF08245; match to
protein family HMM TIGR01085"
/codon_start=1
/transl_table=11
/product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
6-diaminopimelate ligase"
/protein_id="YP_006099341.1"
/db_xref="GI:386597835"
/db_xref="GeneID:12688654"
/translation="MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGH
QADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFY
HEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
SAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
EHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKA
TDVNYHDSGATIRFSSSWGDGEIESRLMGAFNVSNLLLALATLLALGYPLADLLKTAA
RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
GKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGYAKVMEGRAEAVTC
AVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA"
misc_feature 95524..97005
/gene="murE"
/locus_tag="ECOK1_0086"
/note="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
6-diaminopimelate ligase; Provisional; Region: murE;
PRK00139"
/db_xref="CDD:178894"
misc_feature 95596..95829
/gene="murE"
/locus_tag="ECOK1_0086"
/note="Mur ligase family, catalytic domain; Region:
Mur_ligase; pfam01225"
/db_xref="CDD:201670"
misc_feature 95896..96450
/gene="murE"
/locus_tag="ECOK1_0086"
/note="Mur ligase middle domain; Region: Mur_ligase_M;
pfam08245"
/db_xref="CDD:203888"
misc_feature 96538..96798
/gene="murE"
/locus_tag="ECOK1_0086"
/note="Mur ligase family, glutamate ligase domain; Region:
Mur_ligase_C; pfam02875"
/db_xref="CDD:202441"
gene 97008..98366
/gene="murF"
/locus_tag="ECOK1_0087"
/db_xref="GeneID:12688655"
CDS 97008..98366
/gene="murF"
/locus_tag="ECOK1_0087"
/EC_number="6.3.2.10"
/note="identified by similarity to SP:P11880; match to
protein family HMM PF01225; match to protein family HMM
PF02875; match to protein family HMM PF08245; match to
protein family HMM TIGR01143"
/codon_start=1
/transl_table=11
/product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
alanine ligase"
/protein_id="YP_006099342.1"
/db_xref="GI:386597836"
/db_xref="GeneID:12688655"
/translation="MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALK
GERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARV
VALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELG
ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMN
ADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP
LPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIKLAENQLLLDDSYN
ANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGIDCVLSVGK
QSHAISTASGVGEHFSDKTALIARLKSLIAEQQVITILVKGSRSAAMEEVVRALQENG
TC"
misc_feature 97008..98363
/gene="murF"
/locus_tag="ECOK1_0087"
/note="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine
ligase; Reviewed; Region: murF; PRK10773"
/db_xref="CDD:182718"
misc_feature 97086..97292
/gene="murF"
/locus_tag="ECOK1_0087"
/note="Mur ligase family, catalytic domain; Region:
Mur_ligase; pfam01225"
/db_xref="CDD:201670"
misc_feature 97323..97856
/gene="murF"
/locus_tag="ECOK1_0087"
/note="Mur ligase middle domain; Region: Mur_ligase_M;
pfam08245"
/db_xref="CDD:203888"
misc_feature 97944..98171
/gene="murF"
/locus_tag="ECOK1_0087"
/note="Mur ligase family, glutamate ligase domain; Region:
Mur_ligase_C; pfam02875"
/db_xref="CDD:202441"
gene 98360..99442
/gene="mraY"
/locus_tag="ECOK1_0088"
/db_xref="GeneID:12688656"
CDS 98360..99442
/gene="mraY"
/locus_tag="ECOK1_0088"
/EC_number="2.7.8.13"
/note="identified by match to protein family HMM PF00953;
match to protein family HMM TIGR00445"
/codon_start=1
/transl_table=11
/product="phospho-N-acetylmuramoyl-pentapeptide-
transferase"
/protein_id="YP_006099343.1"
/db_xref="GI:386597837"
/db_xref="GeneID:12688656"
/translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
IAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
VVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQL
VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWA
TGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
EPRVIVRFWIISLMLVLIGLATLKVR"
misc_feature 98405..99439
/gene="mraY"
/locus_tag="ECOK1_0088"
/note="phospho-N-acetylmuramoyl-pentapeptide-transferase;
Provisional; Region: mraY; PRK00108"
/db_xref="CDD:234638"
misc_feature 98540..99427
/gene="mraY"
/locus_tag="ECOK1_0088"
/note="Phospho-N-acetylmuramoyl-pentapeptide-transferase
(mraY) is an enzyme responsible for the formation of the
first lipid intermediate in the synthesis of bacterial
cell wall peptidoglycan. It catalyzes the formation of...;
Region: GT_MraY; cd06852"
/db_xref="CDD:133462"
misc_feature 98702..98707
/gene="mraY"
/locus_tag="ECOK1_0088"
/note="Mg++ binding site [ion binding]; other site"
/db_xref="CDD:133462"
misc_feature 99149..99160
/gene="mraY"
/locus_tag="ECOK1_0088"
/note="putative catalytic motif [active]"
/db_xref="CDD:133462"
misc_feature order(99308..99310,99326..99340)
/gene="mraY"
/locus_tag="ECOK1_0088"
/note="putative substrate binding site [chemical binding];
other site"
/db_xref="CDD:133462"
gene 99445..100761
/gene="murD"
/locus_tag="ECOK1_0089"
/db_xref="GeneID:12688657"
CDS 99445..100761
/gene="murD"
/locus_tag="ECOK1_0089"
/EC_number="6.3.2.9"
/note="identified by similarity to SP:P14900; match to
protein family HMM PF02875; match to protein family HMM
PF08245; match to protein family HMM TIGR01087"
/codon_start=1
/transl_table=11
/product="UDP-N-acetylmuramoylalanine--D-glutamate ligase"
/protein_id="YP_006099344.1"
/db_xref="GI:386597838"
/db_xref="GeneID:12688657"
/translation="MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGL
DKLPEAVERHTGGLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCRE
AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELS
SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALT
MPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
LALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWVNDSKATNVGSTEAALNGL
HVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETME
QAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG"
misc_feature 99445..100758
/gene="murD"
/locus_tag="ECOK1_0089"
/note="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
synthetase; Provisional; Region: murD; PRK03806"
/db_xref="CDD:179651"
misc_feature 99775..100254
/gene="murD"
/locus_tag="ECOK1_0089"
/note="Mur ligase middle domain; Region: Mur_ligase_M;
pfam08245"
/db_xref="CDD:203888"
misc_feature 100345..>100440
/gene="murD"
/locus_tag="ECOK1_0089"
/note="Mur ligase family, glutamate ligase domain; Region:
Mur_ligase_C; pfam02875"
/db_xref="CDD:202441"
gene 100761..102005
/gene="ftsW"
/locus_tag="ECOK1_0090"
/db_xref="GeneID:12688658"
CDS 100761..102005
/gene="ftsW"
/locus_tag="ECOK1_0090"
/note="identified by similarity to SP:P0ABG4; match to
protein family HMM PF01098; match to protein family HMM
TIGR02614"
/codon_start=1
/transl_table=11
/product="cell division protein FtsW"
/protein_id="YP_006099345.1"
/db_xref="GI:386597839"
/db_xref="GeneID:12688658"
/translation="MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMY
DRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRL
PMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
LWQFIAIIGMGISAVVLLILAEPYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGEL
WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVFFVAFRAMSIGRKAL
EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
MLLRIDYETRLEKAQAFVRGSR"
misc_feature 100791..102002
/gene="ftsW"
/locus_tag="ECOK1_0090"
/note="cell division protein FtsW; Provisional; Region:
PRK10774"
/db_xref="CDD:182719"
gene 102002..103069
/gene="murG"
/locus_tag="ECOK1_0091"
/db_xref="GeneID:12688659"
CDS 102002..103069
/gene="murG"
/locus_tag="ECOK1_0091"
/EC_number="2.4.1.227"
/note="identified by match to protein family HMM PF03033;
match to protein family HMM PF04101; match to protein
family HMM TIGR01133"
/codon_start=1
/transl_table=11
/product="undecaprenyldiphospho-muramoylpentapeptide
beta-N-acetylglucosaminyltransferase"
/protein_id="YP_006099346.1"
/db_xref="GI:386597840"
/db_xref="GeneID:12688659"
/translation="MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADR
MEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGM
GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQS
GKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPA
LFVPFQHKDRQQYWNALPLEKAGAAKIIEQSQLSVDAVANTLAGWSREILLTMAERAR
AASIPDATERVANEVSRAARA"
misc_feature 102017..103066
/gene="murG"
/locus_tag="ECOK1_0091"
/note="undecaprenyldiphospho-muramoylpentapeptide beta-N-
acetylglucosaminyltransferase; Provisional; Region: murG;
PRK00726"
/db_xref="CDD:179100"
misc_feature 102020..103045
/gene="murG"
/locus_tag="ECOK1_0091"
/note="MurG is an N-acetylglucosaminyltransferase, the
last enzyme involved in the intracellular phase of
peptidoglycan biosynthesis. It transfers
N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4
hydroxyl of a lipid-linked N-acetylmuramoyl
pentapeptide...; Region: GT1_MurG; cd03785"
/db_xref="CDD:99961"
misc_feature order(102050..102052,102380..102382,102572..102574,
102650..102652,102728..102730,102740..102742,
102785..102796,102803..102805,102842..102844,
102860..102865,102872..102874)
/gene="murG"
/locus_tag="ECOK1_0091"
/note="active site"
/db_xref="CDD:99961"
misc_feature order(102221..102223,102230..102232,102263..102265,
102347..102349,102422..102424)
/gene="murG"
/locus_tag="ECOK1_0091"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:99961"
gene 103123..104598
/gene="murC"
/locus_tag="ECOK1_0092"
/db_xref="GeneID:12688660"
CDS 103123..104598
/gene="murC"
/locus_tag="ECOK1_0092"
/EC_number="6.3.2.8"
/note="identified by match to protein family HMM PF01225;
match to protein family HMM PF02875; match to protein
family HMM PF08245; match to protein family HMM TIGR01082"
/codon_start=1
/transl_table=11
/product="UDP-N-acetylmuramate--L-alanine ligase"
/protein_id="YP_006099347.1"
/db_xref="GI:386597841"
/db_xref="GeneID:12688660"
/translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
QISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFL
HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
QDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEF
PLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYD
DFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEML
APVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD"
misc_feature 103159..104574
/gene="murC"
/locus_tag="ECOK1_0092"
/note="UDP-N-acetylmuramate--L-alanine ligase;
Provisional; Region: murC; PRK00421"
/db_xref="CDD:234757"
misc_feature 103183..103482
/gene="murC"
/locus_tag="ECOK1_0092"
/note="Mur ligase family, catalytic domain; Region:
Mur_ligase; pfam01225"
/db_xref="CDD:216373"
misc_feature 103498..103998
/gene="murC"
/locus_tag="ECOK1_0092"
/note="Mur ligase middle domain; Region: Mur_ligase_M;
pfam08245"
/db_xref="CDD:219763"
misc_feature 104128..104382
/gene="murC"
/locus_tag="ECOK1_0092"
/note="Mur ligase family, glutamate ligase domain; Region:
Mur_ligase_C; pfam02875"
/db_xref="CDD:217262"
gene 104591..105511
/gene="ddlB"
/locus_tag="ECOK1_0093"
/db_xref="GeneID:12688661"
CDS 104591..105511
/gene="ddlB"
/locus_tag="ECOK1_0093"
/EC_number="6.3.2.4"
/note="identified by similarity to SP:P07862; match to
protein family HMM PF01820; match to protein family HMM
PF07478; match to protein family HMM TIGR01205"
/codon_start=1
/transl_table=11
/product="D-alanine--D-alanine ligase"
/protein_id="YP_006099348.1"
/db_xref="GI:386597842"
/db_xref="GeneID:12688661"
/translation="MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE
VDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKL
LWQGAGLPVAPWVALTRAEFEKGLNDKQLAEISSLGLPVIVKPSREGSSVGMSKVVAE
NALQDALRLAFQHDEEVLIEKWLSGPEFTIAILGEEILPSIRIQPAGTFYDYEAKYLS
DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPG
MTSHSLVPMAARQAGMSFSQLVVRILELAD"
misc_feature 104591..105508
/gene="ddlB"
/locus_tag="ECOK1_0093"
/note="D-alanine--D-alanine ligase; Reviewed; Region: ddl;
PRK01372"
/db_xref="CDD:179288"
misc_feature 104600..104848
/gene="ddlB"
/locus_tag="ECOK1_0093"
/note="D-ala D-ala ligase N-terminus; Region:
Dala_Dala_lig_N; pfam01820"
/db_xref="CDD:201991"
misc_feature 104897..105499
/gene="ddlB"
/locus_tag="ECOK1_0093"
/note="D-ala D-ala ligase C-terminus; Region:
Dala_Dala_lig_C; pfam07478"
/db_xref="CDD:203643"
gene 105513..106343
/gene="ftsQ"
/locus_tag="ECOK1_0094"
/db_xref="GeneID:12688662"
CDS 105513..106343
/gene="ftsQ"
/locus_tag="ECOK1_0094"
/note="identified by similarity to SP:P06136; match to
protein family HMM PF03799; match to protein family HMM
PF08478"
/codon_start=1
/transl_table=11
/product="cell division protein FtsQ"
/protein_id="YP_006099349.1"
/db_xref="GI:386597843"
/db_xref="GeneID:12688662"
/translation="MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWV
VLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQR
LPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPDRTSKQVLPML
YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMK
RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
"
misc_feature 105513..106304
/gene="ftsQ"
/locus_tag="ECOK1_0094"
/note="cell division protein FtsQ; Provisional; Region:
PRK10775"
/db_xref="CDD:182720"
misc_feature 105681..105890
/gene="ftsQ"
/locus_tag="ECOK1_0094"
/note="POTRA domain, FtsQ-type; Region: POTRA_1;
pfam08478"
/db_xref="CDD:219857"
misc_feature 105897..106253
/gene="ftsQ"
/locus_tag="ECOK1_0094"
/note="Cell division protein FtsQ; Region: FtsQ;
pfam03799"
/db_xref="CDD:217736"
gene 106340..107602
/gene="ftsA"
/locus_tag="ECOK1_0095"
/db_xref="GeneID:12688663"
CDS 106340..107602
/gene="ftsA"
/locus_tag="ECOK1_0095"
/note="identified by similarity to SP:P0ABH0; match to
protein family HMM PF02491; match to protein family HMM
TIGR01174"
/codon_start=1
/transl_table=11
/product="cell division protein FtsA"
/protein_id="YP_006099350.1"
/db_xref="GI:386597844"
/db_xref="GeneID:12688663"
/translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDI
AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVL
TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
GEAEVEKRVTASVGSWIKRLNSWLRKEF"
misc_feature 106340..107599
/gene="ftsA"
/locus_tag="ECOK1_0095"
/note="cell division protein FtsA; Reviewed; Region: ftsA;
PRK09472"
/db_xref="CDD:181887"
misc_feature 106640..>107023
/gene="ftsA"
/locus_tag="ECOK1_0095"
/note="Nucleotide-Binding Domain of the sugar
kinase/HSP70/actin superfamily; Region:
NBD_sugar-kinase_HSP70_actin; cd00012"
/db_xref="CDD:212657"
misc_feature 106955..107416
/gene="ftsA"
/locus_tag="ECOK1_0095"
/note="Cell division protein FtsA; Region: FtsA;
pfam14450"
/db_xref="CDD:222760"
STS 106891..107127
/gene="ftsA"
/locus_tag="ECOK1_0095"
/standard_name="G34047"
/db_xref="UniSTS:10389"
gene 107663..108814
/gene="ftsZ"
/locus_tag="ECOK1_0096"
/db_xref="GeneID:12688664"
CDS 107663..108814
/gene="ftsZ"
/locus_tag="ECOK1_0096"
/note="identified by similarity to SP:P0A9A6; match to
protein family HMM PF00091; match to protein family HMM
PF03953; match to protein family HMM TIGR00065"
/codon_start=1
/transl_table=11
/product="cell division protein FtsZ"
/protein_id="YP_006099351.1"
/db_xref="GI:386597845"
/db_xref="GeneID:12688664"
/translation="MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAA
GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
VMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD"
misc_feature 107663..108811
/gene="ftsZ"
/locus_tag="ECOK1_0096"
/note="cell division protein FtsZ; Validated; Region:
PRK09330"
/db_xref="CDD:236468"
misc_feature 107732..108604
/gene="ftsZ"
/locus_tag="ECOK1_0096"
/note="FtsZ is a GTPase that is similar to the eukaryotic
tubulins and is essential for cell division in
prokaryotes. FtsZ is capable of polymerizing in a
GTP-driven process into structures similar to those formed
by tubulin. FtsZ forms a ring-shaped septum at...; Region:
FtsZ_type1; cd02201"
/db_xref="CDD:100021"
misc_feature order(107732..107734,107804..107806,107969..107989,
108062..108067,108086..108088,108155..108157,
108206..108208,108215..108220,108227..108229)
/gene="ftsZ"
/locus_tag="ECOK1_0096"
/note="nucleotide binding site [chemical binding]; other
site"
/db_xref="CDD:100021"
misc_feature order(108278..108283,108287..108289,108467..108478,
108485..108487)
/gene="ftsZ"
/locus_tag="ECOK1_0096"
/note="SulA interaction site; other site"
/db_xref="CDD:100021"
gene 108915..109832
/gene="lpxC"
/locus_tag="ECOK1_0097"
/db_xref="GeneID:12688665"
CDS 108915..109832
/gene="lpxC"
/locus_tag="ECOK1_0097"
/EC_number="3.5.1.-"
/note="identified by match to protein family HMM PF03331;
match to protein family HMM TIGR00325"
/codon_start=1
/transl_table=11
/product="UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
deacetylase"
/protein_id="YP_006099352.1"
/db_xref="GI:386597846"
/db_xref="GeneID:12688665"
/translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
IMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTID
FNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
AKQEAWEYVTFQDDAELPLAFKAPSAVLA"
misc_feature 108915..109811
/gene="lpxC"
/locus_tag="ECOK1_0097"
/note="UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
deacetylase; Reviewed; Region: lpxC; PRK13186"
/db_xref="CDD:237294"
misc_feature 108918..109754
/gene="lpxC"
/locus_tag="ECOK1_0097"
/note="UDP-3-O-acyl N-acetylglycosamine deacetylase;
Region: LpxC; pfam03331"
/db_xref="CDD:202596"
gene 109988..110575
/gene="secM"
/locus_tag="ECOK1_0098"
/db_xref="GeneID:12688666"
CDS 109988..110575
/gene="secM"
/locus_tag="ECOK1_0098"
/note="identified by similarity to SP:P62395; match to
protein family HMM PF06558"
/codon_start=1
/transl_table=11
/product="secretion monitor protein"
/protein_id="YP_006099353.1"
/db_xref="GI:386597847"
/db_xref="GeneID:12688666"
/translation="MLWTSGFNDKICALNTFEYDRDGNNVSGILTRWRQFGKRYFWPH
LLLGMVAASLGLPALSNAAEPNAPAKATTRNHEPSAKVNFGQLALLEANTRRPNSNYS
VDYWHQHAIRTVIRHLSFAMAPQTLPVAEESLPLQAQHLALLDTLSALLTQEGTPSEK
GYRIDYAHFTPQAKFSTPVWISQAQGIRAGPQRLS"
misc_feature 110066..110572
/gene="secM"
/locus_tag="ECOK1_0098"
/note="SecA regulator SecM; Provisional; Region: PRK02943"
/db_xref="CDD:235088"
gene 110637..113342
/gene="secA"
/locus_tag="ECOK1_0099"
/db_xref="GeneID:12688667"
CDS 110637..113342
/gene="secA"
/locus_tag="ECOK1_0099"
/note="identified by match to protein family HMM PF01043;
match to protein family HMM PF02810; match to protein
family HMM PF07516; match to protein family HMM PF07517;
match to protein family HMM TIGR00963"
/codon_start=1
/transl_table=11
/product="Preprotein translocase subunit SecA"
/protein_id="YP_006099354.1"
/db_xref="GI:386597848"
/db_xref="GeneID:12688667"
/translation="MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELK
GKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEM
RTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG
MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
ARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE
RGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
IVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTG
TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQ
PVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAG
RGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLAAGGLHIIGTERHESRR
IDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIRED
VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERIL
AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
PKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQ
LSYQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ"
misc_feature 110640..113339
/gene="secA"
/locus_tag="ECOK1_0099"
/note="preprotein translocase subunit SecA; Reviewed;
Region: PRK12904"
/db_xref="CDD:183826"
misc_feature 111318..111710
/gene="secA"
/locus_tag="ECOK1_0099"
/note="SecA preprotein cross-linking domain; Region:
SecA_PP_bind; smart00958"
/db_xref="CDD:198026"
misc_feature 111915..112397
/gene="secA"
/locus_tag="ECOK1_0099"
/note="Helicase superfamily c-terminal domain; associated
with DEXDc-, DEAD-, and DEAH-box proteins, yeast
initiation factor 4A, Ski2p, and Hepatitis C virus NS3
helicases; this domain is found in a wide variety of
helicases and helicase related proteins; may...; Region:
HELICc; cd00079"
/db_xref="CDD:28960"
misc_feature order(112005..112016,112074..112079,112146..112154)
/gene="secA"
/locus_tag="ECOK1_0099"
/note="nucleotide binding region [chemical binding]; other
site"
/db_xref="CDD:28960"
misc_feature order(112170..112172,112344..112346,112356..112358,
112365..112367)
/gene="secA"
/locus_tag="ECOK1_0099"
/note="ATP-binding site [chemical binding]; other site"
/db_xref="CDD:28960"
misc_feature 113277..113333
/gene="secA"
/locus_tag="ECOK1_0099"
/note="SEC-C motif; Region: SEC-C; pfam02810"
/db_xref="CDD:202406"
gene 113402..113800
/gene="mutT"
/locus_tag="ECOK1_0100"
/db_xref="GeneID:12688668"
CDS 113402..113800
/gene="mutT"
/locus_tag="ECOK1_0100"
/EC_number="3.6.1.-"
/note="identified by match to protein family HMM PF00293;
match to protein family HMM TIGR00586"
/codon_start=1
/transl_table=11
/product="7,8-dihydro-8-oxoguanine-triphosphatase"
/protein_id="YP_006099355.1"
/db_xref="GI:386597849"
/db_xref="GeneID:12688668"
/translation="MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKVEMGE
TPEQAVVRELQEEVGITPQHFSLFEKLEYEFPDRHITLWFWLVESWEGEPWGKEGQPG
EWMSLVGLNADDFPPANEPVIAKLKRVYAG"
misc_feature 113411..113782
/gene="mutT"
/locus_tag="ECOK1_0100"
/note="The MutT pyrophosphohydrolase is a prototypical
Nudix hydrolase that catalyzes the hydrolysis of
nucleoside and deoxynucleoside triphosphates (NTPs and
dNTPs) by substitution at a beta-phosphorus to yield a
nucleotide monophosphate (NMP) and inorganic...; Region:
MutT_pyrophosphohydrolase; cd03425"
/db_xref="CDD:72883"
misc_feature order(113411..113413,113417..113419,113513..113518,
113522..113524,113558..113560,113567..113572,
113639..113641,113693..113695,113756..113758)
/gene="mutT"
/locus_tag="ECOK1_0100"
/note="active site"
/db_xref="CDD:72883"
misc_feature order(113411..113413,113417..113419,113513..113518,
113633..113635,113639..113641,113756..113758)
/gene="mutT"
/locus_tag="ECOK1_0100"
/note="8-oxo-dGMP binding site [chemical binding]; other
site"
/db_xref="CDD:72883"
misc_feature 113513..113581
/gene="mutT"
/locus_tag="ECOK1_0100"
/note="nudix motif; other site"
/db_xref="CDD:72883"
misc_feature order(113558..113560,113567..113572)
/gene="mutT"
/locus_tag="ECOK1_0100"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:72883"
gene complement(113888..114085)
/locus_tag="ECOK1_0101"
/db_xref="GeneID:12688669"
CDS complement(113888..114085)
/locus_tag="ECOK1_0101"
/note="identified by similarity to SP:P0A8H8; match to
protein family HMM PF03884"
/codon_start=1
/transl_table=11
/product="zinc-binding protein YacG"
/protein_id="YP_006099356.1"
/db_xref="GI:386597850"
/db_xref="GeneID:12688669"
/translation="MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEE
KRIPSSGDLSESDDWSEEPKQ"
misc_feature complement(113900..114085)
/locus_tag="ECOK1_0101"
/note="DNA gyrase inhibitor; Reviewed; Region: PRK00418"
/db_xref="CDD:234754"
gene complement(114095..114838)
/locus_tag="ECOK1_0102"
/db_xref="GeneID:12688670"
CDS complement(114095..114838)
/locus_tag="ECOK1_0102"
/note="identified by match to protein family HMM PF07072"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099357.1"
/db_xref="GI:386597851"
/db_xref="GeneID:12688670"
/translation="MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFF
RNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVL
ISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIAS
LNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGH
KSRFAIRFMPLDSENGQVPERLDFELACC"
misc_feature complement(114098..114829)
/locus_tag="ECOK1_0102"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG4582"
/db_xref="CDD:226948"
gene complement(114838..115458)
/gene="coaE"
/locus_tag="ECOK1_0103"
/db_xref="GeneID:12688671"
CDS complement(114838..115458)
/gene="coaE"
/locus_tag="ECOK1_0103"
/EC_number="2.7.1.24"
/note="identified by match to protein family HMM PF01121;
match to protein family HMM TIGR00152"
/codon_start=1
/transl_table=11
/product="dephospho-CoA kinase"
/protein_id="YP_006099358.1"
/db_xref="GI:386597852"
/db_xref="GeneID:12688671"
/translation="MRYIVALTGGIGSGKSTVANAFANLGINVIDADIIARQVVEPGA
PALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQ
ATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
TREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP"
misc_feature complement(114886..115449)
/gene="coaE"
/locus_tag="ECOK1_0103"
/note="dephospho-CoA kinase; Region: TIGR00152"
/db_xref="CDD:129256"
misc_feature complement(114916..115449)
/gene="coaE"
/locus_tag="ECOK1_0103"
/note="Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24)
catalyzes the phosphorylation of dephosphocoenzyme A
(dCoA) to yield CoA, which is the final step in CoA
biosynthesis; Region: DPCK; cd02022"
/db_xref="CDD:30195"
misc_feature complement(order(114982..114984,115117..115122,
115192..115194,115360..115362,115435..115437))
/gene="coaE"
/locus_tag="ECOK1_0103"
/note="CoA-binding site [chemical binding]; other site"
/db_xref="CDD:30195"
misc_feature complement(order(114934..114936,115039..115041,
115414..115419,115426..115434))
/gene="coaE"
/locus_tag="ECOK1_0103"
/note="ATP-binding [chemical binding]; other site"
/db_xref="CDD:30195"
gene 115683..116726
/gene="guaC"
/locus_tag="ECOK1_0104"
/db_xref="GeneID:12688672"
CDS 115683..116726
/gene="guaC"
/locus_tag="ECOK1_0104"
/EC_number="1.7.1.7"
/note="identified by match to protein family HMM PF00478;
match to protein family HMM TIGR01305"
/codon_start=1
/transl_table=11
/product="guanosine monophosphate reductase"
/protein_id="YP_006099359.1"
/db_xref="GI:386597853"
/db_xref="GeneID:12688672"
/translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSW
SGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVS
TGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
DGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMK
RHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFI
RVQEQENRIFNNL"
misc_feature 115683..116720
/gene="guaC"
/locus_tag="ECOK1_0104"
/note="guanosine 5'-monophosphate oxidoreductase;
Provisional; Region: PRK05096"
/db_xref="CDD:235343"
misc_feature 115707..116690
/gene="guaC"
/locus_tag="ECOK1_0104"
/note="IMPDH: The catalytic domain of the inosine
monophosphate dehydrogenase. IMPDH catalyzes the
NAD-dependent oxidation of inosine 5'-monophosphate (IMP)
to xanthosine 5' monophosphate (XMP). It is a
rate-limiting step in the de novo synthesis of...; Region:
IMPDH; cd00381"
/db_xref="CDD:238223"
misc_feature order(115836..115838,116232..116240,116337..116339,
116343..116345,116406..116411,116478..116480,
116484..116492,116547..116552)
/gene="guaC"
/locus_tag="ECOK1_0104"
/note="active site"
/db_xref="CDD:238223"
gene complement(116761..117963)
/gene="pilC"
/locus_tag="ECOK1_0105"
/db_xref="GeneID:12688673"
CDS complement(116761..117963)
/gene="pilC"
/locus_tag="ECOK1_0105"
/note="identified by match to protein family HMM PF00482"
/codon_start=1
/transl_table=11
/product="type IV pilus assembly protein PilC"
/protein_id="YP_006099360.1"
/db_xref="GI:386597854"
/db_xref="GeneID:12688673"
/translation="MASKQLWRWHGITGDGNAQDGMLWAESRALLLMALQQQMVTPLS
LKRITINSTQWRGDISAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAH
DLEQGVAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVK
SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLASFSGEWGW
LLVLFGFLLAIANKLLMRHPTRLIARQKLLLRIPIMGSLMRGQKLTQIFTILTLTQSA
GISFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNAGEFSPLCLQLVRTG
EASGSLDLMLDNLAHHHRDNTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHL
GDAMSGMG"
misc_feature complement(116773..117963)
/gene="pilC"
/locus_tag="ECOK1_0105"
/note="type IV pilin biogenesis protein; Provisional;
Region: PRK10573"
/db_xref="CDD:182559"
misc_feature complement(117466..117774)
/gene="pilC"
/locus_tag="ECOK1_0105"
/note="Type II secretion system (T2SS), protein F; Region:
T2SF; pfam00482"
/db_xref="CDD:201255"
misc_feature complement(<116896..117141)
/gene="pilC"
/locus_tag="ECOK1_0105"
/note="Type II secretion system (T2SS), protein F; Region:
T2SF; pfam00482"
/db_xref="CDD:201255"
gene complement(117953..119338)
/gene="hofB"
/locus_tag="ECOK1_0106"
/db_xref="GeneID:12688674"
CDS complement(117953..119338)
/gene="hofB"
/locus_tag="ECOK1_0106"
/note="identified by match to protein family HMM PF00437"
/codon_start=1
/transl_table=11
/product="GspE family protein HofB"
/protein_id="YP_006099361.1"
/db_xref="GI:386597855"
/db_xref="GeneID:12688674"
/translation="MNIPQLTALCLRYQGVLLDASEEVVHVAVVDAPSHELLDALHFA
TTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQPKAELLTRTLQSALEQRASDIHI
EPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVEL
AGNAVSFRIATLACRGGEKVVLRLLQQVNQALDVNTLGMQPSQLVDFAHALQQPQGLV
LVTGPTGSGKTVTLYSALQMLNTADINICSVEDPVEIPIAGLNQTQIHSRAGLTFQGV
LRALLRQDPDVIMIGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTCETLVRLQQMGVA
RWMLSSALTLVIAQRLVRKLCPHCRRQQGEPIHIPDNVWPSPLPHWQAPGCVHCYHGF
YGRTALFEVLPITPVIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEE
LIRVLGMPHGE"
misc_feature complement(117962..119338)
/gene="hofB"
/locus_tag="ECOK1_0106"
/note="hypothetical protein; Provisional; Region:
PRK10436"
/db_xref="CDD:236694"
misc_feature complement(118154..118933)
/gene="hofB"
/locus_tag="ECOK1_0106"
/note="PulE/GspE The type II secretory pathway is the main
terminal branch of the general secretory pathway (GSP).
It is responsible for the export the majority of
Gram-negative bacterial exoenzymes and toxins. PulE is a
cytoplasmic protein of the GSP, which...; Region:
PulE-GspE; cd01129"
/db_xref="CDD:238549"
misc_feature complement(118652..118675)
/gene="hofB"
/locus_tag="ECOK1_0106"
/note="Walker A motif; other site"
/db_xref="CDD:238549"
misc_feature complement(order(118463..118468,118586..118591,
118595..118597,118652..118660,118670..118672))
/gene="hofB"
/locus_tag="ECOK1_0106"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:238549"
misc_feature complement(118463..118480)
/gene="hofB"
/locus_tag="ECOK1_0106"
/note="Walker B motif; other site"
/db_xref="CDD:238549"
gene complement(119348..119788)
/gene="pilA"
/locus_tag="ECOK1_0107"
/db_xref="GeneID:12688675"
CDS complement(119348..119788)
/gene="pilA"
/locus_tag="ECOK1_0107"
/note="gene synonym: ppdD; identified by similarity to
GB:AAX12396.1; match to protein family HMM PF07963; match
to protein family HMM TIGR02532"
/codon_start=1
/transl_table=11
/product="type 4 pilus subunit PilA"
/protein_id="YP_006099362.1"
/db_xref="GI:386597856"
/db_xref="GeneID:12688675"
/translation="MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
TFVPYRTAVELCALEHGGLNTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNG
LSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN"
misc_feature complement(119351..119788)
/gene="pilA"
/locus_tag="ECOK1_0107"
/note="putative major pilin subunit; Provisional; Region:
PRK10574"
/db_xref="CDD:182560"
misc_feature complement(<119744..>119782)
/gene="pilA"
/locus_tag="ECOK1_0107"
/note="Type IV pilin N-term methylation site GFxxxE;
Region: N_methyl_2; pfam13544"
/db_xref="CDD:205722"
misc_feature complement(119426..119641)
/gene="pilA"
/locus_tag="ECOK1_0107"
/note="Pilin (bacterial filament); Region: Pilin;
pfam00114"
/db_xref="CDD:201012"
gene complement(119992..120885)
/gene="nadC"
/locus_tag="ECOK1_0108"
/db_xref="GeneID:12688676"
CDS complement(119992..120885)
/gene="nadC"
/locus_tag="ECOK1_0108"
/EC_number="2.4.2.19"
/note="identified by similarity to SP:P30011; match to
protein family HMM PF01729; match to protein family HMM
PF02749; match to protein family HMM TIGR00078"
/codon_start=1
/transl_table=11
/product="nicotinate-nucleotide diphosphorylase"
/protein_id="YP_006099363.1"
/db_xref="GI:386597857"
/db_xref="GeneID:12688676"
/translation="MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANND
ITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQ
PLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVEN
LEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVD
FISVGALTKHVQALDLSMRFR"
misc_feature complement(119995..120885)
/gene="nadC"
/locus_tag="ECOK1_0108"
/note="quinolinate phosphoribosyltransferase; Validated;
Region: PRK09016"
/db_xref="CDD:181612"
misc_feature complement(120001..120810)
/gene="nadC"
/locus_tag="ECOK1_0108"
/note="Quinolinate phosphoribosyl transferase (QAPRTase or
QPRTase), also called nicotinate-nucleotide
pyrophosphorylase, is involved in the de novo synthesis of
NAD in both prokaryotes and eukaryotes. It catalyses the
reaction of quinolinic acid (QA) with...; Region: QPRTase;
cd01572"
/db_xref="CDD:238806"
misc_feature complement(order(120031..120033,120277..120279,
120310..120312,120319..120324,120328..120330,
120334..120336,120346..120351,120406..120411,
120421..120423,120427..120429,120517..120519,
120529..120534,120745..120750))
/gene="nadC"
/locus_tag="ECOK1_0108"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:238806"
misc_feature complement(order(120031..120033,120040..120045,
120049..120051,120106..120111,120178..120180,
120358..120363,120424..120432))
/gene="nadC"
/locus_tag="ECOK1_0108"
/note="active site"
/db_xref="CDD:238806"
gene 120973..121524
/gene="ampD"
/locus_tag="ECOK1_0109"
/db_xref="GeneID:12688677"
CDS 120973..121524
/gene="ampD"
/locus_tag="ECOK1_0109"
/EC_number="3.5.1.28"
/note="identified by similarity to SP:P13016; match to
protein family HMM PF01510"
/codon_start=1
/transl_table=11
/product="N-acetylmuramoyl-L-alanine amidase"
/protein_id="YP_006099364.1"
/db_xref="GI:386597858"
/db_xref="GeneID:12688677"
/translation="MLLEQGWLAGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFG
GPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQY
QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDRYPDIANNMTGHCDIAPD
RKTDPGPAFDWARFRALVSKETT"
misc_feature 120979..>121506
/gene="ampD"
/locus_tag="ECOK1_0109"
/note="N-acetyl-anhydromuramyl-L-alanine amidase [Cell
envelope biogenesis, outer membrane]; Region: ampD;
COG3023"
/db_xref="CDD:32839"
misc_feature 121054..121476
/gene="ampD"
/locus_tag="ECOK1_0109"
/note="Peptidoglycan recognition proteins (PGRPs) are
pattern recognition receptors that bind, and in certain
cases, hydrolyze peptidoglycans (PGNs) of bacterial cell
walls. PGRPs have been divided into three classes: short
PGRPs (PGRP-S), that are small (20...; Region: PGRP;
cd06583"
/db_xref="CDD:133475"
misc_feature order(121072..121074,121192..121194,121432..121434,
121456..121458,121462..121464)
/gene="ampD"
/locus_tag="ECOK1_0109"
/note="amidase catalytic site [active]"
/db_xref="CDD:133475"
misc_feature order(121072..121074,121432..121434,121462..121464)
/gene="ampD"
/locus_tag="ECOK1_0109"
/note="Zn binding residues [ion binding]; other site"
/db_xref="CDD:133475"
misc_feature order(121075..121080,121150..121152,121192..121194,
121234..121236,121255..121260,121297..121299,
121432..121434,121444..121446,121456..121464)
/gene="ampD"
/locus_tag="ECOK1_0109"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:133475"
gene 121521..122375
/gene="ampE"
/locus_tag="ECOK1_0110"
/db_xref="GeneID:12688678"
CDS 121521..122375
/gene="ampE"
/locus_tag="ECOK1_0110"
/note="identified by similarity to SP:P0AE15"
/codon_start=1
/transl_table=11
/product="protein AmpE"
/protein_id="YP_006099365.1"
/db_xref="GI:386597859"
/db_xref="GeneID:12688678"
/translation="MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTL
CMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRND
SHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKAL
PAWFASLGDFHTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIAL
LTIYGALV"
misc_feature 121521..122372
/gene="ampE"
/locus_tag="ECOK1_0110"
/note="regulatory protein AmpE; Provisional; Region:
PRK10987"
/db_xref="CDD:182884"
gene complement(122418..123788)
/gene="aroP"
/locus_tag="ECOK1_0111"
/db_xref="GeneID:12688679"
CDS complement(122418..123788)
/gene="aroP"
/locus_tag="ECOK1_0111"
/note="identified by similarity to SP:P15993; match to
protein family HMM PF00324"
/codon_start=1
/transl_table=11
/product="aromatic amino acid transport protein AroP"
/protein_id="YP_006099366.1"
/db_xref="GI:386597860"
/db_xref="GeneID:12688679"
/translation="MEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAG
PGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVLY
VLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKV
IAVVAMIIFGAWLLFSGNGGPQASVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLEL
VGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFH
ELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPVN
TILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQGV
VTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKTA
KAVKAH"
misc_feature complement(122421..123788)
/gene="aroP"
/locus_tag="ECOK1_0111"
/note="aromatic amino acid transporter; Provisional;
Region: PRK10238"
/db_xref="CDD:182324"
misc_feature complement(122520..>123179)
/gene="aroP"
/locus_tag="ECOK1_0111"
/note="Spore germination protein; Region: Spore_permease;
cl15802"
/db_xref="CDD:210202"
gene 124316..126097
/locus_tag="ECOK1_0112"
/db_xref="GeneID:12688680"
CDS 124316..126097
/locus_tag="ECOK1_0112"
/note="identified by match to protein family HMM PF01844;
match to protein family HMM PF05638; match to protein
family HMM PF06958; match to protein family HMM TIGR03344"
/codon_start=1
/transl_table=11
/product="S-type pyocin family protein"
/protein_id="YP_006099367.1"
/db_xref="GI:386597861"
/db_xref="GeneID:12688680"
/translation="MGDIVYLRIIGEKQGDISSGCGTYASVGNRWQVGHEDEIFAFAL
TNAITSTGKGVNLQGLQFCKLIDKSSPLLSNAINQNERLFIEIDLYRINKSGRWERYY
YIQLRNASLTAIHVNISDNNLPTECVNVNYDYILCKHLIANTEFDWLAFPAGYNSLFI
PPKNPPASNLNPEPLPVVNLPLSPPAVKPVYAKSCLKEKGCTDAGTAEEPAENFGQVA
IFALPVVDDCCGYHHPEANDVGQPAEAQTMLLFPGSVLAAQIWGKWSLSGILSATCGS
YIGALASALYIPSAGEGSARVPGRDEFWYEEELRQKALAGSTATTRVRFFWGTDIHGK
PQVYGVHTGEGTPYENVRVANMQWNEQTQRYEFTPAHDVDGPLITWTPENPEHGYVPG
HTGNDRPPLEQPTILVTPIPDGTDTYTTPPFPVPDPKEFNDYILVFPAGSGIKPIYVY
LKEDPRKLPGVVTGRGVPLSPGTRWLDMSVSNNGNGAPIPAHIADKLRGREFKTFDEF
REALWLEVSQDPELIAQFSSGNQTRIKQGLTAKAPIDGWYYGPKEIVKKFQIHHRVAV
EYGGSVYDIDNLRIVTPRLHDEIHYRR"
misc_feature 124325..124759
/locus_tag="ECOK1_0112"
/note="Protein of unknown function (DUF796); Region:
DUF796; cl01226"
/db_xref="CDD:214110"
misc_feature 125240..125665
/locus_tag="ECOK1_0112"
/note="S-type Pyocin; Region: Pyocin_S; pfam06958"
/db_xref="CDD:191651"
misc_feature <125951..126085
/locus_tag="ECOK1_0112"
/note="HNH nucleases; HNH endonuclease signature which is
found in viral, prokaryotic, and eukaryotic proteins. The
alignment includes members of the large group of homing
endonucleases, yeast intron 1 protein, MutS, as well as
bacterial colicins, pyocins, and...; Region: HNHc;
cd00085"
/db_xref="CDD:28969"
misc_feature order(125990..125992,125996..126004,126008..126010,
126044..126049,126059..126064,126071..126073,
126083..126085)
/locus_tag="ECOK1_0112"
/note="active site"
/db_xref="CDD:28969"
gene 126792..127082
/locus_tag="ECOK1_0113"
/db_xref="GeneID:12688681"
CDS 126792..127082
/locus_tag="ECOK1_0113"
/note="identified by similarity to SP:P09881; match to
protein family HMM PF01320"
/codon_start=1
/transl_table=11
/product="colicin immunity protein"
/protein_id="YP_006099368.1"
/db_xref="GI:386597862"
/db_xref="GeneID:12688681"
/translation="MYNFKDEIEDYTEREFIELLGEFTNPTGDNAQLKGEELDKYWDD
LEEHLTRITQHPLMSDLIYYPAKKGDDEPENILKIVKEWRRSQGLPLFKDSK"
misc_feature 126795..127073
/locus_tag="ECOK1_0113"
/note="Colicin immunity protein / pyocin immunity protein;
Region: Colicin_Pyocin; pfam01320"
/db_xref="CDD:201726"
gene 127491..127781
/locus_tag="ECOK1_0114"
/db_xref="GeneID:12688682"
CDS 127491..127781
/locus_tag="ECOK1_0114"
/note="identified by similarity to SP:P09881; match to
protein family HMM PF01320"
/codon_start=1
/transl_table=11
/product="colicin immunity protein"
/protein_id="YP_006099369.1"
/db_xref="GI:386597863"
/db_xref="GeneID:12688682"
/translation="MHDLKYKIYFYTEGEFLEMLEEIVNATSKDKSLKGKKLEKYLDT
LVDHFIKITEHPKKGDLIFYPNSPEDGKPENILKIVKEWRRSQGLPLFKDSE"
misc_feature 127497..127772
/locus_tag="ECOK1_0114"
/note="Colicin immunity protein / pyocin immunity protein;
Region: Colicin_Pyocin; pfam01320"
/db_xref="CDD:201726"
gene 128237..129001
/locus_tag="ECOK1_0115"
/db_xref="GeneID:12688683"
CDS 128237..129001
/locus_tag="ECOK1_0115"
/note="identified by match to protein family HMM PF00392;
match to protein family HMM PF07729"
/codon_start=1
/transl_table=11
/product="GntR family transcriptional regulator"
/protein_id="YP_006099370.1"
/db_xref="GI:386597864"
/db_xref="GeneID:12688683"
/translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLE
TRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEA
AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAR
EASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN"
misc_feature 128237..128920
/locus_tag="ECOK1_0115"
/note="Transcriptional regulators [Transcription]; Region:
FadR; COG2186"
/db_xref="CDD:225097"
misc_feature 128264..128458
/locus_tag="ECOK1_0115"
/note="Winged helix-turn-helix (WHTH) DNA-binding domain
of the GntR family of transcriptional regulators; Region:
WHTH_GntR; cd07377"
/db_xref="CDD:153418"
misc_feature order(128264..128266,128270..128272,128339..128341,
128345..128350,128372..128386,128390..128395,
128402..128404,128432..128437,128441..128452)
/locus_tag="ECOK1_0115"
/note="DNA-binding site [nucleotide binding]; DNA binding
site"
/db_xref="CDD:153418"
misc_feature 128531..128914
/locus_tag="ECOK1_0115"
/note="This entry represents the C-terminal ligand binding
domain of many members of the GntR family; Region: FCD;
smart00895"
/db_xref="CDD:214892"
gene 129162..131825
/gene="aceE"
/locus_tag="ECOK1_0116"
/db_xref="GeneID:12688684"
CDS 129162..131825
/gene="aceE"
/locus_tag="ECOK1_0116"
/EC_number="1.2.4.1"
/note="identified by match to protein family HMM
TIGR00759"
/codon_start=1
/transl_table=11
/product="pyruvate dehydrogenase (acetyl-transferring),
homodimeric type"
/protein_id="YP_006099371.1"
/db_xref="GI:386597865"
/db_xref="GeneID:12688684"
/translation="MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEA
RKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKII
NELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTI
KGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHT
YLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLK
NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
QEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFL
IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
QENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETLEGSKGKVQLLGSGSILRHVR
EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
LAKRGEIDKKVVADAIAKFNIDADKVNPRLA"
misc_feature 129162..131822
/gene="aceE"
/locus_tag="ECOK1_0116"
/note="pyruvate dehydrogenase subunit E1; Reviewed;
Region: aceE; PRK09405"
/db_xref="CDD:236500"
misc_feature 129387..130544
/gene="aceE"
/locus_tag="ECOK1_0116"
/note="Thiamine pyrophosphate (TPP) family, E1 of E. coli
PDC-like subfamily, TPP-binding module; composed of
proteins similar to the E1 component of the Escherichia
coli pyruvate dehydrogenase multienzyme complex (PDC). PDC
catalyzes the oxidative...; Region: TPP_E1_EcPDC_like;
cd02017"
/db_xref="CDD:238975"
misc_feature order(129465..129473,129660..129671,129690..129695,
129699..129701,129705..129707,129732..129734,
129738..129746,129864..129875,129882..129884,
129891..129893,129903..129905,129951..129959,
129969..129971,129993..129995,130002..130007,
130014..130016)
/gene="aceE"
/locus_tag="ECOK1_0116"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:238975"
misc_feature order(129489..129491,129582..129584,129588..129590,
129738..129740,129744..129746,129852..129860,
129867..129869,129942..129944,129948..129950,
130338..130340)
/gene="aceE"
/locus_tag="ECOK1_0116"
/note="TPP-binding site [chemical binding]; other site"
/db_xref="CDD:238975"
gene 131840..133732
/gene="aceF"
/locus_tag="ECOK1_0117"
/db_xref="GeneID:12688685"
CDS 131840..133732
/gene="aceF"
/locus_tag="ECOK1_0117"
/EC_number="2.3.1.12"
/note="identified by similarity to SP:P06959; match to
protein family HMM PF00198; match to protein family HMM
PF00364; match to protein family HMM PF02817; match to
protein family HMM TIGR01348"
/codon_start=1
/transl_table=11
/product="dihydrolipoyllysine-residue acetyltransferase"
/protein_id="YP_006099372.1"
/db_xref="GI:386597866"
/db_xref="GeneID:12688685"
/translation="MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASM
EVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAA
AAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
KVNVGDKVSTGSLIMVFEVAGEAGAVAPAAKQEAAPAAAPASAAGVKEVNVPDIGGDE
VEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIM
IFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIR
RLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKV
DFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAK
RKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVV
PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVN
APEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSD
IRRLVM"
misc_feature 131840..133729
/gene="aceF"
/locus_tag="ECOK1_0117"
/note="pyruvate dehydrogenase dihydrolipoyltransacetylase;
Validated; Region: aceF; PRK11854"
/db_xref="CDD:183337"
misc_feature 131846..132061
/gene="aceF"
/locus_tag="ECOK1_0117"
/note="Lipoyl domain of the dihydrolipoyl acyltransferase
component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid
dehydrogenase multienzyme complexes, like pyruvate
dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH)
and branched-chain 2-oxo acid...; Region: lipoyl_domain;
cd06849"
/db_xref="CDD:133458"
misc_feature order(131930..131932,131951..131968,131978..131980)
/gene="aceF"
/locus_tag="ECOK1_0117"
/note="E3 interaction surface; other site"
/db_xref="CDD:133458"
misc_feature 131960..131962
/gene="aceF"
/locus_tag="ECOK1_0117"
/note="lipoyl attachment site [posttranslational
modification]; other site"
/db_xref="CDD:133458"
misc_feature 132161..132370
/gene="aceF"
/locus_tag="ECOK1_0117"
/note="Lipoyl domain of the dihydrolipoyl acyltransferase
component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid
dehydrogenase multienzyme complexes, like pyruvate
dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH)
and branched-chain 2-oxo acid...; Region: lipoyl_domain;
cd06849"
/db_xref="CDD:133458"
misc_feature order(132239..132241,132260..132277,132287..132289)
/gene="aceF"
/locus_tag="ECOK1_0117"
/note="E3 interaction surface; other site"
/db_xref="CDD:133458"
misc_feature 132269..132271
/gene="aceF"
/locus_tag="ECOK1_0117"
/note="lipoyl attachment site [posttranslational
modification]; other site"
/db_xref="CDD:133458"
misc_feature 132458..132673
/gene="aceF"
/locus_tag="ECOK1_0117"
/note="Lipoyl domain of the dihydrolipoyl acyltransferase
component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid
dehydrogenase multienzyme complexes, like pyruvate
dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH)
and branched-chain 2-oxo acid...; Region: lipoyl_domain;
cd06849"
/db_xref="CDD:133458"
misc_feature order(132542..132544,132563..132580,132590..132592)
/gene="aceF"
/locus_tag="ECOK1_0117"
/note="E3 interaction surface; other site"
/db_xref="CDD:133458"
misc_feature 132572..132574
/gene="aceF"
/locus_tag="ECOK1_0117"
/note="lipoyl attachment site [posttranslational
modification]; other site"
/db_xref="CDD:133458"
misc_feature 132818..132928
/gene="aceF"
/locus_tag="ECOK1_0117"
/note="e3 binding domain; Region: E3_binding; pfam02817"
/db_xref="CDD:202412"
misc_feature 133085..133729
/gene="aceF"
/locus_tag="ECOK1_0117"
/note="2-oxoacid dehydrogenases acyltransferase (catalytic
domain); Region: 2-oxoacid_dh; pfam00198"
/db_xref="CDD:201074"
gene 133940..135364
/gene="lpdA"
/locus_tag="ECOK1_0118"
/db_xref="GeneID:12688686"
CDS 133940..135364
/gene="lpdA"
/locus_tag="ECOK1_0118"
/EC_number="1.8.1.4"
/note="identified by match to protein family HMM PF00070;
match to protein family HMM PF01134; match to protein
family HMM PF02852; match to protein family HMM PF07992;
match to protein family HMM TIGR01350"
/codon_start=1
/transl_table=11
/product="dihydrolipoamide dehydrogenase"
/protein_id="YP_006099373.1"
/db_xref="GI:386597867"
/db_xref="GeneID:12688686"
/translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLA
GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
RIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDI
VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPN
GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
SVGLAAEVFEGSITDLPNPKAKKK"
misc_feature 133946..135355
/gene="lpdA"
/locus_tag="ECOK1_0118"
/note="dihydrolipoamide dehydrogenase; Reviewed; Region:
PRK06467"
/db_xref="CDD:180579"
misc_feature 133970..>134074
/gene="lpdA"
/locus_tag="ECOK1_0118"
/note="NAD(P)-binding Rossmann-like domain; Region:
NAD_binding_8; pfam13450"
/db_xref="CDD:205628"
misc_feature 134468..134707
/gene="lpdA"
/locus_tag="ECOK1_0118"
/note="Pyridine nucleotide-disulphide oxidoreductase;
Region: Pyr_redox; pfam00070"
/db_xref="CDD:215691"
misc_feature 134978..135307
/gene="lpdA"
/locus_tag="ECOK1_0118"
/note="Pyridine nucleotide-disulphide oxidoreductase,
dimerisation domain; Region: Pyr_redox_dim; pfam02852"
/db_xref="CDD:217252"
gene complement(135606..137363)
/locus_tag="ECOK1_0119"
/db_xref="GeneID:12688687"
CDS complement(135606..137363)
/locus_tag="ECOK1_0119"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099374.1"
/db_xref="GI:386597868"
/db_xref="GeneID:12688687"
/translation="MKMTLPFKPHVLALICSAGLCAASAGLYIKSRTVEAPVEAQSTQ
QTAPDISAVTLPATVSAPPVTPAVVKSAFSTAQIDQWVAPVALYPDSLLSQVLMASTY
PANVAQAVQWSHDNPLKQGDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNL
GDAFLAQPQDVMDSVQRLRQLAQQTGSLKSSTEQKIIATTKKVVPVNQPANAPATQSN
TVSTSSPVVAEPAPTVITIEPANPDVVYIPNYNPNVVYGSWANTAYPPVYLPPPAGEP
FVDSFVRGFGYSMGVATTYALFSSIDWDDDDHDHHHHDDDDYHHHDGGHRDGNDWQHN
GDNINIDVNNFNRITGEHLTDKNMAWRHNPNYRNGVTYHDQDMAKRFHQTDVNGGMSA
TQLPAPTRDSQRHAAASQFQQRTHAAPVITRDTQRQAAAQRFNEAEHYGSYDDFRDFS
RRQPLTQQQKDAARQRYQSASPEQRQAVREKIQANPQNQQRREAARQRIQSASPEQRQ
AVREKMQTNPQNQQQRDAARQRIQSASPEQRQVFREKVQESRPQRLNDSNHTARLNNE
QRSAVRERLSERGARRLER"
misc_feature complement(136275..137147)
/locus_tag="ECOK1_0119"
/note="Protein of unknown function (DUF3300); Region:
DUF3300; pfam11737"
/db_xref="CDD:152173"
gene 137718..140315
/gene="acnB"
/locus_tag="ECOK1_0120"
/db_xref="GeneID:12688688"
CDS 137718..140315
/gene="acnB"
/locus_tag="ECOK1_0120"
/EC_number="4.2.1.3"
/note="identified by match to protein family HMM PF00330;
match to protein family HMM PF06434; match to protein
family HMM TIGR00117"
/codon_start=1
/transl_table=11
/product="aconitate hydratase 2"
/protein_id="YP_006099375.1"
/db_xref="GI:386597869"
/db_xref="GeneID:12688688"
/translation="MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEF
LLDLLTNRVPPGVDEAAYVKAGFLAAVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPL
IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRP
ALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVG
PIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGG
KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDV
LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRA
CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
PVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNI
VLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPIL
CAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPP
TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
TGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFDQLSQYTEKA
DGVIFQTAV"
misc_feature 137718..140255
/gene="acnB"
/locus_tag="ECOK1_0120"
/note="bifunctional aconitate hydratase
2/2-methylisocitrate dehydratase; Validated; Region:
PRK09238"
/db_xref="CDD:236424"
misc_feature 138228..138650
/gene="acnB"
/locus_tag="ECOK1_0120"
/note="Aconitase B swivel domain. Aconitate hydratase B is
involved in energy metabolism as part of the TCA cycle. It
catalyses the formation of cis-aconitate from citrate.
This is the aconitase swivel domain, which undergoes
swivelling conformational change in...; Region:
AcnB_Swivel; cd01576"
/db_xref="CDD:238808"
misc_feature 138447..138455
/gene="acnB"
/locus_tag="ECOK1_0120"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:238808"
misc_feature 138867..140177
/gene="acnB"
/locus_tag="ECOK1_0120"
/note="Aconitate hydratase B catalyses the formation of
cis-aconitate from citrate as part of the TCA cycle;
Region: AcnB; cd01581"
/db_xref="CDD:153131"
misc_feature order(138957..138959,138966..138968,139206..139211,
140034..140036,140088..140090,140103..140105)
/gene="acnB"
/locus_tag="ECOK1_0120"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:153131"
misc_feature order(139212..139214,139845..139847,140022..140024,
140031..140036,140085..140087)
/gene="acnB"
/locus_tag="ECOK1_0120"
/note="ligand binding site [chemical binding]; other site"
/db_xref="CDD:153131"
gene 140490..140852
/locus_tag="ECOK1_0121"
/db_xref="GeneID:12688689"
CDS 140490..140852
/locus_tag="ECOK1_0121"
/note="identified by similarity to SP:P59396; match to
protein family HMM PF06062"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099376.1"
/db_xref="GI:386597870"
/db_xref="GeneID:12688689"
/translation="MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQ
AAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCG
VEDFLQVVAAYRNFVQQK"
misc_feature 140490..140849
/locus_tag="ECOK1_0121"
/note="hypothetical protein; Provisional; Region:
PRK05248"
/db_xref="CDD:235372"
gene complement(140890..141684)
/gene="speD"
/locus_tag="ECOK1_0122"
/db_xref="GeneID:12688690"
CDS complement(140890..141684)
/gene="speD"
/locus_tag="ECOK1_0122"
/EC_number="4.1.1.50"
/note="identified by match to protein family HMM PF02675;
match to protein family HMM TIGR03331"
/codon_start=1
/transl_table=11
/product="S-adenosylmethionine decarboxylase"
/protein_id="YP_006099377.1"
/db_xref="GI:386597871"
/db_xref="GeneID:12688690"
/translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTTEERDGYIAYIDELYN
ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLP
ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSEDMKALYDMVDVNVYQENIFHTKML
LKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV"
misc_feature complement(140893..141684)
/gene="speD"
/locus_tag="ECOK1_0122"
/note="S-adenosylmethionine decarboxylase; Provisional;
Region: PRK05462"
/db_xref="CDD:180099"
gene complement(141700..142566)
/gene="speE"
/locus_tag="ECOK1_0123"
/db_xref="GeneID:12688691"
CDS complement(141700..142566)
/gene="speE"
/locus_tag="ECOK1_0123"
/EC_number="2.5.1.16"
/note="identified by match to protein family HMM PF01564;
match to protein family HMM TIGR00417"
/codon_start=1
/transl_table=11
/product="spermidine synthase"
/protein_id="YP_006099378.1"
/db_xref="GI:386597872"
/db_xref="GeneID:12688691"
/translation="MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
SITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTNQTFDVIISDCT
DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGF
YQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAVHTAAFALP
QYLQDALASQPS"
misc_feature complement(141715..142548)
/gene="speE"
/locus_tag="ECOK1_0123"
/note="spermidine synthase; Provisional; Region: PRK00811"
/db_xref="CDD:179134"
misc_feature complement(141994..142326)
/gene="speE"
/locus_tag="ECOK1_0123"
/note="S-adenosylmethionine-dependent methyltransferases
(SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
that use S-adenosyl-L-methionine (SAM or AdoMet) as a
substrate for methyltransfer, creating the product
S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
cd02440"
/db_xref="CDD:100107"
misc_feature complement(order(142093..142095,142144..142152,
142240..142245,142297..142317))
/gene="speE"
/locus_tag="ECOK1_0123"
/note="S-adenosylmethionine binding site [chemical
binding]; other site"
/db_xref="CDD:100107"
gene complement(142672..143019)
/locus_tag="ECOK1_0124"
/db_xref="GeneID:12688692"
CDS complement(142672..143019)
/locus_tag="ECOK1_0124"
/note="identified by similarity to GB:AAV76203.1"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099379.1"
/db_xref="GI:386597873"
/db_xref="GeneID:12688692"
/translation="MKTFFRTVLFGSLMAVCANSYALSESEAEDMADLTAVFVFLKND
CGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKA
LARDSLSLLAYVK"
misc_feature complement(142705..>142935)
/locus_tag="ECOK1_0124"
/note="Bacterial chaperone lipoprotein (PulS_OutS);
Region: PulS_OutS; cl09898"
/db_xref="CDD:245186"
gene 143146..144735
/gene="cueO"
/locus_tag="ECOK1_0125"
/db_xref="GeneID:12688693"
CDS 143146..144735
/gene="cueO"
/locus_tag="ECOK1_0125"
/note="identified by similarity to SP:P36649; match to
protein family HMM PF07731; match to protein family HMM
PF07732; match to protein family HMM TIGR01409"
/codon_start=1
/transl_table=11
/product="copper oxidase CueO"
/protein_id="YP_006099380.1"
/db_xref="GI:386597874"
/db_xref="GeneID:12688693"
/translation="MILFRLLKNKEITMQRRDFLKYSVALGVASALPLWSRAVFAAER
PTLPIPDLLTTDARNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKLQRGKAVTVD
IYNQLTEETTLHWHGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGK
TGRQVAMGLAGLVVIEDDEILKLMLPKQWGIDDVPVIVQDKKFNADGQIDYQLDVMTA
AVGWFGDTLLTNGAIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGL
LPEPVKVSELPVLMGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQP
IAISASGALPDTLSSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGM
DHSQMMGHMGHGNMNHMNHSGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGV
GDMMLHPFHIHGTQFRILSENGKPPATHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHA
YMAHCHLLEHEDTGMMLGFTV"
misc_feature 143185..144732
/gene="cueO"
/locus_tag="ECOK1_0125"
/note="multicopper oxidase; Provisional; Region: PRK10965"
/db_xref="CDD:182870"
misc_feature 143335..143682
/gene="cueO"
/locus_tag="ECOK1_0125"
/note="Multicopper oxidase; Region: Cu-oxidase_3;
pfam07732"
/db_xref="CDD:203745"
misc_feature <143878..>144054
/gene="cueO"
/locus_tag="ECOK1_0125"
/note="Cytochrome C oxidase subunit II, periplasmic
domain; Region: COX2; cl11412"
/db_xref="CDD:209309"
misc_feature 144388..144732
/gene="cueO"
/locus_tag="ECOK1_0125"
/note="Multicopper oxidase; Region: Cu-oxidase_2;
pfam07731"
/db_xref="CDD:203744"
gene complement(144782..147172)
/gene="gcd"
/locus_tag="ECOK1_0126"
/db_xref="GeneID:12688694"
CDS complement(144782..147172)
/gene="gcd"
/locus_tag="ECOK1_0126"
/EC_number="1.1.5.2"
/note="identified by similarity to SP:P15877; match to
protein family HMM PF01011; match to protein family HMM
TIGR03074"
/codon_start=1
/transl_table=11
/product="quinoprotein glucose dehydrogenase"
/protein_id="YP_006099381.1"
/db_xref="GI:386597875"
/db_xref="GeneID:12688694"
/translation="MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYP
IAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGI
WLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEISGTLSADTTPAEAI
SPVADQDWPAYGRNQEGQRFSPLKQINTDNVHKLKEAWVFRTGDVKQPNDPGEITNEV
TPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAE
TASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYE
PTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSD
EHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
GKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELV
VPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRVMFHQM
RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGN
PMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEV
VWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK"
misc_feature complement(144797..147076)
/gene="gcd"
/locus_tag="ECOK1_0126"
/note="membrane-bound PQQ-dependent dehydrogenase,
glucose/quinate/shikimate family; Region: PQQ_membr_DH;
TIGR03074"
/db_xref="CDD:200239"
misc_feature complement(144800..146671)
/gene="gcd"
/locus_tag="ECOK1_0126"
/note="Membrane-bound PQQ-dependent glucose dehydrogenase;
Region: PQQ_mGDH; cd10280"
/db_xref="CDD:199838"
misc_feature complement(order(144803..144805,144809..144811,
144938..144940,144947..144955,144962..144964,
144968..144970,145121..145123,145130..145138,
145145..145147,145151..145153,145646..145648,
145655..145663,145670..145672,145676..145678,
145808..145810,145817..145825,145832..145834,
145838..145840,146042..146044,146051..146059,
146066..146068,146072..146074,146240..146242,
146249..146257,146264..146266,146270..146272,
146429..146431,146438..146446,146453..146455,
146459..146461,146579..146581,146588..146596))
/gene="gcd"
/locus_tag="ECOK1_0126"
/note="Trp docking motif [polypeptide binding]; other
site"
/db_xref="CDD:199838"
misc_feature complement(order(145037..145039,145694..145696,
145961..145963,146117..146122,146165..146167,
146375..146377,146390..146395,146522..146524))
/gene="gcd"
/locus_tag="ECOK1_0126"
/note="putative active site [active]"
/db_xref="CDD:199838"
gene 147378..147914
/gene="hpt"
/locus_tag="ECOK1_0127"
/db_xref="GeneID:12688695"
CDS 147378..147914
/gene="hpt"
/locus_tag="ECOK1_0127"
/EC_number="2.4.2.8"
/note="identified by similarity to SP:P0A9M2; match to
protein family HMM PF00156; match to protein family HMM
TIGR01203"
/codon_start=1
/transl_table=11
/product="hypoxanthine phosphoribosyltransferase"
/protein_id="YP_006099382.1"
/db_xref="GI:386597876"
/db_xref="GeneID:12688695"
/translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRG
SFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
DSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
AQRYRHLPYIGKVILLDE"
misc_feature 147429..147785
/gene="hpt"
/locus_tag="ECOK1_0127"
/note="Phosphoribosyl transferase (PRT)-type I domain;
Region: PRTases_typeI; cd06223"
/db_xref="CDD:206754"
misc_feature order(147501..147503,147507..147509,147672..147680,
147684..147698,147768..147770)
/gene="hpt"
/locus_tag="ECOK1_0127"
/note="active site"
/db_xref="CDD:206754"
gene complement(147955..148617)
/gene="can"
/locus_tag="ECOK1_0128"
/db_xref="GeneID:12688696"
CDS complement(147955..148617)
/gene="can"
/locus_tag="ECOK1_0128"
/note="identified by match to protein family HMM PF00484"
/codon_start=1
/transl_table=11
/product="carbonic anhydrase"
/protein_id="YP_006099383.1"
/db_xref="GI:386597877"
/db_xref="GeneID:12688696"
/translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCG
GVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH
STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHIN
HK"
misc_feature complement(148045..148587)
/gene="can"
/locus_tag="ECOK1_0128"
/note="Carbonic anhydrases (CA) are zinc-containing
enzymes that catalyze the reversible hydration of carbon
dioxide in a two-step mechanism in which the nucleophilic
attack of a zinc-bound hydroxide ion on carbon dioxide is
followed by the regeneration of an...; Region:
beta_CA_cladeA; cd00883"
/db_xref="CDD:238448"
misc_feature complement(order(148075..148077,148315..148317,
148324..148326,148354..148356,148369..148371,
148435..148437,148444..148446,148480..148488,
148492..148494,148513..148515,148519..148521))
/gene="can"
/locus_tag="ECOK1_0128"
/note="active site clefts [active]"
/db_xref="CDD:238448"
misc_feature complement(order(148315..148317,148324..148326,
148486..148488,148492..148494))
/gene="can"
/locus_tag="ECOK1_0128"
/note="zinc binding site [ion binding]; other site"
/db_xref="CDD:238448"
misc_feature complement(order(148054..148056,148060..148062,
148066..148071,148075..148077,148261..148263,
148369..148374,148381..148386,148426..148428,
148432..148434,148438..148446,148459..148461,
148465..148470,148474..148476,148480..148491))
/gene="can"
/locus_tag="ECOK1_0128"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:238448"
gene 148726..149652
/locus_tag="ECOK1_0129"
/db_xref="GeneID:12688697"
CDS 148726..149652
/locus_tag="ECOK1_0129"
/note="identified by match to protein family HMM PF00005"
/codon_start=1
/transl_table=11
/product="ABC transporter ATP-binding protein"
/protein_id="YP_006099384.1"
/db_xref="GI:386597878"
/db_xref="GeneID:12688697"
/translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
STTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQ
AGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
SMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLS
EQGIQVLSMRNKANRLEELFVSLVNEKQGDRT"
misc_feature 148726..149631
/locus_tag="ECOK1_0129"
/note="ABC-type multidrug transport system, ATPase
component [Defense mechanisms]; Region: CcmA; COG1131"
/db_xref="CDD:224054"
misc_feature 148738..149367
/locus_tag="ECOK1_0129"
/note="ATP-binding cassette domain of the drug resistance
transporter and related proteins, subfamily A; Region:
ABC_DR_subfamily_A; cd03230"
/db_xref="CDD:213197"
misc_feature 148837..148860
/locus_tag="ECOK1_0129"
/note="Walker A/P-loop; other site"
/db_xref="CDD:213197"
misc_feature order(148846..148851,148855..148863,148978..148980,
149206..149211,149305..149307)
/locus_tag="ECOK1_0129"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:213197"
misc_feature 148969..148980
/locus_tag="ECOK1_0129"
/note="Q-loop/lid; other site"
/db_xref="CDD:213197"
misc_feature 149134..149163
/locus_tag="ECOK1_0129"
/note="ABC transporter signature motif; other site"
/db_xref="CDD:213197"
misc_feature 149194..149211
/locus_tag="ECOK1_0129"
/note="Walker B; other site"
/db_xref="CDD:213197"
misc_feature 149218..149229
/locus_tag="ECOK1_0129"
/note="D-loop; other site"
/db_xref="CDD:213197"
misc_feature 149293..149313
/locus_tag="ECOK1_0129"
/note="H-loop/switch region; other site"
/db_xref="CDD:213197"
gene 149649..150419
/locus_tag="ECOK1_0130"
/db_xref="GeneID:12688698"
CDS 149649..150419
/locus_tag="ECOK1_0130"
/note="identified by match to protein family HMM PF01061"
/codon_start=1
/transl_table=11
/product="ABC transporter permease"
/protein_id="YP_006099385.1"
/db_xref="GI:386597879"
/db_xref="GeneID:12688698"
/translation="MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
LIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPT
HVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
LGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS"
misc_feature 149649..150416
/locus_tag="ECOK1_0130"
/note="inner membrane transport permease; Provisional;
Region: PRK15066"
/db_xref="CDD:237896"
misc_feature 149649..150413
/locus_tag="ECOK1_0130"
/note="ABC-type multidrug transport system, permease
component [Defense mechanisms]; Region: COG0842"
/db_xref="CDD:223912"
gene 150524..150964
/locus_tag="ECOK1_0131"
/db_xref="GeneID:12688699"
CDS 150524..150964
/locus_tag="ECOK1_0131"
/note="identified by match to protein family HMM PF03610"
/codon_start=1
/transl_table=11
/product="PTS system transporter subunit IIA"
/protein_id="YP_006099386.1"
/db_xref="GI:386597880"
/db_xref="GeneID:12688699"
/translation="MLGWVITCHDDRAQEILDALEKKHGALLQCRAVNFWRGLSSNML
SRMMCDALHETDSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMMA
CRETMTSSAFREHIVELGAPEVSSLWHQQQKNPPFVLKHNLYEY"
misc_feature 150527..150883
/locus_tag="ECOK1_0131"
/note="PTS_IIA, PTS system, mannose/sorbose specific IIA
subunit. The bacterial phosphoenolpyruvate: sugar
phosphotransferase system (PTS) is a multi-protein system
involved in the regulation of a variety of metabolic and
transcriptional processes. This family...; Region:
PTS_IIA_man; cd00006"
/db_xref="CDD:28890"
misc_feature order(150548..150550,150590..150595,150626..150628,
150734..150736,150827..150829)
/locus_tag="ECOK1_0131"
/note="active pocket/dimerization site"
/db_xref="CDD:28890"
misc_feature order(150548..150550,150719..150721,150734..150736)
/locus_tag="ECOK1_0131"
/note="active site"
/db_xref="CDD:28890"
misc_feature 150548..150550
/locus_tag="ECOK1_0131"
/note="phosphorylation site [posttranslational
modification]"
/db_xref="CDD:28890"
gene 151028..152257
/locus_tag="ECOK1_0132"
/db_xref="GeneID:12688700"
CDS 151028..152257
/locus_tag="ECOK1_0132"
/note="identified by match to protein family HMM PF01522"
/codon_start=1
/transl_table=11
/product="polysaccharide deacetylase domain-containing
protein"
/protein_id="YP_006099387.1"
/db_xref="GI:386597881"
/db_xref="GeneID:12688700"
/translation="MYKQAVILLLMLFTASVSAALPARYMQTIENAAVWAQIGDKMVT
VGNIRAGQIIAVEPTAASYYVFNFGFGKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSN
QNLITRKDTPVYNAPSVGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
ALDAQPDNGLPVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMAQ
LEGYVKNKINLPARAVVITFDDGLKSVSRYAYPVLKQYGMKATAFIVTSRIKRHPQKW
NPKSLQFMSVSELNEIRDVFDFQSHTHFLHRIDGYRRPILLSRSEHNILFDFARSRRA
LAQFNPHVLYLSYPFGGFNDKAVKAAKEAGFHLAVTTMKGKVKPGDNPLLLKRLYILR
TDSLETMSRLVSNQPQG"
misc_feature 151715..152224
/locus_tag="ECOK1_0132"
/note="Putative catalytic polysaccharide deacetylase
domain of uncharacterized protein yadE and similar
proteins; Region: CE4_yadE_5s; cd10966"
/db_xref="CDD:213024"
misc_feature order(151742..151747,151928..151930,151943..151945,
152069..152077)
/locus_tag="ECOK1_0132"
/note="putative active site [active]"
/db_xref="CDD:213024"
misc_feature order(151745..151747,151928..151930,151943..151945)
/locus_tag="ECOK1_0132"
/note="putative metal binding site [ion binding]; other
site"
/db_xref="CDD:213024"
gene complement(152261..152641)
/gene="panD"
/locus_tag="ECOK1_0133"
/db_xref="GeneID:12688701"
CDS complement(152261..152641)
/gene="panD"
/locus_tag="ECOK1_0133"
/EC_number="4.1.1.11"
/note="identified by match to protein family HMM PF02261;
match to protein family HMM TIGR00223"
/codon_start=1
/transl_table=11
/product="aspartate 1-decarboxylase"
/protein_id="YP_006099388.1"
/db_xref="GI:386597882"
/db_xref="GeneID:12688701"
/translation="MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAI
DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWR
PNVAYFEGDNEMKRTAKAIPVQVA"
misc_feature complement(152306..152635)
/gene="panD"
/locus_tag="ECOK1_0133"
/note="Aspartate alpha-decarboxylase or L-aspartate
1-decarboxylase, a pyruvoyl group-dependent decarboxylase
in beta-alanine production; Region: Asp_decarbox; cd06919"
/db_xref="CDD:132994"
misc_feature complement(order(152339..152341,152366..152374,
152384..152386,152408..152413,152417..152422,
152468..152482,152486..152488,152495..152497,
152501..152503,152513..152518,152525..152527,
152531..152533,152573..152584,152606..152611,
152615..152617,152621..152635))
/gene="panD"
/locus_tag="ECOK1_0133"
/note="tetramerization interface [polypeptide binding];
other site"
/db_xref="CDD:132994"
misc_feature complement(order(152468..152470,152567..152572,
152609..152611,152615..152617))
/gene="panD"
/locus_tag="ECOK1_0133"
/note="active site"
/db_xref="CDD:132994"
gene 152915..153799
/locus_tag="ECOK1_0134"
/db_xref="GeneID:12688702"
CDS 152915..153799
/locus_tag="ECOK1_0134"
/note="identified by match to protein family HMM PF04754;
match to protein family HMM TIGR01784"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099389.1"
/db_xref="GI:386597883"
/db_xref="GeneID:12688702"
/translation="MDAPSTTPHDAVFKQFLMHAETARDFLDIHLPAELRELCDLDTL
HLESGSFIEESLKGHSTDVLYSVQMQGSTGYLHVVIEHQSKPDKKMAFRMMRYSIAAM
HRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDMFYSPELARRVYNSPFPLVDITI
TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSGSQLVAMQNYMLQR
GHTEQADLFYGVVRDRETGGESMMTLAQWFEEKGIQQGRQEVSQEFALRLLSKGMSRE
DVAEMANLPLAEIDKMIN"
misc_feature 152918..153781
/locus_tag="ECOK1_0134"
/note="hypothetical protein; Provisional; Region:
PRK09956"
/db_xref="CDD:182167"
misc_feature 152933..153538
/locus_tag="ECOK1_0134"
/note="Putative transposase, YhgA-like; Region:
Transposase_31; pfam04754"
/db_xref="CDD:203082"
gene complement(153881..154732)
/gene="panC"
/locus_tag="ECOK1_0135"
/db_xref="GeneID:12688703"
CDS complement(153881..154732)
/gene="panC"
/locus_tag="ECOK1_0135"
/EC_number="6.3.2.1"
/note="identified by match to protein family HMM PF02569;
match to protein family HMM TIGR00018; match to protein
family HMM TIGR00125"
/codon_start=1
/transl_table=11
/product="pantoate--beta-alanine ligase"
/protein_id="YP_006099390.1"
/db_xref="GI:386597884"
/db_xref="GeneID:12688703"
/translation="MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEA
KARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNG
TETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
KMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAG
ERDLDEIIAIAGQELNEKGFRSDDIQIRDADTLLEVSENSKRAVILVAAWLGDARLID
NKLVELA"
misc_feature complement(153902..154732)
/gene="panC"
/locus_tag="ECOK1_0135"
/note="Pantoate-beta-alanine ligase; Region: PanC;
cd00560"
/db_xref="CDD:185673"
misc_feature complement(order(154166..154177,154199..154207,
154268..154270,154277..154282,154286..154291,
154331..154336,154343..154345,154520..154522,
154550..154552,154559..154561,154613..154615,
154622..154627,154631..154633,154640..154651))
/gene="panC"
/locus_tag="ECOK1_0135"
/note="active site"
/db_xref="CDD:185673"
misc_feature complement(order(154175..154180,154199..154204,
154268..154270,154277..154282,154286..154291,
154331..154336,154550..154552,154613..154615,
154622..154624,154631..154633,154643..154651))
/gene="panC"
/locus_tag="ECOK1_0135"
/note="ATP-binding site [chemical binding]; other site"
/db_xref="CDD:185673"
misc_feature complement(order(154268..154270,154322..154324,
154331..154336,154550..154552,154559..154561,
154643..154645,154649..154651))
/gene="panC"
/locus_tag="ECOK1_0135"
/note="pantoate-binding site; other site"
/db_xref="CDD:185673"
misc_feature complement(154622..154633)
/gene="panC"
/locus_tag="ECOK1_0135"
/note="HXXH motif; other site"
/db_xref="CDD:185673"
gene complement(154744..155538)
/gene="panB"
/locus_tag="ECOK1_0136"
/db_xref="GeneID:12688704"
CDS complement(154744..155538)
/gene="panB"
/locus_tag="ECOK1_0136"
/EC_number="2.1.2.11"
/note="identified by match to protein family HMM PF02548;
match to protein family HMM TIGR00222"
/codon_start=1
/transl_table=11
/product="3-methyl-2-oxobutanoate
hydroxymethyltransferase"
/protein_id="YP_006099391.1"
/db_xref="GI:386597885"
/db_xref="GeneID:12688704"
/translation="MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFAEEGLNVMLVG
DSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAAT
VMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAG
DRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDA
FGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH"
misc_feature complement(154768..155523)
/gene="panB"
/locus_tag="ECOK1_0136"
/note="Ketopantoate hydroxymethyltransferase (KPHMT) is
the first enzyme in the pantothenate biosynthesis pathway.
Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes
the first committed step in the biosynthesis of
pantothenate (vitamin B5), which is a...; Region:
KPHMT-like; cd06557"
/db_xref="CDD:119342"
misc_feature complement(order(154816..154830,154837..154839,
154879..154884,154891..154893,155011..155013,
155095..155106,155110..155115,155143..155160,
155212..155214,155224..155229,155236..155238,
155248..155250,155275..155280,155317..155319,
155326..155328,155335..155340,155347..155349,
155362..155367,155377..155394,155398..155400,
155443..155445,155452..155463,155518..155523))
/gene="panB"
/locus_tag="ECOK1_0136"
/note="oligomerization interface [polypeptide binding];
other site"
/db_xref="CDD:119342"
misc_feature complement(order(154897..154899,154903..154905,
154996..154998,155116..155118,155131..155133,
155203..155205,155287..155289,155401..155409,
155413..155415,155470..155472))
/gene="panB"
/locus_tag="ECOK1_0136"
/note="active site"
/db_xref="CDD:119342"
misc_feature complement(order(155203..155205,155287..155289,
155404..155406))
/gene="panB"
/locus_tag="ECOK1_0136"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:119342"
gene complement(155650..156915)
/locus_tag="ECOK1_0137"
/db_xref="GeneID:12688705"
CDS complement(155650..156915)
/locus_tag="ECOK1_0137"
/note="identified by match to protein family HMM PF00419"
/codon_start=1
/transl_table=11
/product="putative fimbrial protein"
/protein_id="YP_006099392.1"
/db_xref="GI:386597886"
/db_xref="GeneID:12688705"
/translation="MKIFFRYFLFLALCSCCYIASAGTDDHVGYVVGNNYGVGPSGQK
WRETGPNGDVTVKFRYGSVTNNLVFYKPTQLGPTGVSLKWAQLDSASGGGFLYCNRSG
STSGGPMHIENKMVDSGKSYGGHKLFKTSVPGLYYTLAISNIWSTYTYTDINPSGMYI
GDSTSQSFNWRGESEQTLYWSCNNANTKNKYWAVGGVMQTLTIEFYTDTDFNPTTNQR
VTLSRTDNYLYSFKAYGAGIGINDYSYFLKIDFDLTDIVLTNPTCFTAALSGSSVSGS
TVKMGDYTPAQIKNGATAVPFDITLQNCIRVRNIETKLKSNKVGSVSKELLANTLTGN
DAAKGVGVLIEGLKNTKSAQMVLKPNDATSIYKDYETEDDTTGGIYPDKGNGTSQPLH
FQATLKQDGNIAIEPGDFKATSTFQVTYP"
misc_feature complement(155653..156915)
/locus_tag="ECOK1_0137"
/note="putative fimbrial-like adhesin protein;
Provisional; Region: PRK09723"
/db_xref="CDD:170067"
gene complement(156965..157561)
/locus_tag="ECOK1_0138"
/db_xref="GeneID:12688706"
CDS complement(156965..157561)
/locus_tag="ECOK1_0138"
/note="identified by similarity to GB:CAD01338.1"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099393.1"
/db_xref="GI:386597887"
/db_xref="GeneID:12688706"
/translation="MRPTQRNLMKKSILLLSLLFSATSPVVAGQDVDIVANIKNNTCQ
SGISNNGNIDLGVVGVGDFTGNISAENYHPGGKEFTITVQDCTLQGTGNVLNQLHINF
RALSGVMATGSSQIFANEDNAGAKNVGVVIFSIQDPANTFNVLSATGSSRSVYPVMSS
ALNNSSWKFSTRMQKIDPALNVTSGPLISHVLVDIYYE"
misc_feature complement(156968..157495)
/locus_tag="ECOK1_0138"
/note="putative fimbrial protein StaF; Provisional;
Region: PRK15262"
/db_xref="CDD:185170"
gene complement(157588..158196)
/locus_tag="ECOK1_0139"
/db_xref="GeneID:12688707"
CDS complement(157588..158196)
/locus_tag="ECOK1_0139"
/note="identified by match to protein family HMM PF00419"
/codon_start=1
/transl_table=11
/product="putative fimbrial protein"
/protein_id="YP_006099394.1"
/db_xref="GI:386597888"
/db_xref="GeneID:12688707"
/translation="MMILKKLCYGLSGSLFLASSLLTISSHAATDSIGLTVTTDVEMG
TCTSTLTDDGTTKISTINFGDVYISEINAETKIKTFKLQFKDCAGIPGKKAKIKLTTR
ALCEGNSNNGPGFANASTATAKAAAVAVEVWSTSTPGKNGAKQFSCVTPATEEVSIAN
ATGSNVVDYPMSAVLVVAKDKTVTNVTAGDFTAPATFTVTYN"
misc_feature complement(157591..158130)
/locus_tag="ECOK1_0139"
/note="putative fimbrial protein StaE; Provisional;
Region: PRK15263"
/db_xref="CDD:185171"
gene complement(158208..158774)
/locus_tag="ECOK1_0140"
/db_xref="GeneID:12688708"
CDS complement(158208..158774)
/locus_tag="ECOK1_0140"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099395.1"
/db_xref="GI:386597889"
/db_xref="GeneID:12688708"
/translation="MIKITPHKITILMGLLLSPSVFATDVNVDFTATVKATTCNITLT
GTNVTDNGKDKYTLVIPSMGMDKIANKTAQSEANFKLVANGCSSGISWIDTTLTGNQS
GSSPALIIPLASDTTSTTSYIGMGFKRKATSGDTFLKPNSAEYIRWSASEISTDGLEM
TVALRETSVGKGVPGKFRALATFNFSYQ"
misc_feature complement(158211..158708)
/locus_tag="ECOK1_0140"
/note="Fimbrial protein; Region: Fimbrial; cl01416"
/db_xref="CDD:207406"
gene complement(158791..161379)
/locus_tag="ECOK1_0141"
/db_xref="GeneID:12688709"
CDS complement(158791..161379)
/locus_tag="ECOK1_0141"
/note="identified by match to protein family HMM PF00577"
/codon_start=1
/transl_table=11
/product="outer membrane usher protein"
/protein_id="YP_006099396.1"
/db_xref="GI:386597890"
/db_xref="GeneID:12688709"
/translation="MTIKSTNHLTHIATFCALLYSNSALCAELVEYDHTFLMGKDASN
IDLSRYTEGNPTLPGIYDVSVYVNDQPIMSQSIAFAVIEGKKNAQACITQKNLLQFHI
SSPDKNSEKAILLKRDDDLGDCLNLAEMIPQSSIRYDVNDQRLDIDVPQAWIMKNYQN
YVDPSLWENGINAAMLSYNLNGYHSESPGRTNDSIYAAFNGGINLGAWRLRASGNYNW
MTNVHSDYDFQNRYLQRDLASLRSQLVIGESYTTGETFDSVRIRGIRLYSDSRMLPPV
LASFAPIIHGVANTNAKVTVMQNGYKIYETTVPPGAFAIDDLSPSGYGSDLIVTIEEA
DGTKRTFSQPFSSVVQMLRPGVGRWDISAGQVLKDSIQDEPNLFQASYYYGLNNYLTG
YTGIQLTDNNYTAGLLGLGMNTPVGAFSVDVTHSNVSIPDDKTYQGQSYRISWNKLFE
NTSTSLNIAAYRYSTQHYLGLNDALTLIDEVEHPEQDLEPKSMRNYSRMKNQVTVSIN
QPLKFEKKDYGSFYLSGSWSDYWASGQNSTNYSIGYSNSASWGSYSISAQRSLNEDGQ
TDDSIYLSFTIPIENLLGTEHRSSGFQSIDTQLNSDFKGNNQLNISSSGYSDTNRISY
SVNTGYMMNKSSDDLSYIGGYASYESPWGTLSGSASASSDNSRQFSLNTDGGFVLHSG
GLTFSNDSFSDSDTLAVIQAPGAKGARINYGNSTVDRWGYGVTSALSPYHENRIALDI
NDLENDVELKSTSTVAVPRQGAVVFADFETVQGQSAIMNIVRSDGKNIPFAADIYDEQ
NNIIGNVGQGGQAFVRGIGQEGNIRITWIEEGKPVSCFAHYQQNTTSEKIAQSIILNG
LRCQIQ"
misc_feature complement(158794..161379)
/locus_tag="ECOK1_0141"
/note="putative fimbrial outer membrane usher protein;
Provisional; Region: PRK09828"
/db_xref="CDD:182098"
misc_feature complement(160831..161289)
/locus_tag="ECOK1_0141"
/note="PapC N-terminal domain; Region: PapC_N; pfam13954"
/db_xref="CDD:206124"
misc_feature complement(159076..160794)
/locus_tag="ECOK1_0141"
/note="Type VII secretion system (T7SS), usher protein;
Region: Usher; pfam00577"
/db_xref="CDD:201318"
misc_feature complement(158842..159048)
/locus_tag="ECOK1_0141"
/note="PapC C-terminal domain; Region: PapC_C; pfam13953"
/db_xref="CDD:206123"
gene complement(161414..162154)
/locus_tag="ECOK1_0142"
/db_xref="GeneID:12688710"
CDS complement(161414..162154)
/locus_tag="ECOK1_0142"
/note="identified by match to protein family HMM PF00345;
match to protein family HMM PF02753"
/codon_start=1
/transl_table=11
/product="pili assembly chaperone"
/protein_id="YP_006099397.1"
/db_xref="GI:386597891"
/db_xref="GeneID:12688710"
/translation="MFFNTKHTAALCLASCMAFSSSAIADIVISGTRVVYKSEQKSVN
VRLENKGNNPLLVQSWLDTGDDNAEPGSITVPFTATPPVSRIDAKRGQTIKLMYTASS
ALPKDRESVFWFNVLEVPPKPDAAKAANQSLLQLAFRTRIKLFYRPEGLSGISSDAPL
ALKWSWATSEGKAALRVDNPTPYYVSFSSGDLEANGKRYPLDMTMIAPFSNDVIKVNG
MSGRTSSAKVHFFAINDFGGSIEGNANL"
misc_feature complement(161417..162154)
/locus_tag="ECOK1_0142"
/note="putative chaperone protein EcpD; Provisional;
Region: PRK09926"
/db_xref="CDD:236634"
misc_feature complement(161699..162076)
/locus_tag="ECOK1_0142"
/note="Gram-negative pili assembly chaperone, N-terminal
domain; Region: Pili_assembly_N; pfam00345"
/db_xref="CDD:215870"
misc_feature complement(161429..161632)
/locus_tag="ECOK1_0142"
/note="Gram-negative pili assembly chaperone, C-terminal
domain; Region: Pili_assembly_C; pfam02753"
/db_xref="CDD:217216"
gene complement(162263..162853)
/locus_tag="ECOK1_0143"
/db_xref="GeneID:12688711"
CDS complement(162263..162853)
/locus_tag="ECOK1_0143"
/note="identified by similarity to SP:P08190; match to
protein family HMM PF00419"
/codon_start=1
/transl_table=11
/product="fimbrial protein"
/protein_id="YP_006099398.1"
/db_xref="GI:386597892"
/db_xref="GeneID:12688711"
/translation="MSKKLGFALSGIMLAMAAGTAFAANDMDGGQLNISGLVVDNTCE
ARVDGGNKDGLILLQTATVAEITDGVLDTTVGAKAKPFSITIDCSKANPAPGTTAKMT
FGSVFFGNSKGTLNNDMSINTPSDGVNIALHNIEGSTIKQVQVNNPGDVYSKTLDSTS
KSATYDFKASYVRADASKAATAGYVKTNSAYTITYQ"
misc_feature complement(162266..162775)
/locus_tag="ECOK1_0143"
/note="Fimbrial protein; Region: Fimbrial; cl01416"
/db_xref="CDD:242492"
gene complement(163215..163694)
/gene="folK"
/locus_tag="ECOK1_0144"
/db_xref="GeneID:12688712"
CDS complement(163215..163694)
/gene="folK"
/locus_tag="ECOK1_0144"
/EC_number="2.7.6.3"
/note="identified by similarity to SP:P26281; match to
protein family HMM PF01288; match to protein family HMM
TIGR01498"
/codon_start=1
/transl_table=11
/product="2-amino-4-hydroxy-6-
hydroxymethyldihydropteridine pyrophosphokinase"
/protein_id="YP_006099399.1"
/db_xref="GI:386597893"
/db_xref="GeneID:12688712"
/translation="MTVAYIAIGSNLASPLEQVNAALKALGDIPESRILAVSSFYRTP
PLGPQDQPDYLNAAVALKTTLAPEGLLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
GNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGLSLVEALQAKGFNELDKW"
misc_feature complement(163299..163685)
/gene="folK"
/locus_tag="ECOK1_0144"
/note="7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
(HPPK). Folate derivatives are essential cofactors in the
biosynthesis of purines, pyrimidines, and amino acids as
well as formyl-tRNA. Mammalian cells are able to utilize
pre-formed folates after...; Region: HPPK; cd00483"
/db_xref="CDD:29601"
misc_feature complement(order(163323..163325,163329..163331,
163344..163349,163356..163358,163398..163403,
163407..163409,163416..163418,163425..163427,
163440..163442,163446..163448,163461..163463,
163470..163472,163482..163484,163527..163529,
163533..163535,163557..163559,163563..163568,
163668..163670))
/gene="folK"
/locus_tag="ECOK1_0144"
/note="catalytic center binding site [active]"
/db_xref="CDD:29601"
misc_feature complement(order(163329..163331,163344..163349,
163356..163358,163398..163403,163416..163418,
163440..163442,163446..163448,163461..163463,
163470..163472,163482..163484))
/gene="folK"
/locus_tag="ECOK1_0144"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:29601"
gene complement(163691..165055)
/gene="pcnB"
/locus_tag="ECOK1_0145"
/db_xref="GeneID:12688713"
CDS complement(163691..165055)
/gene="pcnB"
/locus_tag="ECOK1_0145"
/EC_number="2.7.7.19"
/note="identified by match to protein family HMM PF01743;
match to protein family HMM TIGR01942"
/codon_start=1
/transl_table=11
/product="poly(A) polymerase"
/protein_id="YP_006099400.1"
/db_xref="GI:386597894"
/db_xref="GeneID:12688713"
/translation="MLSREESEAEQAVARPQVTVIPREQHAISRKDISENALKVMYRL
NKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKLFRNCRLVGRRFRLAHVMF
GPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYS
VADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLRAVRFAAKLGMRISPETAE
PIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFPTITRYFTENG
DSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLETAQKIAQESGLTYHDAF
ALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLLEHPKFRAAYDL
LALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDEEPSPRRRTRRPRKRAPRR
EGTA"
misc_feature complement(163757..165055)
/gene="pcnB"
/locus_tag="ECOK1_0145"
/note="poly(A) polymerase I; Provisional; Region: pcnB;
PRK11623"
/db_xref="CDD:236939"
misc_feature complement(164522..164956)
/gene="pcnB"
/locus_tag="ECOK1_0145"
/note="Nucleotidyltransferase (NT) domain of ClassII
CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398"
/db_xref="CDD:143388"
misc_feature complement(order(164591..164593,164600..164611,
164717..164719,164732..164734,164771..164773,
164843..164845,164849..164851,164876..164881,
164888..164893))
/gene="pcnB"
/locus_tag="ECOK1_0145"
/note="active site"
/db_xref="CDD:143388"
misc_feature complement(order(164591..164593,164603..164611,
164843..164845,164849..164851,164879..164881,
164888..164893))
/gene="pcnB"
/locus_tag="ECOK1_0145"
/note="NTP binding site [chemical binding]; other site"
/db_xref="CDD:143388"
misc_feature complement(order(164732..164734,164843..164845,
164849..164851))
/gene="pcnB"
/locus_tag="ECOK1_0145"
/note="metal binding triad [ion binding]; metal-binding
site"
/db_xref="CDD:143388"
misc_feature complement(164240..164431)
/gene="pcnB"
/locus_tag="ECOK1_0145"
/note="Probable RNA and SrmB- binding site of polymerase
A; Region: PolyA_pol_RNAbd; pfam12627"
/db_xref="CDD:221674"
misc_feature complement(163757..164086)
/gene="pcnB"
/locus_tag="ECOK1_0145"
/note="Polymerase A arginine-rich C-terminus; Region:
PolyA_pol_arg_C; pfam12626"
/db_xref="CDD:221673"
gene complement(165148..166074)
/gene="gluQ"
/locus_tag="ECOK1_0146"
/db_xref="GeneID:12688714"
CDS complement(165148..166074)
/gene="gluQ"
/locus_tag="ECOK1_0146"
/EC_number="6.1.1.-"
/note="identified by match to protein family HMM PF00749;
match to protein family HMM TIGR03838"
/codon_start=1
/transl_table=11
/product="glutamyl-queuosine tRNA(Asp) synthetase"
/protein_id="YP_006099401.1"
/db_xref="GI:386597895"
/db_xref="GeneID:12688714"
/translation="MLPPYFLFKEMTDTHYIGRFAPSPSGELHFGSLIAALGSYLQAR
ARQGRWLVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHHAYREALAWL
HEQGLSYYCTCTRARIQSIGGIYDGHCRDLHHGPDNAAVRIRQQHPVTQFTDLLRGII
HADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVSEIVRGADLIEPTVRQISLYQLF
GWKVPDYIHLPLALNPQGAKLSKQNHAPALPKGDPRPVLIAALHFLGQQVETHWQDFS
VEQILQSAVKNWTLTAVPESAIVNSTFSNASC"
misc_feature complement(165166..166044)
/gene="gluQ"
/locus_tag="ECOK1_0146"
/note="glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region:
PRK05710"
/db_xref="CDD:180216"
misc_feature complement(165184..166020)
/gene="gluQ"
/locus_tag="ECOK1_0146"
/note="tRNA synthetases class I (E and Q), catalytic
domain; Region: tRNA-synt_1c; pfam00749"
/db_xref="CDD:189699"
misc_feature complement(order(165352..165357,165979..165990))
/gene="gluQ"
/locus_tag="ECOK1_0146"
/note="active site"
/db_xref="CDD:173912"
misc_feature complement(order(165352..165354,165979..165981,
165988..165990))
/gene="gluQ"
/locus_tag="ECOK1_0146"
/note="nucleotide binding site [chemical binding]; other
site"
/db_xref="CDD:173912"
misc_feature complement(165979..165990)
/gene="gluQ"
/locus_tag="ECOK1_0146"
/note="HIGH motif; other site"
/db_xref="CDD:173912"
misc_feature complement(165352..165357)
/gene="gluQ"
/locus_tag="ECOK1_0146"
/note="KMSKS motif; other site"
/db_xref="CDD:173912"
gene complement(166111..166566)
/gene="dksA"
/locus_tag="ECOK1_0147"
/db_xref="GeneID:12688715"
CDS complement(166111..166566)
/gene="dksA"
/locus_tag="ECOK1_0147"
/note="identified by match to protein family HMM PF01258;
match to protein family HMM TIGR02420"
/codon_start=1
/transl_table=11
/product="RNA polymerase-binding protein DksA"
/protein_id="YP_006099402.1"
/db_xref="GI:386597896"
/db_xref="GeneID:12688715"
/translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRIL
EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
misc_feature complement(166114..166566)
/gene="dksA"
/locus_tag="ECOK1_0147"
/note="RNA polymerase-binding transcription factor;
Provisional; Region: dksA; PRK10778"
/db_xref="CDD:182722"
gene complement(166744..167448)
/gene="sfsA"
/locus_tag="ECOK1_0148"
/db_xref="GeneID:12688716"
CDS complement(166744..167448)
/gene="sfsA"
/locus_tag="ECOK1_0148"
/note="identified by match to protein family HMM PF03749;
match to protein family HMM TIGR00230"
/codon_start=1
/transl_table=11
/product="sugar fermentation stimulation protein"
/protein_id="YP_006099403.1"
/db_xref="GI:386597897"
/db_xref="GeneID:12688716"
/translation="MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGC
ATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAIICVNTLWANRLTKEAILNESISELA
GYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAE
LSAEGMALKKSLPVTL"
misc_feature complement(166747..167448)
/gene="sfsA"
/locus_tag="ECOK1_0148"
/note="putative DNA-binding transcriptional regulator;
Reviewed; Region: PRK00347"
/db_xref="CDD:178983"
gene complement(167463..167993)
/gene="ligT"
/locus_tag="ECOK1_0149"
/db_xref="GeneID:12688717"
CDS complement(167463..167993)
/gene="ligT"
/locus_tag="ECOK1_0149"
/EC_number="6.5.1.-"
/note="identified by match to protein family HMM PF02834;
match to protein family HMM TIGR02258"
/codon_start=1
/transl_table=11
/product="2'-5' RNA ligase"
/protein_id="YP_006099404.1"
/db_xref="GI:386597898"
/db_xref="GeneID:12688717"
/translation="MSEPQRLFFAIDLPAEIREQIIRWRATHFPPEAGRPVAADNLHL
TLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYTVTEFTLYASSFA
RGRTRYTPLKRWALTQ"
misc_feature complement(167466..167993)
/gene="ligT"
/locus_tag="ECOK1_0149"
/note="2'-5' RNA ligase; Provisional; Region: PRK15124"
/db_xref="CDD:185079"
misc_feature complement(167727..167963)
/gene="ligT"
/locus_tag="ECOK1_0149"
/note="LigT like Phosphoesterase; Region: LigT_PEase;
pfam02834"
/db_xref="CDD:202422"
misc_feature complement(167496..167720)
/gene="ligT"
/locus_tag="ECOK1_0149"
/note="LigT like Phosphoesterase; Region: LigT_PEase;
pfam02834"
/db_xref="CDD:202422"
gene 168022..170496
/gene="hrpB"
/locus_tag="ECOK1_0150"
/db_xref="GeneID:12688718"
CDS 168022..170496
/gene="hrpB"
/locus_tag="ECOK1_0150"
/note="identified by match to protein family HMM PF00270;
match to protein family HMM PF00271; match to protein
family HMM PF04408; match to protein family HMM PF08482;
match to protein family HMM TIGR01970"
/codon_start=1
/transl_table=11
/product="ATP-dependent helicase HrpB"
/protein_id="YP_006099405.1"
/db_xref="GI:386597899"
/db_xref="GeneID:12688718"
/translation="MLQCGAKNVNPLERFVSSLPVAAVLPELLAALDGASQVLLSAPT
GAGKSTWLPLQLLAHPGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQ
NCVGPNTRLEVVTEGVLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQG
LRDDLKLLIMSATLDNDRLQQMLPEAPVVISEGRSFPVERRYLPLPAHQRFDEAVAVA
TAEMLRQESGSLLLFLPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPA
PQGMRKVVLATNIAETSLTIEGIRLVVDCAQERVARFDPRTGLTRLVTQRVSQASMTQ
RAGRAGRLEPGICLHLIAKEQAERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQMSW
LDQPPTVNLLAAKRLLRMLGALDGERLSAQGQKMATLGNDPRLAAMLVSAKNDDEAAT
AAKIAAILEEPPRMGNSDLGVAFSRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPLLA
RAYADRIARRRGQDERYQLANGMGAMLDADDALSRHEWLIAPLLLQGSASPDARILLA
LPVDIDELVQRCPQLVQQSDTVEWDDAQGTLKAWRRLQIGQLMVKVQPLAKPSEDELH
QAMLNGIRDKGLSVLNWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLATLETWLLP
HMTGVHSLRGLKSLDIYQALRGLLDWVMQQRLDSELPAHYTVPTGSRIAIRYHEDNPP
ALAVRMQEMFGEATNPTIAQGRVPLVLELLSPAQRPLQITRDLSAFWKGAYREVQKEM
KGRYPKHVWPDDPANTAPTRRTKKYS"
misc_feature 168124..170493
/gene="hrpB"
/locus_tag="ECOK1_0150"
/note="ATP-dependent RNA helicase HrpB; Provisional;
Region: PRK11664"
/db_xref="CDD:183267"
misc_feature 168133..168543
/gene="hrpB"
/locus_tag="ECOK1_0150"
/note="DEAD-like helicases superfamily. A diverse family
of proteins involved in ATP-dependent RNA or DNA
unwinding. This domain contains the ATP-binding region;
Region: DEXDc; cd00046"
/db_xref="CDD:28927"
misc_feature 168154..168168
/gene="hrpB"
/locus_tag="ECOK1_0150"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:28927"
misc_feature 168433..168444
/gene="hrpB"
/locus_tag="ECOK1_0150"
/note="putative Mg++ binding site [ion binding]; other
site"
/db_xref="CDD:28927"
misc_feature 168610..169071
/gene="hrpB"
/locus_tag="ECOK1_0150"
/note="Helicase superfamily c-terminal domain; associated
with DEXDc-, DEAD-, and DEAH-box proteins, yeast
initiation factor 4A, Ski2p, and Hepatitis C virus NS3
helicases; this domain is found in a wide variety of
helicases and helicase related proteins; may...; Region:
HELICc; cd00079"
/db_xref="CDD:28960"
misc_feature order(168724..168735,168802..168807,168880..168888)
/gene="hrpB"
/locus_tag="ECOK1_0150"
/note="nucleotide binding region [chemical binding]; other
site"
/db_xref="CDD:28960"
misc_feature order(168904..168906,169021..169023,169033..169035,
169042..169044)
/gene="hrpB"
/locus_tag="ECOK1_0150"
/note="ATP-binding site [chemical binding]; other site"
/db_xref="CDD:28960"
misc_feature 169249..>169350
/gene="hrpB"
/locus_tag="ECOK1_0150"
/note="Helicase associated domain (HA2) Add an annotation;
Region: HA2; smart00847"
/db_xref="CDD:197915"
misc_feature 170056..170454
/gene="hrpB"
/locus_tag="ECOK1_0150"
/note="ATP-dependent helicase C-terminal; Region: HrpB_C;
pfam08482"
/db_xref="CDD:149509"
gene 170590..173124
/gene="mrcB"
/locus_tag="ECOK1_0151"
/db_xref="GeneID:12688719"
CDS 170590..173124
/gene="mrcB"
/locus_tag="ECOK1_0151"
/EC_number="2.4.1.129"
/EC_number="3.4.-.-"
/note="identified by similarity to SP:P02919; match to
protein family HMM PF00905; match to protein family HMM
PF00912; match to protein family HMM TIGR02071"
/codon_start=1
/transl_table=11
/product="penicillin-binding protein 1B"
/protein_id="YP_006099406.1"
/db_xref="GI:386597900"
/db_xref="GeneID:12688719"
/translation="MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEE
PMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQL
PAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
FPDSKEGQVRACLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPR
SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNL
FLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYY
FGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYD
MLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAA
EKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSI
GSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLV
DALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLNPVPAMLLGALNLTPIEVAQA
FQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGT
GRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAM
SIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRVLPVWTSDPQSLCQQSE
MQQQPSGNPFDQSSQPQQQPQQQPAQQEQKDSDGVAGWIKDMFGSN"
misc_feature 170590..173118
/gene="mrcB"
/locus_tag="ECOK1_0151"
/note="bifunctional glycosyl transferase/transpeptidase;
Reviewed; Region: mrcB; PRK09506"
/db_xref="CDD:181917"
misc_feature 171196..171690
/gene="mrcB"
/locus_tag="ECOK1_0151"
/note="Transglycosylase; Region: Transgly; pfam00912"
/db_xref="CDD:201501"
misc_feature 172006..172731
/gene="mrcB"
/locus_tag="ECOK1_0151"
/note="Penicillin binding protein transpeptidase domain;
Region: Transpeptidase; cl01009"
/db_xref="CDD:207282"
gene complement(173189..173344)
/locus_tag="ECOK1_0152"
/db_xref="GeneID:12688720"
CDS complement(173189..173344)
/locus_tag="ECOK1_0152"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099407.1"
/db_xref="GI:386597901"
/db_xref="GeneID:12688720"
/translation="MVFLWCKVNDNVNENDYYKDEIIFETLAGSQAVRNLRIPEGSIN
NQMKRKG"
gene 173344..175587
/gene="fhuA"
/locus_tag="ECOK1_0153"
/db_xref="GeneID:12688721"
CDS 173344..175587
/gene="fhuA"
/locus_tag="ECOK1_0153"
/note="identified by similarity to SP:P06971; match to
protein family HMM PF00593; match to protein family HMM
PF07715; match to protein family HMM TIGR01783"
/codon_start=1
/transl_table=11
/product="ferrichrome-iron receptor"
/protein_id="YP_006099408.1"
/db_xref="GI:386597902"
/db_xref="GeneID:12688721"
/translation="MAPSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITV
TAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEA
LSYTPGVSVGTRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLE
RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDALD
DDGVYSYRLTGLARSANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGY
YGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLR
FAENKTSQNSVYGYGVCSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDT
QLQSKFATGDIDHTLLTGVDFMRMRNDINAWFGYDDSVPLLDLYNPVNTDFDFNAKDP
DNSGPYRILNKQKQTGVYVQDQAQWDKVLVTLGGRYDWADQESLNRVAGTTDKRDDKQ
FTWRGGVNYLFDNGVTPYFSYSESFEPSSQVGKDGNIFAPSKGKQYEVGVKYVPEDRP
IVVTGAVYNLTKTNNLMADPEGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYT
DAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANS
FKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQVV
ATATFRF"
misc_feature 173344..175584
/gene="fhuA"
/locus_tag="ECOK1_0153"
/note="ferrichrome outer membrane transporter;
Provisional; Region: PRK10044"
/db_xref="CDD:182206"
misc_feature 173587..175584
/gene="fhuA"
/locus_tag="ECOK1_0153"
/note="TonB dependent/Ligand-Gated channels are created by
a monomeric 22 strand (22,24) anti-parallel beta-barrel.
Ligands apparently bind to the large extracellular loops.
The N-terminal 150-200 residues form a plug from the
periplasmic end of barrel; Region: ligand_gated_channel;
cd01347"
/db_xref="CDD:73259"
misc_feature order(173587..173616,173644..173673,173710..173727,
173746..173748,173755..173775,173809..173841,
173875..173901)
/gene="fhuA"
/locus_tag="ECOK1_0153"
/note="N-terminal plug; other site"
/db_xref="CDD:73259"
misc_feature order(174361..174363,174490..174492)
/gene="fhuA"
/locus_tag="ECOK1_0153"
/note="ligand-binding site [chemical binding]; other site"
/db_xref="CDD:73259"
gene 175638..176435
/gene="fhuC"
/locus_tag="ECOK1_0154"
/db_xref="GeneID:12688722"
CDS 175638..176435
/gene="fhuC"
/locus_tag="ECOK1_0154"
/note="identified by similarity to SP:P07821; match to
protein family HMM PF00005"
/codon_start=1
/transl_table=11
/product="ferrichrome ABC transporter ATP-binding protein"
/protein_id="YP_006099409.1"
/db_xref="GI:386597903"
/db_xref="GeneID:12688722"
/translation="MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIG
HNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV
RELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYL
VALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY"
misc_feature 175638..176432
/gene="fhuC"
/locus_tag="ECOK1_0154"
/note="iron-hydroxamate transporter ATP-binding subunit;
Provisional; Region: PRK10575"
/db_xref="CDD:182561"
misc_feature 175674..176327
/gene="fhuC"
/locus_tag="ECOK1_0154"
/note="ATP-binding component of iron-siderophores, vitamin
B12 and hemin transporters and related proteins; Region:
ABC_Iron-Siderophores_B12_Hemin; cd03214"
/db_xref="CDD:213181"
misc_feature 175767..175790
/gene="fhuC"
/locus_tag="ECOK1_0154"
/note="Walker A/P-loop; other site"
/db_xref="CDD:213181"
misc_feature order(175776..175781,175785..175793,175911..175913,
176151..176156,176253..176255)
/gene="fhuC"
/locus_tag="ECOK1_0154"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:213181"
misc_feature 175902..175913
/gene="fhuC"
/locus_tag="ECOK1_0154"
/note="Q-loop/lid; other site"
/db_xref="CDD:213181"
misc_feature 176079..176108
/gene="fhuC"
/locus_tag="ECOK1_0154"
/note="ABC transporter signature motif; other site"
/db_xref="CDD:213181"
misc_feature 176139..176156
/gene="fhuC"
/locus_tag="ECOK1_0154"
/note="Walker B; other site"
/db_xref="CDD:213181"
misc_feature 176163..176174
/gene="fhuC"
/locus_tag="ECOK1_0154"
/note="D-loop; other site"
/db_xref="CDD:213181"
misc_feature 176241..176261
/gene="fhuC"
/locus_tag="ECOK1_0154"
/note="H-loop/switch region; other site"
/db_xref="CDD:213181"
gene 176435..177325
/gene="fhuD"
/locus_tag="ECOK1_0155"
/db_xref="GeneID:12688723"
CDS 176435..177325
/gene="fhuD"
/locus_tag="ECOK1_0155"
/note="identified by similarity to SP:P07822; match to
protein family HMM PF01497"
/codon_start=1
/transl_table=11
/product="ferrichrome ABC transporter, periplasmic
ferrichrome-binding protein"
/protein_id="YP_006099410.1"
/db_xref="GI:386597904"
/db_xref="GeneID:12688723"
/translation="MSGLPLISRRRLLTAMALSPLLWQMNTAHAAVIDPNRIVALEWL
PVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAHYED
FIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWG
STAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYG
ATLSAMHFVRILDNAIGGKA"
misc_feature 176534..177289
/gene="fhuD"
/locus_tag="ECOK1_0155"
/note="Fe3+-siderophore binding domain FhuD. These
proteins have been shown to function as initial receptors
in ABC transport of Fe3+-siderophores in many eubacterial
species. They belong to the TroA-like superfamily of
helical backbone metal receptor proteins...; Region: FhuD;
cd01146"
/db_xref="CDD:29749"
misc_feature 176591..177253
/gene="fhuD"
/locus_tag="ECOK1_0155"
/note="Periplasmic binding protein; Region: Peripla_BP_2;
pfam01497"
/db_xref="CDD:144914"
misc_feature order(176636..176638,176684..176689,176750..176752,
176999..177001)
/gene="fhuD"
/locus_tag="ECOK1_0155"
/note="siderophore binding site; other site"
/db_xref="CDD:29749"
gene 177322..179304
/gene="fhuB"
/locus_tag="ECOK1_0156"
/db_xref="GeneID:12688724"
CDS 177322..179304
/gene="fhuB"
/locus_tag="ECOK1_0156"
/note="identified by similarity to SP:P06972; match to
protein family HMM PF01032"
/codon_start=1
/transl_table=11
/product="ferrichrome ABC transporter permease FhuB"
/protein_id="YP_006099411.1"
/db_xref="GI:386597905"
/db_xref="GeneID:12688724"
/translation="MSKRIALFPVLLLALLVVAAAALTWMNFSQALPRSQWAQAAWSP
DIDVIEQMIFHYSLLPRLAISLLVGAGLGLVGVLFQQVLRNPLAEPTTLGVATGAQLG
ITVTTLWAIPGAMASQFAALAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLD
DGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPR
LMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDM
KVNDRVATERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWP
RIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWL
LPAGSLGAAVTLLIIMIAAGRGGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQV
LTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGMALTPTR
IALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFA
DWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR"
misc_feature 177322..179301
/gene="fhuB"
/locus_tag="ECOK1_0156"
/note="iron-hydroxamate transporter permease subunit;
Provisional; Region: PRK10577"
/db_xref="CDD:182563"
misc_feature 177571..178254
/gene="fhuB"
/locus_tag="ECOK1_0156"
/note="Transmembrane subunit (TM), of Periplasmic Binding
Protein (PBP)-dependent ATP-Binding Cassette (ABC)
transporters involved in the uptake of siderophores, heme,
vitamin B12, or the divalent cations Mg2+ and Zn2+.
PBP-dependent ABC transporters consist of...; Region:
TM_ABC_iron-siderophores_like; cd06550"
/db_xref="CDD:119348"
misc_feature order(177571..177579,177937..177942,177946..177954,
177958..177963,177967..177984,177988..177996,
178117..178119,178138..178140)
/gene="fhuB"
/locus_tag="ECOK1_0156"
/note="ABC-ATPase subunit interface; other site"
/db_xref="CDD:119348"
misc_feature order(177574..177576,177580..177582,177595..177597,
177754..177756,177760..177765,177772..177777,
177784..177789,177796..177798,177805..177810,
177814..177816,177847..177852,177859..177861,
178087..178089,178246..178248)
/gene="fhuB"
/locus_tag="ECOK1_0156"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:119348"
misc_feature order(177814..177816,177889..177891,178063..178065,
178075..178077,178207..178209,178237..178239)
/gene="fhuB"
/locus_tag="ECOK1_0156"
/note="putative PBP binding regions; other site"
/db_xref="CDD:119348"
misc_feature 178501..179286
/gene="fhuB"
/locus_tag="ECOK1_0156"
/note="Transmembrane subunit (TM), of Periplasmic Binding
Protein (PBP)-dependent ATP-Binding Cassette (ABC)
transporters involved in the uptake of siderophores, heme,
vitamin B12, or the divalent cations Mg2+ and Zn2+.
PBP-dependent ABC transporters consist of...; Region:
TM_ABC_iron-siderophores_like; cd06550"
/db_xref="CDD:119348"
misc_feature order(178555..178557,178567..178575,178936..178941,
178945..178953,178957..178962,178966..178983,
178987..178995,179116..179118,179137..179139)
/gene="fhuB"
/locus_tag="ECOK1_0156"
/note="ABC-ATPase subunit interface; other site"
/db_xref="CDD:119348"
misc_feature order(178570..178572,178576..178578,178591..178593,
178753..178755,178759..178764,178771..178776,
178783..178788,178795..178797,178804..178809,
178813..178815,178846..178851,178858..178860,
179086..179088,179242..179244,179251..179256,
179263..179265,179272..179277,179284..179286)
/gene="fhuB"
/locus_tag="ECOK1_0156"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:119348"
misc_feature order(178813..178815,178888..178890,179062..179064,
179074..179076,179206..179208,179233..179235)
/gene="fhuB"
/locus_tag="ECOK1_0156"
/note="putative PBP binding regions; other site"
/db_xref="CDD:119348"
gene complement(179339..180619)
/gene="hemL"
/locus_tag="ECOK1_0157"
/db_xref="GeneID:12688725"
CDS complement(179339..180619)
/gene="hemL"
/locus_tag="ECOK1_0157"
/EC_number="5.4.3.8"
/note="identified by similarity to SP:P23893; match to
protein family HMM PF00202; match to protein family HMM
TIGR00713"
/codon_start=1
/transl_table=11
/product="glutamate-1-semialdehyde-2,1-aminomutase"
/protein_id="YP_006099412.1"
/db_xref="GI:386597906"
/db_xref="GeneID:12688725"
/translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTEL
VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
GQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVEPDLTCLGKIIGGGMPVGAF
GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEG
LREAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVY
LAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL"
misc_feature complement(179342..180619)
/gene="hemL"
/locus_tag="ECOK1_0157"
/note="glutamate-1-semialdehyde aminotransferase;
Provisional; Region: PRK00062"
/db_xref="CDD:234607"
misc_feature complement(179351..180601)
/gene="hemL"
/locus_tag="ECOK1_0157"
/note="Acetyl ornithine aminotransferase family. This
family belongs to pyridoxal phosphate (PLP)-dependent
aspartate aminotransferase superfamily (fold I). The major
groups in this CD correspond to ornithine
aminotransferase, acetylornithine aminotransferase;
Region: OAT_like; cd00610"
/db_xref="CDD:99735"
misc_feature complement(order(179825..179827,179900..179905,
179909..179911,180008..180010,180185..180187,
180191..180196,180272..180280))
/gene="hemL"
/locus_tag="ECOK1_0157"
/note="inhibitor-cofactor binding pocket; inhibition site"
/db_xref="CDD:99735"
misc_feature complement(order(179825..179827,179900..179902,
179909..179911,180008..180010,180191..180196,
180272..180277))
/gene="hemL"
/locus_tag="ECOK1_0157"
/note="pyridoxal 5'-phosphate binding site [chemical
binding]; other site"
/db_xref="CDD:99735"
misc_feature complement(179825..179827)
/gene="hemL"
/locus_tag="ECOK1_0157"
/note="catalytic residue [active]"
/db_xref="CDD:99735"
gene 180844..182265
/gene="clcA"
/locus_tag="ECOK1_0158"
/db_xref="GeneID:12688726"
CDS 180844..182265
/gene="clcA"
/locus_tag="ECOK1_0158"
/note="identified by match to protein family HMM PF00654"
/codon_start=1
/transl_table=11
/product="H(+)/Cl(-) exchange transporter ClcA"
/protein_id="YP_006099413.1"
/db_xref="GI:386597907"
/db_xref="GeneID:12688726"
/translation="MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGT
LVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAP
EAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
MVLDVFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAV
FIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGM
QDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLV
FIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIA
GMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILA
RTLAKQEAEQLARSKAASARENT"
misc_feature 181000..182232
/gene="clcA"
/locus_tag="ECOK1_0158"
/note="Chloride channel protein EriC [Inorganic ion
transport and metabolism]; Region: EriC; COG0038"
/db_xref="CDD:30387"
misc_feature 181000..182193
/gene="clcA"
/locus_tag="ECOK1_0158"
/note="ClC chloride channel EriC. This domain is found in
the EriC chloride transporters that mediate the extreme
acid resistance response in eubacteria and archaea. This
response allows bacteria to survive in the acidic
environments by decarboxylation-linked...; Region: EriC;
cd01031"
/db_xref="CDD:79360"
misc_feature order(181159..181173,181279..181293,181906..181920,
182176..182178)
/gene="clcA"
/locus_tag="ECOK1_0158"
/note="Cl- selectivity filter; other site"
/db_xref="CDD:79360"
misc_feature order(181162..181164,181168..181170,181285..181290,
181906..181914,182176..182178)
/gene="clcA"
/locus_tag="ECOK1_0158"
/note="Cl- binding residues [ion binding]; other site"
/db_xref="CDD:79360"
misc_feature 181285..181287
/gene="clcA"
/locus_tag="ECOK1_0158"
/note="pore gating glutamate residue; other site"
/db_xref="CDD:79360"
misc_feature order(181423..181425,181450..181452,181489..181491,
181510..181512,182050..182052,182059..182061,
182083..182085,182119..182121,182140..182145,
182152..182154)
/gene="clcA"
/locus_tag="ECOK1_0158"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:79360"
misc_feature 181450..181452
/gene="clcA"
/locus_tag="ECOK1_0158"
/note="H+/Cl- coupling transport residue; other site"
/db_xref="CDD:79360"
gene 182347..182691
/locus_tag="ECOK1_0159"
/db_xref="GeneID:12688727"
CDS 182347..182691
/locus_tag="ECOK1_0159"
/note="identified by match to protein family HMM PF01521;
match to protein family HMM TIGR00049"
/codon_start=1
/transl_table=11
/product="iron-sulfur cluster assembly accessory protein
YadR"
/protein_id="YP_006099414.1"
/db_xref="GI:386597908"
/db_xref="GeneID:12688727"
/translation="MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
KSTCGCGSSFSI"
misc_feature 182347..182688
/locus_tag="ECOK1_0159"
/note="iron-sulfur cluster insertion protein ErpA;
Provisional; Region: PRK13623"
/db_xref="CDD:184186"
gene complement(182738..183361)
/locus_tag="ECOK1_0160"
/db_xref="GeneID:12688728"
CDS complement(182738..183361)
/locus_tag="ECOK1_0160"
/note="identified by match to protein family HMM PF03458"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099415.1"
/db_xref="GI:386597909"
/db_xref="GeneID:12688728"
/translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
TIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVRQPRRLPKWMLPVLDAVGLAVFV
GIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR"
misc_feature complement(182741..183361)
/locus_tag="ECOK1_0160"
/note="hypothetical protein; Provisional; Region:
PRK10578"
/db_xref="CDD:182564"
misc_feature complement(183122..183355)
/locus_tag="ECOK1_0160"
/note="UPF0126 domain; Region: UPF0126; pfam03458"
/db_xref="CDD:217571"
misc_feature complement(182882..183094)
/locus_tag="ECOK1_0160"
/note="UPF0126 domain; Region: UPF0126; pfam03458"
/db_xref="CDD:217571"
gene complement(183399..184199)
/gene="btuF"
/locus_tag="ECOK1_0161"
/db_xref="GeneID:12688729"
CDS complement(183399..184199)
/gene="btuF"
/locus_tag="ECOK1_0161"
/note="identified by similarity to SP:P37028; match to
protein family HMM PF01497"
/codon_start=1
/transl_table=11
/product="cobalamin ABC transporter periplasmic
cobalamin-binding protein"
/protein_id="YP_006099416.1"
/db_xref="GI:386597910"
/db_xref="GeneID:12688729"
/translation="MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITP
VGVSSYSDYPPQAQKIGQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGI
KVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGP
DQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD"
misc_feature complement(183402..184181)
/gene="btuF"
/locus_tag="ECOK1_0161"
/note="vitamin B12-transporter protein BtuF; Provisional;
Region: PRK03379"
/db_xref="CDD:179575"
misc_feature complement(183420..184127)
/gene="btuF"
/locus_tag="ECOK1_0161"
/note="Cobalamin binding protein BtuF. These proteins
have been shown to function as initial receptors in ABC
transport of vitamin B12 (cobalamin) in eubacterial and
some archaeal species. They belong to the TroA
superfamily of helical backbone metal receptor...; Region:
BtuF; cd01144"
/db_xref="CDD:29747"
misc_feature complement(order(183612..183614,183696..183698,
183939..183941,183945..183947,184050..184052,
184104..184109))
/gene="btuF"
/locus_tag="ECOK1_0161"
/note="cobalamin binding residues [chemical binding];
other site"
/db_xref="CDD:29747"
misc_feature complement(order(183594..183596,183984..183986))
/gene="btuF"
/locus_tag="ECOK1_0161"
/note="putative BtuC binding residues; other site"
/db_xref="CDD:29747"
misc_feature complement(order(183837..183842,183849..183851,
183858..183863,183867..183869,183876..183878,
183888..183890,183906..183908,183915..183917,
183942..183944))
/gene="btuF"
/locus_tag="ECOK1_0161"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:29747"
gene complement(184192..184890)
/gene="mtnN"
/locus_tag="ECOK1_0162"
/db_xref="GeneID:12688730"
CDS complement(184192..184890)
/gene="mtnN"
/locus_tag="ECOK1_0162"
/EC_number="3.2.2.16"
/EC_number="3.2.2.9"
/note="identified by similarity to SP:P0AF15; match to
protein family HMM PF01048; match to protein family HMM
TIGR01704"
/codon_start=1
/transl_table=11
/product="MTA/SAH nucleosidase"
/protein_id="YP_006099417.1"
/db_xref="GI:386597911"
/db_xref="GeneID:12688730"
/translation="MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVA
LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADV
TAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
SLMVESLVQKLAHG"
misc_feature complement(184201..184890)
/gene="mtnN"
/locus_tag="ECOK1_0162"
/note="5'-methylthioadenosine/S-adenosylhomocysteine
nucleosidase; Validated; Region: PRK05584"
/db_xref="CDD:180148"
misc_feature complement(184204..184887)
/gene="mtnN"
/locus_tag="ECOK1_0162"
/note="5'-methylthioadenosine/S-adenosylhomocysteine
nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704"
/db_xref="CDD:130765"
gene 184974..186491
/gene="dgt"
/locus_tag="ECOK1_0163"
/db_xref="GeneID:12688731"
CDS 184974..186491
/gene="dgt"
/locus_tag="ECOK1_0163"
/EC_number="3.1.5.1"
/note="identified by similarity to SP:P15723; match to
protein family HMM PF01966; match to protein family HMM
TIGR01353"
/codon_start=1
/transl_table=11
/product="deoxyguanosinetriphosphate triphosphohydrolase"
/protein_id="YP_006099418.1"
/db_xref="GI:386597912"
/db_xref="GeneID:12688731"
/translation="MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDEL
TGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAAL
RLRDGEEPLNALRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
RGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVAD
LEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFM
YLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFS
HPDVEQLELQGYRVISGLLEIYRPLLNLPLSDFTELVEKERVKRFPIETRLFHKLSTR
HRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ"
misc_feature 184974..186485
/gene="dgt"
/locus_tag="ECOK1_0163"
/note="deoxyguanosinetriphosphate triphosphohydrolase;
Provisional; Region: dgt; PRK04926"
/db_xref="CDD:235320"
misc_feature 185163..>185357
/gene="dgt"
/locus_tag="ECOK1_0163"
/note="Metal dependent phosphohydrolases with conserved
'HD' motif; Region: HDc; cd00077"
/db_xref="CDD:238032"
misc_feature order(185178..185180,185322..185327)
/gene="dgt"
/locus_tag="ECOK1_0163"
/note="Zn2+ binding site [ion binding]; other site"
/db_xref="CDD:238032"
misc_feature 185325..185327
/gene="dgt"
/locus_tag="ECOK1_0163"
/note="Mg2+ binding site [ion binding]; other site"
/db_xref="CDD:238032"
misc_feature 186108..186470
/gene="dgt"
/locus_tag="ECOK1_0163"
/note="Phosphohydrolase-associated domain; Region:
HD_assoc; pfam13286"
/db_xref="CDD:222025"
gene 186621..188045
/gene="degP"
/locus_tag="ECOK1_0164"
/db_xref="GeneID:12688732"
CDS 186621..188045
/gene="degP"
/locus_tag="ECOK1_0164"
/EC_number="3.4.21.-"
/note="identified by similarity to SP:P09376; match to
protein family HMM PF00089; match to protein family HMM
PF00595; match to protein family HMM TIGR02037"
/codon_start=1
/transl_table=11
/product="protease Do"
/protein_id="YP_006099419.1"
/db_xref="GI:386597913"
/db_xref="GeneID:12688732"
/translation="MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPM
LEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGLGGN
GGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNA
ENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNL
TSQMVEYGQVKRGELGIMGTELNSDLAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGD
VITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSST
IFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKV
LDSKPSVLALNIQRGDSTIYLLMQ"
misc_feature 186726..188042
/gene="degP"
/locus_tag="ECOK1_0164"
/note="serine endoprotease; Provisional; Region: PRK10942"
/db_xref="CDD:236802"
misc_feature 186960..187370
/gene="degP"
/locus_tag="ECOK1_0164"
/note="Trypsin-like peptidase domain; Region: Trypsin_2;
pfam13365"
/db_xref="CDD:222077"
misc_feature 187491..187754
/gene="degP"
/locus_tag="ECOK1_0164"
/note="PDZ domain of tryspin-like serine proteases, such
as DegP/HtrA, which are oligomeric proteins involved in
heat-shock response, chaperone function, and apoptosis.
May be responsible for substrate recognition and/or
binding, as most PDZ domains bind...; Region:
PDZ_serine_protease; cd00987"
/db_xref="CDD:238487"
misc_feature order(187491..187499,187503..187505,187656..187661,
187668..187673)
/gene="degP"
/locus_tag="ECOK1_0164"
/note="protein binding site [polypeptide binding]; other
site"
/db_xref="CDD:238487"
misc_feature 187818..188033
/gene="degP"
/locus_tag="ECOK1_0164"
/note="PDZ domain of tryspin-like serine proteases, such
as DegP/HtrA, which are oligomeric proteins involved in
heat-shock response, chaperone function, and apoptosis.
May be responsible for substrate recognition and/or
binding, as most PDZ domains bind...; Region:
PDZ_serine_protease; cd00987"
/db_xref="CDD:238487"
gene 188223..189353
/gene="cdaR"
/locus_tag="ECOK1_0165"
/db_xref="GeneID:12688733"
CDS 188223..189353
/gene="cdaR"
/locus_tag="ECOK1_0165"
/note="identified by similarity to SP:P37047; match to
protein family HMM PF05651"
/codon_start=1
/transl_table=11
/product="carbohydrate diacid regulator"
/protein_id="YP_006099420.1"
/db_xref="GI:386597914"
/db_xref="GeneID:12688733"
/translation="MAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALL
VLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLRKYGELVCMT
AEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDLNQPRVVAIV
EVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNSFGRWDAEDH
RKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQRMPESRCYF
YQDLMLPVLLDSLRGDWQANELARPLARLKAMDNNGLLRRTLAAWFRHNVQPLATSKA
LFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER"
misc_feature 188223..189350
/gene="cdaR"
/locus_tag="ECOK1_0165"
/note="carbohydrate diacid transcriptional activator CdaR;
Provisional; Region: PRK11477"
/db_xref="CDD:183155"
misc_feature 188223..188615
/gene="cdaR"
/locus_tag="ECOK1_0165"
/note="Putative sugar diacid recognition; Region:
Diacid_rec; pfam05651"
/db_xref="CDD:147680"
misc_feature 189171..189338
/gene="cdaR"
/locus_tag="ECOK1_0165"
/note="PucR C-terminal helix-turn-helix domain; Region:
HTH_30; pfam13556"
/db_xref="CDD:205734"
gene complement(189407..189793)
/locus_tag="ECOK1_0166"
/db_xref="GeneID:12688734"
CDS complement(189407..189793)
/locus_tag="ECOK1_0166"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099421.1"
/db_xref="GI:386597915"
/db_xref="GeneID:12688734"
/translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAK
SVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILD
DLRHLESVVTNKISEIEADLEKLTRK"
misc_feature complement(189419..189793)
/locus_tag="ECOK1_0166"
/note="hypothetical protein; Provisional; Region:
PRK13677"
/db_xref="CDD:184234"
gene complement(190105..190929)
/gene="dapD"
/locus_tag="ECOK1_0167"
/db_xref="GeneID:12688735"
CDS complement(190105..190929)
/gene="dapD"
/locus_tag="ECOK1_0167"
/EC_number="2.3.1.117"
/note="identified by similarity to SP:P56220; match to
protein family HMM PF00132; match to protein family HMM
TIGR00965"
/codon_start=1
/transl_table=11
/product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
N-succinyltransferase"
/protein_id="YP_006099422.1"
/db_xref="GI:386597916"
/db_xref="GeneID:12688735"
/translation="MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALR
VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFANYDEARFQKEG
FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRE
TGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
misc_feature complement(190117..190929)
/gene="dapD"
/locus_tag="ECOK1_0167"
/note="2,3,4,5-tetrahydropyridine-2,6-carboxylate
N-succinyltransferase; Provisional; Region: dapD;
PRK11830"
/db_xref="CDD:236996"
misc_feature complement(190213..190626)
/gene="dapD"
/locus_tag="ECOK1_0167"
/note="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP)
N-succinyltransferase (also called THP
succinyltransferase): THDP N-succinyltransferase catalyzes
the conversion of tetrahydrodipicolinate and succinyl-CoA
to N-succinyltetrahydrodipicolinate and CoA; Region:
LbH_THP_succinylT; cd03350"
/db_xref="CDD:100041"
misc_feature complement(order(190213..190215,190219..190230,
190309..190311,190363..190365,190369..190371,
190447..190449,190495..190503,190549..190551,
190555..190557,190603..190608,190615..190620))
/gene="dapD"
/locus_tag="ECOK1_0167"
/note="trimer interface [polypeptide binding]; other site"
/db_xref="CDD:100041"
misc_feature complement(order(190318..190323,190354..190356,
190369..190377,190414..190416,190423..190428,
190432..190434,190453..190455,190459..190461,
190486..190488,190507..190509,190543..190545,
190558..190560,190594..190596,190618..190620))
/gene="dapD"
/locus_tag="ECOK1_0167"
/note="active site"
/db_xref="CDD:100041"
misc_feature complement(order(190426..190428,190486..190488,
190507..190509,190543..190545,190558..190560,
190594..190596,190618..190620))
/gene="dapD"
/locus_tag="ECOK1_0167"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:100041"
misc_feature complement(order(190318..190323,190354..190356,
190369..190377,190414..190416,190432..190434,
190450..190455))
/gene="dapD"
/locus_tag="ECOK1_0167"
/note="CoA binding site [chemical binding]; other site"
/db_xref="CDD:100041"
gene complement(190960..193632)
/gene="glnD"
/locus_tag="ECOK1_0168"
/db_xref="GeneID:12688736"
CDS complement(190960..193632)
/gene="glnD"
/locus_tag="ECOK1_0168"
/EC_number="2.7.7.59"
/note="identified by similarity to SP:P27249; match to
protein family HMM PF01842; match to protein family HMM
PF01909; match to protein family HMM PF01966; match to
protein family HMM PF08335; match to protein family HMM
TIGR01693"
/codon_start=1
/transl_table=11
/product="protein-P-II uridylyltransferase"
/protein_id="YP_006099423.1"
/db_xref="GI:386597917"
/db_xref="GeneID:12688736"
/translation="MNTLPEQYANTALPTLSGQPQNPCAWPRDELTVGGIKAHIDTFQ
RWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHP
LSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFAL
HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLF
DEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGI
YSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQ
WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIF
IAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
DIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAW
HARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
FTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHF
TVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVED
LFIIATADRRALNNELQQEVHQRLTEALNPNDKG"
misc_feature complement(190963..193614)
/gene="glnD"
/locus_tag="ECOK1_0168"
/note="PII uridylyl-transferase; Provisional; Region:
PRK05007"
/db_xref="CDD:179913"
misc_feature complement(193084..193482)
/gene="glnD"
/locus_tag="ECOK1_0168"
/note="Nucleotidyltransferase (NT) domain of Escherichia
coli adenylyltransferase (GlnE), Escherichia coli uridylyl
transferase (GlnD), and similar proteins; Region:
NT_GlnE_GlnD_like; cd05401"
/db_xref="CDD:143391"
misc_feature complement(order(193234..193236,193312..193314,
193318..193320))
/gene="glnD"
/locus_tag="ECOK1_0168"
/note="metal binding triad; metal-binding site"
/db_xref="CDD:143391"
misc_feature complement(192640..193059)
/gene="glnD"
/locus_tag="ECOK1_0168"
/note="GlnD PII-uridylyltransferase; Region:
GlnD_UR_UTase; pfam08335"
/db_xref="CDD:149407"
misc_feature complement(191779..192237)
/gene="glnD"
/locus_tag="ECOK1_0168"
/note="Metal dependent phosphohydrolases with conserved
'HD' motif; Region: HDc; cd00077"
/db_xref="CDD:28958"
misc_feature complement(order(191842..191844,192088..192093,
192220..192222))
/gene="glnD"
/locus_tag="ECOK1_0168"
/note="Zn2+ binding site [ion binding]; other site"
/db_xref="CDD:28958"
misc_feature complement(192088..192090)
/gene="glnD"
/locus_tag="ECOK1_0168"
/note="Mg2+ binding site [ion binding]; other site"
/db_xref="CDD:28958"
misc_feature complement(191299..191514)
/gene="glnD"
/locus_tag="ECOK1_0168"
/note="ACT domain family, ACT_UUR-like_1, includes the
first of two C-terminal ACT domains of the bacterial
signal-transducing uridylyltransferase /uridylyl-removing
(UUR) enzyme, GlnD and related domains; Region:
ACT_UUR-like_1; cd04900"
/db_xref="CDD:153172"
misc_feature complement(190981..191184)
/gene="glnD"
/locus_tag="ECOK1_0168"
/note="C-terminal ACT domains of the bacterial
signal-transducing uridylyltransferase /uridylyl-removing
(UUR) enzyme, GlnD and related domains; Region:
ACT_ACR-UUR-like_2; cd04899"
/db_xref="CDD:153171"
gene complement(193694..194488)
/gene="map"
/locus_tag="ECOK1_0169"
/db_xref="GeneID:12688737"
CDS complement(193694..194488)
/gene="map"
/locus_tag="ECOK1_0169"
/EC_number="3.4.11.18"
/note="identified by match to protein family HMM PF00557;
match to protein family HMM TIGR00500"
/codon_start=1
/transl_table=11
/product="methionine aminopeptidase"
/protein_id="YP_006099424.1"
/db_xref="GI:386597918"
/db_xref="GeneID:12688737"
/translation="MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRI
CNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIK
DGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMK
DGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE"
misc_feature complement(193739..194458)
/gene="map"
/locus_tag="ECOK1_0169"
/note="Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also
known as methionyl aminopeptidase and Peptidase M.
Catalyzes release of N-terminal amino acids,
preferentially methionine, from peptides and arylamides;
Region: MetAP1; cd01086"
/db_xref="CDD:238519"
misc_feature complement(order(193784..193786,193877..193879,
193976..193978,194165..194167,194198..194200,
194252..194254))
/gene="map"
/locus_tag="ECOK1_0169"
/note="active site"
/db_xref="CDD:238519"
gene 194856..195581
/gene="rpsB"
/locus_tag="ECOK1_0170"
/db_xref="GeneID:12688738"
CDS 194856..195581
/gene="rpsB"
/locus_tag="ECOK1_0170"
/note="identified by match to protein family HMM PF00318;
match to protein family HMM TIGR01011"
/codon_start=1
/transl_table=11
/product="30S ribosomal protein S2"
/protein_id="YP_006099425.1"
/db_xref="GI:386597919"
/db_xref="GeneID:12688738"
/translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
KTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
NWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVA
ATVREGRSQDLASQAEESFVEAE"
misc_feature 194880..195524
/gene="rpsB"
/locus_tag="ECOK1_0170"
/note="Ribosomal protein S2 (RPS2), involved in formation
of the translation initiation complex, where it might
contact the messenger RNA and several components of the
ribosome. It has been shown that in Escherichia coli RPS2
is essential for the binding of...; Region: RPS2; cd01425"
/db_xref="CDD:100106"
misc_feature order(194928..194933,194958..194966,195138..195140,
195144..195152,195159..195164,195378..195380,
195387..195389)
/gene="rpsB"
/locus_tag="ECOK1_0170"
/note="rRNA interaction site [nucleotide binding]; other
site"
/db_xref="CDD:100106"
misc_feature order(195384..195389,195393..195395,195435..195446)
/gene="rpsB"
/locus_tag="ECOK1_0170"
/note="S8 interaction site; other site"
/db_xref="CDD:100106"
misc_feature 195489..195506
/gene="rpsB"
/locus_tag="ECOK1_0170"
/note="putative laminin-1 binding site; other site"
/db_xref="CDD:100106"
gene 195716..196567
/gene="tsf"
/locus_tag="ECOK1_0171"
/db_xref="GeneID:12688739"
CDS 195716..196567
/gene="tsf"
/locus_tag="ECOK1_0171"
/note="identified by match to protein family HMM PF00627;
match to protein family HMM PF00889; match to protein
family HMM TIGR00116"
/codon_start=1
/transl_table=11
/product="translation elongation factor Ts"
/protein_id="YP_006099426.1"
/db_xref="GI:386597920"
/db_xref="GeneID:12688739"
/translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
GAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVA
GKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
RMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEV
AAMSKQS"
misc_feature 195716..196558
/gene="tsf"
/locus_tag="ECOK1_0171"
/note="elongation factor Ts; Provisional; Region: tsf;
PRK09377"
/db_xref="CDD:236491"
misc_feature 195725..195832
/gene="tsf"
/locus_tag="ECOK1_0171"
/note="UBA/TS-N domain; Region: UBA; pfam00627"
/db_xref="CDD:201355"
misc_feature 195896..>196003
/gene="tsf"
/locus_tag="ECOK1_0171"
/note="Elongation factor TS; Region: EF_TS; pfam00889"
/db_xref="CDD:189759"
misc_feature 196124..196504
/gene="tsf"
/locus_tag="ECOK1_0171"
/note="Elongation factor TS; Region: EF_TS; pfam00889"
/db_xref="CDD:189759"
gene 196714..197439
/gene="pyrH"
/locus_tag="ECOK1_0172"
/db_xref="GeneID:12688740"
CDS 196714..197439
/gene="pyrH"
/locus_tag="ECOK1_0172"
/EC_number="2.7.4.22"
/note="identified by similarity to SP:P0A7E9; match to
protein family HMM PF00696; match to protein family HMM
TIGR02075"
/codon_start=1
/transl_table=11
/product="UMP kinase"
/protein_id="YP_006099427.1"
/db_xref="GI:386597921"
/db_xref="GeneID:12688740"
/translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
RLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVF
NMNKPGALRRVVMGEKEGTLITE"
misc_feature 196741..197433
/gene="pyrH"
/locus_tag="ECOK1_0172"
/note="UMP kinase (UMPK)-Ec, the microbial/chloroplast
uridine monophosphate kinase (uridylate kinase) enzyme
that catalyzes UMP phosphorylation and plays a key role in
pyrimidine nucleotide biosynthesis; regulation of this
process is via feed-back control and...; Region:
AAK_UMPK-PyrH-Ec; cd04254"
/db_xref="CDD:239787"
misc_feature order(196756..196758,196765..196770,196879..196887,
197146..197151,197206..197211,197218..197220,
197224..197226,197230..197235)
/gene="pyrH"
/locus_tag="ECOK1_0172"
/note="putative nucleotide binding site [chemical
binding]; other site"
/db_xref="CDD:239787"
misc_feature order(196879..196887,196897..196902,196942..196944,
196951..196956,197125..197127,197131..197136,
197140..197148)
/gene="pyrH"
/locus_tag="ECOK1_0172"
/note="uridine monophosphate binding site [chemical
binding]; other site"
/db_xref="CDD:239787"
misc_feature order(196918..196923,196945..196950,196969..196971,
196990..196992,197020..197022,197062..197064,
197074..197076,197083..197085,197101..197103,
197125..197127,197131..197139,197164..197166,
197173..197178,197344..197346)
/gene="pyrH"
/locus_tag="ECOK1_0172"
/note="homohexameric interface [polypeptide binding];
other site"
/db_xref="CDD:239787"
gene 197589..198146
/gene="frr"
/locus_tag="ECOK1_0173"
/db_xref="GeneID:12688741"
CDS 197589..198146
/gene="frr"
/locus_tag="ECOK1_0173"
/note="identified by match to protein family HMM PF01765;
match to protein family HMM TIGR00496"
/codon_start=1
/transl_table=11
/product="ribosome recycling factor"
/protein_id="YP_006099428.1"
/db_xref="GI:386597922"
/db_xref="GeneID:12688741"
/translation="MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEY
YGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPL
PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
QKLTDAAIKKIEAALADKEAELMQF"
misc_feature 197589..198143
/gene="frr"
/locus_tag="ECOK1_0173"
/note="ribosome recycling factor; Reviewed; Region: frr;
PRK00083"
/db_xref="CDD:178850"
misc_feature 197601..198137
/gene="frr"
/locus_tag="ECOK1_0173"
/note="Ribosome recycling factor (RRF). Ribosome recycling
factor dissociates the posttermination complex, composed
of the ribosome, deacylated tRNA, and mRNA, after
termination of translation. Thus ribosomes are 'recycled'
and ready for another...; Region: RRF; cd00520"
/db_xref="CDD:238288"
misc_feature order(197673..197684,197892..197903)
/gene="frr"
/locus_tag="ECOK1_0173"
/note="hinge region; other site"
/db_xref="CDD:238288"
gene 198238..199434
/gene="dxr"
/locus_tag="ECOK1_0174"
/db_xref="GeneID:12688742"
CDS 198238..199434
/gene="dxr"
/locus_tag="ECOK1_0174"
/EC_number="1.1.1.267"
/note="identified by similarity to SP:P45568; match to
protein family HMM PF02670; match to protein family HMM
PF08436; match to protein family HMM TIGR00243"
/codon_start=1
/transl_table=11
/product="1-deoxy-D-xylulose 5-phosphate reductoisomerase"
/protein_id="YP_006099429.1"
/db_xref="GI:386597923"
/db_xref="GeneID:12688742"
/translation="MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVARMVE
QCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIV
GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL
PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKI
SVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
RTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTA
LNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDANAREVARKE
VMRLAS"
misc_feature 198238..199431
/gene="dxr"
/locus_tag="ECOK1_0174"
/note="1-deoxy-D-xylulose 5-phosphate reductoisomerase;
Provisional; Region: PRK05447"
/db_xref="CDD:180089"
misc_feature 198247..198633
/gene="dxr"
/locus_tag="ECOK1_0174"
/note="1-deoxy-D-xylulose 5-phosphate reductoisomerase;
Region: DXP_reductoisom; pfam02670"
/db_xref="CDD:202340"
misc_feature 198673..198954
/gene="dxr"
/locus_tag="ECOK1_0174"
/note="1-deoxy-D-xylulose 5-phosphate reductoisomerase
C-terminal; Region: DXP_redisom_C; pfam08436"
/db_xref="CDD:203943"
misc_feature 199051..199404
/gene="dxr"
/locus_tag="ECOK1_0174"
/note="DXP reductoisomerase C-terminal domain; Region:
DXPR_C; pfam13288"
/db_xref="CDD:205468"
gene 199623..200381
/gene="uppS"
/locus_tag="ECOK1_0175"
/db_xref="GeneID:12688743"
CDS 199623..200381
/gene="uppS"
/locus_tag="ECOK1_0175"
/EC_number="2.5.1.31"
/note="identified by match to protein family HMM PF01255;
match to protein family HMM TIGR00055"
/codon_start=1
/transl_table=11
/product="di-trans,poly-cis-decaprenylcistransferase"
/protein_id="YP_006099430.1"
/db_xref="GI:386597924"
/db_xref="GeneID:12688743"
/translation="MLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
GAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEK
VQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
LWPDFDEQDFEGALNAFANRERRFGGTEPGDETA"
misc_feature 199623..200357
/gene="uppS"
/locus_tag="ECOK1_0175"
/note="Undecaprenyl pyrophosphate synthase [Lipid
metabolism]; Region: UppS; COG0020"
/db_xref="CDD:223099"
misc_feature 199671..200333
/gene="uppS"
/locus_tag="ECOK1_0175"
/note="Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS);
homodimers which catalyze the successive 1'-4 condensation
of the isopentenyl diphosphate (IPP) molecule to
trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP
to form long-chain polyprenyl...; Region: CIS_IPPS;
cd00475"
/db_xref="CDD:238265"
misc_feature 199695..199697
/gene="uppS"
/locus_tag="ECOK1_0175"
/note="catalytic residue [active]"
/db_xref="CDD:238265"
misc_feature 199698..199709
/gene="uppS"
/locus_tag="ECOK1_0175"
/note="putative FPP diphosphate binding site; other site"
/db_xref="CDD:238265"
misc_feature order(199818..199832,199872..199877,199881..199889,
199968..199970,199989..199991,200034..200036,
200040..200042)
/gene="uppS"
/locus_tag="ECOK1_0175"
/note="putative FPP binding hydrophobic cleft; other site"
/db_xref="CDD:238265"
misc_feature order(200061..200063,200085..200087,200097..200099,
200106..200108,200133..200135,200214..200219,
200226..200228,200238..200240,200247..200249,
200259..200261)
/gene="uppS"
/locus_tag="ECOK1_0175"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:238265"
misc_feature order(200199..200201,200217..200219)
/gene="uppS"
/locus_tag="ECOK1_0175"
/note="putative IPP diphosphate binding site; other site"
/db_xref="CDD:238265"
gene 200394..201251
/gene="cdsA"
/locus_tag="ECOK1_0176"
/db_xref="GeneID:12688744"
CDS 200394..201251
/gene="cdsA"
/locus_tag="ECOK1_0176"
/EC_number="2.7.7.41"
/note="identified by match to protein family HMM PF01148"
/codon_start=1
/transl_table=11
/product="phosphatidate cytidylyltransferase"
/protein_id="YP_006099431.1"
/db_xref="GI:386597925"
/db_xref="GeneID:12688744"
/translation="MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWG
QLSGFTTRSQRVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLL
VLFYPGSAAIWRNSKTLRIIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLVTAAVISWGYGMWVNLDVAPV
TLLICSIVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
LLLLVFRTL"
misc_feature 200394..201248
/gene="cdsA"
/locus_tag="ECOK1_0176"
/note="CDP-diglyceride synthase; Provisional; Region:
cdsA; PRK11624"
/db_xref="CDD:183240"
gene 201263..202615
/gene="rseP"
/locus_tag="ECOK1_0177"
/db_xref="GeneID:12688745"
CDS 201263..202615
/gene="rseP"
/locus_tag="ECOK1_0177"
/EC_number="3.4.24.-"
/note="identified by similarity to SP:P37764; match to
protein family HMM PF00595; match to protein family HMM
PF02163; match to protein family HMM TIGR00054"
/codon_start=1
/transl_table=11
/product="RIP metalloprotease RseP"
/protein_id="YP_006099432.1"
/db_xref="GI:386597926"
/db_xref="GeneID:12688745"
/translation="MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGF
GKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIA
AGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPR
GPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEI
ERQGSPLSLTLIPESKPGKGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKT
WQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGI
INLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
"
misc_feature 201266..202612
/gene="rseP"
/locus_tag="ECOK1_0177"
/note="zinc metallopeptidase RseP; Provisional; Region:
PRK10779"
/db_xref="CDD:182723"
misc_feature 201284..>201616
/gene="rseP"
/locus_tag="ECOK1_0177"
/note="RseP-like Site-2 proteases (S2P), zinc
metalloproteases (MEROPS family M50A), cleave
transmembrane domains of substrate proteins, regulating
intramembrane proteolysis (RIP) of diverse signal
transduction mechanisms. In Escherichia coli, the S2P
homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163"
/db_xref="CDD:100084"
misc_feature order(201326..201331,201338..201340)
/gene="rseP"
/locus_tag="ECOK1_0177"
/note="active site"
/db_xref="CDD:100084"
misc_feature 201893..202129
/gene="rseP"
/locus_tag="ECOK1_0177"
/note="PDZ domain of bacterial and plant zinc
metalloprotases, presumably membrane-associated or
integral membrane proteases, which may be involved in
signalling and regulatory mechanisms. May be responsible
for substrate recognition and/or binding, as most PDZ...;
Region: PDZ_metalloprotease; cd00989"
/db_xref="CDD:238489"
misc_feature order(201896..201907,201911..201913,202040..202045,
202052..202057)
/gene="rseP"
/locus_tag="ECOK1_0177"
/note="protein binding site [polypeptide binding]; other
site"
/db_xref="CDD:238489"
misc_feature <202400..202609
/gene="rseP"
/locus_tag="ECOK1_0177"
/note="RseP-like Site-2 proteases (S2P), zinc
metalloproteases (MEROPS family M50A), cleave
transmembrane domains of substrate proteins, regulating
intramembrane proteolysis (RIP) of diverse signal
transduction mechanisms. In Escherichia coli, the S2P
homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163"
/db_xref="CDD:100084"
misc_feature 202442..202453
/gene="rseP"
/locus_tag="ECOK1_0177"
/note="putative substrate binding region [chemical
binding]; other site"
/db_xref="CDD:100084"
gene 202645..205077
/gene="yaeT"
/locus_tag="ECOK1_0178"
/db_xref="GeneID:12688746"
CDS 202645..205077
/gene="yaeT"
/locus_tag="ECOK1_0178"
/note="identified by match to protein family HMM PF01103;
match to protein family HMM PF07244; match to protein
family HMM TIGR03303"
/codon_start=1
/transl_table=11
/product="outer membrane protein assembly complex, YaeT
protein"
/protein_id="YP_006099433.1"
/db_xref="GI:386597927"
/db_xref="GeneID:12688746"
/translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGN
KSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPR
NRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQK
LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGN
LAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT
VKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRL
GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
GTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKS
YGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFK
TDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDD
HKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNY
DPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWD
MGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDK
AEQFQFNIGKTW"
misc_feature 202645..205074
/gene="yaeT"
/locus_tag="ECOK1_0178"
/note="outer membrane protein assembly factor YaeT;
Provisional; Region: PRK11067"
/db_xref="CDD:236834"
misc_feature 202714..202917
/gene="yaeT"
/locus_tag="ECOK1_0178"
/note="Surface antigen variable number repeat; Region:
Surf_Ag_VNR; pfam07244"
/db_xref="CDD:219346"
misc_feature 202918..203160
/gene="yaeT"
/locus_tag="ECOK1_0178"
/note="Surface antigen variable number repeat; Region:
Surf_Ag_VNR; pfam07244"
/db_xref="CDD:219346"
misc_feature 203167..203433
/gene="yaeT"
/locus_tag="ECOK1_0178"
/note="Surface antigen variable number repeat; Region:
Surf_Ag_VNR; pfam07244"
/db_xref="CDD:219346"
misc_feature 203440..203676
/gene="yaeT"
/locus_tag="ECOK1_0178"
/note="Surface antigen variable number repeat; Region:
Surf_Ag_VNR; pfam07244"
/db_xref="CDD:219346"
misc_feature 203683..203907
/gene="yaeT"
/locus_tag="ECOK1_0178"
/note="Surface antigen variable number repeat; Region:
Surf_Ag_VNR; pfam07244"
/db_xref="CDD:219346"
misc_feature 203986..205074
/gene="yaeT"
/locus_tag="ECOK1_0178"
/note="Surface antigen; Region: Bac_surface_Ag; pfam01103"
/db_xref="CDD:216300"
gene 205199..205684
/gene="skp"
/locus_tag="ECOK1_0179"
/db_xref="GeneID:12688747"
CDS 205199..205684
/gene="skp"
/locus_tag="ECOK1_0179"
/note="identified by similarity to SP:P31519; match to
protein family HMM PF03938"
/codon_start=1
/transl_table=11
/product="chaperone protein Skp"
/protein_id="YP_006099434.1"
/db_xref="GI:386597928"
/db_xref="GeneID:12688747"
/translation="MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSN
TLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFE
QDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQV
K"
misc_feature 205262..205681
/gene="skp"
/locus_tag="ECOK1_0179"
/note="periplasmic chaperone; Provisional; Region:
PRK10780"
/db_xref="CDD:182724"
misc_feature 205268..205681
/gene="skp"
/locus_tag="ECOK1_0179"
/note="Outer membrane protein (OmpH-like); Region: OmpH;
smart00935"
/db_xref="CDD:214922"
gene 205688..206713
/gene="lpxD"
/locus_tag="ECOK1_0180"
/db_xref="GeneID:12688748"
CDS 205688..206713
/gene="lpxD"
/locus_tag="ECOK1_0180"
/EC_number="2.3.1.-"
/note="identified by match to protein family HMM PF00132;
match to protein family HMM PF04613; match to protein
family HMM TIGR01853"
/codon_start=1
/transl_table=11
/product="UDP-3-O-[3-hydroxymyristoyl] glucosamine
N-acyltransferase"
/protein_id="YP_006099435.1"
/db_xref="GI:386597929"
/db_xref="GeneID:12688748"
/translation="MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVN
PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPKPAQNIAP
SAVIDETAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTI
YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRG
ALDDTVIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLE
RKVNQQD"
misc_feature 205733..206707
/gene="lpxD"
/locus_tag="ECOK1_0180"
/note="UDP-3-O-[3-hydroxymyristoyl] glucosamine
N-acyltransferase; Provisional; Region: lpxD; PRK00892"
/db_xref="CDD:179158"
misc_feature 205748..205957
/gene="lpxD"
/locus_tag="ECOK1_0180"
/note="UDP-3-O-[3-hydroxymyristoyl] glucosamine
N-acyltransferase, LpxD; Region: LpxD; pfam04613"
/db_xref="CDD:203056"
misc_feature 206012..206629
/gene="lpxD"
/locus_tag="ECOK1_0180"
/note="UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD):
The enzyme catalyzes the transfer of 3-hydroxymyristic
acid or 3-hydroxy-arachidic acid, depending on the
organism, from the acyl carrier protein (ACP) to
UDP-3-O-acyl-glucosamine to produce UDP-2; Region:
LbH_LpxD; cd03352"
/db_xref="CDD:100043"
misc_feature order(206048..206050,206060..206065,206117..206119,
206156..206158,206162..206164,206168..206170,
206204..206206,206210..206212,206228..206230,
206234..206236,206267..206275,206309..206311,
206321..206323,206327..206329,206333..206335,
206342..206350,206375..206377,206381..206389,
206393..206395,206405..206407,206423..206425,
206429..206431,206441..206449,206477..206479,
206495..206503,206513..206515,206549..206557,
206609..206611,206621..206623)
/gene="lpxD"
/locus_tag="ECOK1_0180"
/note="trimer interface [polypeptide binding]; other site"
/db_xref="CDD:100043"
misc_feature order(206234..206242,206381..206383,206393..206395,
206402..206407,206435..206440,206453..206461,
206510..206515,206546..206548)
/gene="lpxD"
/locus_tag="ECOK1_0180"
/note="active site"
/db_xref="CDD:100043"
misc_feature order(206234..206242,206402..206407,206456..206461,
206510..206515)
/gene="lpxD"
/locus_tag="ECOK1_0180"
/note="UDP-GlcNAc binding site [chemical binding]; other
site"
/db_xref="CDD:100043"
misc_feature order(206381..206383,206393..206395,206435..206440,
206453..206455,206546..206548)
/gene="lpxD"
/locus_tag="ECOK1_0180"
/note="lipid binding site [chemical binding];
lipid-binding site"
/db_xref="CDD:100043"
gene 206818..207273
/gene="fabZ"
/locus_tag="ECOK1_0181"
/db_xref="GeneID:12688749"
CDS 206818..207273
/gene="fabZ"
/locus_tag="ECOK1_0181"
/EC_number="4.2.1.-"
/note="identified by match to protein family HMM PF07977;
match to protein family HMM TIGR01750"
/codon_start=1
/transl_table=11
/product="beta-hydroxyacyl-(acyl-carrier-protein)
dehydratase FabZ"
/protein_id="YP_006099436.1"
/db_xref="GI:386597930"
/db_xref="GeneID:12688749"
/translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
SVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
misc_feature 206866..207255
/gene="fabZ"
/locus_tag="ECOK1_0181"
/note="FabZ is a 17kD beta-hydroxyacyl-acyl carrier
protein (ACP) dehydratase that primarily catalyzes the
dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP,
the third step in the elongation phase of the bacterial/
plastid, type II, fatty-acid...; Region: FabZ; cd01288"
/db_xref="CDD:238615"
gene 207277..208065
/gene="lpxA"
/locus_tag="ECOK1_0182"
/db_xref="GeneID:12688750"
CDS 207277..208065
/gene="lpxA"
/locus_tag="ECOK1_0182"
/EC_number="2.3.1.129"
/note="identified by match to protein family HMM PF00132;
match to protein family HMM TIGR01852"
/codon_start=1
/transl_table=11
/product="acyl-CoA dehydrogenase"
/protein_id="YP_006099437.1"
/db_xref="GI:386597931"
/db_xref="GeneID:12688750"
/translation="MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL
KSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
VQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNA
YKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR"
misc_feature 207286..208062
/gene="lpxA"
/locus_tag="ECOK1_0182"
/note="UDP-N-acetylglucosamine acyltransferase;
Provisional; Region: PRK05289"
/db_xref="CDD:235390"
misc_feature 207298..208056
/gene="lpxA"
/locus_tag="ECOK1_0182"
/note="UDP-N-acetylglucosamine O-acyltransferase
(UDP-GlcNAc acyltransferase): Proteins in this family
catalyze the transfer of (R)-3-hydroxymyristic acid from
its acyl carrier protein thioester to UDP-GlcNAc. It is
the first enzyme in the lipid A biosynthetic...; Region:
LbH_UDP-GlcNAc_AT; cd03351"
/db_xref="CDD:100042"
misc_feature order(207493..207495,207502..207504,207571..207573,
207640..207642,207649..207651,207706..207708,
207754..207759,207793..207795,207868..207870,
207886..207891)
/gene="lpxA"
/locus_tag="ECOK1_0182"
/note="active site"
/db_xref="CDD:100042"
gene 208065..209213
/gene="lpxB"
/locus_tag="ECOK1_0183"
/db_xref="GeneID:12688751"
CDS 208065..209213
/gene="lpxB"
/locus_tag="ECOK1_0183"
/EC_number="2.4.1.182"
/note="identified by match to protein family HMM PF02684;
match to protein family HMM TIGR00215"
/codon_start=1
/transl_table=11
/product="lipid-A-disaccharide synthase"
/protein_id="YP_006099438.1"
/db_xref="GI:386597932"
/db_xref="GeneID:12688751"
/translation="MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGP
RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDF
NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVP
CRFIGHTMADAMPLDPDKNGARDVLGIPYDAHCLALLPGSRGAEVEMLSADFLKTAQL
LRQTYPDLEIVVPLVNAKRREQFERIKAAVAPDLSVHLLDGMGREAMVASDAALLASG
TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEP
QKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ"
misc_feature 208080..209168
/gene="lpxB"
/locus_tag="ECOK1_0183"
/note="lipid-A-disaccharide synthase; Reviewed; Region:
lpxB; PRK00025"
/db_xref="CDD:234580"
misc_feature 208086..209057
/gene="lpxB"
/locus_tag="ECOK1_0183"
/note="ipid-A-disaccharide synthase; Provisional; Region:
PRK14089"
/db_xref="CDD:237606"
gene 209210..209806
/gene="rnhB"
/locus_tag="ECOK1_0184"
/db_xref="GeneID:12688752"
CDS 209210..209806
/gene="rnhB"
/locus_tag="ECOK1_0184"
/EC_number="3.1.26.4"
/note="identified by match to protein family HMM PF01351"
/codon_start=1
/transl_table=11
/product="ribonuclease HII"
/protein_id="YP_006099439.1"
/db_xref="GI:386597933"
/db_xref="GeneID:12688752"
/translation="MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLN
DSKKLSEKRRLVLCEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAP
EYVLIDGNRCPKLPMPSMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS"
misc_feature 209246..209782
/gene="rnhB"
/locus_tag="ECOK1_0184"
/note="bacterial Ribonuclease HII-like; Region:
RNase_HII_bacteria_HII_like; cd07182"
/db_xref="CDD:187695"
misc_feature order(209255..209266,209456..209464,209471..209473,
209531..209533,209570..209572,209627..209629)
/gene="rnhB"
/locus_tag="ECOK1_0184"
/note="RNA/DNA hybrid binding site [nucleotide binding];
other site"
/db_xref="CDD:187695"
misc_feature order(209255..209260,209531..209533,209585..209587)
/gene="rnhB"
/locus_tag="ECOK1_0184"
/note="active site"
/db_xref="CDD:187695"
gene 209843..213325
/gene="dnaE"
/locus_tag="ECOK1_0185"
/db_xref="GeneID:12688753"
CDS 209843..213325
/gene="dnaE"
/locus_tag="ECOK1_0185"
/EC_number="2.7.7.7"
/note="identified by similarity to SP:P10443; match to
protein family HMM PF01336; match to protein family HMM
PF02811; match to protein family HMM PF07733; match to
protein family HMM TIGR00594"
/codon_start=1
/transl_table=11
/product="DNA polymerase III subunit alpha"
/protein_id="YP_006099440.1"
/db_xref="GI:386597934"
/db_xref="GeneID:12688753"
/translation="MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDF
TNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLIS
KAYQRGYGTAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
HFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVA
IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEY
FLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERLKRRPEYDERLDTELQVINQ
MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
HPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNA
GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYG
IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAEL
AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
GLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKG
GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
IERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVML
FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
RGLIGSEQVELEFD"
misc_feature 209855..213295
/gene="dnaE"
/locus_tag="ECOK1_0185"
/note="DNA polymerase III subunit alpha; Validated;
Region: dnaE; PRK05673"
/db_xref="CDD:235554"
misc_feature 209855..210685
/gene="dnaE"
/locus_tag="ECOK1_0185"
/note="Polymerase and Histidinol Phosphatase domain of
alpha-subunit of bacterial polymerase III DnaE1; Region:
PHP_PolIIIA_DnaE1; cd07433"
/db_xref="CDD:213988"
misc_feature order(209870..209872,209876..209878,209897..209899,
209972..209974,210047..210049,210443..210445,
210449..210451)
/gene="dnaE"
/locus_tag="ECOK1_0185"
/note="putative active site [active]"
/db_xref="CDD:213988"
misc_feature order(210014..210016,210026..210034,210644..210646)
/gene="dnaE"
/locus_tag="ECOK1_0185"
/note="putative PHP Thumb interface [polypeptide binding];
other site"
/db_xref="CDD:213988"
misc_feature 212825..213082
/gene="dnaE"
/locus_tag="ECOK1_0185"
/note="DnaE_OBF: A subfamily of OB folds corresponding to
the C-terminal OB-fold nucleic acid binding domain of
Thermus aquaticus and Escherichia coli type C replicative
DNA polymerase III alpha subunit (DnaE). The DNA
polymerase holoenzyme of E. coli contains...; Region:
DnaE_OBF; cd04485"
/db_xref="CDD:239931"
misc_feature order(212825..212827,212981..212983,212987..212989,
212993..212995,213053..213055)
/gene="dnaE"
/locus_tag="ECOK1_0185"
/note="generic binding surface II; other site"
/db_xref="CDD:239931"
misc_feature order(212840..212848,212888..212899,212903..212905,
212921..212929,212933..212935,212978..212980,
212999..213007,213032..213040)
/gene="dnaE"
/locus_tag="ECOK1_0185"
/note="generic binding surface I; other site"
/db_xref="CDD:239931"
gene 213338..214297
/gene="accA"
/locus_tag="ECOK1_0186"
/db_xref="GeneID:12688754"
CDS 213338..214297
/gene="accA"
/locus_tag="ECOK1_0186"
/EC_number="6.4.1.2"
/note="identified by match to protein family HMM PF03255;
match to protein family HMM TIGR00513"
/codon_start=1
/transl_table=11
/product="acetyl-CoA carboxylase, carboxyl transferase
subunit alpha"
/protein_id="YP_006099441.1"
/db_xref="GI:386597935"
/db_xref="GeneID:12688754"
/translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
EKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
GGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
IDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVN
MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
RNPEAMAASLKAQLLTDLADLDVLSTEDLKNRRYQRLMSYGYA"
misc_feature 213338..214291
/gene="accA"
/locus_tag="ECOK1_0186"
/note="acetyl-CoA carboxylase carboxyltransferase subunit
alpha; Validated; Region: PRK05724"
/db_xref="CDD:180223"
misc_feature 213338..214291
/gene="accA"
/locus_tag="ECOK1_0186"
/note="acetyl-CoA carboxylase carboxyltransferase alpha
subunit; Provisional; Region: accA; CHL00198"
/db_xref="CDD:164574"
gene 214395..216536
/gene="ldcC"
/locus_tag="ECOK1_0187"
/note="lysine decarboxylase, constitutive, authentic point
mutation; this gene contains a premature stop which is not
the result of sequencing error; identified by similarity
to SP:P52095; match to protein family HMM PF01276; match
to protein family HMM PF03709; match to protein family HMM
PF03711"
/pseudo
/db_xref="GeneID:12688755"
gene 216593..216982
/locus_tag="ECOK1_0188"
/db_xref="GeneID:12688756"
CDS 216593..216982
/locus_tag="ECOK1_0188"
/note="identified by match to protein family HMM PF00903"
/codon_start=1
/transl_table=11
/product="glyoxylase"
/protein_id="YP_006099442.1"
/db_xref="GI:386597936"
/db_xref="GeneID:12688756"
/translation="MLGLKQVHHIAIIATDYAMSKAFYCDILGFTLQSEVYREARDSW
KGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCEA
IRVDPYTQKRFTFFNDPDGLPLELYEQ"
misc_feature 216602..216976
/locus_tag="ECOK1_0188"
/note="This conserved domain belongs to a superfamily
including the bleomycin resistance protein, glyoxalase I,
and type I ring-cleaving dioxygenases; Region:
Glo_EDI_BRP_like_1; cd08352"
/db_xref="CDD:211358"
misc_feature 216608..216970
/locus_tag="ECOK1_0188"
/note="Glyoxalase/Bleomycin resistance protein/Dioxygenase
superfamily; Region: Glyoxalase; pfam00903"
/db_xref="CDD:216182"
misc_feature order(216617..216619,216824..216826,216965..216967)
/locus_tag="ECOK1_0188"
/note="putative metal binding site [ion binding]; other
site"
/db_xref="CDD:211358"
gene 217047..218345
/gene="tilS"
/locus_tag="ECOK1_0189"
/db_xref="GeneID:12688757"
CDS 217047..218345
/gene="tilS"
/locus_tag="ECOK1_0189"
/EC_number="6.3.4.-"
/note="identified by similarity to SP:P52097; match to
protein family HMM PF01171; match to protein family HMM
PF09179; match to protein family HMM TIGR02432; match to
protein family HMM TIGR02433"
/codon_start=1
/transl_table=11
/product="tRNA(Ile)-lysidine synthase"
/protein_id="YP_006099443.1"
/db_xref="GI:386597937"
/db_xref="GeneID:12688757"
/translation="MTLTLNRQLLSSRQILVAFSGGLDSTVLLHQLVQWRTENPGVTL
RAIHVHHGLSANADAWVKHCENICQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFA
RTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTQLIRPLLARTR
GELVQWALAHGLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAE
QESLLDELLADDLAHCQTPQGTLQIAPMLAMSDARRAAIIRRWLAGQNAPMPSRDALV
RIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKFVTGQSETIVPWQTWLQPLELPA
GLGSVQLTAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRD
TTPLLFYGETLIAAAGVFVTQEGVAVGENGVSFVWKKTLS"
misc_feature 217047..218342
/gene="tilS"
/locus_tag="ECOK1_0189"
/note="tRNA(Ile)-lysidine synthetase; Provisional; Region:
tilS; PRK10660"
/db_xref="CDD:182626"
misc_feature 217086..217613
/gene="tilS"
/locus_tag="ECOK1_0189"
/note="N-terminal domain of predicted ATPase of the
PP-loop faimly implicated in cell cycle control [Cell
division and chromosome partitioning]. This is a subfamily
of Adenine nucleotide alpha hydrolases
superfamily.Adeninosine nucleotide alpha hydrolases...;
Region: PP-ATPase; cd01992"
/db_xref="CDD:30179"
misc_feature order(217098..217106,217110..217121,217188..217190,
217194..217196)
/gene="tilS"
/locus_tag="ECOK1_0189"
/note="Ligand Binding Site [chemical binding]; other site"
/db_xref="CDD:30179"
misc_feature 217767..217973
/gene="tilS"
/locus_tag="ECOK1_0189"
/note="TilS substrate binding domain; Region: TilS;
pfam09179"
/db_xref="CDD:204159"
misc_feature 218112..218327
/gene="tilS"
/locus_tag="ECOK1_0189"
/note="TilS substrate C-terminal domain; Region: TilS_C;
pfam11734"
/db_xref="CDD:204723"
gene complement(218393..218653)
/gene="rof"
/locus_tag="ECOK1_0190"
/db_xref="GeneID:12688758"
CDS complement(218393..218653)
/gene="rof"
/locus_tag="ECOK1_0190"
/note="identified by similarity to SP:P0AFW8; match to
protein family HMM PF07073"
/codon_start=1
/transl_table=11
/product="rof protein"
/protein_id="YP_006099444.1"
/db_xref="GI:386597938"
/db_xref="GeneID:12688758"
/translation="MSINDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASD
LVSRKNVEYLVVEAAGATRELRLDKITSFSHPEIGTVVVSES"
misc_feature complement(218396..218647)
/gene="rof"
/locus_tag="ECOK1_0190"
/note="Rho-binding antiterminator; Provisional; Region:
PRK11625"
/db_xref="CDD:183241"
gene complement(218640..218840)
/locus_tag="ECOK1_0191"
/db_xref="GeneID:12688759"
CDS complement(218640..218840)
/locus_tag="ECOK1_0191"
/note="identified by match to protein family HMM PF06786"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099445.1"
/db_xref="GI:386597939"
/db_xref="GeneID:12688759"
/translation="MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALS
EAVREKAAYAAANLLVSDYVNK"
misc_feature complement(218643..218840)
/locus_tag="ECOK1_0191"
/note="hypothetical protein; Provisional; Region:
PRK04964"
/db_xref="CDD:179901"
gene 219006..219551
/locus_tag="ECOK1_0192"
/db_xref="GeneID:12688760"
CDS 219006..219551
/locus_tag="ECOK1_0192"
/note="identified by similarity to GB:AAN78721.1; match to
protein family HMM PF07152"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099446.1"
/db_xref="GI:386597940"
/db_xref="GeneID:12688760"
/translation="MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRL
LAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEV
ALFAYNSRAAQIWWQQNQSKCAQFANLSVWYLDDEQLAKVSAFADRTMTLQATIQDGV
IWLSDDKNNLEVNLTVWQQPS"
misc_feature 219006..219548
/locus_tag="ECOK1_0192"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG4681"
/db_xref="CDD:227026"
gene 219548..219970
/locus_tag="ECOK1_0193"
/db_xref="GeneID:12688761"
CDS 219548..219970
/locus_tag="ECOK1_0193"
/note="identified by match to protein family HMM PF00472"
/codon_start=1
/transl_table=11
/product="putative peptidyl-tRNA hydrolase"
/protein_id="YP_006099447.1"
/db_xref="GI:386597941"
/db_xref="GeneID:12688761"
/translation="MIVISRHVAIPDGEFEITAIRAQGAGGQHVNKTSTAIHLRFDIR
ASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRNQELNREAALARLVAVIKDLTTEQ
KARRPTRPTRASKERRLASKAQKSSVKAMRGKVRSGRE"
misc_feature 219548..219955
/locus_tag="ECOK1_0193"
/note="hypothetical protein; Provisional; Region:
PRK09256"
/db_xref="CDD:181730"
misc_feature <219551..219967
/locus_tag="ECOK1_0193"
/note="Protein chain release factor B [Translation,
ribosomal structure and biogenesis]; Region: PrfB;
COG1186"
/db_xref="CDD:31379"
gene 219984..220694
/gene="cutF"
/locus_tag="ECOK1_0194"
/db_xref="GeneID:12688762"
CDS 219984..220694
/gene="cutF"
/locus_tag="ECOK1_0194"
/note="identified by match to protein family HMM PF04170"
/codon_start=1
/transl_table=11
/product="copper homeostasis protein CutF"
/protein_id="YP_006099448.1"
/db_xref="GI:386597942"
/db_xref="GeneID:12688762"
/translation="MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS
WRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTD
SKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEPAQSSLPMTPMTLRGMYFYMADAA
TFTDCATGKRFMVANNAELERGYLAARGNSEKPVLLSVEGHFTLEANPDTGAPTKVLA
PDTAGKFYPNQDCSSLGL"
misc_feature 219984..220682
/gene="cutF"
/locus_tag="ECOK1_0194"
/note="lipoprotein involved with copper homeostasis and
adhesion; Provisional; Region: PRK10523"
/db_xref="CDD:236708"
misc_feature 220116..220373
/gene="cutF"
/locus_tag="ECOK1_0194"
/note="NlpE N-terminal domain; Region: NlpE; pfam04170"
/db_xref="CDD:190894"
gene complement(220850..221674)
/locus_tag="ECOK1_0195"
/db_xref="GeneID:12688763"
CDS complement(220850..221674)
/locus_tag="ECOK1_0195"
/note="identified by similarity to GB:ABB60443.1"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099449.1"
/db_xref="GI:386597943"
/db_xref="GeneID:12688763"
/translation="MDKPKAYCRLLLPCFLLLSACTVDISQPDSSATVVNAEAKTWAV
KFQHQSSFTEQSIKEITEPDLKPGDLLFSSSLGVTSFGIRVFSTSSVSHVAIYLGDNN
VAEATGAGVQIVSLKKAIKHSDKLFVLRVPDLTPQQATEITAFANKIKDSGYNYRGIV
EFIPFMVTRQMCSLNPFSEDFRQQCVSGLAKAQLSSVGEGDKKSWFCSEFVTDAFAKA
GHPLTLAQSGWISPADLMHMRSGDVSAFKPETQLQYIGHLKPGIYIKASRFVGLTQ"
misc_feature complement(220853..221674)
/locus_tag="ECOK1_0195"
/note="hypothetical protein; Provisional; Region:
PRK11479"
/db_xref="CDD:183157"
misc_feature complement(<221021..221485)
/locus_tag="ECOK1_0195"
/note="Orthopoxvirus protein of unknown function (DUF830);
Region: DUF830; cl13998"
/db_xref="CDD:209853"
gene complement(221727..223445)
/gene="proS"
/locus_tag="ECOK1_0196"
/db_xref="GeneID:12688764"
CDS complement(221727..223445)
/gene="proS"
/locus_tag="ECOK1_0196"
/EC_number="6.1.1.15"
/note="identified by match to protein family HMM PF00587;
match to protein family HMM PF03129; match to protein
family HMM PF04073; match to protein family HMM TIGR00409"
/codon_start=1
/transl_table=11
/product="prolyl-tRNA synthetase"
/protein_id="YP_006099450.1"
/db_xref="GI:386597944"
/db_xref="GeneID:12688764"
/translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
TGVRVLKKVENIVREEMNNAGAIEVLMPVVQPSELWQESGRWEQYGPELLRIADRGDR
PFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGE
DDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEK
TVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAG
PGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVA
GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
VVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
LDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYL
VKQIKG"
misc_feature complement(221733..223445)
/gene="proS"
/locus_tag="ECOK1_0196"
/note="prolyl-tRNA synthetase; Provisional; Region:
PRK09194"
/db_xref="CDD:236405"
misc_feature complement(<222801..223397)
/gene="proS"
/locus_tag="ECOK1_0196"
/note="Prolyl-tRNA synthetase (ProRS) class II core
catalytic domain. ProRS is a homodimer. It is responsible
for the attachment of proline to the 3' OH group of ribose
of the appropriate tRNA. This domain is primarily
responsible for ATP-dependent...; Region: ProRS_core_prok;
cd00779"
/db_xref="CDD:238402"
misc_feature complement(order(222984..222986,223035..223037,
223095..223097,223149..223163,223167..223169,
223227..223232,223236..223244,223293..223295,
223314..223325,223344..223349))
/gene="proS"
/locus_tag="ECOK1_0196"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:238402"
misc_feature complement(223227..223250)
/gene="proS"
/locus_tag="ECOK1_0196"
/note="motif 1; other site"
/db_xref="CDD:238402"
misc_feature complement(order(222969..222971,222975..222977,
222981..222983,222990..222998,223020..223022,
223026..223028,223113..223115,223119..223121))
/gene="proS"
/locus_tag="ECOK1_0196"
/note="active site"
/db_xref="CDD:238402"
misc_feature complement(223020..223031)
/gene="proS"
/locus_tag="ECOK1_0196"
/note="motif 2; other site"
/db_xref="CDD:238402"
misc_feature complement(222285..222770)
/gene="proS"
/locus_tag="ECOK1_0196"
/note="INS is an amino acid-editing domain inserted (INS)
into the bacterial class II prolyl-tRNA synthetase (ProRS)
however, this CD is not exclusively bacterial. It is also
found at the N-terminus of the eukaryotic/archaea-like
ProRS's of yeasts and...; Region: ProRS-INS; cd04334"
/db_xref="CDD:239826"
misc_feature complement(order(222360..222362,222435..222440,
222609..222611))
/gene="proS"
/locus_tag="ECOK1_0196"
/note="putative deacylase active site [active]"
/db_xref="CDD:239826"
misc_feature complement(222072..>222239)
/gene="proS"
/locus_tag="ECOK1_0196"
/note="Class II tRNA amino-acyl synthetase-like catalytic
core domain. Class II amino acyl-tRNA synthetases (aaRS)
share a common fold and generally attach an amino acid to
the 3' OH of ribose of the appropriate tRNA. PheRS is an
exception in that it...; Region: class_II_aaRS-like_core;
cl00268"
/db_xref="CDD:241739"
misc_feature complement(order(222096..222098,222105..222110,
222114..222119,222207..222209,222219..222224))
/gene="proS"
/locus_tag="ECOK1_0196"
/note="active site"
/db_xref="CDD:238391"
misc_feature complement(order(222096..222098,222105..222107))
/gene="proS"
/locus_tag="ECOK1_0196"
/note="motif 3; other site"
/db_xref="CDD:238391"
misc_feature complement(221745..222029)
/gene="proS"
/locus_tag="ECOK1_0196"
/note="ProRS Prolyl-anticodon binding domain, short
version found predominantly in bacteria. ProRS belongs to
class II aminoacyl-tRNA synthetases (aaRS). This alignment
contains the anticodon binding domain, which is
responsible for specificity in tRNA-binding; Region:
ProRS_anticodon_short; cd00861"
/db_xref="CDD:238438"
misc_feature complement(order(221805..221807,221811..221813,
221841..221843,221865..221867,221883..221885,
222000..222005))
/gene="proS"
/locus_tag="ECOK1_0196"
/note="anticodon binding site; other site"
/db_xref="CDD:238438"
gene complement(223556..224263)
/locus_tag="ECOK1_0197"
/db_xref="GeneID:12688765"
CDS complement(223556..224263)
/locus_tag="ECOK1_0197"
/note="identified by match to protein family HMM PF01980;
match to protein family HMM TIGR00104"
/codon_start=1
/transl_table=11
/product="methyltransferase"
/protein_id="YP_006099451.1"
/db_xref="GI:386597945"
/db_xref="GeneID:12688765"
/translation="MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQ
ADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
SLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
MAVCFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNV
RWRVTDAGFEVFALEPR"
misc_feature complement(223850..224239)
/locus_tag="ECOK1_0197"
/note="Escherichia coli YaeB and related proteins; Region:
UPF0066; cd09281"
/db_xref="CDD:187753"
misc_feature complement(order(223850..223867,223964..223966,
223970..223972,223976..223978,223988..224005,
224078..224080,224090..224092,224111..224113,
224117..224125,224237..224239))
/locus_tag="ECOK1_0197"
/note="homodimer interaction site [polypeptide binding];
other site"
/db_xref="CDD:187753"
misc_feature complement(order(223874..223876,223889..223891,
223958..223960,223964..223966,223988..223990,
224072..224077,224081..224083))
/locus_tag="ECOK1_0197"
/note="cofactor binding site; other site"
/db_xref="CDD:187753"
gene complement(224260..224664)
/gene="rcsF"
/locus_tag="ECOK1_0198"
/db_xref="GeneID:12688766"
CDS complement(224260..224664)
/gene="rcsF"
/locus_tag="ECOK1_0198"
/note="identified by similarity to SP:P69411"
/codon_start=1
/transl_table=11
/product="exopolysaccharide synthesis regulator RcsF"
/protein_id="YP_006099452.1"
/db_xref="GI:386597946"
/db_xref="GeneID:12688766"
/translation="MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAP
RATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKAN
AVLLHSCEVTSGTPGCYRQAVCIGSALNITAK"
misc_feature complement(224266..224664)
/gene="rcsF"
/locus_tag="ECOK1_0198"
/note="outer membrane lipoprotein; Reviewed; Region: rcsF;
PRK10781"
/db_xref="CDD:182725"
gene complement(224782..225597)
/gene="metQ"
/locus_tag="ECOK1_0199"
/db_xref="GeneID:12688767"
CDS complement(224782..225597)
/gene="metQ"
/locus_tag="ECOK1_0199"
/note="identified by similarity to SP:P28635; match to
protein family HMM PF03180; match to protein family HMM
TIGR00363"
/codon_start=1
/transl_table=11
/product="D-methionine ABC transporter substrate-binding
protein"
/protein_id="YP_006099453.1"
/db_xref="GI:386597947"
/db_xref="GeneID:12688767"
/translation="MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQ
VAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDRGYK
LVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
FVEDKESPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
misc_feature complement(224785..225597)
/gene="metQ"
/locus_tag="ECOK1_0199"
/note="DL-methionine transporter substrate-binding
subunit; Provisional; Region: metQ; PRK11063"
/db_xref="CDD:182939"
misc_feature complement(224785..225558)
/gene="metQ"
/locus_tag="ECOK1_0199"
/note="lipoprotein, YaeC family; Region: TIGR00363"
/db_xref="CDD:129460"
gene complement(225637..226290)
/gene="metI"
/locus_tag="ECOK1_0200"
/db_xref="GeneID:12688768"
CDS complement(225637..226290)
/gene="metI"
/locus_tag="ECOK1_0200"
/note="identified by similarity to SP:P31547; match to
protein family HMM PF00528"
/codon_start=1
/transl_table=11
/product="D-methionine ABC transporter permease"
/protein_id="YP_006099454.1"
/db_xref="GI:386597948"
/db_xref="GeneID:12688768"
/translation="MSEPMIWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
QIIANAKLYRTISAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAP
FIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGY
SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK"
misc_feature complement(<225820..226251)
/gene="metI"
/locus_tag="ECOK1_0200"
/note="Transmembrane subunit (TM) found in Periplasmic
Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
transporters which generally bind type 2 PBPs. These types
of transporters consist of a PBP, two TMs, and two
cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
cd06261"
/db_xref="CDD:119394"
misc_feature complement(order(225835..225837,225844..225849,
225889..225891,225940..225942,225949..225954,
225964..225966,225970..225975,225982..225984,
225988..225990,225994..225999,226063..226065,
226069..226074,226081..226110,226114..226125,
226174..226176,226189..226194,226201..226206))
/gene="metI"
/locus_tag="ECOK1_0200"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:119394"
misc_feature complement(226063..226107)
/gene="metI"
/locus_tag="ECOK1_0200"
/note="conserved gate region; other site"
/db_xref="CDD:119394"
misc_feature complement(order(225868..225870,225880..225885,
225901..225939))
/gene="metI"
/locus_tag="ECOK1_0200"
/note="ABC-ATPase subunit interface; other site"
/db_xref="CDD:119394"
gene complement(226283..227314)
/gene="metN"
/locus_tag="ECOK1_0201"
/db_xref="GeneID:12688769"
CDS complement(226283..227314)
/gene="metN"
/locus_tag="ECOK1_0201"
/note="identified by similarity to SP:P30750; match to
protein family HMM PF00005; match to protein family HMM
PF09383; match to protein family HMM TIGR02314"
/codon_start=1
/transl_table=11
/product="D-methionine ABC transporter ATP-binding
protein"
/protein_id="YP_006099455.1"
/db_xref="GI:386597949"
/db_xref="GeneID:12688769"
/translation="MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGK
STLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGN
VALPLELDNTPKDEIKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK
VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQ
SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHH
VKVEVLGYV"
misc_feature complement(226286..227314)
/gene="metN"
/locus_tag="ECOK1_0201"
/note="DL-methionine transporter ATP-binding subunit;
Provisional; Region: metN; PRK11153"
/db_xref="CDD:236863"
misc_feature complement(226616..227314)
/gene="metN"
/locus_tag="ECOK1_0201"
/note="ATP-binding cassette domain of methionine
transporter; Region: ABC_MetN_methionine_transporter;
cd03258"
/db_xref="CDD:213225"
misc_feature complement(227180..227203)
/gene="metN"
/locus_tag="ECOK1_0201"
/note="Walker A/P-loop; other site"
/db_xref="CDD:213225"
misc_feature complement(order(226718..226720,226817..226822,
227048..227050,227177..227185,227189..227194))
/gene="metN"
/locus_tag="ECOK1_0201"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:213225"
misc_feature complement(227048..227059)
/gene="metN"
/locus_tag="ECOK1_0201"
/note="Q-loop/lid; other site"
/db_xref="CDD:213225"
misc_feature complement(226865..226894)
/gene="metN"
/locus_tag="ECOK1_0201"
/note="ABC transporter signature motif; other site"
/db_xref="CDD:213225"
misc_feature complement(226817..226834)
/gene="metN"
/locus_tag="ECOK1_0201"
/note="Walker B; other site"
/db_xref="CDD:213225"
misc_feature complement(226799..226810)
/gene="metN"
/locus_tag="ECOK1_0201"
/note="D-loop; other site"
/db_xref="CDD:213225"
misc_feature complement(226712..226732)
/gene="metN"
/locus_tag="ECOK1_0201"
/note="H-loop/switch region; other site"
/db_xref="CDD:213225"
misc_feature complement(226295..226516)
/gene="metN"
/locus_tag="ECOK1_0201"
/note="This domain is found at the C-terminus of ABC
transporter proteins involved in D-methionine transport as
well as a number of ferredoxin-like proteins; Region: NIL;
smart00930"
/db_xref="CDD:197998"
gene 227502..228074
/locus_tag="ECOK1_0202"
/db_xref="GeneID:12688770"
CDS 227502..228074
/locus_tag="ECOK1_0202"
/note="identified by match to protein family HMM PF08645;
match to protein family HMM TIGR00213; match to protein
family HMM TIGR01656; match to protein family HMM
TIGR01662"
/codon_start=1
/transl_table=11
/product="D,D-heptose 1,7-bisphosphate phosphatase"
/protein_id="YP_006099456.1"
/db_xref="GI:386597950"
/db_xref="GeneID:12688770"
/translation="MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKK
MGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEE
FRQVCDCRKPHPGMFLSARDYLHIDMAASYMVGDKLEDMQAAAAASVGTKVLVRTGKP
ITPEAENAADWVLNSLADLPQAIKKQQKPA"
misc_feature 227514..228044
/locus_tag="ECOK1_0202"
/note="D,D-heptose 1,7-bisphosphate phosphatase; Region:
GmhB_yaeD; TIGR00213"
/db_xref="CDD:129317"
misc_feature 227520..227966
/locus_tag="ECOK1_0202"
/note="Haloacid dehalogenase-like hydrolases. The haloacid
dehalogenase-like (HAD) superfamily includes L-2-haloacid
dehalogenase, epoxide hydrolase, phosphoserine
phosphatase, phosphomannomutase, phosphoglycolate
phosphatase, P-type ATPase, and many others; Region:
HAD_like; cd01427"
/db_xref="CDD:119389"
misc_feature order(227532..227540,227658..227663)
/locus_tag="ECOK1_0202"
/note="active site"
/db_xref="CDD:119389"
misc_feature 227532..227549
/locus_tag="ECOK1_0202"
/note="motif I; other site"
/db_xref="CDD:119389"
misc_feature 227658..227660
/locus_tag="ECOK1_0202"
/note="motif II; other site"
/db_xref="CDD:119389"
gene 228440..229981
/gene="rrsA"
/locus_tag="ECOK1_0203"
/db_xref="GeneID:12688771"
rRNA 228440..229981
/gene="rrsA"
/locus_tag="ECOK1_0203"
/product="16S ribosomal RNA"
/db_xref="GeneID:12688771"
gene 230050..230126
/locus_tag="ECOK1_0204"
/db_xref="GeneID:12688772"
tRNA 230050..230126
/locus_tag="ECOK1_0204"
/product="tRNA-Ile"
/db_xref="GeneID:12688772"
gene 230169..230244
/locus_tag="ECOK1_0205"
/db_xref="GeneID:12688773"
tRNA 230169..230244
/locus_tag="ECOK1_0205"
/product="tRNA-Ala"
/db_xref="GeneID:12688773"
gene 230419..233322
/gene="rrlA"
/locus_tag="ECOK1_0206"
/db_xref="GeneID:12688774"
rRNA 230419..233322
/gene="rrlA"
/locus_tag="ECOK1_0206"
/product="23S ribosomal RNA"
/db_xref="GeneID:12688774"
gene 233421..233540
/gene="rrfA"
/locus_tag="ECOK1_0207"
/db_xref="GeneID:12688775"
rRNA 233421..233540
/gene="rrfA"
/locus_tag="ECOK1_0207"
/product="5S ribosomal RNA"
/db_xref="GeneID:12688775"
gene 233592..233668
/locus_tag="ECOK1_0208"
/db_xref="GeneID:12688776"
tRNA 233592..233668
/locus_tag="ECOK1_0208"
/product="tRNA-Asp"
/db_xref="GeneID:12688776"
gene 233831..234634
/gene="dkgB"
/locus_tag="ECOK1_0210"
/db_xref="GeneID:12688777"
CDS 233831..234634
/gene="dkgB"
/locus_tag="ECOK1_0210"
/EC_number="1.1.1.274"
/note="identified by similarity to SP:P30863; match to
protein family HMM PF00248"
/codon_start=1
/transl_table=11
/product="2,5-didehydrogluconate reductase"
/protein_id="YP_006099457.1"
/db_xref="GI:386597951"
/db_xref="GeneID:12688777"
/translation="MAIPAFGLGTFRLKDDVVISSVKTALELDYRAIDTAQIYDNEAA
VGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPS
DEVSAEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQ
NRKVVAWAKQHGIHITSYMTLAYGNALKDKVIARIAAKHNATPAQVILAWAMGEGYSV
IPSSTKRENLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD"
misc_feature 233837..234580
/gene="dkgB"
/locus_tag="ECOK1_0210"
/note="Aldo-keto reductases (AKRs) are a superfamily of
soluble NAD(P)(H) oxidoreductases whose chief purpose is
to reduce aldehydes and ketones to primary and secondary
alcohols. AKRs are present in all phyla and are of
importance to both health and industrial...; Region:
Aldo_ket_red; cd06660"
/db_xref="CDD:119408"
misc_feature 233843..234583
/gene="dkgB"
/locus_tag="ECOK1_0210"
/note="Aldo/keto reductase family; Region: Aldo_ket_red;
pfam00248"
/db_xref="CDD:215817"
misc_feature order(233855..233863,233930..233932,233945..233947,
234020..234022,234119..234124,234215..234220,
234284..234286,234362..234379,234440..234442,
234485..234496,234509..234511,234518..234523)
/gene="dkgB"
/locus_tag="ECOK1_0210"
/note="active site"
/db_xref="CDD:119408"
misc_feature order(233930..233932,233945..233947,234020..234022,
234119..234121)
/gene="dkgB"
/locus_tag="ECOK1_0210"
/note="catalytic tetrad [active]"
/db_xref="CDD:119408"
gene complement(234631..235545)
/locus_tag="ECOK1_0209"
/db_xref="GeneID:12688778"
CDS complement(234631..235545)
/locus_tag="ECOK1_0209"
/note="identified by match to protein family HMM PF00126;
match to protein family HMM PF03466"
/codon_start=1
/transl_table=11
/product="LysR family transcriptional regulator"
/protein_id="YP_006099458.1"
/db_xref="GI:386597952"
/db_xref="GeneID:12688778"
/translation="MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
LGVSLLNRTTRQLSLTEEGERYFHRVQSILQEMAAAESEIMETRNTPRGLLRIDAATP
VVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
NSYRKIIASPDYISCYGKPETIDDLKQHICLRFTEPASLNTWPIACSDGQLHEVKYGL
SSNSGETLKQLCLSGNGIACLSDYMIDKEIARGELVELMADKVLPVEMPFSAVYYSDR
AVSTRIRAFIDFLSGHVKTAPGGAVREA"
misc_feature complement(234664..235530)
/locus_tag="ECOK1_0209"
/note="Transcriptional regulator [Transcription]; Region:
LysR; COG0583"
/db_xref="CDD:30928"
misc_feature complement(235354..235524)
/locus_tag="ECOK1_0209"
/note="Bacterial regulatory helix-turn-helix protein, lysR
family; Region: HTH_1; pfam00126"
/db_xref="CDD:201021"
misc_feature complement(234679..235275)
/locus_tag="ECOK1_0209"
/note="The C-terminal substrate binding domain of
LysR-type transcriptional regulator CrgA, contains the
type 2 periplasmic binding domain; Region: PBP2_CrgA;
cd08478"
/db_xref="CDD:176167"
misc_feature complement(order(234742..234744,234826..234828,
234877..234879,235060..235062,235066..235068,
235108..235110,235225..235227,235237..235239))
/locus_tag="ECOK1_0209"
/note="putative effector binding pocket; other site"
/db_xref="CDD:176167"
misc_feature complement(order(234850..234852,234859..234864,
234883..234897,234979..234981,235162..235182,
235186..235188,235198..235200,235207..235212,
235216..235221,235231..235236))
/locus_tag="ECOK1_0209"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:176167"
gene 235786..236586
/locus_tag="ECOK1_0211"
/db_xref="GeneID:12688779"
CDS 235786..236586
/locus_tag="ECOK1_0211"
/note="identified by match to protein family HMM PF03372"
/codon_start=1
/transl_table=11
/product="endonuclease/exonuclease/phosphatase family
protein"
/protein_id="YP_006099459.1"
/db_xref="GI:386597953"
/db_xref="GeneID:12688779"
/translation="MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERI
RILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNF
SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTD
DQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK"
misc_feature 235786..236574
/locus_tag="ECOK1_0211"
/note="hypothetical protein; Provisional; Region:
PRK05421"
/db_xref="CDD:235454"
misc_feature order(235933..235935,236014..236016,236251..236253,
236353..236355,236359..236361)
/locus_tag="ECOK1_0211"
/note="putative catalytic site [active]"
/db_xref="CDD:197306"
misc_feature 236014..236016
/locus_tag="ECOK1_0211"
/note="putative metal binding site [ion binding]; other
site"
/db_xref="CDD:197306"
misc_feature order(236251..236253,236359..236361)
/locus_tag="ECOK1_0211"
/note="putative phosphate binding site [ion binding];
other site"
/db_xref="CDD:197306"
misc_feature order(236353..236355,236359..236361,236473..236475,
236536..236541)
/locus_tag="ECOK1_0211"
/note="putative catalytic site [active]"
/db_xref="CDD:197306"
misc_feature order(236359..236361,236539..236541)
/locus_tag="ECOK1_0211"
/note="putative phosphate binding site [ion binding];
other site"
/db_xref="CDD:197306"
misc_feature 236536..236538
/locus_tag="ECOK1_0211"
/note="putative metal binding site [ion binding]; other
site"
/db_xref="CDD:197306"
gene 236664..237434
/locus_tag="ECOK1_0212"
/db_xref="GeneID:12688780"
CDS 236664..237434
/locus_tag="ECOK1_0212"
/note="identified by match to protein family HMM PF01209;
match to protein family HMM PF08241; match to protein
family HMM PF08242"
/codon_start=1
/transl_table=11
/product="UbiE/COQ5 family methyltransferase"
/protein_id="YP_006099460.1"
/db_xref="GI:386597954"
/db_xref="GeneID:12688780"
/translation="MTTQSHHDHVEKQFSSQASEYLTSTVHASGRDLQRLAVRLADYP
DASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAE
SLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWL
QTVEALRDTSHVRNYASGEWLRLINEANLIVDNLITDKLPLEFSSWVARMRTPEALVD
AIRIYQQSASTEVKTYFALQNDGSFTSDIIMVEAHKAA"
misc_feature 236793..237227
/locus_tag="ECOK1_0212"
/note="Methyltransferase domain; Region: Methyltransf_31;
pfam13847"
/db_xref="CDD:206018"
misc_feature 236805..237107
/locus_tag="ECOK1_0212"
/note="S-adenosylmethionine-dependent methyltransferases
(SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
that use S-adenosyl-L-methionine (SAM or AdoMet) as a
substrate for methyltransfer, creating the product
S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
cd02440"
/db_xref="CDD:100107"
misc_feature order(236814..236834,236880..236885,236958..236966,
237012..237014)
/locus_tag="ECOK1_0212"
/note="S-adenosylmethionine binding site [chemical
binding]; other site"
/db_xref="CDD:100107"
gene complement(237481..238839)
/gene="mltD"
/locus_tag="ECOK1_0213"
/db_xref="GeneID:12688781"
CDS complement(237481..238839)
/gene="mltD"
/locus_tag="ECOK1_0213"
/EC_number="2.4.-.-"
/note="identified by similarity to SP:P0AEZ7; match to
protein family HMM PF01464; match to protein family HMM
PF01476; match to protein family HMM PF06474"
/codon_start=1
/transl_table=11
/product="membrane-bound lytic murein transglycosylase D"
/protein_id="YP_006099461.1"
/db_xref="GI:386597955"
/db_xref="GeneID:12688781"
/translation="MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQA
RWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYM
YWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNY
DARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDF
WSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVAD
MAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVAD
NTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQR
LANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNNMP
DS"
misc_feature complement(237484..238839)
/gene="mltD"
/locus_tag="ECOK1_0213"
/note="membrane-bound lytic murein transglycosylase D;
Provisional; Region: mltD; PRK10783"
/db_xref="CDD:182727"
misc_feature complement(238123..238497)
/gene="mltD"
/locus_tag="ECOK1_0213"
/note="Lytic Transglycosylase (LT) and Goose Egg White
Lysozyme (GEWL) domain. Members include the soluble and
insoluble membrane-bound LTs in bacteria, the LTs in
bacteriophage lambda, as well as, the eukaryotic
'goose-type' lysozymes (GEWL). LTs...; Region: LT_GEWL;
cd00254"
/db_xref="CDD:238157"
misc_feature complement(order(238255..238257,238312..238314,
238405..238407,238465..238467))
/gene="mltD"
/locus_tag="ECOK1_0213"
/note="N-acetyl-D-glucosamine binding site [chemical
binding]; other site"
/db_xref="CDD:238157"
misc_feature complement(238465..238467)
/gene="mltD"
/locus_tag="ECOK1_0213"
/note="catalytic residue [active]"
/db_xref="CDD:238157"
misc_feature complement(237688..237819)
/gene="mltD"
/locus_tag="ECOK1_0213"
/note="Lysine Motif is a small domain involved in binding
peptidoglycan; Region: LysM; cd00118"
/db_xref="CDD:212030"
misc_feature complement(237514..237642)
/gene="mltD"
/locus_tag="ECOK1_0213"
/note="Lysine Motif is a small domain involved in binding
peptidoglycan; Region: LysM; cd00118"
/db_xref="CDD:212030"
gene complement(238911..239666)
/gene="gloB"
/locus_tag="ECOK1_0214"
/db_xref="GeneID:12688782"
CDS complement(238911..239666)
/gene="gloB"
/locus_tag="ECOK1_0214"
/EC_number="3.1.2.6"
/note="identified by similarity to SP:P0AC84; match to
protein family HMM PF00753; match to protein family HMM
TIGR03413"
/codon_start=1
/transl_table=11
/product="hydroxyacylglutathione hydrolase"
/protein_id="YP_006099462.1"
/db_xref="GI:386597956"
/db_xref="GeneID:12688782"
/translation="MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAISANNW
QPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEF
SVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTPSQMYQSIKKLSALPDDTL
VCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLR
TEDIDLINVINEETLLQQPEERFAWLRSKKDRF"
misc_feature complement(238914..239666)
/gene="gloB"
/locus_tag="ECOK1_0214"
/note="hydroxyacylglutathione hydrolase; Provisional;
Region: PRK10241"
/db_xref="CDD:182327"
misc_feature complement(239001..239651)
/gene="gloB"
/locus_tag="ECOK1_0214"
/note="Zn-dependent hydrolases, including glyoxylases
[General function prediction only]; Region: GloB; COG0491"
/db_xref="CDD:30837"
gene 239700..240422
/locus_tag="ECOK1_0216"
/db_xref="GeneID:12688783"
CDS 239700..240422
/locus_tag="ECOK1_0216"
/note="identified by match to protein family HMM PF08241"
/codon_start=1
/transl_table=11
/product="putative methyltransferase"
/protein_id="YP_006099463.1"
/db_xref="GI:386597957"
/db_xref="GeneID:12688783"
/translation="MKPARVPQTVVAPDCWGDLPWGELYRKALERQLNPWFTKMYGFH
LLKIGNLSAEINCEACAVSHQVNVSAQGMPVQVQADPLHLPFADKSVDVCLLAHTLPW
CTDPHRLLREADRVLIDDGWLVISGFNPISLMGLRKLVPVLRKTSPYNSRMFTLMRQL
DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQ
SKNKPRIRQAVGATRQCRKPQA"
misc_feature <239859..240077
/locus_tag="ECOK1_0216"
/note="S-adenosylmethionine-dependent methyltransferases
(SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
that use S-adenosyl-L-methionine (SAM or AdoMet) as a
substrate for methyltransfer, creating the product
S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
cd02440"
/db_xref="CDD:100107"
gene complement(240419..240886)
/gene="rnhA"
/locus_tag="ECOK1_0215"
/db_xref="GeneID:12688784"
CDS complement(240419..240886)
/gene="rnhA"
/locus_tag="ECOK1_0215"
/EC_number="3.1.26.4"
/note="identified by match to protein family HMM PF00075"
/codon_start=1
/transl_table=11
/product="ribonuclease H"
/protein_id="YP_006099464.1"
/db_xref="GI:386597958"
/db_xref="GeneID:12688784"
/translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTN
NRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVD
LWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV"
misc_feature complement(240464..240877)
/gene="rnhA"
/locus_tag="ECOK1_0215"
/note="RNase HI family found mainly in prokaryotes;
Region: RNase_HI_prokaryote_like; cd09278"
/db_xref="CDD:187702"
misc_feature complement(order(240473..240475,240527..240529,
240677..240679,240743..240745,240752..240760,
240848..240859))
/gene="rnhA"
/locus_tag="ECOK1_0215"
/note="RNA/DNA hybrid binding site [nucleotide binding];
other site"
/db_xref="CDD:187702"
misc_feature complement(order(240485..240487,240677..240679,
240743..240745,240857..240859))
/gene="rnhA"
/locus_tag="ECOK1_0215"
/note="active site"
/db_xref="CDD:187702"
gene 240951..241682
/gene="dnaQ"
/locus_tag="ECOK1_0217"
/db_xref="GeneID:12688785"
CDS 240951..241682
/gene="dnaQ"
/locus_tag="ECOK1_0217"
/EC_number="2.7.7.7"
/note="identified by similarity to SP:P03007; match to
protein family HMM PF00929; match to protein family HMM
TIGR00573; match to protein family HMM TIGR01406"
/codon_start=1
/transl_table=11
/product="DNA polymerase III subunit epsilon"
/protein_id="YP_006099465.1"
/db_xref="GI:386597959"
/db_xref="GeneID:12688785"
/translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLT
GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAF
DIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRT
LHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGETTIQRIVRQASKLRVVFAT
DEELAAHEARLDLVQKKGGSCLWRA"
misc_feature 240969..241658
/gene="dnaQ"
/locus_tag="ECOK1_0217"
/note="DNA polymerase III, epsilon subunit,
Proteobacterial; Region: dnaQ_proteo; TIGR01406"
/db_xref="CDD:130473"
misc_feature 240972..241487
/gene="dnaQ"
/locus_tag="ECOK1_0217"
/note="DEDDh 3'-5' exonuclease domain of the epsilon
subunit of Escherichia coli DNA polymerase III and similar
proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131"
/db_xref="CDD:99835"
misc_feature order(240984..240995,240999..241004,241131..241136,
241143..241148,241242..241247,241251..241259,
241380..241385,241425..241427,241434..241436,
241449..241451)
/gene="dnaQ"
/locus_tag="ECOK1_0217"
/note="active site"
/db_xref="CDD:99835"
misc_feature order(240984..240995,240999..241004,241131..241136,
241143..241148,241242..241247,241251..241256,
241380..241385,241425..241427,241434..241436,
241449..241451)
/gene="dnaQ"
/locus_tag="ECOK1_0217"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:99835"
misc_feature order(240984..240986,240990..240992,241257..241259,
241434..241436,241449..241451)
/gene="dnaQ"
/locus_tag="ECOK1_0217"
/note="catalytic site [active]"
/db_xref="CDD:99835"
gene 241815..241891
/locus_tag="ECOK1_0218"
/db_xref="GeneID:12688786"
tRNA 241815..241891
/locus_tag="ECOK1_0218"
/product="tRNA-Asp"
/db_xref="GeneID:12688786"
gene 242023..242166
/locus_tag="ECOK1_0219"
/db_xref="GeneID:12688787"
CDS 242023..242166
/locus_tag="ECOK1_0219"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099466.1"
/db_xref="GI:386597960"
/db_xref="GeneID:12688787"
/translation="MSLIFNHAIESFNLNIFARYDFHFSIDLMNLYLLLFFVCSDSSG
VYN"
gene 242220..243005
/locus_tag="ECOK1_0220"
/db_xref="GeneID:12688788"
CDS 242220..243005
/locus_tag="ECOK1_0220"
/codon_start=1
/transl_table=11
/product="putative lipoprotein"
/protein_id="YP_006099467.1"
/db_xref="GI:386597961"
/db_xref="GeneID:12688788"
/translation="MNLKKVCCICVLFSLLAGCASESPIDEKKKKTQTTQISINKNVP
QQLTDKDLYGNETTLAVSEEDIQAALEGDEFRVPLNSPVILVQSGSRAPETIMQEEMR
KYYTVATFSGIPDRKKTVTCNKDKNKDESLDIVDAENMNWMQALRFVAAKGHQKAIIV
FQDTLQTGKYDSGLKSIVWTDYKNQKLTDTMSLRYLVRFTLVDVATGEWATWSPVNYE
SKVIFPQIGNKNSDSLDVAEQQISQLKQKTYAAVVKDLVNRYQ"
gene complement(243345..243824)
/locus_tag="ECOK1_0221"
/db_xref="GeneID:12688789"
CDS complement(243345..243824)
/locus_tag="ECOK1_0221"
/note="identified by similarity to GB:CAE12300.1; match to
protein family HMM PF05638; match to protein family HMM
TIGR03344"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099468.1"
/db_xref="GI:386597962"
/db_xref="GeneID:12688789"
/translation="MANPVYLTLNGELQGLISSGCSSMPSIGNKAQIAHQDQIMVTSL
SHGLSRAQNVNHQELTITKPVDKSSPLLGKAISENECLTCDFVFYRTNRFGINEPYYK
LKLANARLSNIGLTVPHTINDSPGQAEESVSFTYESINWEHSVAGTSAYSLWSERIF"
misc_feature complement(243354..243821)
/locus_tag="ECOK1_0221"
/note="Protein of unknown function (DUF796); Region:
DUF796; cl01226"
/db_xref="CDD:214110"
gene complement(243842..245200)
/locus_tag="ECOK1_0222"
/db_xref="GeneID:12688790"
CDS complement(243842..245200)
/locus_tag="ECOK1_0222"
/note="identified by match to protein family HMM PF06812"
/codon_start=1
/transl_table=11
/product="ImpA domain-containing protein"
/protein_id="YP_006099469.1"
/db_xref="GI:386597963"
/db_xref="GeneID:12688790"
/translation="MSNYALTQTIVTGSDPRALPEFSAIREEINKANHPSQPELNWKL
VESLALSIFKANGVDLHTATYYTLARTRNQGLAGFCEGAELLAAMIIHEWDKFWPQSG
PARTEMLDWFNTRTGNILRQQVSFSENDLSLLYRTERALQLICDKLQQVELKRQPRVE
NLLYFVQNTRKRFEPQPRNRTDTAAQTMVRTLVYAPEGTASATAETMPPLPDLPEMRV
GVRGVADNADKAKQGDTVKGFVAGAACTAVIASALWWWQAYPMQQQLTQVRDTTQGAA
TVWLASPVLKEYEQYLQQLLNAPPLQPLETGMQMMRTADTLWPESLQQQEASRMWSNT
LRNRAQASPQMKGWQQARQNLRDFADLMMKKETEKQGFTLSYIKTVTWQAERLLNQET
PLEYLLTQYQETRTQKQDTQALEKEINERLDGLLSRWLLLKNTGQDMATDNRTEPVHP
TH"
misc_feature complement(244208..245200)
/locus_tag="ECOK1_0222"
/note="Predicted component of the type VI protein
secretion system [Intracellular trafficking, secretion,
and vesicular transport]; Region: COG3515"
/db_xref="CDD:33318"
misc_feature complement(244895..245080)
/locus_tag="ECOK1_0222"
/note="ImpA-related N-terminal; Region: ImpA-rel_N;
pfam06812"
/db_xref="CDD:203522"
misc_feature complement(243938..244288)
/locus_tag="ECOK1_0222"
/note="ImpA domain protein; Region: DUF3702; pfam12486"
/db_xref="CDD:193049"
gene complement(245211..248678)
/locus_tag="ECOK1_0223"
/db_xref="GeneID:12688791"
CDS complement(245211..248678)
/locus_tag="ECOK1_0223"
/note="identified by similarity to GB:AAQ96724.1; match to
protein family HMM PF06744; match to protein family HMM
PF06761; match to protein family HMM TIGR03348"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099470.1"
/db_xref="GI:386597964"
/db_xref="GeneID:12688791"
/translation="MPRFKVSATWLLTLAWIFLLVWIWWQGPKWTLYEQHWLAPLANR
WLATAVWGLIALVWLTWRVMKRLQKLEKQQKQQREEEKDPLTVELHRQQQYLDHWLLR
LRRHLDNRRYLWQLPWYMVIGPAGSGKSTLLREGFPSDIVYTPESIRGVEYHPLITPR
VGNQAVIFDVDGVLTTPGGDDLLRRRLREHWLGWLMQTRARQPLNGLILTLDLPDLLT
ADKSRRETLVQNLRQQLQEIRQSLHCRLPVYVVLTRLDLLNGFAALFHSLDKKDRDAI
LGVTFTRRAHESDGWRSELGAFWQTWVQQVNLALSDLVLAQTGAAPRSAVFSFSRQMQ
GTGEIVTALLAALLDGENMDVMLRGVWLTSSLQRGQVDDIFTQSAARQYGLGNSSLAT
WPLVETTPYFTRRLFPEVLLAEPNLAGENSVWLNSSRRRLTAFSTCGAALAALMVGSW
HHYYNQNWQSGVNVLAQAKAFMDVPPPQGTDEFGNLQLPLLNPVRDATLAYGDYRDHG
FLADMGLYQGARVGPYVEQTYIQLLEQRYLPSLMNGLIRDLNIAPPESEEKLAVLRVV
RMMEDKSGRNNEAVKQYMARRWSNEFHGQRDIQAQLMVHLDYALEHTDWHAQRQSSDS
DAVSRWTPYDKPIINAQQELSKLPIYQRVYQTLRTKALSVLPADLNLRDQVGPTFDNV
FVAGNDEKLVIPQFLTRYGLQSYFVKQREGLVELTALDSWVLNLTQSVAYSEADREEI
QRHITEQYISDYTATWRAGMDNLNVRDYEAMSALTDALEQIISGDQPFQRALTALRDN
THALTLSGKLDDKAREAAINEMDYRLLSRLGHEFAPENSALEEQKDKASTLQAVYQQL
TELHRYLLAIQNSPVPGKSALKAVQLRLDQNSSDPIFATRQMAKTLPAPLNRWVGKLA
DQAWHVVMVEAVRYMEVDWRDNVVKPFNEQLADNYPFNPRATQDASLDSFERFFKPDG
ILDNFYKNNLRLFLENDLTFGDDGRVLIREDIRQQLDTAQKIRDIFFSQQNGLGAQFA
VETVSLSGNKRRSVLNLDGQLVDYSQGRNYTAHLVWPNNMREGNESKLTLIGTSGRAP
RSIAFSGPWAQFRLFGAGQLTNVTSDTFNVRFNVDGGAMVYQVHVDTEDNPFTGGLFS
LFRLPDTLY"
misc_feature complement(245214..248678)
/locus_tag="ECOK1_0223"
/note="Type VI protein secretion system component VasK
[Intracellular trafficking, secretion, and vesicular
transport]; Region: IcmF; COG3523"
/db_xref="CDD:33326"
misc_feature complement(247344..248105)
/locus_tag="ECOK1_0223"
/note="ImcF-related N-terminal domain; Region:
ImcF-related_N; pfam14331"
/db_xref="CDD:206499"
misc_feature complement(246276..247220)
/locus_tag="ECOK1_0223"
/note="Intracellular multiplication and human
macrophage-killing; Region: IcmF-related; pfam06761"
/db_xref="CDD:148393"
misc_feature complement(245637..245996)
/locus_tag="ECOK1_0223"
/note="Protein of unknown function (DUF1215); Region:
DUF1215; pfam06744"
/db_xref="CDD:148380"
gene complement(248758..250200)
/locus_tag="ECOK1_0224"
/db_xref="GeneID:12688792"
CDS complement(248758..250200)
/locus_tag="ECOK1_0224"
/note="identified by similarity to GB:AAS64092.1; match to
protein family HMM TIGR03362"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099471.1"
/db_xref="GI:386597965"
/db_xref="GeneID:12688792"
/translation="MAMDLRNPDVWLAHLLENLPEDKLSAALDDGNADWEFVDSEIVK
LGSLAHSQLDIPELQRRGLMLLASETKDFRLLAHLLRTLQHAGDILLASRMLAQYTEH
YWTCAAPQNMAHKKRFAAQVIKRFESAVQDFAGNAATIQRDALLGELAKLAQCWQAHN
ASELAKATDDLFSLFQRAFRDVAPEMTSSARSAAIAPQATTGYVPDMSPHTVAAQPPV
AATPIPQVTVENHDDKAWRDTLLKVAAILCERQPESPQGYRLRRHALWQTITSTPQAE
SDGRTPLAAFPVDMMDDYLARLNNADMALWQQVEKSLLLAPYWLDGHYLSAQTALRLG
YKQVADAIRDEVTDFLARLPALINLLFNDRTPFVSEQTKQWLASSGSVNQTVPVVQTD
EELQAAKACFDENGLEAALRYLENLPEGDPRHQFHRQFFGAQLLEEAGMVQLAQQQYR
MLFRTGLHMMLSEWEPSLLKALEQKLTAEQ"
misc_feature complement(249871..250041)
/locus_tag="ECOK1_0224"
/note="ImpA-related N-terminal; Region: ImpA-rel_N;
pfam06812"
/db_xref="CDD:203522"
misc_feature complement(248761..249516)
/locus_tag="ECOK1_0224"
/note="Predicted component of the type VI protein
secretion system [Intracellular trafficking, secretion,
and vesicular transport]; Region: COG3515"
/db_xref="CDD:33318"
misc_feature complement(248770..249516)
/locus_tag="ECOK1_0224"
/note="type VI secretion-associated protein, VC_A0119
family; Region: VI_chp_7; TIGR03362"
/db_xref="CDD:163234"
gene complement(250205..250948)
/locus_tag="ECOK1_0225"
/db_xref="GeneID:12688793"
CDS complement(250205..250948)
/locus_tag="ECOK1_0225"
/note="identified by match to protein family HMM
TIGR03360"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099472.1"
/db_xref="GI:386597966"
/db_xref="GeneID:12688793"
/translation="MSRLCVFRQTGWFIAGLMAGLPASAAPTETSSVAGVAVAVATAT
PPDATATLQAMQSCRQETAALERLDCYDRILAPEQAGFGGAALVKARYQGEAWARATE
QEKRRQGNTTELLVTQVPGERPTVVITTPAIGHVPPRPVLMFSCVDNITRMQVALMHP
LDVHDIAVTLNADSRALRSHWFVRENGTLLESSRGLSGIDEIKQLFGAKTLTVDTGTD
NAAGKLTFNIDGLARVIAPLRDACHWAGE"
misc_feature complement(250217..250789)
/locus_tag="ECOK1_0225"
/note="type VI secretion-associated protein, VC_A0118
family; Region: VI_minor_1; TIGR03360"
/db_xref="CDD:132403"
gene complement(250945..253704)
/gene="clpB"
/locus_tag="ECOK1_0226"
/db_xref="GeneID:12688794"
CDS complement(250945..253704)
/gene="clpB"
/locus_tag="ECOK1_0226"
/note="identified by match to protein family HMM PF02861;
match to protein family HMM PF07724; match to protein
family HMM PF07728; match to protein family HMM TIGR03345"
/codon_start=1
/transl_table=11
/product="ATP-dependent chaperone protein ClpB"
/protein_id="YP_006099473.1"
/db_xref="GI:386597967"
/db_xref="GeneID:12688794"
/translation="MIQIDLATLVKRLNPFAKQALEMAASECMSQQASEITVAHVLLQ
MLAIPRNDVRVIAERTGISAEDLRQALTVESYPGGRSAEGYPSFSPMLIEWLKESWLL
ASAQMQHSELRSGVLLLTLLHSPLRYIPPAAARLLTAINRDQLQQDFAAWTKESAESV
DLAGGQTPRATETGDTLLARYAKNMTADARNGRLDPVLCRNYEIDLMIDILCRRRKNN
PVVVGEAGVGKSALIEGLALRIVAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEKRF
KGLMAEVIFSPVPVILFIDEAHTLIGAGNQQGGLDISNLLKPALARGELKTIAATTWS
EYKKYFEKDAALSRRFQLVKVSEPNAAEATIILRGLSAVYEQSHGVLIDDDALQAAAT
LSERYLSGRQLPDKAIDVLDTACARVAINLSSPPKQISALTTLSHQQEAEIRQLEREL
RIGLRTDTSRMTEVLEQYDETLSALDELEVAWQQQTLVQEIIALRQQLLGVAEDDVAS
LPDADAVEDTPPEAEQDSTDAESADDAGSVQPEETAETVSPVQRLAQLTAELDALHND
QLLVSPHVDKKQIAAVIAEWTGVPLNRLSQNEMSVITDLPVWLGGTIKGQDLAIASLH
KHLLTARADLRRPGRPLGAFLLAGPSGVGKTETVLQLAELLYGGRQYLTTINMSEFQE
KHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLFYQAFDKG
EMADGEGRLIDCKNIVFFLTSNLGYQVIVEHADDPETMQEALYPVLADFFKPALLARM
EVVPYLPLSKETLATIIAGKLARLDNVLRSRFGADVIIGPEVTDEIMSRVTRAENGAR
MLESVIDGDMLPPLSLLLLQKMAANTAIARIRLSAADGAFTADVEDALPDDAVTPQTE
DETVL"
misc_feature complement(251032..253668)
/gene="clpB"
/locus_tag="ECOK1_0226"
/note="type VI secretion ATPase, ClpV1 family; Region:
VI_ClpV1; TIGR03345"
/db_xref="CDD:163222"
misc_feature complement(252646..253098)
/gene="clpB"
/locus_tag="ECOK1_0226"
/note="The AAA+ (ATPases Associated with a wide variety of
cellular Activities) superfamily represents an ancient
group of ATPases belonging to the ASCE (for additional
strand, catalytic E) division of the P-loop NTPase fold.
The ASCE division also includes ABC; Region: AAA; cd00009"
/db_xref="CDD:99707"
misc_feature complement(253015..253038)
/gene="clpB"
/locus_tag="ECOK1_0226"
/note="Walker A motif; other site"
/db_xref="CDD:99707"
misc_feature complement(order(252709..252711,252820..252822,
253012..253035))
/gene="clpB"
/locus_tag="ECOK1_0226"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:99707"
misc_feature complement(252817..252834)
/gene="clpB"
/locus_tag="ECOK1_0226"
/note="Walker B motif; other site"
/db_xref="CDD:99707"
misc_feature complement(252658..252660)
/gene="clpB"
/locus_tag="ECOK1_0226"
/note="arginine finger; other site"
/db_xref="CDD:99707"
misc_feature complement(251419..251865)
/gene="clpB"
/locus_tag="ECOK1_0226"
/note="The AAA+ (ATPases Associated with a wide variety of
cellular Activities) superfamily represents an ancient
group of ATPases belonging to the ASCE (for additional
strand, catalytic E) division of the P-loop NTPase fold.
The ASCE division also includes ABC; Region: AAA; cd00009"
/db_xref="CDD:99707"
misc_feature complement(251740..251763)
/gene="clpB"
/locus_tag="ECOK1_0226"
/note="Walker A motif; other site"
/db_xref="CDD:99707"
misc_feature complement(order(251419..251421,251545..251547,
251737..251760))
/gene="clpB"
/locus_tag="ECOK1_0226"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:99707"
misc_feature complement(251542..251559)
/gene="clpB"
/locus_tag="ECOK1_0226"
/note="Walker B motif; other site"
/db_xref="CDD:99707"
misc_feature complement(251017..251289)
/gene="clpB"
/locus_tag="ECOK1_0226"
/note="C-terminal, D2-small domain, of ClpB protein;
Region: ClpB_D2-small; smart01086"
/db_xref="CDD:198154"
gene complement(253714..254478)
/locus_tag="ECOK1_0227"
/db_xref="GeneID:12688795"
CDS complement(253714..254478)
/locus_tag="ECOK1_0227"
/note="identified by similarity to GB:AAQ96720.1; match to
protein family HMM TIGR03349"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099474.1"
/db_xref="GI:386597968"
/db_xref="GeneID:12688795"
/translation="MSDMSEASVFPVEPESGTPGRQYRLALRGNSLNPMIDAATPLLG
MVMRLSTMNSQAMPEHLFTQVVTDVQAVEQLLQEQGYEPGVIVSFRYILCTFIDEAAL
GNGWSNKNEWIKQSLLVHFHNEAWGGEKVFILLERLIREPVRYQDLLEFLYLCFSLGF
RGRYKVAIQQQDEFERIYQRLHHALHKLRGDAPFPLLHQKNNIQGGRYQLIRRLTIKH
VLCGGLVVLTVFYLFYLLRLDSQTQDILHQLNKLLR"
misc_feature complement(253717..254436)
/locus_tag="ECOK1_0227"
/note="Type VI protein secretion system component VasF
[Intracellular trafficking, secretion, and vesicular
transport]; Region: COG3455"
/db_xref="CDD:33258"
gene complement(254483..255829)
/locus_tag="ECOK1_0228"
/db_xref="GeneID:12688796"
CDS complement(254483..255829)
/locus_tag="ECOK1_0228"
/note="identified by similarity to GB:CAH22869.1; match to
protein family HMM PF05936; match to protein family HMM
TIGR03353"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099475.1"
/db_xref="GI:386597969"
/db_xref="GeneID:12688796"
/translation="MATMKNKVIWQEGLFALPQHFQQQQRHCEYLLTRRLDALGDFFW
GFTELSINTELLAQGKIMIDRAAGCMPDGTVFSIPDQDLLPEPFQPGTLSSKESHNIY
LALPVISDVINEIQGLHSAGQGTERYRLTHTRVRDFHTDEGDEQPVGLGQLIPRIVSG
ADDLSAMVTLPLCRILNKNATGALVLDNTFIPTIQAVRVSGLLGAFSGEVQGLLATRA
ADLAGRIGSPEQSGIADVAEFMMLQMLNRYQMQFTHRSQLHTLHPEAFYRDLVGLLGE
LMTFTEGNRLPCTVEPYNHRDLTATFTRTVIPELRRALNTVLVPRAQNLPLFFSEGTW
IATINDPTLLQSCKLVLAVRARMPYDQVQRQFIQQSKVAATDKIRSVVSVQVPGIPLH
TLTAAPRQLPYHEGYVYFELEKGTPAWQDVIKAGALALHISGSFPDLNLQLWAIRG"
misc_feature complement(254486..255817)
/locus_tag="ECOK1_0228"
/note="Predicted component of the type VI protein
secretion system [Intracellular trafficking, secretion,
and vesicular transport]; Region: COG3522"
/db_xref="CDD:33325"
misc_feature complement(254489..255772)
/locus_tag="ECOK1_0228"
/note="Bacterial protein of unknown function (DUF876);
Region: DUF876; pfam05936"
/db_xref="CDD:203353"
gene complement(255832..256356)
/locus_tag="ECOK1_0229"
/db_xref="GeneID:12688797"
CDS complement(255832..256356)
/locus_tag="ECOK1_0229"
/note="identified by match to protein family HMM
TIGR03352"
/codon_start=1
/transl_table=11
/product="type VI secretion lipoprotein"
/protein_id="YP_006099476.1"
/db_xref="GI:386597970"
/db_xref="GeneID:12688797"
/translation="MNGKAFLACVLMSVVLTGCETAKKISQVIRNPDIQVGKLMDQST
ELTVTLLTEPDSNLTADGEAAPVDVQLVYLSDDSKFHAADYDQVATTALPDVLGKNYI
DHQDFNLLPDTVKTLPPIKLDEKTGYIGVIAYFSDDQATEWKQIESVESIGHHYRLLV
HIRASAIEMKKEEN"
misc_feature complement(255856..256347)
/locus_tag="ECOK1_0229"
/note="Type VI secretion lipoprotein; Region: T6SS-SciN;
cl01405"
/db_xref="CDD:214115"
gene complement(256353..257633)
/locus_tag="ECOK1_0230"
/db_xref="GeneID:12688798"
CDS complement(256353..257633)
/locus_tag="ECOK1_0230"
/note="identified by similarity to GB:CAH22871.1; match to
protein family HMM TIGR03354"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099477.1"
/db_xref="GI:386597971"
/db_xref="GeneID:12688798"
/translation="MAEEKQQSRQASLTLQVMNGNELESGRAAKCLFSENGGDIGHTP
ECHWQVQDRAGSIAARACTVIRHDGAYCLRCLTPGLMINLAPASSDALIRLRQGDEIQ
LGALALKVFLHDGAAVTYDERMATPETIVMNRDSLADTLLTTEGQPAYPGMPFQHQLA
PTVAHGFSSDPLQALQTESLMVADDPIAPRVSRPVAPASDLTGANGINTPFMDLPPGN
ARHEDGDEFSAMAQYHLAVTPLLRGMECPLTLHNSQDADEFLEEAGRALQAAIKGLLS
LQQQQNSLSDKHLRPLEDNPLRLDMDYATALNVMFAEGKSPVHLAAPAAIAESLRNIR
HHEEANRAAIVEALRVMLDAFSPGNLMRRFAQYRRSHELRQKMDDAWAWQMYSNYYDE
LASSRQQGFEMLFNEVYAQVYDRVLRETQREPEA"
misc_feature complement(256380..257597)
/locus_tag="ECOK1_0230"
/note="type VI secretion system FHA domain protein;
Region: VI_FHA; TIGR03354"
/db_xref="CDD:213804"
misc_feature complement(257322..257516)
/locus_tag="ECOK1_0230"
/note="FHA domain; Region: FHA; pfam00498"
/db_xref="CDD:201267"
gene complement(257650..258699)
/locus_tag="ECOK1_0231"
/db_xref="GeneID:12688799"
CDS complement(257650..258699)
/locus_tag="ECOK1_0231"
/note="identified by similarity to GB:AAS64100.1; match to
protein family HMM PF06996; match to protein family HMM
TIGR03347"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099478.1"
/db_xref="GI:386597972"
/db_xref="GeneID:12688799"
/translation="MAGENGPARPDIATKPPLPADVRNCNFYVLMEALYRRHGAPGQD
ISLRTEPAREIVRFSSDASISFPGTDLSALSRSQNGQYVLQTRFLGFSGSQSPLPGYY
LDQMAQESAQNEDGLKEFLDLFSHRWTQFAYHAWRKYRYYICFRSGGTDTFSQRMYAL
VGLGNQSVRDRLAINHSKMLAYAGILATPGRAPEVICNLVSHCFDLPDVTIERWQLRK
VAIDPAHQNRLGVRNPKGKTAGHIPGRSILGVNFTLGARVPDRSGKFLLQIGGLSRER
YLSFLPDGENHLPLTMFLSFILRDQFAWDLRLCLAPQQAKGMRLSDPASSRLGRTSFI
GQPKVPPAITIRIRE"
misc_feature complement(257695..258639)
/locus_tag="ECOK1_0231"
/note="type VI secretion protein, VC_A0111 family; Region:
VI_chp_1; TIGR03347"
/db_xref="CDD:163224"
gene complement(258663..260504)
/locus_tag="ECOK1_0232"
/db_xref="GeneID:12688800"
CDS complement(258663..260504)
/locus_tag="ECOK1_0232"
/note="identified by match to protein family HMM PF05947;
match to protein family HMM TIGR03359"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099479.1"
/db_xref="GI:386597973"
/db_xref="GeneID:12688800"
/translation="MAFEERYYREELDYLRQLGKLLAQEKPHLAHFLAEKEGDPDVER
LMEAFAFMSGSLRQKLEDEFPEFTHGLIRMLWANYLRPVPAMTVIAYEPKTDQLKVPV
QVCRNELIRSRSEKSSLTAQKVLPDNHDKIVSSVACHFTLARDIWLQPLRILDTRNAS
SLKEGIIDISFTADNNVSPAMLDLNKITFWLGNEDDYTRHQLYLWFCECLMDAELIAG
EYRLPLPDLWLEAAGFDNRDALLPWPKNVHSGYRVLQEYFCYPEAFFFFHLRDVAPLP
DDFPINAFTLRLHFNRPLPADIKLRQDSLRLHCTPAINLFTHYAEPVRPDGRMAEYPL
RASHKHPDAYDIFQVSTVTSKVKVSGTEISPGSQARVWPEFESFQHQMEYSRQREVVY
WHHRTKTSLLHHGLEHSIAFVHADGSIPGSSRFNDDVITTSLICTNRMIPARLHTGDI
CVAVNKNPAVASFRNVTRPTLPLWPVTDGDMHWSLISAMNLNYLSLLDRETLIQILRT
FDLPGAHHPQRARLSRQKLDAIEKLETKPVDRLFKGVPVRGLATTLWIRPDPFICEGE
IYLLGTVLSHFFALYASINSYHCLKIINTESQESWEWQEKMGQHALI"
misc_feature complement(258666..260450)
/locus_tag="ECOK1_0232"
/note="Type VI protein secretion system component VasA
[Intracellular trafficking, secretion, and vesicular
transport]; Region: COG3519"
/db_xref="CDD:33322"
misc_feature complement(258666..260450)
/locus_tag="ECOK1_0232"
/note="Bacterial protein of unknown function (DUF879);
Region: DUF879; pfam05947"
/db_xref="CDD:203356"
gene complement(260510..260935)
/locus_tag="ECOK1_0233"
/db_xref="GeneID:12688801"
CDS complement(260510..260935)
/locus_tag="ECOK1_0233"
/note="identified by similarity to GB:CAH22874.1; match to
protein family HMM PF04965; match to protein family HMM
TIGR03357"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099480.1"
/db_xref="GI:386597974"
/db_xref="GeneID:12688801"
/translation="MLRRDSGPTGSLFERIREAANPPSYQNPKEALIRSIRRNLRQVL
NTRSGSCYGSPELGITDLNDESLASSDFRREIRKSISQCILHYEPRITDVVVTAAAPD
EYAPVELCFHIVATVDVSETRGVFEFDILLDNHQRYCVE"
misc_feature complement(260516..260911)
/locus_tag="ECOK1_0233"
/note="type VI secretion system lysozyme-like protein;
Region: VI_zyme; TIGR03357"
/db_xref="CDD:163231"
gene complement(260940..262424)
/locus_tag="ECOK1_0234"
/db_xref="GeneID:12688802"
CDS complement(260940..262424)
/locus_tag="ECOK1_0234"
/note="identified by similarity to GB:CAC93174.1; match to
protein family HMM PF05943; match to protein family HMM
TIGR03355"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099481.1"
/db_xref="GI:386597975"
/db_xref="GeneID:12688802"
/translation="MSVKEEIAPVSASQTAAPPSLLDEIMAQTRVQPKSESYDITRQG
VSAFIAAMLQGDSSAEPINILAVDAMIADIDARTSRQMDAIIHAPEFQELESLLRSLK
LLVERADTRENIKVHFLNVTQEELLDDFEFAPEITQSAYYKHVYSSGYGQFGGEPVAA
VIGNFAFKNTTPDMKLLKYISQVSAMAHSPFLSSVSSEFFGLDSWTELPGIKEPGAIF
EGPAYSRWRALRESEDSRYLGLTAPRFLLRHPYSPDENPVKTFRYHEDVSQSHESYLW
GNTSFLLAANLAESFAKYRWCPNIIGPSSGGAVKDLPVHLYESMGQMQAKIPTEVLIT
DRREYELAEEGFITLTMRKGSDNACFFSANSVQKPKTFPKTPEGKAAETNYKLGTQLP
YLFVISRLAHYIKVIQREQLGSWKERSDLERELNTWIRQYVADQENPPAEVRSHRPLR
QAKIEVLDVDGEPGWYQVAISVRPHFKYMGASFDLSLVGRLDKE"
misc_feature complement(260949..262367)
/locus_tag="ECOK1_0234"
/note="Predicted component of the type VI protein
secretion system [Intracellular trafficking, secretion,
and vesicular transport]; Region: COG3517; cl05484"
/db_xref="CDD:164076"
misc_feature complement(260949..262226)
/locus_tag="ECOK1_0234"
/note="Protein of unknown function (DUF877); Region:
DUF877; pfam05943"
/db_xref="CDD:191407"
gene complement(262447..262950)
/locus_tag="ECOK1_0235"
/db_xref="GeneID:12688803"
CDS complement(262447..262950)
/locus_tag="ECOK1_0235"
/note="identified by similarity to GB:CAE12667.1; match to
protein family HMM PF05591; match to protein family HMM
TIGR03358"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099482.1"
/db_xref="GI:386597976"
/db_xref="GeneID:12688803"
/translation="MSKMNNNGGSVAPKERISVRYTPKVDGVAADIELPLNLLITGNL
KGKPDNTPLDERTAIAINRYNLNAVISEADIEREFVVPAELSDAPNEQMYVNLKVKSM
DDLSPDHIASQVPEIKRLLELREALVALKSPLGNIPAFRAQLQALLENEDTREQLIQE
LGIAVQK"
misc_feature complement(262459..262926)
/locus_tag="ECOK1_0235"
/note="Protein of unknown function (DUF770); Region:
DUF770; pfam05591"
/db_xref="CDD:203282"
gene 263656..264174
/locus_tag="ECOK1_0236"
/db_xref="GeneID:12688804"
CDS 263656..264174
/locus_tag="ECOK1_0236"
/note="identified by similarity to GB:AAQ96710.1; match to
protein family HMM PF05638; match to protein family HMM
TIGR03344"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099483.1"
/db_xref="GI:386597977"
/db_xref="GeneID:12688804"
/translation="MPTPCYISITGQTQGNITAGAFTADSVGNIYVQGHEDEMLVQEF
LHNVTVPTDPQSGQPSGQRAHKPFIFTVALNKAVPLLYNALASGEMLPKVELHWWRTS
VEGKQEHYFTTRLTDATIVDMNLHMPHCQDPAQREFTQLLAVSLAYRKVEWEHIKSGT
SGADDWRAPLEA"
misc_feature 263659..264162
/locus_tag="ECOK1_0236"
/note="Protein of unknown function (DUF796); Region:
DUF796; cl01226"
/db_xref="CDD:214110"
gene 264395..266377
/locus_tag="ECOK1_0237"
/db_xref="GeneID:12688805"
CDS 264395..266377
/locus_tag="ECOK1_0237"
/note="identified by match to protein family HMM PF04524;
match to protein family HMM PF06715; match to protein
family HMM TIGR01646; match to protein family HMM
TIGR03361"
/codon_start=1
/transl_table=11
/product="ImpA family type VI secretion-associated
protein"
/protein_id="YP_006099484.1"
/db_xref="GI:386597978"
/db_xref="GeneID:12688805"
/translation="MSLKGLRFTLEVDGQEPDTFAVVNFRLIQNQSYPFVMSVDVASD
SFMQTAEMLLEKNATLTIWQGVIPLRYVTGVVAGFGMQENNGWQMRYHLRIEPPLWRC
GLRRNFRIFQQQDIRTISATLLNENGVTEWTPLFYEDHPAREFCVQYGESDLAFLARL
WAEEGIFFFERFAADSPEQKLTLCDDVAGLSQAGELPFNPDTSAGAETECVSMFRYEA
HVRPSSVQSQDYTFKVPDWPGMYEQQGESLNGQLEQYEIFDYPGRYKDEQHGKDFTLY
RMESLRSDAEKATGQSNSPKLWPGTWFTLTGHPQKMLNREWQVVQSILSGDQPQALHG
SQGRGTTLGNQLEVIPADRTWRPRLQSKPKVDGPQSAIVTGPAGEEIFCDEHGRVRVK
FHWDRYNPATEASSCWVRVSQAWAGPGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRT
YHEDNRSPGSLPGTKTQMTIRSKTYKGSGFNELRFEDATGGEQVYIHAQKNMDTEVLN
NRTTDVKADHTETIGNDQKITVGLGQTVNVGSKKEGGHDQKVTVANDQHLTIKNDRHK
VVNNNQTSKVTGTDTEEVVKKQSIKIGDNYELKVEHGTNIISGDSIELICGQGESGTC
SIKLEKTGKIIIRGTEFLFEATGPVDIKGKDIHLNG"
misc_feature 264416..265951
/locus_tag="ECOK1_0237"
/note="type VI secretion system Vgr family protein;
Region: VI_Rhs_Vgr; TIGR03361"
/db_xref="CDD:200267"
misc_feature 264494..265384
/locus_tag="ECOK1_0237"
/note="Phage late control gene D protein (GPD); Region:
Phage_GPD; pfam05954"
/db_xref="CDD:203357"
misc_feature 265493..265777
/locus_tag="ECOK1_0237"
/note="Phage-related baseplate assembly protein; Region:
Phage_base_V; pfam04717"
/db_xref="CDD:203075"
misc_feature 265808..>265876
/locus_tag="ECOK1_0237"
/note="Putative type VI secretion system Rhs element Vgr;
Region: T6SS_Vgr; pfam13296"
/db_xref="CDD:205476"
misc_feature 265895..265963
/locus_tag="ECOK1_0237"
/note="Gp5 C-terminal repeat (3 copies); Region: Gp5_C;
pfam06715"
/db_xref="CDD:191591"
gene 266484..267530
/locus_tag="ECOK1_0238"
/db_xref="GeneID:12688806"
CDS 266484..267530
/locus_tag="ECOK1_0238"
/note="identified by similarity to GB:AAL44453.1"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099485.1"
/db_xref="GI:386597979"
/db_xref="GeneID:12688806"
/translation="MIEMKNNTPFPLLSFEKYGRYGLLFDVIAIKMSLRIKNGFYADL
AEFQKELSMSDEYYGESETSSLKSETDLVLCKRNTDIHVTGSAHAPSGDKSQWKACVR
VNSFSKELSLSGVRYLQYERNRWQMSLPDKIINVPLRYELAYGGIWQPDGMEKLVFSA
NPVGCGYYPDISQLNTSCQYKLPQITSSALSENATIFNGESDFFQGVGPVSRWWKSRL
QYAGTYNEVWREKRYPYLPDDFDERFYNSAHPDMIYTGFLSGDENISLEGFFKFEQVV
KTKLPGIRPVLILKTKHNTSHMFLPVADTMVIDLSRQEIYLTWRLTIPDFFGMKEGVL
SCIIPECIGKKYYG"
misc_feature 266538..267443
/locus_tag="ECOK1_0238"
/note="Uncharacterized protein conserved in bacteria
(DUF2169); Region: DUF2169; pfam09937"
/db_xref="CDD:204347"
gene 267523..268962
/locus_tag="ECOK1_0239"
/db_xref="GeneID:12688807"
CDS 267523..268962
/locus_tag="ECOK1_0239"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099486.1"
/db_xref="GI:386597980"
/db_xref="GeneID:12688807"
/translation="MGNYHIGDGECRFRVVCSSPDVCEVGGYKVPFDSYQTLDSERQY
SSTVWARGCRALNVGSVIAGTQSNAGKGVISGTSQGTGDCVILTGSPTVTIEGKPVAY
HGSVVGINNHNCLGKLYTKIKSPMISVIDRTFNYERTAEVIHDLLLLKDLLSVGNIFD
GDISPEVKNDLFQIKDPDQSWGEFFSIKNIRESLRNGIEGDKSQIREWFGENTLTQMG
NGAITTLHGVADLALVTFDALLDTATATVACPIGEDGLCEQANINLNEKEQALFNISN
SLINGQAWDALKKMIMDTNNGDQIALEHFASFLWGFMIPAKIPEENISGKVFVEPVVL
EGGAGGNWTVFDEVLDSNVIKQLTLTGCGAACGEMLLRDRYIFVTQNVIGTELTSMTS
LANKLNKFDVGWEGNAVSESSLYALSNTGSWGAMMWDSGSKVGHWVLVKGVDDAGNVI
IYDPYQGSRYLMTEQEFKEVWNGHSVYKP"
misc_feature 267559..267873
/locus_tag="ECOK1_0239"
/note="Domain of unknown function (DUF4150); Region:
DUF4150; pfam13665"
/db_xref="CDD:205842"
misc_feature 268588..268953
/locus_tag="ECOK1_0239"
/note="Peptidase family C39 mostly contains
bacteriocin-processing endopeptidases from bacteria. The
cysteine peptidases in family C39 cleave the
'double-glycine' leader peptides from the precursors of
various bacteriocins (mostly non-lantibiotic). The
cleavage...; Region: Peptidase_C39_like; cd02259"
/db_xref="CDD:30269"
misc_feature order(268588..268590,268606..268608,268828..268830,
268879..268881)
/locus_tag="ECOK1_0239"
/note="putative active site [active]"
/db_xref="CDD:30269"
misc_feature 268600..268887
/locus_tag="ECOK1_0239"
/note="Peptidase_C39 like family; Region: Peptidase_C39_2;
pfam13529"
/db_xref="CDD:205707"
gene 269485..270249
/locus_tag="ECOK1_0240"
/note="ISEc1, transposase, degenerate; this region
contains one or more premature stops and/or frameshifts"
/pseudo
/db_xref="GeneID:12688808"
gene 271075..271563
/locus_tag="ECOK1_0241"
/db_xref="GeneID:12688809"
CDS 271075..271563
/locus_tag="ECOK1_0241"
/note="identified by similarity to GB:AAY36505.1; match to
protein family HMM TIGR03765"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099487.1"
/db_xref="GI:386597981"
/db_xref="GeneID:12688809"
/translation="MLKMSLYVIILLFSLQFSAAITGKESEVVSPLLMDVNPSLTMEN
ISELSTSSEPSQQGVFPVICTRLHPGSVMKRQLLTGWGPVFIIGDDPFSLRWMSEHLE
ILKSLNALGLVVNVESVERMEVLQQRADGLLLLPVICDNFVQALQLNAYPVLITEMEI
SQ"
misc_feature 271135..271557
/locus_tag="ECOK1_0241"
/note="Protein of unknown function (DUF2859); Region:
DUF2859; pfam11072"
/db_xref="CDD:151517"
gene complement(271834..272604)
/locus_tag="ECOK1_0242"
/db_xref="GeneID:12688810"
CDS complement(271834..272604)
/locus_tag="ECOK1_0242"
/note="identified by match to protein family HMM PF00795"
/codon_start=1
/transl_table=11
/product="hydrolase"
/protein_id="YP_006099488.1"
/db_xref="GI:386597982"
/db_xref="GeneID:12688810"
/translation="MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMF
TSGFAMEAAASSLAQDDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTV
HFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAL
YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIA
TADAHQATRIDAELSMMALREYREKFPAWRDADEFRLW"
misc_feature complement(271837..272604)
/locus_tag="ECOK1_0242"
/note="C-N hydrolase family amidase; Provisional; Region:
PRK10438"
/db_xref="CDD:182461"
misc_feature complement(271846..272595)
/locus_tag="ECOK1_0242"
/note="Xanthomonas campestris XC1258 and related proteins,
members of the nitrilase superfamily (putative class 13
nitrilases); Region: Xc-1258_like; cd07575"
/db_xref="CDD:143599"
misc_feature complement(order(272110..272115,272170..272175,
272179..272184,272257..272259,272272..272274,
272284..272286,272461..272463,272479..272481))
/locus_tag="ECOK1_0242"
/note="putative active site [active]"
/db_xref="CDD:143599"
misc_feature complement(order(272182..272184,272284..272286,
272479..272481))
/locus_tag="ECOK1_0242"
/note="catalytic triad [active]"
/db_xref="CDD:143599"
misc_feature complement(order(271846..271863,271867..271878,
271915..271917,271921..271926,271930..271932,
271942..271968,271972..271974,272056..272061,
272065..272073,272077..272082,272089..272094,
272152..272154,272158..272172,272179..272181,
272266..272268,272278..272283))
/locus_tag="ECOK1_0242"
/note="multimer interface [polypeptide binding]; other
site"
/db_xref="CDD:143599"
misc_feature complement(order(271846..271863,271867..271878,
271960..271968,272056..272061,272065..272073,
272077..272082,272089..272094,272152..272154,
272158..272172,272179..272181,272266..272268,
272278..272283))
/locus_tag="ECOK1_0242"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:143599"
gene 272758..273231
/locus_tag="ECOK1_0243"
/db_xref="GeneID:12688811"
CDS 272758..273231
/locus_tag="ECOK1_0243"
/note="identified by similarity to SP:P0AD59; similarity
to SP:P45502; match to protein family HMM PF08816"
/codon_start=1
/transl_table=11
/product="inhibitor of vertebrate lysozyme"
/protein_id="YP_006099489.1"
/db_xref="GI:386597983"
/db_xref="GeneID:12688811"
/translation="MGRISPGGMMFKAITTVAALVIATSAMAQDDLTISSLAKGETTK
AAFNQMVQGHKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEK
SNQMTGLFSTIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK"
misc_feature 272770..273228
/locus_tag="ECOK1_0243"
/note="C-lysozyme inhibitor; Provisional; Region:
PRK09993"
/db_xref="CDD:182187"
gene complement(273274..275718)
/gene="fadE"
/locus_tag="ECOK1_0244"
/db_xref="GeneID:12688812"
CDS complement(273274..275718)
/gene="fadE"
/locus_tag="ECOK1_0244"
/EC_number="1.3.99.-"
/note="identified by similarity to SP:Q8ZRJ7; match to
protein family HMM PF00441; match to protein family HMM
PF09317"
/codon_start=1
/transl_table=11
/product="acyl-coenzyme A dehydrogenase"
/protein_id="YP_006099490.1"
/db_xref="GI:386597984"
/db_xref="GeneID:12688812"
/translation="MMILSILATVVLLSALFYHRVSLFISSLILLAWTAALGVAGLWS
AWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
FQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
DEQKNHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVMGMRLTWN
KRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVP
FQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
TGAYAYIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
VKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMI
FGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSST
PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAV
LKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRH
YLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQ
RICKELGKNLPFTRLDELAHNALAKGLIDKDEAAILVKAEESRLRSINVDDFDPEELA
TKPVKLPEKVRKVEAA"
misc_feature complement(273277..275595)
/gene="fadE"
/locus_tag="ECOK1_0244"
/note="acyl-CoA dehydrogenase; Reviewed; Region: fadE;
PRK09463"
/db_xref="CDD:181878"
misc_feature complement(274219..275265)
/gene="fadE"
/locus_tag="ECOK1_0244"
/note="Acyl-CoA dehydrogenase; Region: ACAD; cl09933"
/db_xref="CDD:209100"
misc_feature complement(order(274222..274224,274228..274236,
274876..274878,274882..274884,274999..275001,
275005..275007,275098..275100))
/gene="fadE"
/locus_tag="ECOK1_0244"
/note="active site"
/db_xref="CDD:173838"
misc_feature complement(273343..274179)
/gene="fadE"
/locus_tag="ECOK1_0244"
/note="Domain of unknown function (DUF1974); Region:
DUF1974; pfam09317"
/db_xref="CDD:150096"
gene 275958..276536
/gene="gmhA"
/locus_tag="ECOK1_0245"
/db_xref="GeneID:12688813"
CDS 275958..276536
/gene="gmhA"
/locus_tag="ECOK1_0245"
/EC_number="5.3.1.-"
/note="identified by match to protein family HMM
TIGR00441"
/codon_start=1
/transl_table=11
/product="phosphoheptose isomerase"
/protein_id="YP_006099491.1"
/db_xref="GI:386597985"
/db_xref="GeneID:12688813"
/translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFS
RYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
misc_feature 275985..276521
/gene="gmhA"
/locus_tag="ECOK1_0245"
/note="Phosphoheptose isomerase is a member of the SIS
(Sugar ISomerase) superfamily. Phosphoheptose isomerase
catalyzes the isomerization of sedoheptulose 7-phosphate
into D-glycero-D-mannoheptose 7-phosphate. This is the
first step of the biosynthesis of...; Region: SIS_GmhA;
cd05006"
/db_xref="CDD:240139"
misc_feature order(275994..275996,276006..276008,276048..276050,
276057..276059,276117..276119,276135..276140,
276471..276476,276486..276488,276495..276497,
276507..276509,276519..276521)
/gene="gmhA"
/locus_tag="ECOK1_0245"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:240139"
misc_feature order(276111..276119,276312..276320,276327..276329,
276456..276458,276471..276473)
/gene="gmhA"
/locus_tag="ECOK1_0245"
/note="active site"
/db_xref="CDD:240139"
gene 276741..277508
/locus_tag="ECOK1_0247"
/db_xref="GeneID:12688814"
CDS 276741..277508
/locus_tag="ECOK1_0247"
/note="identified by match to protein family HMM PF00310"
/codon_start=1
/transl_table=11
/product="putative glutamine amidotransferase, class-II"
/protein_id="YP_006099492.1"
/db_xref="GI:386597986"
/db_xref="GeneID:12688814"
/translation="MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
GCRTFKDPQPSFNSPIAKLVQDYPIKSCSVLAHIRQANRGEVALENTHPFTRELWGRN
WTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIA
SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTT
PNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGECVV"
misc_feature 276741..277505
/locus_tag="ECOK1_0247"
/note="Predicted glutamine amidotransferase [General
function prediction only]; Region: COG0121"
/db_xref="CDD:30470"
misc_feature 276741..277493
/locus_tag="ECOK1_0247"
/note="Glutamine amidotransferases class-II
(Gn-AT)_YafJ-type. YafJ is a glutamine
amidotransferase-like protein of unknown function found in
prokaryotes, eukaryotes and archaea. YafJ has a conserved
structural fold similar to those of other class II...;
Region: YafJ; cd01908"
/db_xref="CDD:48481"
misc_feature order(276744..276746,276975..276977,277062..277070,
277125..277127)
/locus_tag="ECOK1_0247"
/note="putative active site [active]"
/db_xref="CDD:48481"
misc_feature order(276879..276881,276888..276893,277026..277028,
277098..277103,277164..277166)
/locus_tag="ECOK1_0247"
/note="putative dimer interface [polypeptide binding];
other site"
/db_xref="CDD:48481"
gene complement(277479..278219)
/locus_tag="ECOK1_0246"
/db_xref="GeneID:12688815"
CDS complement(277479..278219)
/locus_tag="ECOK1_0246"
/note="identified by match to protein family HMM PF06104"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099493.1"
/db_xref="GI:386597987"
/db_xref="GeneID:12688815"
/translation="MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPV
YIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQ
LKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVN
GRYVVSKPLSHEVVQPQLASNYTLPEAK"
misc_feature complement(277482..278219)
/locus_tag="ECOK1_0246"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG3034"
/db_xref="CDD:225577"
misc_feature complement(277743..278093)
/locus_tag="ECOK1_0246"
/note="L,D-transpeptidase catalytic domain; Region: YkuD;
pfam03734"
/db_xref="CDD:217702"
gene complement(278476..278616)
/locus_tag="ECOK1_0248"
/db_xref="GeneID:12688816"
CDS complement(278476..278616)
/locus_tag="ECOK1_0248"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099494.1"
/db_xref="GI:386597988"
/db_xref="GeneID:12688816"
/translation="MVALASKGSKTHNENTPGCRNLPCKNEDMKDINQLNEGENFKRP
EE"
gene 278543..279280
/locus_tag="ECOK1_0249"
/db_xref="GeneID:12688817"
CDS 278543..279280
/locus_tag="ECOK1_0249"
/note="identified by match to protein family HMM PF00877"
/codon_start=1
/transl_table=11
/product="NlpC/P60 family protein"
/protein_id="YP_006099495.1"
/db_xref="GI:386597989"
/db_xref="GeneID:12688817"
/translation="MHGRFLHPGVFSLCVLLPLLASATTSHISFSYAARQRMQNRARL
LKQYQTHLKKQASYIVEGNAKSRRALRQHNREQIKQHPEWFPAPLKASDRRWQALVEN
NHFLSSDHLHNITEVAIHRLEQQLGKPYIWGGTRPDKGFDCSGLVFYAYNKILEAKLP
RTANEMYHYRRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDGQFIESPRTGETI
RVSRLAEPFWQDHFLGARRILTEETIL"
misc_feature <278831..279250
/locus_tag="ECOK1_0249"
/note="Cell wall-associated hydrolases
(invasion-associated proteins) [Cell envelope biogenesis,
outer membrane]; Region: Spr; COG0791"
/db_xref="CDD:31134"
misc_feature 278921..279253
/locus_tag="ECOK1_0249"
/note="NlpC/P60 family; Region: NLPC_P60; pfam00877"
/db_xref="CDD:189752"
gene 279456..279953
/locus_tag="ECOK1_0250"
/db_xref="GeneID:12688818"
CDS 279456..279953
/locus_tag="ECOK1_0250"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099496.1"
/db_xref="GI:386597990"
/db_xref="GeneID:12688818"
/translation="MSEYRRYYIKGGTWFFTVNLQNRRNQLLTTQFQTLRNVIIKVKR
DRPFEINAWVVLPEHMHCIWTLPEGDDDFSSRWREIKKQFTHACGLKNIWQPRFWEHA
IRNTKDYRHHVDYIYINPVKHGWVKQVSDWPFSTFHRDVAKGLYPIDWAGDVTDFSAG
ERIIL"
misc_feature 279456..279860
/locus_tag="ECOK1_0250"
/note="Transposase and inactivated derivatives [DNA
replication, recombination, and repair]; Region: COG1943"
/db_xref="CDD:32126"
gene complement(280036..280194)
/locus_tag="ECOK1_0251"
/db_xref="GeneID:12688819"
CDS complement(280036..280194)
/locus_tag="ECOK1_0251"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099497.1"
/db_xref="GI:386597991"
/db_xref="GeneID:12688819"
/translation="MIRRVAAHLAPVHNRRMRRERLIRPTGECGFVGMIRRICVASGT
GAQPPDAA"
gene complement(280273..282012)
/gene="fhiA"
/locus_tag="ECOK1_0252"
/db_xref="GeneID:12688820"
CDS complement(280273..282012)
/gene="fhiA"
/locus_tag="ECOK1_0252"
/note="identified by match to protein family HMM PF00771"
/codon_start=1
/transl_table=11
/product="protein FhiA"
/protein_id="YP_006099498.1"
/db_xref="GI:386597992"
/db_xref="GeneID:12688820"
/translation="MLSRSDLLTLLTINFIVVTKGAERISEVSARFTLDAMPGKQMAI
DADLNAGLINQTQAQTRRKDVASEADFYGAMDGASKFVRGDAIAGMMILAINLIGGVC
IGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDVRN
QLLASPSVLYTATGIMFVLAVVPGMPHFPFLMFSALLGFTGWRMSKRPQAAEAEEKSL
ETLTRTMTETSEQQVSWETIPLIEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVIS
DGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMALPSSETYGEIDGVL
GNDPAYGMPVTWIQPAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFNYDDITQ
LHNRLSSMAPRLAEDLSAALNYSQLLKVYRTLLTEGVSLRDIVTIATVLVASSAVTKD
HILLAADVRLVLRRSITHPFVRKQELTVYTLNNELENLLTNVVNQAQQAGKVMLDSVP
VDPNMLNQFQITMPQVKEQMKAAGKDPVLLVPPQLRPLLARYARLFAPGLHVLSYNEV
LDELELKIMGALM"
misc_feature complement(280282..281985)
/gene="fhiA"
/locus_tag="ECOK1_0252"
/note="flagellar biosynthesis protein FlhA; Validated;
Region: flhA; PRK06012"
/db_xref="CDD:180350"
misc_feature complement(280297..281985)
/gene="fhiA"
/locus_tag="ECOK1_0252"
/note="FHIPEP family; Region: FHIPEP; pfam00771"
/db_xref="CDD:201434"
gene 281972..282742
/locus_tag="ECOK1_0253"
/db_xref="GeneID:12688821"
CDS 281972..282742
/locus_tag="ECOK1_0253"
/note="identified by similarity to GB:AAN78859.1; match to
protein family HMM PF00691"
/codon_start=1
/transl_table=11
/product="putative chemotaxis protein"
/protein_id="YP_006099499.1"
/db_xref="GI:386597993"
/db_xref="GeneID:12688821"
/translation="MIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSHLPKPA
TVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQG
LRVLIKDDQNRNMFERGSAKIMPFFKTLLVELAPVLDSLDNKIIITGHTDAMAYKNNI
YNNWNLSGDRALSARRVLEEAGMPENKVMQVSAMADQMLLDAKNPQSAGNRRIEIMVL
TKSASDTLYQYFGQHGDKVVQPLVQKLDKQQVLSQRAR"
misc_feature 281975..282718
/locus_tag="ECOK1_0253"
/note="hypothetical protein; Validated; Region: PRK06778"
/db_xref="CDD:180691"
misc_feature 282317..282622
/locus_tag="ECOK1_0253"
/note="Peptidoglycan binding domains similar to the
C-terminal domain of outer-membrane protein OmpA; Region:
OmpA_C-like; cd07185"
/db_xref="CDD:143586"
misc_feature order(282323..282328,282422..282427,282434..282436,
282455..282460,282467..282469,282602..282604)
/locus_tag="ECOK1_0253"
/note="ligand binding site [chemical binding]; other site"
/db_xref="CDD:143586"
gene 282813..283868
/gene="dinB"
/locus_tag="ECOK1_0254"
/db_xref="GeneID:12688822"
CDS 282813..283868
/gene="dinB"
/locus_tag="ECOK1_0254"
/EC_number="2.7.7.7"
/note="identified by similarity to SP:Q47155; match to
protein family HMM PF00817"
/codon_start=1
/transl_table=11
/product="DNA polymerase IV"
/protein_id="YP_006099500.1"
/db_xref="GI:386597994"
/db_xref="GeneID:12688822"
/translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
DEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNG
QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVTLLKRFGKF
GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAK
VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKSDLIATARKTWDERRGGRGVRLVGL
HVTLLDPQMERQLVLGL"
misc_feature 282825..283778
/gene="dinB"
/locus_tag="ECOK1_0254"
/note="DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa;
cd03586"
/db_xref="CDD:176459"
misc_feature order(282834..282839,282843..282851,282936..282941,
282948..282950,282957..282959,283119..283121,
283281..283283)
/gene="dinB"
/locus_tag="ECOK1_0254"
/note="active site"
/db_xref="CDD:176459"
misc_feature 282837..283865
/gene="dinB"
/locus_tag="ECOK1_0254"
/note="DNA polymerase IV; Validated; Region: PRK02406"
/db_xref="CDD:179421"
misc_feature order(282909..282911,282984..282986,283113..283115,
283119..283124,283260..283262,283356..283376,
283461..283466,283533..283556,283629..283631,
283704..283715)
/gene="dinB"
/locus_tag="ECOK1_0254"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:176459"
gene 283920..284213
/locus_tag="ECOK1_0255"
/db_xref="GeneID:12688823"
CDS 283920..284213
/locus_tag="ECOK1_0255"
/note="identified by match to protein family HMM PF02604;
match to protein family HMM TIGR01552"
/codon_start=1
/transl_table=11
/product="prevent-host-death family protein"
/protein_id="YP_006099501.1"
/db_xref="GI:386597995"
/db_xref="GeneID:12688823"
/translation="MHRILAEKSVNITELRKNPAKYFIDQPVAVLSNNRPAGYLLSAS
AFEALMDMLAEQEEKKPIKARFRPSAARLEEITRRAEQYLNDMTDDDFNDFKE"
misc_feature 283920..284210
/locus_tag="ECOK1_0255"
/note="putative antitoxin of the YafO-YafN toxin-antitoxin
system; Provisional; Region: PRK09778"
/db_xref="CDD:170091"
gene 284216..284614
/locus_tag="ECOK1_0256"
/db_xref="GeneID:12688824"
CDS 284216..284614
/locus_tag="ECOK1_0256"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099502.1"
/db_xref="GI:386597996"
/db_xref="GeneID:12688824"
/translation="MRVFKTKLIRLQLTAEELEALTADFISYKRDGVLPDIFGRDALY
DDSFTWPLIKFERVAHIHLANVNNPFPPQLRQFSRTNDAAHLVYCQGAFDEQAWLLIA
ILKPEPHKLARDNNQMHKIGKMAEAFRMRF"
misc_feature 284216..284611
/locus_tag="ECOK1_0256"
/note="putative toxin YafO; Provisional; Region: PRK09885"
/db_xref="CDD:182132"
gene 284624..285076
/locus_tag="ECOK1_0257"
/db_xref="GeneID:12688825"
CDS 284624..285076
/locus_tag="ECOK1_0257"
/note="identified by match to protein family HMM PF00583"
/codon_start=1
/transl_table=11
/product="GNAT family acetyltransferase"
/protein_id="YP_006099503.1"
/db_xref="GI:386597997"
/db_xref="GeneID:12688825"
/translation="MNNIQIRNYQPGDFQQLCAIFLRAVTMTASQHYSPQQIAAWAQI
DESRWKEKLAKSQVRVAVINAQPVGFITCIGHYIDMLFVEPEYTRRGVASALLKPLIK
SESELTVDASITAKPFFERYGFQTVKQQRVECRGTWFTNFYMRYKPQH"
misc_feature 284660..284995
/locus_tag="ECOK1_0257"
/note="Acetyltransferase (GNAT) domain; Region:
Acetyltransf_10; pfam13673"
/db_xref="CDD:205850"
misc_feature 284801..>284929
/locus_tag="ECOK1_0257"
/note="N-Acyltransferase superfamily: Various enzymes that
characteristically catalyze the transfer of an acyl group
to a substrate; Region: NAT_SF; cd04301"
/db_xref="CDD:173926"
misc_feature order(284864..284872,284900..284905)
/locus_tag="ECOK1_0257"
/note="Coenzyme A binding pocket [chemical binding]; other
site"
/db_xref="CDD:173926"
gene 285254..286405
/locus_tag="ECOK1_0258"
/db_xref="GeneID:12688826"
CDS 285254..286405
/locus_tag="ECOK1_0258"
/note="identified by match to protein family HMM PF01139;
match to protein family HMM TIGR03073"
/codon_start=1
/transl_table=11
/product="RtcB protein"
/protein_id="YP_006099504.1"
/db_xref="GI:386597998"
/db_xref="GeneID:12688826"
/translation="MEWYMGKYIRPLSDAVFTIASDDLWIESSAIQQLHTTANLPNMQ
RVVGMPDLHPGRGYPIGAAFFSVGRFYPALVGNDIGCGMALWQTDILARKYNADKFEK
RLSDLDDVAEESWLEENLPSAFAQHPWRNSLGSIGGGNHFAELQQIDQIIDAELFALA
GLDAQHLQLLVHSGSRGLGQSILQRHIASFSHHGLPEGSDDALRYIAEHDDALAFARI
NRQLIALRIMQQVKATGSPVLDVAHNFVSACQIGDQQGWLHRKGATPDDNGLVIIPGS
RGDYSWLVKPVANEKTLHSLAHGAGRKWGRTECKGRLAAKYTATQLSRTELGSRVICR
DKQLIFEEAPQAYKSAESVVQCLVLAGLIIPVARLRPVLTLKNSGGKKG"
misc_feature 285266..286393
/locus_tag="ECOK1_0258"
/note="hypothetical protein; Reviewed; Region: PRK09588"
/db_xref="CDD:181972"
misc_feature 285299..286366
/locus_tag="ECOK1_0258"
/note="Hedgehog/Intein domain, found in Hedgehog proteins
as well as proteins which contain inteins and undergo
protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In
protein splicing an intervening polypeptide sequence - the
intein - is excised from a protein; Region: Hint; cl15780"
/db_xref="CDD:214250"
gene 286402..287016
/locus_tag="ECOK1_0259"
/db_xref="GeneID:12688827"
CDS 286402..287016
/locus_tag="ECOK1_0259"
/note="identified by match to protein family HMM PF00472;
match to protein family HMM TIGR03072"
/codon_start=1
/transl_table=11
/product="peptidyl-tRNA hydrolase domain-containing
protein"
/protein_id="YP_006099505.1"
/db_xref="GI:386597999"
/db_xref="GeneID:12688827"
/translation="MILLQLSSAQGPEECCLAVKKALDRLIKEATRQDVAVTVLETET
GRYSDTLRSALISLDGDNAWALSESWCGTIQWICPSPYRPHHGRKNWFLGIGRFTADE
QEQSDAIRYETLRSSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLL
IAWKLEQQQQENSAALKSQRRMFHHQIERGNPRRTFTGMAFIEG"
misc_feature 286402..287001
/locus_tag="ECOK1_0259"
/note="peptide chain release factor-like protein;
Reviewed; Region: prfH; PRK08179"
/db_xref="CDD:181271"
misc_feature 286405..287004
/locus_tag="ECOK1_0259"
/note="Protein chain release factor B [Translation,
ribosomal structure and biogenesis]; Region: PrfB;
COG1186"
/db_xref="CDD:31379"
gene complement(287073..288530)
/gene="pepD"
/locus_tag="ECOK1_0260"
/db_xref="GeneID:12688828"
CDS complement(287073..288530)
/gene="pepD"
/locus_tag="ECOK1_0260"
/note="identified by similarity to SP:P15288; match to
protein family HMM PF01546; match to protein family HMM
PF07687; match to protein family HMM TIGR01893"
/codon_start=1
/transl_table=11
/product="aminoacyl-histidine dipeptidase"
/protein_id="YP_006099506.1"
/db_xref="GI:386598000"
/db_xref="GeneID:12688828"
/translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDAL
KSLVDTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
misc_feature complement(287082..288512)
/gene="pepD"
/locus_tag="ECOK1_0260"
/note="Xaa-His dipeptidase; Region: aa-his-dipept;
TIGR01893"
/db_xref="CDD:162585"
misc_feature complement(287085..288506)
/gene="pepD"
/locus_tag="ECOK1_0260"
/note="M20 Peptidase D has specificity for
beta-alanyl-L-histidine dipeptide; Region: M20_pepD;
cd03890"
/db_xref="CDD:193510"
misc_feature complement(order(287160..287162,288024..288026,
288093..288098,288186..288188,288303..288305))
/gene="pepD"
/locus_tag="ECOK1_0260"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:193510"
misc_feature complement(order(287385..287390,287397..287402,
287409..287411,287520..287525,287532..287534,
287553..287558,287562..287567,287661..287663,
287673..287675,287832..287834,287862..287864))
/gene="pepD"
/locus_tag="ECOK1_0260"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:193510"
gene 288791..289249
/gene="gpt"
/locus_tag="ECOK1_0261"
/db_xref="GeneID:12688829"
CDS 288791..289249
/gene="gpt"
/locus_tag="ECOK1_0261"
/EC_number="2.4.2.22"
/note="identified by similarity to SP:P0A9M5; match to
protein family HMM PF00156"
/codon_start=1
/transl_table=11
/product="xanthine-guanine phosphoribosyltransferase"
/protein_id="YP_006099507.1"
/db_xref="GI:386598001"
/db_xref="GeneID:12688829"
/translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
MYPKAHFITIFAKPAGRPLVDDYVVDIPQNTWIEQPWDMGVVFVPPISGR"
misc_feature 288884..289177
/gene="gpt"
/locus_tag="ECOK1_0261"
/note="Phosphoribosyl transferase (PRT)-type I domain;
Region: PRTases_typeI; cd06223"
/db_xref="CDD:206754"
misc_feature order(288896..288898,288902..288904,289052..289060,
289064..289078,289133..289135)
/gene="gpt"
/locus_tag="ECOK1_0261"
/note="active site"
/db_xref="CDD:206754"
gene 289341..290585
/gene="frsA"
/locus_tag="ECOK1_0262"
/db_xref="GeneID:12688830"
CDS 289341..290585
/gene="frsA"
/locus_tag="ECOK1_0262"
/note="identified by similarity to SP:P04335; match to
protein family HMM PF06500"
/codon_start=1
/transl_table=11
/product="fermentation-respiration switch protein"
/protein_id="YP_006099508.1"
/db_xref="GI:386598002"
/db_xref="GeneID:12688830"
/translation="MTQANLSETLFKPRFKHPETSTLVRRFSHGAQPPVQSALDGKTI
PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
PVYRNFDKGLQEITDWIEKRLC"
misc_feature 289341..290582
/gene="frsA"
/locus_tag="ECOK1_0262"
/note="fermentation/respiration switch protein; Reviewed;
Region: frsA; PRK05077"
/db_xref="CDD:179925"
gene 290643..291044
/gene="crl"
/locus_tag="ECOK1_0263"
/db_xref="GeneID:12688831"
CDS 290643..291044
/gene="crl"
/locus_tag="ECOK1_0263"
/note="identified by similarity to SP:P24251; match to
protein family HMM PF07417"
/codon_start=1
/transl_table=11
/product="sigma factor-binding protein Crl"
/protein_id="YP_006099509.1"
/db_xref="GI:386598003"
/db_xref="GeneID:12688831"
/translation="MTLPSGHPKSRLVKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWTSVQIKDAEVVERLEHTLRE
FHEKLRELLATLNLKLEPADDFRDEPVKLTA"
misc_feature 290643..291023
/gene="crl"
/locus_tag="ECOK1_0263"
/note="DNA-binding transcriptional regulator Crl;
Provisional; Region: PRK10984"
/db_xref="CDD:182882"
gene complement(291154..292209)
/gene="phoE"
/locus_tag="ECOK1_0264"
/db_xref="GeneID:12688832"
CDS complement(291154..292209)
/gene="phoE"
/locus_tag="ECOK1_0264"
/note="identified by similarity to SP:P02932; match to
protein family HMM PF00267"
/codon_start=1
/transl_table=11
/product="outer membrane pore protein E"
/protein_id="YP_006099510.1"
/db_xref="GI:386598004"
/db_xref="GeneID:12688832"
/translation="MKKSTLALVVMGIVASVSVQAAEIYNKDGNKLDVYGKVKAMHYM
SDNDSKDGDQSYIRFGFKGETQINVQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPISGGFANKTQNFEAVAQYQF
DFGLRPSLGYVLSKGKDIEGIGDEDLVNYVDVGATYYFNKNMSAFVDYKINQLDSDNK
LNINNDDIVAVGMTYQF"
misc_feature complement(291157..292122)
/gene="phoE"
/locus_tag="ECOK1_0264"
/note="Porins form aqueous channels for the diffusion of
small hydrophillic molecules across the outer membrane.
Individual 16-strand anti-parallel beta-barrels form a
central pore, and trimerizes thru mainly hydrophobic
interactions at the interface. Trimers...; Region:
gram_neg_porins; cd00342"
/db_xref="CDD:30071"
misc_feature complement(order(291157..291159,291163..291165,
291169..291171,291256..291258,291265..291270,
291760..291765,291769..291771,291868..291876,
291904..291918,291922..291927,291958..291969,
291973..291975,291979..291987,291991..291993,
292009..292023,292084..292092,292096..292098,
292114..292116,292120..292122))
/gene="phoE"
/locus_tag="ECOK1_0264"
/note="trimer interface [polypeptide binding]; other site"
/db_xref="CDD:30071"
misc_feature complement(order(291769..291771,291829..291831,
291922..291924,292036..292038,292099..292101))
/gene="phoE"
/locus_tag="ECOK1_0264"
/note="eyelet of channel; other site"
/db_xref="CDD:30071"
gene 292498..293601
/gene="proB"
/locus_tag="ECOK1_0265"
/db_xref="GeneID:12688833"
CDS 292498..293601
/gene="proB"
/locus_tag="ECOK1_0265"
/EC_number="2.7.2.11"
/note="identified by match to protein family HMM PF00696;
match to protein family HMM PF01472; match to protein
family HMM TIGR01027"
/codon_start=1
/transl_table=11
/product="glutamate 5-kinase"
/protein_id="YP_006099511.1"
/db_xref="GI:386598005"
/db_xref="GeneID:12688833"
/translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
misc_feature 292498..293592
/gene="proB"
/locus_tag="ECOK1_0265"
/note="gamma-glutamyl kinase; Provisional; Region:
PRK05429"
/db_xref="CDD:235460"
misc_feature 292513..293265
/gene="proB"
/locus_tag="ECOK1_0265"
/note="AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes
glutamate-dependent ATP cleavage; G5K transfers the
terminal phosphoryl group of ATP to the gamma-carboxyl
group of glutamate, in the first and controlling step of
proline (and, in mammals, ornithine)...; Region:
AAK_G5K_ProB; cd04242"
/db_xref="CDD:239775"
misc_feature order(292537..292539,293002..293010,293017..293022,
293128..293130,293134..293136,293146..293148)
/gene="proB"
/locus_tag="ECOK1_0265"
/note="nucleotide binding site [chemical binding]; other
site"
/db_xref="CDD:239775"
misc_feature order(292612..292617,292624..292626,292714..292716,
292726..292728,292795..292797,292801..292803,
292843..292848,292864..292866,292873..292875,
292903..292905,292909..292914)
/gene="proB"
/locus_tag="ECOK1_0265"
/note="homotetrameric interface [polypeptide binding];
other site"
/db_xref="CDD:239775"
misc_feature 292648..292671
/gene="proB"
/locus_tag="ECOK1_0265"
/note="putative phosphate binding site [ion binding];
other site"
/db_xref="CDD:239775"
misc_feature order(292651..292653,292906..292908,292939..292941)
/gene="proB"
/locus_tag="ECOK1_0265"
/note="putative allosteric binding site; other site"
/db_xref="CDD:239775"
misc_feature 293323..293547
/gene="proB"
/locus_tag="ECOK1_0265"
/note="PUA domain; Region: PUA; pfam01472"
/db_xref="CDD:201816"
gene 293613..294866
/gene="proA"
/locus_tag="ECOK1_0266"
/db_xref="GeneID:12688834"
CDS 293613..294866
/gene="proA"
/locus_tag="ECOK1_0266"
/EC_number="1.2.1.41"
/note="identified by match to protein family HMM PF00171;
match to protein family HMM TIGR00407"
/codon_start=1
/transl_table=11
/product="gamma-glutamyl phosphate reductase"
/protein_id="YP_006099512.1"
/db_xref="GI:386598006"
/db_xref="GeneID:12688834"
/translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSESILN
ANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSG
LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
TGGIGVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
MAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
ARGPMGLEALTTYKWIGIGDYTIRA"
misc_feature 293619..294848
/gene="proA"
/locus_tag="ECOK1_0266"
/note="Gamma-glutamyl phosphate reductase (GPR), aldehyde
dehydrogenase families 18 and 19; Region:
ALDH_F18-19_ProA-GPR; cd07079"
/db_xref="CDD:143398"
misc_feature 293637..294830
/gene="proA"
/locus_tag="ECOK1_0266"
/note="gamma-glutamyl phosphate reductase; Region: proA;
TIGR00407"
/db_xref="CDD:161862"
misc_feature 294369..294371
/gene="proA"
/locus_tag="ECOK1_0266"
/note="putative catalytic cysteine [active]"
/db_xref="CDD:143398"
gene 294981..295056
/locus_tag="ECOK1_0267"
/db_xref="GeneID:12688835"
tRNA 294981..295056
/locus_tag="ECOK1_0267"
/product="tRNA-Thr"
/db_xref="GeneID:12688835"
gene 295211..295549
/locus_tag="ECOK1_0268"
/db_xref="GeneID:12688836"
CDS 295211..295549
/locus_tag="ECOK1_0268"
/codon_start=1
/transl_table=11
/product="integrase"
/protein_id="YP_006099513.1"
/db_xref="GI:386598007"
/db_xref="GeneID:12688836"
/translation="MKLNARQIDTAKPKEKAYKLADGGGLYLLVKPGGGEYWRLKYRV
AGKEKLLALGVYPEVTLADAPAKLEEAKRGISGGIDLMEVKREEKIARETQLNNTFKD
IALEWHSNKL"
misc_feature 295217..295477
/locus_tag="ECOK1_0268"
/note="Domain of unknown function (DUF4102); Region:
DUF4102; pfam13356"
/db_xref="CDD:222069"
gene complement(295984..296478)
/locus_tag="ECOK1_0269"
/db_xref="GeneID:12688837"
CDS complement(295984..296478)
/locus_tag="ECOK1_0269"
/note="identified by match to protein family HMM PF01047"
/codon_start=1
/transl_table=11
/product="MarR family transcriptional regulator"
/protein_id="YP_006099514.1"
/db_xref="GI:386598008"
/db_xref="GeneID:12688837"
/translation="MNNIDLLKTITNYKKIKNPAYPAQESLLIHLYIRVNDKIQSIIE
NELSEYRINTSTFMVLVSLYMSDDYCQSPSDIYKELQFSKTNITHIIDKLEKKNIAKR
INNKNDRRSKSICLTPDGVTLAQKLINTQNVMLKKIWSGLSDDEMKTFELANKKLLSN
LNVN"
misc_feature complement(295993..296445)
/locus_tag="ECOK1_0269"
/note="Helix-turn-helix domains; Region: HTH; cl00088"
/db_xref="CDD:214025"
misc_feature complement(296038..296346)
/locus_tag="ECOK1_0269"
/note="helix_turn_helix multiple antibiotic resistance
protein; Region: HTH_MARR; smart00347"
/db_xref="CDD:197670"
gene complement(296634..300764)
/gene="hbp"
/locus_tag="ECOK1_0270"
/db_xref="GeneID:12688838"
CDS complement(296634..300764)
/gene="hbp"
/locus_tag="ECOK1_0270"
/EC_number="3.4.21.-"
/note="identified by similarity to SP:O88093; match to
protein family HMM PF02395; match to protein family HMM
PF03797; match to protein family HMM TIGR01414"
/codon_start=1
/transl_table=11
/product="hemoglobin-binding protease Hbp"
/protein_id="YP_006099515.1"
/db_xref="GI:386598009"
/db_xref="GeneID:12688838"
/translation="MNKIYALKYCYITNTVKVVSELARRVCKGSTRRGKRLSVLTSLA
LSALLPTVAGASTVGGNNPYQTYRDFAENKGQFQAGATNIPIFNNKGELVGHLDKAPM
VDFSSVNVSSNPGVATLINPQYIASVKHNKGYQSVSFGDGQNSYHIVDRNEHSSSDLH
TPRLDKLVTEVAPATVTSSSTADILNPSKYSAFYRAGSGSQYIQDSQGKRHWVTGGYG
YLTGGILPTSFFYHGSDGIQLYMGGNIHDHSILPSFGEAGDSGSPLFGWNTAKGQWEL
VGVYSGVGGGTNLIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPLQWKFDSSTGTGSL
KQGSDEYAMHGQKGSDLNAGKNLTFLGHNGQIDLENSVTQGAGSLTFTDDYTVTTSNG
STWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLN
QQADSSGHVQAFSSVNIASGRPTVVLADNQQVNPDNISWGYRGGVLDVNGNDLTFHKL
NAADYGATLGNSSDKTANITLDYQTRPADVKVNEWSSSNRGTVGSLYIYNNPYTHTVD
YFILKTSSYGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGYLYHGKLLGNINFS
NKATPGTTGALVMDGSANMSGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSV
LTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRNATLNTTIQADNSSVTLGDSRVFID
KKDGQGTAFTLEEGTSVATKDADKSVFNGTVNLDNQSVLNINEIFNGGIQANNSTVNI
SSDSAVLENSTLTSTALNLNKGANVLASQSFVSDGPVNISDATLSLNSRPDEVSHTLL
PVYDYAGSWNLKGDDARLNVGPYSMLSGNINVQDKGTVTLGGEGELSPDLTLQNQMLY
SLFNGYRNTWSGSLNAPDATVSMTDTQWSMNGNSTAGNMKLNRTIVGFNGGTSSFTTL
TTDNLDAVQSAFVMRTDLNKADKLVINKSATGHDNSIWVNFLKKPSDKDTLDIPLVSA
PEATADNLFRASTRVVGFSDVTPTLSVRKEDGKKEWVLDGYQVARNDGQGKAAATFMH
ISYNNFITEVNNLNKRMGDLRDINGEAGTWVRLLNGSGSADGGFTDHYTLLQMGADRK
HELGSMDLFTGVMATYTDTDASAGLYSGKTKSWGGGFYASGLFRSGAYFDLIAKYIHN
ENKYDLNFAGAGKQNFRSHSLYAGAEVGYRYHLTDTTFVEPQAELVWGRLQGQTFNWN
DSGMDVSMRRNSVNPLVGRTGVVSGKTFSGKDWSLTGRAGLHYEFDLTDSADVHLKDA
AGEHQINGRKDGRMLYGVGLNARFGDNTRLGLEVERSAFGKYNTDDAINANIRYSF"
misc_feature complement(300693..300764)
/gene="hbp"
/locus_tag="ECOK1_0270"
/note="Extended Signal Peptide of Type V secretion system;
Region: ESPR; pfam13018"
/db_xref="CDD:205199"
misc_feature complement(298338..300578)
/gene="hbp"
/locus_tag="ECOK1_0270"
/note="Immunoglobulin A1 protease; Region: Peptidase_S6;
pfam02395"
/db_xref="CDD:202230"
misc_feature complement(297540..298205)
/gene="hbp"
/locus_tag="ECOK1_0270"
/note="Pertactin-like passenger domains (virulence
factors), C-terminal, subgroup 1, of autotransporter
proteins of the type V secretion system of Gram-negative
bacteria. This subgroup includes the passenger domains of
Neisseria and Haemophilus IgA1 proteases; Region:
PL1_Passenger_AT; cd01343"
/db_xref="CDD:29328"
misc_feature complement(296637..297872)
/gene="hbp"
/locus_tag="ECOK1_0270"
/note="outer membrane autotransporter barrel domain;
Region: autotrans_barl; TIGR01414"
/db_xref="CDD:162346"
misc_feature complement(296676..297431)
/gene="hbp"
/locus_tag="ECOK1_0270"
/note="Autotransporter beta-domain; Region:
Autotransporter; pfam03797"
/db_xref="CDD:202770"
gene 301874..302050
/locus_tag="ECOK1_0271"
/note="conserved domain protein; this gene contains a
frame shift which may be the result of a sequencing error;
identified by match to protein family HMM PF03400"
/pseudo
/db_xref="GeneID:12688839"
gene 302474..302659
/locus_tag="ECOK1_0272"
/db_xref="GeneID:12688840"
CDS 302474..302659
/locus_tag="ECOK1_0272"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099516.1"
/db_xref="GI:386598010"
/db_xref="GeneID:12688840"
/translation="MASGLICHGGFKPHAWGVASLMDVTVLVVASLLVWLLVNRENHY
ARGIPQDVQVLHKKAHH"
gene 302874..303488
/locus_tag="ECOK1_0273"
/db_xref="GeneID:12688841"
CDS 302874..303488
/locus_tag="ECOK1_0273"
/note="identified by similarity to GB:CAG73364.1; match to
protein family HMM PF07274"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099517.1"
/db_xref="GI:386598011"
/db_xref="GeneID:12688841"
/translation="MNIFEQTPPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSP
VDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRDWLGLTDPNSAVYTFAGHVFNWV
GVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDL
PWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR"
misc_feature 302880..303473
/locus_tag="ECOK1_0273"
/note="Predicted periplasmic/secreted protein [Function
unknown]; Region: COG3477"
/db_xref="CDD:226008"
gene 303786..303911
/locus_tag="ECOK1_0274"
/db_xref="GeneID:12688842"
CDS 303786..303911
/locus_tag="ECOK1_0274"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099518.1"
/db_xref="GI:386598012"
/db_xref="GeneID:12688842"
/translation="MTSPFSPDMANSLHVDDRFSYIVQQAFLPGVPARAIHRGFF"
gene complement(303922..304035)
/locus_tag="ECOK1_0275"
/db_xref="GeneID:12688843"
CDS complement(303922..304035)
/locus_tag="ECOK1_0275"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099519.1"
/db_xref="GI:386598013"
/db_xref="GeneID:12688843"
/translation="MPVVHFSASLFTGPKPTMLAVPFPPGSLNKYPLFTDA"
gene complement(304373..305083)
/locus_tag="ECOK1_0276"
/db_xref="GeneID:12688844"
CDS complement(304373..305083)
/locus_tag="ECOK1_0276"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099520.1"
/db_xref="GI:386598014"
/db_xref="GeneID:12688844"
/translation="MFRRRGVTLTKALLTVVCMLAAPLTQAISVGNLTFSLPSETDFV
SKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFY
YHGPRDNRERYYRVSFREVPTRNLTKRSPSGGEVSTEPVVVMDTILVVRPRQVQFKWS
FDQVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYN
DKFIKISDSCPAKPPSAD"
gene complement(305052..306695)
/locus_tag="ECOK1_0277"
/db_xref="GeneID:12688845"
CDS complement(305052..306695)
/locus_tag="ECOK1_0277"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099521.1"
/db_xref="GI:386598015"
/db_xref="GeneID:12688845"
/translation="MRVNLLIAMIIFALIWPATALRAAVSKTTWADAPAREFVFVENN
SDDNFFVTPGGALDPRLTGANRWTGLKYNGSGTIYQQSLGYIDNGYNTGLYTNWKFDM
WLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDASGFYGATVTSGGAKWMHGMLS
DAFYQYLQQMPVGSSFTMTINACQTSVNYDANSGARCKDQASGNWYVRNVTHTKAANL
RLINTHSLAEVFINSDGVPTLGEGNADCRTQTIGSRSGLSCKMVNYTLQTNGLSNTSI
HIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEMKSADSIYVFFSSNF
FKQMVNLGISDINTKDLFNFRFQNTTSPESGWYEFSTSNTLIIKPRDFSISIISDEYT
QTPSREGYVGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGK
AKVPFPATLSFITRNGATKTYDAGCDDSWRDMTDALWLTTPWTDISGEVGQMDKTTVK
FSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN"
gene complement(306685..309210)
/locus_tag="ECOK1_0278"
/db_xref="GeneID:12688846"
CDS complement(306685..309210)
/locus_tag="ECOK1_0278"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099522.1"
/db_xref="GI:386598016"
/db_xref="GeneID:12688846"
/translation="MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQ
AFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASV
SEQTRQQLMTLANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSED
IGQSSVNTLSSNLSYNFGVYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIG
SGQQDSELYKAMYERDFAGHRFAGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASST
IFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEV
IVNGRVISKRTQRVNKLFSRGRGVGAPLAWQIWGGSFHMDRWSENGKKTRPAKESWLA
GASTSGSLSTFSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSNIASI
SATLPGGFSSLWVNQEKTRIGNQLRRSDADNRAIGGTLNLNSLWSKLGTFSISYNDDR
RYNSHYYTADYYQSVYSGTFGSLGLRAGIQRYNNGDSSANTGKYIALDLSLPLGNWFS
AGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARY
ASGTLNVNSAADGYINTNLTANGSVGWQGKNIAASGRTDGNAGVIFDTGLENDGQISA
KINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSYDIVSGRKSHLTLYPGNVAVI
EPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYS
GNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES"
misc_feature complement(307231..>307788)
/locus_tag="ECOK1_0278"
/note="Type VII secretion system (T7SS), usher protein;
Region: Usher; pfam00577"
/db_xref="CDD:216001"
misc_feature complement(<306781..306966)
/locus_tag="ECOK1_0278"
/note="Peptidase associated domain: C-terminal domain of
M14 N/E carboxypeptidase; putative folding, regulation, or
interaction domain; Region: Peptidase_M14NE-CP-C_like;
cl17499"
/db_xref="CDD:248053"
gene complement(309236..309904)
/locus_tag="ECOK1_0279"
/db_xref="GeneID:12688847"
CDS complement(309236..309904)
/locus_tag="ECOK1_0279"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099523.1"
/db_xref="GI:386598017"
/db_xref="GeneID:12688847"
/translation="MKKHLLPLALLFSGISPAQALDVGDISSFMNSDSSTLSKTIQNS
TDSGRLINIRLERLSSPLDDGQVIAMDKPDELLLTPASLLLPAQASEVIRFFYKGPAD
EKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGSLT
NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTHVDTADNKGRVALWQGDKF
IPVK"
gene complement(309961..310548)
/gene="matB"
/locus_tag="ECOK1_0280"
/db_xref="GeneID:12688848"
CDS complement(309961..310548)
/gene="matB"
/locus_tag="ECOK1_0280"
/note="identified by similarity to GB:AAK01671.1"
/codon_start=1
/transl_table=11
/product="fimbrillin MatB"
/protein_id="YP_006099524.1"
/db_xref="GI:386598018"
/db_xref="GeneID:12688848"
/translation="MKKKVLAIALVTVFTGTGVAQAADVTAQAVATWSATAKKDTTSK
LVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSG
STLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSII
SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS"
gene complement(310622..311212)
/gene="matA"
/locus_tag="ECOK1_0281"
/db_xref="GeneID:12688849"
CDS complement(310622..311212)
/gene="matA"
/locus_tag="ECOK1_0281"
/note="identified by similarity to GB:AAK01670.1; match to
protein family HMM PF00196"
/codon_start=1
/transl_table=11
/product="fimbrillin MatA"
/protein_id="YP_006099525.1"
/db_xref="GI:386598019"
/db_xref="GeneID:12688849"
/translation="MTWQNDYSRDYEVKNHMECQNRSDKYIWSPHDAYFYKGLSELIV
DIDRLIYLSLEKIRKDFVFINLNTDSLTEFINRDNEWLSAVKGKQVVLIAARKSEALA
NYWYYNSNIRGVVYAGLSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGM
LPKSIARIENCSVKTVYTHRRNAEAKLYSKLYKLVQ"
misc_feature complement(310652..>310777)
/gene="matA"
/locus_tag="ECOK1_0281"
/note="Response regulator containing a CheY-like receiver
domain and an HTH DNA-binding domain [Signal transduction
mechanisms / Transcription]; Region: CitB; COG2197"
/db_xref="CDD:32379"
misc_feature complement(<310652..310777)
/gene="matA"
/locus_tag="ECOK1_0281"
/note="C-terminal DNA-binding domain of LuxR-like
proteins. This domain contains a helix-turn-helix motif
and binds DNA. Proteins belonging to this group are
response regulators; some act as transcriptional
activators, others as transcriptional repressors. Many...;
Region: LuxR_C_like; cd06170"
/db_xref="CDD:99777"
misc_feature complement(order(310670..310684,310688..310693,
310697..310702,310724..310732,310769..310777))
/gene="matA"
/locus_tag="ECOK1_0281"
/note="DNA binding residues [nucleotide binding]"
/db_xref="CDD:99777"
gene complement(312248..312388)
/gene="rpmJ"
/locus_tag="ECOK1_0282"
/db_xref="GeneID:12688850"
CDS complement(312248..312388)
/gene="rpmJ"
/locus_tag="ECOK1_0282"
/note="identified by match to protein family HMM PF00444;
match to protein family HMM TIGR01022"
/codon_start=1
/transl_table=11
/product="50S ribosomal protein L36"
/protein_id="YP_006099526.1"
/db_xref="GI:386598020"
/db_xref="GeneID:12688850"
/translation="MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKK
KR"
misc_feature complement(312266..312388)
/gene="rpmJ"
/locus_tag="ECOK1_0282"
/note="50S ribosomal protein L36; Validated; Region: rpmJ;
PRK00831"
/db_xref="CDD:179138"
gene complement(312388..312654)
/gene="rpmE2"
/locus_tag="ECOK1_0283"
/db_xref="GeneID:12688851"
CDS complement(312388..312654)
/gene="rpmE2"
/locus_tag="ECOK1_0283"
/note="identified by match to protein family HMM PF01197;
match to protein family HMM TIGR00105"
/codon_start=1
/transl_table=11
/product="50S ribosomal protein L31"
/protein_id="YP_006099527.1"
/db_xref="GI:386598021"
/db_xref="GeneID:12688851"
/translation="MMKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYP
YVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA"
misc_feature complement(312394..312651)
/gene="rpmE2"
/locus_tag="ECOK1_0283"
/note="50S ribosomal protein L31 type B; Reviewed; Region:
rpmE2; PRK01678"
/db_xref="CDD:234969"
gene complement(313591..314733)
/locus_tag="ECOK1_0284"
/db_xref="GeneID:12688852"
CDS complement(313591..314733)
/locus_tag="ECOK1_0284"
/note="identified by match to protein family HMM PF00724"
/codon_start=1
/transl_table=11
/product="oxidoreductase FAD/FMN-binding protein"
/protein_id="YP_006099528.1"
/db_xref="GI:386598022"
/db_xref="GeneID:12688852"
/translation="MTNKHPSLFSPFMLTEKIKLRNRIVMAPMTTWSANPDGTISEQE
LEFYKRRSQNVGLVITGCTYVTPSGIGFTHEFAAYDDRFINSLEKLAAAAKSGGAPAI
LQIFHAGNKAIPELVPNNDVISASASSVKSGDFMKRVVQSREMTENEIQETIRAFGDV
TKRAIKAGFDGVELHGAHGFLLQNFFSPLFNQRNDRWGGDLEGRMRFPLAVLQEVKNV
VYEYATKPFAIGYRISPEESVTGGLRIEDTYKLLDRLISSGISYIHTSLVSINDSYPV
ESPNGPRTIELILNHIAGRVPVIAAGKIRTPSQAQEAISAGLPLVAIGKGLVINPEWV
TLAESGRSHEIQTALNPQRVPELTIPDKLWDQIQASKGTGWFPLMD"
misc_feature complement(313642..314712)
/locus_tag="ECOK1_0284"
/note="Old yellow enzyme (OYE)-related FMN binding domain,
group 4. Each monomer of OYE contains FMN as a
non-covalently bound cofactor, uses NADPH as a reducing
agent with oxygens, quinones, and alpha,beta-unsaturated
aldehydes and ketones, and can act as...; Region:
OYE_like_4_FMN; cd04735"
/db_xref="CDD:73397"
misc_feature complement(order(313759..313764,314026..314028,
314194..314196,314422..314424,314548..314550,
314644..314646,314650..314652))
/locus_tag="ECOK1_0284"
/note="putative active site [active]"
/db_xref="CDD:73397"
misc_feature complement(order(313759..313764,314026..314028,
314422..314424,314548..314550,314644..314646,
314650..314652))
/locus_tag="ECOK1_0284"
/note="putative FMN binding site [chemical binding]; other
site"
/db_xref="CDD:73397"
misc_feature complement(order(314194..314196,314200..314202))
/locus_tag="ECOK1_0284"
/note="putative substrate binding site [chemical binding];
other site"
/db_xref="CDD:73397"
misc_feature complement(314194..314196)
/locus_tag="ECOK1_0284"
/note="putative catalytic residue [active]"
/db_xref="CDD:73397"
gene complement(314905..315825)
/locus_tag="ECOK1_0285"
/db_xref="GeneID:12688853"
CDS complement(314905..315825)
/locus_tag="ECOK1_0285"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099529.1"
/db_xref="GI:386598023"
/db_xref="GeneID:12688853"
/translation="MKTVSIKHTYWDIAADIYFPDDFNSEKKYPAIISAHPIGSCKEQ
TSGSVYGAALAKAGFIVIAFDASFQGSSGGEPRYLEDPTMRVKDFSIVVDYLTTLPYV
DAGRIGVLGICGGGGYAINAAMTERRIKAIGTVTGANYGRLMREGFTAFNPIGALEAM
AQQRTDEANGAKLRVDDLLPSSPEAALEAGLTEIDLFEATEYYRSPRGCAPNGVNRSL
FSHQTVAVGWDAFHLAEVLLTQPLMVVVGDRVGAFGAYRDGCEIIGRAASKHKELVVV
EGYSHYDLYDKPEPVKQALDKLIPFYKTHL"
misc_feature complement(314908..315804)
/locus_tag="ECOK1_0285"
/note="Hydrolases of the alpha/beta superfamily [General
function prediction only]; Region: COG1073"
/db_xref="CDD:223999"
gene 315919..316908
/locus_tag="ECOK1_0286"
/db_xref="GeneID:12688854"
CDS 315919..316908
/locus_tag="ECOK1_0286"
/note="identified by match to protein family HMM PF00126;
match to protein family HMM PF03466"
/codon_start=1
/transl_table=11
/product="LysR family transcriptional regulator"
/protein_id="YP_006099530.1"
/db_xref="GI:386598024"
/db_xref="GeneID:12688854"
/translation="MTCIGYHQWSNIYHSVKLRFTMMKIEPSILPSLAWFALIVRAGS
FSRAASEMGITRAALSQNLKSLEERLNTKLIYRTTRNMSLTEEGQHLYEVLVSALGQI
DDALKDVGDTQLEPTGLLRINSSRVAARMLVEPHIGEFLTRYPKTKIELIMDDGLSNI
IADGCDVGIRLEQGLDEHMTAVPVSPLIKLVTVASPDYLKEHGIPETPQELSNHNCLR
LRHKSSGALSAWEFSNVVGGNEEFEIEVSGKYISNDDESMIRMALNGTGIIQHLDFAI
AEHINAGKLQPILEDWAVSFPGFYIYVSSRVRMPSKVRAFIDFMVEKRVKIES"
misc_feature 316006..316884
/locus_tag="ECOK1_0286"
/note="Transcriptional regulator [Transcription]; Region:
LysR; COG0583"
/db_xref="CDD:30928"
misc_feature 316015..316185
/locus_tag="ECOK1_0286"
/note="Bacterial regulatory helix-turn-helix protein, lysR
family; Region: HTH_1; pfam00126"
/db_xref="CDD:201021"
misc_feature 316264..316878
/locus_tag="ECOK1_0286"
/note="The C-terminal substrate binding domain of an
uncharacterized LysR-type transcriptional regulator
CrgA-like, contains the type 2 periplasmic binding fold;
Region: PBP2_CrgA_like_5; cd08474"
/db_xref="CDD:176163"
misc_feature order(316300..316302,316312..316314,316429..316431,
316471..316473,316480..316482,316681..316683,
316732..316734,316813..316815)
/locus_tag="ECOK1_0286"
/note="putative effector binding pocket; other site"
/db_xref="CDD:176163"
misc_feature order(316303..316308,316318..316323,316327..316332,
316339..316341,316351..316353,316357..316377,
316561..316563,316663..316677,316696..316701,
316708..316710)
/locus_tag="ECOK1_0286"
/note="putative dimerization interface [polypeptide
binding]; other site"
/db_xref="CDD:176163"
gene 317108..318001
/locus_tag="ECOK1_0287"
/db_xref="GeneID:12688855"
CDS 317108..318001
/locus_tag="ECOK1_0287"
/note="identified by match to protein family HMM PF00126;
match to protein family HMM PF03466"
/codon_start=1
/transl_table=11
/product="LysR family transcriptional regulator"
/protein_id="YP_006099531.1"
/db_xref="GI:386598025"
/db_xref="GeneID:12688855"
/translation="MLKENFNELQIFLVVARERSFTKAAGKLGVSQSALSHAMKALEE
RLNIRLLTRTTRSVAPTEAGERIIACLEPRIDELEQELESLIQLNGTPSGNIRLSAGE
HAARSLVWPKLKPFLREYPEINVELVVDNGFVDIVEGRFDAGIRLGENVDKDMVAVRI
GPDMRMAVVGAPAYFAANPAPETPHELQNHRCINMRLPTAGGLYHWEFEREGKPLRVK
VDGQLTCSPLPERIDAALSGFGIACVPEDMVQEYIESGKLIQVLQEWCPTFPGYYLYY
PSRKQHPPAFALLIDALRYTE"
misc_feature 317120..317989
/locus_tag="ECOK1_0287"
/note="Transcriptional regulator [Transcription]; Region:
LysR; COG0583"
/db_xref="CDD:223656"
misc_feature 317123..317302
/locus_tag="ECOK1_0287"
/note="Bacterial regulatory helix-turn-helix protein, lysR
family; Region: HTH_1; pfam00126"
/db_xref="CDD:215735"
misc_feature 317381..317986
/locus_tag="ECOK1_0287"
/note="The C-terminal substrate binding domain of an
uncharacterized LysR-type transcriptional regulator
CrgA-like, contains the type 2 periplasmic binding fold;
Region: PBP2_CrgA_like_5; cd08474"
/db_xref="CDD:176163"
misc_feature order(317417..317419,317429..317431,317546..317548,
317588..317590,317597..317599,317789..317791,
317840..317842,317921..317923)
/locus_tag="ECOK1_0287"
/note="putative effector binding pocket; other site"
/db_xref="CDD:176163"
misc_feature order(317420..317425,317435..317440,317444..317449,
317456..317458,317468..317470,317474..317494,
317678..317680,317771..317785,317804..317809,
317816..317818)
/locus_tag="ECOK1_0287"
/note="putative dimerization interface [polypeptide
binding]; other site"
/db_xref="CDD:176163"
gene complement(318032..319021)
/locus_tag="ECOK1_0288"
/db_xref="GeneID:12688856"
CDS complement(318032..319021)
/locus_tag="ECOK1_0288"
/note="identified by match to protein family HMM PF00248"
/codon_start=1
/transl_table=11
/product="oxidoreductase, aldo/keto reductase family"
/protein_id="YP_006099532.1"
/db_xref="GI:386598026"
/db_xref="GeneID:12688856"
/translation="MQKRYLGKSGLEVSALGLGCMGLSHGYGPATDTRQAIELIRAAI
ERGVTFFDTAEVYGPYLNEEVVGEALKPFRDRVVIATKFGFTFGDDNKQQILNSRPEH
IREAVEGSLRRLKTDVIDLLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQ
TIRRAHAVQPVTALQSEYSMWWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKPG
TTFGKDDYRSTVPRFAAQAIEANEKLVTLLGELAAEKGVTSAQIALAWLLAQKPWIVP
IPGTTKLHRLEENLAAADIVLSQKDTQQISEALETIKIVGERYSPEHQARVGR"
misc_feature complement(318071..319021)
/locus_tag="ECOK1_0288"
/note="Predicted oxidoreductases (related to aryl-alcohol
dehydrogenases) [Energy production and conversion];
Region: Tas; COG0667"
/db_xref="CDD:31011"
misc_feature complement(318098..319015)
/locus_tag="ECOK1_0288"
/note="Aldo-keto reductases (AKRs) are a superfamily of
soluble NAD(P)(H) oxidoreductases whose chief purpose is
to reduce aldehydes and ketones to primary and secondary
alcohols. AKRs are present in all phyla and are of
importance to both health and industrial...; Region:
Aldo_ket_red; cd06660"
/db_xref="CDD:119408"
misc_feature complement(order(318155..318160,318167..318169,
318182..318193,318242..318244,318398..318415,
318497..318499,318554..318559,318644..318649,
318776..318778,318851..318853,318866..318868,
318959..318967))
/locus_tag="ECOK1_0288"
/note="active site"
/db_xref="CDD:119408"
misc_feature complement(order(318647..318649,318776..318778,
318851..318853,318866..318868))
/locus_tag="ECOK1_0288"
/note="catalytic tetrad [active]"
/db_xref="CDD:119408"
gene complement(319048..319899)
/locus_tag="ECOK1_0289"
/db_xref="GeneID:12688857"
CDS complement(319048..319899)
/locus_tag="ECOK1_0289"
/note="identified by match to protein family HMM PF00248"
/codon_start=1
/transl_table=11
/product="oxidoreductase, aldo/keto reductase family"
/protein_id="YP_006099533.1"
/db_xref="GI:386598027"
/db_xref="GeneID:12688857"
/translation="MQKVKLNNGIEMPLLGFGVFQMTDAAECERAVIDAINSGYRLID
TAASYQNEIQVGNALKQSGIARNELFVTTKLWLQDTSYEGAKAQFERSLNRLQLDYVD
LYLIHQPYGDVHGAWRAMEELQQAGKIRAIGVSNFHPDRLADLIAFNNVVPAVNQVEV
NPFNQQLQAVPWMQSRGIQPEAWAPFAEGKNGLFQHPVLTAIGEKYGKSVGQVVLRWI
YQRGIVSLAKSVRKERMEENINILDFELSPEDMLQITALDTATSAFFSHRDPAMVEWL
TGRKLDV"
misc_feature complement(319129..319893)
/locus_tag="ECOK1_0289"
/note="Aldo-keto reductases (AKRs) are a superfamily of
soluble NAD(P)(H) oxidoreductases whose chief purpose is
to reduce aldehydes and ketones to primary and secondary
alcohols. AKRs are present in all phyla and are of
importance to both health and industrial...; Region:
Aldo_ket_red; cd06660"
/db_xref="CDD:119408"
misc_feature complement(319126..319857)
/locus_tag="ECOK1_0289"
/note="Aldo/keto reductase family; Region: Aldo_ket_red;
pfam00248"
/db_xref="CDD:201112"
misc_feature complement(order(319186..319191,319198..319200,
319213..319224,319267..319269,319336..319353,
319429..319431,319492..319497,319576..319581,
319678..319680,319753..319755,319768..319770,
319840..319848))
/locus_tag="ECOK1_0289"
/note="active site"
/db_xref="CDD:119408"
misc_feature complement(order(319579..319581,319678..319680,
319753..319755,319768..319770))
/locus_tag="ECOK1_0289"
/note="catalytic tetrad [active]"
/db_xref="CDD:119408"
gene 320465..324715
/locus_tag="ECOK1_0290"
/db_xref="GeneID:12688858"
CDS 320465..324715
/locus_tag="ECOK1_0290"
/note="identified by match to protein family HMM PF02369"
/codon_start=1
/transl_table=11
/product="bacterial Ig-like domain (group 1) protein"
/protein_id="YP_006099534.1"
/db_xref="GI:386598028"
/db_xref="GeneID:12688858"
/translation="MSRYKTDNKQPRFRYSVLARCVAWANISVQVLFPLAVTFTPVMA
ARAQHAVQPRLSMENTTVTADNNVEKNVASLAANAGTFLSSQPDSDATRNFITGMATA
KANQEIQEWLGKYGTARVKLNVDKNFSLKDSSLEMLYPIYDTPTNMLFTQGAIHRTDD
RTQSNIGFGWRHFSENDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGYIRA
SGWKKSPDVEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQK
DPHAITAEVNYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLEKQLDTDSIRE
RRMLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTVSLGLVVSKATHGLK
NVQWEAPSLLAAGGKITGQGNQWQVTLPAYQAGKDNYYAISAIAYDNKGNASKRVQTE
VVISGAGMSADRTALTLDGQSRIQMLANGNEQKPLVLSLRDAEGQPVTGMKDQIKTEL
TFKPAGNIVTRTLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDDMS
KTVTAELRATMMDVSNSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLR
LVPQDTNGVTVGAISEIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP
LDAAHSSITLNPDKPVVGGTVTAIWTAKDANDNPVTGLNPDAPSLSGAAAAGSTASGW
TDNGDGTWTAQISLGTTAGELDVMPKLNGQDAAANAAKVTVVADALSSNQSKVSVAED
HVKAGESTTVTLVAKDAHGNAISGLSLSASLTGTASEGATVSSWTEKGDGSYVATLTT
GGKTGELRVMPLFNGQPAATEAAQLTVIAGEMSSANSTLVADNKTPTVKTTTELTFTM
KDAYGNPVTGLKPDAPVFSGAASTGSERPSAGNWTEKGNGVYVSTLTLGSAAGQLSVM
PRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVNNQLANGQSANQITLTVVDSYGNPL
QGQEVTLTLPQGVTSKTGNTVTTNAAGKVDIELMSTVAGELEIEASVKNSQKTVKVKF
KADFSTGQASLEVDAAAQKVANGKDAFTLTATVKDQYGNLLPGAVVVFNLPRGVKPLA
DGNIMVNADKEGKAELKVVSVTAGTYEITASAGNDQPSNAQSVTFVADKTTATISSIE
VIGNRAVADGKTKQTYKVTVTDANNNLLKDSEVTLTASPENLVLTPNGTATTNEQGQA
IFTATTTVAATYTLTAKVEQADGQESTKTAESKFVADDKNAVLAASPERVDSLVADGK
TTATLTVTLMSGVNPVGGTMWVDIEAPEGVTEADYQFLPSKNDHFASGKITRTFSTNK
PGTYTFTFNSLTYGGYEMKPVTVTINAVPADTEGAEEK"
misc_feature 320672..321514
/locus_tag="ECOK1_0290"
/note="Protein of unknown function (DUF3442); Region:
DUF3442; pfam11924"
/db_xref="CDD:152359"
misc_feature 322211..322486
/locus_tag="ECOK1_0290"
/note="Bacterial Ig-like domain (group 1); Region: BID_1;
smart00634"
/db_xref="CDD:197809"
misc_feature 323489..323722
/locus_tag="ECOK1_0290"
/note="Bacterial Ig-like domain (group 1); Region: BID_1;
smart00634"
/db_xref="CDD:197809"
misc_feature 323786..324028
/locus_tag="ECOK1_0290"
/note="Bacterial Ig-like domain (group 1); Region: BID_1;
smart00634"
/db_xref="CDD:197809"
misc_feature 324059..>324256
/locus_tag="ECOK1_0290"
/note="Bacterial Ig-like domain (group 1); Region: BID_1;
smart00634"
/db_xref="CDD:197809"
gene complement(324840..325697)
/locus_tag="ECOK1_0291"
/db_xref="GeneID:12688859"
CDS complement(324840..325697)
/locus_tag="ECOK1_0291"
/note="identified by match to protein family HMM PF00165;
match to protein family HMM PF06445"
/codon_start=1
/transl_table=11
/product="AraC family transcriptional regulator"
/protein_id="YP_006099535.1"
/db_xref="GI:386598029"
/db_xref="GeneID:12688859"
/translation="MIRQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN
FMHVPLGEYIRKRRLCRAAILVRLSAKSMLDIALSLHFDSQQSFSREFKKLFGCSPRE
YRHRDYWDLANIFPSFLIRQQQKTECRLVNFPETPIFGNSFKYDIEVSNKLPDEEVKL
RRHHLVRCMKNFKTDIYFVSTFEPSTKSVDLLTVETFAGTVCKQTDSEMPKEWTINRG
LYASFRYEGEWEHYPEWARNLYLMELPARGLARVNGSDIERFYYNENFVEIDSNNIVC
EIFIPVRPV"
misc_feature complement(324849..325697)
/locus_tag="ECOK1_0291"
/note="right oriC-binding transcriptional activator;
Provisional; Region: PRK15121"
/db_xref="CDD:185076"
misc_feature complement(325383..>325484)
/locus_tag="ECOK1_0291"
/note="Bacterial regulatory helix-turn-helix proteins,
AraC family; Region: HTH_AraC; pfam00165"
/db_xref="CDD:215763"
misc_feature complement(324849..325319)
/locus_tag="ECOK1_0291"
/note="Bacterial transcription activator, effector binding
domain; Region: AraC_E_bind; smart00871"
/db_xref="CDD:214874"
gene 325945..326814
/locus_tag="ECOK1_0292"
/db_xref="GeneID:12688860"
CDS 325945..326814
/locus_tag="ECOK1_0292"
/note="identified by match to protein family HMM PF00248"
/codon_start=1
/transl_table=11
/product="oxidoreductase, aldo/keto reductase family"
/protein_id="YP_006099536.1"
/db_xref="GI:386598030"
/db_xref="GeneID:12688860"
/translation="MEFSVLSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLID
TAAVYGNEDAVGEAVREAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSG
LEYFDLYLLHQAMRDYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMV
NQVELHPYFAQPEALATMKYYNVQPEAWAPLGGGRHKPFENNLLQSIADAHQKSISQV
ILRWNIQRGVVVIPKSTHQQRIEENFAIWDFSLTEKEMAQISSLDLGYVGESVKHFNP
EFVRGCLAVKIHD"
misc_feature 325963..326730
/locus_tag="ECOK1_0292"
/note="Aldo-keto reductases (AKRs) are a superfamily of
soluble NAD(P)(H) oxidoreductases whose chief purpose is
to reduce aldehydes and ketones to primary and secondary
alcohols. AKRs are present in all phyla and are of
importance to both health and industrial...; Region:
Aldo_ket_red; cd06660"
/db_xref="CDD:119408"
misc_feature 325987..326733
/locus_tag="ECOK1_0292"
/note="Aldo/keto reductase family; Region: Aldo_ket_red;
pfam00248"
/db_xref="CDD:201112"
misc_feature order(325996..326004,326074..326076,326089..326091,
326176..326178,326278..326283,326362..326367,
326428..326430,326506..326523,326590..326592,
326635..326646,326659..326661,326668..326673)
/locus_tag="ECOK1_0292"
/note="active site"
/db_xref="CDD:119408"
misc_feature order(326074..326076,326089..326091,326176..326178,
326278..326280)
/locus_tag="ECOK1_0292"
/note="catalytic tetrad [active]"
/db_xref="CDD:119408"
gene complement(326974..327567)
/locus_tag="ECOK1_0293"
/db_xref="GeneID:12688861"
CDS complement(326974..327567)
/locus_tag="ECOK1_0293"
/note="identified by match to protein family HMM PF04224"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099537.1"
/db_xref="GI:386598031"
/db_xref="GeneID:12688861"
/translation="MERYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSIT
PFVANSPLMSFFYEHPEDYKQHLTHEGEYKPEARAWQTANNTYGFSNGLGVVEVIIAL
LVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
LKDTLMLAGAVMIMADSARDILKQRSNESSSTLKTEY"
misc_feature complement(327010..327567)
/locus_tag="ECOK1_0293"
/note="Predicted membrane protein [Function unknown];
Region: COG3059"
/db_xref="CDD:225601"
gene complement(327579..327815)
/locus_tag="ECOK1_0294"
/db_xref="GeneID:12688862"
CDS complement(327579..327815)
/locus_tag="ECOK1_0294"
/note="identified by match to protein family HMM PF07338"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099538.1"
/db_xref="GI:386598032"
/db_xref="GeneID:12688862"
/translation="MFKKSVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLE
NAIADMARKYNASSWKVTSMRIDNNSTATAVLYK"
misc_feature complement(327582..327725)
/locus_tag="ECOK1_0294"
/note="Protein of unknown function (DUF1471); Region:
DUF1471; pfam07338"
/db_xref="CDD:203619"
gene complement(327924..329249)
/locus_tag="ECOK1_0295"
/db_xref="GeneID:12688863"
CDS complement(327924..329249)
/locus_tag="ECOK1_0295"
/note="identified by match to protein family HMM PF00070;
match to protein family HMM PF02852; match to protein
family HMM PF07992"
/codon_start=1
/transl_table=11
/product="pyridine nucleotide-disulfide oxidoreductase"
/protein_id="YP_006099539.1"
/db_xref="GI:386598033"
/db_xref="GeneID:12688863"
/translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCI
NIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFI
NNHSLRVHRPGRNLEIHGEKIFINTGAQAVVPPIPGITTTPGVYDSTGLLNLKELPGH
LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIIL
NAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVV
DKQLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGRRSTDDRKNVPYSVFM
TPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRILGA
SLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK"
misc_feature complement(327927..329249)
/locus_tag="ECOK1_0295"
/note="pyridine nucleotide-disulfide oxidoreductase;
Provisional; Region: PRK08010"
/db_xref="CDD:181196"
misc_feature complement(<329148..329243)
/locus_tag="ECOK1_0295"
/note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
NADB_Rossmann; cl09931"
/db_xref="CDD:214164"
misc_feature complement(328545..328739)
/locus_tag="ECOK1_0295"
/note="Pyridine nucleotide-disulphide oxidoreductase;
Region: Pyr_redox; pfam00070"
/db_xref="CDD:200974"
misc_feature complement(327951..328268)
/locus_tag="ECOK1_0295"
/note="Pyridine nucleotide-disulphide oxidoreductase,
dimerisation domain; Region: Pyr_redox_dim; pfam02852"
/db_xref="CDD:202431"
gene 329476..330330
/locus_tag="ECOK1_0296"
/db_xref="GeneID:12688864"
CDS 329476..330330
/locus_tag="ECOK1_0296"
/note="identified by match to protein family HMM PF00165"
/codon_start=1
/transl_table=11
/product="AraC family transcriptional regulator"
/protein_id="YP_006099540.1"
/db_xref="GI:386598034"
/db_xref="GeneID:12688864"
/translation="MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHAL
TQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHVDNESTCIVCGTLRLQHSARYFL
TSLPETLFVAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
IAQVNTEKNILSLLLHPRLGAVIQQMMEMPGHAWTVESLASIAHMSRASFAQLFRDVS
GTTPLAVLTKLRLQIAAQMFSREMLPVVVIAESVGYASESSFHKAFVREFGCTPGEYR
ERVRQLAP"
misc_feature 329479..329961
/locus_tag="ECOK1_0296"
/note="Cupin; Region: Cupin_6; pfam12852"
/db_xref="CDD:205108"
misc_feature 330055..330303
/locus_tag="ECOK1_0296"
/note="helix_turn_helix, arabinose operon control protein;
Region: HTH_ARAC; smart00342"
/db_xref="CDD:197666"
misc_feature <330217..330303
/locus_tag="ECOK1_0296"
/note="Bacterial regulatory helix-turn-helix proteins,
AraC family; Region: HTH_AraC; pfam00165"
/db_xref="CDD:143933"
gene 330857..331576
/locus_tag="ECOK1_0297"
/db_xref="GeneID:12688865"
CDS 330857..331576
/locus_tag="ECOK1_0297"
/note="identified by match to protein family HMM PF02754"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099541.1"
/db_xref="GI:386598035"
/db_xref="GeneID:12688865"
/translation="MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQ
PAINSGYIKEAIPGMKNLIAALEDNDDPIISPAGSCTYAVKSYPTYLADEPEWASRAE
KVAARMQDLTSFIVNTLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVAHLMEVRPEYLIGADVSCLLNISG
RLQREGQKVKVMHIAEVLMSR"
misc_feature <330857..331573
/locus_tag="ECOK1_0297"
/note="Fe-S oxidoreductase [Energy production and
conversion]; Region: GlpC; COG0247"
/db_xref="CDD:223325"
misc_feature 330863..331111
/locus_tag="ECOK1_0297"
/note="Cysteine-rich domain; Region: CCG; pfam02754"
/db_xref="CDD:202376"
misc_feature 331250..331507
/locus_tag="ECOK1_0297"
/note="Cysteine-rich domain; Region: CCG; pfam02754"
/db_xref="CDD:202376"
gene 331587..333014
/locus_tag="ECOK1_0298"
/db_xref="GeneID:12688866"
CDS 331587..333014
/locus_tag="ECOK1_0298"
/note="identified by match to protein family HMM PF02589;
match to protein family HMM TIGR00273"
/codon_start=1
/transl_table=11
/product="iron-sulfur cluster binding protein"
/protein_id="YP_006099542.1"
/db_xref="GI:386598036"
/db_xref="GeneID:12688866"
/translation="MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDE
LGHWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQNGGHVYFAKTKEDATRYILQVAQ
RKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQDPPSHVVVPAIHK
DRHQIRRVLHEHLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCL
VTNEGNARMCTTLPKTHIAVMGMERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTG
PREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMNTCPAYRHIGGHGYG
SIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDSVCPVRIPLSKLILRHRRVMAEK
GITAKAEQRAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEAR
DLPEADGESFRSWFKKHQAQEKKNG"
misc_feature 331638..332945
/locus_tag="ECOK1_0298"
/note="iron-sulfur cluster-binding protein; Region:
TIGR00273"
/db_xref="CDD:129374"
misc_feature 331800..332468
/locus_tag="ECOK1_0298"
/note="Uncharacterized ACR, YkgG family COG1556; Region:
DUF162; pfam02589"
/db_xref="CDD:202298"
misc_feature <332499..>332765
/locus_tag="ECOK1_0298"
/note="The HCP family of iron-sulfur proteins includes
hybrid cluster protein (HCP), acetyl-CoA synthase (ACS),
and carbon monoxide dehydrogenase (CODH), all of which
contain [Fe4-S4] metal clusters at their active sites.
These proteins have a conserved...; Region: HCP_like;
cl14655"
/db_xref="CDD:187409"
misc_feature 332739..332999
/locus_tag="ECOK1_0298"
/note="Domain of unknown function (DUF3390); Region:
DUF3390; pfam11870"
/db_xref="CDD:152306"
gene 333007..333702
/locus_tag="ECOK1_0299"
/db_xref="GeneID:12688867"
CDS 333007..333702
/locus_tag="ECOK1_0299"
/note="identified by similarity to GB:AAN78905.1; match to
protein family HMM PF02589"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099543.1"
/db_xref="GI:386598037"
/db_xref="GeneID:12688867"
/translation="MDNRSKFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTQLTQQ
QRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKELGDQSVVISGDTRLEELGISER
LQQECNAVVWDPAKGIENISQAEQAKVGVVYAEYGLTESGGVVLFSAAGRGRSLSLLP
ESSLFILRKSTILPRVAQLAEKLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVH
GPVKAVYLIIEDC"
misc_feature 333007..333699
/locus_tag="ECOK1_0299"
/note="Uncharacterized conserved protein [Function
unknown]; Region: COG1556"
/db_xref="CDD:31745"
gene complement(333945..334613)
/locus_tag="ECOK1_0300"
/db_xref="GeneID:12688868"
CDS complement(333945..334613)
/locus_tag="ECOK1_0300"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099544.1"
/db_xref="GI:386598038"
/db_xref="GeneID:12688868"
/translation="MNEQIKQDIDLIEILFYLKKKIRVILFIIAICMVMVLLFLYINK
DNIKVTYSLKINQTTPGILVSCDSNNNFACQTTMTEDVIQRITTFFQTSPDVKNREIK
LEWSGNKRDLPTAEAEISRVQASIIKWYASEYHNGRQVLDEIQTPSAINSELYTKMIY
LTRNWSLYPNGDGCVTISSPEIKNKYPAAICLALGFFLSIVISVMFCLVKKMVDEYQQ
NSGQ"
misc_feature complement(333978..334211)
/locus_tag="ECOK1_0300"
/note="G-rich domain on putative tyrosine kinase; Region:
GNVR; pfam13807"
/db_xref="CDD:205980"
gene complement(334797..337094)
/locus_tag="ECOK1_0301"
/db_xref="GeneID:12688869"
CDS complement(334797..337094)
/locus_tag="ECOK1_0301"
/note="identified by match to protein family HMM PF03797;
match to protein family HMM TIGR01414"
/codon_start=1
/transl_table=11
/product="putative outer membrane autotransporter"
/protein_id="YP_006099545.1"
/db_xref="GI:386598039"
/db_xref="GeneID:12688869"
/translation="MKNSKAFYRSALATAIVMALSAPAFATDSTVSTDPVTLNTEKTT
LDQDVVINGDNKITAVTIETSDSDKDLNVTFGGHDITAASTVNQDFVEGVKVSGNKNV
VINATDSTITAQGEGTYVRTAMVIDSTGDVVVNGGNFVAKNEKGSATGISLEATTGNN
LTLNGTTINAQGNKSYSNGSTAIFAQKGNLLQGFDGDATDNITLADSNIINGGIETIV
TAGNKTGIHTVNLNIKDGSVIGAANNKQTIYASASAQGAGSATQNLNLSVADSTIYSD
VLALSESENSASTTTNVNMNVARSYWEGNAYTFNSGDKAGSDLDINLSDSSVWKGKVS
GAGDASVSLQNGSVWNVTGSSTVDALAVKDSTVNITKATVNTGTFASQNGTLIVDASS
ENTLDISGKASGDLRVYSAGSLDLINEQTAFISTGKDSTLKATGTTEGGLYQYDLTQG
ADGNFYFVKNTHKASNASSVIQAMAAAPANVANLQADTLSARQDAVRLSENDKGGVWI
QYFGGKQKHTTAGNASYDLDVNGVMLGGDTRFMTEDGSWLAGVAMSSAKGDMTTMQSK
GDTEGYSFHAYLSRQYNNGIFIDTAAQFGHYSNTADVRLMNGGGTIKADFNTNGFGAM
VKGGYTWKDGNGLFIQPYAKLSALTLEGVDYQLNGVDVHSDSYNSVLGEAGTRVGYDF
AVGNATVKPYLNLAALNEFSDGNKVRLGDESVNASIDGAAFRVGAGVQADITKNMGAY
ASLDYTKGDDIENPLQGVVGINVTW"
misc_feature complement(335712..>336173)
/locus_tag="ECOK1_0301"
/note="Pertactin-like passenger domains (virulence
factors) of autotransporter proteins of the type V
secretion system. Autotransporters are proteins used by
Gram-negative bacteria to transport proteins across their
outer membranes. The C-terminal (beta) domain...; Region:
PL_Passenger_AT; cl00185"
/db_xref="CDD:199259"
misc_feature complement(334800..336002)
/locus_tag="ECOK1_0301"
/note="outer membrane autotransporter barrel domain;
Region: autotrans_barl; TIGR01414"
/db_xref="CDD:162346"
misc_feature complement(334845..335597)
/locus_tag="ECOK1_0301"
/note="Autotransporter beta-domain; Region:
Autotransporter; pfam03797"
/db_xref="CDD:202770"
gene complement(337136..337897)
/locus_tag="ECOK1_0302"
/db_xref="GeneID:12688870"
CDS complement(337136..337897)
/locus_tag="ECOK1_0302"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099546.1"
/db_xref="GI:386598040"
/db_xref="GeneID:12688870"
/translation="MRFVLFCPSGIVPAQFAALSTGSVGNVTCIRTEEELRNKLRHRP
QSVVISAGRPAECAEMWFRFYRDHSFVVVLCVAPFFLPPDVSISGVLKNLRLLKPGMS
VERVISIANASGGFSGLKHAEILPVMDSYSVFMKEVNNRTKTIVMSERFPEKQKKVLS
LLLAGHSWEYSAQFLKTGIRQIWLAEQSLKKRWGIPDSMSLREALLLSSNNFHGDGNA
LETTNAMTLRENGNTNRYSVVVNAGTQALSLHKYK"
gene complement(338051..338845)
/locus_tag="ECOK1_0303"
/db_xref="GeneID:12688871"
CDS complement(338051..338845)
/locus_tag="ECOK1_0303"
/note="identified by match to protein family HMM PF00196"
/codon_start=1
/transl_table=11
/product="HTH luxR-type DNA-binding domain protein"
/protein_id="YP_006099547.1"
/db_xref="GI:386598041"
/db_xref="GeneID:12688871"
/translation="MKKPLVIISACQFTRLALESLIPTDRYIVRVYSNVTTEVEFVLK
TSCGYLLADIPSLPSGELVLLACLARLRSDAGQWQVCLTGDSDWFDNAPAASLYNGFP
RIGTMLTASRYQNQIIRWLLRPLPGDMSDFWLLTARELSVLKILMQGMSFSEIARYEQ
RSSKTLHAIATRALMKLGLGTLSDFRLLYTGCGDSRVKRNIRLHAKYIGQHSAHRLTQ
YVQNMVSGILYPEKVAVGESINSDAISGKVLSGQRKNISKKRPGLL"
misc_feature complement(338309..>338446)
/locus_tag="ECOK1_0303"
/note="Response regulator containing a CheY-like receiver
domain and an HTH DNA-binding domain [Signal transduction
mechanisms / Transcription]; Region: CitB; COG2197"
/db_xref="CDD:225107"
misc_feature complement(338291..338443)
/locus_tag="ECOK1_0303"
/note="C-terminal DNA-binding domain of LuxR-like
proteins. This domain contains a helix-turn-helix motif
and binds DNA. Proteins belonging to this group are
response regulators; some act as transcriptional
activators, others as transcriptional repressors. Many...;
Region: LuxR_C_like; cd06170"
/db_xref="CDD:99777"
misc_feature complement(order(338300..338302,338333..338347,
338351..338356,338360..338365,338387..338395,
338432..338440))
/locus_tag="ECOK1_0303"
/note="DNA binding residues [nucleotide binding]"
/db_xref="CDD:99777"
misc_feature complement(order(338294..338302,338393..338395,
338399..338401,338405..338407))
/locus_tag="ECOK1_0303"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:99777"
gene complement(339175..339738)
/locus_tag="ECOK1_0304"
/db_xref="GeneID:12688872"
CDS complement(339175..339738)
/locus_tag="ECOK1_0304"
/note="identified by match to protein family HMM PF00589"
/codon_start=1
/transl_table=11
/product="site-specific recombinase, phage integrase
family"
/protein_id="YP_006099548.1"
/db_xref="GI:386598042"
/db_xref="GeneID:12688872"
/translation="MTRKYLTQDEVYRLMDAAQSMSFPERNRCLIMMAFIHGFRASEL
LDLRLSDIDASGKQLNIRRIKNGFSTTHPLLPDEYNLIKLWLKQRKLIENGVEGDWLF
LSRKRRPISRQHFFSIIREAGKRAGLAVKAHPHMLRHACGFALADNGVDTRLLQDYLG
HRNIQHTVRYTASNAARFKGVWKKKPR"
misc_feature complement(339193..339732)
/locus_tag="ECOK1_0304"
/note="DNA breaking-rejoining enzymes, C-terminal
catalytic domain. The DNA breaking-rejoining enzyme
superfamily includes type IB topoisomerases and tyrosine
recombinases that share the same fold in their catalytic
domain containing six conserved active site...; Region:
DNA_BRE_C; cl00213"
/db_xref="CDD:241691"
misc_feature complement(order(339229..339231,339334..339342,
339544..339546,339616..339621))
/locus_tag="ECOK1_0304"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:238231"
misc_feature complement(order(339229..339231,339256..339258,
339325..339327,339334..339336,339544..339546,
339619..339621))
/locus_tag="ECOK1_0304"
/note="Int/Topo IB signature motif; other site"
/db_xref="CDD:238231"
misc_feature complement(order(339229..339231,339256..339258,
339325..339327,339334..339336,339619..339621))
/locus_tag="ECOK1_0304"
/note="active site"
/db_xref="CDD:238231"
gene complement(340810..342498)
/gene="betA"
/locus_tag="ECOK1_0305"
/db_xref="GeneID:12688873"
CDS complement(340810..342498)
/gene="betA"
/locus_tag="ECOK1_0305"
/EC_number="1.1.99.1"
/note="identified by similarity to SP:P17444; match to
protein family HMM PF00732; match to protein family HMM
PF05199; match to protein family HMM TIGR01810"
/codon_start=1
/transl_table=11
/product="choline dehydrogenase"
/protein_id="YP_006099549.1"
/db_xref="GI:386598043"
/db_xref="GeneID:12688873"
/translation="MQFDYIIIGAGSAGNVLATRLTEDPNTTVLLLEAGGPDYRFDFR
TQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAL
DLDNWAQEPGLENWSYLDCLPYYRKAETRDVGENDYHGGDGPVSVTTSKPGVNPLFEA
MIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPHGRRASTARGYLDQAKSRPNLTIRT
HAMTDHIFFDGKRAVGVEWLEGDSTIPTRAAANKEVLLCAGAIASPQILQRSGVGNAE
LLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGG
TGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP
SRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISP
GVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMAVVDAEGRVHGLEGLRVVDASIM
PQIITGNLNATTIMIGEKMADMIRGKDALPRSTARYFVANGMPVRAKKMSRDVN"
misc_feature complement(340828..342498)
/gene="betA"
/locus_tag="ECOK1_0305"
/note="choline dehydrogenase; Validated; Region: PRK02106"
/db_xref="CDD:179368"
misc_feature complement(340921..341322)
/gene="betA"
/locus_tag="ECOK1_0305"
/note="GMC oxidoreductase; Region: GMC_oxred_C; pfam05199"
/db_xref="CDD:203202"
gene complement(342512..343984)
/gene="betB"
/locus_tag="ECOK1_0306"
/db_xref="GeneID:12688874"
CDS complement(342512..343984)
/gene="betB"
/locus_tag="ECOK1_0306"
/EC_number="1.2.1.8"
/note="identified by similarity to SP:P17445; match to
protein family HMM PF00171; match to protein family HMM
TIGR01804"
/codon_start=1
/transl_table=11
/product="betaine aldehyde dehydrogenase"
/protein_id="YP_006099550.1"
/db_xref="GI:386598044"
/db_xref="GeneID:12688874"
/translation="MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGRE
DVDRAVKSAQQGQKIWAAMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETS
TVDIVTGADVLEYYAGLIPALEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIAL
WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTD
HPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADITMM
ANFFSSGQVCTNGTRVFVPTKCKAAFEQKILARVERIRAGDVFDPQTNFGPLVSFPHR
DNVLRYIAKGIEEGARVLCGGDVLKGDSFDNGAWVAPTVFTDCSDDMTIVREEIFGPV
MSILTYESEDEVIRRANDTDYGLAAGIVTADLNLAHRVIHQLEAGICWINTWGESPAE
MPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF"
misc_feature complement(342515..343984)
/gene="betB"
/locus_tag="ECOK1_0306"
/note="betaine aldehyde dehydrogenase; Provisional;
Region: PRK13252"
/db_xref="CDD:183918"
misc_feature complement(342536..343909)
/gene="betB"
/locus_tag="ECOK1_0306"
/note="NAD+-dependent 4-trimethylaminobutyraldehyde
dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH;
cd07090"
/db_xref="CDD:143409"
misc_feature complement(order(342536..342541,342545..342562,
342596..342598,342602..342604,342611..342613,
342617..342619,342629..342631,342635..342637,
342659..342664,342668..342679,342683..342685,
342692..342694,342698..342703,342710..342721,
343013..343015,343058..343060,343157..343162,
343169..343171,343178..343180,343244..343246,
343280..343282,343562..343570,343574..343576,
343598..343612,343631..343633,343643..343645,
343745..343747,343754..343756,343766..343768,
343775..343777,343787..343789,343793..343795))
/gene="betB"
/locus_tag="ECOK1_0306"
/note="tetrameric interface [polypeptide binding]; other
site"
/db_xref="CDD:143409"
misc_feature complement(order(342626..342628,342818..342820,
342824..342826,343127..343129,343223..343231,
343286..343288,343295..343300,343304..343306,
343358..343360,343457..343459,343526..343531,
343535..343540))
/gene="betB"
/locus_tag="ECOK1_0306"
/note="NAD binding site [chemical binding]; other site"
/db_xref="CDD:143409"
misc_feature complement(order(343127..343129,343136..343138,
343229..343231,343526..343528))
/gene="betB"
/locus_tag="ECOK1_0306"
/note="catalytic residues [active]"
/db_xref="CDD:143409"
gene complement(343998..344585)
/gene="betI"
/locus_tag="ECOK1_0307"
/db_xref="GeneID:12688875"
CDS complement(343998..344585)
/gene="betI"
/locus_tag="ECOK1_0307"
/note="identified by similarity to SP:P17446; match to
protein family HMM PF00440; match to protein family HMM
TIGR03384"
/codon_start=1
/transl_table=11
/product="transcriptional repressor BetI"
/protein_id="YP_006099551.1"
/db_xref="GI:386598045"
/db_xref="GeneID:12688875"
/translation="MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTG
IISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAELRLQAIVGGNFDETQVS
SAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPRQQAQEAGYGLAAL
IDGLWLRAALSGKALDKPLAHSLTRHFITQHLPTD"
misc_feature complement(344004..344585)
/gene="betI"
/locus_tag="ECOK1_0307"
/note="transcriptional regulator BetI; Validated; Region:
PRK00767"
/db_xref="CDD:179115"
misc_feature complement(344409..344546)
/gene="betI"
/locus_tag="ECOK1_0307"
/note="Bacterial regulatory proteins, tetR family; Region:
TetR_N; pfam00440"
/db_xref="CDD:201228"
misc_feature complement(344010..344342)
/gene="betI"
/locus_tag="ECOK1_0307"
/note="Bacterial transcriptional repressor; Region:
TetR_C_6; pfam13977"
/db_xref="CDD:206147"
gene 344714..346747
/gene="betT"
/locus_tag="ECOK1_0308"
/db_xref="GeneID:12688876"
CDS 344714..346747
/gene="betT"
/locus_tag="ECOK1_0308"
/note="identified by match to protein family HMM PF02028;
match to protein family HMM TIGR00842"
/codon_start=1
/transl_table=11
/product="transporter, betaine/carnitine/choline
transporter (BCCT) family"
/protein_id="YP_006099552.1"
/db_xref="GI:386598046"
/db_xref="GeneID:12688876"
/translation="MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIG
RTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFA
AGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLN
YGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVL
FMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFV
GLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHP
ERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWL
RVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRE
SANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRG
AYVELKNLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYR
LETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDS"
misc_feature 344714..346744
/gene="betT"
/locus_tag="ECOK1_0308"
/note="choline transport protein BetT; Provisional;
Region: PRK09928"
/db_xref="CDD:182150"
gene 347625..348713
/locus_tag="ECOK1_0309"
/db_xref="GeneID:12688877"
CDS 347625..348713
/locus_tag="ECOK1_0309"
/note="identified by match to protein family HMM PF00196;
match to protein family HMM PF00563"
/codon_start=1
/transl_table=11
/product="LuxR-family transcriptional regulator/cyclic
diguanylate phosphodiesterase (EAL) domain protein"
/protein_id="YP_006099553.1"
/db_xref="GI:386598047"
/db_xref="GeneID:12688877"
/translation="MNSCDFRVFLQEFGTTVHLSLPGSVSEKERLLLKLLMQGMSVTE
ISQYRNRSAKTISHQKKQLFEKLGIQSDITFWRDIFFQYNPEIISATGNNSHKYINDN
HYHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGMIPPDQFI
PLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNL
VKKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQA
FPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKG
VHFLQGYLYSPPVPGNKFISEWVMKAGG"
misc_feature 347700..347864
/locus_tag="ECOK1_0309"
/note="C-terminal DNA-binding domain of LuxR-like
proteins. This domain contains a helix-turn-helix motif
and binds DNA. Proteins belonging to this group are
response regulators; some act as transcriptional
activators, others as transcriptional repressors. Many...;
Region: LuxR_C_like; cd06170"
/db_xref="CDD:99777"
misc_feature order(347700..347708,347745..347753,347775..347780,
347784..347789,347793..347807,347838..347840)
/locus_tag="ECOK1_0309"
/note="DNA binding residues [nucleotide binding]"
/db_xref="CDD:99777"
misc_feature order(347733..347735,347739..347741,347745..347747,
347838..347846,347853..347855,347862..347864)
/locus_tag="ECOK1_0309"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:99777"
misc_feature 347955..348668
/locus_tag="ECOK1_0309"
/note="EAL domain. This domain is found in diverse
bacterial signaling proteins. It is called EAL after its
conserved residues and is also known as domain of unknown
function 2 (DUF2). The EAL domain has been shown to
stimulate degradation of a second...; Region: EAL;
cd01948"
/db_xref="CDD:30163"
gene complement(348755..349687)
/locus_tag="ECOK1_0310"
/note="transcriptional regulator, LysR family; this gene
contains a frame shift which may be the result of a
sequencing error; identified by match to protein family
HMM PF00126; match to protein family HMM PF03466"
/pseudo
/db_xref="GeneID:12688878"
gene complement(349779..350276)
/locus_tag="ECOK1_0311"
/db_xref="GeneID:12688879"
CDS complement(349779..350276)
/locus_tag="ECOK1_0311"
/note="identified by similarity to GB:AAN78918.1; match to
protein family HMM PF06496"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099554.1"
/db_xref="GI:386598048"
/db_xref="GeneID:12688879"
/translation="MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCS
FYAAGGGKSGFIKSLAVNYSGMVWAFFAALAAGWLAPVSGLSAFWASVITTVPFSAVV
VWQGRFWLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGIISEYGGQKLSEATT
KSDGY"
misc_feature complement(349806..350252)
/locus_tag="ECOK1_0311"
/note="Protein of unknown function (DUF1097); Region:
DUF1097; pfam06496"
/db_xref="CDD:219062"
gene 350534..351139
/locus_tag="ECOK1_0312"
/db_xref="GeneID:12688880"
CDS 350534..351139
/locus_tag="ECOK1_0312"
/note="identified by match to protein family HMM PF00023"
/codon_start=1
/transl_table=11
/product="ankyrin"
/protein_id="YP_006099555.1"
/db_xref="GI:386598049"
/db_xref="GeneID:12688880"
/translation="MTIKNLPADYLLAAQQGDIDKVKICLALGVDINTCDRQGKTAIT
LASLYQQYACVQALIDAGANINKQDHTCLNPFLISCLNDDLTLLRIILPAKPDLNCVT
RFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA"
misc_feature 350567..350830
/locus_tag="ECOK1_0312"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 350645..350743
/locus_tag="ECOK1_0312"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cl02529"
/db_xref="CDD:207631"
misc_feature 350729..351124
/locus_tag="ECOK1_0312"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 350759..351055
/locus_tag="ECOK1_0312"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
gene 351179..352042
/locus_tag="ECOK1_0313"
/db_xref="GeneID:12688881"
CDS 351179..352042
/locus_tag="ECOK1_0313"
/note="identified by similarity to GB:AAZ87092.1"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099556.1"
/db_xref="GI:386598050"
/db_xref="GeneID:12688881"
/translation="MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
YDNAPNSCRLALTHFNGLFRHGDKVQFDDQGITVGQHLHIEMSHCQRWLSPTLQMTAL
NFHLIAWQQWHDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVNDKQNI
AVAVASMMGLGIGLTPSADDYLTGLALILFLPGHPAEKYKEEFYLGLQRGRNNTTLLS
AITLEAALQQRCRENIHRFIHNIIYDIPGNATQAIEKIKHIGSSSGCDMLYGMADGCA
LSQTYGGNYVS"
misc_feature 351677..352009
/locus_tag="ECOK1_0313"
/note="Protein of unknown function (DUF2877); Region:
DUF2877; pfam11392"
/db_xref="CDD:151832"
gene 352032..353579
/locus_tag="ECOK1_0314"
/db_xref="GeneID:12688882"
CDS 352032..353579
/locus_tag="ECOK1_0314"
/note="identified by match to protein family HMM PF06263"
/codon_start=1
/transl_table=11
/product="bacterial FdrA protein"
/protein_id="YP_006099557.1"
/db_xref="GI:386598051"
/db_xref="GeneID:12688882"
/translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
GVLKNLGLLTPELEQAKNGDLMIVINGKSGVDNEQLLAEIEELFNTKAQSGSHEARYA
TIASAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
LIGTGGRDLSEKIGGLMMLDAIGMLENDPQTEIIVLISKPPAPAVARKVLERARACRK
PVVACFLGRGETPVDEQGLQFARGSKEAALKAVMLSGVKQEHLDLHTLNQPLIADVRA
RLQPQQKYIRGLFCGGTLCDETLFAVMEKHGDVYSNIQPDPEFRLQDINRSIKHTFLD
FGDDDFTNGKPHPMIDPTNRISRVIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIEAI
KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
ICKGEEA"
misc_feature 352086..353147
/locus_tag="ECOK1_0314"
/note="Succinyl-CoA synthetase, alpha subunit [Energy
production and conversion]; Region: SucD; COG0074"
/db_xref="CDD:30423"
misc_feature 352590..352883
/locus_tag="ECOK1_0314"
/note="CoA binding domain; Region: CoA_binding; pfam02629"
/db_xref="CDD:202320"
misc_feature 353067..353546
/locus_tag="ECOK1_0314"
/note="CoA-ligase; Region: Ligase_CoA; pfam00549"
/db_xref="CDD:201299"
gene 353579..354997
/locus_tag="ECOK1_0315"
/db_xref="GeneID:12688883"
CDS 353579..354997
/locus_tag="ECOK1_0315"
/note="identified by match to protein family HMM PF06545"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099558.1"
/db_xref="GI:386598052"
/db_xref="GeneID:12688883"
/translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQLDWTPPGQGNM
QVVQALDNIADSPLADKIASANQQALERIIQSHPVLIGFDQAINVVPGMTAKTILHAG
PPVTWEKMCGAMKGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGV
TSASMFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPMLRDA
MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVEQQREVFEF
VASCDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
QMREITLGENPNVTIPLLGFMGVPSAIDITRVGSSGILPVINTAIAHKDAGIGMIGAG
IVHPPFACFEKAIFGWCERYGV"
misc_feature 354005..354652
/locus_tag="ECOK1_0315"
/note="Protein of unknown function (DUF1116); Region:
DUF1116; pfam06545"
/db_xref="CDD:148259"
gene 355151..356101
/locus_tag="ECOK1_0316"
/db_xref="GeneID:12688884"
CDS 355151..356101
/locus_tag="ECOK1_0316"
/note="identified by match to protein family HMM PF00696"
/codon_start=1
/transl_table=11
/product="putative carbamate kinase"
/protein_id="YP_006099559.1"
/db_xref="GI:386598053"
/db_xref="GeneID:12688884"
/translation="MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASD
YDIVLTHGNGPQVGLDLRRAEIAHEREGLPLTPLANCVADTQGGIGYLIQQALNNRLA
RHGEKKAVTVVTQVEVDKNDPGFAHPIKPIGAFFSESQRDELQKANPDWRFVEDAGRG
YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTDAGDYQSVDAVIDKDL
STALLAREIHADILVITTGVEKVCIHFGKPQQQALDRVDIATMTRYMQEGHFPPGSML
PKIIASLTFLEQGGKEVIITTPECLPAALRGETGTHIIKT"
misc_feature 355151..356095
/locus_tag="ECOK1_0316"
/note="carbamate kinase-like carbamoyl phosphate
synthetase; Reviewed; Region: PRK12454"
/db_xref="CDD:183535"
misc_feature 355160..356092
/locus_tag="ECOK1_0316"
/note="AAK_CK: Carbamate kinase (CK) catalyzes both the
ATP-phosphorylation of carbamate and carbamoyl phosphate
(CP) utilization with the production of ATP from ADP and
CP. Both CK (this CD) and nonhomologous CP synthetase
synthesize carbamoyl phosphate, an...; Region: AAK_CK;
cd04235"
/db_xref="CDD:58601"
misc_feature order(355172..355174,355178..355183,355304..355312,
355538..355540,355793..355801)
/locus_tag="ECOK1_0316"
/note="putative substrate binding site [chemical binding];
other site"
/db_xref="CDD:58601"
misc_feature order(355181..355183,355856..355861,355874..355876,
355883..355885,355958..355960,355970..355975,
355982..355984)
/locus_tag="ECOK1_0316"
/note="nucleotide binding site [chemical binding]; other
site"
/db_xref="CDD:58601"
misc_feature order(355181..355183,355856..355861,355874..355876,
355883..355885,355958..355960,355970..355975,
355982..355984)
/locus_tag="ECOK1_0316"
/note="nucleotide binding site [chemical binding]; other
site"
/db_xref="CDD:58601"
misc_feature order(355334..355336,355376..355378,355385..355390,
355397..355399,355409..355414,355421..355423,
355430..355435,355445..355447,355481..355489,
355493..355495,355673..355675,355682..355684,
355769..355771,355775..355777)
/locus_tag="ECOK1_0316"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:58601"
gene 356249..357493
/locus_tag="ECOK1_0317"
/db_xref="GeneID:12688885"
CDS 356249..357493
/locus_tag="ECOK1_0317"
/note="identified by match to protein family HMM PF07969"
/codon_start=1
/transl_table=11
/product="amidohydrolase family protein"
/protein_id="YP_006099560.1"
/db_xref="GI:386598054"
/db_xref="GeneID:12688885"
/translation="MKITDPYYYLDNVLLETGFDYENGVAVQTRTARQTVEIQNGKIV
ALRENKQHPDATLPHYDAGGKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMI
KLEQKMLPELQPYTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARR
QAGFECEIVAFPQHGLLLSKSEPLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQI
ALDYDKGVDIHLHETTPAGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDE
LAHRMAAQQISIASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKA
NLYAQLYIRPNEQNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAV
ARISPRTATFHKGQLVWGSVAG"
misc_feature 356255..357490
/locus_tag="ECOK1_0317"
/note="putative deaminase; Validated; Region: PRK06846"
/db_xref="CDD:180726"
misc_feature 356273..357472
/locus_tag="ECOK1_0317"
/note="Bacterial cytosine deaminase and related
metal-dependent hydrolases. Cytosine deaminases (CDs)
catalyze the deamination of cytosine, producing uracil and
ammonia. They play an important role in pyrimidine
salvage. CDs are present in prokaryotes and fungi; Region:
Bact_CD; cd01293"
/db_xref="CDD:30036"
misc_feature order(356471..356473,356477..356479,356933..356935,
356942..356944,357032..357034,357194..357196)
/locus_tag="ECOK1_0317"
/note="active site"
/db_xref="CDD:30036"
gene 357761..358201
/locus_tag="ECOK1_0318"
/db_xref="GeneID:12688886"
CDS 357761..358201
/locus_tag="ECOK1_0318"
/note="identified by similarity to GB:AAV79770.1; match to
protein family HMM PF04266"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099561.1"
/db_xref="GI:386598055"
/db_xref="GeneID:12688886"
/translation="MFFRNRENILMTIKEKISQKYPHASFCTFGDSAALADHLATLIA
TGVKTASCGSLAGCIEDNAFPMIGEYKIVENSRGEPVCVIRVIGLHLLRFSDVTAELA
RKEGEGDLSLEYWRNEHRRFFQAEGCYSPEMDVIFEEYALIDVV"
misc_feature 357830..358192
/locus_tag="ECOK1_0318"
/note="ASC-1 homology domain, subfamily similar to
Enterococcus faecalis Ef3133. The ASCH domain, a small
beta-barrel domain found in all three kingdoms of life,
resembles the RNA-binding PUA domain and may also interact
with RNA. ASCH has been proposed to...; Region:
ASCH_Ef3133_like; cd06553"
/db_xref="CDD:119345"
gene 358455..359438
/locus_tag="ECOK1_0319"
/db_xref="GeneID:12688887"
CDS 358455..359438
/locus_tag="ECOK1_0319"
/codon_start=1
/transl_table=11
/product="putative ABC transporter periplasmic
substrate-binding protein"
/protein_id="YP_006099562.1"
/db_xref="GI:386598056"
/db_xref="GeneID:12688887"
/translation="MNKRFVINMVSSLLLGAALISAPLQAAEKVVVNISKVDGMPWFN
RMGEGVVEAGKAFGVNASQVGPSSTDAPQQVKIIEDLIARKVNAITIVPNDANVLEPV
FKKARDAGIVVLTNESPGQPSANWDIEIIDNEKFAAEYVEHMAKRMGGKGGYVIYVGS
LTVPQHNLWADLLVKYQKEHYPDMHEVTRRMPVAESVDDSRRTTLDLMKTYPDLKAVV
SFGSNGPIGAGRAVKEKRAKNKVAVYGMMIPSQAASLIKSGDITEGITYDPASAGYAL
AAVASTLLKGEEIKPGLEMQNLGKADVDMDKRIIRFHKVLLVNKDNIDSLY"
misc_feature 358542..359426
/locus_tag="ECOK1_0319"
/note="Periplasmic binding domain of autoinducer-2 (AI-2)
receptor LsrB from Salmonella typhimurium and its close
homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302"
/db_xref="CDD:107297"
misc_feature 358545..359318
/locus_tag="ECOK1_0319"
/note="Periplasmic binding protein domain; Region:
Peripla_BP_4; pfam13407"
/db_xref="CDD:222108"
misc_feature order(358560..358562,358803..358805,358842..358844,
358947..358952,358959..358961,359112..359120,
359253..359255)
/locus_tag="ECOK1_0319"
/note="ligand binding site [chemical binding]; other site"
/db_xref="CDD:107297"
gene 359487..360971
/locus_tag="ECOK1_0320"
/db_xref="GeneID:12688888"
CDS 359487..360971
/locus_tag="ECOK1_0320"
/note="identified by match to protein family HMM PF00005"
/codon_start=1
/transl_table=11
/product="ABC transporter ATP-binding protein"
/protein_id="YP_006099563.1"
/db_xref="GI:386598057"
/db_xref="GeneID:12688888"
/translation="METFLSLRHINKTFHATRALRDVSLDFMSGEVHCLAGQNGCGKS
TLIKIMSGVYRPDEGAEITLGGKNWSKLTPAASVAQGIQVIYQDLSLFPNLSVWENIA
VNHYHHGLFVNRRRLREVAQAAMTSINVTLPLDTLVSELSIARCQLVAICRALAQDAR
LIVMDEPTASLTHQEVQGLLQVVHQLRERGICVVFVSHRLEEVMEVSDRISVLKDGEL
VGTFPAAEMTTKQLGFLMTGQEFEYQVRELWQGKSSTPVLEVRNLSRHGEYLNINLRV
EAGEVVSIVGLLGAGRTELCLSLFGMTRPDAGEILINGQLVTLHSNQDAIRHGIGYVS
EDRMSRGLVMAQSIEDNIISTVFHKVKDRFGFLSEAKVCDLVDRLIKALTIKVSDPHL
PVNTLSGGNAQRVSIAKWLAIGPRLLILDSPTVGVDIANKAGIYGIISDLAAHGIAVL
MICDEIEEAWYQSHRILVMQKGQITHSFLPDSSSQARIAEVVNG"
misc_feature 359487..360968
/locus_tag="ECOK1_0320"
/note="ABC-type sugar transport system, ATPase component
[Carbohydrate transport and metabolism]; Region: MglA;
COG1129"
/db_xref="CDD:31325"
misc_feature 359499..360149
/locus_tag="ECOK1_0320"
/note="First domain of the ATP-binding cassette component
of monosaccharide transport system; Region:
ABC_Carb_Monos_I; cd03216"
/db_xref="CDD:213183"
misc_feature 359595..359618
/locus_tag="ECOK1_0320"
/note="Walker A/P-loop; other site"
/db_xref="CDD:213183"
misc_feature order(359604..359609,359613..359621,359745..359747,
359979..359984,360078..360080)
/locus_tag="ECOK1_0320"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:213183"
misc_feature 359736..359747
/locus_tag="ECOK1_0320"
/note="Q-loop/lid; other site"
/db_xref="CDD:213183"
misc_feature 359907..359936
/locus_tag="ECOK1_0320"
/note="ABC transporter signature motif; other site"
/db_xref="CDD:213183"
misc_feature 359967..359984
/locus_tag="ECOK1_0320"
/note="Walker B; other site"
/db_xref="CDD:213183"
misc_feature 359991..360002
/locus_tag="ECOK1_0320"
/note="D-loop; other site"
/db_xref="CDD:213183"
misc_feature 360066..360086
/locus_tag="ECOK1_0320"
/note="H-loop/switch region; other site"
/db_xref="CDD:213183"
misc_feature 360252..360908
/locus_tag="ECOK1_0320"
/note="Second domain of the ATP-binding cassette component
of monosaccharide transport system; Region:
ABC_Carb_Monos_II; cd03215"
/db_xref="CDD:213182"
gene 360964..361935
/locus_tag="ECOK1_0321"
/db_xref="GeneID:12688889"
CDS 360964..361935
/locus_tag="ECOK1_0321"
/note="identified by match to protein family HMM PF02653"
/codon_start=1
/transl_table=11
/product="ABC transporter permease"
/protein_id="YP_006099564.1"
/db_xref="GI:386598058"
/db_xref="GeneID:12688889"
/translation="MAELKKRHEFWLALLIVVLFVGLAWRSDEFLTFGNLYDLANNYA
MLTILACGLFVVLISGGIDISFPAMTIIAQYGMVLLLQKIGGNFAVAFALAGGIGILL
GLINALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEQGVMLFKYTDA
DGYDYGLGLPLIAMITVVLLTAFIMNFTSVGRKIYALGGNRESASRIGFSVLKLQLFV
YGYMGLMSGAAGVVQSWTVMTVAPDSLLGYELTVLAAVVLGGTSLLGGRGTLTGTLLG
VVLLAVMQNGLNLLGVSSYWQTLITGIIIVASISATAWSQHQNRSLL"
misc_feature 361093..361899
/locus_tag="ECOK1_0321"
/note="Transmembrane subunit (TM) of Escherichia coli AraH
and related proteins. E. coli AraH is the TM of a
Periplasmic Binding Protein (PBP)-dependent ATP-Binding
Cassette (ABC) transporter involved in the uptake of the
monosaccharide arabinose. This group...; Region:
TM_PBP1_transp_AraH_like; cd06579"
/db_xref="CDD:119321"
misc_feature 361099..>361716
/locus_tag="ECOK1_0321"
/note="Branched-chain amino acid transport system /
permease component; Region: BPD_transp_2; pfam02653"
/db_xref="CDD:217165"
misc_feature 361567..361623
/locus_tag="ECOK1_0321"
/note="TM-ABC transporter signature motif; other site"
/db_xref="CDD:119321"
gene 361932..362888
/locus_tag="ECOK1_0322"
/db_xref="GeneID:12688890"
CDS 361932..362888
/locus_tag="ECOK1_0322"
/note="identified by match to protein family HMM PF02653"
/codon_start=1
/transl_table=11
/product="ABC transporter permease"
/protein_id="YP_006099565.1"
/db_xref="GI:386598059"
/db_xref="GeneID:12688890"
/translation="MKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQ
MPVLGILALAMAVTMLCGGINLSIIATANACSLVMAWVATQYPPGIATVVATLLAGAG
AAVIIGLCNGVLIAGIRVSPILATLGMMTLLKGVNILVTGGSAIANYPSWVLWLNHAQ
WFGIPLPMWLFTAVALGLWILLEKTPLGKSIYLIGSNERATLYSGINTRRVLIWVYVI
SALLCAVAAFLMMSKLNSAKASYGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFL
LQIIESGFNILGISPYLTMALWGTLLLCFIQARGMLGLDRVV"
misc_feature 362064..362849
/locus_tag="ECOK1_0322"
/note="Transmembrane subunit (TM) of Escherichia coli AraH
and related proteins. E. coli AraH is the TM of a
Periplasmic Binding Protein (PBP)-dependent ATP-Binding
Cassette (ABC) transporter involved in the uptake of the
monosaccharide arabinose. This group...; Region:
TM_PBP1_transp_AraH_like; cd06579"
/db_xref="CDD:119321"
misc_feature 362526..362582
/locus_tag="ECOK1_0322"
/note="TM-ABC transporter signature motif; other site"
/db_xref="CDD:119321"
gene 362975..364024
/locus_tag="ECOK1_0323"
/db_xref="GeneID:12688891"
CDS 362975..364024
/locus_tag="ECOK1_0323"
/note="identified by match to protein family HMM PF00107;
match to protein family HMM PF08240"
/codon_start=1
/transl_table=11
/product="oxidoreductase, zinc-binding dehydrogenase
family"
/protein_id="YP_006099566.1"
/db_xref="GI:386598060"
/db_xref="GeneID:12688891"
/translation="MKIKAVGAYSAKQPLEPMDITRREPGPHDVKIEIAYCGVCHSDI
HQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDG
LENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
ITTYSPLRHWLAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSESKREAAKALG
ADEVVNSRNADEMVAHVKSFDFILNTVAAPHNLDDFTTLLKRDGTITLVGAPATPHKS
PEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRG
DVKYRFVIDNRTLTD"
misc_feature 362975..364012
/locus_tag="ECOK1_0323"
/note="Zn-dependent alcohol dehydrogenases [General
function prediction only]; Region: AdhP; COG1064"
/db_xref="CDD:31264"
misc_feature 362984..364003
/locus_tag="ECOK1_0323"
/note="Cinnamyl alcohol dehydrogenases (CAD); Region:
CAD1; cd05283"
/db_xref="CDD:176186"
misc_feature order(363092..363100,363107..363109,363446..363448,
363458..363460,363518..363535,363587..363592,
363602..363604,363647..363649,363704..363709,
363713..363715,363773..363778,363848..363856)
/locus_tag="ECOK1_0323"
/note="putative NAD(P) binding site [chemical binding];
other site"
/db_xref="CDD:176186"
misc_feature order(363092..363094,363098..363100,363158..363160,
363236..363238,363446..363448,363854..363856)
/locus_tag="ECOK1_0323"
/note="putative substrate binding site [chemical binding];
other site"
/db_xref="CDD:176186"
misc_feature order(363092..363094,363158..363160,363446..363448)
/locus_tag="ECOK1_0323"
/note="catalytic Zn binding site [ion binding]; other
site"
/db_xref="CDD:176186"
misc_feature order(363251..363253,363260..363262,363269..363271,
363293..363295)
/locus_tag="ECOK1_0323"
/note="structural Zn binding site [ion binding]; other
site"
/db_xref="CDD:176186"
misc_feature order(363290..363292,363467..363469,363479..363481,
363755..363757,363770..363778,363782..363784,
363812..363814,363818..363823,363830..363853)
/locus_tag="ECOK1_0323"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:176186"
gene 364576..364656
/locus_tag="ECOK1_0324"
/pseudo
/db_xref="GeneID:12688892"
tRNA 364576..364656
/locus_tag="ECOK1_0324"
/product="tRNA-OTHER"
/note="tRNA-Pseudo"
/pseudo
/db_xref="GeneID:12688892"
gene complement(364908..365576)
/locus_tag="ECOK1_0325"
/db_xref="GeneID:12688893"
CDS complement(364908..365576)
/locus_tag="ECOK1_0325"
/note="identified by match to protein family HMM PF01810;
match to protein family HMM TIGR00949"
/codon_start=1
/transl_table=11
/product="putative homoserine/threonine efflux protein"
/protein_id="YP_006099567.1"
/db_xref="GI:386598061"
/db_xref="GeneID:12688893"
/translation="MKLLHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQTS
LASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAWC
SMRRQSTPQMSTLQQPISAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTWA
RLMAWAGIVLASIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYEG
VTQR"
misc_feature complement(364935..365483)
/locus_tag="ECOK1_0325"
/note="The Resistance to Homoserine/Threonine (RhtB)
Family protein; Region: 2A76; TIGR00949"
/db_xref="CDD:162127"
STS 365697..366331
/standard_name="D14S163"
/db_xref="UniSTS:148387"
gene 365726..366001
/locus_tag="ECOK1_0326"
/db_xref="GeneID:12688894"
CDS 365726..366001
/locus_tag="ECOK1_0326"
/note="identified by match to protein family HMM PF07338"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099568.1"
/db_xref="GI:386598062"
/db_xref="GeneID:12688894"
/translation="MKIISKMLVGALAFAVTNVYAAELMTKAEFEKVESQYEKIGDIS
TSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK"
misc_feature 365726..365998
/locus_tag="ECOK1_0326"
/note="hypothetical protein; Provisional; Region:
PRK09929"
/db_xref="CDD:182151"
gene complement(366102..367688)
/locus_tag="ECOK1_0327"
/note="propionate catabolism operon regulatory protein
PrpR, authentic frameshift; this gene contains a premature
stop which is not the result of sequencing error"
/pseudo
/db_xref="GeneID:12688895"
gene 367927..368817
/gene="prpB"
/locus_tag="ECOK1_0328"
/db_xref="GeneID:12688896"
CDS 367927..368817
/gene="prpB"
/locus_tag="ECOK1_0328"
/EC_number="4.1.3.30"
/note="identified by match to protein family HMM
TIGR02317"
/codon_start=1
/transl_table=11
/product="methylisocitrate lyase"
/protein_id="YP_006099569.1"
/db_xref="GI:386598063"
/db_xref="GeneID:12688896"
/translation="MSLHSPGKAFRAALSKENPLQIVGTINANHALLAQRAGYQAIYL
SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVK
SMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATP
LFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYES
INYYQYEEKLDDLFARNQAK"
misc_feature 367939..368799
/gene="prpB"
/locus_tag="ECOK1_0328"
/note="PEP phosphonomutase and related enzymes
[Carbohydrate transport and metabolism]; Region: PrpB;
COG2513"
/db_xref="CDD:32583"
misc_feature 367954..368679
/gene="prpB"
/locus_tag="ECOK1_0328"
/note="Members of the ICL/PEPM enzyme family catalyze
either P-C or C-C bond formation/cleavage. Known members
are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate
hydrolase (PPH), carboxyPEP mutase (CPEP mutase),
oxaloacetate hydrolase (OAH), isocitrate...; Region:
ICL_PEPM; cd00377"
/db_xref="CDD:119340"
misc_feature order(367960..367962,367981..367983,367987..367998,
368002..368016,368020..368025,368032..368034,
368038..368046,368065..368067,368077..368082,
368089..368091,368095..368097,368104..368115,
368119..368124,368131..368136,368140..368145,
368152..368157,368197..368199,368218..368223,
368233..368235,368242..368244,368329..368334,
368341..368343,368350..368355,368362..368364,
368650..368658,368662..368670,368674..368679)
/gene="prpB"
/locus_tag="ECOK1_0328"
/note="tetramer interface [polypeptide binding]; other
site"
/db_xref="CDD:119340"
misc_feature order(368053..368055,368059..368067,368098..368100,
368179..368181,368185..368187,368269..368271,
368398..368400,368488..368490,368554..368556,
368560..368562,368632..368634)
/gene="prpB"
/locus_tag="ECOK1_0328"
/note="active site"
/db_xref="CDD:119340"
misc_feature order(368098..368100,368179..368181,368185..368187,
368269..368271)
/gene="prpB"
/locus_tag="ECOK1_0328"
/note="Mg2+/Mn2+ binding site [ion binding]; other site"
/db_xref="CDD:119340"
gene 368862..370031
/gene="prpC"
/locus_tag="ECOK1_0329"
/db_xref="GeneID:12688897"
CDS 368862..370031
/gene="prpC"
/locus_tag="ECOK1_0329"
/EC_number="2.3.3.5"
/note="identified by similarity to SP:P31660; match to
protein family HMM PF00285; match to protein family HMM
TIGR01800"
/codon_start=1
/transl_table=11
/product="2-methylcitrate synthase"
/protein_id="YP_006099570.1"
/db_xref="GI:386598064"
/db_xref="GeneID:12688897"
/translation="MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
RGYDILDLAAHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPA
ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
QPETDDDSIGGHFLHLLHGEKPSPSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
MYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
YTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNM
MGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRQFVALDKRQ"
misc_feature 368889..370025
/gene="prpC"
/locus_tag="ECOK1_0329"
/note="Citrate synthase [Energy production and
conversion]; Region: GltA; COG0372"
/db_xref="CDD:30721"
misc_feature 368919..370016
/gene="prpC"
/locus_tag="ECOK1_0329"
/note="Subgroup of Escherichia coli (Ec) 2-methylcitrate
synthase (2MCS)_like. 2MCS catalyzes the condensation of
propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form
2-methylcitrate and coenzyme A (CoA) during propionate
metabolism. Citrate synthase (CS)...; Region:
Ec2MCS_like_1; cd06117"
/db_xref="CDD:99870"
misc_feature order(368919..368927,368934..368948,369132..369137,
369144..369149,369171..369173,369183..369185,
369195..369197,369204..369206,369348..369350,
369459..369473,369480..369485,369495..369497,
369504..369515,369522..369524,369543..369548,
369552..369563,369684..369686,369957..369989)
/gene="prpC"
/locus_tag="ECOK1_0329"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:99870"
misc_feature order(368928..368930,369459..369461,369468..369470,
369561..369569,369573..369575,369582..369584,
369663..369686,369693..369695,369708..369710,
369813..369815,369819..369821,369828..369830,
369834..369836,369897..369899,369909..369911,
369957..369959,369966..369968)
/gene="prpC"
/locus_tag="ECOK1_0329"
/note="active site"
/db_xref="CDD:99870"
misc_feature order(368928..368930,369459..369461,369468..369470,
369561..369566,369663..369668,369672..369686,
369708..369710,369828..369830,369909..369911)
/gene="prpC"
/locus_tag="ECOK1_0329"
/note="citrylCoA binding site [chemical binding]; other
site"
/db_xref="CDD:99870"
misc_feature order(369459..369461,369468..369470,369564..369569,
369681..369683,369708..369710,369834..369836,
369897..369899,369909..369911,369966..369968)
/gene="prpC"
/locus_tag="ECOK1_0329"
/note="oxalacetate/citrate binding site [chemical
binding]; other site"
/db_xref="CDD:99870"
misc_feature order(369561..369566,369573..369575,369582..369584,
369663..369680,369684..369686,369693..369695,
369813..369815,369819..369821,369828..369830,
369834..369836,369957..369959)
/gene="prpC"
/locus_tag="ECOK1_0329"
/note="coenzyme A binding site [chemical binding]; other
site"
/db_xref="CDD:99870"
misc_feature order(369564..369566,369681..369683,369834..369836)
/gene="prpC"
/locus_tag="ECOK1_0329"
/note="catalytic triad [active]"
/db_xref="CDD:99870"
gene 370065..371516
/gene="prpD"
/locus_tag="ECOK1_0330"
/db_xref="GeneID:12688898"
CDS 370065..371516
/gene="prpD"
/locus_tag="ECOK1_0330"
/EC_number="4.2.1.79"
/note="identified by match to protein family HMM PF03972;
match to protein family HMM TIGR02330"
/codon_start=1
/transl_table=11
/product="2-methylcitrate dehydratase"
/protein_id="YP_006099571.1"
/db_xref="GI:386598065"
/db_xref="GeneID:12688898"
/translation="MSAQINNIRPEFDREIVDIVDYVMNYEISSRVAYDTAHYCLLDT
LGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFN
DTWLAAEWGHPSDNLGGILATADWLSRNAIASGKAPLTMKQVLTGMIKAHEIQGCIAL
ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTG
TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSY
VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDK
KGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPAFT
ADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQ
FPTRQQQRILEVSLDRTRLEQMPVNEYLDLYVI"
misc_feature 370065..371513
/gene="prpD"
/locus_tag="ECOK1_0330"
/note="2-methylcitrate dehydratase; Provisional; Region:
prpD; PRK09425"
/db_xref="CDD:181845"
gene 371556..373442
/gene="prpE"
/locus_tag="ECOK1_0331"
/db_xref="GeneID:12688899"
CDS 371556..373442
/gene="prpE"
/locus_tag="ECOK1_0331"
/EC_number="6.2.1.17"
/note="identified by match to protein family HMM PF00501;
match to protein family HMM TIGR02316"
/codon_start=1
/transl_table=11
/product="propionate--CoA ligase"
/protein_id="YP_006099572.1"
/db_xref="GI:386598066"
/db_xref="GeneID:12688899"
/translation="MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFAR
WFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRS
LGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQ
HIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGV
FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAP
TAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESG
WPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGC
IQTIWGDDDRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTR
EIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDREVAHLQEKAIMALV
DSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQ
AMEE"
misc_feature 371556..373439
/gene="prpE"
/locus_tag="ECOK1_0331"
/note="propionyl-CoA synthetase; Provisional; Region:
prpE; PRK10524"
/db_xref="CDD:182517"
misc_feature 371589..373421
/gene="prpE"
/locus_tag="ECOK1_0331"
/note="Propionyl-CoA synthetase (PrpE); Region: PrpE;
cd05967"
/db_xref="CDD:213314"
misc_feature order(372264..372266,372273..372290,372294..372299)
/gene="prpE"
/locus_tag="ECOK1_0331"
/note="acyl-activating enzyme (AAE) consensus motif; other
site"
/db_xref="CDD:213314"
misc_feature order(372273..372275,372639..372644,372705..372722,
372987..372989,373023..373025,373032..373034,
373065..373067,373329..373331)
/gene="prpE"
/locus_tag="ECOK1_0331"
/note="putative AMP binding site [chemical binding]; other
site"
/db_xref="CDD:213314"
misc_feature order(372273..372275,372396..372401,372552..372554,
372558..372563,372570..372572,372639..372644,
372705..372722,372987..372989,373023..373025,
373032..373034,373056..373067,373272..373274)
/gene="prpE"
/locus_tag="ECOK1_0331"
/note="putative active site [active]"
/db_xref="CDD:213314"
misc_feature order(372396..372398,372558..372563,372570..372572,
372639..372641,373056..373064,373254..373256,
373272..373274)
/gene="prpE"
/locus_tag="ECOK1_0331"
/note="putative CoA binding site [chemical binding]; other
site"
/db_xref="CDD:213314"
gene 373767..375026
/gene="codB"
/locus_tag="ECOK1_0332"
/db_xref="GeneID:12688900"
CDS 373767..375026
/gene="codB"
/locus_tag="ECOK1_0332"
/note="identified by similarity to SP:P0AA82; match to
protein family HMM PF02133; match to protein family HMM
TIGR00800"
/codon_start=1
/transl_table=11
/product="cytosine permease"
/protein_id="YP_006099573.1"
/db_xref="GI:386598067"
/db_xref="GeneID:12688900"
/translation="MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG
TGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLG
GTQVGWFGVGVAMFSIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSVIAVPA
IACLGGYSVWLAVNGMGGLDVLKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFG
RNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNI
WTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPP
VGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGA
LSYLILNPILNRKTTAAMTHVEANSVE"
misc_feature 373773..374978
/gene="codB"
/locus_tag="ECOK1_0332"
/note="nucleobase-cation-symport-1 (NCS1) transporter
CobB-like; solute-binding domain; Region:
SLC-NCS1sbd_CobB-like; cd11484"
/db_xref="CDD:212053"
misc_feature order(373851..373853,373860..373862,374589..374591,
374598..374603)
/gene="codB"
/locus_tag="ECOK1_0332"
/note="Na binding site [ion binding]; other site"
/db_xref="CDD:212053"
misc_feature order(373863..373865,374088..374090,374100..374102,
374373..374378,374382..374384,374604..374606,
374616..374618)
/gene="codB"
/locus_tag="ECOK1_0332"
/note="putative substrate binding site [chemical binding];
other site"
/db_xref="CDD:212053"
gene 375016..376299
/gene="codA"
/locus_tag="ECOK1_0333"
/db_xref="GeneID:12688901"
CDS 375016..376299
/gene="codA"
/locus_tag="ECOK1_0333"
/EC_number="3.5.4.1"
/note="identified by similarity to SP:P25524; match to
protein family HMM PF01979; match to protein family HMM
PF07969"
/codon_start=1
/transl_table=11
/product="cytosine deaminase"
/protein_id="YP_006099574.1"
/db_xref="GI:386598068"
/db_xref="GeneID:12688901"
/translation="MSNNALQTIINAQLPGKEGLWQIHLHDGKISAIDAQSGVMPVTE
NSLDAEQGLVLPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVK
QRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGI
LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDE
IDDEQSRFVETVAALAHREGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVAN
PLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHM
GLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQ
VPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR"
misc_feature 375019..376296
/gene="codA"
/locus_tag="ECOK1_0333"
/note="cytosine deaminase; Provisional; Region: PRK09230"
/db_xref="CDD:181713"
misc_feature 375037..376230
/gene="codA"
/locus_tag="ECOK1_0333"
/note="Bacterial cytosine deaminase and related
metal-dependent hydrolases. Cytosine deaminases (CDs)
catalyze the deamination of cytosine, producing uracil and
ammonia. They play an important role in pyrimidine
salvage. CDs are present in prokaryotes and fungi; Region:
Bact_CD; cd01293"
/db_xref="CDD:30036"
misc_feature order(375199..375201,375205..375207,375658..375660,
375667..375669,375754..375756,375955..375957)
/gene="codA"
/locus_tag="ECOK1_0333"
/note="active site"
/db_xref="CDD:30036"
gene complement(376420..377031)
/locus_tag="ECOK1_0334"
/db_xref="GeneID:12688902"
CDS complement(376420..377031)
/locus_tag="ECOK1_0334"
/note="identified by match to protein family HMM PF00132"
/codon_start=1
/transl_table=11
/product="transferase"
/protein_id="YP_006099575.1"
/db_xref="GI:386598069"
/db_xref="GeneID:12688902"
/translation="MNMSMTERIKAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEV
DKRESLIKEMFATVGENAWVEPPVYFSYGSNIYIGRNFYANFNLTIVDDYTVTIGDNV
LIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGA
GSVVTKDIPPNVVAAGVPCRVIREINDRDKQYYFKDFKVESSV"
misc_feature complement(376423..377031)
/locus_tag="ECOK1_0334"
/note="galactoside O-acetyltransferase; Reviewed; Region:
lacA; PRK09527"
/db_xref="CDD:181930"
misc_feature complement(376486..376992)
/locus_tag="ECOK1_0334"
/note="Maltose O-acetyltransferase (MAT) and Galactoside
O-acetyltransferase (GAT): MAT and GAT catalyze the
CoA-dependent acetylation of the 6-hydroxyl group of their
respective sugar substrates. MAT acetylates maltose and
glucose exclusively at the C6...; Region: LbH_MAT_GAT;
cd03357"
/db_xref="CDD:100047"
misc_feature complement(order(376492..376494,376498..376509,
376534..376539,376543..376545,376552..376557,
376591..376593,376606..376611,376615..376617,
376651..376653,376657..376662,376681..376683,
376687..376689,376693..376695,376699..376701,
376717..376719,376723..376725,376753..376755,
376759..376761,376777..376779,376783..376785,
376819..376821,376954..376956,376981..376983))
/locus_tag="ECOK1_0334"
/note="active site"
/db_xref="CDD:100047"
misc_feature complement(order(376651..376653,376657..376662,
376687..376689,376693..376695,376723..376725,
376753..376755,376759..376761,376777..376779,
376783..376785,376819..376821,376954..376956,
376981..376983))
/locus_tag="ECOK1_0334"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:100047"
misc_feature complement(order(376501..376503,376537..376539,
376549..376554,376561..376563,376567..376569,
376591..376593,376600..376608,376615..376617,
376621..376623,376642..376644,376648..376650,
376666..376671,376675..376683,376687..376689,
376699..376701,376705..376707,376711..376713,
376723..376725,376729..376731,376771..376776,
376822..376827,376831..376833,376909..376911,
376930..376932,376942..376944,376951..376953))
/locus_tag="ECOK1_0334"
/note="trimer interface [polypeptide binding]; other site"
/db_xref="CDD:100047"
misc_feature complement(order(376498..376500,376504..376509,
376534..376539,376552..376557,376591..376593,
376606..376611,376615..376617,376681..376683,
376687..376689,376693..376695,376699..376701))
/locus_tag="ECOK1_0334"
/note="CoA binding site [chemical binding]; other site"
/db_xref="CDD:100047"
gene complement(377097..378350)
/gene="lacY"
/locus_tag="ECOK1_0335"
/db_xref="GeneID:12688903"
CDS complement(377097..378350)
/gene="lacY"
/locus_tag="ECOK1_0335"
/note="identified by similarity to SP:P02920; match to
protein family HMM PF01306; match to protein family HMM
PF07690; match to protein family HMM TIGR00882"
/codon_start=1
/transl_table=11
/product="lactose permease"
/protein_id="YP_006099576.1"
/db_xref="GI:386598070"
/db_xref="GeneID:12688903"
/translation="MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSD
TGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYN
ILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGI
MFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFR
QPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIM
FFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCF
KYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGF
TLISVFTLSGPGPLSLLRRQVNEVA"
misc_feature complement(377112..378350)
/gene="lacY"
/locus_tag="ECOK1_0335"
/note="LacY proton/sugar symporter; Region: LacY_symp;
pfam01306"
/db_xref="CDD:110319"
misc_feature complement(377214..378236)
/gene="lacY"
/locus_tag="ECOK1_0335"
/note="The Major Facilitator Superfamily (MFS) is a large
and diverse group of secondary transporters that includes
uniporters, symporters, and antiporters. MFS proteins
facilitate the transport across cytoplasmic or internal
membranes of a variety of...; Region: MFS; cd06174"
/db_xref="CDD:119392"
misc_feature complement(order(377265..377267,377274..377276,
377280..377282,377289..377294,377301..377306,
377337..377339,377346..377351,377361..377363,
377370..377375,377382..377384,377523..377525,
377535..377537,377544..377546,377556..377558,
377568..377570,377619..377621,377628..377633,
377640..377645,377652..377654,377898..377900,
377916..377921,377928..377933,377973..377975,
377982..377987,377994..377999,378006..378011,
378159..378164,378168..378173,378183..378185,
378192..378197,378204..378206))
/gene="lacY"
/locus_tag="ECOK1_0335"
/note="putative substrate translocation pore; other site"
/db_xref="CDD:119392"
gene complement(378402..381476)
/gene="lacZ"
/locus_tag="ECOK1_0336"
/db_xref="GeneID:12688904"
CDS complement(378402..381476)
/gene="lacZ"
/locus_tag="ECOK1_0336"
/EC_number="3.2.1.23"
/note="identified by similarity to SP:P00722; match to
protein family HMM PF00703; match to protein family HMM
PF02836; match to protein family HMM PF02837; match to
protein family HMM PF02929"
/codon_start=1
/transl_table=11
/product="beta-galactosidase"
/protein_id="YP_006099577.1"
/db_xref="GI:386598071"
/db_xref="GeneID:12688904"
/translation="MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEAR
TDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPDADTVVVPSNWQMHGYDAPIYT
NVTYPITVNPPFVPAENPTGCYSLTFNIDESWLQEGQTRIIFDGVNSAFHLWCNGRWV
GYGQDSRLPSEFDLSAFLHAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHK
PTTQISDFQVTTRFNDDFSRAVLEAEVQMYGELRDELRVTVSLWQGETQVASGTAPFG
GEIIDERGGYADRVTLRLNVENPELWSAEIPNLYRAVVELHTADGTLIEAEACDVGFR
EVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSH
YPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRN
HPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVD
EDQPFPAVPKWSIKKWLSLPGEMRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGG
FVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQ
QQFFQFRLSGRTIEVTSEYLFRHSDNEFLHWMVALDGKPLASGEVPLDVGPQGKQLIE
LPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPSASHAIPQ
LTTSGTDFCIELGNKRWQFNRQSGFLSQMWIGDEKQLLTPLRDQFTRAPLDNDIGVSE
ATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKT
YRIDGHGEMVINVDVAVASDTPHPARIGLTCQLAQVSERVNWLGLGPQENYPDRLTAA
CFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETS
HRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK"
misc_feature complement(378405..381476)
/gene="lacZ"
/locus_tag="ECOK1_0336"
/note="beta-D-galactosidase; Reviewed; Region: lacZ;
PRK09525"
/db_xref="CDD:181928"
misc_feature complement(380820..381332)
/gene="lacZ"
/locus_tag="ECOK1_0336"
/note="Glycosyl hydrolases family 2, sugar binding domain;
Region: Glyco_hydro_2_N; pfam02837"
/db_xref="CDD:202424"
misc_feature complement(380475..380810)
/gene="lacZ"
/locus_tag="ECOK1_0336"
/note="Glycosyl hydrolases family 2; Region:
Glyco_hydro_2; pfam00703"
/db_xref="CDD:201405"
misc_feature complement(379587..380423)
/gene="lacZ"
/locus_tag="ECOK1_0336"
/note="Glycosyl hydrolases family 2, TIM barrel domain;
Region: Glyco_hydro_2_C; pfam02836"
/db_xref="CDD:202423"
misc_feature complement(378411..379229)
/gene="lacZ"
/locus_tag="ECOK1_0336"
/note="Beta galactosidase small chain; Region:
Bgal_small_N; pfam02929"
/db_xref="CDD:111779"
gene complement(381599..382690)
/gene="lacI"
/locus_tag="ECOK1_0337"
/db_xref="GeneID:12688905"
CDS complement(381599..382690)
/gene="lacI"
/locus_tag="ECOK1_0337"
/note="identified by similarity to SP:P03023; match to
protein family HMM PF00356; match to protein family HMM
PF00532"
/codon_start=1
/transl_table=11
/product="lactose operon repressor"
/protein_id="YP_006099578.1"
/db_xref="GI:386598072"
/db_xref="GeneID:12688905"
/translation="MVNVKPVTLYDVAEYAGVSYQTVSRVVNQACHVSAKTREKVEAA
MAELNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMV
ERSGVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACANVPALFLDVSDQTPIN
SIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPIAE
REGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGY
DDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLP
PNTQTASPRALADSLMQLARQVSRLESGQ"
misc_feature complement(381662..382684)
/gene="lacI"
/locus_tag="ECOK1_0337"
/note="lac repressor; Reviewed; Region: lacI; PRK09526"
/db_xref="CDD:181929"
misc_feature complement(382508..382663)
/gene="lacI"
/locus_tag="ECOK1_0337"
/note="Helix-turn-helix (HTH) DNA binding domain of the
LacI family of transcriptional regulators; Region:
HTH_LacI; cd01392"
/db_xref="CDD:143331"
misc_feature complement(order(382511..382516,382520..382525,
382532..382534,382541..382543,382580..382582,
382589..382594,382607..382609,382616..382621,
382625..382639,382661..382663))
/gene="lacI"
/locus_tag="ECOK1_0337"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:143331"
misc_feature complement(382514..382543)
/gene="lacI"
/locus_tag="ECOK1_0337"
/note="domain linker motif; other site"
/db_xref="CDD:143331"
misc_feature complement(381698..382492)
/gene="lacI"
/locus_tag="ECOK1_0337"
/note="Ligand-binding domain of DNA transcription
repressor LacI specific for lactose, a member of the
LacI-GalR family of bacterial transcription regulators;
Region: PBP1_LacI; cd01574"
/db_xref="CDD:107259"
misc_feature complement(order(381860..381862,381944..381946,
382091..382093,382103..382105,382199..382201,
382235..382237,382307..382309,382445..382447,
382454..382459,382475..382477))
/gene="lacI"
/locus_tag="ECOK1_0337"
/note="ligand binding site [chemical binding]; other site"
/db_xref="CDD:107259"
misc_feature complement(order(381917..381919,381929..381931,
381938..381940,382013..382015,382331..382333,
382388..382390,382394..382396,382403..382405,
382430..382432,382439..382441,382451..382453,
382460..382462,382472..382474))
/gene="lacI"
/locus_tag="ECOK1_0337"
/note="dimerization interface (open form) [polypeptide
binding]; other site"
/db_xref="CDD:107259"
misc_feature complement(order(381917..381919,381938..381940,
382328..382330,382430..382432,382448..382450,
382466..382468))
/gene="lacI"
/locus_tag="ECOK1_0337"
/note="dimerization interface (closed form) [polypeptide
binding]; other site"
/db_xref="CDD:107259"
gene 382883..383422
/locus_tag="ECOK1_0338"
/db_xref="GeneID:12688906"
CDS 382883..383422
/locus_tag="ECOK1_0338"
/note="identified by similarity to GB:CAD09197.1"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099579.1"
/db_xref="GI:386598073"
/db_xref="GeneID:12688906"
/translation="MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEE
NKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMNRITIANGDIGFNFTDGNLIKKI
FVDKLTQAQLINGRLAIARLLVDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAE
EQDEDDPYADFKVPDDLMW"
misc_feature 382883..383419
/locus_tag="ECOK1_0338"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG3122"
/db_xref="CDD:225664"
gene complement(383648..384481)
/gene="fghA"
/locus_tag="ECOK1_0339"
/db_xref="GeneID:12688907"
CDS complement(383648..384481)
/gene="fghA"
/locus_tag="ECOK1_0339"
/EC_number="3.1.2.12"
/note="identified by match to protein family HMM PF00756;
match to protein family HMM TIGR02821"
/codon_start=1
/transl_table=11
/product="S-formylglutathione hydrolase"
/protein_id="YP_006099580.1"
/db_xref="GI:386598074"
/db_xref="GeneID:12688907"
/translation="MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAENEKLP
VLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGF
YLNATQAPWNEHYKMYDYIRNELPNLVMHHFPATARKSISGHSMGGLGALVLALRNPD
EYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKDAWLDYDPVSLISQGQRVAEIMVDQG
LSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNM
R"
misc_feature complement(383660..384478)
/gene="fghA"
/locus_tag="ECOK1_0339"
/note="S-formylglutathione hydrolase; Region:
fghA_ester_D; TIGR02821"
/db_xref="CDD:131868"
misc_feature complement(383654..384454)
/gene="fghA"
/locus_tag="ECOK1_0339"
/note="S-formylglutathione hydrolase; Region: PLN02442"
/db_xref="CDD:178061"
gene complement(384574..385683)
/gene="adhC"
/locus_tag="ECOK1_0340"
/db_xref="GeneID:12688908"
CDS complement(384574..385683)
/gene="adhC"
/locus_tag="ECOK1_0340"
/EC_number="1.1.1.284"
/EC_number="1.1.1.1"
/note="identified by similarity to SP:P25437; match to
protein family HMM PF00107; match to protein family HMM
PF08240; match to protein family HMM TIGR02818"
/codon_start=1
/transl_table=11
/product="S-(hydroxymethyl)glutathione dehydrogenase/class
III alcohol dehydrogenase"
/protein_id="YP_006099581.1"
/db_xref="GI:386598075"
/db_xref="GeneID:12688908"
/translation="MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDA
FTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGK
TNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEAN
HEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
TNPKKFELARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALES
AHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGD
IDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY"
misc_feature complement(384580..385683)
/gene="adhC"
/locus_tag="ECOK1_0340"
/note="class III alcohol dehydrogenases; Region:
alcohol_DH_class_III; cd08300"
/db_xref="CDD:176260"
misc_feature complement(384577..385680)
/gene="adhC"
/locus_tag="ECOK1_0340"
/note="S-(hydroxymethyl)glutathione dehydrogenase/class
III alcohol dehydrogenase; Region: adh_III_F_hyde;
TIGR02818"
/db_xref="CDD:131865"
misc_feature complement(order(384745..384747,384817..384819,
385177..385179,385417..385422,385498..385500,
385525..385533,385558..385560,385564..385566))
/gene="adhC"
/locus_tag="ECOK1_0340"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:176260"
misc_feature complement(order(385177..385179,385495..385500,
385564..385566))
/gene="adhC"
/locus_tag="ECOK1_0340"
/note="catalytic Zn binding site [ion binding]; other
site"
/db_xref="CDD:176260"
misc_feature complement(order(384592..384594,384742..384750,
384820..384825,384877..384882,384892..384897,
385015..385017,385027..385032,385090..385104,
385165..385167,385177..385179,385558..385563))
/gene="adhC"
/locus_tag="ECOK1_0340"
/note="NAD binding site [chemical binding]; other site"
/db_xref="CDD:176260"
misc_feature complement(order(385366..385368,385390..385392,
385399..385401,385408..385410))
/gene="adhC"
/locus_tag="ECOK1_0340"
/note="structural Zn binding site [ion binding]; other
site"
/db_xref="CDD:176260"
misc_feature complement(order(384745..384762,384769..384777,
384784..384807,384814..384816,384841..384852,
384871..384876,384907..384909,384922..384924,
385363..385365,385369..385371,385375..385380,
385384..385386,385393..385398))
/gene="adhC"
/locus_tag="ECOK1_0340"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:176260"
gene complement(385718..385993)
/locus_tag="ECOK1_0341"
/db_xref="GeneID:12688909"
CDS complement(385718..385993)
/locus_tag="ECOK1_0341"
/note="identified by similarity to SP:P15753; match to
protein family HMM PF02583"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099582.1"
/db_xref="GI:386598076"
/db_xref="GeneID:12688909"
/translation="MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAA
VRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDDTIELVRAYLK"
misc_feature complement(385724..385987)
/locus_tag="ECOK1_0341"
/note="Transcriptional regulators RcnR and FrmR, and
related domains; this domain family was previously known
as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153"
/db_xref="CDD:197388"
misc_feature complement(order(385802..385804,385814..385816,
385889..385891,385985..385987))
/locus_tag="ECOK1_0341"
/note="putative metal binding site [ion binding]; other
site"
/db_xref="CDD:197388"
misc_feature complement(order(385733..385762,385766..385771,
385799..385801,385808..385816,385820..385828,
385832..385837,385844..385849,385856..385861,
385865..385870,385874..385882,385886..385894,
385898..385909,385916..385921,385925..385930,
385937..385939,385946..385951,385958..385963,
385970..385972))
/locus_tag="ECOK1_0341"
/note="putative homotetramer interface [polypeptide
binding]; other site"
/db_xref="CDD:197388"
misc_feature complement(order(385733..385744,385751..385753,
385814..385816,385826..385828,385835..385837,
385844..385849,385856..385861,385865..385870,
385874..385882,385886..385894,385898..385909,
385916..385921,385925..385930,385937..385939,
385946..385951,385958..385963,385970..385972))
/locus_tag="ECOK1_0341"
/note="putative homodimer interface [polypeptide binding];
other site"
/db_xref="CDD:197388"
misc_feature complement(order(385745..385750,385754..385762,
385766..385771,385799..385804,385808..385813,
385820..385825,385832..385834))
/locus_tag="ECOK1_0341"
/note="putative homodimer-homodimer interface [polypeptide
binding]; other site"
/db_xref="CDD:197388"
misc_feature complement(order(385751..385753,385814..385816))
/locus_tag="ECOK1_0341"
/note="putative allosteric switch controlling residues;
other site"
/db_xref="CDD:197388"
gene complement(386182..386955)
/locus_tag="ECOK1_0342"
/db_xref="GeneID:12688910"
CDS complement(386182..386955)
/locus_tag="ECOK1_0342"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099583.1"
/db_xref="GI:386598077"
/db_xref="GeneID:12688910"
/translation="MIKRTLLAAAIFSALPVYAGLTSITAGYDFTDYSGDHGNRNLAY
AELVAKVENATLLFNLSQGRRDYETEHFNATRGQGAVWYKWNNWLTTRTGIAFADNTP
VFARQDFRQDINLALLPKTLFTTGYRYTKYYDDVEVDAWQGGISLYTGPVITSYRYTH
YDSSDAGGSYSNMISVRLNDPRGTGYTQLWLSRGTGAYTYDWTPETRYGSMKSISLQR
IQPLTEQLNLGLTAGKVWYDTPTDDYNGLQLAAHLTWKF"
gene complement(386957..387481)
/locus_tag="ECOK1_0343"
/db_xref="GeneID:12688911"
CDS complement(386957..387481)
/locus_tag="ECOK1_0343"
/note="identified by match to protein family HMM PF00132"
/codon_start=1
/transl_table=11
/product="putative acyltransferase"
/protein_id="YP_006099584.1"
/db_xref="GI:386598078"
/db_xref="GeneID:12688911"
/translation="MIIDESAGEVVIGANTRICHGAVIQGPVVIGANCLIGNYAFIRP
GTIISNGVRIGFATEIKNAVIEAEATIGPQCFIADSVVANQAYLGAQVRTSNHRLDEQ
PVSVRTPDGIIATGCDKLGCYIGQRSRLGVQVIILPGRIISPNTQLGPRVIVERNLPT
GTYSLRQELIRTGD"
misc_feature complement(387017..387460)
/locus_tag="ECOK1_0343"
/note="Left-handed parallel beta-Helix (LbetaH or LbH)
domain: The alignment contains 5 turns, each containing
three imperfect tandem repeats of a hexapeptide repeat
motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing
hexapeptide repeats are often enzymes...; Region: LbetaH;
cl00160"
/db_xref="CDD:193687"
misc_feature complement(order(387017..387019,387023..387025,
387029..387031,387041..387043,387071..387073,
387077..387082,387095..387097,387197..387199,
387203..387205,387221..387223,387248..387250,
387254..387256,387266..387268,387272..387274))
/locus_tag="ECOK1_0343"
/note="putative trimer interface [polypeptide binding];
other site"
/db_xref="CDD:100038"
misc_feature complement(order(387017..387019,387035..387037,
387071..387073,387086..387091,387095..387097))
/locus_tag="ECOK1_0343"
/note="putative CoA binding site [chemical binding]; other
site"
/db_xref="CDD:100038"
gene complement(387516..388712)
/locus_tag="ECOK1_0344"
/db_xref="GeneID:12688912"
CDS complement(387516..388712)
/locus_tag="ECOK1_0344"
/EC_number="2.4.1.-"
/note="identified by match to protein family HMM PF00535"
/codon_start=1
/transl_table=11
/product="glycosyl transferase family protein"
/protein_id="YP_006099585.1"
/db_xref="GI:386598079"
/db_xref="GeneID:12688912"
/translation="MKTWIFICMAVAILLWFLSTLRRKPSQKKGCIDAIIPAYNEGPC
LAQSLDNLLRNPYFCRVICVNDGSMDNTEAVMAEVKRKWGDRFVAVTQKNTGKGGALM
NGLNYATCDQVFLSDADTYVPPDQDGMGYMLAEIERGADAVGGIPSTALKGAGLLPHI
RATVKLPMIVMKRTLQQLLGGAPFIISGACGMFRTDVLRKFGFSDRTKVEDLDLTWTL
VANGYRIRQANRCIVYPQECNSPREEWRRWRRWIVGYAVCMRLHKRLLFSRFGIFSIF
PMLLVVLYGVGIYLTTWFNEFITTGPHGVVLAMFPLIWVGVVCVIGAFSAWFHRCWLL
VPLAPLSVVYVLLAYAIWIIYGLIAFFTGREPQRDKPTRYSALVEASTAYSHPSVTGT
EKLSEA"
misc_feature complement(387624..388703)
/locus_tag="ECOK1_0344"
/note="Glycosyltransferases, probably involved in cell
wall biogenesis [Cell envelope biogenesis, outer
membrane]; Region: COG1215"
/db_xref="CDD:31408"
misc_feature complement(388080..388610)
/locus_tag="ECOK1_0344"
/note="CESA_like is the cellulose synthase superfamily;
Region: CESA_like; cd06423"
/db_xref="CDD:133045"
misc_feature complement(388356..388364)
/locus_tag="ECOK1_0344"
/note="DXD motif; other site"
/db_xref="CDD:133045"
gene complement(388722..389393)
/locus_tag="ECOK1_0345"
/db_xref="GeneID:12688913"
CDS complement(388722..389393)
/locus_tag="ECOK1_0345"
/note="identified by match to protein family HMM PF02585"
/codon_start=1
/transl_table=11
/product="putative GlcNAc-PI de-N-acetylase"
/protein_id="YP_006099586.1"
/db_xref="GI:386598080"
/db_xref="GeneID:12688913"
/translation="MDKVLDSAILSSANKRKGILAIGAHPDDIELGCGASLARLAQKG
IYIATVVMTTGNSGVDGIIDRHEESRNALKILGCHQTIHLNFADTRAHLQLNDMISAL
ENIIKNQIPSDVEIIRVYTMHDADRHQDHLAVYQASMVACRAIPQILGYETPSTWLSF
MPQVFESVKEEYFSLKLTALKKHKSQSQRDYMRPERLRAVAQFRGQQVNSDLGEGFVI
HKMIL"
misc_feature complement(388779..389369)
/locus_tag="ECOK1_0345"
/note="Uncharacterized proteins, LmbE homologs [Function
unknown]; Region: COG2120"
/db_xref="CDD:32303"
gene complement(389853..390047)
/locus_tag="ECOK1_0346"
/db_xref="GeneID:12688914"
CDS complement(389853..390047)
/locus_tag="ECOK1_0346"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099587.1"
/db_xref="GI:386598081"
/db_xref="GeneID:12688914"
/translation="MNASAARNVLRDEITMIVCSPVLLWEQYSGIKTFIKRISRYRTD
DFILSKKAAKERLNMQLRPL"
gene 390001..390963
/gene="tauA"
/locus_tag="ECOK1_0347"
/db_xref="GeneID:12688915"
CDS 390001..390963
/gene="tauA"
/locus_tag="ECOK1_0347"
/note="identified by match to protein family HMM PF04069;
match to protein family HMM TIGR01729"
/codon_start=1
/transl_table=11
/product="taurine ABC transporter, periplasmic
taurine-binding protein"
/protein_id="YP_006099588.1"
/db_xref="GI:386598082"
/db_xref="GeneID:12688915"
/translation="MVISSRNTFLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNT
FAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVATSQQVPIEVFLLASKL
GNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
IIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHP
EVVKAFAKSAIDAQQPYIANPDAWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQ
QQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ"
misc_feature 390067..390960
/gene="tauA"
/locus_tag="ECOK1_0347"
/note="ABC-type taurine transport system, periplasmic
component [Inorganic ion transport and metabolism];
Region: TauA; COG4521"
/db_xref="CDD:34176"
misc_feature 390127..390729
/gene="tauA"
/locus_tag="ECOK1_0347"
/note="Bacterial periplasmic transport systems use
membrane-bound complexes and substrate-bound,
membrane-associated, periplasmic binding proteins (PBPs)
to transport a wide variety of substrates, such as, amino
acids, peptides, sugars, vitamins and inorganic...;
Region: PBPb; cd00134"
/db_xref="CDD:29040"
misc_feature order(390178..390180,390256..390258,390394..390396,
390526..390528)
/gene="tauA"
/locus_tag="ECOK1_0347"
/note="substrate binding pocket [chemical binding]; other
site"
/db_xref="CDD:29040"
misc_feature order(390475..390477,390487..390489,390505..390507)
/gene="tauA"
/locus_tag="ECOK1_0347"
/note="membrane-bound complex binding site; other site"
/db_xref="CDD:29040"
misc_feature 390601..390618
/gene="tauA"
/locus_tag="ECOK1_0347"
/note="hinge residues; other site"
/db_xref="CDD:29040"
gene 390976..391743
/gene="tauB"
/locus_tag="ECOK1_0348"
/db_xref="GeneID:12688916"
CDS 390976..391743
/gene="tauB"
/locus_tag="ECOK1_0348"
/EC_number="3.6.3.36"
/note="identified by similarity to SP:Q47538; match to
protein family HMM PF00005"
/codon_start=1
/transl_table=11
/product="taurine ABC transporter ATP-binding protein"
/protein_id="YP_006099589.1"
/db_xref="GI:386598083"
/db_xref="GeneID:12688916"
/translation="MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLL
NLIAGFVPYQHGSIQLAGKGIQGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGVEK
MQRLEIAHQMVKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD
AFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPGPGRVLERLPLNFA
RRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS"
misc_feature 390976..391740
/gene="tauB"
/locus_tag="ECOK1_0348"
/note="taurine transporter ATP-binding subunit;
Provisional; Region: tauB; PRK11248"
/db_xref="CDD:183056"
misc_feature 390979..391626
/gene="tauB"
/locus_tag="ECOK1_0348"
/note="ATP-binding cassette domain of the nitrate and
sulfonate transporters; Region:
ABC_NrtD_SsuB_transporters; cd03293"
/db_xref="CDD:213260"
misc_feature 391075..391098
/gene="tauB"
/locus_tag="ECOK1_0348"
/note="Walker A/P-loop; other site"
/db_xref="CDD:213260"
misc_feature order(391084..391089,391093..391101,391204..391206,
391432..391437,391534..391536)
/gene="tauB"
/locus_tag="ECOK1_0348"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:213260"
misc_feature 391195..391206
/gene="tauB"
/locus_tag="ECOK1_0348"
/note="Q-loop/lid; other site"
/db_xref="CDD:213260"
misc_feature 391360..391389
/gene="tauB"
/locus_tag="ECOK1_0348"
/note="ABC transporter signature motif; other site"
/db_xref="CDD:213260"
misc_feature 391420..391437
/gene="tauB"
/locus_tag="ECOK1_0348"
/note="Walker B; other site"
/db_xref="CDD:213260"
misc_feature 391444..391455
/gene="tauB"
/locus_tag="ECOK1_0348"
/note="D-loop; other site"
/db_xref="CDD:213260"
misc_feature 391522..391542
/gene="tauB"
/locus_tag="ECOK1_0348"
/note="H-loop/switch region; other site"
/db_xref="CDD:213260"
gene 391740..392567
/gene="tauC"
/locus_tag="ECOK1_0349"
/db_xref="GeneID:12688917"
CDS 391740..392567
/gene="tauC"
/locus_tag="ECOK1_0349"
/note="identified by similarity to Q47539; match to
protein family HMM PF00528"
/codon_start=1
/transl_table=11
/product="taurine uptake ABC transporter, permease
protein"
/protein_id="YP_006099590.1"
/db_xref="GI:386598084"
/db_xref="GeneID:12688917"
/translation="MSVLINEKLHSHRLKWRWPLSRQVTLSIGTLAVLLTVWWAVAAL
QLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHLAASLTRIVLALLAAVLIGIPVG
IAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAE
LIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ"
misc_feature 391872..392564
/gene="tauC"
/locus_tag="ECOK1_0349"
/note="ABC-type nitrate/sulfonate/bicarbonate transport
system, permease component [Inorganic ion transport and
metabolism]; Region: TauC; COG0600"
/db_xref="CDD:30945"
misc_feature 392028..392405
/gene="tauC"
/locus_tag="ECOK1_0349"
/note="Transmembrane subunit (TM) found in Periplasmic
Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
transporters which generally bind type 2 PBPs. These types
of transporters consist of a PBP, two TMs, and two
cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
cd06261"
/db_xref="CDD:119394"
misc_feature order(392028..392030,392037..392042,392055..392057,
392082..392093,392097..392126,392133..392138,
392142..392144,392190..392195,392199..392201,
392205..392207,392214..392219,392223..392225,
392235..392240,392247..392249,392298..392300,
392340..392345,392352..392354,392373..392384,
392391..392396)
/gene="tauC"
/locus_tag="ECOK1_0349"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:119394"
misc_feature order(392100..392144,392373..392390)
/gene="tauC"
/locus_tag="ECOK1_0349"
/note="conserved gate region; other site"
/db_xref="CDD:119394"
misc_feature order(392142..392144,392175..392177,392391..392393)
/gene="tauC"
/locus_tag="ECOK1_0349"
/note="putative PBP binding loops; other site"
/db_xref="CDD:119394"
misc_feature order(392250..392288,392304..392309,392319..392321)
/gene="tauC"
/locus_tag="ECOK1_0349"
/note="ABC-ATPase subunit interface; other site"
/db_xref="CDD:119394"
gene 392564..393415
/gene="tauD"
/locus_tag="ECOK1_0350"
/db_xref="GeneID:12688918"
CDS 392564..393415
/gene="tauD"
/locus_tag="ECOK1_0350"
/EC_number="1.14.11.17"
/note="identified by similarity to SP:P37610; match to
protein family HMM PF02668"
/codon_start=1
/transl_table=11
/product="taurine dioxygenase"
/protein_id="YP_006099591.1"
/db_xref="GI:386598085"
/db_xref="GeneID:12688918"
/translation="MSERLSITPLGPYIGAQITGADLTRPLSDNQFEQLYHAVLRHHV
VFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDV
TFIQTPPAGAILAAKELPSTGGDTLWASGIAAYEALSVPFRQLLSGLRAEHDFRKSFP
EYKYRKTEAEHQRWREAVAKNPPLLHPVVRTHPVTGKQALFVNEGFTTRIVDVSEKES
EALLGFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGD
IPFYRAG"
misc_feature 392564..393412
/gene="tauD"
/locus_tag="ECOK1_0350"
/note="Probable taurine catabolism dioxygenase [Secondary
metabolites biosynthesis, transport, and catabolism];
Region: TauD; COG2175"
/db_xref="CDD:32358"
misc_feature 392570..393400
/gene="tauD"
/locus_tag="ECOK1_0350"
/note="taurine dioxygenase; Reviewed; Region: tauD;
PRK09553"
/db_xref="CDD:181947"
misc_feature order(392873..392875,392888..392890,393029..393031,
393371..393373,393377..393379)
/gene="tauD"
/locus_tag="ECOK1_0350"
/note="substrate binding pocket [chemical binding]; other
site"
/db_xref="CDD:29325"
misc_feature order(392939..392941,393326..393328,393359..393361)
/gene="tauD"
/locus_tag="ECOK1_0350"
/note="active site"
/db_xref="CDD:29325"
gene complement(393455..394429)
/gene="hemB"
/locus_tag="ECOK1_0351"
/db_xref="GeneID:12688919"
CDS complement(393455..394429)
/gene="hemB"
/locus_tag="ECOK1_0351"
/EC_number="4.2.1.24"
/note="identified by similarity to SP:P0ACB3; match to
protein family HMM PF00490"
/codon_start=1
/transl_table=11
/product="delta-aminolevulinic acid dehydratase"
/protein_id="YP_006099592.1"
/db_xref="GI:386598086"
/db_xref="GeneID:12688919"
/translation="MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDY
KAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARM
SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGAD
FIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKS
YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEY
AMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR"
misc_feature complement(393470..394405)
/gene="hemB"
/locus_tag="ECOK1_0351"
/note="Porphobilinogen synthase (PBGS), which is also
called delta-aminolevulinic acid dehydratase (ALAD),
catalyzes the condensation of two 5-aminolevulinic acid
(ALA) molecules to form the pyrrole porphobilinogen (PBG),
which is the second step in the...; Region: ALAD_PBGS;
cd00384"
/db_xref="CDD:238226"
misc_feature complement(order(393521..393523,393530..393532,
393542..393544,393596..393598,393668..393682,
393734..393739,393746..393748,393764..393766,
393773..393775,393830..393838,393923..393928,
394007..394012,394277..394279,394286..394288,
394358..394360,394391..394396,394403..394405))
/gene="hemB"
/locus_tag="ECOK1_0351"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:238226"
misc_feature complement(order(393494..393496,393611..393613,
393620..393622,393689..393691,393770..393772,
393782..393784,393800..393802,393815..393820,
393827..393829,393845..393847,393935..393937,
394040..394042,394064..394066,394070..394072,
394076..394078))
/gene="hemB"
/locus_tag="ECOK1_0351"
/note="active site"
/db_xref="CDD:238226"
misc_feature complement(order(393689..393691,393845..393847))
/gene="hemB"
/locus_tag="ECOK1_0351"
/note="Schiff base residues; other site"
/db_xref="CDD:238226"
gene 394955..397942
/locus_tag="ECOK1_0352"
/db_xref="GeneID:12688920"
CDS 394955..397942
/locus_tag="ECOK1_0352"
/note="identified by match to protein family HMM PF03212;
match to protein family HMM PF03797; match to protein
family HMM TIGR01414"
/codon_start=1
/transl_table=11
/product="outer membrane autotransporter"
/protein_id="YP_006099593.1"
/db_xref="GI:386598087"
/db_xref="GeneID:12688920"
/translation="MHSWKKKLVVSQLALACTLAITSQANAANYDTWGYHDNTTTDLV
WPYDTDNDGIADAGGMDPMGSDGNYVTYNGFVYYNNANGDFDTVFKGDTVNGTISTYY
LNHDYASGSVNQVDISNSVIHGAITSELPFGYYSITPAEVNAKGEVVTPQTYNGYNFY
NGITTDLDYNWYDGDVFTLNVSNSTIDDDYEALYFTDTYLDGDKSKSTNETFYTALGV
AVNLDVESNINITNNSRVAGIALSEGNTSNTTYTSEYHQWDNNINVSNSTVTSGSQTP
LEESNGFFGKSAEPSDYAGNGGENDVALSFSDNAGSNYSMKNNVNFDHSTLLGDVEFT
SHWNNDGVFFYSTGHDSNGDGVLDTNGGWVDDAQNVDELNITLNNGSKWVGSANMSAE
VIAPADMYDVAPNSLTPGATIEANDWGRIIDNKVFQSGVFNVALNNGSEWNTVNSSVI
DTLAVNNGSQVNVTDSSLVSDTIGLTNGSSLNIGEDGLVATDHLTVDSYSTVNLTEST
GWNNYSNLYANIITVTNGGVLDVNVDQFDTEAFRTDKLELTSGNIADHNGNVVSGVFD
INSSDYVLNADLVNDRTWDTAQANYGYGVVAMNSDGHLTINGNGDVDNGTELDNSSVD
NVVAATGNYKVRIDNATGAGAIADYKDKEIIYVNDVNSNATFSAANKADLGAYTYQAE
QRGNTVVLQQMELTDYANMALSIPSANTNIWNLEQDTVGTRLTNSRHGLADNGGAWVS
YFGGNFNGDNGTINYDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMNDRSGQVD
QDSQTAYIYSSAHFANNVFVDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFGLKA
GYDFKLGDAGYVTPYGSVSGLFQSGDDYQLSNDMKVDGQSYDSMRYELGVDAGYTFTY
SEDQALTPYFKLAYVYDDSNNDNDVNGDSIDNGTEGSAVRVGLGTQFSFTKNFSAYTD
ANYLGGGDVDQDWSANVGVKYTW"
misc_feature 396563..397015
/locus_tag="ECOK1_0352"
/note="Pertactin-like passenger domains (virulence
factors) of autotransporter proteins of the type V
secretion system. Autotransporters are proteins used by
Gram-negative bacteria to transport proteins across their
outer membranes. The C-terminal (beta) domain...; Region:
PL_Passenger_AT; cd00253"
/db_xref="CDD:29327"
misc_feature 396722..397939
/locus_tag="ECOK1_0352"
/note="outer membrane autotransporter barrel domain;
Region: autotrans_barl; TIGR01414"
/db_xref="CDD:162346"
misc_feature 397148..397894
/locus_tag="ECOK1_0352"
/note="Autotransporter beta-domain; Region:
Autotransporter; pfam03797"
/db_xref="CDD:202770"
gene 398028..398651
/locus_tag="ECOK1_0353"
/db_xref="GeneID:12688921"
CDS 398028..398651
/locus_tag="ECOK1_0353"
/note="identified by similarity to GB:AAN78957.1"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099594.1"
/db_xref="GI:386598088"
/db_xref="GeneID:12688921"
/translation="MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSNVNSEDT
FVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQT
ITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRI
GVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY"
misc_feature 398028..398648
/locus_tag="ECOK1_0353"
/note="putative DNA-binding transcriptional regulator;
Provisional; Region: PRK11832"
/db_xref="CDD:183332"
gene complement(398652..399809)
/gene="ampH"
/locus_tag="ECOK1_0354"
/db_xref="GeneID:12688922"
CDS complement(398652..399809)
/gene="ampH"
/locus_tag="ECOK1_0354"
/note="identified by similarity to SP:P0AD70; match to
protein family HMM PF00144"
/codon_start=1
/transl_table=11
/product="penicillin-binding protein AmpH"
/protein_id="YP_006099595.1"
/db_xref="GI:386598089"
/db_xref="GeneID:12688922"
/translation="MKRSLLFSAVLYAASLTSVHTAQPITEPEFASDIVDRYADHIFY
GSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLDSVIRIASLTKLMTSEMLVKLLD
QGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
REQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMK
DTTYTPSPDQCRRLMVAERGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQR
SNQADRMQTLIYQRAQFTKVIGMDVPGKADALGLGWVYMAPKEGRPGIIQKTGGGGGF
ITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS"
misc_feature complement(398676..399809)
/gene="ampH"
/locus_tag="ECOK1_0354"
/note="beta-lactam binding protein AmpH; Provisional;
Region: PRK10662"
/db_xref="CDD:182627"
misc_feature complement(398721..399809)
/gene="ampH"
/locus_tag="ECOK1_0354"
/note="Beta-lactamase class C and other penicillin binding
proteins [Defense mechanisms]; Region: AmpC; COG1680"
/db_xref="CDD:31866"
gene 400161..401381
/gene="smbA"
/locus_tag="ECOK1_0355"
/db_xref="GeneID:12688923"
CDS 400161..401381
/gene="smbA"
/locus_tag="ECOK1_0355"
/note="identified by similarity to SP:P0AFY6; match to
protein family HMM PF05992; match to protein family HMM
PF06472"
/codon_start=1
/transl_table=11
/product="protein SbmA"
/protein_id="YP_006099596.1"
/db_xref="GI:386598090"
/db_xref="GeneID:12688923"
/translation="MFKSFFPKPGTFFLSAFVWALIAVIFWQAGGGDWVARITGASGQ
IPISAARFWSLDFLIFYAYYIVCVGLFALFWFIYSPHRWQYWSILGTALIIFVTWFLV
EVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVS
HYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
FLPVLVTLSAHVPELPIVGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVE
AAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFG
LFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHE
LDGDKIQEVTHTLS"
misc_feature 400161..401378
/gene="smbA"
/locus_tag="ECOK1_0355"
/note="microcin B17 transporter; Reviewed; Region:
PRK11098"
/db_xref="CDD:182960"
gene 401394..402488
/locus_tag="ECOK1_0356"
/db_xref="GeneID:12688924"
CDS 401394..402488
/locus_tag="ECOK1_0356"
/note="identified by match to protein family HMM PF07759"
/codon_start=1
/transl_table=11
/product="putative lipoprotein"
/protein_id="YP_006099597.1"
/db_xref="GI:386598091"
/db_xref="GeneID:12688924"
/translation="MSRVNPLSSLSLLAVLILAGCSSQAPQPLKKGEKAIDVASVVRQ
KMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIA
WQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSAIFDDLISMVPM
GQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLL
NYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYDSKEPGKTE
LATRKLAGKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAEAKTGKSLPREMLPGI
QLESPKITRNLTTAWFAKRVDERRARCMKQ"
misc_feature 401535..402482
/locus_tag="ECOK1_0356"
/note="Protein of unknown function (DUF1615); Region:
DUF1615; pfam07759"
/db_xref="CDD:149043"
gene complement(402547..402855)
/locus_tag="ECOK1_0357"
/db_xref="GeneID:12688925"
CDS complement(402547..402855)
/locus_tag="ECOK1_0357"
/note="identified by similarity to SP:P0AAP7"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099598.1"
/db_xref="GI:386598092"
/db_xref="GeneID:12688925"
/translation="MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNL
LVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIPFLVGCLIFAVVALWLHWRHRRQ
"
misc_feature complement(402553..402855)
/locus_tag="ECOK1_0357"
/note="Protein of unknown function (DUF2755); Region:
DUF2755; pfam10954"
/db_xref="CDD:151401"
gene 402983..403327
/locus_tag="ECOK1_0358"
/db_xref="GeneID:12688926"
CDS 402983..403327
/locus_tag="ECOK1_0358"
/note="identified by similarity to GB:AAZ87131.1"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099599.1"
/db_xref="GI:386598093"
/db_xref="GeneID:12688926"
/translation="MNLRCESQNSNLKLNLLTIAKVLSTPQTVVTEYARMLFFVNGAA
MNLPVKIRRDWHYYAFAIGLIFILNGVVGLLGFEAKGWQTYAVGLVTWVISFWLAGLI
IRRRDEETENAQ"
misc_feature 403115..403324
/locus_tag="ECOK1_0358"
/note="Protein of unknown function (DUF2754); Region:
DUF2754; pfam10953"
/db_xref="CDD:151400"
gene complement(403351..404445)
/gene="ddlA"
/locus_tag="ECOK1_0359"
/db_xref="GeneID:12688927"
CDS complement(403351..404445)
/gene="ddlA"
/locus_tag="ECOK1_0359"
/EC_number="6.3.2.4"
/note="identified by similarity to SP:P0A6J8; match to
protein family HMM PF01820; match to protein family HMM
PF02222; match to protein family HMM PF07478; match to
protein family HMM TIGR01205"
/codon_start=1
/transl_table=11
/product="D-alanine--D-alanine ligase"
/protein_id="YP_006099600.1"
/db_xref="GI:386598094"
/db_xref="GeneID:12688927"
/translation="MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGID
KQGQWHVSDASNYLLNADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVI
FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFIT
LTRANRHNISFAEVESKLGLPLFVKPANQGSSVGVSKVTSEEQYTIAVDLAFEFDHKV
IVEQGIKGREIECAVLGNDNPQASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAP
EINDKIRAIAVQAYQTLGCAGMARVDVFLTPENEVVINEINTLPGFTNISMYPKLWQA
SGLGYTDLITRLIELALERHAADNALKTTM"
misc_feature complement(403390..404445)
/gene="ddlA"
/locus_tag="ECOK1_0359"
/note="D-alanyl-alanine synthetase A; Reviewed; Region:
ddl; PRK01966"
/db_xref="CDD:234993"
misc_feature complement(404056..404436)
/gene="ddlA"
/locus_tag="ECOK1_0359"
/note="D-ala D-ala ligase N-terminus; Region:
Dala_Dala_lig_N; pfam01820"
/db_xref="CDD:216721"
misc_feature complement(403402..404007)
/gene="ddlA"
/locus_tag="ECOK1_0359"
/note="D-ala D-ala ligase C-terminus; Region:
Dala_Dala_lig_C; pfam07478"
/db_xref="CDD:203643"
gene 404523..404645
/locus_tag="ECOK1_0360"
/db_xref="GeneID:12688928"
CDS 404523..404645
/locus_tag="ECOK1_0360"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099601.1"
/db_xref="GI:386598095"
/db_xref="GeneID:12688928"
/translation="MLQSSADKASNVLVKKVRYLKDVCKITKMMNGKLIYSWLK"
gene 404908..405168
/locus_tag="ECOK1_0361"
/db_xref="GeneID:12688929"
CDS 404908..405168
/locus_tag="ECOK1_0361"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099602.1"
/db_xref="GI:386598096"
/db_xref="GeneID:12688929"
/translation="MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQND
QQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLRHPRQ"
misc_feature 404908..405165
/locus_tag="ECOK1_0361"
/note="anti-RssB factor; Provisional; Region: PRK10244"
/db_xref="CDD:236666"
gene 405269..406684
/gene="phoA"
/locus_tag="ECOK1_0362"
/db_xref="GeneID:12688930"
CDS 405269..406684
/gene="phoA"
/locus_tag="ECOK1_0362"
/EC_number="3.1.3.1"
/note="identified by similarity to SP:P00634; match to
protein family HMM PF00245"
/codon_start=1
/transl_table=11
/product="alkaline phosphatase"
/protein_id="YP_006099603.1"
/db_xref="GI:386598097"
/db_xref="GeneID:12688930"
/translation="MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGA
RRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPL
TGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKA
AGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLL
NARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDTASLNSVTEANQQKP
LLGLFADGNMPVRWQGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSK
NEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKDGNTLVIVTADH
AHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAAN
VVGLTDQTDLFYTMKAALGLK"
misc_feature 405269..406681
/gene="phoA"
/locus_tag="ECOK1_0362"
/note="alkaline phosphatase; Provisional; Region:
PRK10518"
/db_xref="CDD:236706"
misc_feature 405443..406678
/gene="phoA"
/locus_tag="ECOK1_0362"
/note="Alkaline phosphatase homologues; alkaline
phosphatases are non-specific phosphomonoesterases that
catalyze the hydrolysis reaction via a phosphoseryl
intermediate to produce inorganic phosphate and the
corresponding alcohol, optimally at high pH; Region:
alkPPc; cd00016"
/db_xref="CDD:237983"
misc_feature order(405443..405451,405497..405502,405509..405511,
405518..405523,405560..405562,405569..405571,
405575..405583,405587..405589,405593..405595,
405599..405601,405629..405631,405668..405676,
405704..405706,405719..405721,406451..406453,
406457..406468,406523..406528,406541..406546,
406565..406567,406571..406582,406586..406588,
406625..406636,406640..406645,406652..406654)
/gene="phoA"
/locus_tag="ECOK1_0362"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:237983"
misc_feature order(405485..405487,405635..405640,405791..405793,
405797..405799,405830..405832,406298..406300,
406313..406318,406325..406327,406439..406444,
406568..406570)
/gene="phoA"
/locus_tag="ECOK1_0362"
/note="active site"
/db_xref="CDD:237983"
gene 406803..407123
/gene="psiF"
/locus_tag="ECOK1_0363"
/db_xref="GeneID:12688931"
CDS 406803..407123
/gene="psiF"
/locus_tag="ECOK1_0363"
/note="identified by match to protein family HMM PF07769"
/codon_start=1
/transl_table=11
/product="phosphate starvation-inducible protein PsiF"
/protein_id="YP_006099604.1"
/db_xref="GI:386598098"
/db_xref="GeneID:12688931"
/translation="MKITLLVTLLFGLVFLTTVGAAERTLTPQQQRMTSCNQQATAQA
LKGDARKTYMSDCLKNSKSAPGEKSLTPQQQKMRECNNQATQQSLKGDDRNKFMSACL
KKAA"
misc_feature 406863..407120
/gene="psiF"
/locus_tag="ECOK1_0363"
/note="hypothetical protein; Provisional; Region:
PRK11505"
/db_xref="CDD:183165"
misc_feature 406878..406979
/gene="psiF"
/locus_tag="ECOK1_0363"
/note="psiF repeat; Region: PsiF_repeat; pfam07769"
/db_xref="CDD:203759"
misc_feature 407007..407111
/gene="psiF"
/locus_tag="ECOK1_0363"
/note="psiF repeat; Region: PsiF_repeat; pfam07769"
/db_xref="CDD:203759"
gene 407225..408340
/locus_tag="ECOK1_0364"
/db_xref="GeneID:12688932"
CDS 407225..408340
/locus_tag="ECOK1_0364"
/note="identified by match to protein family HMM PF00990;
match to protein family HMM PF05230; match to protein
family HMM TIGR00254"
/codon_start=1
/transl_table=11
/product="MASE2 domain/diguanylate cyclase"
/protein_id="YP_006099605.1"
/db_xref="GI:386598099"
/db_xref="GeneID:12688932"
/translation="MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLP
RAVGLAGMFLPIASTLVSHPSPGWWWLLLVGWAFVWPHLAWQIASRAVDPLSREIYNL
KTDAVLAGMWVGVMGVNALPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLEL
TGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGV
YNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQ
ITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVTLRISVG
VAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA"
misc_feature 407240..408337
/locus_tag="ECOK1_0364"
/note="diguanylate cyclase AdrA; Provisional; Region:
adrA; PRK10245"
/db_xref="CDD:182329"
misc_feature 407339..407611
/locus_tag="ECOK1_0364"
/note="MASE2 domain; Region: MASE2; pfam05230"
/db_xref="CDD:147434"
misc_feature 407855..408322
/locus_tag="ECOK1_0364"
/note="Diguanylate-cyclase (DGC) or GGDEF domain; Region:
GGDEF; cd01949"
/db_xref="CDD:143635"
misc_feature order(407966..407968,408095..408097)
/locus_tag="ECOK1_0364"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:143635"
misc_feature order(407981..407983,407990..407995,408005..408007,
408017..408019,408083..408085,408089..408100)
/locus_tag="ECOK1_0364"
/note="active site"
/db_xref="CDD:143635"
misc_feature order(408071..408073,408155..408157)
/locus_tag="ECOK1_0364"
/note="I-site; other site"
/db_xref="CDD:143635"
gene complement(408357..409166)
/gene="proC"
/locus_tag="ECOK1_0365"
/db_xref="GeneID:12688933"
CDS complement(408357..409166)
/gene="proC"
/locus_tag="ECOK1_0365"
/EC_number="1.5.1.2"
/note="identified by match to protein family HMM PF03446;
match to protein family HMM PF03807; match to protein
family HMM TIGR00112"
/codon_start=1
/transl_table=11
/product="pyrroline-5-carboxylate reductase"
/protein_id="YP_006099606.1"
/db_xref="GI:386598100"
/db_xref="GeneID:12688933"
/translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVTV
LHDQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGITL
DQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLET
GEHPGTLKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS"
misc_feature complement(408360..409166)
/gene="proC"
/locus_tag="ECOK1_0365"
/note="pyrroline-5-carboxylate reductase; Reviewed;
Region: PRK11880"
/db_xref="CDD:183357"
misc_feature complement(408360..409160)
/gene="proC"
/locus_tag="ECOK1_0365"
/note="pyrroline-5-carboxylate reductase; Region:
PLN02688"
/db_xref="CDD:178291"
gene 409286..409744
/locus_tag="ECOK1_0366"
/db_xref="GeneID:12688934"
CDS 409286..409744
/locus_tag="ECOK1_0366"
/note="identified by similarity to SP:Q3Z523; match to
protein family HMM PF02639"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099607.1"
/db_xref="GI:386598101"
/db_xref="GeneID:12688934"
/translation="MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRF
IRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATI
RERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG"
misc_feature 409286..409738
/locus_tag="ECOK1_0366"
/note="hypothetical protein; Validated; Region: PRK00124"
/db_xref="CDD:178882"
gene 409927..410451
/gene="aroL"
/locus_tag="ECOK1_0367"
/db_xref="GeneID:12688935"
CDS 409927..410451
/gene="aroL"
/locus_tag="ECOK1_0367"
/EC_number="2.7.1.71"
/note="identified by match to protein family HMM PF01202"
/codon_start=1
/transl_table=11
/product="shikimate kinase"
/protein_id="YP_006099608.1"
/db_xref="GI:386598102"
/db_xref="GeneID:12688935"
/translation="MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDLWLQSQLNMT
VAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCA
PVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQV
ISEIRSALAQTINC"
misc_feature 409927..410448
/gene="aroL"
/locus_tag="ECOK1_0367"
/note="Shikimate kinase [Amino acid transport and
metabolism]; Region: AroK; COG0703"
/db_xref="CDD:31047"
misc_feature 409936..410397
/gene="aroL"
/locus_tag="ECOK1_0367"
/note="Shikimate kinase (SK) is the fifth enzyme in the
shikimate pathway, a seven-step biosynthetic pathway which
converts erythrose-4-phosphate to chorismic acid, found in
bacteria, fungi and plants. Chorismic acid is a important
intermediate in the synthesis...; Region: SK; cd00464"
/db_xref="CDD:30188"
misc_feature order(409960..409977,410254..410256,410284..410286)
/gene="aroL"
/locus_tag="ECOK1_0367"
/note="ADP binding site [chemical binding]; other site"
/db_xref="CDD:30188"
misc_feature order(409972..409974,410020..410022,410026..410028)
/gene="aroL"
/locus_tag="ECOK1_0367"
/note="magnesium binding site [ion binding]; other site"
/db_xref="CDD:30188"
misc_feature order(410026..410028,410098..410100,410107..410109,
410158..410166,410341..410343)
/gene="aroL"
/locus_tag="ECOK1_0367"
/note="putative shikimate binding site; other site"
/db_xref="CDD:30188"
gene 410501..410692
/locus_tag="ECOK1_0368"
/db_xref="GeneID:12688936"
CDS 410501..410692
/locus_tag="ECOK1_0368"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099609.1"
/db_xref="GI:386598103"
/db_xref="GeneID:12688936"
/translation="MPTKPPYPREAYIVTIDKGKPGQTVTWYQLRADHPKPDSLISEH
PTAQEAMDAKKRYEDPDKE"
misc_feature 410501..410689
/locus_tag="ECOK1_0368"
/note="hypothetical protein; Provisional; Region:
PRK10380"
/db_xref="CDD:182421"
gene 410950..411627
/gene="aroM"
/locus_tag="ECOK1_0369"
/db_xref="GeneID:12688937"
CDS 410950..411627
/gene="aroM"
/locus_tag="ECOK1_0369"
/note="identified by match to protein family HMM PF07302"
/codon_start=1
/transl_table=11
/product="AroM protein"
/protein_id="YP_006099610.1"
/db_xref="GI:386598104"
/db_xref="GeneID:12688937"
/translation="MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREE
VMAEYAPEAGEDTILTLLNDNHLAHVSRRKVERDLQGVVEVLDNQGYDVIILMSTANI
SSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEELLTVQAQKWQILQKPPVFSL
GNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFNQRHRDLLQKQLDVPVLLSNVLIAR
LAAELLM"
misc_feature 410950..411621
/gene="aroM"
/locus_tag="ECOK1_0369"
/note="hypothetical protein; Provisional; Region:
PRK10481"
/db_xref="CDD:182491"
gene 411699..411983
/locus_tag="ECOK1_0370"
/db_xref="GeneID:12688938"
CDS 411699..411983
/locus_tag="ECOK1_0370"
/note="identified by match to protein family HMM PF06865"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099611.1"
/db_xref="GI:386598105"
/db_xref="GeneID:12688938"
/translation="MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEE
MTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL"
misc_feature 411699..411980
/locus_tag="ECOK1_0370"
/note="hypothetical protein; Provisional; Region:
PRK10579"
/db_xref="CDD:182565"
gene complement(412087..412230)
/locus_tag="ECOK1_0371"
/db_xref="GeneID:12688939"
CDS complement(412087..412230)
/locus_tag="ECOK1_0371"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099612.1"
/db_xref="GI:386598106"
/db_xref="GeneID:12688939"
/translation="MPFGANDHCDFAAMHATIHHLIYLLSSPVPQQYLEIFADIYINL
DEL"
gene 412191..412472
/locus_tag="ECOK1_0372"
/db_xref="GeneID:12688940"
CDS 412191..412472
/locus_tag="ECOK1_0372"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099613.1"
/db_xref="GI:386598107"
/db_xref="GeneID:12688940"
/translation="MLQSRNDHLRQTALHNAHTPVLLLTTLTEPQERSLAINNSQLAA
DVKTAWLKEEPSLLLFVEQPDLSLLRDLVKTGATRKIRSEARHRLEEKQ"
misc_feature 412227..412469
/locus_tag="ECOK1_0372"
/note="Protein of unknown function (DUF2773); Region:
DUF2773; pfam10971"
/db_xref="CDD:151418"
gene complement(412630..413541)
/locus_tag="ECOK1_0373"
/db_xref="GeneID:12688941"
CDS complement(412630..413541)
/locus_tag="ECOK1_0373"
/note="identified by similarity to SP:P36767; match to
protein family HMM PF04381"
/codon_start=1
/transl_table=11
/product="putative recombination-associated exonuclease
RdgC"
/protein_id="YP_006099614.1"
/db_xref="GI:386598108"
/db_xref="GeneID:12688941"
/translation="MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMG
WVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKT
EKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
LPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEE
ITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFD
ADFILMTGELAALIQNLIEGLGGEAQR"
misc_feature complement(412633..413538)
/locus_tag="ECOK1_0373"
/note="DNA recombination-dependent growth factor C [DNA
replication, recombination, and repair]; Region: RdgC;
COG2974"
/db_xref="CDD:225521"
gene 413665..414573
/gene="mak"
/locus_tag="ECOK1_0374"
/db_xref="GeneID:12688942"
CDS 413665..414573
/gene="mak"
/locus_tag="ECOK1_0374"
/EC_number="2.7.1.-"
/note="identified by similarity to SP:P23917; match to
protein family HMM PF00480"
/codon_start=1
/transl_table=11
/product="manno(fructo)kinase"
/protein_id="YP_006099615.1"
/db_xref="GI:386598109"
/db_xref="GeneID:12688942"
/translation="MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIA
TLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRL
ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPL
PWMDEDELRYREEVPCYCGKQGCIETFISGTGFATDYRRLSGHALKGSEIIRLVEESD
PVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVPQLIKQFVFGGE
CETPVRKAKHGDSSGVRGAAWLWPQE"
misc_feature 413665..414567
/gene="mak"
/locus_tag="ECOK1_0374"
/note="fructokinase; Reviewed; Region: PRK09557"
/db_xref="CDD:236565"
misc_feature 413671..414132
/gene="mak"
/locus_tag="ECOK1_0374"
/note="Nucleotide-Binding Domain of the sugar
kinase/HSP70/actin superfamily; Region:
NBD_sugar-kinase_HSP70_actin; cd00012"
/db_xref="CDD:212657"
misc_feature order(413680..413691,413695..413697,413701..413703,
413977..413979,414049..414060)
/gene="mak"
/locus_tag="ECOK1_0374"
/note="nucleotide binding site [chemical binding]; other
site"
/db_xref="CDD:212657"
gene complement(414842..416110)
/gene="araJ"
/locus_tag="ECOK1_0375"
/db_xref="GeneID:12688943"
CDS complement(414842..416110)
/gene="araJ"
/locus_tag="ECOK1_0375"
/note="identified by match to protein family HMM PF07690"
/codon_start=1
/transl_table=11
/product="protein araJ"
/protein_id="YP_006099616.1"
/db_xref="GI:386598110"
/db_xref="GeneID:12688943"
/translation="MASLVVILQSITLLATVIGSRSGGCDGGMKKVILSLALGTFGLG
MAEFGIMGVLTELAHNVGISIPAAGHMISYYALGVVVGAPIIALFSSRYSLKHILLFL
VALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIKPGKVTAAVAGM
VSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDIRDEAKGKLR
EQFHFLRSPAPWLIFAATMFGNAGVFAWFSYVKPYMMFISGFSETAMTFIMMLVGLGM
VLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFFGGMKTTSLIFAFICCAGLFAL
SAPLQILLLQNAKGGELLGAAGGQIAFNLGSAVGAYCGGMMLTLGLAYNYVALPAALL
SFAAMSSLLLYGRYKRQQAADSSVLAKPLG"
misc_feature complement(414881..416026)
/gene="araJ"
/locus_tag="ECOK1_0375"
/note="MFS transport protein AraJ; Provisional; Region:
PRK10091"
/db_xref="CDD:182234"
misc_feature complement(414974..416014)
/gene="araJ"
/locus_tag="ECOK1_0375"
/note="The Major Facilitator Superfamily (MFS) is a large
and diverse group of secondary transporters that includes
uniporters, symporters, and antiporters. MFS proteins
facilitate the transport across cytoplasmic or internal
membranes of a variety of...; Region: MFS; cd06174"
/db_xref="CDD:119392"
misc_feature complement(order(415016..415018,415025..415030,
415037..415042,415049..415054,415082..415084,
415091..415096,415106..415108,415115..415120,
415127..415129,415271..415273,415283..415285,
415292..415294,415304..415306,415316..415318,
415358..415360,415367..415372,415379..415384,
415391..415393,415607..415609,415625..415630,
415637..415642,415676..415678,415685..415690,
415697..415702,415709..415714,415850..415855,
415859..415864,415874..415876,415883..415888,
415895..415897,415946..415951,415955..415963,
415970..415972))
/gene="araJ"
/locus_tag="ECOK1_0375"
/note="putative substrate translocation pore; other site"
/db_xref="CDD:119392"
gene complement(416152..419295)
/gene="sbcC"
/locus_tag="ECOK1_0376"
/db_xref="GeneID:12688944"
CDS complement(416152..419295)
/gene="sbcC"
/locus_tag="ECOK1_0376"
/note="identified by similarity to SP:P13458; match to
protein family HMM PF02463; match to protein family HMM
TIGR00618"
/codon_start=1
/transl_table=11
/product="nuclease SbcCD, C subunit"
/protein_id="YP_006099617.1"
/db_xref="GI:386598111"
/db_xref="GeneID:12688944"
/translation="MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKT
TLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRAR
NQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAA
FLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQV
QSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRLDELQQEGSRRQQALQQALAEEEKA
QPQLAALSLAQPARNLRPHWERIAEYSTALAHTRQQIEEVNTRLQSTMALRASIRHHA
AKQSAELQQQQQSLNAWLQEHDRLRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHA
EQKLNALAAITLTLTADEVASALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQ
NVTLEQTQRNAALNEMRHRYKEKTQQLADVKTICEQETRIKTLEAQRAQLQAGQPCPL
CGSTSHPAVEAYQALEPGVNQARLLTLEKEVKKLGEEGATLRGQLDALTKQLQRDENE
AQSLRQDEQALTQQWQAVTASLNITLQPQDDIQPWLDAQDEHERQLRLLSQRHELQGQ
IAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEESWLATRQQEAQSWQHRQN
ELTALQNRIQQLTPILETLPQSDELPHSEETVALENWRQVHEQCLALHSQQQTLQQQD
VLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQT
LVTQTAETLTQHQQHRPGGLSLTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDA
DNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQL
TRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSH
KTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVK
KINGLGYSKLESAFAMK"
misc_feature complement(416155..419295)
/gene="sbcC"
/locus_tag="ECOK1_0376"
/note="exonuclease subunit SbcC; Provisional; Region:
PRK10246"
/db_xref="CDD:182330"
misc_feature complement(<418810..419295)
/gene="sbcC"
/locus_tag="ECOK1_0376"
/note="P-loop containing Nucleoside Triphosphate
Hydrolases; Region: P-loop_NTPase; cl09099"
/db_xref="CDD:214148"
misc_feature complement(419164..419187)
/gene="sbcC"
/locus_tag="ECOK1_0376"
/note="Walker A/P-loop; other site"
/db_xref="CDD:213179"
misc_feature complement(order(418831..418833,419161..419169,
419173..419178))
/gene="sbcC"
/locus_tag="ECOK1_0376"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:213179"
misc_feature complement(418831..418842)
/gene="sbcC"
/locus_tag="ECOK1_0376"
/note="Q-loop/lid; other site"
/db_xref="CDD:213179"
misc_feature complement(416203..>416463)
/gene="sbcC"
/locus_tag="ECOK1_0376"
/note="P-loop containing Nucleoside Triphosphate
Hydrolases; Region: P-loop_NTPase; cl09099"
/db_xref="CDD:214148"
misc_feature complement(416419..416448)
/gene="sbcC"
/locus_tag="ECOK1_0376"
/note="ABC transporter signature motif; other site"
/db_xref="CDD:213179"
misc_feature complement(416347..416364)
/gene="sbcC"
/locus_tag="ECOK1_0376"
/note="Walker B; other site"
/db_xref="CDD:213179"
misc_feature complement(416329..416340)
/gene="sbcC"
/locus_tag="ECOK1_0376"
/note="D-loop; other site"
/db_xref="CDD:213179"
misc_feature complement(416245..416265)
/gene="sbcC"
/locus_tag="ECOK1_0376"
/note="H-loop/switch region; other site"
/db_xref="CDD:213179"
gene complement(419292..420494)
/gene="sbcD"
/locus_tag="ECOK1_0377"
/db_xref="GeneID:12688945"
CDS complement(419292..420494)
/gene="sbcD"
/locus_tag="ECOK1_0377"
/note="identified by similarity to SP:P0AG76; match to
protein family HMM PF00149; match to protein family HMM
TIGR00619"
/codon_start=1
/transl_table=11
/product="nuclease SbcCD subunit D"
/protein_id="YP_006099618.1"
/db_xref="GI:386598112"
/db_xref="GeneID:12688945"
/translation="MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQAHQVDAII
VAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNT
TVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDY
YQQHYADACKLRGAQPLPIITTGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYI
ALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVT
QPMAVLKGDLASITAQLEQWRDISQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVE
VLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFATTLH
SLAGEHEA"
misc_feature complement(419295..420494)
/gene="sbcD"
/locus_tag="ECOK1_0377"
/note="exonuclease subunit SbcD; Provisional; Region:
PRK10966"
/db_xref="CDD:182871"
misc_feature complement(419754..420491)
/gene="sbcD"
/locus_tag="ECOK1_0377"
/note="Mre11 nuclease, N-terminal metallophosphatase
domain; Region: MPP_Mre11_N; cd00840"
/db_xref="CDD:163616"
misc_feature complement(order(419823..419831,419943..419945,
420243..420248,420351..420353,420465..420467,
420471..420473))
/gene="sbcD"
/locus_tag="ECOK1_0377"
/note="active site"
/db_xref="CDD:163616"
misc_feature complement(order(419823..419825,419829..419831,
419943..419945,420246..420248,420351..420353,
420465..420467,420471..420473))
/gene="sbcD"
/locus_tag="ECOK1_0377"
/note="metal binding site [ion binding]; metal-binding
site"
/db_xref="CDD:163616"
misc_feature complement(order(420096..420101,420228..420233,
420237..420239,420342..420344,420441..420461))
/gene="sbcD"
/locus_tag="ECOK1_0377"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:163616"
misc_feature complement(419367..419675)
/gene="sbcD"
/locus_tag="ECOK1_0377"
/note="Type 5 capsule protein repressor C-terminal domain;
Region: SbcD_C; pfam12320"
/db_xref="CDD:204880"
gene 420480..420611
/locus_tag="ECOK1_0378"
/db_xref="GeneID:12688946"
CDS 420480..420611
/locus_tag="ECOK1_0378"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099619.1"
/db_xref="GI:386598113"
/db_xref="GeneID:12688946"
/translation="MKDAHNGSLAKKHGRDYTQTDVPFAFFCATEINNLKICATSFS"
gene 420684..421373
/gene="phoB"
/locus_tag="ECOK1_0379"
/db_xref="GeneID:12688947"
CDS 420684..421373
/gene="phoB"
/locus_tag="ECOK1_0379"
/note="identified by match to protein family HMM PF00072;
match to protein family HMM PF00486; match to protein
family HMM TIGR02154"
/codon_start=1
/transl_table=11
/product="phosphate regulon transcriptional regulatory
protein PhoB"
/protein_id="YP_006099620.1"
/db_xref="GI:386598114"
/db_xref="GeneID:12688947"
/translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNE
PWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDY
ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEF
KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTV
RGTGYRFSTRF"
misc_feature 420684..421370
/gene="phoB"
/locus_tag="ECOK1_0379"
/note="transcriptional regulator PhoB; Provisional;
Region: PRK10161"
/db_xref="CDD:182277"
misc_feature 420699..421043
/gene="phoB"
/locus_tag="ECOK1_0379"
/note="Signal receiver domain; originally thought to be
unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
recently identified in eukaroytes ETR1 Arabidopsis
thaliana; this domain receives the signal from the sensor
partner in a two-component systems; Region: REC; cd00156"
/db_xref="CDD:238088"
misc_feature order(420708..420713,420840..420842,420864..420866,
420930..420932,420987..420989,420996..421001)
/gene="phoB"
/locus_tag="ECOK1_0379"
/note="active site"
/db_xref="CDD:238088"
misc_feature 420840..420842
/gene="phoB"
/locus_tag="ECOK1_0379"
/note="phosphorylation site [posttranslational
modification]"
/db_xref="CDD:238088"
misc_feature order(420849..420854,420858..420866)
/gene="phoB"
/locus_tag="ECOK1_0379"
/note="intermolecular recognition site; other site"
/db_xref="CDD:238088"
misc_feature 420996..421004
/gene="phoB"
/locus_tag="ECOK1_0379"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:238088"
misc_feature 421077..421358
/gene="phoB"
/locus_tag="ECOK1_0379"
/note="Effector domain of response regulator. Bacteria and
certain eukaryotes like protozoa and higher plants use
two-component signal transduction systems to detect and
respond to changes in the environment. The system consists
of a sensor histidine kinase and...; Region: trans_reg_C;
cd00383"
/db_xref="CDD:238225"
misc_feature order(421149..421151,421206..421211,421263..421265,
421272..421274,421296..421301,421332..421334,
421347..421349)
/gene="phoB"
/locus_tag="ECOK1_0379"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:238225"
gene 421431..422726
/gene="phoR"
/locus_tag="ECOK1_0380"
/db_xref="GeneID:12688948"
CDS 421431..422726
/gene="phoR"
/locus_tag="ECOK1_0380"
/EC_number="2.7.3.-"
/note="identified by similarity to SP:P08400; match to
protein family HMM PF00512; match to protein family HMM
PF00989; match to protein family HMM PF02518; match to
protein family HMM TIGR00229; match to protein family HMM
TIGR02966"
/codon_start=1
/transl_table=11
/product="phosphate regulon sensor protein PhoR"
/protein_id="YP_006099621.1"
/db_xref="GI:386598115"
/db_xref="GeneID:12688948"
/translation="MLERLSWKRLVLELLLCCLPAFILGAFFGYLPWFLLASVTGLLI
WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRD
FSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
LTVLQGYLEMMDEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLLNE
KVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTP
EGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLA
IVKHAVNHHESRLNIESTVGKGTRFSFVIPERLIAKNSD"
misc_feature 421431..422720
/gene="phoR"
/locus_tag="ECOK1_0380"
/note="phosphate regulon sensor protein; Provisional;
Region: phoR; PRK11006"
/db_xref="CDD:182895"
misc_feature 421437..421706
/gene="phoR"
/locus_tag="ECOK1_0380"
/note="Domain of unknown function (DUF3329); Region:
DUF3329; pfam11808"
/db_xref="CDD:204751"
misc_feature 421749..422069
/gene="phoR"
/locus_tag="ECOK1_0380"
/note="PAS domain; PAS motifs appear in archaea,
eubacteria and eukarya. Probably the most surprising
identification of a PAS domain was that in EAG-like
K+-channels. PAS domains have been found to bind ligands,
and to act as sensors for light and oxygen in...; Region:
PAS; cd00130"
/db_xref="CDD:238075"
misc_feature order(421797..421799,421809..421811,421827..421829,
421866..421877,421965..421967,421980..421982)
/gene="phoR"
/locus_tag="ECOK1_0380"
/note="putative active site [active]"
/db_xref="CDD:238075"
misc_feature order(421857..421859,421869..421871,421884..421886,
421893..421898,422004..422006,422010..422012)
/gene="phoR"
/locus_tag="ECOK1_0380"
/note="heme pocket [chemical binding]; other site"
/db_xref="CDD:238075"
misc_feature 422037..422225
/gene="phoR"
/locus_tag="ECOK1_0380"
/note="Histidine Kinase A (dimerization/phosphoacceptor)
domain; Histidine Kinase A dimers are formed through
parallel association of 2 domains creating 4-helix
bundles; usually these domains contain a conserved His
residue and are activated via...; Region: HisKA; cd00082"
/db_xref="CDD:119399"
misc_feature order(422049..422051,422061..422063,422073..422075,
422082..422084,422094..422096,422103..422105,
422154..422156,422166..422168,422175..422177,
422187..422189,422196..422198,422208..422210)
/gene="phoR"
/locus_tag="ECOK1_0380"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:119399"
misc_feature 422067..422069
/gene="phoR"
/locus_tag="ECOK1_0380"
/note="phosphorylation site [posttranslational
modification]"
/db_xref="CDD:119399"
misc_feature 422382..422693
/gene="phoR"
/locus_tag="ECOK1_0380"
/note="Histidine kinase-like ATPases; This family includes
several ATP-binding proteins for example: histidine
kinase, DNA gyrase B, topoisomerases, heat shock protein
HSP90, phytochrome-like ATPases and DNA mismatch repair
proteins; Region: HATPase_c; cd00075"
/db_xref="CDD:238030"
misc_feature order(422400..422402,422412..422414,422421..422423,
422490..422492,422496..422498,422502..422504,
422508..422513,422592..422603,422649..422651,
422655..422657,422670..422675,422679..422681)
/gene="phoR"
/locus_tag="ECOK1_0380"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:238030"
misc_feature 422412..422414
/gene="phoR"
/locus_tag="ECOK1_0380"
/note="Mg2+ binding site [ion binding]; other site"
/db_xref="CDD:238030"
misc_feature order(422502..422504,422508..422510,422592..422594,
422598..422600)
/gene="phoR"
/locus_tag="ECOK1_0380"
/note="G-X-G motif; other site"
/db_xref="CDD:238030"
gene 423133..424452
/gene="brnQ"
/locus_tag="ECOK1_0381"
/db_xref="GeneID:12688949"
CDS 423133..424452
/gene="brnQ"
/locus_tag="ECOK1_0381"
/note="identified by similarity to SP:P37011; match to
protein family HMM PF05525; match to protein family HMM
TIGR00796"
/codon_start=1
/transl_table=11
/product="branched-chain amino acid transport system II
carrier protein"
/protein_id="YP_006099622.1"
/db_xref="GI:386598116"
/db_xref="GeneID:12688949"
/translation="MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
AFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRT
ATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
ILSVAAIIWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFG
GGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLS
QLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAF
SDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH"
misc_feature 423133..424449
/gene="brnQ"
/locus_tag="ECOK1_0381"
/note="branched-chain amino acid transport system 2
carrier protein BrnQ; Provisional; Region: PRK15433"
/db_xref="CDD:185331"
gene 424528..425901
/gene="proY"
/locus_tag="ECOK1_0382"
/db_xref="GeneID:12688950"
CDS 424528..425901
/gene="proY"
/locus_tag="ECOK1_0382"
/note="identified by similarity to SP:P37460; match to
protein family HMM PF00324"
/codon_start=1
/transl_table=11
/product="proline-specific permease ProY"
/protein_id="YP_006099623.1"
/db_xref="GI:386598117"
/db_xref="GeneID:12688950"
/translation="MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
LLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
AIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI
IIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEII
GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQH
MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVT
VLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVK
ALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHD
RQLAENQ"
misc_feature 424528..425892
/gene="proY"
/locus_tag="ECOK1_0382"
/note="putative proline-specific permease; Provisional;
Region: proY; PRK10580"
/db_xref="CDD:182566"
misc_feature 424558..>424950
/gene="proY"
/locus_tag="ECOK1_0382"
/note="Spore germination protein; Region: Spore_permease;
cl17796"
/db_xref="CDD:248350"
gene 426057..427874
/gene="malZ"
/locus_tag="ECOK1_0383"
/db_xref="GeneID:12688951"
CDS 426057..427874
/gene="malZ"
/locus_tag="ECOK1_0383"
/EC_number="3.2.1.20"
/note="identified by similarity to SP:P21517; match to
protein family HMM PF00128"
/codon_start=1
/transl_table=11
/product="maltodextrin glucosidase"
/protein_id="YP_006099624.1"
/db_xref="GI:386598118"
/db_xref="GeneID:12688951"
/translation="MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDN
EEMSVPMHKQRSQPQPGVTAWRAAIELSCGQPRRRYSFKLLWHDRQRWFTPQGFSRMP
PARLEQFAIDVPDIGPQWAADQIFYQIFPDRFARNLPREAEQDHVYYHHAAGQEIILR
DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYR
HVDPQFGGDGALLRLRHNTQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPES
PWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGW
RLDVVHMLGEAGGARNNLQHVAGITEAAKETQPDAYIVGEHFGDARQWLQADVEDAAM
NYRGFTFPLWGFLANTDISYDPQQIDAQTCMVWMDNYRAGLSHQQQLRMFNQLDSHDT
ARFKTLLGRDVARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQD
SALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEV
VLPASPLLNVAQWQRKEGHGQLTDGILALPAISATVWMN"
misc_feature 426057..427847
/gene="malZ"
/locus_tag="ECOK1_0383"
/note="maltodextrin glucosidase; Provisional; Region:
PRK10785"
/db_xref="CDD:182728"
misc_feature 426102..426395
/gene="malZ"
/locus_tag="ECOK1_0383"
/note="N-terminal Early set domain associated with the
catalytic domain of cyclomaltodextrinase and
pullulan-degrading enzymes; Region: E_set_CDase_PDE_N;
cd02857"
/db_xref="CDD:199887"
misc_feature order(426285..426287,426291..426293,426339..426344,
426390..426395)
/gene="malZ"
/locus_tag="ECOK1_0383"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:199887"
misc_feature 426423..427652
/gene="malZ"
/locus_tag="ECOK1_0383"
/note="Alpha amylase catalytic domain found in
cyclomaltodextrinases and related proteins; Region:
AmyAc_CMD; cd11338"
/db_xref="CDD:200477"
misc_feature order(426684..426686,426690..426692,426810..426812,
426951..426953,427065..427070,427176..427178,
427182..427184,427398..427403,427533..427535,
427545..427547)
/gene="malZ"
/locus_tag="ECOK1_0383"
/note="active site"
/db_xref="CDD:200477"
misc_feature order(426957..426959,427074..427091,427122..427124,
427182..427187,427251..427253,427350..427352)
/gene="malZ"
/locus_tag="ECOK1_0383"
/note="homodimer interface [polypeptide binding]; other
site"
/db_xref="CDD:200477"
misc_feature order(427065..427067,427176..427178,427401..427403)
/gene="malZ"
/locus_tag="ECOK1_0383"
/note="catalytic site [active]"
/db_xref="CDD:200477"
gene complement(427879..428460)
/gene="acpH"
/locus_tag="ECOK1_0384"
/db_xref="GeneID:12688952"
CDS complement(427879..428460)
/gene="acpH"
/locus_tag="ECOK1_0384"
/EC_number="3.1.4.14"
/note="identified by match to protein family HMM PF04336"
/codon_start=1
/transl_table=11
/product="acyl carrier protein phosphodiesterase"
/protein_id="YP_006099625.1"
/db_xref="GI:386598119"
/db_xref="GeneID:12688952"
/translation="MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHM
HRRIDVLTDNLPEVREAREWFRNETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFT
CYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQSVLNGMASRRPRLDALR
DSWYDLDAHYDALETRFWQFYPRMMEQASRKAL"
misc_feature complement(427882..428460)
/gene="acpH"
/locus_tag="ECOK1_0384"
/note="acyl carrier protein phosphodiesterase;
Provisional; Region: PRK10045"
/db_xref="CDD:182207"
gene 428679..429749
/gene="queA"
/locus_tag="ECOK1_0385"
/db_xref="GeneID:12688953"
CDS 428679..429749
/gene="queA"
/locus_tag="ECOK1_0385"
/EC_number="5.-.-.-"
/note="identified by match to protein family HMM PF02547;
match to protein family HMM TIGR00113"
/codon_start=1
/transl_table=11
/product="S-adenosylmethionine--tRNA
ribosyltransferase-isomerase"
/protein_id="YP_006099626.1"
/db_xref="GI:386598120"
/db_xref="GeneID:12688953"
/translation="MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFT
DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDEKRILAHIRASKAPK
PGAELLLGDDESINATMTARHGALFEVEFNDDRLVLDILNSIGHIPLPPYIDRPDEDA
DRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVD
TIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPF
FDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRF
FSYGDAMFITYNPQAINERVGE"
misc_feature 428679..429710
/gene="queA"
/locus_tag="ECOK1_0385"
/note="S-adenosylmethionine:tRNA
ribosyltransferase-isomerase; Provisional; Region: queA;
PRK00147"
/db_xref="CDD:178900"
misc_feature 428682..429710
/gene="queA"
/locus_tag="ECOK1_0385"
/note="Queuosine biosynthesis protein; Region:
Queuosine_synth; pfam02547"
/db_xref="CDD:202279"
gene 429804..430931
/gene="tgt"
/locus_tag="ECOK1_0386"
/db_xref="GeneID:12688954"
CDS 429804..430931
/gene="tgt"
/locus_tag="ECOK1_0386"
/EC_number="2.4.2.29"
/note="identified by match to protein family HMM PF01702;
match to protein family HMM TIGR00430; match to protein
family HMM TIGR00449"
/codon_start=1
/transl_table=11
/product="queuine tRNA-ribosyltransferase"
/protein_id="YP_006099627.1"
/db_xref="GI:386598121"
/db_xref="GeneID:12688954"
/translation="MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPE
EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
MSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVG
EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
LFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
LRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD"
misc_feature 429804..430895
/gene="tgt"
/locus_tag="ECOK1_0386"
/note="queuine tRNA-ribosyltransferase; Provisional;
Region: tgt; PRK00112"
/db_xref="CDD:234642"
misc_feature 429810..430913
/gene="tgt"
/locus_tag="ECOK1_0386"
/note="tRNA-guanine family transglycosylase; Region:
tgt_general; TIGR00449"
/db_xref="CDD:129541"
gene 430954..431286
/gene="yajC"
/locus_tag="ECOK1_0387"
/db_xref="GeneID:12688955"
CDS 430954..431286
/gene="yajC"
/locus_tag="ECOK1_0387"
/note="identified by match to protein family HMM PF02699;
match to protein family HMM TIGR00739"
/codon_start=1
/transl_table=11
/product="preprotein translocase subunit YajC"
/protein_id="YP_006099628.1"
/db_xref="GI:386598122"
/db_xref="GeneID:12688955"
/translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVL
PKGTMKAL"
misc_feature 430960..431283
/gene="yajC"
/locus_tag="ECOK1_0387"
/note="preprotein translocase subunit YajC; Validated;
Region: yajC; PRK05585"
/db_xref="CDD:235518"
gene 431314..433161
/gene="secD"
/locus_tag="ECOK1_0388"
/db_xref="GeneID:12688956"
CDS 431314..433161
/gene="secD"
/locus_tag="ECOK1_0388"
/note="identified by match to protein family HMM PF02355;
match to protein family HMM PF07549; match to protein
family HMM TIGR00916; match to protein family HMM
TIGR01129"
/codon_start=1
/transl_table=11
/product="protein-export membrane protein SecD"
/protein_id="YP_006099629.1"
/db_xref="GI:386598123"
/db_xref="GeneID:12688956"
/translation="MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVA
ASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVA
LNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
KGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDAR
LSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGAT
ATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQD
EYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEV
INIANIQSRLGNSFRITGINNPSEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNI
EQGLEACLAGLLVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIA
GIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVII
LYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI"
misc_feature 431317..431622
/gene="secD"
/locus_tag="ECOK1_0388"
/note="SecD export protein N-terminal TM region; Region:
SecD-TM1; pfam13721"
/db_xref="CDD:205896"
misc_feature 431626..433158
/gene="secD"
/locus_tag="ECOK1_0388"
/note="preprotein translocase subunit SecD; Reviewed;
Region: secD; PRK05812"
/db_xref="CDD:180271"
misc_feature 431671..431742
/gene="secD"
/locus_tag="ECOK1_0388"
/note="SecD/SecF GG Motif; Region: Sec_GG; pfam07549"
/db_xref="CDD:116168"
misc_feature 432628..433095
/gene="secD"
/locus_tag="ECOK1_0388"
/note="protein-export membrane protein, SecD/SecF family;
Region: 2A0604s01; TIGR00916"
/db_xref="CDD:162105"
gene 433172..434143
/gene="secF"
/locus_tag="ECOK1_0389"
/db_xref="GeneID:12688957"
CDS 433172..434143
/gene="secF"
/locus_tag="ECOK1_0389"
/note="identified by match to protein family HMM PF02355;
match to protein family HMM PF07549; match to protein
family HMM TIGR00916; match to protein family HMM
TIGR00966"
/codon_start=1
/transl_table=11
/product="protein-export membrane protein SecF"
/protein_id="YP_006099630.1"
/db_xref="GI:386598124"
/db_xref="GeneID:12688957"
/translation="MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVR
GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAE
GETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLT
MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
misc_feature 433211..434089
/gene="secF"
/locus_tag="ECOK1_0389"
/note="preprotein translocase subunit SecF; Reviewed;
Region: secF; PRK13022"
/db_xref="CDD:237275"
misc_feature 433289..433375
/gene="secF"
/locus_tag="ECOK1_0389"
/note="SecD/SecF GG Motif; Region: Sec_GG; pfam07549"
/db_xref="CDD:219463"
misc_feature 433511..434077
/gene="secF"
/locus_tag="ECOK1_0389"
/note="Protein export membrane protein; Region: SecD_SecF;
pfam02355"
/db_xref="CDD:216990"
gene 434273..434620
/locus_tag="ECOK1_0390"
/db_xref="GeneID:12688958"
CDS 434273..434620
/locus_tag="ECOK1_0390"
/note="identified by match to protein family HMM PF01844"
/codon_start=1
/transl_table=11
/product="HNH endonuclease family protein"
/protein_id="YP_006099631.1"
/db_xref="GI:386598125"
/db_xref="GeneID:12688958"
/translation="MAIIPKNYARLESDYREKALKIYPWVCGRCSREFVYSNLRELTV
HHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYN
PFADLKAMMNKKK"
misc_feature 434273..434611
/locus_tag="ECOK1_0390"
/note="hypothetical protein; Provisional; Region:
PRK11295"
/db_xref="CDD:183079"
misc_feature 434351..434497
/locus_tag="ECOK1_0390"
/note="HNH endonuclease; Region: HNH; pfam01844"
/db_xref="CDD:190135"
misc_feature order(434399..434401,434405..434413,434417..434419,
434450..434455,434465..434470,434477..434479,
434489..434491)
/locus_tag="ECOK1_0390"
/note="active site"
/db_xref="CDD:28969"
gene complement(434658..435542)
/gene="tsx"
/locus_tag="ECOK1_0391"
/db_xref="GeneID:12688959"
CDS complement(434658..435542)
/gene="tsx"
/locus_tag="ECOK1_0391"
/note="identified by similarity to SP:P40786; match to
protein family HMM PF03502"
/codon_start=1
/transl_table=11
/product="nucleoside-specific channel-forming protein"
/protein_id="YP_006099632.1"
/db_xref="GI:386598126"
/db_xref="GeneID:12688959"
/translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGS
YHTRFGPQLRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEI
EPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMS
LSMNVYAKYQWQNYGAANENEWDGYRFKVKYFVPITDLWGGQLSYIGFTNFDWGSDLG
DDSGYANNGIKTRTNNSIASSHILALNYDHWHYSVVARYWHNGGQWNDDAELNFGNGN
FNVRSTGWGGYLVVGYNF"
misc_feature complement(434661..435542)
/gene="tsx"
/locus_tag="ECOK1_0391"
/note="nucleoside-specific channel-forming protein Tsx;
Provisional; Region: PRK15106"
/db_xref="CDD:237911"
gene complement(435840..436379)
/locus_tag="ECOK1_0392"
/db_xref="GeneID:12688960"
CDS complement(435840..436379)
/locus_tag="ECOK1_0392"
/codon_start=1
/transl_table=11
/product="putative lipoprotein"
/protein_id="YP_006099633.1"
/db_xref="GI:386598127"
/db_xref="GeneID:12688960"
/translation="MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLN
KETVKITQQNRLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDTDGTTLTLR
IQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKG
MSVDQLGFVRIHDIQPVMQ"
misc_feature complement(435843..436379)
/locus_tag="ECOK1_0392"
/note="hypothetical protein; Provisional; Region:
PRK11530"
/db_xref="CDD:183180"
gene 436530..436979
/gene="nrdR"
/locus_tag="ECOK1_0393"
/db_xref="GeneID:12688961"
CDS 436530..436979
/gene="nrdR"
/locus_tag="ECOK1_0393"
/note="identified by match to protein family HMM PF03477;
match to protein family HMM TIGR00244"
/codon_start=1
/transl_table=11
/product="NrdR family transcriptional regulator"
/protein_id="YP_006099634.1"
/db_xref="GI:386598128"
/db_xref="GeneID:12688961"
/translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVA
ELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGERE
VPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED"
misc_feature 436530..436970
/gene="nrdR"
/locus_tag="ECOK1_0393"
/note="transcriptional regulator NrdR; Validated; Region:
nrdR; PRK00464"
/db_xref="CDD:234774"
misc_feature 436674..436940
/gene="nrdR"
/locus_tag="ECOK1_0393"
/note="ATP cone domain; Region: ATP-cone; pfam03477"
/db_xref="CDD:217585"
gene 436983..438086
/gene="ribD"
/locus_tag="ECOK1_0394"
/db_xref="GeneID:12688962"
CDS 436983..438086
/gene="ribD"
/locus_tag="ECOK1_0394"
/EC_number="3.5.4.26"
/EC_number="1.1.1.193"
/note="identified by similarity to SP:P25539; match to
protein family HMM PF00383; match to protein family HMM
PF01872; match to protein family HMM TIGR00227; match to
protein family HMM TIGR00326"
/codon_start=1
/transl_table=11
/product="riboflavin biosynthesis protein RibD"
/protein_id="YP_006099635.1"
/db_xref="GI:386598129"
/db_xref="GeneID:12688962"
/translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQ
RAGEPHAEVQALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVAAMQD
PNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWSELDEQTQGL
YPQQNLRQPVRIVIDSQNRVTPEHRIVQQPGETWFARTQEDSREWPETVRTLLIPEHK
GHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGNDARGLC
TLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA"
misc_feature 436983..438083
/gene="ribD"
/locus_tag="ECOK1_0394"
/note="bifunctional
diaminohydroxyphosphoribosylaminopyrimidine
deaminase/5-amino-6-(5-phosphoribosylamino)uracil
reductase; Provisional; Region: ribD; PRK10786"
/db_xref="CDD:182729"
misc_feature 437001..437339
/gene="ribD"
/locus_tag="ECOK1_0394"
/note="Riboflavin-specific deaminase. Riboflavin
biosynthesis protein RibD
(Diaminohydroxyphosphoribosylaminopyrimidine deaminase)
catalyzes the deamination of
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone
5'-phosphate, which is an intermediate step in the...;
Region: Riboflavin_deaminase-reductase; cd01284"
/db_xref="CDD:29827"
misc_feature order(437130..437138,437202..437207,437232..437234)
/gene="ribD"
/locus_tag="ECOK1_0394"
/note="catalytic motif [active]"
/db_xref="CDD:29827"
misc_feature order(437130..437132,437136..437138,437205..437207,
437232..437234)
/gene="ribD"
/locus_tag="ECOK1_0394"
/note="Zn binding site [ion binding]; other site"
/db_xref="CDD:29827"
misc_feature 437415..438080
/gene="ribD"
/locus_tag="ECOK1_0394"
/note="riboflavin-specific deaminase C-terminal domain;
Region: ribD_Cterm; TIGR00227"
/db_xref="CDD:129330"
gene 438175..438645
/gene="ribH"
/locus_tag="ECOK1_0395"
/db_xref="GeneID:12688963"
CDS 438175..438645
/gene="ribH"
/locus_tag="ECOK1_0395"
/EC_number="6.3.3.-"
/note="identified by similarity to SP:P61714; match to
protein family HMM PF00885; match to protein family HMM
TIGR00114"
/codon_start=1
/transl_table=11
/product="6,7-dimethyl-8-ribityllumazine synthase"
/protein_id="YP_006099636.1"
/db_xref="GI:386598130"
/db_xref="GeneID:12688963"
/translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQV
KDENITIVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLA
HVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
misc_feature 438217..438618
/gene="ribH"
/locus_tag="ECOK1_0395"
/note="lumazine synthase (6,7-dimethyl-8-ribityllumazine
synthase, LS), catalyzes the penultimate step in the
biosynthesis of riboflavin (vitamin B2); type-I; Region:
Lumazine_synthase-I; cd09209"
/db_xref="CDD:187742"
misc_feature order(438220..438222,438238..438240,438328..438339,
438346..438351,438355..438363,438367..438375,
438379..438381,438391..438393,438424..438426,
438430..438435,438439..438441,438445..438450,
438454..438462,438466..438474,438478..438492,
438499..438504,438514..438516,438520..438522,
438526..438528,438532..438534,438544..438546,
438556..438558,438580..438582,438589..438591,
438601..438603,438610..438615)
/gene="ribH"
/locus_tag="ECOK1_0395"
/note="homopentamer interface [polypeptide binding]; other
site"
/db_xref="CDD:187742"
misc_feature order(438238..438243,438340..438351,438412..438429,
438433..438435,438439..438444,438511..438525,
438556..438558,438580..438582,438589..438591)
/gene="ribH"
/locus_tag="ECOK1_0395"
/note="active site"
/db_xref="CDD:187742"
gene 438665..439084
/gene="nusB"
/locus_tag="ECOK1_0396"
/db_xref="GeneID:12688964"
CDS 438665..439084
/gene="nusB"
/locus_tag="ECOK1_0396"
/note="identified by match to protein family HMM PF01029;
match to protein family HMM TIGR01951"
/codon_start=1
/transl_table=11
/product="transcription termination/antitermination factor
NusB"
/protein_id="YP_006099637.1"
/db_xref="GI:386598131"
/db_xref="GeneID:12688964"
/translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
VLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKV
AINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
misc_feature 438680..439066
/gene="nusB"
/locus_tag="ECOK1_0396"
/note="Transcription termination factor NusB (N
protein-Utilization Substance B). NusB plays a key role in
the regulation of ribosomal RNA biosynthesis in eubacteria
by modulating the efficiency of transcriptional
antitermination. NusB along with other Nus...; Region:
Terminator_NusB; cd00619"
/db_xref="CDD:238342"
misc_feature order(438680..438682,438692..438694)
/gene="nusB"
/locus_tag="ECOK1_0396"
/note="putative RNA binding site [nucleotide binding];
other site"
/db_xref="CDD:238342"
gene 439162..440139
/gene="thiL"
/locus_tag="ECOK1_0397"
/db_xref="GeneID:12688965"
CDS 439162..440139
/gene="thiL"
/locus_tag="ECOK1_0397"
/EC_number="2.7.4.16"
/note="identified by similarity to SP:P77785; match to
protein family HMM PF02769; match to protein family HMM
TIGR01379"
/codon_start=1
/transl_table=11
/product="thiamine-monophosphate kinase"
/protein_id="YP_006099638.1"
/db_xref="GI:386598132"
/db_xref="GeneID:12688965"
/translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAI
STDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLES
FSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGT
PGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLI
SDLGHIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNR
GALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTLDWKGYDHFATP"
misc_feature 439162..440127
/gene="thiL"
/locus_tag="ECOK1_0397"
/note="thiamine monophosphate kinase; Provisional; Region:
PRK05731"
/db_xref="CDD:235583"
misc_feature 439171..440052
/gene="thiL"
/locus_tag="ECOK1_0397"
/note="ThiL (Thiamine-monophosphate kinase) plays a dual
role in de novo biosynthesis and in salvage of exogenous
thiamine. Thiamine salvage occurs in two steps, with
thiamine kinase catalyzing the formation of thiamine
phosphate, and ThiL catalyzing the...; Region: ThiL;
cd02194"
/db_xref="CDD:100030"
misc_feature order(439186..439188,439243..439251,439384..439386,
439423..439425,439471..439473,439519..439527,
439597..439599,439795..439797,439801..439806)
/gene="thiL"
/locus_tag="ECOK1_0397"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:100030"
misc_feature order(439195..439197,439252..439254,439297..439305,
439309..439311,439471..439473,439516..439518,
439525..439536,439552..439554,439558..439560)
/gene="thiL"
/locus_tag="ECOK1_0397"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:100030"
gene 440117..440635
/gene="pgpA"
/locus_tag="ECOK1_0398"
/db_xref="GeneID:12688966"
CDS 440117..440635
/gene="pgpA"
/locus_tag="ECOK1_0398"
/note="identified by match to protein family HMM PF04608"
/codon_start=1
/transl_table=11
/product="phosphatidylglycerophosphatase A"
/protein_id="YP_006099639.1"
/db_xref="GI:386598133"
/db_xref="GeneID:12688966"
/translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLA
AIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
MALPTNDWQWVTAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILY
FIGHHWPLGILS"
misc_feature 440177..440602
/gene="pgpA"
/locus_tag="ECOK1_0398"
/note="Phosphatidylglycerophosphatase A; a bacterial
membrane-associated enzyme involved in lipid metabolism;
Region: PgpA; cd06971"
/db_xref="CDD:133477"
misc_feature order(440186..440188,440252..440254,440303..440305,
440312..440317,440324..440329,440375..440377,
440384..440392,440399..440404,440408..440413,
440420..440422,440453..440461,440465..440473,
440477..440482,440486..440491,440600..440602)
/gene="pgpA"
/locus_tag="ECOK1_0398"
/note="tetramer interfaces [polypeptide binding]; other
site"
/db_xref="CDD:133477"
misc_feature order(440384..440386,440393..440398,440546..440548,
440555..440560)
/gene="pgpA"
/locus_tag="ECOK1_0398"
/note="binuclear metal-binding site [ion binding]; other
site"
/db_xref="CDD:133477"
gene complement(440689..441663)
/locus_tag="ECOK1_0399"
/db_xref="GeneID:12688967"
CDS complement(440689..441663)
/locus_tag="ECOK1_0399"
/note="identified by match to protein family HMM PF00248"
/codon_start=1
/transl_table=11
/product="oxidoreductase, aldo/keto reductase family"
/protein_id="YP_006099640.1"
/db_xref="GI:386598134"
/db_xref="GeneID:12688967"
/translation="MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPII
KRALEGGINFFDTANSYSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSR
AQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGR
LTRPWGETTARLVSDEVGKNLYQESNENDAQIVERLTGVSEELGATRAQVALAWLLSK
PGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPVVGFK"
misc_feature complement(440698..441663)
/locus_tag="ECOK1_0399"
/note="Predicted oxidoreductases (related to aryl-alcohol
dehydrogenases) [Energy production and conversion];
Region: Tas; COG0667"
/db_xref="CDD:31011"
misc_feature complement(440728..441657)
/locus_tag="ECOK1_0399"
/note="Aldo-keto reductases (AKRs) are a superfamily of
soluble NAD(P)(H) oxidoreductases whose chief purpose is
to reduce aldehydes and ketones to primary and secondary
alcohols. AKRs are present in all phyla and are of
importance to both health and industrial...; Region:
Aldo_ket_red; cd06660"
/db_xref="CDD:119408"
misc_feature complement(order(440779..440784,440791..440793,
440806..440817,440866..440868,441016..441033,
441115..441117,441190..441195,441280..441285,
441400..441402,441481..441483,441496..441498,
441601..441609))
/locus_tag="ECOK1_0399"
/note="active site"
/db_xref="CDD:119408"
misc_feature complement(order(441283..441285,441400..441402,
441481..441483,441496..441498))
/locus_tag="ECOK1_0399"
/note="catalytic tetrad [active]"
/db_xref="CDD:119408"
gene complement(441718..443580)
/gene="dxs"
/locus_tag="ECOK1_0400"
/db_xref="GeneID:12688968"
CDS complement(441718..443580)
/gene="dxs"
/locus_tag="ECOK1_0400"
/EC_number="2.2.1.7"
/note="identified by similarity to SP:P77488; match to
protein family HMM PF02779; match to protein family HMM
PF02780; match to protein family HMM TIGR00204"
/codon_start=1
/transl_table=11
/product="1-deoxy-D-xylulose-5-phosphate synthase"
/protein_id="YP_006099641.1"
/db_xref="GI:386598135"
/db_xref="GeneID:12688968"
/translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMA
FEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSG
VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQ
FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAA
KDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIY
STFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAI
LNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAG
SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA"
misc_feature complement(441721..443550)
/gene="dxs"
/locus_tag="ECOK1_0400"
/note="1-deoxy-D-xylulose-5-phosphate synthase; Region:
dxs; TIGR00204"
/db_xref="CDD:129308"
misc_feature complement(442717..443442)
/gene="dxs"
/locus_tag="ECOK1_0400"
/note="Thiamine pyrophosphate (TPP) family, DXS subfamily,
TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate
synthase (DXS) is a regulatory enzyme of the
mevalonate-independent pathway involved in terpenoid
biosynthesis. Terpeniods are plant natural products...;
Region: TPP_DXS; cd02007"
/db_xref="CDD:238965"
misc_feature complement(order(443032..443034,443038..443040,
443119..443130,443212..443214))
/gene="dxs"
/locus_tag="ECOK1_0400"
/note="TPP-binding site; other site"
/db_xref="CDD:238965"
misc_feature complement(442147..442614)
/gene="dxs"
/locus_tag="ECOK1_0400"
/note="Pyrimidine (PYR) binding domain of
1-deoxy-D-xylulose-5-phosphate synthase (DXS),
transketolase (TK), and related proteins; Region:
TPP_PYR_DXS_TK_like; cd07033"
/db_xref="CDD:132916"
misc_feature complement(order(442174..442176,442240..442245,
442291..442293,442300..442302,442375..442380,
442387..442389,442441..442449,442453..442458,
442465..442482,442486..442488,442495..442497,
442546..442548,442564..442566,442570..442572))
/gene="dxs"
/locus_tag="ECOK1_0400"
/note="PYR/PP interface [polypeptide binding]; other site"
/db_xref="CDD:132916"
misc_feature complement(order(442249..442251,442255..442260,
442264..442269,442294..442296,442300..442302,
442381..442383,442387..442392,442471..442479,
442486..442488,442546..442548))
/gene="dxs"
/locus_tag="ECOK1_0400"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:132916"
misc_feature complement(order(442387..442389,442396..442398,
442471..442473,442477..442479))
/gene="dxs"
/locus_tag="ECOK1_0400"
/note="TPP binding site [chemical binding]; other site"
/db_xref="CDD:132916"
misc_feature complement(441748..442098)
/gene="dxs"
/locus_tag="ECOK1_0400"
/note="Transketolase, C-terminal domain; Region:
Transketolase_C; pfam02780"
/db_xref="CDD:217227"
gene complement(443605..444504)
/gene="ispA"
/locus_tag="ECOK1_0401"
/db_xref="GeneID:12688969"
CDS complement(443605..444504)
/gene="ispA"
/locus_tag="ECOK1_0401"
/EC_number="2.5.1.10"
/note="identified by similarity to SP:P22939; match to
protein family HMM PF00348"
/codon_start=1
/transl_table=11
/product="geranyltranstransferase"
/protein_id="YP_006099642.1"
/db_xref="GI:386598136"
/db_xref="GeneID:12688969"
/translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGG
KRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
VKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQAL
DLDAEGKRVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLA
FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQ
LAEQSLDTSALEALADYIIQRNK"
misc_feature complement(443608..444504)
/gene="ispA"
/locus_tag="ECOK1_0401"
/note="Geranylgeranyl pyrophosphate synthase [Coenzyme
metabolism]; Region: IspA; COG0142"
/db_xref="CDD:30491"
misc_feature complement(443614..444420)
/gene="ispA"
/locus_tag="ECOK1_0401"
/note="Trans-Isoprenyl Diphosphate Synthases,
head-to-tail; Region: Trans_IPPS_HT; cd00685"
/db_xref="CDD:173833"
misc_feature complement(order(443764..443766,443779..443781,
443794..443796,443824..443826,443833..443838,
443950..443952,443959..443964,444022..444024,
444031..444033,444217..444222,444241..444246,
444250..444258,444262..444270,444277..444279))
/gene="ispA"
/locus_tag="ECOK1_0401"
/note="substrate binding pocket [chemical binding]; other
site"
/db_xref="CDD:173833"
misc_feature complement(444241..444270)
/gene="ispA"
/locus_tag="ECOK1_0401"
/note="chain length determination region; other site"
/db_xref="CDD:173833"
misc_feature complement(order(443764..443766,443779..443781,
443794..443796,443824..443826,443833..443838,
443962..443964,444022..444024,444217..444222,
444241..444243,444250..444255))
/gene="ispA"
/locus_tag="ECOK1_0401"
/note="substrate-Mg2+ binding site; other site"
/db_xref="CDD:173833"
misc_feature complement(order(443833..443838,443962..443964,
444217..444222,444241..444243,444250..444255))
/gene="ispA"
/locus_tag="ECOK1_0401"
/note="catalytic residues [active]"
/db_xref="CDD:173833"
misc_feature complement(order(443962..443964,444022..444024,
444217..444222,444241..444243,444250..444255))
/gene="ispA"
/locus_tag="ECOK1_0401"
/note="aspartate-rich region 1; other site"
/db_xref="CDD:173833"
misc_feature complement(order(443758..443772,443779..443796,
443812..443817,444187..444225,444232..444237))
/gene="ispA"
/locus_tag="ECOK1_0401"
/note="active site lid residues [active]"
/db_xref="CDD:173833"
misc_feature complement(order(443764..443766,443779..443781,
443794..443796,443824..443826,443833..443838))
/gene="ispA"
/locus_tag="ECOK1_0401"
/note="aspartate-rich region 2; other site"
/db_xref="CDD:173833"
gene complement(444504..444746)
/gene="xseB"
/locus_tag="ECOK1_0402"
/db_xref="GeneID:12688970"
CDS complement(444504..444746)
/gene="xseB"
/locus_tag="ECOK1_0402"
/EC_number="3.1.11.6"
/note="identified by similarity to SP:P0A8H2; match to
protein family HMM PF02609; match to protein family HMM
TIGR01280"
/codon_start=1
/transl_table=11
/product="exodeoxyribonuclease VII small subunit"
/protein_id="YP_006099643.1"
/db_xref="GI:386598137"
/db_xref="GeneID:12688970"
/translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQ
LARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
misc_feature complement(444513..444746)
/gene="xseB"
/locus_tag="ECOK1_0402"
/note="exodeoxyribonuclease VII small subunit;
Provisional; Region: PRK00977"
/db_xref="CDD:179195"
gene 444952..446400
/gene="thiI"
/locus_tag="ECOK1_0403"
/db_xref="GeneID:12688971"
CDS 444952..446400
/gene="thiI"
/locus_tag="ECOK1_0403"
/note="identified by similarity to SP:P77718; match to
protein family HMM PF02568; match to protein family HMM
PF02926; match to protein family HMM TIGR00342"
/codon_start=1
/transl_table=11
/product="thiamine biosynthesis/tRNA modification protein
ThiI"
/protein_id="YP_006099644.1"
/db_xref="GI:386598138"
/db_xref="GeneID:12688971"
/translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
RHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQL
EGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPEVTVHLEVEDDRLL
LIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEI
GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVA
ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
DFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTE
QEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQSK
TWLLWCERGVMSRLQALYLREQGFNNVKVYRP"
misc_feature 444952..446397
/gene="thiI"
/locus_tag="ECOK1_0403"
/note="tRNA s(4)U8 sulfurtransferase; Provisional; Region:
PRK01269"
/db_xref="CDD:234932"
misc_feature 444955..445461
/gene="thiI"
/locus_tag="ECOK1_0403"
/note="THUMP domain of thiamine biosynthesis protein ThiI;
Region: THUMP_ThiI; cd11716"
/db_xref="CDD:212585"
misc_feature 445489..446010
/gene="thiI"
/locus_tag="ECOK1_0403"
/note="ThiI is required for thiazole synthesis in the
thiamine biosynthesis pathway. It belongs to the Adenosine
Nucleotide Hydrolysis suoerfamily and predicted to bind to
Adenosine nucleotide; Region: ThiI; cd01712"
/db_xref="CDD:238845"
misc_feature order(445498..445506,445510..445521,445576..445578,
445582..445584)
/gene="thiI"
/locus_tag="ECOK1_0403"
/note="Ligand Binding Site [chemical binding]; other site"
/db_xref="CDD:238845"
misc_feature 446164..446394
/gene="thiI"
/locus_tag="ECOK1_0403"
/note="Rhodanese Homology Domain (RHOD); an alpha beta
fold domain found duplicated in the rhodanese protein. The
cysteine containing enzymatically active version of the
domain is also found in the Cdc25 class of protein
phosphatases and a variety of proteins...; Region: RHOD;
cd00158"
/db_xref="CDD:238089"
misc_feature 446317..446319
/gene="thiI"
/locus_tag="ECOK1_0403"
/note="active site residue [active]"
/db_xref="CDD:238089"
gene complement(446454..447044)
/gene="thiJ"
/locus_tag="ECOK1_0404"
/db_xref="GeneID:12688972"
CDS complement(446454..447044)
/gene="thiJ"
/locus_tag="ECOK1_0404"
/note="identified by match to protein family HMM PF01965;
match to protein family HMM TIGR01383"
/codon_start=1
/transl_table=11
/product="protein ThiJ"
/protein_id="YP_006099645.1"
/db_xref="GI:386598139"
/db_xref="GeneID:12688972"
/translation="MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLA
ITCSRGVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIV
AAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWQDKRVVWDARVKLLTSQGPGT
AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
misc_feature complement(446457..447044)
/gene="thiJ"
/locus_tag="ECOK1_0404"
/note="oxidative-stress-resistance chaperone; Provisional;
Region: PRK11574"
/db_xref="CDD:183210"
misc_feature complement(446529..447032)
/gene="thiJ"
/locus_tag="ECOK1_0404"
/note="Type 1 glutamine amidotransferase (GATase1)-like
domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135"
/db_xref="CDD:153229"
misc_feature complement(446727..446729)
/gene="thiJ"
/locus_tag="ECOK1_0404"
/note="conserved cys residue [active]"
/db_xref="CDD:153229"
gene complement(447007..447918)
/gene="panE"
/locus_tag="ECOK1_0405"
/db_xref="GeneID:12688973"
CDS complement(447007..447918)
/gene="panE"
/locus_tag="ECOK1_0405"
/EC_number="1.1.1.169"
/note="identified by match to protein family HMM PF02558;
match to protein family HMM PF08546; match to protein
family HMM TIGR00745"
/codon_start=1
/transl_table=11
/product="2-dehydropantoate 2-reductase"
/protein_id="YP_006099646.1"
/db_xref="GI:386598140"
/db_xref="GeneID:12688973"
/translation="MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVET
DGSIFNESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGT
IEELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVL
PDVAWHNNIRAELWRKLAVNCVINPLTATWNCPNGELRHHPQEIMQICEEVAAVIERE
GHHTSAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVP
ENTRLFEMVKRKESEYERIGTGLPRPW"
misc_feature complement(447034..447918)
/gene="panE"
/locus_tag="ECOK1_0405"
/note="2-dehydropantoate 2-reductase; Reviewed; Region:
PRK06522"
/db_xref="CDD:180603"
misc_feature complement(447487..447912)
/gene="panE"
/locus_tag="ECOK1_0405"
/note="Ketopantoate reductase PanE/ApbA; Region: ApbA;
pfam02558"
/db_xref="CDD:202282"
misc_feature complement(447052..447417)
/gene="panE"
/locus_tag="ECOK1_0405"
/note="Ketopantoate reductase PanE/ApbA C terminal;
Region: ApbA_C; pfam08546"
/db_xref="CDD:203977"
gene 448086..448577
/locus_tag="ECOK1_0406"
/db_xref="GeneID:12688974"
CDS 448086..448577
/locus_tag="ECOK1_0406"
/note="identified by similarity to SP:P59561; match to
protein family HMM PF04461"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099647.1"
/db_xref="GI:386598141"
/db_xref="GeneID:12688974"
/translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDA
SKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGI
ESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKN
FRD"
misc_feature 448086..448574
/locus_tag="ECOK1_0406"
/note="Uncharacterized protein conserved in bacteria
[Function unknown]; Region: COG1666"
/db_xref="CDD:224580"
misc_feature 448089..448571
/locus_tag="ECOK1_0406"
/note="Proteins similar to Escherichia coli YajQ; Region:
YajQ_like; cd11740"
/db_xref="CDD:213038"
gene complement(448705..450069)
/locus_tag="ECOK1_0407"
/db_xref="GeneID:12688975"
CDS complement(448705..450069)
/locus_tag="ECOK1_0407"
/note="identified by match to protein family HMM PF07690"
/codon_start=1
/transl_table=11
/product="major facilitator family transporter"
/protein_id="YP_006099648.1"
/db_xref="GI:386598142"
/db_xref="GeneID:12688975"
/translation="MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
ASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIW
GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITH
KLGLHVLFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLN
FGIMCLHILLMSTFVALPGQLADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRK
MKQVFVFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAG
YKGTAMGVYSTSQFLGVAIGGSLGGWIDGMFDGQGVFLAGAMLAAVWLAVASTMKEPP
YVSSLRIEIPANIAANEALKVRLLETEGIKEVLIAEEEHSAYVKIDSKVTNRFEVEQA
IRQA"
misc_feature complement(448915..450030)
/locus_tag="ECOK1_0407"
/note="The Major Facilitator Superfamily (MFS) is a large
and diverse group of secondary transporters that includes
uniporters, symporters, and antiporters. MFS proteins
facilitate the transport across cytoplasmic or internal
membranes of a variety of...; Region: MFS; cd06174"
/db_xref="CDD:119392"
misc_feature complement(449005..450021)
/locus_tag="ECOK1_0407"
/note="Major Facilitator Superfamily; Region: MFS_1;
pfam07690"
/db_xref="CDD:191813"
misc_feature complement(order(449017..449019,449026..449031,
449038..449043,449050..449055,449086..449088,
449095..449100,449110..449112,449119..449124,
449131..449133,449275..449277,449287..449289,
449296..449298,449308..449310,449320..449322,
449362..449364,449371..449376,449383..449388,
449395..449397,449626..449628,449644..449649,
449656..449661,449695..449697,449704..449709,
449716..449721,449728..449733,449863..449868,
449872..449877,449887..449889,449896..449901,
449908..449910,449962..449967,449971..449979,
449986..449988))
/locus_tag="ECOK1_0407"
/note="putative substrate translocation pore; other site"
/db_xref="CDD:119392"
gene complement(450218..451108)
/gene="cyoE"
/locus_tag="ECOK1_0408"
/db_xref="GeneID:12688976"
CDS complement(450218..451108)
/gene="cyoE"
/locus_tag="ECOK1_0408"
/EC_number="2.5.1.-"
/note="identified by match to protein family HMM PF01040;
match to protein family HMM TIGR01473"
/codon_start=1
/transl_table=11
/product="protoheme IX farnesyltransferase"
/protein_id="YP_006099649.1"
/db_xref="GI:386598143"
/db_xref="GeneID:12688976"
/translation="MIFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLW
FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDS
GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAV
ATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALS
VMMSVDFMVPDSHTLLAAVW"
misc_feature complement(450221..451108)
/gene="cyoE"
/locus_tag="ECOK1_0408"
/note="protoheme IX farnesyltransferase; Provisional;
Region: PRK13362"
/db_xref="CDD:184001"
misc_feature complement(450293..451054)
/gene="cyoE"
/locus_tag="ECOK1_0408"
/note="UbiA prenyltransferase family; Region: UbiA;
pfam01040"
/db_xref="CDD:216260"
gene complement(451120..451449)
/gene="cyoD"
/locus_tag="ECOK1_0409"
/db_xref="GeneID:12688977"
CDS complement(451120..451449)
/gene="cyoD"
/locus_tag="ECOK1_0409"
/EC_number="1.10.3.-"
/note="identified by similarity to SP:P0ABJ6; match to
protein family HMM PF03626; match to protein family HMM
TIGR02847"
/codon_start=1
/transl_table=11
/product="cytochrome o ubiquinol oxidase subunit IV"
/protein_id="YP_006099650.1"
/db_xref="GI:386598144"
/db_xref="GeneID:12688977"
/translation="MSHSNASSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPA
VILGTILAMAVVQILVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNL
NYNMMMH"
misc_feature complement(451123..451407)
/gene="cyoD"
/locus_tag="ECOK1_0409"
/note="cytochrome o ubiquinol oxidase subunit IV;
Provisional; Region: PRK10582"
/db_xref="CDD:182568"
gene complement(451449..452063)
/gene="cyoC"
/locus_tag="ECOK1_0410"
/db_xref="GeneID:12688978"
CDS complement(451449..452063)
/gene="cyoC"
/locus_tag="ECOK1_0410"
/EC_number="1.10.3.-"
/note="identified by similarity to SP:P0ABJ3; match to
protein family HMM PF00510; match to protein family HMM
TIGR02842"
/codon_start=1
/transl_table=11
/product="cytochrome o ubiquinol oxidase subunit III"
/protein_id="YP_006099651.1"
/db_xref="GI:386598145"
/db_xref="GeneID:12688978"
/translation="MATDTLTHATAHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILF
ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVVSWL
ALTWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
MVQIARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
misc_feature complement(451458..451991)
/gene="cyoC"
/locus_tag="ECOK1_0410"
/note="Ubiquinol oxidase subunit III subfamily. Ubiquinol
oxidase, the terminal oxidase in the respiratory chains of
aerobic bacteria, is a multi-chain transmembrane protein
located in the cell membrane. It catalyzes the reduction
of O2 and simultaneously...; Region:
Ubiquinol_oxidase_III; cd02863"
/db_xref="CDD:29487"
misc_feature complement(order(451926..451928,451935..451940,
451947..451952,451971..451973,451980..451982))
/gene="cyoC"
/locus_tag="ECOK1_0410"
/note="Subunit I/III interface [polypeptide binding];
other site"
/db_xref="CDD:29487"
misc_feature complement(order(451509..451511,451530..451532,
451815..451820,451830..451832,451839..451841,
451950..451952,451974..451976))
/gene="cyoC"
/locus_tag="ECOK1_0410"
/note="Subunit III/IV interface [polypeptide binding];
other site"
/db_xref="CDD:29487"
gene complement(452053..454044)
/gene="cyoB"
/locus_tag="ECOK1_0411"
/db_xref="GeneID:12688979"
CDS complement(452053..454044)
/gene="cyoB"
/locus_tag="ECOK1_0411"
/EC_number="1.10.3.-"
/note="identified by match to protein family HMM PF00115;
match to protein family HMM TIGR02843"
/codon_start=1
/transl_table=11
/product="cytochrome o ubiquinol oxidase subunit I"
/protein_id="YP_006099652.1"
/db_xref="GI:386598146"
/db_xref="GeneID:12688979"
/translation="MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYL
WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL
GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP
GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFS
VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
TWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALG
ILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWE
MKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIIT
WIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN"
misc_feature complement(452221..453933)
/gene="cyoB"
/locus_tag="ECOK1_0411"
/note="Heme/copper-type cytochrome/quinol oxidases,
subunit 1 [Energy production and conversion]; Region:
CyoB; COG0843"
/db_xref="CDD:223913"
misc_feature complement(452389..453903)
/gene="cyoB"
/locus_tag="ECOK1_0411"
/note="Ubiquinol oxidase subunit I. Ubiquinol oxidase,
the terminal oxidase in the respiratory chains of aerobic
bacteria, is a multi-chain transmembrane protein located
in the cell membrane. It catalyzes the reduction of O2
and simultaneously pumps protons...; Region:
Ubiquinol_Oxidase_I; cd01662"
/db_xref="CDD:238832"
misc_feature complement(order(453412..453414,453424..453426,
453442..453447,453610..453612,453619..453621,
453640..453642,453670..453672,453862..453864))
/gene="cyoB"
/locus_tag="ECOK1_0411"
/note="D-pathway; other site"
/db_xref="CDD:238832"
misc_feature complement(order(453736..453744,453751..453753,
453808..453813,453820..453822,453832..453834))
/gene="cyoB"
/locus_tag="ECOK1_0411"
/note="Putative ubiquinol binding site [chemical binding];
other site"
/db_xref="CDD:238832"
misc_feature complement(order(452530..452532,452644..452646,
452770..452772,452782..452784,453727..453729))
/gene="cyoB"
/locus_tag="ECOK1_0411"
/note="Low-spin heme (heme b) binding site [chemical
binding]; other site"
/db_xref="CDD:238832"
misc_feature complement(order(452602..452604,452809..452814,
452824..452826,453214..453219,453232..453234))
/gene="cyoB"
/locus_tag="ECOK1_0411"
/note="Putative water exit pathway; other site"
/db_xref="CDD:238832"
misc_feature complement(order(452788..452790,453043..453048,
453193..453195))
/gene="cyoB"
/locus_tag="ECOK1_0411"
/note="Binuclear center (heme o3/CuB) [ion binding]; other
site"
/db_xref="CDD:238832"
misc_feature complement(order(452959..452961,452968..452970,
453043..453048,453148..453150,453181..453183,
453193..453195))
/gene="cyoB"
/locus_tag="ECOK1_0411"
/note="K-pathway; other site"
/db_xref="CDD:238832"
misc_feature complement(order(452599..452604,452809..452814,
453043..453045))
/gene="cyoB"
/locus_tag="ECOK1_0411"
/note="Putative proton exit pathway; other site"
/db_xref="CDD:238832"
gene complement(454066..455013)
/gene="cyoA"
/locus_tag="ECOK1_0412"
/db_xref="GeneID:12688980"
CDS complement(454066..455013)
/gene="cyoA"
/locus_tag="ECOK1_0412"
/EC_number="1.10.3.-"
/note="identified by similarity to SP:P0ABJ1; match to
protein family HMM PF00116; match to protein family HMM
PF06481; match to protein family HMM TIGR01433"
/codon_start=1
/transl_table=11
/product="cytochrome o ubiquinol oxidase subunit II"
/protein_id="YP_006099653.1"
/db_xref="GI:386598147"
/db_xref="GeneID:12688980"
/translation="MRLRKYNKSLGWLSLFAGTVLLSGCNSALLDPKGQIGLEQRSLI
LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIAAVNEIAFPANTP
VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
KFKAIATPDRAAFDQWVAKAKQSPNTMSDMATFEKLAAPSEYNQVEYFSNVKPDLFAD
VINKFMAHGKSMDMTQPEGEHSAHEGMEGMDMSHAESAH"
misc_feature complement(454069..455013)
/gene="cyoA"
/locus_tag="ECOK1_0412"
/note="cytochrome o ubiquinol oxidase subunit II;
Provisional; Region: PRK10525"
/db_xref="CDD:182518"
misc_feature complement(454339..>454563)
/gene="cyoA"
/locus_tag="ECOK1_0412"
/note="Cytochrome C oxidase subunit II, periplasmic
domain; Region: COX2; cl11412"
/db_xref="CDD:209309"
misc_feature complement(454156..454299)
/gene="cyoA"
/locus_tag="ECOK1_0412"
/note="COX Aromatic Rich Motif; Region: COX_ARM;
pfam06481"
/db_xref="CDD:203465"
gene complement(455472..456947)
/gene="ampG"
/locus_tag="ECOK1_0413"
/db_xref="GeneID:12688981"
CDS complement(455472..456947)
/gene="ampG"
/locus_tag="ECOK1_0413"
/note="identified by match to protein family HMM PF07690;
match to protein family HMM TIGR00901"
/codon_start=1
/transl_table=11
/product="AmpG protein"
/protein_id="YP_006099654.1"
/db_xref="GI:386598148"
/db_xref="GeneID:12688981"
/translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLE
PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
GLALWLADKWLGWQGMYWLMAALLIPCIIATLLAPEPTDTIPVPKTLEQAVVAPLRDF
FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGT
SAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAA
VPGLILLLVCRQTLEYTRVNGNFISRTEYPAGYAFAMWTLAAGISLLAVWLLLLTMDA
LDLTHFSFLPALLEVGVLVALSGVVLGGLLDYLALRKTHLT"
misc_feature complement(455727..456905)
/gene="ampG"
/locus_tag="ECOK1_0413"
/note="muropeptide transporter; Reviewed; Region: ampG;
PRK11902"
/db_xref="CDD:183369"
misc_feature complement(455739..456905)
/gene="ampG"
/locus_tag="ECOK1_0413"
/note="The Major Facilitator Superfamily (MFS) is a large
and diverse group of secondary transporters that includes
uniporters, symporters, and antiporters. MFS proteins
facilitate the transport across cytoplasmic or internal
membranes of a variety of...; Region: MFS; cd06174"
/db_xref="CDD:119392"
misc_feature complement(order(455853..455855,455862..455867,
455874..455879,455886..455891,455922..455924,
455931..455936,455946..455948,455955..455960,
455967..455969,456120..456122,456132..456134,
456141..456143,456156..456158,456168..456170,
456210..456212,456219..456224,456231..456236,
456243..456245,456480..456482,456498..456503,
456510..456515,456549..456551,456558..456563,
456570..456575,456582..456587,456750..456755,
456759..456764,456777..456782,456789..456791,
456840..456845,456849..456857,456864..456866))
/gene="ampG"
/locus_tag="ECOK1_0413"
/note="putative substrate translocation pore; other site"
/db_xref="CDD:119392"
gene complement(456991..457569)
/locus_tag="ECOK1_0414"
/db_xref="GeneID:12688982"
CDS complement(456991..457569)
/locus_tag="ECOK1_0414"
/note="identified by match to protein family HMM PF03923"
/codon_start=1
/transl_table=11
/product="putative lipoprotein"
/protein_id="YP_006099655.1"
/db_xref="GI:386598149"
/db_xref="GeneID:12688982"
/translation="MFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQDPSLMGVT
VSINGADQRTDQALAKVTRDNQIVTLTASRDLRFLLQEVLEKQMTARGYMVGPNGPVN
LQIIVSQLYADVSQGNVRYNIATKADIAIIATAQNGNKMTKNYRASYNVEGAFQASNK
NIADAVNSVLTDTIADMSQDTSIHEFIKQNAR"
misc_feature complement(456994..457569)
/locus_tag="ECOK1_0414"
/note="hypothetical protein; Provisional; Region:
PRK11627"
/db_xref="CDD:183242"
misc_feature complement(457006..457485)
/locus_tag="ECOK1_0414"
/note="Uncharacterized lipoprotein; Region:
Lipoprotein_16; pfam03923"
/db_xref="CDD:217795"
gene complement(457631..457750)
/locus_tag="ECOK1_0415"
/db_xref="GeneID:12688983"
CDS complement(457631..457750)
/locus_tag="ECOK1_0415"
/note="identified by glimmer; putative"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099656.1"
/db_xref="GI:386598150"
/db_xref="GeneID:12688983"
/translation="MKFTDLKIETQASHQRFFYQGRLFRQHDEFTCLTHFPSP"
gene 457874..458191
/locus_tag="ECOK1_0416"
/db_xref="GeneID:12688984"
CDS 457874..458191
/locus_tag="ECOK1_0416"
/note="identified by match to protein family HMM PF01722"
/codon_start=1
/transl_table=11
/product="protein BolA"
/protein_id="YP_006099657.1"
/db_xref="GI:386598151"
/db_xref="GeneID:12688984"
/translation="MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLV
SDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAG
SIA"
misc_feature 457874..458188
/locus_tag="ECOK1_0416"
/note="transcriptional regulator BolA; Provisional;
Region: PRK11628"
/db_xref="CDD:183243"
gene 458200..458388
/locus_tag="ECOK1_0417"
/db_xref="GeneID:12688985"
CDS 458200..458388
/locus_tag="ECOK1_0417"
/codon_start=1
/transl_table=11
/product="hypothetical protein"
/protein_id="YP_006099658.1"
/db_xref="GI:386598152"
/db_xref="GeneID:12688985"
/translation="MQLSALFQYVAKDFMKNGLRAVLFCLDFALFAQHSDENRPGIVK
KYATARNNRSRLIKVMPL"
gene 458535..459824
/gene="tig"
/locus_tag="ECOK1_0418"
/db_xref="GeneID:12688986"
CDS 458535..459824
/gene="tig"
/locus_tag="ECOK1_0418"
/EC_number="5.2.1.8"
/note="identified by match to protein family HMM PF00254;
match to protein family HMM PF05697; match to protein
family HMM PF05698; match to protein family HMM TIGR00115"
/codon_start=1
/transl_table=11
/product="trigger factor"
/protein_id="YP_006099659.1"
/db_xref="GI:386598153"
/db_xref="GeneID:12688986"
/translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGED
FTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEA
EDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP
EEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMER
ELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPR
ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
ELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMN"
misc_feature 458535..459821
/gene="tig"
/locus_tag="ECOK1_0418"
/note="trigger factor; Provisional; Region: tig; PRK01490"
/db_xref="CDD:179299"
misc_feature 458994..459248
/gene="tig"
/locus_tag="ECOK1_0418"
/note="FKBP-type peptidyl-prolyl cis-trans isomerase;
Region: FKBP_C; pfam00254"
/db_xref="CDD:201116"
misc_feature 459318..459719
/gene="tig"
/locus_tag="ECOK1_0418"
/note="Bacterial trigger factor protein (TF) C-terminus;
Region: Trigger_C; pfam05698"
/db_xref="CDD:203309"
gene 460079..460702
/gene="clpP"
/locus_tag="ECOK1_0419"
/db_xref="GeneID:12688987"
CDS 460079..460702
/gene="clpP"
/locus_tag="ECOK1_0419"
/EC_number="3.4.21.92"
/note="identified by match to protein family HMM PF00574;
match to protein family HMM TIGR00493"
/codon_start=1
/transl_table=11
/product="ATP-dependent Clp protease, proteolytic subunit
ClpP"
/protein_id="YP_006099660.1"
/db_xref="GI:386598154"
/db_xref="GeneID:12688987"
/translation="MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
misc_feature 460118..460699
/gene="clpP"
/locus_tag="ECOK1_0419"
/note="Protease subunit of ATP-dependent Clp proteases
[Posttranslational modification, protein turnover,
chaperones / Intracellular trafficking and secretion];
Region: ClpP; COG0740"
/db_xref="CDD:223811"
misc_feature 460172..460684
/gene="clpP"
/locus_tag="ECOK1_0419"
/note="Caseinolytic protease (ClpP) is an ATP-dependent,
highly conserved serine protease; Region: S14_ClpP_2;
cd07017"
/db_xref="CDD:132928"
misc_feature order(460208..460210,460214..460216,460241..460246,
460253..460258,460265..460267,460310..460312,
460331..460333,460343..460345,460352..460354,
460361..460366,460376..460378,460400..460402,
460466..460468,460472..460474,460490..460501,
460541..460543,460550..460552,460556..460558,
460562..460564,460631..460633,460637..460639)
/gene="clpP"
/locus_tag="ECOK1_0419"
/note="oligomer interface [polypeptide binding]; other
site"
/db_xref="CDD:132928"
misc_feature order(460409..460411,460484..460486,460631..460633)
/gene="clpP"
/locus_tag="ECOK1_0419"
/note="active site residues [active]"
/db_xref="CDD:132928"
gene 460828..462102
/gene="clpX"
/locus_tag="ECOK1_0420"
/db_xref="GeneID:12688988"
CDS 460828..462102
/gene="clpX"
/locus_tag="ECOK1_0420"
/note="identified by match to protein family HMM PF00004;
match to protein family HMM PF06689; match to protein
family HMM PF07724; match to protein family HMM TIGR00382"
/codon_start=1
/transl_table=11
/product="ATP-dependent Clp protease ATP-binding subunit
ClpX"
/protein_id="YP_006099661.1"
/db_xref="GI:386598155"
/db_xref="GeneID:12688988"
/translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
NDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
DTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKA
KSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALT
KQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMED
VEKVVIDESVIDGQSKPLLIYGKPEAQQASGE"
misc_feature 460837..462078
/gene="clpX"
/locus_tag="ECOK1_0420"
/note="ATP-dependent protease ATP-binding subunit ClpX;
Provisional; Region: clpX; PRK05342"
/db_xref="CDD:235422"
misc_feature 460864..460980
/gene="clpX"
/locus_tag="ECOK1_0420"
/note="ClpX C4-type zinc finger; Region: zf-C4_ClpX;
pfam06689"
/db_xref="CDD:203502"
misc_feature 461062..>461412
/gene="clpX"
/locus_tag="ECOK1_0420"
/note="The AAA+ (ATPases Associated with a wide variety of
cellular Activities) superfamily represents an ancient
group of ATPases belonging to the ASCE (for additional
strand, catalytic E) division of the P-loop NTPase fold.
The ASCE division also includes ABC; Region: AAA; cd00009"
/db_xref="CDD:99707"
misc_feature 461182..461205
/gene="clpX"
/locus_tag="ECOK1_0420"
/note="Walker A motif; other site"
/db_xref="CDD:99707"
misc_feature order(461185..461208,461377..461379)
/gene="clpX"
/locus_tag="ECOK1_0420"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:99707"
misc_feature 461365..461382
/gene="clpX"
/locus_tag="ECOK1_0420"
/note="Walker B motif; other site"
/db_xref="CDD:99707"
misc_feature 461776..462027
/gene="clpX"
/locus_tag="ECOK1_0420"
/note="C-terminal, D2-small domain, of ClpB protein;
Region: ClpB_D2-small; smart01086"
/db_xref="CDD:198154"
gene 462290..464644
/gene="lon"
/locus_tag="ECOK1_0421"
/db_xref="GeneID:12688989"
CDS 462290..464644
/gene="lon"
/locus_tag="ECOK1_0421"
/EC_number="3.4.21.53"
/note="identified by match to protein family HMM PF00004;
match to protein family HMM PF02190; match to protein
family HMM PF05362; match to protein family HMM PF07728;
match to protein family HMM TIGR00763"
/codon_start=1
/transl_table=11
/product="ATP-dependent protease La"
/protein_id="YP_006099662.1"
/db_xref="GI:386598156"
/db_xref="GeneID:12688989"
/translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
LSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRI
LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLK
HIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
misc_feature 462290..464641
/gene="lon"
/locus_tag="ECOK1_0421"
/note="DNA-binding ATP-dependent protease La; Provisional;
Region: PRK10787"
/db_xref="CDD:182730"
misc_feature 462317..>462475
/gene="lon"
/locus_tag="ECOK1_0421"
/note="Found in ATP-dependent protease La (LON); Region:
LON; smart00464"
/db_xref="CDD:197740"
misc_feature <462767..462871
/gene="lon"
/locus_tag="ECOK1_0421"
/note="Found in ATP-dependent protease La (LON); Region:
LON; smart00464"
/db_xref="CDD:197740"
misc_feature 463280..463753
/gene="lon"
/locus_tag="ECOK1_0421"
/note="The AAA+ (ATPases Associated with a wide variety of
cellular Activities) superfamily represents an ancient
group of ATPases belonging to the ASCE (for additional
strand, catalytic E) division of the P-loop NTPase fold.
The ASCE division also includes ABC; Region: AAA; cd00009"
/db_xref="CDD:99707"
misc_feature 463355..463378
/gene="lon"
/locus_tag="ECOK1_0421"
/note="Walker A motif; other site"
/db_xref="CDD:99707"
misc_feature order(463358..463381,463556..463558,463706..463708)
/gene="lon"
/locus_tag="ECOK1_0421"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:99707"
misc_feature 463544..463561
/gene="lon"
/locus_tag="ECOK1_0421"
/note="Walker B motif; other site"
/db_xref="CDD:99707"
misc_feature 463739..463741
/gene="lon"
/locus_tag="ECOK1_0421"
/note="arginine finger; other site"
/db_xref="CDD:99707"
misc_feature 463997..464602
/gene="lon"
/locus_tag="ECOK1_0421"
/note="Lon protease (S16) C-terminal proteolytic domain;
Region: Lon_C; pfam05362"
/db_xref="CDD:191262"
STS 462510..463610
/gene="lon"
/locus_tag="ECOK1_0421"
/standard_name="D14S161"
/db_xref="UniSTS:148385"
gene 464853..465125
/gene="hupB"
/locus_tag="ECOK1_0422"
/db_xref="GeneID:12688990"
CDS 464853..465125
/gene="hupB"
/locus_tag="ECOK1_0422"
/note="identified by similarity to SP:P0ACF4; match to
protein family HMM PF00216"
/codon_start=1
/transl_table=11
/product="DNA-binding protein HU-beta"
/protein_id="YP_006099663.1"
/db_xref="GI:386598157"
/db_xref="GeneID:12688990"
/translation="MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVAL
VGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
misc_feature 464856..465116
/gene="hupB"
/locus_tag="ECOK1_0422"
/note="Integration host factor (IHF) and HU are small
heterodimeric members of the DNABII protein family that
bind and bend DNA, functioning as architectural factors in
many cellular processes including transcription,
site-specific recombination, and...; Region: HU_IHF;
cd00591"
/db_xref="CDD:238332"
misc_feature order(464856..464861,464868..464870,464877..464879,
464889..464891,464931..464933,464940..464945,
464952..464957,464967..464981,464988..464993,
465006..465008,465072..465077,465087..465089,
465093..465095,465114..465116)
/gene="hupB"
/locus_tag="ECOK1_0422"
/note="IHF dimer interface [polypeptide binding]; other
site"
/db_xref="CDD:238332"
misc_feature order(464856..464864,464928..464930,464973..464975,
464979..464981,464985..464990,464997..464999,
465009..465011,465015..465020,465024..465026,
465033..465044,465072..465074,465084..465086,
465090..465092,465099..465101)
/gene="hupB"
/locus_tag="ECOK1_0422"
/note="IHF - DNA interface [nucleotide binding]; other
site"
/db_xref="CDD:238332"
gene 465317..467188
/gene="ppiD"
/locus_tag="ECOK1_0423"
/db_xref="GeneID:12688991"
CDS 465317..467188
/gene="ppiD"
/locus_tag="ECOK1_0423"
/EC_number="5.2.1.8"
/note="identified by similarity to SP:P0ADY1; match to
protein family HMM PF00639"
/codon_start=1
/transl_table=11
/product="peptidyl-prolyl isomerase"
/protein_id="YP_006099664.1"
/db_xref="GI:386598158"
/db_xref="GeneID:12688991"
/translation="MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAK
VNDQEISRGQFENAFNSERNRMQQQLGDQYSELAANEGYMKTLRQQVLNRLIDEALLD
QYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQL
TTQQLINGVAGTDFMLKGETDELAALVAQQRVVREATIDVNALAAKQPVTEQEIASYY
EQNKNNFMTPEQFRVSYIKLDAATMQQPVSDADIQSYYDQHQDQFTQPQRTRYSIIQT
KTEDEAKAVLDELNKGGDFAALAKEKSADIISARNGGDMGWLEDATIPDELKNAGLKE
KGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDIAAKVKHEKALDAYYALQQKVS
DAASNDTESLAGAEQAAGVKATQTGWFSKDNLPEELNFKPVADAIFNGGLVGENGAPG
INSDIITVDGDRAFVLRISEHKPEAVKPLADVQEQVKALVQHNKAEQQAKVDAEKLLV
DLKAGKGAEAMQAAGLKFGEPKTLSRSGRDPISQAAFALPLPAKDKPSYGMATDMQGN
VVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
misc_feature 465317..467173
/gene="ppiD"
/locus_tag="ECOK1_0423"
/note="periplasmic folding chaperone; Provisional; Region:
PRK10788"
/db_xref="CDD:182731"
misc_feature 465395..465814
/gene="ppiD"
/locus_tag="ECOK1_0423"
/note="SurA N-terminal domain; Region: SurA_N_3; cl07813"
/db_xref="CDD:244798"
misc_feature 466055..466423
/gene="ppiD"
/locus_tag="ECOK1_0423"
/note="PPIC-type PPIASE domain; Region: Rotamase_2;
pfam13145"
/db_xref="CDD:221934"
gene 467339..467710
/locus_tag="ECOK1_0424"
/db_xref="GeneID:12688992"
CDS 467339..467710
/locus_tag="ECOK1_0424"
/note="identified by match to protein family HMM
TIGR00426"
/codon_start=1
/transl_table=11
/product="competence protein ComEA"
/protein_id="YP_006099665.1"
/db_xref="GI:386598159"
/db_xref="GeneID:12688992"
/translation="MKHGIKALLITLSLACAGMSHSALAAASVAKPTTVETKAEAPAA
QSKAAVPAKASDEEGTRVSINNASAEELARAMNGVGLKKAQAIVSYREEYGPFKTVED
LKQVPGMGNSLVERNLAVLTL"
misc_feature 467504..467707
/locus_tag="ECOK1_0424"
/note="competence protein ComEA helix-hairpin-helix repeat
region; Region: TIGR00426"
/db_xref="CDD:129520"
gene 467816..468214
/locus_tag="ECOK1_0425"
/db_xref="GeneID:12688993"
CDS 467816..468214
/locus_tag="ECOK1_0425"
/note="identified by match to protein family HMM PF03061;
match to protein family HMM TIGR00051"
/codon_start=1
/transl_table=11
/product="thioesterase family protein"
/protein_id="YP_006099666.1"
/db_xref="GI:386598160"
/db_xref="GeneID:12688 