LOCUS NC_001134 813184 bp DNA linear PLN 25-FEB-2013
DEFINITION Saccharomyces cerevisiae S288c chromosome II, complete sequence.
ACCESSION NC_001134
VERSION NC_001134.8 GI:330443482
DBLINK Project: 128
KEYWORDS TPA:inferential.
SOURCE Saccharomyces cerevisiae S288c
ORGANISM Saccharomyces cerevisiae S288c
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (bases 1 to 813184)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 2 (bases 1 to 813184)
AUTHORS Feldmann,H., Aigle,M., Aljinovic,G., Andre,B., Baclet,M.C.,
Barthe,C., Baur,A., Becam,A.M., Biteau,N., Boles,E. et al.
TITLE Complete DNA sequence of yeast chromosome II
JOURNAL EMBO J. 13 (24), 5795-5809 (1994)
PUBMED 7813418
REFERENCE 3 (bases 1 to 813184)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (14-FEB-2013) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 4 (bases 1 to 813184)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 5 (bases 1 to 813184)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 6 (bases 1 to 813184)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to BK006936.
On Apr 26, 2011 this sequence version replaced gi:50593115.
Sequence assembly version R64-1-1.
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-6215 Y08934.1 1-6215
5958-9963 Z35869.1 1-4006
5958-9963 Z35869.1 1-4006
8480-10849 Z35868.1 1-2370
10552-14243 Z35867.1 1-3692
13880-18319 Z35866.1 1-4440
17697-22587 Z35865.1 1-4885
21096-24097 Z35864.1 1-2998
23537-24948 Z35863.1 1-1413
24743-36991 Z35862.2 1-12242
28180-39144 Z35861.1 1-10962
38688-40902 Z35859.1 1-2215
40525-43176 Z35858.1 1-2654
43093-44258 Z35857.1 1-1166
44098-45977 Z35854.1 1-1880
44919-47365 Z35853.1 1-2447
46368-48824 Z35852.1 1-2457
48413-49423 Z35851.1 1-1011
49356-51021 Z35850.1 1-1666
50951-59824 Z35849.1 1-8873
59383-61204 Z35848.1 1-1822
60740-63875 Z35847.1 1-3137
62603-67171 Z35846.1 1-4569
66816-69715 Z35845.1 1-2900
69446-71865 Z35844.1 1-2420
71128-73072 Z35842.1 1-1945
72970-75258 Z35841.1 1-2289
74696-80380 Z35840.1 1-5685
79765-80896 Z35839.1 1-1133
80732-84501 Z35838.1 1-3771
84262-86724 Z35836.1 1-2463
86449-88525 Z35835.1 1-2077
87955-90225 Z35833.1 1-2271
89126-90607 Z35832.1 1-1482
90532-92329 Z35831.1 1-1798
91724-93817 Z35829.1 1-2098
93392-96810 Z35828.1 1-3419
95885-96810 Z35827.1 3-928
96640-97041 GU474014.1 1-402
96997-100373 Z35827.1 1078-4454
100305-101885 Z35825.1 1-1581
101157-105307 Z35824.1 1-4151
105219-107931 Z35823.1 1-2713
107407-110593 Z35821.1 1-3187
109993-111436 Z35820.1 1-1444
111245-112803 Z35819.1 1-1559
112706-113761 Z35818.1 1-1057
113445-115575 Z35817.1 1-2131
115166-117588 Z35816.1 1-2423
116830-119334 Z35815.1 1-2505
119164-122755 Z35814.1 1-3592
121875-125124 Z35812.1 1-3250
124760-126827 Z35811.1 1-2068
126117-127298 Z35810.1 1-1182
127242-127897 Z35809.1 1-656
127608-132423 Z35808.1 1-4816
132041-134145 Z35807.1 1-2105
133747-135997 Z35806.1 1-2251
135517-136687 Z35805.1 1-1171
136364-138343 Z35804.1 1-1980
137459-141246 Z35803.1 1-3788
140261-142114 Z35802.1 1-1854
141970-143991 Z35801.1 1-2022
142869-146186 Z35800.1 1-3318
145729-147208 Z35799.1 1-1480
146883-150449 Z35798.1 1-3567
150284-151495 Z35797.1 1-1212
151221-153850 Z35796.1 1-2630
153611-158658 Z35795.1 1-5048
158390-160183 Z35794.1 1-1794
159694-161698 Z35793.1 1-2005
161327-163043 Z35792.1 1-1717
162713-166133 Z35791.1 1-3421
163998-167520 Z35790.1 1-3523
166188-168422 Z35789.1 1-2235
167839-170622 Z35788.1 1-2784
169374-171480 Z35787.1 1-2107
171036-172533 Z35786.1 1-1498
171916-174922 Z35785.1 1-3007
174586-177876 Z35784.1 1-3291
177527-181662 Z35783.1 1-4136
181276-182400 Z35782.1 1-1125
182095-184352 Z35781.1 1-2258
184123-186000 Z35780.1 1-1878
185913-186846 Z35779.1 1-934
186475-192450 Z35778.1 1-5976
191584-194121 Z35777.1 1-2538
193510-199066 Z35776.1 1-5557
195700-202055 Z35775.1 1-6356
201749-203408 Z35774.1 1-1659
203236-206109 Z35773.1 1-2874
205815-207193 Z35771.1 1-1379
206950-209652 Z35770.1 1-2703
209222-212634 Z35769.1 1-3413
212173-216695 Z35768.1 1-4523
216367-217469 Z35767.1 1-1104
217130-227635 Z35766.1 1-10506
220398-235396 Z35765.1 1-14999
235115-236491 Z35764.1 1-1377
235793-237155 Z35763.1 1-1362
236885-238943 Z35762.1 1-2058
237468-241710 Z35870.1 1-4243
241284-242808 Z35871.1 1-1525
242569-244368 Z35872.1 1-1800
244228-245905 Z35873.1 1-1678
245295-247009 Z35874.1 1-1715
246545-248808 Z35875.1 1-2263
248315-252565 Z35876.1 1-4250
251017-255375 Z35877.1 1-4356
254210-256330 Z35878.1 1-2118
255685-257114 Z35879.1 1-1430
256739-259149 Z35880.1 1-2411
257976-265494 Z35881.1 1-7519
259567-266727 Z35882.1 1-7163
265882-267712 Z35883.1 1-1833
267337-270246 Z35884.1 1-2910
269504-270949 Z35885.1 1-1446
270631-274429 Z35886.1 1-3799
273704-276255 Z35887.1 1-2552
275528-279020 Z35888.1 1-3493
278353-281442 Z35889.1 1-3090
280605-283737 Z35890.1 1-3133
283342-284430 Z35891.1 1-1089
284269-289444 Z35892.1 1-5176
287926-290683 Z35893.1 1-2758
290348-292879 Z35894.1 1-2532
291866-294026 Z35895.1 1-2161
294020-294427 Z35896.1 1-408
294357-296371 Z35897.1 1-2015
296003-298291 Z35898.1 1-2289
297743-300165 Z35899.1 1-2423
299948-301518 Z35900.1 1-1571
301252-301943 Z35901.1 1-692
301819-304932 Z35902.1 1-3114
304701-306271 Z35903.1 1-1571
305977-309083 Z35904.1 1-3107
306956-310567 Z35905.1 1-3611
310314-311897 Z35906.1 1-1583
311453-315574 Z35907.1 1-4123
314787-316967 Z35908.1 1-2182
316508-318265 Z35909.1 1-1758
317862-320418 Z35910.1 1-2559
320133-321878 Z35911.1 1-1746
321610-324339 Z35912.1 1-2730
323946-328372 Z35913.1 1-4426
326060-330509 Z35914.1 1-4449
330093-331832 Z35915.1 1-1740
331512-332830 Z35916.1 1-1319
332358-334388 Z35917.1 1-2031
333090-337185 Z35918.1 1-4096
336819-338722 Z35919.1 1-1904
338336-339677 Z35921.1 1-1342
339353-343100 Z35922.1 1-3748
340752-344604 Z35923.1 1-3853
344133-347878 Z35924.1 1-3746
347302-352195 Z35925.1 1-4894
349382-353674 Z35926.1 1-4293
353294-356863 Z35927.1 1-3570
356084-360654 Z35928.1 1-4571
360188-364789 Z35929.1 1-4602
362515-365978 Z35930.1 1-3464
365720-366972 Z35931.1 1-1254
366324-368586 Z35932.1 1-2264
368189-370039 Z35934.1 1-1851
368757-372105 Z35935.1 1-3348
370700-373863 Z35936.1 1-3163
372736-376576 Z35937.1 1-3841
375691-379223 Z35938.1 1-3533
378434-380410 Z35939.1 1-1977
379935-382029 Z35940.1 1-2095
381044-383111 Z35941.1 1-2066
382672-386285 Z35942.1 1-3612
385986-387833 Z35943.1 1-1850
387524-390374 Z35944.1 1-2851
389214-391807 Z35945.1 1-2593
391392-393122 Z35946.1 1-1732
392294-395385 Z35947.1 1-3092
394130-398616 Z35948.1 1-4486
398278-401255 Z35949.1 1-2978
400891-406630 Z35950.1 1-5740
405252-409168 Z35951.1 1-3917
407170-411053 Z35952.1 1-3884
410627-415982 Z35953.1 1-5356
413979-420203 Z35954.1 1-6225
416904-423764 Z35955.1 1-6861
420247-424992 Z35956.1 1-4746
424827-426376 Z35957.1 1-1550
425780-427157 Z35959.1 1-1378
427059-427700 Z35960.1 1-642
427485-429550 Z35961.1 1-2066
429102-432035 Z35962.1 1-2934
430952-434408 Z35963.1 1-3457
434295-436020 Z35964.1 1-1726
435768-436950 Z35965.1 1-1183
436711-441514 Z35966.1 1-4804
441313-442929 Z35967.1 1-1618
442924-443823 Z35968.1 1-900
443588-445064 Z35970.1 1-1477
444694-447708 Z35971.1 1-3015
447324-449666 Z35972.1 1-2343
449314-450883 Z35973.1 1-1570
450654-452657 Z35974.1 1-2004
451970-453795 Z35975.1 1-1826
453222-454821 Z35976.1 1-1600
454531-457921 Z35977.1 1-3390
457367-458871 Z35978.1 1-1505
458363-461180 Z35979.1 1-2818
460219-462872 Z35980.1 1-2654
461874-467247 Z35981.1 1-5374
466046-469750 Z35983.1 1-3705
469618-474201 Z35984.1 1-4584
473927-477670 Z35985.1 1-3744
476438-479337 Z35987.1 1-2900
479045-480437 Z35988.1 1-1393
480321-481366 Z35989.1 1-1046
480924-483972 Z35990.1 1-3049
483368-484744 Z35991.1 1-1377
484561-487201 Z35992.1 1-2641
486864-488907 Z35994.1 1-2044
488381-491271 Z35995.1 1-2891
490393-493083 Z35996.1 1-2691
492823-494355 Z35997.1 1-1533
494116-495594 Z35998.1 1-1479
495340-497162 Z35999.1 1-1823
496870-499654 Z36000.1 1-2785
499275-501806 Z36001.1 1-2532
501443-504853 Z36002.1 1-3411
504508-505667 Z36004.1 1-1160
505304-513043 Z36005.1 1-7740
512772-513764 Z36006.1 1-993
513581-515663 Z36007.1 1-2083
515337-517352 Z36008.1 1-2016
517188-527027 Z36009.1 1-9840
526629-528316 Z36010.1 1-1688
528039-530871 Z36011.1 1-2833
530636-533237 Z36012.1 1-2602
532183-533761 Z36013.1 1-1579
533550-535259 Z36014.1 1-1710
534815-536574 Z36015.1 1-1760
536094-537875 Z36016.1 1-1782
537463-539986 Z36017.1 1-2524
539703-541211 Z36018.1 1-1509
541019-545027 Z36019.1 1-4009
543407-546375 Z36020.1 1-2969
545976-547459 Z36021.1 1-1484
547249-548364 Z36022.1 1-1116
548192-549770 Z36023.1 1-1579
549010-551106 Z36024.1 1-2097
550926-553991 Z36025.1 1-3066
553201-556548 Z36026.1 1-3347
554311-558684 Z36027.1 1-4374
558196-560077 Z36028.1 1-1882
559726-561633 Z36029.1 1-1909
560972-563205 Z36030.1 1-2235
562762-565722 Z36031.1 1-2961
564571-567877 Z36032.1 1-3307
567478-568851 Z36033.1 1-1374
568427-569844 Z36034.1 1-1418
569683-571470 Z36035.1 1-1788
571201-572370 Z36036.1 1-1170
571891-573917 Z36037.1 1-2027
573610-576346 Z36038.1 1-2737
575997-578363 Z36039.1 1-2367
578087-579152 Z36040.1 1-1066
578982-581728 Z36041.1 1-2747
581523-582340 Z36042.1 1-818
582173-583719 Z36043.1 1-1547
583353-584809 Z36045.1 1-1457
584656-586549 Z36046.1 1-1894
586443-589740 Z36048.1 1-3298
589115-591714 Z36049.1 1-2600
591457-593508 Z36050.1 1-2052
592775-596114 Z36051.1 1-3340
594865-597362 Z36052.1 1-2498
597063-599125 Z36053.1 1-2063
598932-600552 Z36054.1 1-1621
599960-602633 Z36055.1 1-2674
602161-603687 Z36056.1 1-1527
603202-604507 Z36057.1 1-1306
604108-605965 Z36058.1 1-1858
605506-607651 Z36059.1 1-2146
607138-609084 Z36061.1 1-1947
608783-610037 Z36062.1 1-1255
609754-610616 Z36063.1 1-863
610407-612238 Z36064.1 1-1832
611883-615205 Z36065.1 1-3323
613901-616129 Z36066.1 1-2229
615857-618908 Z36067.1 1-3052
618524-620871 Z36068.1 1-2348
619678-623785 Z36069.1 1-4109
622525-625771 Z36070.1 1-3247
624209-629167 Z36071.1 1-4958
628307-632256 Z36072.1 1-3950
631946-633621 Z36073.1 7-1682
633382-635145 Z36074.1 1-1764
634922-636705 Z36076.1 1-1784
636541-642582 Z36077.1 1-6042
642211-645549 Z36078.1 1-3339
642898-646160 Z36079.1 1-3263
645976-647885 Z36080.1 1-1910
647133-650367 Z36081.1 1-3235
649902-651414 Z36082.1 1-1513
651190-653445 Z36083.1 1-2256
652996-655578 Z36084.1 1-2583
655315-657831 Z36085.1 1-2517
657601-658709 Z36086.1 1-1109
658390-662501 Z36087.1 1-4112
662250-665155 Z36088.1 1-2906
664678-666722 Z36090.1 1-2045
666254-668665 Z36091.1 1-2412
668352-673574 Z36092.1 1-5223
673566-675312 Z36096.1 1-1747
675135-676359 Z36097.1 1-1225
676225-679551 Z36098.1 1-3327
679222-682181 Z36099.1 1-2960
680051-683375 Z36100.1 1-3325
683091-685440 Z36101.1 1-2350
684667-686900 Z36103.1 1-2234
686593-690385 Z36104.1 1-3793
690261-691968 Z36105.1 1-1708
691694-695109 Z36106.1 1-3416
694516-698356 Z36107.1 1-3841
697303-700492 Z36108.1 1-3190
699944-702591 Z36109.1 1-2648
699944-702591 Z36109.1 1-2648
701843-704669 Z36110.1 1-2827
701843-704669 Z36110.1 1-2827
704056-705449 Z36111.1 1-1394
705384-707527 Z36112.1 1-2144
706794-708152 Z36113.1 1-1359
708014-711590 Z36114.1 1-3577
711581-713006 Z36115.1 1-1426
712752-714809 Z36116.1 1-2058
714456-716884 Z36117.1 1-2429
716466-719032 Z36118.1 1-2567
717995-721389 Z36119.1 1-3395
720602-722610 Z36120.1 1-2009
722311-723269 Z36121.1 1-959
723052-723738 Z36122.1 1-687
723633-724455 Z36123.1 1-823
724264-727388 Z36124.1 1-3125
726538-728884 Z36125.1 1-2347
728103-729736 Z36126.1 1-1634
729722-730386 Z36127.1 1-665
730163-732641 Z36128.1 1-2479
732451-734834 Z36129.1 1-2384
734640-735722 Z36130.1 1-1083
735531-737772 Z36131.1 1-2242
737734-738581 Z36133.1 1-848
738427-739829 Z36134.1 1-1403
739542-741298 Z36135.1 1-1757
741020-742184 Z36137.1 1-1165
741614-742763 Z36138.1 1-1148
742577-744851 Z36139.1 1-2275
744399-746363 Z36140.1 1-1965
746109-748063 Z36141.1 1-1955
747804-749593 Z36142.1 1-1790
749372-751358 Z36143.1 1-1987
751175-757622 Z36144.1 1-6449
755044-760217 Z36145.1 1-5175
760044-761256 Z36146.1 1-1213
760897-762786 Z36148.1 1-1890
762592-764972 Z36149.1 1-2381
764713-768239 Z36150.1 1-3527
767607-768945 Z36151.1 1-1339
768678-771238 Z36152.1 1-2561
770416-773921 Z36153.1 1-3506
773630-774617 Z36154.1 1-988
774039-776570 Z36155.1 1-2532
776311-778014 Z36156.1 1-1704
777852-779666 Z36157.1 1-1815
779464-782590 Z36158.1 1-3127
782382-783675 Z36159.1 1-1294
783554-784704 Z36160.1 1-1151
784573-787005 Z36161.1 1-2432
785074-789234 Z36162.1 1-4160
788428-792848 Z36163.1 1-4420
791812-796800 Z36164.1 1-4988
796497-800522 Z36165.1 1-4026
798523-802633 Z36166.1 1-4111
801927-805350 Z36167.1 1-3424
804476-808602 Z36168.1 1-4127
807103-810342 Z36169.1 1-3240
809417-813184 Z36171.1 1-3768
FEATURES Location/Qualifiers
source 1..813184
/organism="Saccharomyces cerevisiae S288c"
/mol_type="genomic DNA"
/strain="S288c"
/db_xref="taxon:559292"
/chromosome="II"
telomere complement(1..6608)
/note="TEL02L; Telomeric region on the left arm of
Chromosome II; composed of an X element core sequence, X
element combinatorial repeats, and a short Y' element"
/db_xref="SGD:S000028867"
repeat_region complement(1..5848)
/note="TEL02L-YP; Telomeric short Y' element on the left
arm of Chromosome II; contains an ARS consensus sequence,
a region of 36-bp repeats, and four ORFs (YBL111C,
YBL112C, YBL113C, YBL113W-A)"
/rpt_family="Y' element"
/db_xref="SGD:S000028870"
gene complement(280..2658)
/locus_tag="YBL113C"
/db_xref="GeneID:852159"
mRNA complement(280..2658)
/locus_tag="YBL113C"
/product="hypothetical protein"
/transcript_id="NM_001180054.1"
/db_xref="GI:296142560"
/db_xref="GeneID:852159"
CDS complement(280..2658)
/locus_tag="YBL113C"
/note="Helicase-like protein encoded within the telomeric
Y' element"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009437.1"
/db_xref="GI:6319355"
/db_xref="SGD:S000002153"
/db_xref="GeneID:852159"
/translation="MDLNQRKEKKGQHVGCCGSRTDLSADTVELIERMDRLAENQATA
SMSIVALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSANASTNATTNSSTNATTTASI
NVRTSATTTASINVRTSATTTESTNSNTNATTTESTNSSTNATTTASINVRTSATTTE
STNSSTNATTTASINVRTSATTTESTNSSTNATTTASINVRTSATTTESTNSNTNAST
NATTNSSTNATTTASTNVRTSATTNATTNSSTNATTTASTNVRTSATTTASTNVRTSA
TTTASINVRTSATTTESINSSTNATTTESTNSNTSATTTESTDSNTNATTTASINVRT
SATTTESTNSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNATTTESTNA
SAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVFLERKKLKAQFPNTSENMNVLQ
FLGFRSDEIKHLFLYGIDIYFCPEGVFTQYGLCKGCQKMFGLCVCWAGQKVSYRRIAW
EALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKYFSVKRREIYSQIQRNYAWYLAIT
RRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEKKC
REEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSL
GMHLRDQLALGVTPSKVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEMWLLPHWLD
LANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDIILLCRDSSREVGE"
gene complement(2582..2899)
/locus_tag="YBL112C"
/db_xref="GeneID:852160"
mRNA complement(2582..2899)
/locus_tag="YBL112C"
/product="hypothetical protein"
/transcript_id="NM_001180053.1"
/db_xref="GI:296142561"
/db_xref="GeneID:852160"
CDS complement(2582..2899)
/locus_tag="YBL112C"
/note="hypothetical protein; YBL112C is contained within
TEL02L"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009438.1"
/db_xref="GI:6319356"
/db_xref="SGD:S000002152"
/db_xref="GeneID:852160"
/translation="MQVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDG
GLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGPACWMLWLQDR
PVC"
gene complement(2907..5009)
/locus_tag="YBL111C"
/db_xref="GeneID:852161"
mRNA complement(join(2907..4116,4216..5009))
/locus_tag="YBL111C"
/product="hypothetical protein"
/transcript_id="NM_001180052.1"
/db_xref="GI:296142562"
/db_xref="GeneID:852161"
CDS complement(join(2907..4116,4216..5009))
/locus_tag="YBL111C"
/note="Helicase-like protein encoded within the telomeric
Y' element; relocalizes from mitochondrion to cytoplasm
upon DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009439.1"
/db_xref="GI:6319357"
/db_xref="SGD:S000002151"
/db_xref="GeneID:852161"
/translation="MKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVR
SFYEDEKSGLIKVVKFRTGAMDRKRSFEKIVVSVMVGKNVQKFLTFVEDEPDFQGGPI
PSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCYEIA
SARPNDSSTMRTFTDFVSGTPIVRSLQKSTIRKYGYNLAPYMFLLLHVDELSIFSAYQ
ASLPGEKKVDTERLKRDLCPRKPTEIKYFSQICNDMMNKKDRLGDVLATAQRIRRRYN
KNGSSEPRLKTLDGLTSERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHDQKIS
RVTRKRPREPKSTNDILVAGRKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQAPPGY
GKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRRGCLNVAPVRNFIEEG
CDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVY
RQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSED
LSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAI
VVASTTNEVEELACSWRKYFRVVWIHGKLGCCRKGVSHKGVCH"
repeat_region complement(5849..6138)
/note="TEL02L-XR; Telomeric X element combinatorial Repeat
region on the left arm of Chromosome II; contains repeats
of the D, C, B and A types, Tbf1p binding sites, and ORF
YBL109W; formerly called SubTelomeric Repeats"
/rpt_family="X element Combinatorial Repeats"
/db_xref="SGD:S000028869"
repeat_region complement(6139..6608)
/note="TEL02L-XC; Telomeric X element Core sequence on the
left arm of Chromosome II, contains an ARS consensus
sequence and an Abf1p binding site consensus sequence"
/rpt_family="X element Core sequence"
/db_xref="SGD:S000028868"
gene complement(7605..7733)
/gene="PAU9"
/locus_tag="YBL108C-A"
/db_xref="GeneID:852163"
mRNA complement(7605..7733)
/gene="PAU9"
/locus_tag="YBL108C-A"
/product="Pau9p"
/transcript_id="NM_001184458.1"
/db_xref="GI:296142563"
/db_xref="GeneID:852163"
CDS complement(7605..7733)
/gene="PAU9"
/locus_tag="YBL108C-A"
/note="hypothetical protein, member of the seripauperin
multigene family encoded mainly in subtelomeric regions"
/codon_start=1
/product="Pau9p"
/protein_id="NP_076873.1"
/db_xref="GI:13129151"
/db_xref="SGD:S000007592"
/db_xref="GeneID:852163"
/translation="MLTGIAPDQVTRMITGVPWYSSRLKPAISSALSKDGIYTIAN"
LTR 8848..9092
/note="Ty1 LTR"
/db_xref="SGD:S000006798"
LTR 9093..9424
/note="Ty2 LTR"
/db_xref="SGD:S000006799"
LTR 9425..9518
/note="Ty1 LTR"
/db_xref="SGD:S000006800"
gene 9583..9666
/locus_tag="tL(UAA)B1"
/db_xref="GeneID:852166"
tRNA 9583..9666
/locus_tag="tL(UAA)B1"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006647"
/db_xref="GeneID:852166"
gene complement(9961..10551)
/gene="MIC23"
/locus_tag="YBL107C"
/db_xref="GeneID:852167"
mRNA complement(9961..10551)
/gene="MIC23"
/locus_tag="YBL107C"
/product="Mic23p"
/transcript_id="NM_001178347.1"
/db_xref="GI:296142564"
/db_xref="GeneID:852167"
CDS complement(9961..10551)
/gene="MIC23"
/locus_tag="YBL107C"
/note="Mitochondrial intermembrane space hypothetical
protein; imported via the MIA import machinery; contains
an unusual twin cysteine motif (CX13C CX14C)"
/codon_start=1
/product="Mic23p"
/protein_id="NP_009443.1"
/db_xref="GI:6319361"
/db_xref="SGD:S000000203"
/db_xref="GeneID:852167"
/translation="MVDNRRTFTAPQSLLETNLTFPNDEPSLTTITVTRERCVDPSLI
DSFLRFLRHGSDDIIRQKLNNYRKGSINGKNKCKEFLKQELYPNWQIRNNIISFCEKE
AAEMKNETDQQCGNNKKTTAEPLIDARIDPYAARERAEKQEAQYKDWTKVTEWVANNR
KIEQILTSTTEGILRQNCEQNNDYLKEFTQFCKDNS"
gene complement(10847..13879)
/gene="SRO77"
/locus_tag="YBL106C"
/gene_synonym="SNI2; SOP2"
/db_xref="GeneID:852168"
mRNA complement(10847..13879)
/gene="SRO77"
/locus_tag="YBL106C"
/gene_synonym="SNI2; SOP2"
/product="Sro77p"
/transcript_id="NM_001178346.2"
/db_xref="GI:330443392"
/db_xref="GeneID:852168"
CDS complement(10847..13879)
/gene="SRO77"
/locus_tag="YBL106C"
/gene_synonym="SNI2; SOP2"
/note="Protein with roles in exocytosis and cation
homeostasis; functions in docking and fusion of post-Golgi
vesicles with plasma membrane; homolog of Sro7p and
Drosophila lethal giant larvae tumor suppressor; interacts
with SNARE protein Sec9p"
/codon_start=1
/product="Sro77p"
/protein_id="NP_009444.2"
/db_xref="GI:330443393"
/db_xref="SGD:S000000202"
/db_xref="GeneID:852168"
/translation="MFKKSRHLKNVSNAIKSARVHDVSNGINSKFFDTKKICTYGING
RITVTTFDYTQSLLAVATTAGEIHVYGQKQIEVVFTLKNRPQIKHMRFIKGIYLIAVD
EKSNIIVLSVHSKQILTTVFCPNSITCIETDPSLDWMLIGLESGSILIYDVDRNQMSK
LKIENFQKSVFLPKERLSPVISIQWNPRDIGTILISYEHITVIYSFIDYKVKQHFFYQ
LEPYAPGGDLSTNIEKKRTPKVIQSLYHPNSLHILTVHEDNSLVFWDVNSGKLIHARS
IFETHVNFPNPALKDCSFTETPAIFKVSWLCQRNPEYTSLLIATKATENPCLPQEITM
IDLGGTPMYSVTSFDAMSKYYAKPVQQKLFSLIGKAPLINFLPLPKASPYFGGCHDTN
LILLLLEDGELETLIYPAGSFSSKASIFPRSLAWVRPTVTTCIAQSVQKNLWLGMMTI
AQSESFLKGGIPATRNIRRHETRSALLTGHSNGSVRIWDASHSEVTDNAVFEVNTAKV
LNRATNLAIKNISFASETLELAVSSEVGDVILFKFETNKFYGQLPKSDALQLKFSRFS
LDDSKTILVDVSDRGPTNVKQGFIPSTVIHAKKGAVSAIMNSNIGFVAVGFIEGTLII
LDRRGPAIIFNENIRVISKAGSSYVSTVHFCVMEYGDDGFSSILMLCGTDIGELMTFK
ILPATNGRFEVKFTDATKTNNQGKILGINSFAKDTGYSCSATISKMQGLSKGIAIPGF
VTISGANDIRLVSPGKSKDTHALFKYPIATSGLSFIPIIDGKGERKLSTIMIVLLING
DIKVLTVPELKEVKNLRCPVPLSAQYVENSSILENGDIVIRTGKFQASLISVLNESAT
GTNHTADISQHTPIDTLYNPDLKIGYRPQVNSLQWARGTIYCTPYQLDELLGGIERPE
SKYEESAIARGCISSSSSNAARKLPPGTEDHRYARPVRSSGRSNGYGVLKSVSRAIET
RLDTVETTINDYATTMGQTMNDAMEETGRDMMKSAVGF"
gene complement(14241..17696)
/gene="PKC1"
/locus_tag="YBL105C"
/gene_synonym="CLY15; HPO2; STT1"
/db_xref="GeneID:852169"
mRNA complement(14241..17696)
/gene="PKC1"
/locus_tag="YBL105C"
/gene_synonym="CLY15; HPO2; STT1"
/product="Pkc1p"
/transcript_id="NM_001178345.2"
/db_xref="GI:330443394"
/db_xref="GeneID:852169"
CDS complement(14241..17696)
/gene="PKC1"
/locus_tag="YBL105C"
/gene_synonym="CLY15; HPO2; STT1"
/EC_number="2.7.11.13"
/note="Protein serine/threonine kinase essential for cell
wall remodeling during growth; localized to sites of
polarized growth and the mother-daughter bud neck; homolog
of the alpha, beta, and gamma isoforms of mammalian
protein kinase C (PKC)"
/codon_start=1
/product="Pkc1p"
/protein_id="NP_009445.2"
/db_xref="GI:330443395"
/db_xref="SGD:S000000201"
/db_xref="GeneID:852169"
/translation="MSFSQLEQNIKKKIAVEENIIRGASALKKKTSNVMVIQKCNTNI
REARQNLEYLEDSLKKLRLKTAQQSQGENGSEDNERCNSKEYGFLSTKSPNEHIFSRL
DLVKYDCPSLAQRIQYMLQQLEFKLQVEKQYQEANTKLTKLYQIDGDQRSSSAAEGGA
MESKYRIQMLNKALKKYQAINVDFDQFKHQPNDIMDNQQPKFRRKQLTGVLTIGITAA
RDVDHIQSPMFARKPESYVTIKIDDTIKARTKPSRNDRWSEDFQIPVEKGNEIEITVY
DKVNDSLIPVAIMWLLLSDIAEEIRKKKAGQTNEQQGWVNASNINGGSSLASEEGSTL
TSTYSNSAIQSTSAKNVQGENTSTSQISTNSWFVLEPSGQILLTLGFHKSSQIERKQL
MGGLHRHGAIINRKEEIFEQHGHHFVQKSFYNIMCCAYCGDFLRYTGFQCQDCKFLCH
KKCYTNVVTKCIAKTSTDTDPDEAKLNHRIPHRFLPTSNRGTKWCCHCGYILPWGRHK
VRKCSECGIMCHAQCAHLVPDFCGMSMEMANKILKTIQDTKRNQEKKKRTVPSAQLGS
SIGTANGSDLSPSKLAERANAPLPPQPRKHDKTPSPQKVGRDSPTKQHDPIIDKRISL
QTHGREKLNKFIDENEAYLNFTEGAQQTAEFSSPEKTLDPTSNRRSLGLTDLSIEHSQ
TWESKDDLMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHIDLETKQKLDWENKND
FREADLTIDSTHTNPFRDMNSETFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSP
QKSQTSTSAKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLK
KDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMW
HVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCK
DEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDED
EVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINF
DDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTLTPLPSVLTTSQQEEFRGFSFMP
DDLDL"
gene complement(18177..21293)
/gene="SEA4"
/locus_tag="YBL104C"
/gene_synonym="YBL103C-A"
/db_xref="GeneID:852170"
mRNA complement(18177..21293)
/gene="SEA4"
/locus_tag="YBL104C"
/gene_synonym="YBL103C-A"
/product="Sea4p"
/transcript_id="NM_001178344.1"
/db_xref="GI:296142567"
/db_xref="GeneID:852170"
CDS complement(18177..21293)
/gene="SEA4"
/locus_tag="YBL104C"
/gene_synonym="YBL103C-A"
/note="Subunit of the SEA (Seh1-associated) complex, a
coatomer-related complex that associates dynamically with
the vacuole; has an N-terminal beta-propeller fold and a
C-terminal RING motif; promoter contains multiple GCN4
binding sites"
/codon_start=1
/product="Sea4p"
/protein_id="NP_009446.2"
/db_xref="GI:41629671"
/db_xref="SGD:S000000200"
/db_xref="GeneID:852170"
/translation="MGLIKKVTHWSYDNLIDYLSVNPTRDEVTHYKVDPENESDESII
KLHTVKDFGSITCLDYSESEIGMIGVGEKNGYLRIFNISGQNSSSPASHAPVGLNANN
ETSMTNASGGKAAQAENIVGSVSNLKDTQGYPVSETNYDIRVRAKKQRCINSLGINTN
GLIAMGLDRNKHDSSLQIWDMNYHDDSHETINPMFSYCTNESIVSLKFLNDTSVLAAS
TKFLKEIDVRSPNPIYQHPTRLTYDIKLNPFNDWQFSTYGDDGTLAIWDRRKLSDQAS
LGDLNVASPLLTFEKLVGSGAASRKYMNSCFRWSCVRNNEFATLHRGDTIKRWRLGYY
CDSNRDIAADDDNEMNIENLFVSSVHDTNTMYDRVATFDYIPRSNNGTSLICMRQSGT
IYRMPISEVCSKAILNNRNSLLLSNFENTEIDEIRVNNEHEKSNLENVKTILKNLSFE
DLDVSEDYFPSGHDEPNNEIEYSELSEEENEGSNDVLDSKRGFELFWKPEKLLEKDIS
VIMRTRASLGYGLDPMNTVEMIDSSKNLQNNAYIRNTWRWIAIAKASVDDGTMVSGDL
DLGYEGVIGIWNGINGISNQDRYRQETILSDKQLNKEMEKIIKLRRKNRDRNSPIANA
AGSPKYVQRRLCLIISGWDLSRSDYEDKYNIIMKNGHYEKAAAWAVFFGDIPKAVEIL
GSAKKERLRLIATAIAGYLAYKDLPGNNAWRQQCRKMSSELDDPYLRVIFAFIADNDW
WDILYEPAISLRERLGVALRFLNDTDLTTFLDRTSSTVIENGELEGLILTGITPNGID
LLQSYVNKTSDVQSAALISIFGSPRYFRDQRVDEWIQTYRDMLKSWELFSMRARFDVL
RSKLSRTKTGVLTADIKPRQIYIQCQNCKQNINTPRTSSPSSAVSTSAGNYKNGEAYR
RNNADYKKFNTGSSEAQAADEKPRHKYCCPHCGSSFPRCAICLMPLGTSNLPFVINGT
QSRDPMQTEDSQDGANRELVSRKLKLNEWFSFCLSCNHGMHAGHAEEWFDRHNVCPTP
GCTCQCNK"
gene complement(22076..23536)
/gene="RTG3"
/locus_tag="YBL103C"
/db_xref="GeneID:852171"
mRNA complement(22076..23536)
/gene="RTG3"
/locus_tag="YBL103C"
/product="Rtg3p"
/transcript_id="NM_001178343.1"
/db_xref="GI:296142568"
/db_xref="GeneID:852171"
CDS complement(22076..23536)
/gene="RTG3"
/locus_tag="YBL103C"
/note="Basic helix-loop-helix-leucine zipper (bHLH/Zip)
transcription factor that forms a complex with another
bHLH/Zip protein, Rtg1p, to activate the retrograde (RTG)
and TOR pathways"
/codon_start=1
/product="Rtg3p"
/protein_id="NP_009447.1"
/db_xref="GI:6319365"
/db_xref="SGD:S000000199"
/db_xref="GeneID:852171"
/translation="MMNNNESEAENQRLLDELMNQTKVLQETLDFSLVTPTPHHNDDY
KIHGSAYPGGETPAQQHEKLSYINTHNSNDNNNLMGSQARSNSQTPTASTIYEEAESQ
SSYLDDMFRTSQGGRPVTQNSISSIGQGPLRSSYSMAYDSPVDRAMNTPLQQQEGLKA
ELPHDFLFQHGTDDTMYNLTDDLSSSLSSSINSDMMTPNTYSSSFSYNPQSLGPASVS
STYSPKVRSPSSSFRAGSFLSSSFRHGSINTPRTRHTSISSNMTENIGPGSVPKILGG
LTSDEKLRRKREFHNAVERRRRELIKQKIKELGQLVPPSLLNYDDLGKQIKPNKGIIL
DRTVEYLQYLAEILEIQARKKKALLAKIKELEEKKSSVAALSPFTNNHHASSGQNNSE
NSEERIIDIRSVPNALMNEQNSKAELHNWEPPLYDSVGNHNHAGTMESHPHTNIHEEL
KEFLSGDLIEAEDNAKLMFGDDNSNPADYLLEFGSG"
gene 24098..24745
/gene="SFT2"
/locus_tag="YBL102W"
/db_xref="GeneID:852172"
mRNA 24098..24745
/gene="SFT2"
/locus_tag="YBL102W"
/product="Sft2p"
/transcript_id="NM_001178342.1"
/db_xref="GI:296142569"
/db_xref="GeneID:852172"
CDS 24098..24745
/gene="SFT2"
/locus_tag="YBL102W"
/note="Non-essential tetra-spanning membrane protein found
mostly in the late Golgi, can suppress some sed5 alleles;
may be part of the transport machinery, but precise
function is unknown; similar to mammalian syntaxin 5"
/codon_start=1
/product="Sft2p"
/protein_id="NP_009448.1"
/db_xref="GI:6319366"
/db_xref="SGD:S000000198"
/db_xref="GeneID:852172"
/translation="MSEEPPSDQVNSLRDSLNRWNQTRQQNSQGFNESAKTLFSSWAD
SLNTRAQDIYQTLPVSRQDLVQDQEPSWFQLSRTERMVLFVCFLLGATACFTLCTFLF
PVLAAKPRKFGLLWTMGSLLFVLAFGVLMGPLAYLKHLTARERLPFSMFFFATCFMTI
YFAAFSKNTVLTITCALLELVAVIYYAISYFPFGATGLRMLSSAGVNSARGVLRI"
gene complement(24946..28299)
/gene="ECM21"
/locus_tag="YBL101C"
/gene_synonym="ART2"
/db_xref="GeneID:852173"
mRNA complement(24946..28299)
/gene="ECM21"
/locus_tag="YBL101C"
/gene_synonym="ART2"
/product="Ecm21p"
/transcript_id="NM_001178341.1"
/db_xref="GI:296142570"
/db_xref="GeneID:852173"
CDS complement(24946..28299)
/gene="ECM21"
/locus_tag="YBL101C"
/gene_synonym="ART2"
/note="Protein involved in regulating the endocytosis of
plasma membrane proteins; identified as a substrate for
ubiquitination by Rsp5p and deubiquitination by Ubp2p;
promoter contains several Gcn4p binding elements"
/codon_start=1
/product="Ecm21p"
/protein_id="NP_009449.1"
/db_xref="GI:6319367"
/db_xref="SGD:S000000197"
/db_xref="GeneID:852173"
/translation="MPFITSRPVAKNSSHSLSETDLNQSKGQPFQPSPTKKLGSMQQR
RRSSTIRHALSSLLGGANVHSPAVLNNTTKGGNNNGNIRSSNTDAQLLGKKQNKQPPP
NARRHSTTAIQGSISDSATTTPRSSTSDTNRRTSGRLSVDQEPRISGGRYSQIEEDST
VLDFDDDHNSSAVVSSDLSSTSLTRLANSKKFNEQFLIEYLTARGLLGPKTVLSNEYL
KISISTSGESVFLPTISSNDDEYLSRLNGLNDGTDDAEADFFMDGIDQQEGNTPSLAT
TAAATESGGSINENRDTLLRENNSGDHPGSGSELNTRSVEIDSSMVSYSIAVIVSVKK
PTRFTDMQLELCSRVKVFWNTGVPPTKTFNEEFYNAASMKWNLNDENFDLFVPLSISP
DDQMIENNSNDRQMRLFKNIPTEERLYLDKTKTKASLLNAIDVNKTHLYQPGDYVFLV
PVVFSNHIPETIYLPSARVSYRLRLATKAINRKGFYRQDSNSPQPIVSPDSSSSLSST
TSSLKLTETESAQAHRRISNTLFSKVKNHLHMSSHQLKNEESGEEDIFAEYPIKVIRT
PPPVAVSTANKPIYINRVWTDSLSYEISFAQKYVSLNSEVPIKIKLAPICKNVCVKRI
HVSITERVTFVSKGYEYEYDQTDPVAKDPYNPYYLDFASKRRKERSVSLFEIRTKEKG
TRALREEIVENSFNDNLLSYSPFDDDSDSKGNPKERLGITEPIIIETKLKFPKYEDLD
KRTAKIIPPYGIDAYTSIPNPEHAVANGPSHRRPSVIGFLSGHKGSKSHEENEKPVYD
PKFHQTIIKSNSGLPVKTHTRLNTPKRGLYLDSLHFSNVYCRHKLEIMLRISKPDPEC
PSKLRHYEVLIDTPIFLVSEQCNSGNMELPTYDMATMEGKGNQVPLSMNSDFFGNTCP
PPPTFEEAISVPASPIVSPMGSPNIMASYDPDLLSIQQLNLSRTTSVSGPSGYSDDAG
VPNVNRNSISNANAMNGSISNSAFVSGNSGQGVARARATSVNDRSRFNNLDKLLSTPS
PVNRSHNSSPTNGLSQANGTVRIPNATTENSKDKQNEFFKKGYTLANVKDDEEQEGIV
SSSSADSLLSHGNEPPRYDEIVPLMSDEE"
gene 28427..28546
/locus_tag="YBL100W-C"
/gene_synonym="YBL101W-C"
/db_xref="GeneID:1466439"
mRNA 28427..28546
/locus_tag="YBL100W-C"
/gene_synonym="YBL101W-C"
/product="hypothetical protein"
/transcript_id="NM_001184585.1"
/db_xref="GI:296142571"
/db_xref="GeneID:1466439"
CDS 28427..28546
/locus_tag="YBL100W-C"
/gene_synonym="YBL101W-C"
/note="hypothetical protein; identified by gene-trapping,
microarray-based expression analysis, and genome-wide
homology searching"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878043.1"
/db_xref="GI:33438761"
/db_xref="SGD:S000028598"
/db_xref="GeneID:1466439"
/translation="MSRSIFFFSSLFLSPLNKIRNIGGKVENPWKSQIRDWKN"
rep_origin 28942..29160
/note="ARS230;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118996"
mobile_element 29644..35602
/note="YBLWTy2-1; Ty2 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YBLWTy2-1"
/db_xref="SGD:S000006809"
LTR 29644..29975
/note="Ty2 LTR"
/db_xref="SGD:S000006801"
gene 29935..35248
/locus_tag="YBL100W-B"
/db_xref="GeneID:852175"
mRNA join(<29935..31227,31229..>35248)
/locus_tag="YBL100W-B"
/transcript_id="NM_001180050.1"
/db_xref="GI:296142573"
/db_xref="GeneID:852175"
CDS join(29935..31227,31229..35248)
/locus_tag="YBL100W-B"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_009450.1"
/db_xref="GI:6319369"
/db_xref="SGD:S000002149"
/db_xref="GeneID:852175"
/translation="MESQQLHQNPHSLHGSAYASVTSKEVSSNQDPLAVSASNLPEFD
RDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWA
HYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQDQHSEVPQAKTK
VRNNVLPPHTLTSEENFYTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYN
TFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGS
TSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQ
LFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPR
AAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLGQQQKESKPTHTIDSNDEL
PDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKT
SIKALHTPNIAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKY
LIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIE
WSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSY
FISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNK
TLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEF
STIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYA
LHPSRNSYGYIIYLPSLKKTVDTTNYVILQDNQSKLDQFNYDTLTFDDDLNRLTAHNQ
SFIEQNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSMNPLQLDHEPVQKVRAL
KEVDADISEYNILPSPVRSRTPHIINKESTEMGGTIESDTTSPRHSSTFTARNQKRPG
SPNDMIDLTSQDRVNYELENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSP
DSDSTTPIISIETKAACDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDL
PLPDLTNKSPTDTSDVSKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEI
EVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNEDNKEK
DRYIEAYHKEINQLLRMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVAR
GDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIR
PPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVT
ICLFVDDMILFSKDLNANEKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRSK
YMKLGMEKSLTEKLPKLNVPLNPKGKKLSAPGQPGHYIDQDELEIDEDEYKEKVHEMQ
KLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHK
NKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEI
HAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAM
RLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene 29935..31251
/locus_tag="YBL100W-A"
/db_xref="GeneID:852174"
mRNA <29935..>31251
/locus_tag="YBL100W-A"
/transcript_id="NM_001180049.1"
/db_xref="GI:296142572"
/db_xref="GeneID:852174"
CDS 29935..31251
/locus_tag="YBL100W-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_009451.1"
/db_xref="GI:6319368"
/db_xref="SGD:S000002148"
/db_xref="GeneID:852174"
/translation="MESQQLHQNPHSLHGSAYASVTSKEVSSNQDPLAVSASNLPEFD
RDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWA
HYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQDQHSEVPQAKTK
VRNNVLPPHTLTSEENFYTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYN
TFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGS
TSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQ
LFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPR
AAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLRPATERI"
LTR 35271..35602
/note="Ty2 LTR"
/db_xref="SGD:S000006802"
LTR 35604..35796
/note="Ty1 LTR"
/db_xref="SGD:S000006803"
LTR complement(35851..36221)
/note="Ty4 LTR"
/db_xref="SGD:S000006807"
gene 36398..36488
/locus_tag="tF(GAA)B"
/db_xref="GeneID:852176"
tRNA join(36398..36434,36453..36488)
/locus_tag="tF(GAA)B"
/product="tRNA-Phe"
/note="Phenylalanine tRNA (tRNA-Phe), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006562"
/db_xref="GeneID:852176"
gene 37053..38690
/gene="ATP1"
/locus_tag="YBL099W"
/db_xref="GeneID:852177"
mRNA 37053..38690
/gene="ATP1"
/locus_tag="YBL099W"
/product="F1F0 ATP synthase subunit alpha"
/transcript_id="NM_001178339.2"
/db_xref="GI:330443396"
/db_xref="GeneID:852177"
CDS 37053..38690
/gene="ATP1"
/locus_tag="YBL099W"
/EC_number="3.6.3.14"
/note="Alpha subunit of the F1 sector of mitochondrial
F1F0 ATP synthase, which is a large, evolutionarily
conserved enzyme complex required for ATP synthesis;
phosphorylated"
/codon_start=1
/product="F1F0 ATP synthase subunit alpha"
/protein_id="NP_009453.2"
/db_xref="GI:330443397"
/db_xref="SGD:S000000195"
/db_xref="GeneID:852177"
/translation="MLARTAAIRSLSRTLINSTKAARPAAAALASTRRLASTKAQPTE
VSSILEERIKGVSDEANLNETGRVLAVGDGIARVFGLNNIQAEELVEFSSGVKGMALN
LEPGQVGIVLFGSDRLVKEGELVKRTGNIVDVPVGPGLLGRVVDALGNPIDGKGPIDA
AGRSRAQVKAPGILPRRSVHEPVQTGLKAVDALVPIGRGQRELIIGDRQTGKTAVALD
TILNQKRWNNGSDESKKLYCVYVAVGQKRSTVAQLVQTLEQHDAMKYSIIVAATASEA
APLQYLAPFTAASIGEWFRDNGKHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGD
VFYLHSRLLERAAKLSEKEGSGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAE
LFYKGIRPAINVGLSVSRVGSAAQVKALKQVAGSLKLFLAQYREVAAFAQFGSDLDAS
TKQTLVRGERLTQLLKQNQYSPLATEEQVPLIYAGVNGHLDGIELSRIGEFESSFLSY
LKSNHNELLTEIREKGELSKELLASLKSATESFVATF"
gene 39145..40527
/gene="BNA4"
/locus_tag="YBL098W"
/db_xref="GeneID:852179"
mRNA 39145..40527
/gene="BNA4"
/locus_tag="YBL098W"
/product="kynurenine 3-monooxygenase"
/transcript_id="NM_001178338.1"
/db_xref="GI:296142575"
/db_xref="GeneID:852179"
CDS 39145..40527
/gene="BNA4"
/locus_tag="YBL098W"
/EC_number="1.14.13.9"
/note="Kynurenine 3-mono oxygenase, required for the de
novo biosynthesis of NAD from tryptophan via kynurenine;
expression regulated by Hst1p; putative therapeutic target
for Huntington disease"
/codon_start=1
/product="kynurenine 3-monooxygenase"
/protein_id="NP_009454.1"
/db_xref="GI:6319372"
/db_xref="SGD:S000000194"
/db_xref="GeneID:852179"
/translation="MSESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKN
KNLKSINLAISARGIDALKSIDPDACEHILQDMIPMKGRMIHDLKGRQESQLYGLHGE
AINSINRSVLNNSLLDELEKSTTELKFGHKLVKIEWTDDKQICHFAIGEDLKTPHTEK
YDFVIGCDGAYSATRSQMQRKVEMDFSQEYMNLRYIELYIPPTEEFKPNYGGNFAIAP
DHLHIWPRHKFMLIALANSDGSFTSTFFGSKDQISDLITSKSRVREFLIENFPDIINI
MDLDDAVKRFITYPKESLVCVNCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDV
RILMALLKKHSGDRSRAFTEYTQTRHKDLVSITELAKRNYKEMSHDVTSKRFLLRKKL
DALFSIIMKDKWIPLYTMISFRSDISYSRALERAGKQTRILKFLESLTLGMLSIGGYK
LFKFLTRERS"
gene 40831..43095
/gene="BRN1"
/locus_tag="YBL097W"
/db_xref="GeneID:852180"
mRNA 40831..43095
/gene="BRN1"
/locus_tag="YBL097W"
/product="Brn1p"
/transcript_id="NM_001178337.2"
/db_xref="GI:330443398"
/db_xref="GeneID:852180"
CDS 40831..43095
/gene="BRN1"
/locus_tag="YBL097W"
/note="Subunit of the condensin complex; required for
chromosome condensation and for clustering of tRNA genes
at the nucleolus; may influence multiple aspects of
chromosome transmission"
/codon_start=1
/product="Brn1p"
/protein_id="NP_009455.3"
/db_xref="GI:330443399"
/db_xref="SGD:S000000193"
/db_xref="GeneID:852180"
/translation="MTTQLRYENNDDDERVEYNLFTNRSTMMANFEEWIKMATDNKIN
SRNSWNFALIDYFYDLDVLKDGENNINFQKASATLDGCIKIYSSRVDSVTTETGKLLS
GLAQRKTNGASNGDDSNGGNGEGLGGDSDEANIEIDPLTGMPISNDPDVNNTRRRVYN
RVLETTLVEFETIKMKELDQELIIDPLFKKALVDFDEGGAKSLLLNTLNIDNTARVIF
DASIKDTQNVGQGKLQRKEEELIERDSLVDDENEPSQSLISTRNDSTVNDSVISAPSM
EDEILSLGMDFIKFDQIAVCEISGSIEQLRNVVEDINQAKDFIENVNNRFDNFLTEEE
LQAAVPDNAEDDSDGFDMGMQQELCYPDENHDNTSHDEQDDDNVNSTTGSIFEKDLMA
YFDENLNRNWRGREHWKVRNFKKANLVNKESDLLEETRTTIGDTTDKNTTDDKSMDTK
KKHKQKKVLEIDFFKTDDSFEDKVFASKGRTKIDMPIKNRKNDTHYLLPDDFHFSTDR
ITRLFIKPGQKMSLFSHRKHTRGDVSSGLFEKSTVSANHSNNDIPTIADEHFWADNYE
RKEQEEKEKEQSKEVGDVVGGALDNPFEDDMDGVDFNQAFEGTDDNEEASVKLDLQDD
EDHKFPIRENKVTYSRVSKKVDVRRLKKNVWRSINNLIQEHDSRKNREQSSNDSETHT
EDESTKELKFSDIIQGISKMYSDDTLKDISTSFCFICLLHLANEHGLQITHTENYNDL
IVNYEDLATTQAAS"
gene 43277..44089
/locus_tag="YBL095W"
/db_xref="GeneID:852181"
mRNA 43277..44089
/locus_tag="YBL095W"
/product="hypothetical protein"
/transcript_id="NM_001178335.1"
/db_xref="GI:296142577"
/db_xref="GeneID:852181"
CDS 43277..44089
/locus_tag="YBL095W"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009457.1"
/db_xref="GI:6319374"
/db_xref="SGD:S000000191"
/db_xref="GeneID:852181"
/translation="MSRTIPFLFKLVNRAVILPTAGFTLGVGAFVKAWPDDAGVLSLN
DPQTPAELISATKSRQPMELQRVDILAQIEKSEVYNKLAQDEKMHHVLFSEKIPSGHR
EYHVGQGLLFGKGKLEIDPLVFHDVNHGELTVIYHLGAELGNRDGNVHKGLLSLLLDE
ALCYCGFPLLPSKRGVTARLSLEFFEDIPVDTTIILKANVKEIKGRKCIIEGHLEQFP
LEVSSRNGTRSWNLPHIWGFNHKQEMAKKFAKANCILVEPTWFKYFKWLDMF"
gene complement(44256..44918)
/gene="ROX3"
/locus_tag="YBL093C"
/gene_synonym="MED19; NUT3; SSN7"
/db_xref="GeneID:852184"
mRNA complement(44256..44918)
/gene="ROX3"
/locus_tag="YBL093C"
/gene_synonym="MED19; NUT3; SSN7"
/product="Rox3p"
/transcript_id="NM_001178333.1"
/db_xref="GI:296142578"
/db_xref="GeneID:852184"
CDS complement(44256..44918)
/gene="ROX3"
/locus_tag="YBL093C"
/gene_synonym="MED19; NUT3; SSN7"
/note="Subunit of the RNA polymerase II mediator complex;
associates with core polymerase subunits to form the RNA
polymerase II holoenzyme"
/codon_start=1
/product="Rox3p"
/protein_id="NP_009459.1"
/db_xref="GI:6319377"
/db_xref="SGD:S000000189"
/db_xref="GeneID:852184"
/translation="MASRVDETTVPSYYYYVDPETTYTYQQPNPLQDLISVYGLDDIS
RQVARTNLDGTKAVKLRKSYKNQIADLSGKFSTIPTRENGKGGQIAHILFQNNPDMMI
QPPQQGQNMSEQQWREQLRNRDIALFQPPNFDWDLCSSVLSQFERSYPSEFANQNQGG
AQAPFDIDDLAFDLDGTGKSQSGSNSGNNSKKRKNKSSGSSMATPTHSDSHEDMKRRR
LE"
gene 45978..46370
/gene="RPL32"
/locus_tag="YBL092W"
/db_xref="GeneID:852185"
mRNA 45978..46370
/gene="RPL32"
/locus_tag="YBL092W"
/product="ribosomal 60S subunit protein L32"
/transcript_id="NM_001178332.1"
/db_xref="GI:296142579"
/db_xref="GeneID:852185"
CDS 45978..46370
/gene="RPL32"
/locus_tag="YBL092W"
/note="Ribosomal 60S subunit protein L32; overexpression
disrupts telomeric silencing; homologous to mammalian
ribosomal protein L32, no bacterial homolog"
/codon_start=1
/product="ribosomal 60S subunit protein L32"
/protein_id="NP_009460.1"
/db_xref="GI:6319378"
/db_xref="SGD:S000000188"
/db_xref="GeneID:852185"
/translation="MASLPHPKIVKKHTKKFKRHHSDRYHRVAENWRKQKGIDSVVRR
RFRGNISQPKIGYGSNKKTKFLSPSGHKTFLVANVKDLETLTMHTKTYAAEIAHNISA
KNRVVILARAKALGIKVTNPKGRLALEA"
gene complement(46565..47180)
/gene="SCS22"
/locus_tag="YBL091C-A"
/db_xref="GeneID:852186"
mRNA complement(join(46565..47058,47147..47180))
/gene="SCS22"
/locus_tag="YBL091C-A"
/product="Scs22p"
/transcript_id="NM_001184321.1"
/db_xref="GI:296142580"
/db_xref="GeneID:852186"
CDS complement(join(46565..47058,47147..47180))
/gene="SCS22"
/locus_tag="YBL091C-A"
/note="Protein involved in regulation of phospholipid
metabolism; homolog of Scs2p; similar to D. melanogaster
inturned protein"
/codon_start=1
/product="Scs22p"
/protein_id="NP_009461.2"
/db_xref="GI:41629673"
/db_xref="SGD:S000007228"
/db_xref="GeneID:852186"
/translation="MRIVPEKLVFKAPLNKQSTEYIKLENDGEKRVIFKVRTSAPTKY
CVRPNVAIIGAHESVNVQIVFLGLPKSTADDEMDQKRDKFLIVTLPIPAAYQNVEDGE
LLSDWPNLEEQYKDDIVFKKIKIFHSVLPKRKPSGNHDAESARAPSAGNGQSLSSRAL
LIITVIALLVGWIYY"
gene complement(47363..48628)
/gene="MAP2"
/locus_tag="YBL091C"
/db_xref="GeneID:852187"
mRNA complement(47363..48628)
/gene="MAP2"
/locus_tag="YBL091C"
/product="Map2p"
/transcript_id="NM_001178331.2"
/db_xref="GI:330443400"
/db_xref="GeneID:852187"
CDS complement(47363..48628)
/gene="MAP2"
/locus_tag="YBL091C"
/EC_number="3.4.11.18"
/note="Methionine aminopeptidase, catalyzes the
cotranslational removal of N-terminal methionine from
nascent polypeptides; function is partially redundant with
that of Map1p"
/codon_start=1
/product="Map2p"
/protein_id="NP_009462.2"
/db_xref="GI:330443401"
/db_xref="SGD:S000000187"
/db_xref="GeneID:852187"
/translation="MTDAEIENSPASDLKELNLENEGVEQQDQAKADESDPVESKKKK
NKKKKKKKSNVKKIELLFPDGKYPEGAWMDYHQDFNLQRTTDEESRYLKRDLERAEHW
NDVRKGAEIHRRVRRAIKDRIVPGMKLMDIADMIENTTRKYTGAENLLAMEDPKSQGI
GFPTGLSLNHCAAHFTPNAGDKTVLKYEDVMKVDYGVQVNGNIIDSAFTVSFDPQYDN
LLAAVKDATYTGIKEAGIDVRLTDIGEAIQEVMESYEVEINGETYQVKPCRNLCGHSI
APYRIHGGKSVPIVKNGDTTKMEEGEHFAIETFGSTGRGYVTAGGEVSHYARSAEDHQ
VMPTLDSAKNLLKTIDRNFGTLPFCRRYLDRLGQEKYLFALNNLVRHGLVQDYPPLND
IPGSYTAQFEHTILLHAHKKEVVSKGDDY"
gene 48825..49358
/gene="MRP21"
/locus_tag="YBL090W"
/gene_synonym="MRP50"
/db_xref="GeneID:852188"
mRNA 48825..49358
/gene="MRP21"
/locus_tag="YBL090W"
/gene_synonym="MRP50"
/product="mitochondrial 37S ribosomal protein MRP21"
/transcript_id="NM_001178330.1"
/db_xref="GI:296142582"
/db_xref="GeneID:852188"
CDS 48825..49358
/gene="MRP21"
/locus_tag="YBL090W"
/gene_synonym="MRP50"
/note="Mitochondrial ribosomal protein of the small
subunit; MRP21 exhibits genetic interactions with
mutations in the COX2 and COX3 mRNA 5'-untranslated leader
sequences"
/codon_start=1
/product="mitochondrial 37S ribosomal protein MRP21"
/protein_id="NP_009463.1"
/db_xref="GI:6319381"
/db_xref="SGD:S000000186"
/db_xref="GeneID:852188"
/translation="MLKSTLRLSRISLRRGFTTIDCLRQQNSDIDKIILNPIKLAQGS
NSDRGQTSKSKTDNADILSMEIPVDMMQSAGRINKRELLSEAEIARSSVENAQMRFNS
GKSIIVNKNNPAESFKRLNRIMFENNIPGDKRSQRFYMKPGKVAELKRSQRHRKEFMM
GFKRLIEIVKDAKRKGY"
gene 49574..50953
/gene="AVT5"
/locus_tag="YBL089W"
/db_xref="GeneID:852189"
mRNA 49574..50953
/gene="AVT5"
/locus_tag="YBL089W"
/product="Avt5p"
/transcript_id="NM_001178329.1"
/db_xref="GI:296142583"
/db_xref="GeneID:852189"
CDS 49574..50953
/gene="AVT5"
/locus_tag="YBL089W"
/note="Putative transporter; member of a family of seven
S. cerevisiae genes (AVT1-7) related to vesicular
GABA-glycine transporters; AVT5 has a paralog, AVT6, that
arose from the whole genome duplication"
/codon_start=1
/product="Avt5p"
/protein_id="NP_009464.2"
/db_xref="GI:37362614"
/db_xref="SGD:S000000185"
/db_xref="GeneID:852189"
/translation="MPSNVRSGVLTLLHTACGAGVLAMPFAFKPFGLMPGLITLTFCG
ICSLCGLLLQTRIAKYVPKSENASFAKLTQLINPSISVVFDFAIAVKCFGVGVSYLII
VGDLVPQIVQSIFYRNDDNMSGSQEHHMFLDRRLYITLIIVFVISPLCFKRSLNSLRY
ASMIAIVSVAYLSGLIIYHFVNRHQLERGQVYFMVPHGDSQSHSPLTTLPIFVFAYTC
HHNMFSVINEQVDKSFKVIRRIPIFAIVLAYFLYIIIGGTGYMTFGENIVGNILTLYP
NSISTTIGRLAMLLLVMLAFPLQCHPCRSSVKNIIIFIENFRKGKLYDNRASFIPLDN
FNSEDPQEAPTQQNNEEPNLRSESLRHINIITLCILLFSYLLAISITSLAKVLAIVGA
TGSTSISFILPGLFGYKLIGSEFTGTNERVPTSIKIFKYLSLSLFIWGIAVMVASLSA
IVFLGTSSH"
gene complement(51019..59382)
/gene="TEL1"
/locus_tag="YBL088C"
/db_xref="GeneID:852190"
mRNA complement(51019..59382)
/gene="TEL1"
/locus_tag="YBL088C"
/product="Tel1p"
/transcript_id="NM_001178328.2"
/db_xref="GI:330443402"
/db_xref="GeneID:852190"
CDS complement(51019..59382)
/gene="TEL1"
/locus_tag="YBL088C"
/EC_number="2.7.11.1"
/note="Protein kinase primarily involved in telomere
length regulation; contributes to cell cycle checkpoint
control in response to DNA damage; functionally redundant
with Mec1p; regulates P-body formation induced by
replication stress; homolog of human ataxia-telangiectasia
mutated (ATM) gene, the gene responsible for ataxia
telangiectasia (AT) (OMIM 607585)"
/codon_start=1
/product="Tel1p"
/protein_id="NP_009465.2"
/db_xref="GI:330443403"
/db_xref="SGD:S000000184"
/db_xref="GeneID:852190"
/translation="MEDHGIVETLNFLSSTKIKERNNALDELTTILKEDPERIPTKAL
STTAEALVELLASEHTKYCDLLRNLTVSTTNKLSLSENRLSTISYVLRLFVEKSCERF
KVKTLKLLLAVVPELMVKDGSKSLLDAVSVHLSFALDALIKSDPFKLKFMIHQWISLV
DKICEYFQSQMKLSMVDKTLTNFISILLNLLALDTVGIFQVTRTITWTVIDFLRLSKK
ENGNTRLIMSLINQLILKCHCFSVIDTLMLIKEAWSYNLTIGCTSNELVQDQLSLFDV
MSSELMNHKLPYMIGQENYVEELRSESLVSLYREYILLRLSNYKPQLFTVNHVEFSYI
RGSRDKNSWFALPDFRLRDRGGRSVWLKILGITKSLLTYFALNRKNENYSLLFKRRKC
DSDIPSILRISDDMDTFLIHLLEENSSHEFEVLGLQLCSFYGTLQDFTKSFAEQLKEL
LFSKFEKIQCFNWVCFSFIPLLSQKECELSNGDMARLFKVCLPLVKSNESCQLSCLLL
ANSIKFSKQLLSDEKTINQIYDLYELSDILGPILVTNESFMLWGYLQYVGKDFQSMNG
ISSADRIFEWLKSKWNQLRGTDAKQDQFCNFISWLGNKYDPENPFNDKKGEGANPVSL
CWDESHKIWQHFQEQREFLLGVKPEEKSECFNTPFFNLPKVSLDLTRYNEILYRLLEN
IESDAFSSPLQKFTWVAKLIQIVDNLCGDSTFSEFIAAYKRTTLITIPQLSFDSQNSY
QSFFEEVLSIRTINVDHLVLDKINMKEIVNDFIRMQKNKSQTGTSAINYFEASSEDTT
QNNSPYTIGGRFQKPLHSTIDKAVRAYLWSSRNKSISERLVAILEFSDCVSTDVFISY
LGTVCQWLKQAIGEKSSYNKILEEFTEVLGEKLLCNHYSSSNQAMLLLTSYIEAIRPQ
WLSYPEQPLNSDCNDILDWIISRFEDNSFTGVAPTVNLSMLLLSLLQNHDLSHGSIRG
GKQRVFATFIKCLQKLDSSNIINIMNSISSYMAQVSYKNQSIIFYEIKSLFGPPQQSI
EKSAFYSLAMSMLSLVSYPSLVFSLEDMMTYSGFNHTRAFIQQALNKITVAFRYQNLT
ELFEYCKFDLIMYWFNRTKVPTSKLEKEWDISLFGFADIHEFLGRYFVEISAIYFSQG
FNQKWILDMLHAITGNGDAYLVDNSYYLCIPLAFISGGVNELIFDILPQISGKTTVKY
HKKYRLLMLKWIIRFTDLGSLTELRSTVEKLFPTSYLSPYLFENSSVSMRYQYPLHIP
LALGATLVQTQFAHEKNNTHEFKLLFLSVITDLEKTSTYIGKLRCARELKYLFVLYEN
VLVKSSTLNFIIIRLSKFLIDTQIHDEVITIFSSLLNLADKNTFEIEPSLPNLFCKIF
IYLRENKQLSPSFQQAIKLLEHRDLIKIKTWKYCLDAIFGNIVQDDIYENTELLDASD
CGVDDVVLVSLLFSYARRPVASKIGCSLSKAAAINILKHHVPKEYLSKNFKLWFAALS
RRILQQEVQRERSTNFNNEVHLKNFEMVFRHPEQPHMIYQRISTFNKEAELYDSTEVF
FISECILTYLVGYSIGNSESEFCFRDNIMNENKDKVAPLDKDVLNAIYPLANNFGMES
FICDTYLSVNEPYNCWLSKFARSLIHQISFNIPPIVCLYPLCKGSTAFCELVLTDLFF
LSTTYDPKSCLNWSNRIFTQIAMLLHVKDSEIKLKMLFNVIKMIRMGSRCKERNCLRI
YSSLDLQEICQISLKIKEFKFGYLLFEEMNMPNIREMNINTLQKIYECINDGDFLAGL
PVPHSIEGVLNSINRIDSDTWKRFLFNNADFDANYTTSLEEEKESLIKATEDSGFYGL
TSLLESRLSGSSDVYKWNLELGDWKLLTPKVVDSKAKGLYYAIKNLPQDVGFAEKSLE
KSLLTIFDSRQHFISQTEWMDTLNAIIEFIKIAAIPQDVTSFPQTLMSIMKADKERLN
TIDFYDHKTTLKSRHTLMNVLSRNSLDENVKCSKYLRLGSIIQLANYVQLAIANGAPQ
DALRNATLMSKTVKNIAKLYDDPSVVSQIEKLASFTSANALWESREYKAPVMIMRDLL
AQNEKNISESILYDDFKLLINVPMDQIKARLVKWSSESRLEPAAAIYEKIIVNWDINV
EDHESCSDVFYTLGSFLDEQAQKLRSNGEIEDREHRSYTGKSTLKALELIYKNTKLPE
NERKDAKRHYNRVLLQYNRDSEVLKALLLQKEKFLWHALHFYLNTLVFSNRYDNDIID
KFCGLWFENDDNSKINQLLYKEIGTIPSWKFLPWVNQIASKISMEENEFQKPLQLTMK
RLLYKLPYDSLYSVMSILLYEKQSNKDTNISQKIQAVKKILLELQGYDRGAFAKKYLL
PVQEFCEMSVELANLKFVQNTKTLRLANLKIGQYWLKQLNMEKLPLPTSNFTVKSSAD
GRKARPYIVSVNETVGITTTGLSLPKIVTFNISDGTTQKALMKGSNDDLRQDAIMEQV
FQQVNKVLQNDKVLRNLDLGIRTYKVVPLGPKAGIIEFVANSTSLHQILSKLHTNDKI
TFDQARKGMKAVQTKSNEERLKAYLKITNEIKPQLRNFFFDSFPDPLDWFEAKKTYTK
GVAASSIVGYILGLGDRHLNNILLDCSTGEPIHIDLGIAFDQGKLLPIPELVPFRLTR
DIVDGFGVTGVDGLFRRSCERVYAVLRKDYVKVMCVLNILKWDPLYSWVMSPVKKYEH
LFEEEHEITNFDNVSKFISNNDRNENQESYRALKGVEEKLMGNGLSVESSVQDLIQQA
TDPSNLSVIYMGWSPFY"
gene complement(59822..60739)
/gene="RPL23A"
/locus_tag="YBL087C"
/db_xref="GeneID:852191"
mRNA complement(join(59822..60193,60698..60739))
/gene="RPL23A"
/locus_tag="YBL087C"
/product="ribosomal 60S subunit protein L23A"
/transcript_id="NM_001178327.1"
/db_xref="GI:296142585"
/db_xref="GeneID:852191"
CDS complement(join(59822..60193,60698..60739))
/gene="RPL23A"
/locus_tag="YBL087C"
/note="Ribosomal 60S subunit protein L23A; homologous to
mammalian ribosomal protein L23 and bacterial L14; RPL23A
has a paralog, RPL23B, that arose from the whole genome
duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L23A"
/protein_id="NP_009466.1"
/db_xref="GI:6319384"
/db_xref="SGD:S000000183"
/db_xref="GeneID:852191"
/translation="MSGNGAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGS
RLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVI
ANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV"
gene complement(61202..62602)
/locus_tag="YBL086C"
/db_xref="GeneID:852192"
mRNA complement(61202..62602)
/locus_tag="YBL086C"
/product="hypothetical protein"
/transcript_id="NM_001178326.1"
/db_xref="GI:296142586"
/db_xref="GeneID:852192"
CDS complement(61202..62602)
/locus_tag="YBL086C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cell periphery"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009467.1"
/db_xref="GI:6319385"
/db_xref="SGD:S000000182"
/db_xref="GeneID:852192"
/translation="MPFNHNSKAKRPKFLLDLQIKELVNIPQSSGYCYTKWRLKDGTG
TSGHKVALDGEHQTTSTQSRGTTKHVHVQHHRAQWNYSLDKPILVKLHLDKNGRFLKK
ILVLDVFFEFADANSSLTSSSSPNGKVKKTTYANATALTATGNNSYSQKITGKLLLGT
VDIDITEYVKEDETPTTNRFLLKHSKVNSIINVSLQLKLVRGSYEDFNISKSFTNGQL
ANYRPGINTILDNTSELSSPTSTTNQMSPKNTFSNFNGIGTTVAKPGTNATGNSTSIK
SPTSTNHKSSEMTTKPGLSTTISSSMSPLIESLYQKTFKLPWDPRPGEFTPRECVEDI
LQGGNGWAKNEKGINLIDLQALRLNEMEEEYYNPNYGNNLGNKASSWPPNPSDDGYST
MGKREYLEKKQNWSHMSRAQRAKLRTHNDEDNENTANDKGSDKDNNSVEDNNPTDFLT
DRIRENKNWSIITPSG"
rep_origin 63193..63427
/note="ARS202;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118344"
gene 63876..66818
/gene="BOI1"
/locus_tag="YBL085W"
/gene_synonym="BOB1; GIN7"
/db_xref="GeneID:852193"
mRNA 63876..66818
/gene="BOI1"
/locus_tag="YBL085W"
/gene_synonym="BOB1; GIN7"
/product="Boi1p"
/transcript_id="NM_001178325.1"
/db_xref="GI:296142587"
/db_xref="GeneID:852193"
CDS 63876..66818
/gene="BOI1"
/locus_tag="YBL085W"
/gene_synonym="BOB1; GIN7"
/note="Protein implicated in polar growth; functionally
redundant with Boi2p; interacts with bud-emergence protein
Bem1p; contains an SH3 (src homology 3) domain and a PH
(pleckstrin homology) domain; relocalizes from bud neck to
cytoplasm upon DNA replication stress"
/codon_start=1
/product="Boi1p"
/protein_id="NP_009468.1"
/db_xref="GI:6319386"
/db_xref="SGD:S000000181"
/db_xref="GeneID:852193"
/translation="MSLEGNTLGKGAKSFPLYIAVNQYSKRMEDELNMKPGDKIKVIT
DDGEYNDGWYYGRNLRTKEEGLYPAVFTKRIAIEKPENLHKSPTQESGNSGVKYGNLN
DSASNIGKVSSHQQENRYTSLKSTMSDIDKALEELRSGSVEQEVSKSPTRVPEVSTPQ
LQDEQTLIQEKTRNEENTTHDSLFSSTADLNLSSESLKNISKSNISTKSLEPSSESVR
QLDLKMAKSWSPEEVTDYFSLVGFDQSTCNKFKEHQVSGKILLELELEHLKELEINSF
GIRFQIFKEIRNIKSAIDSSSNKLDADYSTFAFENQAAQLMPAATVNRDEIQQQISSK
CNKLSSESSDRKSSSVTTELQRPSSVVVNPNFKLHDPAEQILDMTEVPNLFADKDIFE
SPGRAPKPPSYPSPVQPPQSPSFNNRYTNNNARFPPQTTYPPKNKNPTVYSNGLIPNS
STSSDNSTGKFKFPAMNGHDSNSRKTTLTSATIPSINTVNTDESLPAISNISSNATSH
HPNRNSVVYNNHKRTESGSSFVDLFNRISMLSPVKSSFDEEETKQPSKASRAVFDSAR
RKSSYGHSRDASLSEMKKHRRNSSILSFFSSKSQSNPTSPTKQTFTIDPAKMTSHSRS
QSNSYSHARSQSYSHSRKHSLVTSPLKTSLSPINSKSNIALAHSETPTSSNNKEAVSQ
PSEGKHKHKHKHKSKHKHKNSSSKDGSSEEKSKKKLFSSTKESFVGSKEFKRSPSELT
QKSTKSILPRSNAKKQQTSAFTEGIRSITAKESMQTADCSGWMSKKGTGAMGTWKQRF
FTLHGTRLSYFTNTNDEKERGLIDITAHRVLPASDDDRLISLYAASLGKGKYCFKLVP
PQPGSKKGLTFTEPRVHYFAVENKSEMKAWLSAIIKATIDIDTSVPVISSYATPTIPL
SKAQTLLEEARLQTQLRDAEEEEGRDQFGWDDTQNKRNSNYPIEQDQFETSDYLESSA
FEYPGGRL"
gene complement(67169..69445)
/gene="CDC27"
/locus_tag="YBL084C"
/gene_synonym="APC3; SNB1"
/db_xref="GeneID:852194"
mRNA complement(67169..69445)
/gene="CDC27"
/locus_tag="YBL084C"
/gene_synonym="APC3; SNB1"
/product="anaphase promoting complex subunit CDC27"
/transcript_id="NM_001178324.2"
/db_xref="GI:330443404"
/db_xref="GeneID:852194"
CDS complement(67169..69445)
/gene="CDC27"
/locus_tag="YBL084C"
/gene_synonym="APC3; SNB1"
/note="Subunit of the Anaphase-Promoting Complex/Cyclosome
(APC/C), which is a ubiquitin-protein ligase required for
degradation of anaphase inhibitors, including mitotic
cyclins, during the metaphase/anaphase transition"
/codon_start=1
/product="anaphase promoting complex subunit CDC27"
/protein_id="NP_009469.2"
/db_xref="GI:330443405"
/db_xref="SGD:S000000180"
/db_xref="GeneID:852194"
/translation="MAVNPELAPFTLSRGIPSFDDQALSTIIQLQDCIQQAIQQLNYS
TAEFLAELLYAECSILDKSSVYWSDAVYLYALSLFLNKSYHTAFQISKEFKEYHLGIA
YIFGRCALQLSQGVNEAILTLLSIINVFSSNSSNTRINMVLNSNLVHIPDLATLNCLL
GNLYMKLDHSKEGAFYHSEALAINPYLWESYEAICKMRATVDLKRVFFDIAGKKSNSH
NNNAASSFPSTSLSHFEPRSQPSLYSKTNKNGNNNINNNVNTLFQSSNSPPSTSASSF
SSIQHFSRSQQQQANTSIRTCQNKNTQTPKNPAINSKTSSALPNNISMNLVSPSSKQP
TISSLAKVYNRNKLLTTPPSKLLNNDRNHQNNNNNNNNNNNNNNNNNNNNNNNNIINK
TTFKTPRNLYSSTGRLTTSKKNPRSLIISNSILTSDYSITLPEIMYNFALILRSSSQY
NSFKAIRLFESQIPSHIKDTMPWCLVQLGKLHFEIINYDMSLKYFNRLKDLQPARVKD
MEIFSTLLWHLHDKVKSSNLANGLMDTMPNKPETWCCIGNLLSLQKDHDAAIKAFEKA
TQLDPNFAYAYTLQGHEHSSNDSSDSAKTCYRKALACDPQHYNAYYGLGTSAMKLGQY
EEALLYFEKARSINPVNVVLICCCGGSLEKLGYKEKALQYYELACHLQPTSSLSKYKM
GQLLYSMTRYNVALQTFEELVKLVPDDATAHYLLGQTYRIVGRKKDAIKELTVAMNLD
PKGNQVIIDELQKCHMQE"
gene complement(69751..71127)
/gene="ALG3"
/locus_tag="YBL082C"
/gene_synonym="RHK1"
/db_xref="GeneID:852196"
mRNA complement(69751..71127)
/gene="ALG3"
/locus_tag="YBL082C"
/gene_synonym="RHK1"
/product="dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol
alpha-1,3-mannosyltransferase"
/transcript_id="NM_001178322.1"
/db_xref="GI:296142589"
/db_xref="GeneID:852196"
CDS complement(69751..71127)
/gene="ALG3"
/locus_tag="YBL082C"
/gene_synonym="RHK1"
/note="Dolichol-P-Man dependent alpha(1-3)
mannosyltransferase, involved in the synthesis of
dolichol-linked oligosaccharide donor for N-linked
glycosylation of proteins"
/codon_start=1
/product="dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol
alpha-1,3-mannosyltransferase"
/protein_id="NP_009471.1"
/db_xref="GI:6319389"
/db_xref="SGD:S000000178"
/db_xref="GeneID:852196"
/translation="MEGEQSPQGEKSLQRKQFVRPPLDLWQDLKDGVRYVIFDCRANL
IVMPLLILFESMLCKIIIKKVAYTEIDYKAYMEQIEMIQLDGMLDYSQVSGGTGPLVY
PAGHVLIYKMMYWLTEGMDHVERGQVFFRYLYLLTLALQMACYYLLHLPPWCVVLACL
SKRLHSIYVLRLFNDCFTTLFMVVTVLGAIVASRCHQRPKLKKSLALVISATYSMAVS
IKMNALLYFPAMMISLFILNDANVILTLLDLVAMIAWQVAVAVPFLRSFPQQYLHCAF
NFGRKFMYQWSINWQMMDEEAFNDKRFHLALLISHLIALTTLFVTRYPRILPDLWSSL
CHPLRKNAVLNANPAKTIPFVLIASNFIGVLFSRSLHYQFLSWYHWTLPILIFWSGMP
FFVGPIWYVLHEWCWNSYPPNSQASTLLLALNTVLLLLLALTQLSGSVALAKSHLRTT
SSMEKKLN"
gene 71866..72972
/locus_tag="YBL081W"
/db_xref="GeneID:852197"
mRNA 71866..72972
/locus_tag="YBL081W"
/product="hypothetical protein"
/transcript_id="NM_001178321.1"
/db_xref="GI:296142590"
/db_xref="GeneID:852197"
CDS 71866..72972
/locus_tag="YBL081W"
/note="Non-essential hypothetical protein; null mutation
results in a decrease in plasma membrane electron
transport"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009472.1"
/db_xref="GI:6319390"
/db_xref="SGD:S000000177"
/db_xref="GeneID:852197"
/translation="MPGQIISIPFLSQNEDMDKYLLEYRSLKLLHQSSNSFQSHNAPS
HQSNYHPHYNHMKYNNTGSYYYYNNNNNSSVNPHNQAGLQSINRSIPSAPYGAYNQNR
ANDVPYMNTQKKHHRFSANNNLNQQKYKQYPQYTSNPMVTAHLKQTYPQLYYNSNVNA
HNNNNNSNNNNNNNNNSNNNNNLYNQTQFSTRYFNSNSSPSLTSSTSNSSSPYNQSTF
EYILPSTSAASTNLSSSSSNNSMHTNPTTATSTSADLINDLPVGPTSSSLISDLHSPP
TVSFLPASQTLLMSSTTSSSIGTNINPPQHSPSPSQREDFSTAPVNMSSSASLLMNDS
SLGWGSNHMNVSSSSQPASSRPFGIWNTDMSVWS"
gene complement(73070..74695)
/gene="PET112"
/locus_tag="YBL080C"
/db_xref="GeneID:852198"
mRNA complement(73070..74695)
/gene="PET112"
/locus_tag="YBL080C"
/product="glutamyl-tRNA(Gln) amidotransferase subunit
PET112"
/transcript_id="NM_001178320.2"
/db_xref="GI:330443406"
/db_xref="GeneID:852198"
CDS complement(73070..74695)
/gene="PET112"
/locus_tag="YBL080C"
/EC_number="6.3.5.-"
/note="Subunit of the trimeric GatFAB
AmidoTransferase(AdT) complex; involved in the formation
of Q-tRNAQ; mutation is functionally complemented by the
bacterial GatB ortholog"
/codon_start=1
/product="glutamyl-tRNA(Gln) amidotransferase subunit
PET112"
/protein_id="NP_009473.2"
/db_xref="GI:330443407"
/db_xref="SGD:S000000176"
/db_xref="GeneID:852198"
/translation="MLRLARFYSLARTKAIHSHGAPFRPEYALKCGLEIHTQLNTKNK
LFSQSTNSATSLVDAPNHHTSYYDIALPGTQPVLNLEAILFAMKLSLALGSQVNSISQ
FDRKHYFYGDQPQGYQLTQHYRPFARGGKINLSKELDDIDESAKEIGILQLQIEQDTG
KSHYTETDKDVITLVDLNRSNVPLIELVTKPDFSDIKQVRAFIKKYQNLVRHLHISSG
DLETGAMRVDVNLSINEYARVELKNLPNTSSIINAIKYEYQRQVELISVGDTSSLMEP
ETRGWTGSSTVKLRSKETTIDYRYMPDPELPYINLAPDVISGVRGLMPQLPDDIMRIL
MKKPYQLSLKDAKILTYNSNQNDMYNHEALRSYYLDTFREFSKLAGERSNAKLPTNWI
IHEFLGDLNKLQIPLAKAKEILPPPVFAQFLKLLHEEVISATSGKMLLFHILENFEQS
NCQDLSIPDFSKLIEKFELHAINQVDPQELMDLCNDVIAQHTDDTFIRNLVTGKKKSS
LKFLIGQGMRRSQGRIKANEFEKKFKEILNIQW"
gene 75259..79767
/gene="NUP170"
/locus_tag="YBL079W"
/gene_synonym="NLE3"
/db_xref="GeneID:852199"
mRNA 75259..79767
/gene="NUP170"
/locus_tag="YBL079W"
/gene_synonym="NLE3"
/product="Nup170p"
/transcript_id="NM_001178319.1"
/db_xref="GI:296142592"
/db_xref="GeneID:852199"
CDS 75259..79767
/gene="NUP170"
/locus_tag="YBL079W"
/gene_synonym="NLE3"
/note="Subunit of the inner ring of the nuclear pore
complex (NPC); contributes to NPC assembly and
nucleocytoplasmic transport; has similarity to Nup157p;
both Nup170p and NUP157p are similar to human Nup155p"
/codon_start=1
/product="Nup170p"
/protein_id="NP_009474.1"
/db_xref="GI:6319392"
/db_xref="SGD:S000000175"
/db_xref="GeneID:852199"
/translation="MFQSFFHNNGPAAAGETFSDSRSYPLTNHQEVPRNGLNELASSA
TKAQQQPTHILNSYPITGSNPLMRASAMGATSGSINPNMSNMNEHIRVSGMGTSKPLD
LAGKYIDHLQHKDSNTPVLDERSYYNSGVDYNFSREKNGLGAFTPFEKQDVFNIPDEI
LHEFSTSQTKTDMGIFPELNRCWITIDNKLILWNINNDNEYQVVDDMKHTIQKVALVR
PKPNTFVPAVKHLLLISTTMELFMFAISLDKATNELSVFNTHLSVPVQGIDVIDIVSH
ERSGRIFFAGQASGLNIWELHYSGSDDWFNSKCSKVCLTKSALLSLLPTNMLSQIPGV
DFIQALFEDNSNGNGGFSQETITQLTIDQQRGIIYSLSSKSTIRAYVITEKSLEGPMS
IEPAYISRIIGTTTARAAPILGPKYLKIVKISSVAPEENNNLFLVALTVGGVRLYFNG
SMGRFNIEALRLESIKFPPSSVTPEVIQQELLHQQQEQAKRSFPFFSNLMSSEPVLLK
FQKKSSVLLETTKASTIISPGIFFSAVIKSSQQTHQQEKKENSSVTGTTATAGSKTVK
QQPVTLQHKLFVSVPDYGILKTHGKYVENATFLETAGPVQQIIPLSGLFNATTKPQGF
ANEFATQYTSETLRVAVLTSTSIEIYKYRTPDEIFEDLIDNPLPFVLNYGAAEACSTA
LFVTCKSNKSEKLRSNALTFLTMGIPGVVDIKPVYNRYSVSTVSSLLSKPTLSTATTN
LQQSITGFSKPSPANKEDFDLDDVILSPRFYGIALLITRLLRDIWGRHVFMTFTDNRV
TSHAFISSSDPITPSINNLKSDEISQNRNIISKVSISKDCIEYYLSSINILNEFFITY
GDSISQISAPYVLANNSNGRVIDKTEEVANQAESIAINAMIKMVQSIKEGLSFLNVLY
EESEVEGFDNQYLGFKDIISFVSLDVQKDLVKLDFKDLFAPNDKTKSLIREILLSIIN
RNITKGASIEYTATALQERCGSFCSASDILGFRAIEHLRRAKEIGLRNYDSLNYHLKN
ATALLEQIVDDLSIEKLKEAVSMMLSVNYYPKSIEFLLNIANSMDKGKLACQYVANGF
LENDDRKQYYDKRILVYDLVFDTLIKVDELAEKKQSSKTQNQISISNDDEVKLRQKSY
EAALKYNDRLFHYHMYDWLVSQNREEKLLDIETPFILPYLMEKAGSSLKISNILWVYY
SRRSKFFESAEILYRLATSNFDITLFERIEFLSRANGFCNSVSPLSQKQRIVQLASRI
QDACEVAGIQGDILSLVYTDARIDSAIKDELIKTLDGKILSTSELFNDFAVPLSYHEI
ALFIFKIADFRDHEVIMAKWDELFQSLRMEFNNTGKKEDSMNFINLLSNVLIKIGKNV
QDSEFIFPIFELFPIVCNFFYETLPKEHIVSGSIVSIFITAGVSFNKMYYILKELIET
SDSDNSVFNKEMTWLIHEWYKSDRKFRDIISYNDIIHLKEYKIDNDPIEKYVKNSGNN
LGICFYKE"
gene complement(80378..80731)
/gene="ATG8"
/locus_tag="YBL078C"
/gene_synonym="APG8; AUT7; CVT5"
/db_xref="GeneID:852200"
mRNA complement(80378..80731)
/gene="ATG8"
/locus_tag="YBL078C"
/gene_synonym="APG8; AUT7; CVT5"
/product="Atg8p"
/transcript_id="NM_001178318.1"
/db_xref="GI:296142593"
/db_xref="GeneID:852200"
CDS complement(80378..80731)
/gene="ATG8"
/locus_tag="YBL078C"
/gene_synonym="APG8; AUT7; CVT5"
/note="Component of autophagosomes and Cvt vesicles;
unique ubiquitin-like protein whose conjugation
target is the lipid phosphatidylethanolamine (PE);
Atg8p-PE is anchored to membranes, is involved in
phagophore expansion, and may mediate membrane fusion
during autophagosome formation; deconjugation of Atg8p-PE
is required for efficient autophagosome biogenesis"
/codon_start=1
/product="Atg8p"
/protein_id="NP_009475.1"
/db_xref="GI:6319393"
/db_xref="SGD:S000000174"
/db_xref="GeneID:852200"
/translation="MKSTFKSEYPFEKRKAESERIADRFKNRIPVICEKAEKSDIPEI
DKRKYLVPADLTVGQFVYVIRKRIMLPPEKAIFIFVNDTLPPTAALMSAIYQEHKDKD
GFLYVTYSGENTFGR"
gene complement(81043..84261)
/gene="ILS1"
/locus_tag="YBL076C"
/db_xref="GeneID:852202"
mRNA complement(81043..84261)
/gene="ILS1"
/locus_tag="YBL076C"
/product="isoleucine--tRNA ligase ILS1"
/transcript_id="NM_001178316.1"
/db_xref="GI:296142594"
/db_xref="GeneID:852202"
CDS complement(81043..84261)
/gene="ILS1"
/locus_tag="YBL076C"
/EC_number="6.1.1.5"
/note="Cytoplasmic isoleucine-tRNA synthetase, target of
the G1-specific inhibitor reveromycin A"
/codon_start=1
/product="isoleucine--tRNA ligase ILS1"
/protein_id="NP_009477.1"
/db_xref="GI:6319395"
/db_xref="SGD:S000000172"
/db_xref="GeneID:852202"
/translation="MSESNAHFSFPKEEEKVLSLWDEIDAFHTSLELTKDKPEFSFFD
GPPFATGTPHYGHILASTIKDIVPRYATMTGHHVERRFGWDTHGVPIEHIIDKKLGIT
GKDDVFKYGLENYNNECRSIVMTYASDWRKTIGRLGRWIDFDNDYKTMYPSFMESTWW
AFKQLHEKGQVYRGFKVMPYSTGLTTPLSNFEAQQNYKDVNDPAVTIGFNVIGQEKTQ
LVAWTTTPWTLPSNLSLCVNADFEYVKIYDETRDRYFILLESLIKTLYKKPKNEKYKI
VEKIKGSDLVGLKYEPLFPYFAEQFHETAFRVISDDYVTSDSGTGIVHNAPAFGEEDN
AACLKNGVISEDSVLPNAIDDLGRFTKDVPDFEGVYVKDADKLIIKYLTNTGNLLLAS
QIRHSYPFCWRSDTPLLYRSVPAWFVRVKNIVPQMLDSVMKSHWVPNTIKEKRFANWI
ANARDWNVSRNRYWGTPIPLWVSDDFEEVVCVGSIKELEELTGVRNITDLHRDVIDKL
TIPSKQGKGDLKRIEEVFDCWFESGSMPYASQHYPFENTEKFDERVPANFISEGLDQT
RGWFYTLAVLGTHLFGSVPYKNVIVSGIVLAADGRKMSKSLKNYPDPSIVLNKYGADA
LRLYLINSPVLKAESLKFKEEGVKEVVSKVLLPWWNSFKFLDGQIALLKKMSNIDFQY
DDSVKSDNVMDRWILASMQSLVQFIHEEMGQYKLYTVVPKLLNFIDELTNWYIRFNRR
RLKGENGVEDCLKALNSLFDALFTFVRAMAPFTPFLSESIYLRLKEYIPEAVLAKYGK
DGRSVHFLSYPVVKKEYFDEAIETAVSRMQSVIDLGRNIREKKTISLKTPLKTLVILH
SDESYLKDVEALKNYIIEELNVRDVVITSDEAKYGVEYKAVADWPVLGKKLKKDAKKV
KDALPSVTSEQVREYLESGKLEVAGIELVKGDLNAIRGLPESAVQAGQETRTDQDVLI
IMDTNIYSELKSEGLARELVNRIQKLRKKCGLEATDDVLVEYELVKDTIDFEAIVKEH
FDMLSKTCRSDIAKYDGSKTDPIGDEEQSINDTIFKLKVFKL"
gene complement(84499..86448)
/gene="SSA3"
/locus_tag="YBL075C"
/gene_synonym="YG106"
/db_xref="GeneID:852203"
mRNA complement(84499..86448)
/gene="SSA3"
/locus_tag="YBL075C"
/gene_synonym="YG106"
/product="Ssa3p"
/transcript_id="NM_001178315.1"
/db_xref="GI:296142595"
/db_xref="GeneID:852203"
CDS complement(84499..86448)
/gene="SSA3"
/locus_tag="YBL075C"
/gene_synonym="YG106"
/note="ATPase involved in protein folding and the response
to stress; plays a role in SRP-dependent cotranslational
protein-membrane targeting and translocation; member of
the heat shock protein 70 (HSP70) family; localized to the
cytoplasm"
/codon_start=1
/product="Hsp70 family ATPase SSA3"
/protein_id="NP_009478.1"
/db_xref="GI:6319396"
/db_xref="SGD:S000000171"
/db_xref="GeneID:852203"
/translation="MSRAVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTD
TERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQ
VEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAG
TIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNVLIFDLGGGTFDVSLLSIDEGVFEVK
ATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSS
QTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVL
VGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQDLLLL
DVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKD
NNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRL
SKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGEDDAK
RLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIMTKFYGAGAGAGPGAGESGG
FPGSMPNSGATGGGEDTGPTVEEVD"
gene complement(86722..87789)
/gene="AAR2"
/locus_tag="YBL074C"
/db_xref="GeneID:852205"
mRNA complement(86722..87789)
/gene="AAR2"
/locus_tag="YBL074C"
/product="Aar2p"
/transcript_id="NM_001178314.1"
/db_xref="GI:296142596"
/db_xref="GeneID:852205"
CDS complement(86722..87789)
/gene="AAR2"
/locus_tag="YBL074C"
/note="Component of the U5 snRNP, required for splicing of
U3 precursors; originally described as a splicing factor
specifically required for splicing pre-mRNA of the MATa1
cistron"
/codon_start=1
/product="Aar2p"
/protein_id="NP_009479.1"
/db_xref="GI:6319398"
/db_xref="SGD:S000000170"
/db_xref="GeneID:852205"
/translation="MNTVPFTSAPIEVTIGIDQYSFNVKENQPFHGIKDIPIGHVHVI
HFQHADNSSMRYGYWFDCRMGNFYIQYDPKDGLYKMMEERDGAKFENIVHNFKERQMM
VSYPKIDEDDTWYNLTEFVQMDKIRKIVRKDENQFSYVDSSMTTVQENELLKSSLQKA
GSKMEAKNEDDPAHSLNYTVINFKSREAIRPGHEMEDFLDKSYYLNTVMLQGIFKNSS
NYFGELQFAFLNAMFFGNYGSSLQWHAMIELICSSATVPKHMLDKLDEILYYQIKTLP
EQYSDILLNERVWNICLYSSFQKNSLHNTEKIMENKYPELLGKDNEDDALIYGISDEE
RDDEDDEHNPTIVGGLYYQRP"
gene 88190..88277
/locus_tag="snR56"
/db_xref="GeneID:9164868"
ncRNA 88190..88277
/locus_tag="snR56"
/ncRNA_class="snoRNA"
/product="SNR56"
/note="C/D box small nucleolar RNA (snoRNA), guides
2'-O-methylation of small subunit (SSU) rRNA at position
G1428"
/db_xref="SGD:S000006447"
/db_xref="GeneID:9164868"
gene complement(88523..89125)
/gene="RPS8A"
/locus_tag="YBL072C"
/db_xref="GeneID:852206"
mRNA complement(88523..89125)
/gene="RPS8A"
/locus_tag="YBL072C"
/product="ribosomal 40S subunit protein S8A"
/transcript_id="NM_001178312.1"
/db_xref="GI:296142597"
/db_xref="GeneID:852206"
CDS complement(88523..89125)
/gene="RPS8A"
/locus_tag="YBL072C"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S8, no
bacterial homolog; RPS8A has a paralog, RPS8B, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S8A"
/protein_id="NP_009481.1"
/db_xref="GI:6319399"
/db_xref="SGD:S000000168"
/db_xref="GeneID:852206"
/translation="MGISRDSRHKRSATGAKRAQFRKKRKFELGRQPANTKIGAKRIH
SVRTRGGNKKYRALRIETGNFSWASEGISKKTRIAGVVYHPSNNELVRTNTLTKAAIV
QIDATPFRQWFEAHYGQTLGKKKNVKEEETVAKSKNAERKWAARAASAKIESSVESQF
SAGRLYACISSRPGQSGRCDGYILEGEELAFYLRRLTAKK"
gene complement(89458..89556)
/locus_tag="YBL071C-B"
/db_xref="GeneID:1466440"
mRNA complement(89458..89556)
/locus_tag="YBL071C-B"
/product="hypothetical protein"
/transcript_id="NM_001184584.1"
/db_xref="GI:296142598"
/db_xref="GeneID:1466440"
CDS complement(89458..89556)
/locus_tag="YBL071C-B"
/note="hypothetical protein; identified by gene-trapping,
microarray-based expression analysis, and genome-wide
homology searching"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878044.1"
/db_xref="GI:33438762"
/db_xref="SGD:S000028597"
/db_xref="GeneID:1466440"
/translation="MELFHIRYLQAYLKVIGNYTCHLLFGTHKKTL"
gene 89978..90226
/gene="KTI11"
/locus_tag="YBL071W-A"
/gene_synonym="DPH3"
/db_xref="GeneID:852207"
mRNA 89978..90226
/gene="KTI11"
/locus_tag="YBL071W-A"
/gene_synonym="DPH3"
/product="Kti11p"
/transcript_id="NM_001184454.1"
/db_xref="GI:296142599"
/db_xref="GeneID:852207"
CDS 89978..90226
/gene="KTI11"
/locus_tag="YBL071W-A"
/gene_synonym="DPH3"
/note="Zn-ribbon protein that co-purifies with Dph1 and
Dph2 in a complex required for synthesis of diphthamide on
translation factor eEF2 and with Elongator subunits Iki3p,
Elp2p, and Elp3p involved in modification of wobble
nucleosides in tRNAs"
/codon_start=1
/product="Kti11p"
/protein_id="NP_660100.1"
/db_xref="GI:21648335"
/db_xref="SGD:S000007587"
/db_xref="GeneID:852207"
/translation="MSTYDEIEIEDMTFEPENQMFTYPCPCGDRFQIYLDDMFEGEKV
AVCPSCSLMIDVVFDKEDLAEYYEEAGIHPPEPIAAAA"
gene 90741..92030
/gene="AST1"
/locus_tag="YBL069W"
/db_xref="GeneID:852209"
mRNA 90741..92030
/gene="AST1"
/locus_tag="YBL069W"
/product="Ast1p"
/transcript_id="NM_001178309.1"
/db_xref="GI:296142600"
/db_xref="GeneID:852209"
CDS 90741..92030
/gene="AST1"
/locus_tag="YBL069W"
/note="Lipid raft associated protein; interacts with the
plasma membrane ATPase Pma1p and has a role in its
targeting to the plasma membrane by influencing its
incorporation into lipid rafts; sometimes classified in
the medium-chain dehydrogenase/reductases (MDRs)
superfamily; AST1 has a paralog, AST2, that arose from the
whole genome duplication"
/codon_start=1
/product="Ast1p"
/protein_id="NP_009484.2"
/db_xref="GI:14270687"
/db_xref="SGD:S000000165"
/db_xref="GeneID:852209"
/translation="MAKDILKNQDPKLQAMIVEHSAPAPKEIPMDAPVLKRVARPLRH
VKFIPIKSLIFHTKTGPMDFSYEKKIKTPIPKNKIVVRVSNVGLNPVDMKIRNGYTSS
IYGEIGLGREYSGVITEVGENLNYAWHVGDEVYGIYYHPHLAVGCLQSSILVDPKVDP
ILLRPESVSAEEAAGSLFCLATGYNILNKLSKNKYLKQDSNVLINGGTSSVGMFVIQL
LKRHYKLQKKLVIVTSANGPQVLQEKFPDLADEMIFIDYLTCRGKSSKPLRKMLEEKK
ISQYDPVEDKETILNYNEGKFDVVLDFVGGYDILSHSSSLIHGGGAYVTTVGDYVANY
KEDIFDSWDNPSANARKMFGSIIWSYNYTHYYFDPNAKTASANNDWIEQCGDFLKNGT
VKCVVDKVYDWKDHKEAFSYMATQRAQGKLIMNVEKF"
gene 92414..93394
/gene="PRS4"
/locus_tag="YBL068W"
/db_xref="GeneID:852211"
mRNA 92414..93394
/gene="PRS4"
/locus_tag="YBL068W"
/product="ribose phosphate diphosphokinase subunit PRS4"
/transcript_id="NM_001178308.2"
/db_xref="GI:330443408"
/db_xref="GeneID:852211"
CDS 92414..93394
/gene="PRS4"
/locus_tag="YBL068W"
/EC_number="2.7.6.1"
/note="5-phospho-ribosyl-1(alpha)-pyrophosphate
synthetase, synthesizes PRPP, which is required for
nucleotide, histidine, and tryptophan biosynthesis; one of
five related enzymes, which are active as heteromultimeric
complexes; PRS4 has a paralog, PRS2, that arose from the
whole genome duplication"
/codon_start=1
/product="ribose phosphate diphosphokinase subunit PRS4"
/protein_id="NP_009485.3"
/db_xref="GI:330443409"
/db_xref="SGD:S000000164"
/db_xref="GeneID:852211"
/translation="MNSESREDMAINSIKLLAGNSHPDLAEQISKKLGIPLSKVGVYQ
YSNKETSVTIGESLRDEDVYIIQTGIGEQEINDFLMELLILIHACKIASARKITTVIP
NFPYARQDKKDKSRAPITAKLVANLLQTAGADHVITMDLHASQIQGFFHIPVDNLYAE
PSVLNYIRTKTDFDNAILVSPDAGGAKRVAALADKLDLNFALIHKERQKANEVSKMVL
VGDVTNKSCLLVDDMADTCGTLVKACDTLMEHGAKEVIAIVTHGIFSGSAREKLRNSR
LSRIVCTNTVPVDLDLPIADQIDISPTFAEAIRRLHNGESVSYLFTHAPV"
gene complement(93639..95882)
/gene="UBP13"
/locus_tag="YBL067C"
/db_xref="GeneID:852212"
mRNA complement(93639..95882)
/gene="UBP13"
/locus_tag="YBL067C"
/product="Ubp13p"
/transcript_id="NM_001178307.2"
/db_xref="GI:330443410"
/db_xref="GeneID:852212"
CDS complement(93639..95882)
/gene="UBP13"
/locus_tag="YBL067C"
/EC_number="3.1.2.15"
/note="Putative ubiquitin carboxyl-terminal hydrolase;
ubiquitin-specific protease that cleaves ubiquitin-protein
fusions; UBP13 has a paralog, UBP9, that arose from the
whole genome duplication"
/codon_start=1
/product="Ubp13p"
/protein_id="NP_009486.3"
/db_xref="GI:330443411"
/db_xref="SGD:S000000163"
/db_xref="GeneID:852212"
/translation="MIRRWLTISKSGKKKKAVNDTITEEVEKVDFKPVNHDINDELCY
SESSDNPSSSLFVSNLDTKETFLNEDNNLQISSGLDYSSETCNQGSNYSQDGIFYISN
AKAINAYGGIITQGPEAPILAMKVSDSMPYGDGSNKVFGYENFGNTCYCNSVLQCLYN
LSSLRENILQFPKKSRESDQPRKKEMRGKKPRIFTEASFEKSIAGTNGHLPNPKPQSV
DDGKPTPVNSVNSNTAGPSEKKSKFFKSFSAKHVQDNNKKEGSPAILTTGKPSSRPQD
APPLIVETPNEPGAPSRLSFENVTDRPPDVPRKIIVGRVLNYENPSRGSSNSNNLDLK
GESNSSLSTPLDKKDTRRSSSSSQISPEHRKKSALIRGPVLNIDHSLNGSDKATLYSS
LRDIFECITENTYLTGVVSPSSFVDVLKRENVLFNTTMHQDAHEFFNFLLNELSEYIE
RENKKIAASDINSDSEPSKSKNFISDLFQGTLTNQIKCLTCDNITSRDEPFLDFPIEV
QGDEETDIQEILKSYHQREMLNGSNKFYCDECCGLQEAERLVGLKQLPDTLTLHLKRF
KYSEKQNCNIKLFNNIHYPLTLNVCSSINSKVCQKYELAGIVVHMGGGPQHGHYVSLC
KHEKFGWLLFDDETVEAVKEETVLEFTGESPNMATAYVLFYKAMYSNAVEKNDRENMA
KEQDDNIDNLIKYDDWLRTCNSGQKKKEELPIADDLDTAIDDSFVSNTPIKSSKKKSR
MFSFRKS"
gene complement(96669..100115)
/gene="SEF1"
/locus_tag="YBL066C"
/db_xref="GeneID:852214"
mRNA complement(96669..100115)
/gene="SEF1"
/locus_tag="YBL066C"
/product="Sef1p"
/transcript_id="NM_001178306.1"
/db_xref="GI:296142603"
/db_xref="GeneID:852214"
CDS complement(96669..100115)
/gene="SEF1"
/locus_tag="YBL066C"
/note="Putative transcription factor, has homolog in
Kluyveromyces lactis"
/codon_start=1
/product="Sef1p"
/protein_id="NP_009487.2"
/db_xref="GI:50593117"
/db_xref="SGD:S000000162"
/db_xref="GeneID:852214"
/translation="MVKDNRDSDQDQDFSSAHMKRQPEQQQLQQHQFPSKKQRISHHD
DSHQINHRPVTSCTHCRQHKIKCDASQNFPHPCSRCEKIGLHCEINPQFRPKKGSQLQ
LLRQDVDEIKSKLDTLLANDSVFVHLLQQIPMGNSLLNKLNLHPTPTPGTIIPNPDSS
PSSGSPTSSAAQRDSKVSVQTYLSREPQLLQANQGSNTNKFKANNEASSHMTLRASSL
AQDSKGLVATEPNKLPPLLNDSALPNNSKESLPPALQMAFYKNNSAGNTPNGPFSPIQ
KTYSPHTTSTTVTTTTNQPPFAATSHVATNNNADRTKTPVVATTTTMPLLPSPHANVD
EFVLGDISISIEKANRLHHIFVTRYLPYFPIMYSNNATELYSQSQLLFWTVMLTACLS
DPEPTMYCKLSSLIKQLAIETCWIRTPRSTHISQALLILCIWPLPNQKVLDDCSYRFV
GLAKSLSYQLGLHRGEFISEFTRTQTSMPNAEKWRTRTWLGIFFAELCWASILGLPPT
SQTDYLLEKALSCGDEESEEDNNDSIDNNNNDKRNKKDEPHVESKYKLPGSFRRLLSL
ANFQAKLSHIIGSSTSSPDGLLEPKYRAETLSILGKELDLLAKTLNFQSDDTVNIYFL
YVKLTVCCFAFLPETPPTDQIPYVTEAYLTATKIVTLLNNLLETHQLIELPIYIRQAA
TFSALILFKLQLTPLLPDKYFDSARQSVVTIHRLYRNQLTAWATSVENDISRTASMLE
KLNFVLIMHPEVFVEEDGIISRMRSHLTGSLFYDLVWCVHEARRREMDPEYNKQALEK
AAKKRKFSSNGIYNGTSSTGGITDRKLYPLPLYNHISRDDFETVTKTTPSGTTVTTLV
PTKNALKQAEKLAKTNNGDSDGSIMEINGIPLSMLGETGSVKFQSLFANTSNSNDYNN
NRTLLDASNDISIPSNSIYPVASVPASNNNPQSTKVDYYSNGPSVIPDLSMKRSVSTP
VNHFPASVPGLRNHPVGNLSNNVTLGIDHPIPREHSNLQNVTMNYNNQFSNANAIGRS
QSSMSHSRTPIASKSNNMTDLHSVVSDPGSSKSTAYPPLSLFSKSNDINSNKTNQRFS
TGTNTVTSSNFQTIDNENNVKTPGNKLTDFFQQQSAGWIEGNSSNDDFFGWFDMNMEQ
GF"
gene complement(100371..101156)
/gene="PRX1"
/locus_tag="YBL064C"
/db_xref="GeneID:852215"
mRNA complement(100371..101156)
/gene="PRX1"
/locus_tag="YBL064C"
/product="Prx1p"
/transcript_id="NM_001178304.1"
/db_xref="GI:296142604"
/db_xref="GeneID:852215"
CDS complement(100371..101156)
/gene="PRX1"
/locus_tag="YBL064C"
/EC_number="1.11.1.15"
/note="Mitochondrial peroxiredoxin with thioredoxin
peroxidase activity; has a role in reduction of
hydroperoxides; reactivation requires Trr2p and
glutathione; induced during respiratory growth and
oxidative stress; phosphorylated; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Prx1p"
/protein_id="NP_009489.1"
/db_xref="GI:6319407"
/db_xref="SGD:S000000160"
/db_xref="GeneID:852215"
/translation="MFSRICSAQLKRTAWTLPKQAHLQSQTIKTFATAPILCKQFKQS
DQPRLRINSDAPNFDADTTVGKINFYDYLGDSWGVLFSHPADFTPVCTTEVSAFAKLK
PEFDKRNVKLIGLSVEDVESHEKWIQDIKEIAKVKNVGFPIIGDTFRNVAFLYDMVDA
EGFKNINDGSLKTVRSVFVIDPKKKIRLIFTYPSTVGRNTSEVLRVIDALQLTDKEGV
VTPINWQPADDVIIPPSVSNDEAKAKFGQFNEIKPYLRFTKSK"
gene 101886..105221
/gene="KIP1"
/locus_tag="YBL063W"
/gene_synonym="CIN9"
/db_xref="GeneID:852216"
mRNA 101886..105221
/gene="KIP1"
/locus_tag="YBL063W"
/gene_synonym="CIN9"
/product="Kip1p"
/transcript_id="NM_001178303.1"
/db_xref="GI:296142605"
/db_xref="GeneID:852216"
CDS 101886..105221
/gene="KIP1"
/locus_tag="YBL063W"
/gene_synonym="CIN9"
/note="Kinesin-related motor protein required for mitotic
spindle assembly, chromosome segregation, and 2 micron
plasmid partitioning; functionally redundant with Cin8p
for chromosomal but not plasmid functions"
/codon_start=1
/product="Kip1p"
/protein_id="NP_009490.1"
/db_xref="GI:6319408"
/db_xref="SGD:S000000159"
/db_xref="GeneID:852216"
/translation="MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNN
GAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTY
QFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGD
VQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDD
DPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCN
DLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQ
EAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKI
SMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIF
ITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAII
QNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVL
QTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQM
NELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTS
INEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQL
AEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKI
HSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKIS
QTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNEN
NINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAH
SIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNEN
FPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFT
TEPILKGEETENNDILQNKKLHQ"
gene complement(105316..107406)
/gene="SKT5"
/locus_tag="YBL061C"
/gene_synonym="CAL2; CHS4; CSD4"
/db_xref="GeneID:852218"
mRNA complement(105316..107406)
/gene="SKT5"
/locus_tag="YBL061C"
/gene_synonym="CAL2; CHS4; CSD4"
/product="Skt5p"
/transcript_id="NM_001178301.1"
/db_xref="GI:296142606"
/db_xref="GeneID:852218"
CDS complement(105316..107406)
/gene="SKT5"
/locus_tag="YBL061C"
/gene_synonym="CAL2; CHS4; CSD4"
/note="Activator of Chs3p (chitin synthase III) during
vegetative growth; recruits Chs3p to the bud neck via
interaction with Bni4p; SKT5 has a paralog, SHC1, that
arose from the whole genome duplication"
/codon_start=1
/product="Skt5p"
/protein_id="NP_009492.1"
/db_xref="GI:6319410"
/db_xref="SGD:S000000157"
/db_xref="GeneID:852218"
/translation="MASSPQVHPYKKHLMQSQHINFDNRGLQFQNSSLKVGQDFSDNK
ENRENRDNEDFSTADLPKRSANQPLINEHLRAASVPLLSNDIGNSQEEDFVPVPPPQL
HLNNSNNTSLSSLGSTPTNSPSPGALRQTNSSTSLTKEQIKKRTRSVDLSHMYLLNGS
SDTQLTATNESVADLSHQMISRYLGGKNNTSLVPRLKTIEMYRQNVKKSKDPEVLFQY
AQYMLQTALTIESSNALVQDSDKEGNVSQSDLKLQFLKEAQSYLKKLSIKGYSDAQYL
LADGYSSGAFGKIENKEAFVLFQAAAKHGHIESAYRASHCLEEGLGTTRDSRKSVNFL
KFAASRNHPSAMYKLGLYSFYGRMGLPTDVNTKLNGVKWLSRAAARANELTAAAPYEL
AKIYHEGFLDVVIPDEKYAMELYIQAASLGHVPSATLLAQIYETGNDTVGQDTSLSVH
YYTQAALKGDSVAMLGLCAWYLLGAEPAFEKDENEAFQWALRAANAGLPKAQFTLGYF
YEHGKGCDRNMEYAWKWYEKAAGNEDKRAINKLRSRDGGLASIGKKQHKKNKSISTLN
LFSTVDSQTSNVGSNSRVSSKSETFFTGNPKRDREPQGLQINMNSNTNRNGIKTGSDT
SIRKSSSSAKGMSREVAEQSMAAKQEVSLSNMGSSNMIRKDFPAVKTESKKPTSLKNK
KDKQGKKKKDCVIM"
gene 107932..109995
/gene="YEL1"
/locus_tag="YBL060W"
/db_xref="GeneID:852219"
mRNA 107932..109995
/gene="YEL1"
/locus_tag="YBL060W"
/product="Yel1p"
/transcript_id="NM_001178300.1"
/db_xref="GI:296142607"
/db_xref="GeneID:852219"
CDS 107932..109995
/gene="YEL1"
/locus_tag="YBL060W"
/note="Guanine nucleotide exchange factor specific for
Arf3p; localized to the bud neck and tip; required for
localization of Arf3p to the bud neck and tip"
/codon_start=1
/product="Yel1p"
/protein_id="NP_009493.1"
/db_xref="GI:6319411"
/db_xref="SGD:S000000156"
/db_xref="GeneID:852219"
/translation="MCASLNEVKKNDTYGVSQKGYNDNFSESEGVLHGSKSMPTSMKN
MLQSPTMVNMCDILQNKEAANDEKPVIPTTDTATAGTGTEDISSTQSEETDQNSHLIA
SEILEGTFKDVSYKEYANFLGNDNNNQVLTEFVKLLSPLPSSLLETLFNLSKSIYFIA
EAQNIDRILECLSIEWIACHPNTHWKSGYKSCHIVLFSLLILNSDLHNNFQVDHKKIK
FSMVAFINNTLRALREENEYEELKIYSREHLIIEELSEYYKTLNETPLPLCTESRTSI
NISDNQSSLKRFSTLGSREFSTSNLRSVNSNSTTLYSRDGQVSVREMSAKSNKNFHNN
HPMDALYLKESFDDGLITENGSSWFMDDLILISKKSLPRKYSKRDKDQVAAPKMTSKR
NKSFFGWLKPSKTTTLIEHTSRRTSLSYLNKDSEWERVKIQVKEGRIFIFKIKPDVKD
IIQSSETDSATIDYFKDISSSYFAYSLLEAEAHVVQDNIIIGSGAMKSNVCNKNTKRK
SGNFTVSFPENINGPKLVLEFQTRSVEEAHKFMDCINFWAGRISPVPLTQFEAVSNAE
YGWSDKILTEHASLNLKNIVVSEWKPLLGLELLYEDAKDVEMVELKERLKELMNFTRQ
LGIWIDKHNEIKDKLVEIWSFDDNYFEAVMNNWNSRYLYMNNQYKKRLSYLKALQKAM
GSVQF"
gene complement(110125..110539)
/gene="CMC2"
/locus_tag="YBL059C-A"
/db_xref="GeneID:852220"
mRNA complement(join(110125..110420,110506..110539))
/gene="CMC2"
/locus_tag="YBL059C-A"
/product="Cmc2p"
/transcript_id="NM_001184440.1"
/db_xref="GI:296142608"
/db_xref="GeneID:852220"
CDS complement(join(110125..110420,110506..110539))
/gene="CMC2"
/locus_tag="YBL059C-A"
/note="Protein of the mitochondrial intermembrane space
with a role in respiratory chain complex assembly or
maintenance; contains twin Cx9C motifs that can form
coiled coil-helix-coiled-coil helix fold"
/codon_start=1
/product="Cmc2p"
/protein_id="NP_031358.1"
/db_xref="GI:6681845"
/db_xref="SGD:S000007488"
/db_xref="GeneID:852220"
/translation="MHPQLEAERFHSCLDFINALDKCHQKEYYKRIFGLCNNEKDALN
KCLKEASLNNKKRAVIESRIKRADVEKRWKKIEEEEYGEDAILKTILDRQYAKKKQES
DNDANSK"
gene 110594..111244
/locus_tag="YBL059W"
/db_xref="GeneID:852221"
mRNA join(110594..110879,110949..111244)
/locus_tag="YBL059W"
/product="hypothetical protein"
/transcript_id="NM_001178299.1"
/db_xref="GI:296142609"
/db_xref="GeneID:852221"
CDS join(110594..110879,110949..111244)
/locus_tag="YBL059W"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies; YBL059W has a paralog, YER093C-A,
that arose from the whole genome duplication"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009494.1"
/db_xref="GI:6319412"
/db_xref="SGD:S000000155"
/db_xref="GeneID:852221"
/translation="MLLDAQRFFNRSFSINVICELKHNVNTRRKFEIKDWPTIMLVSR
NDKPKISSEEVTHFIDDYKKRRKTQMTRFFGITIFTLITCRIAMKKMITAKVPLNTFQ
ANYASRTQTITHTQKSLAGSLLAATGMTLGIFGMGITGTCWSWDVSSFQELKQRLERR
ANNEFVVTNMPLDKRSQQVVDSLVKTHNSSLCK"
gene 111437..112708
/gene="SHP1"
/locus_tag="YBL058W"
/gene_synonym="UBX1"
/db_xref="GeneID:852222"
mRNA 111437..112708
/gene="SHP1"
/locus_tag="YBL058W"
/gene_synonym="UBX1"
/product="Shp1p"
/transcript_id="NM_001178298.1"
/db_xref="GI:296142610"
/db_xref="GeneID:852222"
CDS 111437..112708
/gene="SHP1"
/locus_tag="YBL058W"
/gene_synonym="UBX1"
/note="UBX (ubiquitin regulatory X) domain-containing
protein that regulates Glc7p phosphatase activity and
interacts with Cdc48p; interacts with ubiquitylated
proteins in vivo and is required for degradation of a
ubiquitylated model substrate"
/codon_start=1
/product="Shp1p"
/protein_id="NP_009495.1"
/db_xref="GI:6319413"
/db_xref="SGD:S000000154"
/db_xref="GeneID:852222"
/translation="MAEIPDETIQQFMALTNVSHNIAVQYLSEFGDLNEALNSYYASQ
TDDQKDRREEAHWNRQQEKALKQEAFSTNSSNKAINTEHVGGLCPKPGSSQGSNEYLK
RKGSTSPEPTKGSSRSGSGNNSRFMSFSDMVRGQADDDDEDQPRNTFAGGETSGLEVT
DPSDPNSLLKDLLEKARRGGQMGAENGFRDDEDHEMGANRFTGRGFRLGSTIDAADEV
VEDNTSQSQRRPEKVTREITFWKEGFQVADGPLYRYDDPANSFYLSELNQGRAPLKLL
DVQFGQEVEVNVYKKLDESYKAPTRKLGGFSGQGQRLGSPIPGESSPAEVPKNETPAA
QEQPMPDNEPKQGDTSIQIRYANGKREVLHCNSTDTVKFLYEHVTSNANTDPSRNFTL
NYAFPIKPISNDETTLKDADLLNSVVVQRWA"
gene complement(112801..113427)
/gene="PTH2"
/locus_tag="YBL057C"
/db_xref="GeneID:852223"
mRNA complement(112801..113427)
/gene="PTH2"
/locus_tag="YBL057C"
/product="Pth2p"
/transcript_id="NM_001178297.2"
/db_xref="GI:330443412"
/db_xref="GeneID:852223"
CDS complement(112801..113427)
/gene="PTH2"
/locus_tag="YBL057C"
/EC_number="3.1.1.29"
/note="One of two (see also PTH1)
mitochondrially-localized peptidyl-tRNA hydrolases;
negatively regulates the ubiquitin-proteasome pathway via
interactions with ubiquitin-like ubiquitin-associated
proteins; dispensable for cell growth"
/codon_start=1
/product="Pth2p"
/protein_id="NP_009496.2"
/db_xref="GI:330443413"
/db_xref="SGD:S000000153"
/db_xref="GeneID:852223"
/translation="MEKMTVSSNYTIALWATFTAISFAVGYQLGTSNASSTKKSSATL
LRSKEMKEGKLHNDTDEEESESEDESDEDEDIESTSLNDIPGEVRMALVIRQDLGMTK
GKIAAQCCHAALSCFRHIATNPARASYNPIMTQRWLNAGQAKITLKCPDKFTMDELYA
KAISLGVNAAVIHDAGRTQIAAGSATVLGLGPAPKAVLDQITGDLKLY"
gene 113762..115168
/gene="PTC3"
/locus_tag="YBL056W"
/db_xref="GeneID:852224"
mRNA 113762..115168
/gene="PTC3"
/locus_tag="YBL056W"
/product="Ptc3p"
/transcript_id="NM_001178296.2"
/db_xref="GI:330443414"
/db_xref="GeneID:852224"
CDS 113762..115168
/gene="PTC3"
/locus_tag="YBL056W"
/EC_number="3.1.3.16"
/note="Type 2C protein phosphatase (PP2C);
dephosphorylates Hog1p (see also Ptc2p) to limit maximal
kinase activity induced by osmotic stress;
dephosphorylates T169 phosphorylated Cdc28p (see also
Ptc2p); role in DNA damage checkpoint inactivation; PTC3
has a paralog, PTC2, that arose from the whole genome
duplication"
/codon_start=1
/product="Ptc3p"
/protein_id="NP_009497.2"
/db_xref="GI:330443415"
/db_xref="SGD:S000000152"
/db_xref="GeneID:852224"
/translation="MGQILSNPIIDKEHHSGTDCLTAFGLCAMQGWRMSMEDAHIVEP
NLLAESDEEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESFKSGMLEQCLIDTFLA
TDVELLKDEKLKDDHSGCTATVILVSQLKKLLICANSGDSRTVLSTGGNSKAMSFDHK
PTLLSEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNTKLGPHEQVVTCVPDIIC
HNLNYDEDEFVILACDGIWDCLTSQECVDLVHYGISQGNMTLSDISSRIVDVCCSPTT
EGSGIGCDNMSISIVALLKENESESQWFERMRSKNYNIQTSFVQRRKSIFDFHDFSDD
DNEVFAITTKKLQDRLNRSKDNDDMEIDDLDTELGSSATPSKLSGEDRTGPIDLFSLE
ALLEAGIQIRQRPSSDSDGNTSYFHGASLSDMLASLSNAAAGETEPNDADDNDDNDGE
ENGKNENAKKGSKIEEIE"
gene complement(115573..116829)
/locus_tag="YBL055C"
/db_xref="GeneID:852225"
mRNA complement(115573..116829)
/locus_tag="YBL055C"
/product="3'-5'-exodeoxyribonuclease"
/transcript_id="NM_001178295.1"
/db_xref="GI:296142613"
/db_xref="GeneID:852225"
CDS complement(115573..116829)
/locus_tag="YBL055C"
/EC_number="3.1.21.-"
/note="3'-->5' exonuclease and endonuclease with a
possible role in apoptosis; has similarity to mammalian
and C. elegans apoptotic nucleases"
/codon_start=1
/product="3'-5'-exodeoxyribonuclease"
/protein_id="NP_009498.1"
/db_xref="GI:6319416"
/db_xref="SGD:S000000151"
/db_xref="GeneID:852225"
/translation="MWGILLKSSNKSCSRLWKPILTQYYSMTSTATDSPLKYYDIGLN
LTDPMFHGIYNGKQYHPADYVKLLERAAQRHVKNALVTGSSIAESQSAIELVSSVKDL
SPLKLYHTIGVHPCCVNEFADASQGDKASASIDNPSMDEAYNESLYAKVISNPSFAQG
KLKELYDLMNQQAKPHDTSFRSIGEIGLDYDRFHYSSKEMQKVFFEEQLKISCLNDKL
SSYPLFLHMRSACDDFVQILERFIAGFTDERDTFQLQKLGASSSSGFYKFHPDRKLVV
HSFTGSAIDLQKLLNLSPNIFIGVNGCSLRTEENLAVVKQIPTERLLLETDAPWCEIK
RTHASFQYLAKYQEVRDFEYPAFKSVKKNKLADKLNAEELYMVKGRNEPCNMEQVAIV
VSEVKDVDLATLIDTTWKTTCKIFGE"
gene 117589..119166
/gene="TOD6"
/locus_tag="YBL054W"
/gene_synonym="PBF1"
/db_xref="GeneID:852226"
mRNA 117589..119166
/gene="TOD6"
/locus_tag="YBL054W"
/gene_synonym="PBF1"
/product="Tod6p"
/transcript_id="NM_001178294.1"
/db_xref="GI:296142614"
/db_xref="GeneID:852226"
CDS 117589..119166
/gene="TOD6"
/locus_tag="YBL054W"
/gene_synonym="PBF1"
/note="PAC motif binding protein involved in rRNA and
ribosome biogenesis; subunit of the RPD3L histone
deacetylase complex; Myb-like HTH transcription factor;
hypophosphorylated by rapamycin treatment in a
Sch9p-dependent manner; TOD6 has a paralog, DOT6, that
arose from the whole genome duplication"
/codon_start=1
/product="Tod6p"
/protein_id="NP_009499.1"
/db_xref="GI:6319417"
/db_xref="SGD:S000000150"
/db_xref="GeneID:852226"
/translation="MTLPKLSSVSVSSGHVSANSHGFSILSKHPHPNNLVHSHSLSHT
NAKSHLPISSTSTKENSTNKEEAESLKKNNPSSWDPSDDIKLRHLKEIKNLGWKEIAH
HFPNRTPNACQFRWRRLKSGNLKSNKTAVIDINKLFGVYATGDATPSAGTPSAEEAVK
EEAVEDEDITAGSSAIEDSPPDFKPLVKPKYMDRKLITQRSTSTFSDHEPQHTKPRKL
FVKPRSFSHSITTNTPNVKTAQQTNLSLYNTTSAKTNKAVNSNDYENIGLVPKIIIRS
RRNSFIPSTQIPHSTTKTRKNSHSVISSRRSSFNMMHSRRSSFNSHAPTEPISRRASL
VVSPYMSPRRLSTSQSVHYHPQHQYYLNPIASPNCKTDHANDKITHTRTFLDMQKFAN
KHPWSREDDEVLLNNTKDKQNHLSPLEISIVLPNNRSELEIQQRMDYLKRKGRVSGFH
TNEGCKDEEEEDDIDPLHKENGINTPSQQSQNYGMLEAKHDNPKSSELSSMTSANDIR
NEQDELPGINSIFKNIF"
gene complement(119379..121874)
/gene="SAS3"
/locus_tag="YBL052C"
/db_xref="GeneID:852228"
mRNA complement(119379..121874)
/gene="SAS3"
/locus_tag="YBL052C"
/product="Sas3p"
/transcript_id="NM_001178292.1"
/db_xref="GI:296142615"
/db_xref="GeneID:852228"
CDS complement(119379..121874)
/gene="SAS3"
/locus_tag="YBL052C"
/EC_number="2.3.1.48"
/note="Histone acetyltransferase catalytic subunit of NuA3
complex that acetylates histone H3, involved in
transcriptional silencing; homolog of the mammalian MOZ
proto-oncogene; mutant has aneuploidy tolerance; sas3gcn5
double mutation is lethal"
/codon_start=1
/product="Sas3p"
/protein_id="NP_009501.1"
/db_xref="GI:6319419"
/db_xref="SGD:S000000148"
/db_xref="GeneID:852228"
/translation="MSLTANDESPKPKKNALLKNLEIDDLIHSQFVRSDTNGHRTTRR
LFNSDASISHRIRGSVRSDKGLNKIKKGLISQQSKLASENSSQNIVNRDNKMGAVSFP
IIEPNIEVSEELKVRIKYDSIKFFNFERLISKSSVIAPLVNKNITSSGPLIGFQRRVN
RLKQTWDLATENMEYPYSSDNTPFRDNDSWQWYVPYGGTIKKMKDFSTKRTLPTWEDK
IKFLTFLENSKSATYINGNVSLCNHNETDQENEDRKKRKGKVPRIKNKVWFSQIEYIV
LRNYEIKPWYTSPFPEHINQNKMVFICEFCLKYMTSRYTFYRHQLKCLTFKPPGNEIY
RDGKLSVWEIDGRENVLYCQNLCLLAKCFINSKTLYYDVEPFIFYILTEREDTENHPY
QNAAKFHFVGYFSKEKFNSNDYNLSCILTLPIYQRKGYGQFLMEFSYLLSRKESKFGT
PEKPLSDLGLLTYRTFWKIKCAEVLLKLRDSARRRSNNKNEDTFQQVSLNDIAKLTGM
IPTDVVFGLEQLQVLYRHKTRSLSSLDDFNYIIKIDSWNRIENIYKTWSSKNYPRVKY
DKLLWEPIILGPSFGINGMMNLEPTALADEALTNETMAPVISNNTHIENYNNSRAHNK
RRRRRRRSSEHKTSKLHVNNIIEPEVPATDFFEDTVSSLTEYMCDYKNTNNDRLIYQA
EKRVLESIHDRKGIPRSKFSTETHWELCFTIKNSETPLGNHAARRNDTGISSLEQDEV
ENDVDTELYVGENAKEDEDEDEDFTLDDDIEDEQISEENDEEEDTYEEDSDDDEDGKR
KGQEQDENDIESHIRKERVRKRRKITLIEDDEE"
STS 119742..119940
/standard_name="px-31d10"
/db_xref="UniSTS:258372"
gene complement(122753..124759)
/gene="PIN4"
/locus_tag="YBL051C"
/gene_synonym="MDT1"
/db_xref="GeneID:852229"
mRNA complement(122753..124759)
/gene="PIN4"
/locus_tag="YBL051C"
/gene_synonym="MDT1"
/product="Pin4p"
/transcript_id="NM_001178291.1"
/db_xref="GI:296142616"
/db_xref="GeneID:852229"
CDS complement(122753..124759)
/gene="PIN4"
/locus_tag="YBL051C"
/gene_synonym="MDT1"
/note="Protein involved in G2/M phase progression and
response to DNA damage, interacts with Rad53p; contains an
RNA recognition motif, a nuclear localization signal, and
several SQ/TQ cluster domains; hyperphosphorylated in
response to DNA damage"
/codon_start=1
/product="Pin4p"
/protein_id="NP_009502.1"
/db_xref="GI:6319420"
/db_xref="SGD:S000000147"
/db_xref="GeneID:852229"
/translation="METSSFENAPPAAINDAQDNNINTETNDQETNQQSIETRDAIDK
ENGVQTETGENSAKNAEQNVSSTNLNNAPTNGALDDDVIPNAIVIKNIPFAIKKEQLL
DIIEEMDLPLPYAFNYHFDNGIFRGLAFANFTTPEETTQVITSLNGKEISGRKLKVEY
KKMLPQAERERIEREKREKRGQLEEQHRSSSNLSLDSLSKMSGSGNNNTSNNQLFSTL
MNGINANSMMNSPMNNTINNNSSNNNNSGNIILNQPSLSAQHTSSSLYQTNVNNQAQM
STERFYAPLPSTSTLPLPPQQLDFNDPDTLEIYSQLLLFKDREKYYYELAYPMGISAS
HKRIINVLCSYLGLVEVYDPRFIIIRRKILDHANLQSHLQQQGQMTSAHPLQPNSTGG
SMNRSQSYTSLLQAHAAAAANSISNQAVNNSSNSNTINSNNGNGNNVIINNNSASSTP
KISSQGQFSMQPTLTSPKMNIHHSSQYNSADQPQQPQPQTQQNVQSAAQQQQSFLRQQ
ATLTPSSRIPSGYSANHYQINSVNPLLRNSQISPPNSQIPINSQTLSQAQPPAQSQTQ
QRVPVAYQNASLSSQQLYNLNGPSSANSQSQLLPQHTNGSVHSNFSYQSYHDESMLSA
HNLNSADLIYKSLSHSGLDDGLEQGLNRSLSGLDLQNQNKKNLW"
gene 125125..126119
/gene="SEC17"
/locus_tag="YBL050W"
/gene_synonym="RNS3"
/db_xref="GeneID:852230"
mRNA join(125125..125154,125271..126119)
/gene="SEC17"
/locus_tag="YBL050W"
/gene_synonym="RNS3"
/product="Sec17p"
/transcript_id="NM_001178290.1"
/db_xref="GI:296142617"
/db_xref="GeneID:852230"
CDS join(125125..125154,125271..126119)
/gene="SEC17"
/locus_tag="YBL050W"
/gene_synonym="RNS3"
/note="Peripheral membrane protein required for vesicular
transport between ER and Golgi, the 'priming' step in
homotypic vacuole fusion, and autophagy; stimulates the
ATPase activity of Sec18p; has similarity to mammalian
alpha-SNAP"
/codon_start=1
/product="Sec17p"
/protein_id="NP_009503.1"
/db_xref="GI:6319421"
/db_xref="SGD:S000000146"
/db_xref="GeneID:852230"
/translation="MSDPVELLKRAEKKGVPSSGFMKLFSGSDSYKFEEAADLCVQAA
TIYRLRKELNLAGDSFLKAADYQKKAGNEDEAGNTYVEAYKCFKSGGNSVNAVDSLEN
AIQIFTHRGQFRRGANFKFELGEILENDLHDYAKAIDCYELAGEWYAQDQSVALSNKC
FIKCADLKALDGQYIEASDIYSKLIKSSMGNRLSQWSLKDYFLKKGLCQLAATDAVAA
ARTLQEGQSEDPNFADSRESNFLKSLIDAVNEGDSEQLSEHCKEFDNFMRLDKWKITI
LNKIKESIQQQEDDLL"
gene 126828..127244
/gene="MOH1"
/locus_tag="YBL049W"
/db_xref="GeneID:852231"
mRNA 126828..127244
/gene="MOH1"
/locus_tag="YBL049W"
/product="Moh1p"
/transcript_id="NM_001178289.1"
/db_xref="GI:296142618"
/db_xref="GeneID:852231"
CDS 126828..127244
/gene="MOH1"
/locus_tag="YBL049W"
/note="hypothetical protein, has homology to kinase Snf7p;
not required for growth on nonfermentable carbon sources;
essential for survival in stationary phase"
/codon_start=1
/product="Moh1p"
/protein_id="NP_009504.1"
/db_xref="GI:6319422"
/db_xref="SGD:S000000145"
/db_xref="GeneID:852231"
/translation="MGLRYSIYIENPLSSPSSSYKSINDPLFHSQHRSQKNVSFITYG
CRHCKTHLSSSFQIISRDYRGRTGTAYLMNKVVNVVEGKVEQRRMLTGDYLVCDILCH
WCKRNVGWKYLQSSNDDQQYKEGKFILELKNICKCT"
gene complement(127895..132040)
/gene="EDE1"
/locus_tag="YBL047C"
/gene_synonym="BUD15"
/db_xref="GeneID:852233"
mRNA complement(127895..132040)
/gene="EDE1"
/locus_tag="YBL047C"
/gene_synonym="BUD15"
/product="Ede1p"
/transcript_id="NM_001178287.1"
/db_xref="GI:296142619"
/db_xref="GeneID:852233"
CDS complement(127895..132040)
/gene="EDE1"
/locus_tag="YBL047C"
/gene_synonym="BUD15"
/note="Endocytic protein; involved in a network of
interactions with other endocytic proteins, binds
membranes in a ubiquitin-dependent manner, may also bind
ubiquitinated membrane-associated proteins; interacts with
Cmk2 and functions upstream of CMK2 in regulating
non-apoptotic cell death"
/codon_start=1
/product="Ede1p"
/protein_id="NP_009506.1"
/db_xref="GI:6319424"
/db_xref="SGD:S000000143"
/db_xref="GeneID:852233"
/translation="MASITFRTPLSSQEQAFYNQKFHQLDTEDLGVVTGEAVRPLFAS
SGLPGQLLSQVWATVDIDNKGFLNLNEFSAALRMIAQLQNAPNQPISAALYESTPTQL
ASFSINQNPAPMQSGSATGNTNNTDIPALSSNDIAKFSQLFDRTAKGAQTVAGDKAKD
IFLKARLPNQTLGEIWALCDRDASGVLDKSEFIMAMYLIQLCMSHHPSMNTPPAVLPT
QLWDSIRLEPVVVNQPNRTTPLSANSTGVSSLTRHSTISRLSTGAFSNAASDWSLSFE
KKQQFDAIFDSLDKQHAGSLSSAVLVPFFLSSRLNQETLATIWDLADIHNNAEFTKLE
FAIAMFLIQKKNAGVELPDVIPNELLQSPALGLYPPNPLPQQQSAPQIAIPSRASKPS
LQDMPHQVSAPAVNTQPTVPQVLPQNSNNGSLNDLLALNPSFSSPSPTKAQTVVQNNT
NNSFSYDNNNGQATLQQQQPQQPPPLTHSSSGLKKFTPTSNFGQSIIKEEPEEQEQLR
ESSDTFSAQPPPVPKHASSPVKRTASTTLPQVPNFSVFSMPAGAATSAATGAAVGAAV
GAAALGASAFSRSSNNAFKNQDLFADGEASAQLSNATTEMANLSNQVNSLSKQASITN
DKKSRATQELKRVTEMKNSIQIKLNNLRSTHDQNVKQTEQLEAQVLQVNKENETLAQQ
LAVSEANYHAAESKLNELTTDLQESQTKNAELKEQITNLNSMTASLQSQLNEKQQQVK
QERSMVDVNSKQLELNQVTVANLQKEIDGLGEKISVYLTKQKELNDYQKTVEEQHAQL
QAKYQDLSNKDTDLTDREKQLEERNRQIEEQENLYHQHVSKLQEMFDDLSQRKASFEK
ADQELKERNIEYANNVRELSERQMNLAMGQLPEDAKDIIAKSASNTDTTTKEATSRGN
VHEDTVSKFVETTVENSNLNVNRVKDDEEKTERTESDVFDRDVPTLGSQSDSENANTN
NGTQSGNETANPNLTETLSDRFDGDLNEYGIPRSQSLTSSVANNAPQSVRDDVELPET
LEERDTINNTANRDNTGNLSHIPGEWEATPATASTDVLSNETTEVIEDGSTTKRANSN
EDGESVSSIQESPKISAQPKAKTINEEFPPIQELHIDESDSSSSDDDEFEDTREIPSA
TVKTLQTPYNAQPTSSLEIHTEQVIKYPAPGTSPSHNEGNSKKASTNSILPVKDEFDD
EFAGLEQAAVEEDNGADSESEFENVANAGSMEQFETIDHKDLDDELQMNAFTGTLTSS
SNPTIPKPQVQQQSTSDPAQVSNDEWDEIFAGFGNSKAEPTKVATPSIPQQPIPLKND
PIVDASLSKGPIVNRGVATTPKSLAVEELSGMGFTEEEAHNALEKCNWDLEAATNFLL
DSA"
gene 132424..133749
/gene="PSY4"
/locus_tag="YBL046W"
/db_xref="GeneID:852234"
mRNA 132424..133749
/gene="PSY4"
/locus_tag="YBL046W"
/product="Psy4p"
/transcript_id="NM_001178286.1"
/db_xref="GI:296142620"
/db_xref="GeneID:852234"
CDS 132424..133749
/gene="PSY4"
/locus_tag="YBL046W"
/note="Regulatory subunit of protein phosphatase PP4;
presence of Psy4p in the PP4 complex (along with catalytic
subunit Pph3p and Psy2p) is required for dephosphorylation
of the histone variant H2AX, but not for dephosphorylation
of Rad53p, during recovery from the DNA damage checkpoint;
localization is cell-cycle dependent and regulated by
Cdc28p phosphorylation; required for cisplatin resistance;
homolog of mammalian R2"
/codon_start=1
/product="Psy4p"
/protein_id="NP_009507.1"
/db_xref="GI:6319425"
/db_xref="SGD:S000000142"
/db_xref="GeneID:852234"
/translation="MSSTMLDDVDNNMMGIKSISLYELLSDVVKQGDKTRLVTAGPEQ
VLPDLIRHITETIPFDLFINLKNEMNDARNLVTRLNWLGKFLNDNFLQNHTFPFTILR
ICELCYDPFKYYKINELEKFVNALEKCCMVTSSWQVFDKTHGEKQEDDKEKDINFIKN
QEDVSLMKIPWMTENNTRELAPFIREIDSIMSVNLGYDDEDEEEGFFDGDEDREMGNK
SKRNVLLKDENFMVEEYYEDDCGINDDNSDNKGQNCQSDVTKNNSDDEDDDDNDDDYR
EDGADEDDEDDDHMGSTDDDEDDDEDRQAGESTKVQNFDKKNETPRKRKPTDLDNFEY
DESPSFTNMDLTTPKKYKHTATGRFSIIESPSSSLLNAMDGSNEISSSQEEEKEDAHE
NHEGRSEGLLPGDELVSPSMSSSQEDKMVAIAGITYRENISSPLGKKSR"
gene complement(134143..135516)
/gene="COR1"
/locus_tag="YBL045C"
/gene_synonym="QCR1"
/db_xref="GeneID:852235"
mRNA complement(134143..135516)
/gene="COR1"
/locus_tag="YBL045C"
/gene_synonym="QCR1"
/product="ubiquinol--cytochrome-c reductase subunit COR1"
/transcript_id="NM_001178285.1"
/db_xref="GI:296142621"
/db_xref="GeneID:852235"
CDS complement(134143..135516)
/gene="COR1"
/locus_tag="YBL045C"
/gene_synonym="QCR1"
/note="Core subunit of the ubiquinol-cytochrome c
reductase complex (bc1 complex), which is a component of
the mitochondrial inner membrane electron transport chain"
/codon_start=1
/product="ubiquinol--cytochrome-c reductase subunit COR1"
/protein_id="NP_009508.1"
/db_xref="GI:6319426"
/db_xref="SGD:S000000141"
/db_xref="GeneID:852235"
/translation="MLRTVTSKTVSNQFKRSLATAVATPKAEVTQLSNGIVVATEHNP
SAHTASVGVVFGSGAANENPYNNGVSNLWKNIFLSKENSAVAAKEGLALSSNISRDFQ
SYIVSSLPGSTDKSLDFLNQSFIQQKANLLSSSNFEATKKSVLKQVQDFEENDHPNRV
LEHLHSTAFQNTPLSLPTRGTLESLENLVVADLESFANNHFLNSNAVVVGTGNIKHED
LVNSIESKNLSLQTGTKPVLKKKAAFLGSEVRLRDDTLPKAWISLAVEGEPVNSPNYF
VAKLAAQIFGSYNAFEPASRLQGIKLLDNIQEYQLCDNFNHFSLSYKDSGLWGFSTAT
RNVTMIDDLIHFTLKQWNRLTISVTDTEVERAKSLLKLQLGQLYESGNPVNDANLLGA
EVLIKGSKLSLGEAFKKIDAITVKDVKAWAGKRLWDQDIAIAGTGQIEGLLDYMRIRS
DMSMMRW"
gene 135998..136366
/locus_tag="YBL044W"
/db_xref="GeneID:852236"
mRNA 135998..136366
/locus_tag="YBL044W"
/product="hypothetical protein"
/transcript_id="NM_001178284.1"
/db_xref="GI:296142622"
/db_xref="GeneID:852236"
CDS 135998..136366
/locus_tag="YBL044W"
/note="hypothetical protein; YBL044W is not an essential
protein"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009509.1"
/db_xref="GI:6319427"
/db_xref="SGD:S000000140"
/db_xref="GeneID:852236"
/translation="MGEMLERQKKRLPSKAKYLKYTASITETGNHEADSSVIFRPHHS
DVTCSNARRAESRTLPQICSCILLDHGRRTRPEVRTGMVSLHGSFKGFPCFGIRRGIS
HVLPGQKLRGSCDNWKKRQN"
gene 136688..137461
/gene="ECM13"
/locus_tag="YBL043W"
/db_xref="GeneID:852237"
mRNA 136688..137461
/gene="ECM13"
/locus_tag="YBL043W"
/product="Ecm13p"
/transcript_id="NM_001178283.1"
/db_xref="GI:296142623"
/db_xref="GeneID:852237"
CDS 136688..137461
/gene="ECM13"
/locus_tag="YBL043W"
/note="Non-essential hypothetical protein; induced by
treatment with 8-methoxypsoralen and UVA irradiation;
ECM13 has a paralog, YJR115W, that arose from the whole
genome duplication"
/codon_start=1
/product="Ecm13p"
/protein_id="NP_009510.1"
/db_xref="GI:6319428"
/db_xref="SGD:S000000139"
/db_xref="GeneID:852237"
/translation="MNSTTPSIQDQYILASKVRSKLAKCVSVTTKNKDYNLRVLVGHA
NLLDKITENVETHNAATNALAGDPFSKGPENLSIEHIELSNANASKNDVGKEENAEKT
IESEDYCDFYSSDEDPDADTLSSTDSEDDDDYEDYDFEYDYSGGDYNKKIDMYFSFHT
APNYQYLTHTNSHSEQTDELAESTPRYNALPATASTTEEEQDTETLDAVSLHSSAPIF
RVLSRRVNGQEDDSENESSSDVDDGSVPLTRFHSCPITA"
gene complement(138341..140260)
/gene="FUI1"
/locus_tag="YBL042C"
/db_xref="GeneID:852238"
mRNA complement(138341..140260)
/gene="FUI1"
/locus_tag="YBL042C"
/product="Fui1p"
/transcript_id="NM_001178282.1"
/db_xref="GI:296142624"
/db_xref="GeneID:852238"
CDS complement(138341..140260)
/gene="FUI1"
/locus_tag="YBL042C"
/note="High affinity uridine permease, localizes to the
plasma membrane; also mediates low but significant
transport of the cytotoxic nucleoside analog
5-fluorouridine; not involved in uracil transport;
relative distribution to the vacuole increases upon DNA
replication stress"
/codon_start=1
/product="Fui1p"
/protein_id="NP_009511.1"
/db_xref="GI:6319429"
/db_xref="SGD:S000000138"
/db_xref="GeneID:852238"
/translation="MPVSDSGFDNSSKTMKDDTIPTEDYEEITKESEMGDATKITSKI
DANVIEKKDTDSENNITIAQDDEKVSWLQRVVEFFEVKNDSTDLADHKPENPIRTFKD
LQESLRSTYLYNTDLRPVEAKRRTWTWKQYIFFWISGSFNVNTWQISATGLQLGLNWW
QTWICIWVGYTFVAFFLILGSKVGNNYHISFPISSRVSFGIYFSIWIVINRVVMACVW
NSTLAYIGSQCVQLMLKAIFGTNLNTRIKDTIKNPNLTNFEFMCFMVFWVACLPFLWF
PPDKLRHIFALKSAITPFAAFGFLIWTLCKAKGHLALGSLNDNGGAISKTVLAWSVIR
AIMSALDNFSTLILNAPDFTRFGKTYKSSVYSQLIALPVCYAIISLIGILSVSAAYTL
YGVNYWSPLDILNRYLDNYTSGNRAGVFLISFIFAFDQLGANLSGNSIPAGTDLTALL
PKFINIRRGSYICALISLAICPWDLLSSSSKFTTALAAYAVFLSAIAGVISADYFIVR
KGYVNIFHCYTDKPGSYYMYNKYGTNWRAVVAYIFGIAPNFAGFLGSVGVSVPIGAMK
VYYLNYFVGYLLAALSYCILVYFYPIKGIPGDAKITDRKWLEEWVEVEEFGTEREAFE
EYGGVSTGYEKIRYI"
gene 141247..141972
/gene="PRE7"
/locus_tag="YBL041W"
/gene_synonym="PRS3"
/db_xref="GeneID:852239"
mRNA 141247..141972
/gene="PRE7"
/locus_tag="YBL041W"
/gene_synonym="PRS3"
/product="proteasome core particle subunit beta 6"
/transcript_id="NM_001178281.1"
/db_xref="GI:296142625"
/db_xref="GeneID:852239"
CDS 141247..141972
/gene="PRE7"
/locus_tag="YBL041W"
/gene_synonym="PRS3"
/EC_number="3.4.25.1"
/note="Beta 6 subunit of the 20S proteasome"
/codon_start=1
/product="proteasome core particle subunit beta 6"
/protein_id="NP_009512.1"
/db_xref="GI:6319430"
/db_xref="SGD:S000000137"
/db_xref="GeneID:852239"
/translation="MATIASEYSSEASNTPIEHQFNPYGDNGGTILGIAGEDFAVLAG
DTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKK
LSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGA
AASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVG
DGLEILIVTKDGVRKEFYELKRD"
gene complement(142112..142868)
/gene="ERD2"
/locus_tag="YBL040C"
/db_xref="GeneID:852240"
mRNA complement(join(142112..142749,142847..142868))
/gene="ERD2"
/locus_tag="YBL040C"
/product="Erd2p"
/transcript_id="NM_001178280.1"
/db_xref="GI:296142626"
/db_xref="GeneID:852240"
CDS complement(join(142112..142749,142847..142868))
/gene="ERD2"
/locus_tag="YBL040C"
/note="HDEL receptor, an integral membrane protein that
binds to the HDEL motif in proteins destined for retention
in the endoplasmic reticulum; has a role in maintenance of
normal levels of ER-resident proteins"
/codon_start=1
/product="Erd2p"
/protein_id="NP_009513.1"
/db_xref="GI:6319431"
/db_xref="SGD:S000000136"
/db_xref="GeneID:852240"
/translation="MNPFRILGDLSHLTSILILIHNIKTTRYIEGISFKTQTLYALVF
ITRYLDLLTFHWVSLYNALMKIFFIVSTAYIVVLLQGSKRTNTIAYNEMLMHDTFKIQ
HLLIGSALMSVFFHHKFTFLELAWSFSVWLESVAILPQLYMLSKGGKTRSLTVHYIFA
MGLYRALYIPNWIWRYSTEDKKLDKIAFFAGLLQTLLYSDFFYIYYTKVIRGKGFKLP
K"
gene 143393..143572
/locus_tag="YBL039W-B"
/gene_synonym="YBL039W-A"
/db_xref="GeneID:1466441"
mRNA 143393..143572
/locus_tag="YBL039W-B"
/gene_synonym="YBL039W-A"
/product="hypothetical protein"
/transcript_id="NM_001184527.1"
/db_xref="GI:296142627"
/db_xref="GeneID:1466441"
CDS 143393..143572
/locus_tag="YBL039W-B"
/gene_synonym="YBL039W-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878045.1"
/db_xref="GI:33438763"
/db_xref="SGD:S000028517"
/db_xref="GeneID:1466441"
/translation="MGFFNNNPVIEFFHRITRKPSTIAMWVFAGLICSSTFYLMFMSS
PTIDFNSKSKKKNDK"
gene complement(143989..145728)
/gene="URA7"
/locus_tag="YBL039C"
/db_xref="GeneID:852241"
mRNA complement(143989..145728)
/gene="URA7"
/locus_tag="YBL039C"
/product="CTP synthase URA7"
/transcript_id="NM_001178279.1"
/db_xref="GI:296142628"
/db_xref="GeneID:852241"
CDS complement(143989..145728)
/gene="URA7"
/locus_tag="YBL039C"
/EC_number="6.3.4.2"
/note="Major CTP synthase isozyme (see also URA8);
catalyzes the ATP-dependent transfer of the amide nitrogen
from glutamine to UTP, forming CTP, the final step in de
novo biosynthesis of pyrimidines; involved in phospholipid
biosynthesis; URA7 has a paralog, URA8, that arose from
the whole genome duplication"
/codon_start=1
/product="CTP synthase URA7"
/protein_id="NP_009514.1"
/db_xref="GI:6319432"
/db_xref="SGD:S000000135"
/db_xref="GeneID:852241"
/translation="MKYVVVSGGVISGIGKGVLASSTGMLMKTLGLKVTSIKIDPYMN
IDAGTMSPLEHGECFVLDDGGETDLDLGNYERYLGVTLTKDHNITTGKIYSHVIAKER
KGDYLGKTVQIVPHLTNAIQDWIERVAKIPVDDTGMEPDVCIIELGGTVGDIESAPFV
EALRQFQFKVGKENFALIHVSLVPVIHGEQKTKPTQAAIKGLRSLGLVPDMIACRCSE
TLDKPTIDKIAMFCHVGPEQVVNVHDVNSTYHVPLLLLEQKMIDYLHARLKLDEISLT
EEEKQRGLELLSKWKATTGNFDESMETVKIALVGKYTNLKDSYLSVIKALEHSSMKCR
RKLDIKWVEATDLEPEAQESNKTKFHEAWNMVSTADGILIPGGFGVRGTEGMVLAARW
ARENHIPFLGVCLGLQIATIEFTRSVLGRKDSHSAEFYPDIDEKNHVVVFMPEIDKET
MGGSMRLGLRPTFFQNETEWSQIKKLYGDVSEVHERHRHRYEINPKMVDELENNGLIF
VGKDDTGKRCEILELKNHPYYIATQYHPEYTSKVLDPSKPFLGLVAASAGILQDVIEG
KYDLEAGENKFNF"
gene 146187..146885
/gene="MRPL16"
/locus_tag="YBL038W"
/db_xref="GeneID:852242"
mRNA 146187..146885
/gene="MRPL16"
/locus_tag="YBL038W"
/product="mitochondrial 54S ribosomal protein YmL47"
/transcript_id="NM_001178278.1"
/db_xref="GI:296142629"
/db_xref="GeneID:852242"
CDS 146187..146885
/gene="MRPL16"
/locus_tag="YBL038W"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL47"
/protein_id="NP_009515.1"
/db_xref="GI:6319433"
/db_xref="SGD:S000000134"
/db_xref="GeneID:852242"
/translation="MFPYLTRMNLSIKMGGLTLKESSPNAFLNNTTIARRFKHEYAPR
FKIVQKKQKGRVPVRTGGSIKGSTLQFGKYGLRLKSEGIRISAQQLKEADNAIMRYVR
PLNNGHLWRRLCTNVAVCIKGNETRMGKGKGGFDHWMVRVPTGKILFEINGDDLHEKV
AREAFRKAGTKLPGVYEFVSLDSLVRVGLHSFKNPKDDPVKNFYDENAKKPSKKYLNI
LKSQEPQYKLFRGR"
gene 147209..150286
/gene="APL3"
/locus_tag="YBL037W"
/db_xref="GeneID:852243"
mRNA 147209..150286
/gene="APL3"
/locus_tag="YBL037W"
/product="Apl3p"
/transcript_id="NM_001178277.1"
/db_xref="GI:296142630"
/db_xref="GeneID:852243"
CDS 147209..150286
/gene="APL3"
/locus_tag="YBL037W"
/note="Alpha-adaptin, large subunit of the clathrin
associated protein complex (AP-2); involved in vesicle
mediated transport"
/codon_start=1
/product="Apl3p"
/protein_id="NP_009516.1"
/db_xref="GI:6319434"
/db_xref="SGD:S000000133"
/db_xref="GeneID:852243"
/translation="MDRKKTLINSSVSNNNSTIKGLQLFIADLRSAQQAQEQEKRIQS
EIVKIKQHFDAAKKKQGNHDRLGGYQRKKYVAKLAYIYITSNTTKLNEILFGLEQTVE
LLKSSIFSEKFIGYMTLELLYERSEVVAKVNDEVNYQLMKDLSSSDDNFVMLALNFVG
VVGELTNRLAYNDDITTGVFKILRSPTSSIYLKKKSALSFLALLKSNHSILTEDLQRK
QLWIQRILSLLDDTENYRLTLATIPLIEFIAKYIDPSYCTRLLPQLTEILYNCVVVGT
SRSSDNQFPLEYTFANMPNPWLITKVVSLLSILIASPTERDSGSLLQTNNIDNELLNK
LRKCVSVAIELGTRQAQDPMERIVQNTVLFSLINFASKLDPSDEAISNSVTALCSLLT
SKEINIRYLTLDSLVKLCSSSGKPAIDAVRYKNLDMIFHLLNTERDSSIVRKVVDLLY
TFTDVENVKIIVDGLLQYILSPKNLAEPQIKSDIAVKIAILTEKYATDINWFVIISLQ
LLSLTSNTTINDDEIWQRLCQIVVNNPSLHRITCERLVDYLCKKQASEAIIKAAAFLL
GEYSSLITDRISSANLFTLFAEKYFSAPNVAKAMILTTMIKLYKTSPEIGSNVIKFFQ
LELNSLDIELQTRSFEYLNIIQLAKVNGNTDILQILFEPMPPFNSKSNPLLKRLGSLP
ASAGSTTLINTPSEASSSTPDLLSKRANSSRSIMVPMPPPSRRNTIDDVNSKISSSED
FSGKDSYYSRQILAPNWREGFTRMISHKQGVLFTSSLMKVFYRITTPDAQQPYVFHIS
LAFINLTEWEITGLSTQIIPSKTQGNPEYLIMNINTPSTATIGPHKRAEQSYEVSIRK
PFDVEDSPILAIHFKCGGSTNTINLKTAIGMTTTLISSDVNPSMHLNLAQFISRWKTL
SDALGKEGEYQKSGIKLNKDFRKVETISLEDGLLLLTQTVKRLGFDIVDQTSVRSTLF
VSGIIHTKSEGNFGCLMKIQYQVNGTVNVTCKTTTAGPLAKYIVECIKNVLTK"
gene complement(150447..151220)
/locus_tag="YBL036C"
/db_xref="GeneID:852244"
mRNA complement(150447..151220)
/locus_tag="YBL036C"
/product="hypothetical protein"
/transcript_id="NM_001178276.1"
/db_xref="GI:296142631"
/db_xref="GeneID:852244"
CDS complement(150447..151220)
/locus_tag="YBL036C"
/note="Putative non-specific single-domain racemase based
on structural similarity; binds pyridoxal 5'-phosphate;
expression of GFP-fusion protein induced in response to
the DNA-damaging agent MMS"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009517.1"
/db_xref="GI:6319435"
/db_xref="SGD:S000000132"
/db_xref="GeneID:852244"
/translation="MSTGITYDEDRKTQLIAQYESVREVVNAEAKNVHVNENASKILL
LVVSKLKPASDIQILYDHGVREFGENYVQELIEKAKLLPDDIKWHFIGGLQTNKCKDL
AKVPNLYSVETIDSLKKAKKLNESRAKFQPDCNPILCNVQINTSHEDQKSGLNNEAEI
FEVIDFFLSEECKYIKLNGLMTIGSWNVSHEDSKENRDFATLVEWKKKIDAKFGTSLK
LSMGMSADFREAIRQGTAEVRIGTDIFGARPPKNEARII"
gene complement(151493..153610)
/gene="POL12"
/locus_tag="YBL035C"
/db_xref="GeneID:852245"
mRNA complement(151493..153610)
/gene="POL12"
/locus_tag="YBL035C"
/product="Pol12p"
/transcript_id="NM_001178275.1"
/db_xref="GI:296142632"
/db_xref="GeneID:852245"
CDS complement(151493..153610)
/gene="POL12"
/locus_tag="YBL035C"
/note="B subunit of DNA polymerase alpha-primase complex,
required for initiation of DNA replication during mitotic
and premeiotic DNA synthesis; also functions in telomere
capping and length regulation"
/codon_start=1
/product="Pol12p"
/protein_id="NP_009518.1"
/db_xref="GI:6319436"
/db_xref="SGD:S000000131"
/db_xref="GeneID:852245"
/translation="MSGSIDVITHFGPDADKPEIITALENLTKLHALSVEDLYIKWEQ
FSNQRRQTHTDLTSKNIDEFKQFLQLQMEKRANQISSSSKVNTSTKKPVIKKSLNSSP
LFGLSIPKTPTLKKRKLHGPFSLSDSKQTYNVGSEAETNEKGNSSLKLEFTPGMAEDA
VGDSAPLSHAKSSDAKTPGSSTFQTPTTNTPTTSRQNVPAGEILDSLNPENIEISSGN
PNVGLLSTEEPSYNQVKVEPFYDAKKYKFRTMRQNLQEASDVLDDQIESFTKIIQNHY
KLSPNDFADPTIQSQSEIYAVGRIVPDSPTYDKFLNPESLSLETSRMGGVGRRVRLDL
SQVNELSFFLGQIVAFKGKNANGDYFTVNSILPLPYPNSPVSTSQELQEFQANLEGSS
LKVIVTCGPYFANDNFSLELLQEFIDSINNEVKPHVLIMFGPFIDITHPLIASGKLPN
FPQFKTQPKTLDELFLKLFTPILKTISPHIQTVLIPSTKDAISNHAAYPQASLIRKAL
QLPKRNFKCMANPSSFQINEIYFGCSNVDTFKDLKEVIKGGTTSSRYRLDRVSEHILQ
QRRYYPIFPGSIRTRIKPKDVSTKKETNDMESKEEKVYEHISGADLDVSYLGLTEFVG
GFSPDIMIIPSELQHFARVVQNVVVINPGRFIRATGNRGSYAQITVQCPDLEDGKLTL
VEGEEPVYLHNVWKRARVDLIAS"
gene complement(153848..158389)
/gene="STU1"
/locus_tag="YBL034C"
/db_xref="GeneID:852246"
mRNA complement(153848..158389)
/gene="STU1"
/locus_tag="YBL034C"
/product="Stu1p"
/transcript_id="NM_001178274.1"
/db_xref="GI:296142633"
/db_xref="GeneID:852246"
CDS complement(153848..158389)
/gene="STU1"
/locus_tag="YBL034C"
/note="Component of the mitotic spindle that binds to
interpolar microtubules via its association with
beta-tubulin (Tub2p); required for interpolar microtubules
to provide an outward force on the spindle poles"
/codon_start=1
/product="Stu1p"
/protein_id="NP_009519.1"
/db_xref="GI:6319437"
/db_xref="SGD:S000000130"
/db_xref="GeneID:852246"
/translation="MSSFNNETNNNSNTNTHPDDSFPLYTVFKDESVPIEEKMALLTR
FKGHVKKELVNESSIQAYFAALLFISGHYAYRSYPRLIFLSHSSLCYLIKRVAMQSPV
QFNDTLVEQLLNHLIFELPNEKKFWLASIKAIEAIYLVNPSKIQAILANFLRRPSENQ
NGDYLNRIKSTLLTIDELIQINEKNNSNHLQLLRFFMLSFTNLLNNNLNEHANDDNNN
VIIELIFDIMYKYLKMDDENSQDLIDGFINDLEVEKFKQKFISLAKSQDQHGSQEDKS
TLFDEEYEFQLLLAEAKLPQLSNNLSSKDPAMKKNYESLNQLQQDLENLLAPFQSVKE
TEQNWKLRQSNIIELDNIISGNIPKDNPEEFVTVIKEVQLIELISRATSSLRTTLSLT
ALLFLKRLIHILNDQLPLSILDQIFVIFKNLLSSTKKISSQTAFHCLITLIIDINHFH
NKLFQLSFLLINEKTVTPRFCSAILLRSFLIKFNDSNLSLNNSNTTSPTSKLENNIIY
IEEWLKKGISDSQTTVREAMRLTFWYFYKCYPTNAKRLLSSSFSPQLKKATELAIPAH
LNINYQVSRVSSTASASSATSRLYSHSSNNSSRKTSLLEQKRNYPSYAQPTQSSSTSL
LNAPAVTAGGSVIASKLSNKLKTNLRSTSEYSSKENEKRARHHDSMNSVSNSNTKDNN
NVTKRKVSAPPSSTAATKVSENYTNFDDFPSNQIDLTDELSNSYSNPLIKKYMDKNDV
SMSSSPISLKGSNKLGEYETLYKKFNDASFPAQIKDALQYLQKELLLTSQQSSSAPKF
EFPMIMKKLRQIMIKSPNDFKPFLSIEKFTNGVPLNYLIELYSINSFDYAEILKNRMN
PEKPYELTNLIITIADLFNFLNANNCPNDFKLYYMKYKTTFFNYNFKLLLEIFRNLNI
KHDNTLRSGTNDLMPKISMILFQIYGKEFDYTCYFNLIFEIYKFDNNRFNKLLADFDI
VSTKMKICHELEKKDANFKVEDIISRESSVSFTPIDNKKSEGDEESDDAVDENDVKKC
MEMTMINPFKNLETDKTLELKNNVGKRTSSTDSVVIHDDNDKDKKLSEMTKIVSVYQL
DQPNPAKEEDDIDMENSQKSDLNLSEIFQNSGENTERKLKDDNEPTVKFSTDPPKIIN
EPEKLIGNGNENEKPDLETMSPIKINGDENMGQKQRITVKRERDVALTEQDINSKKMK
LVNNKKSEKMHLLIMDNFPRDSLTVYEISHLLMVDSNGNTLMDFDVYFNHMSKAINRI
KSGSFTMKHINYLIEPLITCFQNQKMTDWLTNENGFDELLDVAIMLLKSTDDTPSIPS
KISSKSIILVHCLLVWKKFLNTLSENADDDGVSVRMCFEEVWEQILLMLNKFSDYGNE
IYKLAQEFRDSLMLSHFFKKHSATRILSMLVTEIQPDTAGVKETFLIETLWKMLQSPT
ICQQFKKSNISEIIQTMSYFIMGTDNTSWNFTSAVVLARCLRVLQTTPDYTEQETERL
FDCLPKNVFKMIMFIASNE"
gene complement(158656..159693)
/gene="RIB1"
/locus_tag="YBL033C"
/db_xref="GeneID:852247"
mRNA complement(158656..159693)
/gene="RIB1"
/locus_tag="YBL033C"
/product="GTP cyclohydrolase II"
/transcript_id="NM_001178273.1"
/db_xref="GI:296142634"
/db_xref="GeneID:852247"
CDS complement(158656..159693)
/gene="RIB1"
/locus_tag="YBL033C"
/EC_number="3.5.4.25"
/note="GTP cyclohydrolase II; catalyzes the first step of
the riboflavin biosynthesis pathway"
/codon_start=1
/product="GTP cyclohydrolase II"
/protein_id="NP_009520.1"
/db_xref="GI:6319438"
/db_xref="SGD:S000000129"
/db_xref="GeneID:852247"
/translation="MTIDNYDNSKQDSSKYEVSGTGDGRNGDGGLPLVQCVARARIPT
TQGPDIFLHLYSNNRDNKEHLAIVFGEDIRSRSLFRRRQCETQQDRMIRGAYIGKLYP
GRTVADEDDRLGLALEFDDSTGELLASKATTWDAHNDTLVRIHSECYTGENAWSARCD
CGEQFDRAGRLIACDHEPTSNIKGGNGHGVIVYLRQEGRGIGLGEKLKAYNLQDLGAD
TVQANLMLKHPVDARDFSLGKAILLDLGIGNVRLLTNNPEKIKQVDHAPYLKCVERVP
MVPIHWTNSSEGIDSKEIEGYLRTKIERMGHLLTEPLKLHTNPQPTETSEAQNQNRMN
SALSSTSTLAI"
gene 160184..161329
/gene="HEK2"
/locus_tag="YBL032W"
/gene_synonym="KHD1"
/db_xref="GeneID:852248"
mRNA 160184..161329
/gene="HEK2"
/locus_tag="YBL032W"
/gene_synonym="KHD1"
/product="Hek2p"
/transcript_id="NM_001178272.1"
/db_xref="GI:296142635"
/db_xref="GeneID:852248"
CDS 160184..161329
/gene="HEK2"
/locus_tag="YBL032W"
/gene_synonym="KHD1"
/note="RNA binding protein involved in the asymmetric
localization of ASH1 mRNA; represses translation of ASH1
mRNA, an effect reversed by Yck1p-dependent
phosphoryation; regulates telomere position effect and
length; similarity to hnRNP-K"
/codon_start=1
/product="Hek2p"
/protein_id="NP_009521.1"
/db_xref="GI:6319439"
/db_xref="SGD:S000000128"
/db_xref="GeneID:852248"
/translation="MSQFFEAATPVAIPTNNTNGGSSDAGSAATGGAPVVGTTAQPTI
NHRLLLSLKEAAKIIGTKGSTISRIRAANAVKIGISEKVPGCSDRILSCAGNVINVAN
AIGDIVDVLNKRNPENEDAAEGEAEEHYYFHFLNHILPAPSKDEIRDLQQLEDIGYVR
LIVANSHISSIIGKAGATIKSLINKHGVKIVASKDFLPASDERIIEIQGFPGSITNVL
IEISEIILSDVDVRFSTERSYFPHLKKSSGEPTSPSTSSNTRIELKIPELYVGAIIGR
GMNRIKNLKTFTKTNIVVERKDDDDKDENFRKFIITSKFPKNVKLAESMLLKNLNTEI
EKRENYKRKLEAAEGDATVVTERSDSASFLEEKEEPQENHDNKEEQS"
gene 161699..162715
/gene="SHE1"
/locus_tag="YBL031W"
/db_xref="GeneID:852249"
mRNA 161699..162715
/gene="SHE1"
/locus_tag="YBL031W"
/product="She1p"
/transcript_id="NM_001178271.1"
/db_xref="GI:296142636"
/db_xref="GeneID:852249"
CDS 161699..162715
/gene="SHE1"
/locus_tag="YBL031W"
/note="Mitotic spindle protein; interacts with components
of the Dam1 (DASH) complex, its effector Sli15p, and
microtubule-associated protein Bim1p; also localizes to
nuclear microtubules and to the bud neck in a ring-shaped
structure; inhibits dynein function"
/codon_start=1
/product="She1p"
/protein_id="NP_009522.1"
/db_xref="GI:6319440"
/db_xref="SGD:S000000127"
/db_xref="GeneID:852249"
/translation="MNDKLQEEHNEKDTTSQINGFTPPHMSIDFHSNNNSNIIETIGV
SKRLGNSVLSELDSRASSKFEFLKDQSEQQYNGDKNNEPKSGSYNINEFFQAKHDSQF
GQMESLDTHYTLLHTPKRKSQHAIPQDRSDSMKRSRPSRSIPYTTPVVNDITRRIRRL
KLRNSLVNGNDIVARARSMQANSNINSIKNTPLSKPKPFMHKPNFLMPTTNSLNKINS
AHRNTSSSSTASSIPRSKVHRSISIRDLHAKTKPVERTPVAQGTNSQLKNSVSVFDRL
YKQTTFSRSTSMNNLSSGTSAKSKEHTNVKTRLVKSKTSGSLSSNLKQSTATGTKSDR
PIWR"
gene complement(163041..163997)
/gene="PET9"
/locus_tag="YBL030C"
/gene_synonym="AAC2; ANC2"
/db_xref="GeneID:852250"
mRNA complement(163041..163997)
/gene="PET9"
/locus_tag="YBL030C"
/gene_synonym="AAC2; ANC2"
/product="Pet9p"
/transcript_id="NM_001178270.1"
/db_xref="GI:296142637"
/db_xref="GeneID:852250"
CDS complement(163041..163997)
/gene="PET9"
/locus_tag="YBL030C"
/gene_synonym="AAC2; ANC2"
/note="Major ADP/ATP carrier of the mitochondrial inner
membrane; exchanges cytosolic ADP for mitochondrially
synthesized ATP; also imports heme and ATP;
phosphorylated; required for viability in many lab strains
that carry a sal1 mutation; PET9 has a paralog, AAC3, that
arose from the whole genome duplication"
/codon_start=1
/product="Pet9p"
/protein_id="NP_009523.1"
/db_xref="GI:6319441"
/db_xref="SGD:S000000126"
/db_xref="GeneID:852250"
/translation="MSSNAQVKTPLPPAPAPKKESNFLIDFLMGGVSAAVAKTAASPI
ERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQA
LNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADSK
SSKKGGARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLL
LTGSLEGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYDGAFDCLRKIV
AAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK"
gene complement(164488..164772)
/locus_tag="YBL029C-A"
/db_xref="GeneID:852251"
mRNA complement(164488..164772)
/locus_tag="YBL029C-A"
/product="hypothetical protein"
/transcript_id="NM_001184457.1"
/db_xref="GI:296142638"
/db_xref="GeneID:852251"
CDS complement(164488..164772)
/locus_tag="YBL029C-A"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cell periphery;
protein abundance increases in response to DNA replication
stress; has potential orthologs in Saccharomyces species
and in Yarrowia lipolytica"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_076874.1"
/db_xref="GI:13129152"
/db_xref="SGD:S000007591"
/db_xref="GeneID:852251"
/translation="MSFIPIVCGMKSFDSSYDTVPGHQNLYCPNCHNYSVGPIKRKEF
FTIWFIPLVPVFWGKQLHCPICNWRQDFKNDEQLNKVIQEQQNLRQKQPN"
gene 166134..167264
/locus_tag="YBL029W"
/db_xref="GeneID:852252"
mRNA 166134..167264
/locus_tag="YBL029W"
/product="hypothetical protein"
/transcript_id="NM_001178269.1"
/db_xref="GI:296142639"
/db_xref="GeneID:852252"
CDS 166134..167264
/locus_tag="YBL029W"
/note="Non-essential hypothetical protein"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009524.1"
/db_xref="GI:6319442"
/db_xref="SGD:S000000125"
/db_xref="GeneID:852252"
/translation="MCANIPEFDSFYENENINYNLESFAPLNCDVNSPFLPINNNDIN
VNAYGDENLTYSNFLLSYNDKLATTTAKNNSINNSNSNNNSNNNKNNNNNHNNNNLLG
NDISQMAFLLDYPSTLNEPQFAVNCKDIYRKDISTPSSLVSSLPPAKFSLSLSNSPSP
PPPSSSSLKHGEAIISNTSESSDIFADPNSFEKDTMPLTQELTLENLNNQLNYPDFTI
NAIEQDPAPSSFSSSSSSSESTVSSSRKRKPCHDSYTHSSPSSSESKKISDSRLSAEG
LAKVLNLESPEEALKRERFILGIFQNELNYPLGYKTWIRDTTKEYRTKLINQLHERVK
VKYPEYNQSILETIIRRGTYYMMQSRLRRERRMKLKERKRTT"
gene complement(167518..167838)
/locus_tag="YBL028C"
/db_xref="GeneID:852253"
mRNA complement(167518..167838)
/locus_tag="YBL028C"
/product="hypothetical protein"
/transcript_id="NM_001178268.1"
/db_xref="GI:296142640"
/db_xref="GeneID:852253"
CDS complement(167518..167838)
/locus_tag="YBL028C"
/note="hypothetical protein that may interact with
ribosomes; green fluorescent protein (GFP)-fusion protein
localizes to the nucleolus; predicted to be involved in
ribosome biogenesis"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009525.1"
/db_xref="GI:6319443"
/db_xref="SGD:S000000124"
/db_xref="GeneID:852253"
/translation="MAKSLRASSHLNAKSVKRRGVFQKAVDAREQRISDKLKEDLLKQ
KLEDLKKKEEQGIDMDVDEKKSNEEAPRKKISTSGWRDGRHHTYKKAKLMKQSKKKTS
FTRF"
gene 168423..169376
/gene="RPL19B"
/locus_tag="YBL027W"
/db_xref="GeneID:852254"
mRNA join(168423..168424,168809..169376)
/gene="RPL19B"
/locus_tag="YBL027W"
/product="ribosomal 60S subunit protein L19B"
/transcript_id="NM_001178267.1"
/db_xref="GI:296142641"
/db_xref="GeneID:852254"
CDS join(168423..168424,168809..169376)
/gene="RPL19B"
/locus_tag="YBL027W"
/note="Ribosomal 60S subunit protein L19B; rpl19a and
rpl19b single null mutations result in slow growth, while
the double null mutation is lethal; homologous to
mammalian ribosomal protein L19, no bacterial homolog;
RPL19B has a paralog, RPL19A, that arose from the whole
genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L19B"
/protein_id="NP_009526.1"
/db_xref="GI:6319444"
/db_xref="SGD:S000000123"
/db_xref="GeneID:852254"
/translation="MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKL
VKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVL
RRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAE
ARRLKNRAARDRRAQRVAEKRDALLKEDA"
rep_origin 170088..170336
/note="ARS207;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118345"
gene 170623..171038
/gene="LSM2"
/locus_tag="YBL026W"
/gene_synonym="SMX5; SNP3"
/db_xref="GeneID:852255"
mRNA join(170623..170676,170805..171038)
/gene="LSM2"
/locus_tag="YBL026W"
/gene_synonym="SMX5; SNP3"
/product="Lsm2p"
/transcript_id="NM_001178266.1"
/db_xref="GI:296142642"
/db_xref="GeneID:852255"
CDS join(170623..170676,170805..171038)
/gene="LSM2"
/locus_tag="YBL026W"
/gene_synonym="SMX5; SNP3"
/note="Lsm (Like Sm) protein; part of heteroheptameric
complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic
Lsm1p complex involved in mRNA decay; nuclear Lsm8p
complex part of U6 snRNP and possibly involved in
processing tRNA, snoRNA, and rRNA; relocalizes from
nucleus to cytoplasmic foci upon DNA replication stress"
/codon_start=1
/product="Lsm2p"
/protein_id="NP_009527.1"
/db_xref="GI:6319445"
/db_xref="SGD:S000000122"
/db_xref="GeneID:852255"
/translation="MLFFSFFKTLVDQEVVVELKNDIEIKGTLQSVDQFLNLKLDNIS
CTDEKKYPHLGSVRNIFIRGSTVRYVYLNKNMVDTNLLQDATRREVMTERK"
gene 171481..171918
/gene="RRN10"
/locus_tag="YBL025W"
/db_xref="GeneID:852256"
mRNA 171481..171918
/gene="RRN10"
/locus_tag="YBL025W"
/product="Rrn10p"
/transcript_id="NM_001178265.1"
/db_xref="GI:296142643"
/db_xref="GeneID:852256"
CDS 171481..171918
/gene="RRN10"
/locus_tag="YBL025W"
/note="Protein involved in promoting high level
transcription of rDNA, subunit of UAF (upstream activation
factor) for RNA polymerase I"
/codon_start=1
/product="Rrn10p"
/protein_id="NP_009528.1"
/db_xref="GI:6319446"
/db_xref="SGD:S000000121"
/db_xref="GeneID:852256"
/translation="MDRNVYEACSNIIKEFGTHVVSADEVLAEKIDNAVPIPFKTREE
IDADVEKDRNEGVFEGNIIPDIDLRVVHYYATQLCLNKYPHLINAFDETSLITLGLLI
EKWVKDYLTSIQTEQGRQSKVIGKGPCEFISKHIDYRHAPGNI"
gene 172534..174588
/gene="NCL1"
/locus_tag="YBL024W"
/gene_synonym="TRM4"
/db_xref="GeneID:852257"
mRNA 172534..174588
/gene="NCL1"
/locus_tag="YBL024W"
/gene_synonym="TRM4"
/product="Ncl1p"
/transcript_id="NM_001178264.1"
/db_xref="GI:296142644"
/db_xref="GeneID:852257"
CDS 172534..174588
/gene="NCL1"
/locus_tag="YBL024W"
/gene_synonym="TRM4"
/note="S-adenosyl-L-methionine-dependent tRNA:
m5C-methyltransferase, methylates cytosine to m5C at
several positions in tRNAs and intron-containing
pre-tRNAs; increases proportion of tRNALeu(CAA) with m5C
at wobble position in response to hydrogen peroxide,
causing selective translation of mRNA from genes enriched
in TTG codon; loss of NCL1 confers hypersensitivity to
oxidative stress; similar to Nop2p and human proliferation
associated nucleolar protein p120"
/codon_start=1
/product="Ncl1p"
/protein_id="NP_009529.1"
/db_xref="GI:6319447"
/db_xref="SGD:S000000120"
/db_xref="GeneID:852257"
/translation="MARRKNFKKGNKKTFGARDDSRAQKNWSELVKENEKWEKYYKTL
ALFPEDQWEEFKKTCQAPLPLTFRITGSRKHAGEVLNLFKERHLPNLTNVEFEGEKIK
APVELPWYPDHLAWQLDVPKTVIRKNEQFAKTQRFLVVENAVGNISRQEAVSMIPPIV
LEVKPHHTVLDMCAAPGSKTAQLIEALHKDTDEPSGFVVANDADARRSHMLVHQLKRL
NSANLMVVNHDAQFFPRIRLHGNSNNKNDVLKFDRILCDVPCSGDGTMRKNVNVWKDW
NTQAGLGLHAVQLNILNRGLHLLKNNGRLVYSTCSLNPIENEAVVAEALRKWGDKIRL
VNCDDKLPGLIRSKGVSKWPVYDRNLTEKTKGDEGTLDSFFSPSEEEASKFNLQNCMR
VYPHQQNTGGFFITVFEKVEDSTEAATEKLSSETPALESEGPQTKKIKVEEVQKKERL
PRDANEEPFVFVDPQHEALKVCWDFYGIDNIFDRNTCLVRNATGEPTRVVYTVCPALK
DVIQANDDRLKIIYSGVKLFVSQRSDIECSWRIQSESLPIMKHHMKSNRIVEANLEML
KHLLIESFPNFDDIRSKNIDNDFVEKMTKLSSGCAFIDVSRNDPAKENLFLPVWKGNK
CINLMVCKEDTHELLYRIFGIDANAKATPSAEEKEKEKETTESPAETTTGTSTEAPSA
AN"
gene complement(174920..177526)
/gene="MCM2"
/locus_tag="YBL023C"
/db_xref="GeneID:852258"
mRNA complement(174920..177526)
/gene="MCM2"
/locus_tag="YBL023C"
/product="Mcm2p"
/transcript_id="NM_001178263.1"
/db_xref="GI:296142645"
/db_xref="GeneID:852258"
CDS complement(174920..177526)
/gene="MCM2"
/locus_tag="YBL023C"
/note="Protein involved in DNA replication; component of
the Mcm2-7 hexameric complex that binds chromatin as a
part of the pre-replicative complex; relative distribution
to the nucleus increases upon DNA replication stress"
/codon_start=1
/product="Mcm2p"
/protein_id="NP_009530.1"
/db_xref="GI:6319448"
/db_xref="SGD:S000000119"
/db_xref="GeneID:852258"
/translation="MSDNRRRRREEDDSDSENELPPSSPQQHFRGGMNPVSSPIGSPD
MINPEGDDNEVDDVPDIDEVEEQMNEVDLMDDNMYEDYAADHNRDRYDPDQVDDREQQ
ELSLSERRRIDAQLNERDRLLRNVAYIDDEDEEQEGAAQLDEMGLPVQRRRRRRQYED
LENSDDDLLSDMDIDPLREELTLESLSNVKANSYSEWITQPNVSRTIARELKSFLLEY
TDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAM
EATELHYPDYARIHSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQL
KYVKFNCLKCGSILGPFFQDSNEEIRISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQE
APGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAKNGFPVFATI
IEANSIKRREGNTANEGEEGLDVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGH
RDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFA
TGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAM
EQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCV
VRDLVDEEADERLATFVVDSHVRSHPENDEDREGEELKNNGESAIEQGEDEINEQLNA
RQRRLQRQRKKEEEISPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESI
STGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDAQKVSVRRQ
LRRSFAIYTLGH"
gene complement(177874..181275)
/gene="PIM1"
/locus_tag="YBL022C"
/db_xref="GeneID:852259"
mRNA complement(177874..181275)
/gene="PIM1"
/locus_tag="YBL022C"
/product="Pim1p"
/transcript_id="NM_001178262.1"
/db_xref="GI:296142646"
/db_xref="GeneID:852259"
CDS complement(177874..181275)
/gene="PIM1"
/locus_tag="YBL022C"
/EC_number="3.4.21.-"
/note="ATP-dependent Lon protease, involved in degradation
of misfolded proteins in mitochondria; required for
biogenesis and maintenance of mitochondria"
/codon_start=1
/product="Pim1p"
/protein_id="NP_009531.1"
/db_xref="GI:6319449"
/db_xref="SGD:S000000118"
/db_xref="GeneID:852259"
/translation="MLRTRTTKTLSTVARTTRAIQYYRSIAKTAAVSQRRFASTLTVR
DVENIKPSHIIKSPTWQEFQHQLKDPRYMEHFAQLDAQFARHFMATNSGKSILAKDDS
TSQKKDEDVKIVPDEKDTDNDVEPTRDDEIVNKDQEGEASKNSRSSASGGGQSSSSRS
DSGDGSSKQKPPKDVPEVYPQMLALPIARRPLFPGFYKAVVISDERVMKAIKEMLDRQ
QPYIGAFMLKNSEEDTDVITDKNDVYDVGVLAQITSAFPSKDEKTGTETMTALLYPHR
RIKIDELFPPNEEKEKSKEQAKDTDTETTVVEDANNPEDQESTSPATPKLEDIVVERI
PDSELQHHKRVEATEEESEELDDIQEGEDINPTEFLKNYNVSLVNVLNLEDEPFDRKS
PVINALTSEILKVFKEISQLNTMFREQIATFSASIQSATTNIFEEPARLADFAAAVSA
GEEDELQDILSSLNIEHRLEKSLLVLKKELMNAELQNKISKDVETKIQKRQREYYLME
QLKGIKRELGIDDGRDKLIDTYKERIKSLKLPDSVQKIFDDEITKLSTLETSMSEFGV
IRNYLDWLTSIPWGKHSKEQYSIPRAKKILDEDHYGMVDVKDRILEFIAVGKLLGKVD
GKIICFVGPPGVGKTSIGKSIARALNRKFFRFSVGGMTDVAEIKGHRRTYIGALPGRV
VQALKKCQTQNPLILIDEIDKIGHGGIHGDPSAALLEVLDPEQNNSFLDNYLDIPIDL
SKVLFVCTANSLETIPRPLLDRMEVIELTGYVAEDKVKIAEQYLVPSAKKSAGLENSH
VDMTEDAITALMKYYCRESGVRNLKKHIEKIYRKAALQVVKKLSIEDSPTSSADSKPK
ESVSSEEKAENNAKSSSEKTKDNNSEKTSDDIEALKTSEKINVSISQKNLKDYVGPPV
YTTDRLYETTPPGVVMGLAWTNMGGCSLYVESVLEQPLHNCKHPTFERTGQLGDVMKE
SSRLAYSFAKMYLAQKFPENRFFEKASIHLHCPEGATPKDGPSAGVTMATSFLSLALN
KSIDPTVAMTGELTLTGKVLRIGGLREKAVAAKRSGAKTIIFPKDNLNDWEELPDNVK
EGLEPLAADWYNDIFQKLFKDVNTKEGNSVWKAEFEILDAKKEKD"
gene complement(181660..182094)
/gene="HAP3"
/locus_tag="YBL021C"
/db_xref="GeneID:852260"
mRNA complement(181660..182094)
/gene="HAP3"
/locus_tag="YBL021C"
/product="Hap3p"
/transcript_id="NM_001178261.1"
/db_xref="GI:296142647"
/db_xref="GeneID:852260"
CDS complement(181660..182094)
/gene="HAP3"
/locus_tag="YBL021C"
/note="Subunit of the heme-activated, glucose-repressed
Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional
activator and global regulator of respiratory gene
expression; contains sequences contributing to both
complex assembly and DNA binding"
/codon_start=1
/product="Hap3p"
/protein_id="NP_009532.1"
/db_xref="GI:6319450"
/db_xref="SGD:S000000117"
/db_xref="GeneID:852260"
/translation="MNTNESEHVSTSPEDTQENGGNASSSGSLQQISTLREQDRWLPI
NNVARLMKNTLPPSAKVSKDAKECMQECVSELISFVTSEASDRCAADKRKTINGEDIL
ISLHALGFENYAEVLKIYLAKYRQQQALKNQLMYEQDDEEVP"
gene 182401..184125
/gene="RFT1"
/locus_tag="YBL020W"
/db_xref="GeneID:852261"
mRNA 182401..184125
/gene="RFT1"
/locus_tag="YBL020W"
/product="Rft1p"
/transcript_id="NM_001178260.1"
/db_xref="GI:296142648"
/db_xref="GeneID:852261"
CDS 182401..184125
/gene="RFT1"
/locus_tag="YBL020W"
/note="Essential integral membrane protein that is
required for translocation of Man5GlcNac2-PP-Dol from the
cytoplasmic side to the lumenal side of the ER membrane
but is not the flippase; mutation is suppressed by
expression of human p53 protein"
/codon_start=1
/product="Rft1p"
/protein_id="NP_009533.1"
/db_xref="GI:6319451"
/db_xref="SGD:S000000116"
/db_xref="GeneID:852261"
/translation="MAKKNSQLPSTSEQILERSTTGATFLMMGQLFTKLVTFILNNLL
IRFLSPRIFGITAFLEFIQGTVLFFSRDAIRLSTLRISDSGNGIIDDDDEEEYQETHY
KSKVLQTAVNFAYIPFWIGFPLSIGLIAWQYRNINAYFITLPFFRWSIFLIWLSIIVE
LLSEPFFIVNQFMLNYAARSRFESIAVTTGCIVNFIVVYAVQQSRYPMGVVTSDIDKE
GIAILAFALGKLAHSITLLACYYWDYLKNFKPKKLFSTRLTKIKTRENNELKKGYPKS
TSYFFQNDILQHFKKVYFQLCFKHLLTEGDKLIINSLCTVEEQGIYALLSNYGSLLTR
LLFAPIEESLRLFLARLLSSHNPKNLKLSIEVLVNLTRFYIYLSLMIIVFGPANSSFL
LQFLIGSKWSTTSVLDTIRVYCFYIPFLSLNGIFEAFFQSVATGDQILKHSYFMMAFS
GIFLLNSWLLIEKLKLSIEGLILSNIINMVLRILYCGVFLNKFHRELFTDSSFFFNFK
DFKTVIIAGSTICLLDWWFIGYVKNLQQFVVNVLFAMGLLALILVKERQTIQSFINKR
AVSNSKDV"
gene 184353..185915
/gene="APN2"
/locus_tag="YBL019W"
/gene_synonym="ETH1"
/db_xref="GeneID:852262"
mRNA 184353..185915
/gene="APN2"
/locus_tag="YBL019W"
/gene_synonym="ETH1"
/product="DNA-(apurinic or apyrimidinic site) lyase APN2"
/transcript_id="NM_001178259.1"
/db_xref="GI:296142649"
/db_xref="GeneID:852262"
CDS 184353..185915
/gene="APN2"
/locus_tag="YBL019W"
/gene_synonym="ETH1"
/EC_number="4.2.99.18"
/note="Class II abasic (AP) endonuclease involved in
repair of DNA damage; homolog of human HAP1 and E. coli
exoIII"
/codon_start=1
/product="DNA-(apurinic or apyrimidinic site) lyase APN2"
/protein_id="NP_009534.1"
/db_xref="GI:6319452"
/db_xref="SGD:S000000115"
/db_xref="GeneID:852262"
/translation="MSSSENTLLDGKSENTIRFLTFNVNGIRTFFHYQPFSQMNQSLR
SVFDFFRADIITFQELKTEKLSISKWGRVDGFYSFISIPQTRKGYSGVGCWIRIPEKN
HPLYHALQVVKAEEGITGYLTIKNGKHSAISYRNDVNQGIGGYDSLDPDLDEKSALEL
DSEGRCVMVELACGIVIISVYCPANSNSSEEGEMFRLRFLKVLLRRVRNLDKIGKKIV
LMGDVNVCRDLIDSADTLEQFSIPITDPMGGTKLEAQYRDKAIQFIINPDTPHRRIFN
QILADSLLPDASKRGILIDTTRLIQTRNRLKMYTVWNMLKNLRPSNYGSRIDFILVSL
KLERCIKAADILPDILGSDHCPVYSDLDILDDRIEPGTTQVPIPKFEARYKYNLRNHN
VLEMFAKKDTNKESNKQKYCVSKVMNTKKNSNIKNKSLDSFFQKVNGEKDDRIKESSE
IPQQAKKRISTPKLNFKDVFGKPPLCRHGEESMLKTSKTSANPGRKFWICKRSRGDSN
NTESSCGFFQWV"
gene complement(185998..186474)
/gene="POP8"
/locus_tag="YBL018C"
/db_xref="GeneID:852263"
mRNA complement(join(185998..186352,186428..186474))
/gene="POP8"
/locus_tag="YBL018C"
/product="Pop8p"
/transcript_id="NM_001178258.1"
/db_xref="GI:296142650"
/db_xref="GeneID:852263"
CDS complement(join(185998..186352,186428..186474))
/gene="POP8"
/locus_tag="YBL018C"
/EC_number="3.1.26.5"
/note="Subunit of both RNase MRP and nuclear RNase P;
RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves
tRNA precursors to generate mature 5' ends and facilitates
turnover of nuclear RNAs"
/codon_start=1
/product="Pop8p"
/protein_id="NP_009535.1"
/db_xref="GI:6319453"
/db_xref="SGD:S000000114"
/db_xref="GeneID:852263"
/translation="MGKKTFREWQYFKLSITSFDQDVDDAHAIDQMTWRQWLNNALKR
SYGIFGEGVEYSFLHVDDKLAYIRVNHADKDTFSSSISTYISTDELVGSPLTVSILQE
SSSLRLLEVTDDDRLWLKKVMEEEEQDCKCI"
gene complement(186844..191583)
/gene="PEP1"
/locus_tag="YBL017C"
/gene_synonym="VPS10; VPT1"
/db_xref="GeneID:852264"
mRNA complement(186844..191583)
/gene="PEP1"
/locus_tag="YBL017C"
/gene_synonym="VPS10; VPT1"
/product="Pep1p"
/transcript_id="NM_001178257.1"
/db_xref="GI:296142651"
/db_xref="GeneID:852264"
CDS complement(186844..191583)
/gene="PEP1"
/locus_tag="YBL017C"
/gene_synonym="VPS10; VPT1"
/note="Type I transmembrane sorting receptor for multiple
vacuolar hydrolases; cycles between the late-Golgi and
prevacuolar endosome-like compartments"
/codon_start=1
/product="Pep1p"
/protein_id="NP_009536.1"
/db_xref="GI:6319454"
/db_xref="SGD:S000000113"
/db_xref="GeneID:852264"
/translation="MILLHFVYSLWALLLIPLTNAEEFTPKVTKTIAQDSFDILSFDD
SNTLIRKQDTSVTISFDDGETWEKVEGIEGEITWIYIDPFNRHDRAVATAMNGSYLYI
TNDQGKSWERITLPDSGESISPRECYIETHPLNKNYFLAKCNYCEKTEVNNDNEENSG
DEEGQFEIFNITRCTDKVFASNDGGKSFSEIKSSLERNENSPISISDCGFAKTSKDSD
LESSDTSIICLFQNMQLIMDEFSSPYTESKLVLTTDWGKSLKEFDQFKDKVVNGYRIL
KSHMVVLTQGDRYNDMSSMDVWVSNDLSNFKMAYMPTQLRHSMQGEIYEDAMGRIILP
MSRERSDQEEDKGIVSEILISDSQGLKFSPIPWTANEVFGYINFYQPTYLKGTMIASL
YPLSRRRNRKGKAKGVKSKGVTKISVDNGLTWTMLKVVDPDNADSFDCDITDFENCSL
QNMFYTREGSTPTAGILMTTGIVGDGSVFDWGDQRTFISRDGGLTWKLAFDFPCLYAV
GDYGNVIVAIPYNADEDDDPQSEFYYSLDQGKTWTEYQLETTIYPNEVMNTTPDGSGA
KFILNGFTLAHMDGTTNFIYAIDFSTAFNDKTCEENDFEDWNLAEGKCVNGVKYKIRR
RKQDAQCLVKKVFEDLQLFETACDKCTEADYECAFEFVRDATGKCVPDYNLIVLSDVC
DKTKKKTVPVKPLQLVKGDKCKKPMTVKSVDISCEGVPKKGTNDKEIVVTENKFDFKI
QFYQYFDTVTDESLLMINSRGEAYISHDGGQTIKRFDSNGETIIEVVFNPYYNSSAYL
FGSKGSIFSTHDRGYSFMTAKLPEARQLGMPLDFNAKAQDTFIYYGGKNCESILSPEC
HAVAYLTNDGGETFTEMLDNAIHCEFAGSLFKYPSNEDMVMCQVKEKSSQTRSLVSST
DFFQDDKNTVFENIIGYLSTGGYIIVAVPHENNELRAYVTIDGTEFAEAKFPYDEDVG
KQEAFTILESEKGSIFLHLATNLVPGRDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVD
FEKIQGLEGIILTNIVSNSDKVAENKEDKQLKTKITFNEGSDWNFLKPPKRDSEGKKF
SCSSKSLDECSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGPNLLPYKECSTFFTT
DGGETWAEVKKTPHQWEYGDHGGILVLVPENSETDSISYSTDFGKTWKDYKFCADKVL
VKDITTVPRDSALRFLLFGEAADIGGSSFRTYTIDFRNIFERQCDFDITGKESADYKY
SPLGSKSNCLFGHQTEFLRKTDENCFIGNIPLSEFSRNIKNCSCTRQDFECDYNFYKA
NDGTCKLVKGLSPANAADVCKKEPDLIEYFESSGYRKIPLSTCEGGLKLDAPSSPHAC
PGKEKEFKEKYSVSAGPFAFIFISILLIIFFAAWFVYDRGIRRNGGFARFGEIRLGDD
GLIENNNTDRVVNNIVKSGFYVFSNIGSLLQHTKTNIAHAISKIRGRFGNRTGPSYSS
LIHDQFLDEADDLLAGHDEDANDLSSFMDQGSNFEIEEDDVPTLEEEHTSYTDQPTTT
DVPDTLPEGNEENIDRPDSTAPSNENQ"
gene 192451..193512
/gene="FUS3"
/locus_tag="YBL016W"
/gene_synonym="DAC2"
/db_xref="GeneID:852265"
mRNA 192451..193512
/gene="FUS3"
/locus_tag="YBL016W"
/gene_synonym="DAC2"
/product="Fus3p"
/transcript_id="NM_001178256.1"
/db_xref="GI:296142652"
/db_xref="GeneID:852265"
CDS 192451..193512
/gene="FUS3"
/locus_tag="YBL016W"
/gene_synonym="DAC2"
/EC_number="2.7.11.24"
/note="Mitogen-activated serine/threonine protein kinase
involved in mating; phosphoactivated by Ste7p; substrates
include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive
growth during mating by phosphorylating Tec1p, promoting
its degradation"
/codon_start=1
/product="Fus3p"
/protein_id="NP_009537.1"
/db_xref="GI:6319455"
/db_xref="SGD:S000000112"
/db_xref="GeneID:852265"
/translation="MPKRIVYNISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKI
EPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHR
VISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLAR
IIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFL
RRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFP
RVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEPEGEPIPPSFFEFDHY
KEALTTKDLKKLIWNEIFS"
gene 194122..195702
/gene="ACH1"
/locus_tag="YBL015W"
/db_xref="GeneID:852266"
mRNA 194122..195702
/gene="ACH1"
/locus_tag="YBL015W"
/product="Ach1p"
/transcript_id="NM_001178255.1"
/db_xref="GI:296142653"
/db_xref="GeneID:852266"
CDS 194122..195702
/gene="ACH1"
/locus_tag="YBL015W"
/EC_number="3.1.2.1"
/note="Protein with CoA transferase activity, particularly
for CoASH transfer from succinyl-CoA to acetate; has minor
acetyl-CoA-hydrolase activity; phosphorylated; required
for acetate utilization and for diploid pseudohyphal
growth"
/codon_start=1
/product="Ach1p"
/protein_id="NP_009538.1"
/db_xref="GI:6319456"
/db_xref="SGD:S000000111"
/db_xref="GeneID:852266"
/translation="MTISNLLKQRVRYAPYLKKVKEAHELIPLFKNGQYLGWSGFTGV
GTPKAVPEALIDHVEKNNLQGKLRFNLFVGASAGPEENRWAEHDMIIKRAPHQVGKPI
AKAINQGRIEFFDKHLSMFPQDLTYGFYTRERKDNKILDYTIIEATAIKEDGSIVPGP
SVGGSPEFITVSDKVIIEVNTATPSFEGIHDIDMPVNPPFRKPYPYLKVDDKCGVDSI
PVDPEKVVAIVESTMRDQVPPNTPSDDMSRAIAGHLVEFFRNEVKHGRLPENLLPLQS
GIGNIANAVIEGLAGAQFKHLTVWTEVLQDSFLDLFENGSLDYATATSVRLTEKGFDR
AFANWENFKHRLCLRSQVVSNNPEMIRRLGVIAMNTPVEVDIYAHANSTNVNGSRMLN
GLGGSADFLRNAKLSIMHAPSARPTKVDPTGISTIVPMASHVDQTEHDLDILVTDQGL
ADLRGLSPKERAREIINKCAHPDYQALLTDYLDRAEHYAKKHNCLHEPHMLKNAFKFH
TNLAEKGTMKVDSWEPVD"
LTR complement(197016..197320)
/note="Ty1 LTR"
/db_xref="SGD:S000006796"
gene 197494..197567
/locus_tag="tI(AAU)B"
/db_xref="GeneID:852267"
tRNA 197494..197567
/locus_tag="tI(AAU)B"
/product="tRNA-Ile"
/note="Isoleucine tRNA (tRNA-Ile), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006600"
/db_xref="GeneID:852267"
gene complement(197629..197699)
/locus_tag="tG(GCC)B"
/db_xref="GeneID:852268"
tRNA complement(197629..197699)
/locus_tag="tG(GCC)B"
/product="tRNA-Gly"
/note="Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006574"
/db_xref="GeneID:852268"
LTR 197714..198054
/note="Ty3 LTR"
/db_xref="SGD:S000006797"
rep_origin 198232..198472
/note="ARS231;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118997"
gene complement(199064..201748)
/gene="RRN6"
/locus_tag="YBL014C"
/db_xref="GeneID:852269"
mRNA complement(199064..201748)
/gene="RRN6"
/locus_tag="YBL014C"
/product="Rrn6p"
/transcript_id="NM_001178254.2"
/db_xref="GI:330443416"
/db_xref="GeneID:852269"
CDS complement(199064..201748)
/gene="RRN6"
/locus_tag="YBL014C"
/note="Component of the core factor (CF) rDNA
transcription factor complex; CF is required for
transcription of 35S rRNA genes by RNA polymerase I and is
composed of Rrn6p, Rrn7p, and Rrn11p"
/codon_start=1
/product="Rrn6p"
/protein_id="NP_009539.2"
/db_xref="GI:330443417"
/db_xref="SGD:S000000110"
/db_xref="GeneID:852269"
/translation="MSEGQIPSSDVLGSQLGVGVQGASLYCPQENYTTKKQEKPQWLR
PVDDTLAEDALDLHIVVKSLLCDTAIRYISDDKVLQESDADDDLITSDIDEDTDNQGD
TSIVVNPVIPVVPKDVHFFKKVDVGNDSMFGVNCDTPVSFQDYIPSDLLRNLDDTLQE
STNSSRPMQDAFFWDPTVANRLDSQYIQTASDLRNYRDGTEIIAYASGKTGSVLNIAV
LTRQNTLHLNRHNNVTSIELHSPIKSIKIPGASESIGRRSNLVGIITENSFQIFRIES
VHSRSCDVMVSSSEPLYFVEIDDLQVVDFAFNPWDLQQFAIIDIKGNWSIGRIPKNFN
NNNKRKLQLIDNLHGTIFDPEELSSWKRIEWFSHFQKILVFDRSKMIEIDFMNNWQTE
VVQAKAWSNIRDYKRIDDKNGILLTSREIIIVGASESNDPVRRISWKHDLDPDDTTLR
ITVQKVKKPDHILLVAFVYSMRHKRIYMHVFSHRKANLFQSLGCSTVLEIPGGTPTGI
ETILTLDHIDDESRREEDADENFELVVDFLVKLRNSSEVYYYALSNTQNSEPNKQETP
IIVDHPEWASLFNNADEREKESIGALVSQIKLKERERISRVQNLIEHENSHDEDKYLQ
DLGYRLSIATNELLESWQKTKDESILSGSLSHSKLKNLLENSDSFASIPEFSSLLDQF
FQYYQDQDVTFIGFEKLLHLFLHEDVPGLDIFYNKLLQCWVLVSPQAELLTKEIVKDI
IWSLARLEKPSLFEPIQNEISRSLSGPYQDIISSWDMDDINEEDESNEFNFDSQFSAP
FNGRPPFNLNSQSQIPTIKSSQSSGLARRKRILKTQSQKATPLSQSTQNLSVLPDSMT
PAFTLMQPPSSQISFVNDSQPRNSQKAKKKKKRIRGFG"
gene 202056..203261
/gene="FMT1"
/locus_tag="YBL013W"
/db_xref="GeneID:852270"
mRNA 202056..203261
/gene="FMT1"
/locus_tag="YBL013W"
/product="Fmt1p"
/transcript_id="NM_001178253.1"
/db_xref="GI:296142655"
/db_xref="GeneID:852270"
CDS 202056..203261
/gene="FMT1"
/locus_tag="YBL013W"
/EC_number="2.1.2.9"
/note="Methionyl-tRNA formyltransferase, catalyzes the
formylation of initiator Met-tRNA in mitochondria;
potential Cdc28p substrate"
/codon_start=1
/product="Fmt1p"
/protein_id="NP_009540.2"
/db_xref="GI:41629674"
/db_xref="SGD:S000000109"
/db_xref="GeneID:852270"
/translation="MVKMRRITPTRLLFTCRYISNNASPPVQPLNVLFFGSDTFSNFS
LQALNELRQNNGSCGIVDNIQVVTRSPKWCGRQKSILKYPPIFDMAEKLQLPRPITCD
TKQEMLALSKLTPSRQGNPENDGSGAPFNAIIAVSFGKLIPGDLIRAVPLALNVHPSL
LPRHKGSAPIQRALLEGDTYTGVTIQTLHPDRFDHGAIVAQTEPLAIATMLSKGRVND
STADFNSEGLPRRTAILMDQLGALGAQLLGQTLRERLYLPQNRVQAPTAYKPSYAHRI
TTEDKRIHWARDSAAELLNKLETLGPLHAFKEATAARKDAQNSVLKRILFHECKVMRD
ARLDNGSKPGMFKYDDIKDCILVTCRGNLLLCVSRLQFEGFAVERAGQFMARLRKRCG
ALSEKLVFL"
gene 203538..205817
/gene="SCT1"
/locus_tag="YBL011W"
/gene_synonym="GAT2"
/db_xref="GeneID:852271"
mRNA 203538..205817
/gene="SCT1"
/locus_tag="YBL011W"
/gene_synonym="GAT2"
/product="bifunctional
glycerol-3-phosphate/glycerone-phosphate O-acyltransferase
SCT1"
/transcript_id="NM_001178251.1"
/db_xref="GI:296142656"
/db_xref="GeneID:852271"
CDS 203538..205817
/gene="SCT1"
/locus_tag="YBL011W"
/gene_synonym="GAT2"
/EC_number="2.3.1.42"
/EC_number="2.3.1.15"
/note="Glycerol 3-phosphate/dihydroxyacetone phosphate
dual substrate-specific sn-1 acyltransferase of the
glycerolipid biosynthesis pathway, prefers 16-carbon fatty
acids, similar to Gpt2p, gene is constitutively
transcribed"
/codon_start=1
/product="bifunctional
glycerol-3-phosphate/glycerone-phosphate O-acyltransferase
SCT1"
/protein_id="NP_009542.1"
/db_xref="GI:6319459"
/db_xref="SGD:S000000107"
/db_xref="GeneID:852271"
/translation="MPAPKLTEKFASSKSTQKTTNYSSIEAKSVKTSADQAYIYQEPS
ATKKILYSIATWLLYNIFHCFFREIRGRGSFKVPQQGPVIFVAAPHANQFVDPVILMG
EVKKSVNRRVSFLIAESSLKQPPIGFLASFFMAIGVVRPQDNLKPAEGTIRVDPTDYK
RVIGHDTHFLTDCMPKGLIGLPKSMGFGEIQSIESDTSLTLRKEFKMAKPEIKTALLT
GTTYKYAAKVDQSCVYHRVFEHLAHNNCIGIFPEGGSHDRTNLLPLKAGVAIMALGCM
DKHPDVNVKIVPCGMNYFHPHKFRSRAVVEFGDPIEIPKELVAKYHNPETNRDAVKEL
LDTISKGLQSVTVTCSDYETLMVVQTIRRLYMTQFSTKLPLPLIVEMNRRMVKGYEFY
RNDPKIADLTKDIMAYNAALRHYNLPDHLVEEAKVNFAKNLGLVFFRSIGLCILFSLA
MPGIIMFSPVFILAKRISQEKARTALSKSTVKIKANDVIATWKILIGMGFAPLLYIFW
SVLITYYLRHKPWNKIYVFSGSYISCVIVTYSALIVGDIGMDGFKSLRPLVLSLTSPK
GLQKLQKDRRNLAERIIEVVNNFGSELFPDFDSAALREEFDVIDEEEEDRKTSELNRR
KMLRKQKIKRQEKDSSSPIISQRDNHDAYEHHNQDSDGVSLVNSDNSLSNIPLFSSTF
HRKSESSLASTSVAPSSSSEFEVENEILEEKNGLASKIAQAVLNKRIGENTAREEEEE
EEEEEEEEEEEEEGKEGDA"
gene complement(206107..206949)
/locus_tag="YBL010C"
/db_xref="GeneID:852273"
mRNA complement(206107..206949)
/locus_tag="YBL010C"
/product="hypothetical protein"
/transcript_id="NM_001178250.1"
/db_xref="GI:296142657"
/db_xref="GeneID:852273"
CDS complement(206107..206949)
/locus_tag="YBL010C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein colocalizes with clathrin-coated
vesicles"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009543.1"
/db_xref="GI:6319461"
/db_xref="SGD:S000000106"
/db_xref="GeneID:852273"
/translation="MSDRDQIEPVTNALDAESDSSDDFGNFSDASVENDLYNQNSTLT
TSSESVVDNCLNKILPKGEFDLEEETIKNDCFKLSKLIEDERPHVIYEQLVQLDPVLQ
PFIWNKSHIRRNLLHILRLSDNNGSEGVGTKREEEPLNDELFKRICDAVEKNEQTATG
LFLRDNFKIDYTPPMTLKSLQKEEEREQEQHIPQLLMADFTSMDEESLRQYHDTLCQS
IDFLVSKSRSLKKQQRDLLKDKTTFENVVTNLTGHTQRLQRDEIALYNKKRNKKKRFS
WVGY"
gene 207194..209224
/gene="ALK2"
/locus_tag="YBL009W"
/db_xref="GeneID:852274"
mRNA 207194..209224
/gene="ALK2"
/locus_tag="YBL009W"
/product="Alk2p"
/transcript_id="NM_001178249.1"
/db_xref="GI:296142658"
/db_xref="GeneID:852274"
CDS 207194..209224
/gene="ALK2"
/locus_tag="YBL009W"
/EC_number="2.7.11.1"
/note="Protein kinase; accumulation and phosphorylation
are periodic during the cell cycle; phosphorylated in
response to DNA damage; contains characteristic motifs for
degradation via the APC pathway; ALK2 has a paralog, ALK1,
that arose from the whole genome duplication; similar to
mammalian haspins"
/codon_start=1
/product="Alk2p"
/protein_id="NP_009544.1"
/db_xref="GI:6319462"
/db_xref="SGD:S000000105"
/db_xref="GeneID:852274"
/translation="MNFDAVADQQMTDRRYFALEVAESDDADSSLNSSSMGSPAVDVG
RKVYKITSHKGSAEDESQSFFTSSDSPTSKTRPVGKTIENDDYYGKRSSTGSSLKQLF
NKININDTAHSSNKENVSQSVLSENKLLSPSKRLSKQGLTKVTNSKFRTPLRPISNQS
TLSRDEPVKDFRSLKFRSGSDFKCWGDEKTSSHVHSSSVNSVNSFTSTTSSSKWKFWK
NDNLLSRSLSSRSVNDQDPNFVQPKPTNSLQKKSSISSFHNSIFGGGKHTEKKRNSGF
IMPDHQSTKELNHKHSSSNLSFRSLKHKTSHSSLNKLKVRRKGNTQELNHPIKKTCQI
SLPVPDQVSKDKIQLKLKNSTSLASLSSEVTPINTLDYNDSILQQILQLCDVKYILHD
LREAQSLGLFTLNTRSVQLSHNFWQTYHSDMQTSLICKKVCLGALSDLTTSNLISLHE
LKSLRLIQGTSGVANLLQAYVVPSNQCENDQNLILYLFFKYQGTPLSRCSNIDYSQAL
SIFWQCSSILYVAESKFQLEHRNLTLDHILIDSKGNVTLIDMKCCRFLNIDNNKASYT
RLDHHYFFQGRGTLQFEIYELMRSMLPQPISWATFEPRTNLLWLYHLSSSLLKMAKKA
VVSGALNREENILIELTHLLDPARKHSKTIFKKELVIRTCGDLLSLKGEIMQ"
gene 209409..209648
/locus_tag="YBL008W-A"
/db_xref="GeneID:1466442"
mRNA 209409..209648
/locus_tag="YBL008W-A"
/product="hypothetical protein"
/transcript_id="NM_001184539.1"
/db_xref="GI:296142659"
/db_xref="GeneID:1466442"
CDS 209409..209648
/locus_tag="YBL008W-A"
/note="hypothetical protein; identified by fungal homology
and RT-PCR"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878046.1"
/db_xref="GI:33438764"
/db_xref="SGD:S000028529"
/db_xref="GeneID:1466442"
/translation="MKMNPCTVILCKSLFFFCLFQVDCYCNRKNIQNQSSRIATKIKR
SYWFRWQKHIILANIHKIIKAYQRSIIKLPVTKGL"
gene 209653..212175
/gene="HIR1"
/locus_tag="YBL008W"
/db_xref="GeneID:852275"
mRNA 209653..212175
/gene="HIR1"
/locus_tag="YBL008W"
/product="Hir1p"
/transcript_id="NM_001178248.2"
/db_xref="GI:330443418"
/db_xref="GeneID:852275"
CDS 209653..212175
/gene="HIR1"
/locus_tag="YBL008W"
/note="Subunit of the HIR complex, a nucleosome assembly
complex involved in regulation of histone gene
transcription; contributes to nucleosome formation,
heterochromatic gene silencing, and formation of
functional kinetochores"
/codon_start=1
/product="Hir1p"
/protein_id="NP_009545.2"
/db_xref="GI:330443419"
/db_xref="SGD:S000000104"
/db_xref="GeneID:852275"
/translation="MKVVKFPWLAHREESRKYEIYTVDVSHDGKRLATGGLDGKIRIW
SIDSILRCMELESLTPEIPLPQDLQMPLCSMSRHTGSITCVKFSPDGKYLASGSDDRI
LLIWALDEEQSSQPAFGSEHEREHWTVRKRLVAHDNDIQDICWAPDSSILVTVGLDRS
VIVWNGSTFEKLKRFDVHQSLVKGVVFDPANKYFATTSDDRTMKIFRYHKTGDISFTI
EHIITEPFKESPLTTYFRRPSWSPDGQHIAVPNATNGPVSSVAIVNRGTWDTNVSLIG
HDAPTEVARFNPRLFERNAGVKQKKDDDPENALVGQNDDKVHHFDKNIDSVVATAGQD
KSLAVWSTSRPRPILVAFDIANKSITDMSWNPDGSLLFVASLDSSITLFKFENNELGK
PIPLEKNMEQLYRYGVDKDSLDFPESINQLLLEDQTKSFKHTKISTSKLGENHPTLAT
NSASNQKDNNDASVSRSEHINILIPKRKKDAILNKAVTLKSGKKRVAPTLISTSSSSP
FSNGIKKPTLDSKRIENNVKSSTKTINSKNTLLNVPEGVEKKISISSFPLPRLGIHSL
IMGTKERSAWKISNSELENDDADNAGGKGSDGTSNSIDDIAVLSEEENDFHRMTLNAK
LTQEKIWSEEPTTRCLLQSDVIPDTDVVVLEGGSLDDIAVLEIRNGVERSIQFDSEAL
LDNPTRILGYQGGKRTIETFIPEVIICAIGSKDCKCWCLASANGSIYILSYNGQQRIP
KICLGHKVIKMVTSSKYLLVLTERGLFFAWDLLDLKLVLRNVPILPILNGQPIHGNKV
RINKVIKCFRLDGSSCDLLLEVGDPKNVYKWTKDLGCWSLYK"
gene complement(212632..216366)
/gene="SLA1"
/locus_tag="YBL007C"
/db_xref="GeneID:852276"
mRNA complement(212632..216366)
/gene="SLA1"
/locus_tag="YBL007C"
/product="Sla1p"
/transcript_id="NM_001178247.1"
/db_xref="GI:296142661"
/db_xref="GeneID:852276"
CDS complement(212632..216366)
/gene="SLA1"
/locus_tag="YBL007C"
/note="Cytoskeletal protein binding protein required for
assembly of the cortical actin cytoskeleton; interacts
with proteins regulating actin dynamics and proteins
required for endocytosis; found in the nucleus and cell
cortex; has 3 SH3 domains"
/codon_start=1
/product="Sla1p"
/protein_id="NP_009546.1"
/db_xref="GI:6319464"
/db_xref="SGD:S000000103"
/db_xref="GeneID:852276"
/translation="MTVFLGIYRAVYAYEPQTPEELAIQEDDLLYLLQKSDIDDWWTV
KKRVIGSDSEEPVGLVPSTYIEEAPVLKKVRAIYDYEQVQNADEELTFHENDVFDVFD
DKDADWLLVKSTVSNEFGFIPGNYVEPENGSTSKQEQAPAAAEAPAATPAAAPASAAV
LPTNFLPPPQHNDRARMMQSKEDQAPDEDEEGPPPAMPARPTATTETTDATAAAVRSR
TRLSYSDNDNDDEEDDYYYNSNSNNVGNHEYNTEYHSWNVTEIEGRKKKKAKLSIGNN
KINFIPQKGTPHEWSIDKLVSYDNEKKHMFLEFVDPYRSLELHTGNTTTCEEIMNIIG
EYKGASRDPGLREVEMASKSKKRGIVQYDFMAESQDELTIKSGDKVYILDDKKSKDWW
MCQLVDSGKSGLVPAQFIEPVRDKKHTESTASGIIKSIKKNFTKSPSRSRSRSRSKSN
ANASWKDDELQNDVVGSAAGKRSRKSSLSSHKKNSSATKDFPNPKKSRLWVDRSGTFK
VDAEFIGCAKGKIHLHKANGVKIAVAADKLSNEDLAYVEKITGFSLEKFKANDGSSSR
GTDSRDSERERRRRLKEQEEKERDRRLKERELYELKKARELLDEERSRLQEKELPPIK
PPRPTSTTSVPNTTSVPPAESSNNNNSSNKYDWFEFFLNCGVDVSNCQRYTINFDREQ
LTEDMMPDINNSMLRTLGLREGDIVRVMKHLDKKFGRENIASIPTNATGNMFSQPDGS
LNVATSPETSLPQQLLPQTTSPAQTAPSTSAETDDAWTVKPASKSESNLLSKKSEFTG
SMQDLLDLQPLEPKKAAASTPEPNLKDLEPVKTGGTTVPAAPVSSAPVSSAPAPLDPF
KTGGNNILPLSTGFVMMPMITGGDMLPMQRTGGFVVPQTTFGMQSQVTGGILPVQKTG
NGLIPISNTGGAMMPQTTFGAAATVLPLQKTGGGLIPIATTGGAQFPQTSFNVQGQQQ
LPTGSILPVQKTANGLISANTGVSMPTVQRTGGTMIPQTSFGVSQQLTGGAMMTQPQN
TGSAMMPQTSFNAVPQITGGAMMPQTSFNALPQVTGGAMMPLQRTGGALNTFNTGGAM
IPQTSFSSQAQNTGGFRPQSQFGLTLQKTGGIAPLNQNQFTGGAMNTLSTGGVLQQQQ
PQTMNTFNTGGVMQELQMMTTFNTGGAMQQPQMMNTFNTDGIMQQPQMMNTFNTGGAM
QQPQQQALQNQPTGFGFGNGPQQSRQANIFNATASNPFGF"
gene complement(216587..217129)
/gene="LDB7"
/locus_tag="YBL006C"
/gene_synonym="RSC14"
/db_xref="GeneID:852277"
mRNA complement(216587..217129)
/gene="LDB7"
/locus_tag="YBL006C"
/gene_synonym="RSC14"
/product="Ldb7p"
/transcript_id="NM_001178246.1"
/db_xref="GI:296142662"
/db_xref="GeneID:852277"
CDS complement(216587..217129)
/gene="LDB7"
/locus_tag="YBL006C"
/gene_synonym="RSC14"
/note="Component of the RSC chromatin remodeling complex;
interacts with Rsc3p, Rsc30p, Npl6p, and Htl1p to form a
module important for a broad range of RSC functions"
/codon_start=1
/product="Ldb7p"
/protein_id="NP_009547.2"
/db_xref="GI:41629675"
/db_xref="SGD:S000000102"
/db_xref="GeneID:852277"
/translation="MSGSNMGYYDVLAGLSALEKSSQVVFSATELQQLTQQSHATDKG
IEGSENSKAKVSKPKRVAVHGYLGGKVSLADAAQVEYEVGHSLLGSYVPRQQLEALSS
VDFSHHFHRTLECKAALETHDVFLAGAGQLSLPFQSHIESPRNSEAKRKRKVIICKRC
QSRFIGSHRRSQLREHACVD"
gene 217470..220400
/gene="PDR3"
/locus_tag="YBL005W"
/gene_synonym="AMY2; TPE2"
/db_xref="GeneID:852278"
mRNA 217470..220400
/gene="PDR3"
/locus_tag="YBL005W"
/gene_synonym="AMY2; TPE2"
/product="Pdr3p"
/transcript_id="NM_001178245.1"
/db_xref="GI:296142663"
/db_xref="GeneID:852278"
CDS 217470..220400
/gene="PDR3"
/locus_tag="YBL005W"
/gene_synonym="AMY2; TPE2"
/note="Transcriptional activator of the pleiotropic drug
resistance network; regulates expression of ATP-binding
cassette (ABC) transporters through binding to cis-acting
sites known as PDREs (PDR responsive elements);
post-translationally up-regulated in cells lacking a
functional mitochondrial genome; PDR3 has a paralog, PDR1,
that arose from the whole genome duplication; relative
distribution to the nucleus increases upon DNA replication
stress"
/codon_start=1
/product="Pdr3p"
/protein_id="NP_009548.1"
/db_xref="GI:6319466"
/db_xref="SGD:S000000101"
/db_xref="GeneID:852278"
/translation="MKVKKSTRSKVSTACVNCRKRKIKCTGKYPCTNCISYDCTCVFL
KKHLPQKEDSSQSLPTTAVAPPSSHANVEASADVQHLDTAIKLDNQYYFKLMNDLIQT
PVSPSATHAPDTSNNPTNDNNILFKDDSKYQNQLVTYQNILTNLYALPPCDDTQLLID
KTKSQLNNLINSWNPEINYPKLSSFSPRPQRSIETYLLTNKYRNKIHMTRFSFWTDQM
VKSQSPDSFLATTPLVDEVFGLFSPIQAFSLRGIGYLIKKNIENTGSSMLIDTKETIY
LILRLFDLCYEHLIQGCISISNPLENYLQKIKQTPTTTASASLPTSPAPLSNDLVISV
IHQLPQPFIQSITGFTTTQLIENLHDSFSMFRIVTQMYAQHRKRFAEFLNQAFSLPHQ
EKSVLFSSFCSSEYLLSTLCYAYYNVTLYHMLDINTLDYLEILVSLLEIQNEIDERFG
FEKMLEVAVTCSTKMGLSRWEYYVGIDENTAERRRKIWWKIYSLEKRFLTDLGDLSLI
NEHQMNCLLPKDFRDMGFINHKEFLTKIGTSSLSPSSPKLKNLSLSRLIEYGELAIAQ
IVGDFFSETLYNEKFTSLEVSVKPTIIRQKLLEKVFEDIESFRLKLAKIKLHTSRVFQ
VAHCKYPEYPKNDLIEAAKFVSYHKNTWFSILGAVNNLIARLSEDPEVITEQSMKYAN
EMFQEWREINQFLIQVDTDFIVWACLDFYELIFFVMASKFYVEDPHITLEDVINTLKV
FKRITNIISFFNNNLDEKDYDCQTFREFSRSSSLVAISIRIIFLKYCYAEQIDRAEFI
ERLKEVEPGLSDLLREFFDTRSFIYRYMLKSVEKSGFHLIIRKMLESDYKFLYRDKLA
TGNIPDQGNSSQISQLYDSTAPSYNNASASAANSPLKLSSLLNSGEESYTQDASENVP
CNLRHQDRSLQQTKRQHSAPSQISANENNIYNLGTLEEFVSSGDLTDLYHTLWNDNTS
YPFL"
LTR 220895..221036
/note="Ty1 LTR"
/db_xref="SGD:S000006804"
mobile_element 221037..226952
/note="YBLWTy1-1; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YBLWTy1-1"
/db_xref="SGD:S000006808"
LTR 221037..221370
/note="Ty1 LTR"
/db_xref="SGD:S000006805"
gene 221330..226598
/locus_tag="YBL005W-B"
/db_xref="GeneID:852280"
mRNA join(<221330..222634,222636..>226598)
/locus_tag="YBL005W-B"
/transcript_id="NM_001180048.1"
/db_xref="GI:296142665"
/db_xref="GeneID:852280"
CDS join(221330..222634,222636..226598)
/locus_tag="YBL005W-B"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_009549.1"
/db_xref="GI:6319468"
/db_xref="SGD:S000002147"
/db_xref="GeneID:852280"
/translation="MESQQLSQHSPIFHGSACASVTSKEVQTTQDPLDISASKTEECE
KVSTQANSQQPTTPPSSAVPENHHHASPQAAQVPLPQNGPYPQQRMMNTQQANISGWP
VYGHPSLMPYPPYQMSPMYAPPGAQSQFTQYPQYVGTHLNTPSPESGNSFPDSSSAKS
NMTSTNQHVRPPPILTSPNDFLNWVKIYIKFLQNSNLGDIIPTATRKAVRQMTDDELT
FLCHTFQLFAPSQFLPPWVKDILSVDYTDIMKILSKSINKMQSDTQEVNDITTLATLH
YNGSTPADAFEAEVTNILDRLNNNGIPINNKVACQFIMRGLSGEYKFLPYARHRCIHM
TVADLFSDIHSMYEEQQESKRNKSTYRRSPSDEKKDSRTYTNTTKPKSITRNSQKPNN
SQSRTARAHNVSTFNNSPGPDNDLIRGSTTEPIQLKNTHDLHLGQELTESTVNHTNHS
DDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQD
NTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLT
ASYQSFIASNEIQQSNDLNIESDHDFQSDIELYPEQPRNVLSKAVSPTDSTPPSTHTE
DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISDIESTDSGGMHRLDVPLLAP
MSQSNTHESSYASKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKR
IIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTELSD
SFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSL
EPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLL
KMKTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQS
NTVHHYALMTSLSLALDNNYHITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLK
KSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMVLFSKNL
NSNKRIIDKLKMQYDTKIINLGESDEEIQYDILGLEIKYQRGKYMKLGMENSLTEKIP
KLNVPLNPKGRKLSAPGQPGLYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRF
DLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISD
ASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSY
LIQELDKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCY
IETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene 221330..222652
/locus_tag="YBL005W-A"
/db_xref="GeneID:852279"
mRNA <221330..>222652
/locus_tag="YBL005W-A"
/transcript_id="NM_001180047.1"
/db_xref="GI:296142664"
/db_xref="GeneID:852279"
CDS 221330..222652
/locus_tag="YBL005W-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_009550.1"
/db_xref="GI:6319467"
/db_xref="SGD:S000002146"
/db_xref="GeneID:852279"
/translation="MESQQLSQHSPIFHGSACASVTSKEVQTTQDPLDISASKTEECE
KVSTQANSQQPTTPPSSAVPENHHHASPQAAQVPLPQNGPYPQQRMMNTQQANISGWP
VYGHPSLMPYPPYQMSPMYAPPGAQSQFTQYPQYVGTHLNTPSPESGNSFPDSSSAKS
NMTSTNQHVRPPPILTSPNDFLNWVKIYIKFLQNSNLGDIIPTATRKAVRQMTDDELT
FLCHTFQLFAPSQFLPPWVKDILSVDYTDIMKILSKSINKMQSDTQEVNDITTLATLH
YNGSTPADAFEAEVTNILDRLNNNGIPINNKVACQFIMRGLSGEYKFLPYARHRCIHM
TVADLFSDIHSMYEEQQESKRNKSTYRRSPSDEKKDSRTYTNTTKPKSITRNSQKPNN
SQSRTARAHNVSTFNNSPGPDNDLIRGSTTEPIQLKNTHDLHLRPGTY"
LTR 226621..226952
/note="Ty1 LTR"
/db_xref="SGD:S000006806"
gene 227075..227156
/locus_tag="tS(AGA)B"
/db_xref="GeneID:852281"
tRNA 227075..227156
/locus_tag="tS(AGA)B"
/product="tRNA-Ser"
/note="Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006720"
/db_xref="GeneID:852281"
gene 227636..235117
/gene="UTP20"
/locus_tag="YBL004W"
/db_xref="GeneID:852282"
mRNA 227636..235117
/gene="UTP20"
/locus_tag="YBL004W"
/product="Utp20p"
/transcript_id="NM_001178244.1"
/db_xref="GI:296142666"
/db_xref="GeneID:852282"
CDS 227636..235117
/gene="UTP20"
/locus_tag="YBL004W"
/note="Component of the small-subunit (SSU) processome,
which is involved in the biogenesis of the 18S rRNA"
/codon_start=1
/product="Utp20p"
/protein_id="NP_009551.2"
/db_xref="GI:14270688"
/db_xref="SGD:S000000100"
/db_xref="GeneID:852282"
/translation="MAKQRQTTKSSKRYRYSSFKARIDDLKIEPARNLEKRVHDYVES
SHFLASFDQWKEINLSAKFTEFAAEIEHDVQTLPQILYHDKKIFNSLVSFINFHDEFS
LQPLLDLLAQFCHDLGPDFLKFYEEAIKTLINLLDAAIEFESSNVFEWGFNCLAYIFK
YLSKFLVKKLVLTCDLLIPLLSHSKEYLSRFSAEALSFLVRKCPVSNLREFVRSVFEK
LEGDDEQTNLYEGLLILFTESMTSTQETLHSKAKAIMSVLLHEALTKSSPERSVSLLS
DIWMNISKYASIESLLPVYEVMYQDFNDSLDATNIDRILKVLTTIVFSESGRKIPDWN
KITILIERIMSQSENCASLSQDKVAFLFALFIRNSDVKTLTLFHQKLFNYALTNISDC
FLEFFQFALRLSYERVFSFNGLKFLQLFLKKNWQSQGKKIALFFLEVDDKPELQKVRE
VNFPEEFILSIRDFFVTAEINDSNDLFEIYWRAIIFKYSKLQNTEIIIPLLERIFSTF
ASPDNFTKDMVGTLLKIYRKEDDASGNNLLKTILDNYENYKESLNFLRGWNKLVSNLH
PSESLKGLMSHYPSLLLSLTDNFMLPDGKIRYETLELMKTLMILQGMQVPDLLSSCMV
IEEIPLTLQNARDLTIRIKNVGAEFGKTKTDKLVSSFFLKYLFGLLTVRFSPVWTGVF
DTLPNVYTKDEALVWKLVLSFIKLPDENQNLDYYQPLLEDGANKVLWDSSVVRLRDTI
DTFSHIWSKYSTQNTSIISTTIERRGNTTYPILIRNQALKVMLSIPQVAENHFVDIAP
FVYNDFKTYKDEEDMENERVITGSWTEVDRNVFLKTLSKFKNIKNVYSATELHDHLMV
LLGSRNTDVQKLALDALLAYKNPTLNKYRDNLKNLLDDTLFKDEITTFLTENGSQSIK
AEDEKVVMPYVLRIFFGRAQVPPTSGQKRSRKIAVISVLPNFKKPYINDFLSLASERL
DYNYFFGNSHQINSSKATLKTIRRMTGFVNIVNSTLSVLRTNFPLHTNSVLQPLIYSI
AMAYYVLDTESTEEVHLRKMASNLRQQGLKCLSSVFEFVGNTFDWSTSMEDIYAVVVK
PRISHFSDENLQQPSSLLRLFLYWAHNPSLYQFLYYDEFATATALMDTISNQHVKEAV
IGPIIEAADSIIRNPVNDDHYVDLVTLICTSCLKILPSLYVKLSDSNSISTFLNLLVS
ITEMGFIQDDHVRSRLISSLISILKGKLKKLQENDTQKILKILKLIVFNYNCSWSDIE
ELYTTISSLFKTFDERNLRVSLTELFIELGRKVPELESISKLVADLNSYSSSRMHEYD
FPRILSTFKGLIEDGYKSYSELEWLPLLFTFLHFINNKEELALRTNASHAIMKFIDFI
NEKPNLNEASKSISMLKDILLPNIRIGLRDSLEEVQSEYVSVLSYMVKNTKYFTDFED
MAILLYNGDEEADFFTNVNHIQLHRRQRAIKRLGEHAHQLKDNSISHYLIPMIEHYVF
SDDERYRNIGNETQIAIGGLAQHMSWNQYKALLRRYISMLKTKPNQMKQAVQLIVQLS
VPLRETLRIVRDGAESKLTLSKFPSNLDEPSNFIKQELYPTLSKILGTRDDETIIERM
PIAEALVNIVLGLTNDDITNFLPSILTNICQVLRSKSEELRDAVRVTLGKISIILGAE
YLVFVIKELMATLKRGSQIHVLSYTVHYILKSMHGVLKHSDLDTSSSMIVKIIMENIF
GFAGEEKDSENYHTKVKEIKSNKSYDAGEILASNISLTEFGTLLSPVKALLMVRINLR
NQNKLSELLRRYLLGLNHNSDSESESILKFCHQLFQESEMSNSPQIPKKKVKDQVDEK
EDFFLVNLESKSYTINSNSLLLNSTLQKFALDLLRNVITRHRSFLTVSHLEGFIPFLR
DSLLSENEGVVISTLRILITLIRLDFSDESSEIFKNCARKVLNIIKVSPSTSSELCQM
GLKFLSAFIRHTDSTLKDTALSYVLGRVLPDLNEPSRQGLAFNFLKALVSKHIMLPEL
YDIADTTREIMVTNHSKEIRDVSRSVYYQFLMEYDQSKGRLEKQFKFMVDNLQYPTES
GRQSVMELINLIITKANPALLSKLSSSFFLALVNVSFNDDAPRCREMASVLISTMLPK
LENKDLEIVEKYIAAWLKQVDNASFLNLGLRTYKVYLKSIGFEHTIELDELAIKRIRY
ILSDTSVGSEHQWDLVYSALNTFSSYMEATESVYKHGFKDIWDGIITCLLYPHSWVRQ
SAANLVHQLIANKDKLEISLTNLEIQTIATRILHQLGAPSIPENLANVSIKTLVNISI
LWKEQRTPFIMDVSKQTGEDLKYTTAIDYMVTRIGGIIRSDEHRMDSFMSKKACIQLL
ALLVQVLDEDEVIAEGEKILLPLYGYLETYYSRAVDEEQEELRTLSNECLKILEDKLQ
VSDFTKIYTAVKQTVLERRKERRSKRAILAVNAPQISADKKLRKHARSREKRKHEKDE
NGYYQRRNKRKRA"
gene complement(235394..235792)
/gene="HTA2"
/locus_tag="YBL003C"
/gene_synonym="H2A2"
/db_xref="GeneID:852283"
mRNA complement(235394..235792)
/gene="HTA2"
/locus_tag="YBL003C"
/gene_synonym="H2A2"
/product="Hta2p"
/transcript_id="NM_001178243.1"
/db_xref="GI:296142667"
/db_xref="GeneID:852283"
CDS complement(235394..235792)
/gene="HTA2"
/locus_tag="YBL003C"
/gene_synonym="H2A2"
/note="Histone H2A, core histone protein required for
chromatin assembly and chromosome function; one of two
nearly identical (see also HTA1) subtypes; DNA
damage-dependent phosphorylation by Mec1p facilitates DNA
repair; acetylated by Nat4p"
/codon_start=1
/product="Hta2p"
/protein_id="NP_009552.1"
/db_xref="GI:6319470"
/db_xref="SGD:S000000099"
/db_xref="GeneID:852283"
/translation="MSGGKGGKAGSAAKASQSRSAKAGLTFPVGRVHRLLRRGNYAQR
IGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNV
TIAQGGVLPNIHQNLLPKKSAKTAKASQEL"
gene 236492..236887
/gene="HTB2"
/locus_tag="YBL002W"
/db_xref="GeneID:852284"
mRNA 236492..236887
/gene="HTB2"
/locus_tag="YBL002W"
/product="Htb2p"
/transcript_id="NM_001178242.1"
/db_xref="GI:296142668"
/db_xref="GeneID:852284"
CDS 236492..236887
/gene="HTB2"
/locus_tag="YBL002W"
/note="Histone H2B, core histone protein required for
chromatin assembly and chromosome function; nearly
identical to HTB1; Rad6p-Bre1p-Lge1p mediated
ubiquitination regulates transcriptional activation,
meiotic DSB formation and H3 methylation"
/codon_start=1
/product="Htb2p"
/protein_id="NP_009553.1"
/db_xref="GI:6319471"
/db_xref="SGD:S000000098"
/db_xref="GeneID:852284"
/translation="MSSAAEKKPASKAPAEKKPAAKKTSTSVDGKKRSKVRKETYSSY
IYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATEASKLAAYNKKSTISAREIQTAV
RLILPGELAKHAVSEGTRAVTKYSSSTQA"
gene complement(237153..237467)
/gene="ECM15"
/locus_tag="YBL001C"
/db_xref="GeneID:852285"
mRNA complement(237153..237467)
/gene="ECM15"
/locus_tag="YBL001C"
/product="Ecm15p"
/transcript_id="NM_001178241.1"
/db_xref="GI:296142669"
/db_xref="GeneID:852285"
CDS complement(237153..237467)
/gene="ECM15"
/locus_tag="YBL001C"
/note="Non-essential hypothetical protein, likely exists
as tetramer, may be regulated by the binding of
small-molecule ligands (possibly sulfate ions), may have a
role in yeast cell-wall biogenesis"
/codon_start=1
/product="Ecm15p"
/protein_id="NP_009554.1"
/db_xref="GI:6319472"
/db_xref="SGD:S000000097"
/db_xref="GeneID:852285"
/translation="MPKIFCLADVCMVPIGTDSASISDFVALIEKKIRESPLKSTLHS
AGTTIEGPWDDVMGLIGEIHEYGHEKGYVRVHTDIRVGTRTDKHQTAQDKIDVVLKKI
SQ"
rep_origin 237684..237918
/note="ARS208;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118346"
centromere 238207..238323
/note="CEN2; Chromosome II centromere"
/db_xref="SGD:S000006464"
centromere 238207..238216
/note="CEN2_CDEI of CEN2"
centromere 238217..238298
/note="CEN2_CDEII of CEN2"
centromere 238299..238323
/note="CEN2_CDEIII of CEN2"
gene complement(238941..241283)
/gene="NTH2"
/locus_tag="YBR001C"
/db_xref="GeneID:852286"
mRNA complement(238941..241283)
/gene="NTH2"
/locus_tag="YBR001C"
/product="alpha,alpha-trehalase NTH2"
/transcript_id="NM_001178349.1"
/db_xref="GI:296142670"
/db_xref="GeneID:852286"
CDS complement(238941..241283)
/gene="NTH2"
/locus_tag="YBR001C"
/EC_number="3.2.1.28"
/note="Putative neutral trehalase, required for
thermotolerance and may mediate resistance to other
cellular stresses"
/codon_start=1
/product="alpha,alpha-trehalase NTH2"
/protein_id="NP_009555.1"
/db_xref="GI:6319473"
/db_xref="SGD:S000000205"
/db_xref="GeneID:852286"
/translation="MVDFLPKVTEINPPSEGNDGEDNIKPLSSGSEQRPLKEEGQQGG
RRHHRRLSSMHEYFDPFSNAEVYYGPITDPRKQSKIHRLNRTRTMSVFNKVSDFKNGM
KDYTLKRRGSEDDSFLSSQGNRRFYIDNVDLALDELLASEDTDKNHQITIEDTGPKVI
KVGTANSNGFKHVNVRGTYMLSNLLQELTIAKSFGRHQIFLDEARINENPVDRLSRLI
TTQFWTSLTRRVDLYNIAEIARDSKIDTPGAKNPRIYVPYNCPEQYEFYIQASQMNPS
LKLEVEYLPKDITAEYVKSLNDTPGLLALAMEEHVNPSTGERSLVGYPYAVPGGRFNE
LYGWDSYLMALGLIESNKVDVARGMVEHFIFEIDHYSKILNANRSYYLCRSQPPFLTD
MALLVFEKIGGKNNPNAIQLLKRAFRAAIKEYKEVWMSSPRLDSLTGLSCYHSDGIGI
PPETEPDHFDTILLPYAEKYNVTLEKLRYLYNEGMIKEPKLDAFFLHDRAVRESGHDT
TYRFEGVCAYLATIDLNSLLYKYEKDIAFVIKEYFGNEYKDENDGTVTDSEHWEELAE
LRKTRINKYMWDEDSGFFFYYNTKLKCRTSYESATTFWSLWAGLATEEQAKITVEKAL
PQLEMLGGLVACTEKSRGPISIDRPIRQWDYPFGWAPHQILAWKGLSAYGYQQVATRL
AYRWLYMITKSFVDYNGMVVEKYDVTRGTDPHRVDAEYGNQGADFKGVATEGFGWVNT
SYLLGLKYMNNHARRALAACSPPLPFFNSLKPSEKKLYYL"
gene complement(241708..242568)
/gene="RER2"
/locus_tag="YBR002C"
/db_xref="GeneID:852287"
mRNA complement(241708..242568)
/gene="RER2"
/locus_tag="YBR002C"
/product="Rer2p"
/transcript_id="NM_001178350.1"
/db_xref="GI:296142671"
/db_xref="GeneID:852287"
CDS complement(241708..242568)
/gene="RER2"
/locus_tag="YBR002C"
/EC_number="2.5.1.-"
/note="Cis-prenyltransferase involved in dolichol
synthesis; participates in endoplasmic reticulum (ER)
protein sorting"
/codon_start=1
/product="Rer2p"
/protein_id="NP_009556.1"
/db_xref="GI:6319474"
/db_xref="SGD:S000000206"
/db_xref="GeneID:852287"
/translation="METDSGIPGHSFVLKWTKNIFSRTLRASNCVPRHVGFIMDGNRR
FARKKEMDVKEGHEAGFVSMSRILELCYEAGVDTATVFAFSIENFKRSSREVESLMTL
ARERIRQITERGELACKYGVRIKIIGDLSLLDKSLLEDVRVAVETTKNNKRATLNICF
PYTGREEILHAMKETIVQHKKGAAIDESTLESHLYTAGVPPLDLLIRTSGVSRLSDFL
IWQASSKGVRIELLDCLWPEFGPIRMAWILLKFSFHKSFLNKEYRLEEGDYDEETNGD
PIDLKEKKLN"
gene 242809..244230
/gene="COQ1"
/locus_tag="YBR003W"
/db_xref="GeneID:852288"
mRNA 242809..244230
/gene="COQ1"
/locus_tag="YBR003W"
/product="trans-hexaprenyltranstransferase"
/transcript_id="NM_001178351.1"
/db_xref="GI:296142672"
/db_xref="GeneID:852288"
CDS 242809..244230
/gene="COQ1"
/locus_tag="YBR003W"
/EC_number="2.5.1.-"
/note="Hexaprenyl pyrophosphate synthetase, catalyzes the
first step in ubiquinone (coenzyme Q) biosynthesis"
/codon_start=1
/product="trans-hexaprenyltranstransferase"
/protein_id="NP_009557.1"
/db_xref="GI:6319475"
/db_xref="SGD:S000000207"
/db_xref="GeneID:852288"
/translation="MFQRSGAAHHIKLISSRRCRFKSSFAVALNAASKLVTPKILWNN
PISLVSKEMNTLAKNIVALIGSGHPVLNKVTSYYFETEGKKVRPLLVLLLSRALSEIP
MTERNHLKIDKSDVPEDPIYSKPSQNQLFQRPASSISPLHILHGIKPLNPLTKGPEPL
PEETFDKQRGILPKQRRLAEIVEMIHTASLLHDDVIDHSDTRRGRPSGNAAFTNKMAV
LAGDFLLGRATVSISRLHNPEVVELMSNSIANLVEGEFMQLKNTSIDADIDTIENGHK
LLPVPSKKLEVKEHDFRVPSRQQGLQLSHDQIIETAFEYYIHKTYLKTAALISKSCRC
AAILSGASPAVIDECYDFGRNLGICFQLVDDMLDFTVSGKDLGKPSGADLKLGIATAP
VLFAWKEDPSLGPLISRNFSERGDVEKTIDSVRLHNGIAKTKILAEEYRDKALQNLRD
SLPESDARSALEFLTNSILTRRK"
gene complement(244366..245667)
/gene="GPI18"
/locus_tag="YBR004C"
/db_xref="GeneID:852289"
mRNA complement(244366..245667)
/gene="GPI18"
/locus_tag="YBR004C"
/product="Gpi18p"
/transcript_id="NM_001178352.2"
/db_xref="GI:330443420"
/db_xref="GeneID:852289"
CDS complement(244366..245667)
/gene="GPI18"
/locus_tag="YBR004C"
/EC_number="2.4.1.-"
/note="Functional ortholog of human PIG-V, which is a
mannosyltransferase that transfers the second mannose in
glycosylphosphatidylinositol biosynthesis; the authentic,
non-tagged protein was localized to mitochondria"
/codon_start=1
/product="Gpi18p"
/protein_id="NP_009558.2"
/db_xref="GI:330443421"
/db_xref="SGD:S000000208"
/db_xref="GeneID:852289"
/translation="MIVGLTLYFVLFRSIQYLLVFLTPIRQFDTSTSLLLNELCSSPS
EINSYWNKYFWNKLLSWDSVFFIKNITSKNGKPQFEHEYAFSQLWTFFVRLFIKSNND
SIYHALRVGVAIENVLFYLSGIVLYFLTKKIFSQNIRQSQFARTIAKKTSLLFFLTSA
AGFLTSIYSEPLSFFFAFVGIWSRECSISVPVLGQFDISWRYWFPYSFISMACFTLAS
LNRSNCVLLGIYFIFDLIELTKNRKFVKAICFPLLSGSLMFSALLYQQYYLPYKTFCP
QRGEWCKSQLFSSIFITKTSLYSYIQSHYWGVGLLKYWTPNNIPNFLFAVPNIIILIY
SSIYFSKIYPSYNLKALVWITRALVVIVCFFAHVQILNRIASFLPLHLWYLADRLVKT
SDPKKMENPKGDDKIVKFYIYWLAFWIPLQTILFAAFLPPA"
gene 245906..246547
/gene="RCR1"
/locus_tag="YBR005W"
/gene_synonym="SSH6"
/db_xref="GeneID:852290"
mRNA 245906..246547
/gene="RCR1"
/locus_tag="YBR005W"
/gene_synonym="SSH6"
/product="Rcr1p"
/transcript_id="NM_001178353.1"
/db_xref="GI:296142674"
/db_xref="GeneID:852290"
CDS 245906..246547
/gene="RCR1"
/locus_tag="YBR005W"
/gene_synonym="SSH6"
/note="Protein of the ER membrane involved in cell wall
chitin deposition; may function in the endosomal-vacuolar
trafficking pathway, helping determine whether plasma
membrane proteins are degraded or routed to the plasma
membrane"
/codon_start=1
/product="Rcr1p"
/protein_id="NP_009559.1"
/db_xref="GI:6319477"
/db_xref="SGD:S000000209"
/db_xref="GeneID:852290"
/translation="MGLISYENEAINEVKKADNHHVSKFVTSYYGPSSSSWQSGIWIL
FVLFVAAVILIILFTFVANRRRRRMGRAPIRGTAWLTPPSYRQSQQQYTGTVQQRTDD
YVPEYTETANEHDLGYYDQRGEFHPNDKAAYVAPPPLVQECSSESVNSLERPPAAVVH
QANSLDTDYGLTRPSNGRVPAVSDTVEQLERLPGGTTTQEINPPERAKVNARS"
gene 247010..248503
/gene="UGA2"
/locus_tag="YBR006W"
/gene_synonym="UGA5"
/db_xref="GeneID:852291"
mRNA 247010..248503
/gene="UGA2"
/locus_tag="YBR006W"
/gene_synonym="UGA5"
/product="succinate-semialdehyde dehydrogenase
(NAD(P)(+))"
/transcript_id="NM_001178354.1"
/db_xref="GI:296142675"
/db_xref="GeneID:852291"
CDS 247010..248503
/gene="UGA2"
/locus_tag="YBR006W"
/gene_synonym="UGA5"
/EC_number="1.2.1.16"
/note="Succinate semialdehyde dehydrogenase involved in
the utilization of gamma-aminobutyrate (GABA) as a
nitrogen source; part of the 4-aminobutyrate and glutamate
degradation pathways; localized to the cytoplasm"
/codon_start=1
/product="succinate-semialdehyde dehydrogenase
(NAD(P)(+))"
/protein_id="NP_009560.1"
/db_xref="GI:6319478"
/db_xref="SGD:S000000210"
/db_xref="GeneID:852291"
/translation="MTLSKYSKPTLNDPNLFRESGYIDGKWVKGTDEVFEVVDPASGE
IIARVPEQPVSVVEEAIDVAYETFKTYKNTTPRERAKWLRNMYNLMLENLDDLATIIT
LENGKALGEAKGEIKYAASYFEWYAEEAPRLYGATIQPLNPHNRVFTIRQPVGVCGII
CPWNFPSAMITRKAAAALAVGCTVVIKPDSQTPLSALAMAYLAEKAGFPKGSFNVILS
HANTPKLGKTLCESPKVKKVTFTGSTNVGKILMKQSSSTLKKLSFELGGNAPFIVFED
ADLDQALEQAMACKFRGLGQTCVCANRLYVHSSIIDKFAKLLAERVKKFVIGHGLDPK
TTHGCVINSSAIEKVERHKQDAIDKGAKVVLEGGRLTELGPNFYAPVILSHVPSTAIV
SKEETFGPLCPIFSFDTMEEVVGYANDTEFGLAAYVFSKNVNTLYTVSEALETGMVSC
NTGVFSDCSIPFGGVKESGFGREGSLYGIEDYTVLKTITIGNLPNSI"
gene complement(248806..251016)
/gene="DSF2"
/locus_tag="YBR007C"
/db_xref="GeneID:852292"
mRNA complement(248806..251016)
/gene="DSF2"
/locus_tag="YBR007C"
/product="Dsf2p"
/transcript_id="NM_001178355.2"
/db_xref="GI:330443422"
/db_xref="GeneID:852292"
CDS complement(248806..251016)
/gene="DSF2"
/locus_tag="YBR007C"
/note="Deletion suppressor of mpt5 mutation; relocalizes
from bud neck to cytoplasm upon DNA replication stress"
/codon_start=1
/product="Dsf2p"
/protein_id="NP_009561.2"
/db_xref="GI:330443423"
/db_xref="SGD:S000000211"
/db_xref="GeneID:852292"
/translation="MNQNLKNTSWADRIGSDDQERKANSSEVSQSPPPNNSFESSMDS
QFSYAHSNKSSISFESIQTTERLLDKLDLSLEDELILQEALLEEENASRNSQLSQTSG
PTLCMPASEFPSLRYRTNPSPTYIQARDRSLIIDNLKEKDSTLRGKYSSGKVERHLPV
KSRYSYIVEEDYDSETFSGMKPQMNRNEKDYKYPNLENGNRSTNSPNPFNFEKYRIEN
TRLHHLYPTLISDNNTSVDNNANSKNNRTTSNNINTSTKTDRISEKQSCPNEFTTTQK
SNCLYRNGSSTSTNTSFSEVGQLSKPKTQSSFESESSSFSKLKLTKSDTTPIKPSPKR
SNSSTSTITKTNTMTNDISLPPTPPYKAHKKKTSLNSLKKLFKSPRTRAKNKKDLESE
GSSPIRSATNSLDFSGENIQLPSTSSTINNSSPHLARYIFPPNPVFHFKTASTPQSST
DKKKNSKARPNRTHLRTFSDFHTTEKDSKIGELSALTEQSNKPYHPKVRRRTLSLDGM
LPNNSTQCMDSFSHKKEGSNATSKCGKLKFHPEPYDNDESSHIGQAITMRHQGKLEES
AQRLKKACACGNKTAFLLYGLALRHGCGVDKNLKLSLGYLMAATDIKSFAAEVLDLDI
NPLNFASMDDIPDIAPEPTAPALYECGMAYLKGLGMDHPDERKGLKFLEKAALLGHVD
SMCLSGTIWSKTSNVKKRDLARAAAWFRIADKKGANLLGSDWIYKEKYMKQGPK"
gene complement(252563..254209)
/gene="FLR1"
/locus_tag="YBR008C"
/db_xref="GeneID:852293"
mRNA complement(252563..254209)
/gene="FLR1"
/locus_tag="YBR008C"
/product="Flr1p"
/transcript_id="NM_001178356.1"
/db_xref="GI:296142677"
/db_xref="GeneID:852293"
CDS complement(252563..254209)
/gene="FLR1"
/locus_tag="YBR008C"
/note="Plasma membrane transporter of the major
facilitator superfamily; member of the 12-spanner
drug:H(+) antiporter DHA1 family; involved in efflux of
fluconazole, diazaborine, benomyl, methotrexate, and other
drugs; expression induced in cells treated with the
mycotoxin patulin; relocalizes from nucleus to plasma
membrane upon DNA replication stress"
/codon_start=1
/product="Flr1p"
/protein_id="NP_009562.1"
/db_xref="GI:6319480"
/db_xref="SGD:S000000212"
/db_xref="GeneID:852293"
/translation="MVYTSTYRHTIVVDLLEYLGIVSNLETLQSAREDETRKPENTDK
KECKPDYDIECGPNRSCSESSTDSDSSGSQIEKNDPFRVDWNGPSDPENPQNWPLLKK
SLVVFQIMLLTCVTYMGSSIYTPGQEYIQEEFHVGHVVATLNLSLYVLGYGLGPIIFS
PLSETARYGRLNLYMVTLFFFMIFQVGCATVHNIGGLIVMRFISGILCSPSLATGGGT
VADIISPEMVPLVLGMWSAGAVAAPVLAPLLGAAMVDAKNWRFIFWLLMWLSAATFIL
LAFFFPETQHHNILYRRALKLRKETGDDRYYTEQDKLDREVDARTFLINTLYRPLKMI
IKEPAILAFDLYIAVAYGCFYLFFEAFPIVFVGIYHFSLVEVGLAYMGFCVGCVLAYG
LFGILNMRIIVPRFRNGTFTPEAFLIVAMCVCWCLPLSLFLFGWTARVHWILPVISEV
FFVLAVFNIFQATFAYLATCYPKYVASVFAGNGFCRASFACAFPLFGRAMYDNLATKN
YPVAWGSSLVGFLTLGLAIIPFILYKYGPSLRTRSSYTEE"
rep_origin 254206..255370
/note="ARS209;
Autonomously Replicating Sequence, originally referred to
as H4 ARS"
/db_xref="SGD:S000114517"
gene complement(255373..255684)
/gene="HHF1"
/locus_tag="YBR009C"
/db_xref="GeneID:852294"
mRNA complement(255373..255684)
/gene="HHF1"
/locus_tag="YBR009C"
/product="Hhf1p"
/transcript_id="NM_001178357.1"
/db_xref="GI:296142678"
/db_xref="GeneID:852294"
CDS complement(255373..255684)
/gene="HHF1"
/locus_tag="YBR009C"
/note="Histone H4, core histone protein required for
chromatin assembly and chromosome function; one of two
identical histone proteins (see also HHF2); contributes to
telomeric silencing; N-terminal domain involved in
maintaining genomic integrity"
/codon_start=1
/product="Hhf1p"
/protein_id="NP_009563.1"
/db_xref="GI:6319481"
/db_xref="SGD:S000000213"
/db_xref="GeneID:852294"
/translation="MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGV
KRISGLIYEEVRAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFG
G"
gene 256331..256741
/gene="HHT1"
/locus_tag="YBR010W"
/gene_synonym="BUR5; SIN2"
/db_xref="GeneID:852295"
mRNA 256331..256741
/gene="HHT1"
/locus_tag="YBR010W"
/gene_synonym="BUR5; SIN2"
/product="Hht1p"
/transcript_id="NM_001178358.1"
/db_xref="GI:296142679"
/db_xref="GeneID:852295"
CDS 256331..256741
/gene="HHT1"
/locus_tag="YBR010W"
/gene_synonym="BUR5; SIN2"
/note="Histone H3, core histone protein required for
chromatin assembly, part of heterochromatin-mediated
telomeric and HM silencing; one of two identical histone
H3 proteins (see HHT2); regulated by acetylation,
methylation, and phosphorylation"
/codon_start=1
/product="Hht1p"
/protein_id="NP_009564.1"
/db_xref="GI:6319482"
/db_xref="SGD:S000000214"
/db_xref="GeneID:852295"
/translation="MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKP
GTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLV
SLFEDTNLAAIHAKRVTIQKKDIKLARRLRGERS"
gene complement(257112..257975)
/gene="IPP1"
/locus_tag="YBR011C"
/gene_synonym="PPA1"
/db_xref="GeneID:852296"
mRNA complement(257112..257975)
/gene="IPP1"
/locus_tag="YBR011C"
/gene_synonym="PPA1"
/product="Ipp1p"
/transcript_id="NM_001178359.1"
/db_xref="GI:296142680"
/db_xref="GeneID:852296"
CDS complement(257112..257975)
/gene="IPP1"
/locus_tag="YBR011C"
/gene_synonym="PPA1"
/EC_number="3.6.1.1"
/note="Cytoplasmic inorganic pyrophosphatase (PPase),
homodimer that catalyzes the rapid exchange of oxygens
from Pi with water, highly expressed and essential for
viability, active-site residues show identity to those
from E. coli PPase"
/codon_start=1
/product="Ipp1p"
/protein_id="NP_009565.1"
/db_xref="GI:6319483"
/db_xref="SGD:S000000215"
/db_xref="GeneID:852296"
/translation="MTYTTRQIGAKNTLEYKVYIEKDGKPVSAFHDIPLYADKENNIF
NMVVEIPRWTNAKLEITKEETLNPIIQDTKKGKLRFVRNCFPHHGYIHNYGAFPQTWE
DPNVSHPETKAVGDNDPIDVLEIGETIAYTGQVKQVKALGIMALLDEGETDWKVIAID
INDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAFSGEAKNKKYALD
IIKETHDSWKQLIAGKSSDSKGIDLTNVTLPDTPTYSKAASDAIPPASPKADAPIDKS
IDKWFFISGSV"
LTR complement(258670..258976)
/note="Ty1 LTR"
/db_xref="SGD:S000006810"
mobile_element 259578..265494
/note="YBRWTy1-2; Ty1 element, LTR retrotransposon of the
Copia (Pseudoviridae) group; contains co-transcribed genes
TYA Gag and TYB Pol, encoding proteins involved in
structure and function of virus-like particles, flanked by
two direct repeats"
/mobile_element_type="retrotransposon:YBRWTy1-2"
/db_xref="SGD:S000006821"
LTR 259578..259909
/note="Ty1 LTR"
/db_xref="SGD:S000006815"
gene 259869..265140
/locus_tag="YBR012W-B"
/db_xref="GeneID:852299"
mRNA join(<259869..261173,261175..>265140)
/locus_tag="YBR012W-B"
/transcript_id="NM_001180056.1"
/db_xref="GI:296142682"
/db_xref="GeneID:852299"
CDS join(259869..261173,261175..265140)
/locus_tag="YBR012W-B"
/EC_number="2.7.7.49"
/EC_number="3.4.23.-"
/EC_number="3.1.26.4"
/EC_number="2.7.7.7"
/ribosomal_slippage
/note="Retrotransposon TYA Gag and TYB Pol genes;
transcribed/translated as one unit; polyprotein is
processed to make a nucleocapsid-like protein (Gag),
reverse transcriptase (RT), protease (PR), and integrase
(IN); similar to retroviral genes"
/codon_start=1
/product="gag-pol fusion protein"
/protein_id="NP_009567.1"
/db_xref="GI:6319486"
/db_xref="SGD:S000002155"
/db_xref="GeneID:852299"
/translation="MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRPITDDELT
FLYNAFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHS
DDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQD
NTKTSLKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWV
SKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNE
SDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKS
APSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSE
YTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFS
AIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGI
PGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKDSRLDQFNYDALTFDEDLNRLT
ASYQSFIASNEIQQSNDLNIESDHDFQSDIELYPEQPRNVLSKAVSPTDSTPPSTHTE
DSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISDIESTDSGGMHRLDVPLLAP
MSQSNTHESSYASKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKR
IIHRFTSDRILPSSESNSLHHVVPIKTSDTCFKENTEESIIADLPLPDLPPEPPTELS
DSFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRS
LEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQL
LKMKTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQ
SNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRL
KKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKD
LNSNKRIIAKLKMQYDTKIINLGESDDEIQHDILGLEIKYQRGKYMKLGMENSLTEKI
PKLNVPLNPNGRKLGAPGQPGLYINQQELELEEDDYKMKVHEMQKLIGLASYVGYKFR
FDLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVIS
DASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLS
YLIQELDKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVC
YIETKKNIADVMTKPLPIKTFKLLTNKWIH"
gene 259869..261191
/locus_tag="YBR012W-A"
/db_xref="GeneID:852298"
mRNA <259869..>261191
/locus_tag="YBR012W-A"
/transcript_id="NM_001180055.1"
/db_xref="GI:296142681"
/db_xref="GeneID:852298"
CDS 259869..261191
/locus_tag="YBR012W-A"
/note="Retrotransposon TYA Gag gene co-transcribed with
TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is
a nucleocapsid protein that is the structural constituent
of virus-like particles (VLPs); similar to retroviral Gag"
/codon_start=1
/product="gag protein"
/protein_id="NP_009568.1"
/db_xref="GI:6319485"
/db_xref="SGD:S000002154"
/db_xref="GeneID:852298"
/translation="MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYD
KASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWS
FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRPITDDELT
FLYNAFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY"
LTR 265163..265494
/note="Ty1 LTR"
/db_xref="SGD:S000006816"
gene complement(265492..265881)
/locus_tag="YBR013C"
/db_xref="GeneID:852300"
mRNA complement(265492..265881)
/locus_tag="YBR013C"
/product="hypothetical protein"
/transcript_id="NM_001178361.1"
/db_xref="GI:296142683"
/db_xref="GeneID:852300"
CDS complement(265492..265881)
/locus_tag="YBR013C"
/note="hypothetical protein, haploid deletion mutant
exhibits synthetic phenotype with alpha-synuclein"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009569.1"
/db_xref="GI:6319487"
/db_xref="SGD:S000000217"
/db_xref="GeneID:852300"
/translation="MIYPLFRICILGAFLLGSYACLENSTQKGIEGVTLSHNSVQINN
TLAKSAPFCESDALSMNYSTENMLSNNACDYTKNSSYPYIITIITKAFDNALENSLNL
QANRKLYHRVGTCIQNIFYQLLLTVNY"
LTR complement(266178..266256)
/note="Ty1 LTR"
/db_xref="SGD:S000006811"
gene 266378..266450
/locus_tag="tT(AGU)B"
/db_xref="GeneID:852301"
tRNA 266378..266450
/locus_tag="tT(AGU)B"
/product="tRNA-Thr"
/note="Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006737"
/db_xref="GeneID:852301"
gene complement(266725..267336)
/gene="GRX7"
/locus_tag="YBR014C"
/db_xref="GeneID:852302"
mRNA complement(266725..267336)
/gene="GRX7"
/locus_tag="YBR014C"
/product="glutathione-disulfide reductase GRX7"
/transcript_id="NM_001178362.1"
/db_xref="GI:296142684"
/db_xref="GeneID:852302"
CDS complement(266725..267336)
/gene="GRX7"
/locus_tag="YBR014C"
/note="Cis-golgi localized monothiol glutaredoxin; more
similar in activity to dithiol than other monothiol
glutaredoxins; involved in the oxidative stress response;
does not bind metal ions; functional overlap with GRX6"
/codon_start=1
/product="glutathione-disulfide reductase GRX7"
/protein_id="NP_009570.1"
/db_xref="GI:6319488"
/db_xref="SGD:S000000218"
/db_xref="GeneID:852302"
/translation="MAIVINKRNVRVLVITNLLLIVVFFVLRNSNASVNESITTHHPD
SLVTFDNSGNAPGTHQSVHDTVNTQDKEAEEVDKNSGDAEFDAAAEYNKIMEQSPMIV
FSKTGCPYSKKLKALLTNSYTFSPSYYVVELDRHEHTKELQDQIEKVTGRRTVPNVII
GGTSRGGYTEIAELHKNDELLDSFKKWSDGAFTVKANSQSESA"
gene complement(267710..269503)
/gene="MNN2"
/locus_tag="YBR015C"
/gene_synonym="CRV4; LDB8; TTP1"
/db_xref="GeneID:852303"
mRNA complement(267710..269503)
/gene="MNN2"
/locus_tag="YBR015C"
/gene_synonym="CRV4; LDB8; TTP1"
/product="Mnn2p"
/transcript_id="NM_001178363.1"
/db_xref="GI:296142685"
/db_xref="GeneID:852303"
CDS complement(267710..269503)
/gene="MNN2"
/locus_tag="YBR015C"
/gene_synonym="CRV4; LDB8; TTP1"
/note="Alpha-1,2-mannosyltransferase, responsible for
addition of the first alpha-1,2-linked mannose to form the
branches on the mannan backbone of oligosaccharides,
localizes to an early Golgi compartment"
/codon_start=1
/product="Mnn2p"
/protein_id="NP_009571.1"
/db_xref="GI:6319489"
/db_xref="SGD:S000000219"
/db_xref="GeneID:852303"
/translation="MLLTKRFSKLFKLTFIVLILCGLFVITNKYMDENTSVKEYKEYL
DRYVQSYSNKYSSSSDAASADDSTPLRDNDEAGNEKLKSFYNNVFNFLMVDSPKGSTA
KQYNEACLLKGDIGDRPDHYKDLYKLSAKELSKCLELSPDEVASLTKSHKDYVEHIAT
LVSPKGTYKGSGIATVGGGKFSLMAFLIIKTLRNMGTTLPVEVLIPPGDEGETEFCNK
ILPKYNSKCIYVSDILPRETIEKFVFKGYQFKSLALIASSFENLLLLDADNFPIKPLD
NIFNEEPYVSTGLVMWPDFWRRTTHPLYYDIAGIAVDKKKRVRNSRDDITPPAVYTKD
LKDLSDVPLSDLDGTIPDVSTESGQLMINKTKHLATALLSLFYNVNGPTWYYPIFSQK
AAGEGDKETFIAAANFYGLSFYQVRTRTGVEGYHDEDGFHGVAMLQHDFVQDYGRYLN
AMESIGNKYGGTKSADAIKFDKNYSLEKYTEEFFDNEDLNAKNHVDVMFIHSNFPKFD
PYDLSKSNFLTTNGKPARSYTALKKVKNYDIELENFKVLNEYVCVNKNPFKYLDDLLG
QDKTEWKRVCGYITDRLAFLESTHDKAIAGK"
gene 270247..270633
/locus_tag="YBR016W"
/db_xref="GeneID:852304"
mRNA 270247..270633
/locus_tag="YBR016W"
/product="hypothetical protein"
/transcript_id="NM_001178364.1"
/db_xref="GI:296142686"
/db_xref="GeneID:852304"
CDS 270247..270633
/locus_tag="YBR016W"
/note="Tail-anchored plasma membrane protein containing a
conserved CYSTM module; predicted to be palmitoylated; has
similarity to hydrophilins, which are involved in the
adaptive response to hyperosmotic conditions"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009572.1"
/db_xref="GI:6319490"
/db_xref="SGD:S000000220"
/db_xref="GeneID:852304"
/translation="MSANDYYGGTAGEKSQYSRPSNPPPSSAHQNKTQERGYPPQQQQ
QYYQQQQQHPGYYNQQGYNQQGYNQQGYNQQGYNQQGYNQQGYNQQGHQQPVYVQQQP
PQRGNEGCLAACLAALCICCTMDMLF"
gene complement(270947..273703)
/gene="KAP104"
/locus_tag="YBR017C"
/db_xref="GeneID:852305"
mRNA complement(270947..273703)
/gene="KAP104"
/locus_tag="YBR017C"
/product="Kap104p"
/transcript_id="NM_001178365.1"
/db_xref="GI:296142687"
/db_xref="GeneID:852305"
CDS complement(270947..273703)
/gene="KAP104"
/locus_tag="YBR017C"
/note="Transportin or cytosolic karyopherin beta 2;
functions in the rg-nuclear localization signal-mediated
nuclear import/reimport of mRNA-binding proteins Nab2p and
Hrp1p; regulates asymmetric protein synthesis in daughter
cells during mitosis"
/codon_start=1
/product="Kap104p"
/protein_id="NP_009573.1"
/db_xref="GI:6319491"
/db_xref="SGD:S000000221"
/db_xref="GeneID:852305"
/translation="MASTWKPAEDYVLQLATLLQNCMSPNPEIRNNAMEAMENFQLQP
EFLNYLCYILIEGESDDVLKQHYSLQDLQNNRATAGMLLKNSMLGGNNLIKSNSHDLG
YVKSNIIHGLYNSNNNLVSNVTGIVITTLFSTYYRQHRDDPTGLQMLYQLLELTSNGN
EPSIKALSKIMEDSAQFFQLEWSGNTKPMEALLDSFFRFISNPNFSPVIRSESVKCIN
TVIPLQTQSFIVRLDKFLEIIFQLAQNDENDLVRAQICISFSFLLEFRPDKLVSHLDG
IVQFMLHLITTVNEEKVAIEACEFLHAFATSPNIPEHILQPYVKDIVPILLSKMVYNE
ESIVLLEASNDDDAFLEDKDEDIKPIAPRIVKKKEAGNGEDADDNEDDDDDDDDEDGD
VDTQWNLRKCSAATLDVMTNILPHQVMDIAFPFLREHLGSDRWFIREATILALGAMAE
GGMKYFNDGLPALIPFLVEQLNDKWAPVRKMTCWTLSRFSPWILQDHTEFLIPVLEPI
INTLMDKKKDVQEAAISSVAVFIENADSELVETLFYSQLLTSFDKCLKYYKKKNLIIL
YDAIGRFAEKCALDETAMQIILPPLIEKWALLSDSDKELWPLLECLSCVASSLGERFM
PMAPEVYNRAFRILCHCVELEAKSHQDPTIVVPEKDFIITSLDLIDGLVQGLGAHSQD
LLFPQGTKDLTILKIMLECLQDPVHEVRQSCFALLGDIVYFFNSELVIGNLEDFLKLI
GTEIMHNDDSDGTPAVINAIWALGLISERIDLNTYIIDMSRIILDLFTTNTQIVDSSV
MENLSVTIGKMGLTHPEVFSSGAFANDSNWNKWCLSVNALDDVEEKSSAYMGFLKIIN
LTSTEVTMSNDTIHKIVTGLSSNVEANVFAQEIYTFLMNHSAQISAINFTPDEISFLQ
QFTS"
gene complement(274427..275527)
/gene="GAL7"
/locus_tag="YBR018C"
/db_xref="GeneID:852306"
mRNA complement(274427..275527)
/gene="GAL7"
/locus_tag="YBR018C"
/product="UDP-glucose:hexose-1-phosphate
uridylyltransferase"
/transcript_id="NM_001178366.1"
/db_xref="GI:296142688"
/db_xref="GeneID:852306"
CDS complement(274427..275527)
/gene="GAL7"
/locus_tag="YBR018C"
/EC_number="2.7.7.12"
/note="Galactose-1-phosphate uridyl transferase,
synthesizes glucose-1-phosphate and UDP-galactose from
UDP-D-glucose and alpha-D-galactose-1-phosphate in the
second step of galactose catabolism"
/codon_start=1
/product="UDP-glucose:hexose-1-phosphate
uridylyltransferase"
/protein_id="NP_009574.1"
/db_xref="GI:6319492"
/db_xref="SGD:S000000222"
/db_xref="GeneID:852306"
/translation="MTAEEFDFSSHSHRRYNPLTDSWILVSPHRAKRPWLGQQEAAYK
PTAPLYDPKCYLCPGNKRATGNLNPRYESTYIFPNDYAAVRLDQPILPQNDSNEDNLK
NRLLKVQSVRGNCFVICFSPNHNLTIPQMKQSDLVHIVNSWQALTDDLSREARENHKP
FKYVQIFENKGTAMGCSNLHPHGQAWCLESIPSEVSQELKSFDKYKREHNTDLFADYV
KLESREKSRVVVENESFIVVVPYWAIWPFETLVISKKKLASISQFNQMVKEDLASILK
QLTIKYDNLFETSFPYSMGIHQAPLNATGDELSNSWFHMHFYPPLLRSATVRKFLVGF
ELLGEPQRDLTSEQAAEKLRNLDGQIHYLQRL"
gene complement(276253..278352)
/gene="GAL10"
/locus_tag="YBR019C"
/db_xref="GeneID:852307"
mRNA complement(276253..278352)
/gene="GAL10"
/locus_tag="YBR019C"
/product="bifunctional UDP-glucose 4-epimerase/aldose
1-epimerase"
/transcript_id="NM_001178367.1"
/db_xref="GI:296142689"
/db_xref="GeneID:852307"
CDS complement(276253..278352)
/gene="GAL10"
/locus_tag="YBR019C"
/EC_number="5.1.3.2"
/EC_number="5.1.3.3"
/note="UDP-glucose-4-epimerase, catalyzes the
interconversion of UDP-galactose and UDP-D-glucose in
galactose metabolism; also catalyzes the conversion of
alpha-D-glucose or alpha-D-galactose to their
beta-anomers"
/codon_start=1
/product="bifunctional UDP-glucose 4-epimerase/aldose
1-epimerase"
/protein_id="NP_009575.1"
/db_xref="GI:6319493"
/db_xref="SGD:S000000223"
/db_xref="GeneID:852307"
/translation="MTAQLQSESTSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNL
SNSTYDSVARLEVLTKHHIPFYEVDLCDRKGLEKVFKEYKIDSVIHFAGLKAVGESTQ
IPLRYYHNNILGTVVLLELMQQYNVSKFVFSSSATVYGDATRFPNMIPIPEECPLGPT
NPYGHTKYAIENILNDLYNSDKKSWKFAILRYFNPIGAHPSGLIGEDPLGIPNNLLPY
MAQVAVGRREKLYIFGDDYDSRDGTPIRDYIHVVDLAKGHIAALQYLEAYNENEGLCR
EWNLGSGKGSTVFEVYHAFCKASGIDLPYKVTGRRAGDVLNLTAKPDRAKRELKWQTE
LQVEDSCKDLWKWTTENPFGYQLRGVEARFSAEDMRYDARFVTIGAGTRFQATFANLG
ASIVDLKVNGQSVVLGYENEEGYLNPDSAYIGATIGRYANRISKGKFSLCNKDYQLTV
NNGVNANHSSIGSFHRKRFLGPIIQNPSKDVFTAEYMLIDNEKDTEFPGDLLVTIQYT
VNVAQKSLEMVYKGKLTAGEATPINLTNHSYFNLNKPYGDTIEGTEIMVRSKKSVDVD
KNMIPTGNIVDREIATFNSTKPTVLGPKNPQFDCCFVVDENAKPSQINTLNNELTLIV
KAFHPDSNITLEVLSTEPTYQFYTGDFLSAGYEARQGFAIEPGRYIDAINQENWKDCV
TLKNGETYGSKIVYRFS"
gene 279021..280607
/gene="GAL1"
/locus_tag="YBR020W"
/db_xref="GeneID:852308"
mRNA 279021..280607
/gene="GAL1"
/locus_tag="YBR020W"
/product="galactokinase"
/transcript_id="NM_001178368.1"
/db_xref="GI:296142690"
/db_xref="GeneID:852308"
CDS 279021..280607
/gene="GAL1"
/locus_tag="YBR020W"
/EC_number="2.7.1.6"
/note="Galactokinase, phosphorylates alpha-D-galactose to
alpha-D-galactose-1-phosphate in the first step of
galactose catabolism; expression regulated by Gal4p"
/codon_start=1
/product="galactokinase"
/protein_id="NP_009576.1"
/db_xref="GI:6319494"
/db_xref="SGD:S000000224"
/db_xref="GeneID:852308"
/translation="MTKSHSEEVIVPEFNSSAKELPRPLAEKCPSIIKKFISAYDAKP
DFVARSPGRVNLIGEHIDYCDFSVLPLAIDFDMLCAVKVLNEKNPSITLINADPKFAQ
RKFDLPLDGSYVTIDPSVSDWSNYFKCGLHVAHSFLKKLAPERFASAPLAGLQVFCEG
DVPTGSGLSSSAAFICAVALAVVKANMGPGYHMSKQNLMRITVVAEHYVGVNNGGMDQ
AASVCGEEDHALYVEFKPQLKATPFKFPQLKNHEISFVIANTLVVSNKFETAPTNYNL
RVVEVTTAANVLAATYGVVLLSGKEGSSTNKGNLRDFMNVYYARYHNISTPWNGDIES
GIERLTKMLVLVEESLANKKQGFSVDDVAQSLNCSREEFTRDYLTTSPVRFQVLKLYQ
RAKHVYSESLRVLKAVKLMTTASFTADEDFFKQFGALMNESQASCDKLYECSCPEIDK
ICSIALSNGSYGSRLTGAGWGGCTVHLVPGGPNGNIEKVKEALANEFYKVKYPKITDA
ELENAIIVSKPALGSCLYEL"
gene 281443..283344
/gene="FUR4"
/locus_tag="YBR021W"
/db_xref="GeneID:852309"
mRNA 281443..283344
/gene="FUR4"
/locus_tag="YBR021W"
/product="Fur4p"
/transcript_id="NM_001178369.1"
/db_xref="GI:296142691"
/db_xref="GeneID:852309"
CDS 281443..283344
/gene="FUR4"
/locus_tag="YBR021W"
/note="Uracil permease, localized to the plasma membrane;
expression is tightly regulated by uracil levels and
environmental cues"
/codon_start=1
/product="Fur4p"
/protein_id="NP_009577.1"
/db_xref="GI:6319495"
/db_xref="SGD:S000000225"
/db_xref="GeneID:852309"
/translation="MPDNLSLHLSGSSKRLNSRQLMESSNETFAPNNVDLEKEYKSSQ
SNITTEVYEASSFEEKVSSEKPQYSSFWKKIYYEYVVVDKSILGVSILDSFMYNQDLK
PVEKERRVWSWYNYCYFWLAECFNINTWQIAATGLQLGLNWWQCWITIWIGYGFVGAF
VVLASRVGSAYHLSFPISSRASFGIFFSLWPVINRVVMAIVWYSVQAYIAATPVSLML
KSIFGKDLQDKIPDHFGSPNATTYEFMCFFIFWAASLPFLLVPPHKIRHLFTVKAVLV
PFASFGFLIWAIRRAHGRIALGSLTDVQPHGSAFSWAFLRSLMGCMANFSTMVINAPD
FSRFSKNPNSALWSQLVCIPFLFSITCLIGILVTAAGYEIYGINYWSPLDVLEKFLQT
TYNKGTRAGVFLISFVFAVAQLGTNISANSLSCGTDMSAIFPKFINIKRGSLFCAAMA
LCICPWNLMATSSKFTMALSAYAIFLSSIAGVVCSDYFVVRRGYIKLTHIYSHQKGSF
YMYGNRFGINWRALAAYLCGVAPCLPGFIAEVGAPAIKVSDGAMKLYYLSYWVGYGLS
FSSYTALCYFFPVPGCPVNNIIKDKGWFQRWANVDDFEEEWKDTIERDDLVDDNISVY
EHEHEKTFI"
gene 283738..284271
/gene="POA1"
/locus_tag="YBR022W"
/db_xref="GeneID:852310"
mRNA 283738..284271
/gene="POA1"
/locus_tag="YBR022W"
/product="Poa1p"
/transcript_id="NM_001178370.1"
/db_xref="GI:296142692"
/db_xref="GeneID:852310"
CDS 283738..284271
/gene="POA1"
/locus_tag="YBR022W"
/note="Phosphatase that is highly specific for ADP-ribose
1''-phosphate, a tRNA splicing metabolite; may have a role
in regulation of tRNA splicing"
/codon_start=1
/product="Poa1p"
/protein_id="NP_009578.1"
/db_xref="GI:6319496"
/db_xref="SGD:S000000226"
/db_xref="GeneID:852310"
/translation="MSNITYVKGNILKPKSYARILIHSCNCNGSWGGGIAYQLALRYP
KAEKDYVEVCEKYGSNLLGKCILLPSYENSDLLICCLFTSSFGGSSHGEKQSILNYTK
LALDKLKTFREAKDKTRTSEDSIGDYLNGHIKYPIGEYKLEMPQINSGIFGVPWKETE
RVLEEFSGDMSFTVYQL"
gene complement(284428..287925)
/gene="CHS3"
/locus_tag="YBR023C"
/gene_synonym="CAL1; CSD2; DIT101; KTI2"
/db_xref="GeneID:852311"
mRNA complement(284428..287925)
/gene="CHS3"
/locus_tag="YBR023C"
/gene_synonym="CAL1; CSD2; DIT101; KTI2"
/product="chitin synthase CHS3"
/transcript_id="NM_001178371.1"
/db_xref="GI:296142693"
/db_xref="GeneID:852311"
CDS complement(284428..287925)
/gene="CHS3"
/locus_tag="YBR023C"
/gene_synonym="CAL1; CSD2; DIT101; KTI2"
/EC_number="2.4.1.16"
/note="Chitin synthase III, catalyzes the transfer of
N-acetylglucosamine (GlcNAc) to chitin; required for
synthesis of the majority of cell wall chitin, the chitin
ring during bud emergence, and spore wall chitosan"
/codon_start=1
/product="chitin synthase CHS3"
/protein_id="NP_009579.1"
/db_xref="GI:6319497"
/db_xref="SGD:S000000227"
/db_xref="GeneID:852311"
/translation="MTGLNGDDPDDYYLNLNQDEESLLRSRHSVGSGAPHRQGSLVRP
ERSRLNNPDNPHFYYAQKTQEQMNHLDVLPSSTGVNPNATRRSGSLRSKGSVRSKFSG
RETDSYLLQDMNTTDKKASVKISDEGVAEDEFDKDGDVDNFEESSTQPINKSIKPLRK
ETNDTLSFWQMYCYFITFWAPAPILAFCGMPKKERQMAWREKVALISVILYIGAIVAF
LTFGFTKTVCSSSKLRLKNNEVSTEFVVINGKAYELDTSSRSGIQDVEVDSDTLYGPW
SDAGKDASFLFQNVNGNCHNLITPKSNSSIPHDDDNNLAWYFPCKLKNQDGSSKPNFT
VENYAGWNCHTSKEDRDAFYGLKSKADVYFTWDGIKNSSRNLIVYNGDVLDLDLLDWL
EKDDVDYPVVFDDLKTSNLQGYDLSLVLSNGHERKIARCLSEIIKVGEVDSKTVGCIA
SDVVLYVSLVFILSVVIIKFIIACYFRWTVARKQGAYIVDNKTMDKHTNDIEDWSNNI
QTKAPLKEVDPHLRPKKYSKKSLGHKRASTFDLLKKHSSKMFQFNESVIDLDTSMSSS
LQSSGSYRGMTTMTTQNAWKLSNENKAVHSRNPSTLLPTSSMFWNKATSSPVPGSSLI
QSLDSTIIHPDIVQQPPLDFMPYGFPLIHTICFVTCYSEDEEGLRTTLDSLSTTDYPN
SHKLLMVVCDGLIKGSGNDKTTPEIALGMMDDFVTPPDEVKPYSYVAVASGSKRHNMA
KIYAGFYKYDDSTIPPENQQRVPIITIVKCGTPAEQGAAKPGNRGKRDSQIILMSFLE
KITFDERMTQLEFQLLKNIWQITGLMADFYETVLMVDADTKVFPDALTHMVAEMVKDP
LIMGLCGETKIANKAQSWVTAIQVFEYYISHHQAKAFESVFGSVTCLPGCFSMYRIKS
PKGSDGYWVPVLANPDIVERYSDNVTNTLHKKNLLLLGEDRFLSSLMLKTFPKRKQVF
VPKAACKTIAPDKFKVLLSQRRRWINSTVHNLFELVLIRDLCGTFCFSMQFVIGIELI
GTMVLPLAICFTIYVIIFAIVSKPTPVITLVLLAIILGLPGLIVVITATRWSYLWWMC
VYICALPIWNFVLPSYAYWKFDDFSWGDTRTIAGGNKKAQDENEGEFDHSKIKMRTWR
EFEREDILNRKEESDSFVA"
gene 289445..290350
/gene="SCO2"
/locus_tag="YBR024W"
/db_xref="GeneID:852312"
mRNA 289445..290350
/gene="SCO2"
/locus_tag="YBR024W"
/product="Sco2p"
/transcript_id="NM_001178372.1"
/db_xref="GI:296142694"
/db_xref="GeneID:852312"
CDS 289445..290350
/gene="SCO2"
/locus_tag="YBR024W"
/note="Protein anchored to the mitochondrial inner
membrane, similar to Sco1p and may have a redundant
function with Sco1p in delivery of copper to cytochrome c
oxidase; interacts with Cox2p"
/codon_start=1
/product="Sco2p"
/protein_id="NP_009580.1"
/db_xref="GI:6319498"
/db_xref="SGD:S000000228"
/db_xref="GeneID:852312"
/translation="MLNSSRKYACRSLFRQANVSIKGLFYNGGAYRRGFSTGCCLRSD
NKESPSARQPLDRLQLGDEINEPEPIRTRFFQFSRWKATIALLLLSGGTYAYLSRKRR
LLETEKEADANRAYGSVALGGPFNLTDFNGKPFTEENLKGKFSILYFGFSHCPDICPE
ELDRLTYWISELDDKDHIKIQPLFISCDPARDTPDVLKEYLSDFHPAIIGLTGTYDQV
KSVCKKYKVYFSTPRDVKPNQDYLVDHSIFFYLIDPEGQFIDALGRNYDEQSGLEKIR
EQIQAYVPKEERERRSKKWYSFIFN"
gene complement(290681..291865)
/gene="OLA1"
/locus_tag="YBR025C"
/db_xref="GeneID:852313"
mRNA complement(290681..291865)
/gene="OLA1"
/locus_tag="YBR025C"
/product="Ola1p"
/transcript_id="NM_001178373.1"
/db_xref="GI:296142695"
/db_xref="GeneID:852313"
CDS complement(290681..291865)
/gene="OLA1"
/locus_tag="YBR025C"
/note="P-loop ATPase with similarity to human OLA1 and
bacterial YchF; identified as specifically interacting
with the proteasome; protein abundance increases in
response to hydrogen peroxide and to DNA replication
stress"
/codon_start=1
/product="Ola1p"
/protein_id="NP_009581.1"
/db_xref="GI:6319499"
/db_xref="SGD:S000000229"
/db_xref="GeneID:852313"
/translation="MPPKKQVEEKKVLLGRPGNNLKAGIVGLANVGKSTFFQAITRCP
LGNPANYPFATIDPEEARVIVPSPRFDKLCEIYKKTASEVPAHLTVYDIAGLTKGASA
GEGLGNAFLSHIRSVDSIYQVVRCFDDAEIIHVEGDVDPVRDLEIINQELRLKDIEFA
QKALEGAEKIAKRGGQSLEVKQKKEEMDLITKIIKLLESGQRVANHSWTSKEVEIINS
MFLLTAKPCIYLINLSERDYIRKKNKHLLRIKEWVDKYSPGDLIIPFSVSLEERLSHM
SPEDAEEELKKLQTISALPKIITTMRQKLDLISFFTCGPDEVREWTIRRGTKAPQAAG
VIHNDLMNTFILAQVMKCEDVFEYKDDSAIKAAGKLMQKGKDYVVEDGDIIYFRAGAG
KN"
gene complement(292877..294019)
/gene="ETR1"
/locus_tag="YBR026C"
/gene_synonym="MRF1; MRF1'"
/db_xref="GeneID:852314"
mRNA complement(292877..294019)
/gene="ETR1"
/locus_tag="YBR026C"
/gene_synonym="MRF1; MRF1'"
/product="Etr1p"
/transcript_id="NM_001178374.1"
/db_xref="GI:296142696"
/db_xref="GeneID:852314"
CDS complement(292877..294019)
/gene="ETR1"
/locus_tag="YBR026C"
/gene_synonym="MRF1; MRF1'"
/EC_number="1.3.1.38"
/EC_number="1.3.1.10"
/note="2-enoyl thioester reductase, member of the medium
chain dehydrogenase/reductase family; localized to in
mitochondria, where it has a probable role in fatty acid
synthesis"
/codon_start=1
/product="Etr1p"
/protein_id="NP_009582.1"
/db_xref="GI:6319500"
/db_xref="SGD:S000000230"
/db_xref="GeneID:852314"
/translation="MLPTFKRYMSSSAHQIPKHFKSLIYSTHEVEDCTKVLSVKNYTP
KQDLSQSIVLKTLAFPINPSDINQLQGVYPSRPEKTYDYSTDEPAAIAGNEGVFEVVS
LPSGSSKGDLKLGDRVIPLQANQGTWSNYRVFSSSSDLIKVNDLDLFSAATVSVNGCT
GFQLVSDYIDWNSNGNEWIIQNAGTSSVSKIVTQVAKAKGIKTLSVIRDRDNFDEVAK
VLEDKYGATKVISESQNNDKTFAKEVLSKILGENARVRLALNSVGGKSSASIARKLEN
NALMLTYGGMSKQPVTLPTSLHIFKGLTSKGYWVTEKNKKNPQSKIDTISDFIKMYNY
GHIISPRDEIETLTWNTNTTTDEQLLELVKKGITGKGKKKMVVLEW"
gene complement(294425..296002)
/gene="YPK3"
/locus_tag="YBR028C"
/db_xref="GeneID:852316"
mRNA complement(294425..296002)
/gene="YPK3"
/locus_tag="YBR028C"
/product="Ypk3p"
/transcript_id="NM_001178376.1"
/db_xref="GI:296142697"
/db_xref="GeneID:852316"
CDS complement(294425..296002)
/gene="YPK3"
/locus_tag="YBR028C"
/EC_number="2.7.11.1"
/note="An AGC kinase phosphorylated by cAMP-dependent
protein kinase (PKA) in a TORC1-dependent manner"
/codon_start=1
/product="Ypk3p"
/protein_id="NP_009584.1"
/db_xref="GI:6319502"
/db_xref="SGD:S000000232"
/db_xref="GeneID:852316"
/translation="MIFSLDEELHRVSLDDKKNDIKVDYSSAIYNDINHEQGSSITYE
ESINHLSVHSNAIPLNGMSPAHRMRRRSSAYSKFPILTPPNTRRFSITGSDAMRTNTN
RLSITPQDIISSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLR
KAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLF
YSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYR
DLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEIL
LGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMK
DILNALLKKETAKRWNVDKYWAKTGANNKPTKSKKKKSGAARTSLFTEHFIFRKIDWK
LLESGQLQKTTLGPIVPVITDLELAENFDTEFTSMSYEETYTDSKPININSVSKSPDM
FKGFSYKASGSYLEKYF"
gene complement(296369..297742)
/gene="CDS1"
/locus_tag="YBR029C"
/gene_synonym="CDG1"
/db_xref="GeneID:852317"
mRNA complement(296369..297742)
/gene="CDS1"
/locus_tag="YBR029C"
/gene_synonym="CDG1"
/product="phosphatidate cytidylyltransferase"
/transcript_id="NM_001178377.1"
/db_xref="GI:296142698"
/db_xref="GeneID:852317"
CDS complement(296369..297742)
/gene="CDS1"
/locus_tag="YBR029C"
/gene_synonym="CDG1"
/EC_number="2.7.7.41"
/note="Phosphatidate cytidylyltransferase (CDP-diglyceride
synthetase); an enzyme that catalyzes that conversion of
CTP + phosphate into diphosphate + CDP-diaclglyerol, a
critical step in the synthesis of all major yeast
phospholipids"
/codon_start=1
/product="phosphatidate cytidylyltransferase"
/protein_id="NP_009585.1"
/db_xref="GI:6319503"
/db_xref="SGD:S000000233"
/db_xref="GeneID:852317"
/translation="MSDNPEMKPHGTSKEIVESVTDATSKAIDKLQEELHKDASESVT
PVTKESTAATKESRKYNFFIRTVWTFVMISGFFITLASGHAWCIVLILGCQIATFKEC
IAVTSASGREKNLPLTKTLNWYLLFTTIYYLDGKSLFKFFQATFYEYPVLNFIVTNHK
FICYCLYLMGFVLFVCSLRKGFLKFQFGSLCVTHMVLLLVVFQAHLIIKNVLNGLFWF
LLPCGLVIVNDIFAYLCGITFGKTKLIEISPKKTLEGFLGAWFFTALASIILTRILSP
YTYLTCPVEDLHTNFFSNLTCELNPVFLPQVYRLPPIFFDKVQINSITVKPIYFHALN
LATFASLFAPFGGFFASGLKRTFKVKDFGHSIPGHGGITDRVDCQFIMGSFANLYYET
FISEHRITVDTVLSTILMNLNDKQIIELIDILIRFLSKKGIISAKNFEKLADIFNVTK
KSLTNHS"
gene 298292..299950
/gene="RKM3"
/locus_tag="YBR030W"
/db_xref="GeneID:852318"
mRNA 298292..299950
/gene="RKM3"
/locus_tag="YBR030W"
/product="Rkm3p"
/transcript_id="NM_001178378.1"
/db_xref="GI:296142699"
/db_xref="GeneID:852318"
CDS 298292..299950
/gene="RKM3"
/locus_tag="YBR030W"
/note="Ribosomal lysine methyltransferase specific for
monomethylation of Rpl42ap and Rpl42bp (lysine 40);
nuclear SET domain containing protein"
/codon_start=1
/product="Rkm3p"
/protein_id="NP_009586.1"
/db_xref="GI:6319504"
/db_xref="SGD:S000000234"
/db_xref="GeneID:852318"
/translation="MSVTFKDDVHRILKFVANCNGRFEDSKCDIRESPLGGLGVFAKT
DIAEGESILTLNKSSIFSASNSSIANLLCDSSIDGMLALNIAFIYETTVFRNSSHWYP
FLRTIRIRDDEGHLNLPPSFWHADAKRLLKGTSFDTLFDSLAPEEEIMEGFEIAVDLA
HKWNDEFGLEIPKGFLDVSEENHEEDYNLKLEKFISVAYTLSSRGFEIDAYHETALVP
IADLFNHHVSDPDLKFVSLYDVCDKCGEPDMCKHLIAEEYLEAENLDKNMPKVASMET
RVIDEDLIKSLENDLEKEYSNVTANIEDDDGGIENPDECVDLVLKNDVAQGQEIFNSY
GELSNVFLLARYGFTVPENQYDIVHLGPDFMKILKKEEKYQEKVKWWSQVGHGLFSAW
YAQMRQEDEEDEDGQAKSDNLSDDIESEEEEEEEEGDDSLESWLSQLYIDSSGEPSPS
TWALANLLTLTAVQWESLFSKKATPHISDSIVNEEKLPFLAKKDNPHSKKLLSNLLKE
KQLPCIKGDNSSKITSATKSMLQNARTLVQSEHNILDRCLKRLS"
gene 300166..301254
/gene="RPL4A"
/locus_tag="YBR031W"
/db_xref="GeneID:852319"
mRNA 300166..301254
/gene="RPL4A"
/locus_tag="YBR031W"
/product="ribosomal 60S subunit protein L4A"
/transcript_id="NM_001178379.1"
/db_xref="GI:296142700"
/db_xref="GeneID:852319"
CDS 300166..301254
/gene="RPL4A"
/locus_tag="YBR031W"
/note="Ribosomal 60S subunit protein L4A; N-terminally
acetylated; homologous to mammalian ribosomal protein L4
and bacterial L4; RPL4A has a paralog, RPL4B, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L4A"
/protein_id="NP_009587.1"
/db_xref="GI:6319505"
/db_xref="SGD:S000000235"
/db_xref="GeneID:852319"
/translation="MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNK
NKRQAYAVSEKAGHQTSAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAP
TKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQ
KTKEAVAALKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKA
LRNVPGVETANVASLNLLQLAPGAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTL
PSHIISTSDVTRIINSSEIQSAIRPAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVF
AAEKLGSKKAEKTGTKPAAVFTETLKHD"
gene 301944..304703
/gene="EDS1"
/locus_tag="YBR033W"
/db_xref="GeneID:852321"
mRNA 301944..304703
/gene="EDS1"
/locus_tag="YBR033W"
/product="Eds1p"
/transcript_id="NM_001178381.1"
/db_xref="GI:296142701"
/db_xref="GeneID:852321"
CDS 301944..304703
/gene="EDS1"
/locus_tag="YBR033W"
/note="Putative zinc cluster protein, predicted to be a
transcription factor; not an essential gene; EDS1 has a
paralog, RGT1, that arose from the whole genome
duplication"
/codon_start=1
/product="Eds1p"
/protein_id="NP_009589.1"
/db_xref="GI:6319507"
/db_xref="SGD:S000000237"
/db_xref="GeneID:852321"
/translation="MSHHVPNLYGTPIRDPHERKRNSASMGEVNQSVSSRNCERGSEK
GTKQRKKASHACDQCRRKRIKCRFDKHTGVCQGCLEVGEKCQFIRVPLKRGPAKKRGS
VVSIEKFSSDNDPLQYRPRTHSYPMNSGNNYLPSLARNSSFPSISSLFVPSITAQSQQ
FVKVPYDDIKRRSSLAILGSDSSISTEFGGNYRLDENLNVRQEGKDIVAKGMITPVEE
MGACSSNVRRQGSQSLPIQEQRASPYINPFISGRSRLSSLSYTSEATTSEGNTQGKNQ
CMLTPNSVRSIEKERLNSLTAGFPNKKLGTDGRSDKWDKNSTWKPVYRSSNPSHPSTE
KNVSLNQEASAKPLMLGTYRQFDATSFYKVLGIYYNFFHINFPVIPINKSKFTDMLDP
EKPNVIDEIRQINNEIIQCFKTALEVLVFCKIKQRRSSKSTKSWSRDSLCDFQKGLYY
IQNFNKCIADCFQSLITIKPVLKQNSSVIPSRIKFIYFSTIIVLNFILILAGEESSLL
LGPSVGVFNEFQAHKLFLPFQNTSPMLLLNSNEESGDEILDYAVLFKRLYILLNILDT
LQSFRLGQPKLINLNFGSAIETYFSDKTGHNQVVEKAPVALDNILRNLKLGEFITYFV
LNRKSLQVNVPHHLLFTNQTDYGEFAVEKGEHDNIAGKFETLLKKKEILIRKLLNIEQ
KNDHILENCCNSDAEMKNIGELVCSMITLVSGILDSITNMNAENSVDLDSKPLPNAYF
AQDSEEELMSPTQSITSNLASEENTRCTTKDLMGTVSIFMLPMVEECYNIISLIGPIP
TTLISLYIRNGNMAKGINDRIMTLSTALNELVQITALFNTLEPFRKNAHDRAKRYYVS
ATSSTGCYESVMKSMYSGKCAASNASNVAPSEEENKKILKKFADIGWKLMDDSELGCC
CCFFN"
gene complement(304930..305976)
/gene="HMT1"
/locus_tag="YBR034C"
/gene_synonym="HCP1; ODP1; RMT1"
/db_xref="GeneID:852322"
mRNA complement(304930..305976)
/gene="HMT1"
/locus_tag="YBR034C"
/gene_synonym="HCP1; ODP1; RMT1"
/product="Hmt1p"
/transcript_id="NM_001178382.1"
/db_xref="GI:296142702"
/db_xref="GeneID:852322"
CDS complement(304930..305976)
/gene="HMT1"
/locus_tag="YBR034C"
/gene_synonym="HCP1; ODP1; RMT1"
/EC_number="2.1.1.-"
/note="Nuclear SAM-dependent mono- and asymmetric arginine
dimethylating methyltransferase that modifies hnRNPs,
including Npl3p and Hrp1p, affecting their activity and
nuclear export; methylates U1 snRNP protein Snp1p and
ribosomal protein Rps2p; interacts genetically with genes
encoding components of Rpd3(L) and this interaction is
important for Rpd3 recruitment to the subtelomeric
region."
/codon_start=1
/product="Hmt1p"
/protein_id="NP_009590.1"
/db_xref="GI:6319508"
/db_xref="SGD:S000000238"
/db_xref="GeneID:852322"
/translation="MSKTAVKDSATEKTKLSESEQHYFNSYDHYGIHEEMLQDTVRTL
SYRNAIIQNKDLFKDKIVLDVGCGTGILSMFAAKHGAKHVIGVDMSSIIEMAKELVEL
NGFSDKITLLRGKLEDVHLPFPKVDIIISEWMGYFLLYESMMDTVLYARDHYLVEGGL
IFPDKCSIHLAGLEDSQYKDEKLNYWQDVYGFDYSPFVPLVLHEPIVDTVERNNVNTT
SDKLIEFDLNTVKISDLAFKSNFKLTAKRQDMINGIVTWFDIVFPAPKGKRPVEFSTG
PHAPYTHWKQTIFYFPDDLDAETGDTIEGELVCSPNEKNNRDLNIKISYKFESNGIDG
NSRSRKNEGSYLMH"
gene complement(306269..306955)
/gene="PDX3"
/locus_tag="YBR035C"
/db_xref="GeneID:852323"
mRNA complement(306269..306955)
/gene="PDX3"
/locus_tag="YBR035C"
/product="pyridoxamine-phosphate oxidase PDX3"
/transcript_id="NM_001178383.1"
/db_xref="GI:296142703"
/db_xref="GeneID:852323"
CDS complement(306269..306955)
/gene="PDX3"
/locus_tag="YBR035C"
/EC_number="1.4.3.5"
/note="Pyridoxine (pyridoxamine) phosphate oxidase, has
homologs in E. coli and Myxococcus xanthus; transcription
is under the general control of nitrogen metabolism"
/codon_start=1
/product="pyridoxamine-phosphate oxidase PDX3"
/protein_id="NP_009591.1"
/db_xref="GI:6319509"
/db_xref="SGD:S000000239"
/db_xref="GeneID:852323"
/translation="MTKQAEETQKPIIFAPETYQYDKFTLNEKQLTDDPIDLFTKWFN
EAKEDPRETLPEAITFSSAELPSGRVSSRILLFKELDHRGFTIYSNWGTSRKAHDIAT
NPNAAIVFFWKDLQRQVRVEGITEHVNRETSERYFKTRPRGSKIGAWASRQSDVIKNR
EELDELTQKNTERFKDAEDIPCPDYWGGLRIVPLEIEFWQGRPSRLHDRFVYRRKTEN
DPWKVVRLAP"
gene complement(307185..307345)
/locus_tag="snR161"
/db_xref="GeneID:9164869"
ncRNA complement(307185..307345)
/locus_tag="snR161"
/ncRNA_class="snoRNA"
/product="SNR161"
/note="H/ACA small nucleolar RNA (snoRNA); guides
pseudouridylation of small subunit (SSU) rRNA at positions
U632 and U766"
/db_xref="SGD:S000087162"
/db_xref="GeneID:9164869"
gene 307587..308887
/locus_tag="TLC1"
/db_xref="GeneID:9164870"
ncRNA 307587..308887
/locus_tag="TLC1"
/ncRNA_class="telomerase_RNA"
/product="TLC1"
/note="TLC1 RNA contains a template sequence that Est2p
uses to add irregular repeats of TG(1-3) residues onto a
DNA end; RNA template component of telomerase"
/db_xref="SGD:S000006657"
/db_xref="GeneID:9164870"
gene complement(309081..310313)
/gene="CSG2"
/locus_tag="YBR036C"
/gene_synonym="CLS2"
/db_xref="GeneID:852324"
mRNA complement(309081..310313)
/gene="CSG2"
/locus_tag="YBR036C"
/gene_synonym="CLS2"
/product="mannosylinositol phosphorylceramide synthase
regulatory subunit"
/transcript_id="NM_001178384.1"
/db_xref="GI:296142704"
/db_xref="GeneID:852324"
CDS complement(309081..310313)
/gene="CSG2"
/locus_tag="YBR036C"
/gene_synonym="CLS2"
/note="Endoplasmic reticulum membrane protein, required
for mannosylation of inositolphosphorylceramide and for
growth at high calcium concentrations; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="mannosylinositol phosphorylceramide synthase
regulatory subunit"
/protein_id="NP_009592.1"
/db_xref="GI:6319510"
/db_xref="SGD:S000000240"
/db_xref="GeneID:852324"
/translation="MSTTLLWFSSVIGYVIQTKCLSNIQSKKEISVGPNGTIATPETN
GDNGNSSSLTFYLTFMYFASWLLLVPASRLWEKMRPMFVSDSDSNRNSQFDNNNSGSV
TNEDVDTFSHVLDDPQPRIPAQQQKQKIISVATFKYVAKLTVLALIMIVADLTYNMAL
SLSPAFDVALMQNTAIFEIVTLLYGVCGISRKNYVFRNFLIMMNAVIGILIISYTKAT
CDMLAGKLSVNPNTGELSDPFLFDRLKGALICGLGALIMGPFAVLWNRWFCSNISKNE
NSAVVLVKQSTHMALIGIIGMVILLPFIPKFPSRESVESISLFYNDKSFWFSLLGSII
FGSLPSLISILELNRKAPAEYLTTCNLGAIIFMGLAEWVCEPTQTTIVRWEVIGYIML
TVSLLVLSVTLGEGKYHH"
gene complement(310565..311452)
/gene="SCO1"
/locus_tag="YBR037C"
/gene_synonym="PET161"
/db_xref="GeneID:852325"
mRNA complement(310565..311452)
/gene="SCO1"
/locus_tag="YBR037C"
/gene_synonym="PET161"
/product="Sco1p"
/transcript_id="NM_001178385.1"
/db_xref="GI:296142705"
/db_xref="GeneID:852325"
CDS complement(310565..311452)
/gene="SCO1"
/locus_tag="YBR037C"
/gene_synonym="PET161"
/note="Copper-binding protein of the mitochondrial inner
membrane, required for cytochrome c oxidase activity and
respiration; may function to deliver copper to cytochrome
c oxidase; has similarity to thioredoxins"
/codon_start=1
/product="Sco1p"
/protein_id="NP_009593.1"
/db_xref="GI:6319511"
/db_xref="SGD:S000000241"
/db_xref="GeneID:852325"
/translation="MLKLSRSANLRLVQLPAARLSGNGAKLLTQRGFFTVTRLWQSNG
KKPLSRVPVGGTPIKDNGKVREGSIEFSTGKAIALFLAVGGALSYFFNREKRRLETQK
EAEANRGYGKPSLGGPFHLEDMYGNEFTEKNLLGKFSIIYFGFSNCPDICPDELDKLG
LWLNTLSSKYGITLQPLFITCDPARDSPAVLKEYLSDFHPSILGLTGTFDEVKNACKK
YRVYFSTPPNVKPGQDYLVDHSIFFYLMDPEGQFVDALGRNYDEKTGVDKIVEHVKSY
VPAEQRAKQKEAWYSFLFK"
gene 311898..314789
/gene="CHS2"
/locus_tag="YBR038W"
/db_xref="GeneID:852326"
mRNA 311898..314789
/gene="CHS2"
/locus_tag="YBR038W"
/product="chitin synthase CHS2"
/transcript_id="NM_001178386.1"
/db_xref="GI:296142706"
/db_xref="GeneID:852326"
CDS 311898..314789
/gene="CHS2"
/locus_tag="YBR038W"
/EC_number="2.4.1.16"
/note="Chitin synthase II; catalyzes transfer of
N-acetylglucosamine (GlcNAc) to chitin upon activation of
zymogenic form; required for chitin synthesis in the
primary septum during cytokinesis; localization regulated
by Cdk1p during mitosis"
/codon_start=1
/product="chitin synthase CHS2"
/protein_id="NP_009594.1"
/db_xref="GI:6319512"
/db_xref="SGD:S000000242"
/db_xref="GeneID:852326"
/translation="MTRNPFMVEPSNGSPNRRGASNLSKFYANANSNSRWANPSEESL
EDSYDQSNVFQGLPASPSRAALRYSPDRRHRTQFYRDSAHNSPVAPNRYAANLQESPK
RAGEAVIHLSEGSNLYPRDNADLPVDPYHLSPQQQPSNNLFGSGRLYSQSSKYTMSTT
STTAPSLAEADDEKEKYLTSTTSYDDQSTIFSADTFNETKFELNHPTRQQYVRRANSE
SKRRMVSDLPPPSKKKALLKLDNPIPKGLLDTLPRRNSPEFTEMRYTACTVEPDDFLR
EGYTLRFAEMNRECQIAICITMYNEDKYSLARTIHSIMKNVAHLCKREKSHVWGPNGW
KKVSVILISDGRAKVNQGSLDYLAALGVYQEDMAKASVNGDPVKAHIFELTTQVSINA
DLDYVSKDIVPVQLVFCLKEENKKKINSHRWLFNAFCPVLQPTVVTLVDVGTRLNNTA
IYRLWKVFDMDSNVAGAAGQIKTMKGKWGLKLFNPLVASQNFEYKISNILDKPLESVF
GYISVLPGALSAYRYRALKNHEDGTGPLRSYFLGETQEGRDHDVFTANMYLAEDRILC
WELVAKRDAKWVLKYVKEATGETDVPEDVSEFISQRRRWLNGAMFAAIYAQLHFYQIW
KTKHSVVRKFFLHVEFLYQFIQMLFSWFSIANFVLTFYYLAGSMNLVIKHGEALFIFF
KYLIFCDLASLFIISMGNRPQGAKHLFITSMVILSICATYSLICGFVFAFKSLASGTE
SHKIFVDIVISLLSTYGLYFFSSLMYLDPWHMFTSSIQYFLTLPAFTCTLQIFAFCNT
HDVSWGTKGSTQESKQLSKAIVVQGPDGKQIVETDWPQEVDKKFLEIKSRLKEPEFEE
SSGNEKQSKNDYYRDIRTRIVMIWMLSNLILIMSIIQVFTPQDTDNGYLIFILWSVAA
LAAFRVVGSMAFLFMKYLRIIVSYRNKVEGSGSWEVSKLDLPNVFHKKG"
gene 315575..316510
/gene="ATP3"
/locus_tag="YBR039W"
/db_xref="GeneID:852327"
mRNA 315575..316510
/gene="ATP3"
/locus_tag="YBR039W"
/product="Atp3p"
/transcript_id="NM_001178387.1"
/db_xref="GI:296142707"
/db_xref="GeneID:852327"
CDS 315575..316510
/gene="ATP3"
/locus_tag="YBR039W"
/EC_number="3.6.3.14"
/note="Gamma subunit of the F1 sector of mitochondrial
F1F0 ATP synthase, which is a large, evolutionarily
conserved enzyme complex required for ATP synthesis"
/codon_start=1
/product="Atp3p"
/protein_id="NP_009595.1"
/db_xref="GI:6319513"
/db_xref="SGD:S000000243"
/db_xref="GeneID:852327"
/translation="MLSRIVSNNATRSVMCHQAQVGILYKTNPVRTYATLKEVEMRLK
SIKNIEKITKTMKIVASTRLSKAEKAKISAKKMDEAEQLFYKNAETKNLDVEATETGA
PKELIVAITSDKGLCGSIHSQLAKAVRRHLNDQPNADIVTIGDKIKMQLLRTHPNNIK
LSINGIGKDAPTFQESALIADKLLSVMKAGTYPKISIFYNDPVSSLSFEPSEKPIFNA
KTIEQSPSFGKFEIDTDANVPRDLFEYTLANQMLTAMAQGYAAEISARRNAMDNASKN
AGDMINRYSILYNRTRQAVITNELVDIITGASSLG"
gene 316968..317864
/gene="FIG1"
/locus_tag="YBR040W"
/db_xref="GeneID:852328"
mRNA 316968..317864
/gene="FIG1"
/locus_tag="YBR040W"
/product="Fig1p"
/transcript_id="NM_001178388.1"
/db_xref="GI:296142708"
/db_xref="GeneID:852328"
CDS 316968..317864
/gene="FIG1"
/locus_tag="YBR040W"
/note="Integral membrane protein required for efficient
mating; may participate in or regulate the low affinity
Ca2+ influx system, which affects intracellular signaling
and cell-cell fusion during mating"
/codon_start=1
/product="Fig1p"
/protein_id="NP_009596.1"
/db_xref="GI:6319514"
/db_xref="SGD:S000000244"
/db_xref="GeneID:852328"
/translation="MVAISMIWFFTKRMPRIFALAFNLISIFLLIFLLIGCYNPSNQS
TFLVKYKFDDNSPFYTIIEKSYEKSNTTLGLEEVIIRSGYMGVCIDNIPSQYSSYNNM
TTFSNSICYARKNLSSVPLYRDLEIQLSNIASSSSKTQSSVVLNILKLAQLTSVNVIH
PYVLMATVILTILMFLFILYVTVPKLPFKLAVNKFLLLLSSTIVLTWGIGAMWTHVGI
NASYRLVPSSSMNIITVKKGKKAAVMAWFSFAFLLLDSVVLWLIFLRDRKSLKDEIDN
VPCAQNRYNNYSSDSSTLHSKV"
gene 318266..320275
/gene="FAT1"
/locus_tag="YBR041W"
/db_xref="GeneID:852329"
mRNA 318266..320275
/gene="FAT1"
/locus_tag="YBR041W"
/product="long-chain fatty acid transporter FAT1"
/transcript_id="NM_001178389.1"
/db_xref="GI:296142709"
/db_xref="GeneID:852329"
CDS 318266..320275
/gene="FAT1"
/locus_tag="YBR041W"
/note="Very long chain fatty acyl-CoA synthetase and long
chain fatty acid transporter; activates imported fatty
acids with a preference for very long lengths (C20-C26);
has a separate function in the transport of long chain
fatty acids"
/codon_start=1
/product="long-chain fatty acid transporter FAT1"
/protein_id="NP_009597.2"
/db_xref="GI:41629676"
/db_xref="SGD:S000000245"
/db_xref="GeneID:852329"
/translation="MSPIQVVVFALSRIFLLLFRLIKLIITPIQKSLGYLFGNYFDEL
DRKYRYKEDWYIIPYFLKSVFCYIIDVRRHRFQNWYLFIKQVQQNGDHLAISYTRPMA
EKGEFQLETFTYIETYNIVLRLSHILHFDYNVQAGDYVAIDCTNKPLFVFLWLSLWNI
GAIPAFLNYNTKGTPLVHSLKISNITQVFIDPDASNPIRESEEEIKNALPDVKLNYLE
EQDLMHELLNSQSPEFLQQDNVRTPLGLTDFKPSMLIYTSGTTGLPKSAIMSWRKSSV
GCQVFGHVLHMTNESTVFTAMPLFHSTAALLGACAILSHGGCLALSHKFSASTFWKQV
YLTGATHIQYVGEVCRYLLHTPISKYEKMHKVKVAYGNGLRPDIWQDFRKRFNIEVIG
EFYAATEAPFATTTFQKGDFGIGACRNYGTIIQWFLSFQQTLVRMDPNDDSVIYRNSK
GFCEVAPVGEPGEMLMRIFFPKKPETSFQGYLGNAKETKSKVVRDVFRRGDAWYRCGD
LLKADEYGLWYFLDRMGDTFRWKSENVSTTEVEDQLTASNKEQYAQVLVVGIKVPKYE
GRAGFAVIKLTDNSLDITAKTKLLNDSLSRLNLPSYAMPLFVKFVDEIKMTDNHKILK
KVYREQKLPKGLDGNDTIFWLKNYKRYEVLTAADWEAIDAQTIKL"
gene complement(320416..321609)
/gene="CST26"
/locus_tag="YBR042C"
/gene_synonym="PSI1"
/db_xref="GeneID:852330"
mRNA complement(320416..321609)
/gene="CST26"
/locus_tag="YBR042C"
/gene_synonym="PSI1"
/product="Cst26p"
/transcript_id="NM_001178390.1"
/db_xref="GI:296142710"
/db_xref="GeneID:852330"
CDS complement(320416..321609)
/gene="CST26"
/locus_tag="YBR042C"
/gene_synonym="PSI1"
/EC_number="2.3.-.-"
/note="Protein required for incorporation of stearic acid
into phosphatidylinositol; affects chromosome stability
when overexpressed"
/codon_start=1
/product="Cst26p"
/protein_id="NP_009598.1"
/db_xref="GI:6319516"
/db_xref="SGD:S000000246"
/db_xref="GeneID:852330"
/translation="MLHQKIAHKVRKVVVPGISLLIFFQGCLILLFLQLTYKTLYCRN
DIRKQIGLNKTKRLFIVLVSSILHVVAPSAVRITTENSSVPKGTFFLDLKKKRILSHL
KSNSVAICNHQIYTDWIFLWWLAYTSNLGANVFIILKKSLASIPILGFGMRNYNFIFM
SRKWAQDKITLSNSLAGLDSNARGAGSLAGKSPERITEEGESIWNPEVIDPKQIHWPY
NLILFPEGTNLSADTRQKSAKYAAKIGKKPFKNVLLPHSTGLRYSLQKLKPSIESLYD
ITIGYSGVKQEEYGELIYGLKSIFLEGKYPKLVDIHIRAFDVKDIPLEDENEFSEWLY
KIWSEKDALMERYYSTGSFVSDPETNHSVTDSFKINRIELTEVLILPTLTIIWLVYKL
YCFIF"
gene complement(321876..323945)
/gene="QDR3"
/locus_tag="YBR043C"
/gene_synonym="AQR2"
/db_xref="GeneID:852331"
mRNA complement(321876..323945)
/gene="QDR3"
/locus_tag="YBR043C"
/gene_synonym="AQR2"
/product="Qdr3p"
/transcript_id="NM_001178391.2"
/db_xref="GI:330443424"
/db_xref="GeneID:852331"
CDS complement(321876..323945)
/gene="QDR3"
/locus_tag="YBR043C"
/gene_synonym="AQR2"
/note="Multidrug transporter of the major facilitator
superfamily; member of the 12-spanner drug:H(+) antiporter
DHA1 family; has a role in polyamine homeostasis;
expression is upregulated under polyamine stress; required
for resistance to quinidine, barban, cisplatin, and
bleomycin"
/codon_start=1
/product="Qdr3p"
/protein_id="NP_009599.2"
/db_xref="GI:330443425"
/db_xref="SGD:S000000247"
/db_xref="GeneID:852331"
/translation="MQAQGSQSNVGSLRSNCSDNSLPNNHVMMHCDESSGSPHSEHND
YSYEKTNLESTASNSREHRDNQLSRLKSEEYVVPKNQRRGLLPQLAIIPEFKDARDYP
PMMKKMIVFLIAFSSMMGPMGTSIIFPAINSITTEFKTSVIMVNVSIGVYLLSLGVFP
LWWSSLSELEGRRTTYITSFALLFAFNIGSALAPDINSFIALRMLCGAASASVQSVGA
GTVADLYISEDRGKNLSYYYLGPLLAPLLSPIFGSLLVNRWPWRSTQWFMVILSGCNV
ILLTVLLPETLRKQDSKGAIAQILAERRIQVDNNERGEIQEDYQRGEDETDRIENQVA
TLSTEKHNYVGEVRDQDSLDLESHSSPNTYDGRAGETQLQRIYTEASRSLYEYQLDDS
GIDATTAQVTRIRSTDPKLARSIRENSLRKLQTNLEEQVKKVLSSNGGEIAPKQVSAV
RKVWDTFFVYFIKPLKSLHFLEYPPVALAITFSAISFSTVYFVNMTVEYKYSRPPYNF
KPLYIGLLYIPNSVTYFFASIYGGRWVDMLLKRYKEKYGILAPEARISWNVVTSVISF
PIALLIFGWCLDKKCHWVTPLIGTALFGYAAMMTIGATLSYLVDSLPGKGATGVALNN
LIRQILAATAVFVTTPMLNGMGTGWAFTMLAFIVLGASSVLIILKKHGDYWRENYDLQ
KLYDKID"
gene complement(324341..326059)
/gene="TCM62"
/locus_tag="YBR044C"
/db_xref="GeneID:852332"
mRNA complement(324341..326059)
/gene="TCM62"
/locus_tag="YBR044C"
/product="Tcm62p"
/transcript_id="NM_001178392.2"
/db_xref="GI:330443426"
/db_xref="GeneID:852332"
CDS complement(324341..326059)
/gene="TCM62"
/locus_tag="YBR044C"
/note="Protein involved in the assembly of the
mitochondrial succinate dehydrogenase complex; putative
chaperone"
/codon_start=1
/product="Tcm62p"
/protein_id="NP_009600.2"
/db_xref="GI:330443427"
/db_xref="SGD:S000000248"
/db_xref="GeneID:852332"
/translation="MLRNCLRKLGNHQTKCSVKTLHTPIYRTKNLQVLRDTLSGIKLL
EKIITSSSYNKTLIYEPKYKSKPQVVSSHDTMRLHNVMRELLDSLQVDEATNTRLQSN
RPRKLGRVGLQLFMDCIQDNLTATSTSLTCSLLEHYFKYPEKEVTNGIKAGLRYIRDF
LAKNKIIVKSQNDVDALVEQLTMSSSDSQSIKRVLKAINYELFSDDIVRVINGNKTYD
EVDVSKGWKYPAGILDSNEAYLRSLELPTKKLVSIDKDMLVLMYDGTLRDANKILPTI
TYARKLRKSVLLIVNGDCTGDALTSVTINNNRNKRENNESRIVVLKYSKKANNDLAPQ
ENLDFIKFLRLPCGYDSIYSPEYSPLVPSKMCADKYYGSIESIKATTGEAFLYNSIDA
EAIPNKVPKSFLQNTVTLSIGGHNEIEIDRRRNAIDNCLNNVLCHGLAKGFIPGYGIS
LLKAIPGLNELKANEPNFMTKVGINAVLSAVILPSEVAFKNAYGYNYYEINSLIAGAI
NEKSFPMAKFSPNSEPVNTVKDGNLEPWSKMDSCLAGVETFIELLTSCNTIITCVYKK
PERHKA"
rep_origin 326140..326375
/note="ARS211;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118347"
gene complement(326792..326865)
/locus_tag="tV(UAC)B"
/db_xref="GeneID:852333"
tRNA complement(326792..326865)
/locus_tag="tV(UAC)B"
/product="tRNA-Val"
/note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006769"
/db_xref="GeneID:852333"
LTR 327069..327394
/note="Ty1 LTR"
/db_xref="SGD:S000006817"
LTR 327390..327704
/note="Ty1 LTR"
/db_xref="SGD:S000006818"
gene complement(328173..330092)
/gene="GIP1"
/locus_tag="YBR045C"
/db_xref="GeneID:852334"
mRNA complement(328173..330092)
/gene="GIP1"
/locus_tag="YBR045C"
/product="Gip1p"
/transcript_id="NM_001178393.2"
/db_xref="GI:330443428"
/db_xref="GeneID:852334"
CDS complement(328173..330092)
/gene="GIP1"
/locus_tag="YBR045C"
/note="Meiosis-specific regulatory subunit of the Glc7p
protein phosphatase, regulates spore wall formation and
septin organization, required for expression of some late
meiotic genes and for normal localization of Glc7p"
/codon_start=1
/product="Gip1p"
/protein_id="NP_009601.2"
/db_xref="GI:330443429"
/db_xref="SGD:S000000249"
/db_xref="GeneID:852334"
/translation="METILQPKARPFESLKRKRFREWLRPSTAHGSLLHSDTLDLRDF
AKPNPADTFSNLDSGHCPLVTTPIKYECPDGKSSFFRGDTKFETLFSNRKFYEFKDNL
KRGLKKIRHGRNGHQSEKRCPVVEETKKSVSDNLDKPDNNTPCFDRFHTNSKEFETQF
DHSNRSQNSEKAYLDNESCWNLSEKFIPFNNLKYEDLKHFEENLQSLAPATFTPIESN
ESLDRSDSTRGTKRSIRNDSSDTTSEKRLCLKQYSDEPESDHSMESTPSIYITKEVQE
RIEALSSTDSFLIEKVDFPSNKIGSSASDYESDNEYRNMDEDSINDVTTEKEGNVVIP
DSNTSTVDAMEKPIEVSSALKDDTLDKDIDDASSSYSDDVETTFEPVESEELSDLSDT
SSSGSSKIYTIPTFRGLTNRTNISQILSKVGKADLSQDNLTHLIKSHQKKKRCVNFRN
KRFYDAFNPYVDNEEDAELSDSENISEMDTDLCIKDRSTSSVRFDENSRLLIYKKSKK
LNKDETQSGYSTTEMRSILKTKMNSQHDEESQRASKCDTVGVAQFLHYFQYTEYKRQR
NEAENYRLRGEQLSKYYSEEYPLDFAAVECEDSVNDKSDIILSMRATERNIGRQLKGI
SSQGAQIISLDEDVF"
gene complement(330507..331511)
/gene="ZTA1"
/locus_tag="YBR046C"
/db_xref="GeneID:852335"
mRNA complement(330507..331511)
/gene="ZTA1"
/locus_tag="YBR046C"
/product="Zta1p"
/transcript_id="NM_001178394.1"
/db_xref="GI:296142714"
/db_xref="GeneID:852335"
CDS complement(330507..331511)
/gene="ZTA1"
/locus_tag="YBR046C"
/EC_number="1.6.5.5"
/note="NADPH-dependent quinone reductase, GFP-tagged
protein localizes to the cytoplasm and nucleus; has
similarity to E. coli quinone oxidoreductase and to human
zeta-crystallin"
/codon_start=1
/product="Zta1p"
/protein_id="NP_009602.1"
/db_xref="GI:6319520"
/db_xref="SGD:S000000250"
/db_xref="GeneID:852335"
/translation="MKCTIPEQQKVILIDEIGGYDVIKYEDYPVPSISEEELLIKNKY
TGVNYIESYFRKGIYPCEKPYVLGREASGTVVAKGKGVTNFEVGDQVAYISNSTFAQY
SKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLFAAAGG
VGLILNQLLKMKGAHTIAVASTDEKLKIAKEYGAEYLINASKEDILRQVLKFTNGKGV
DASFDSVGKDTFEISLAALKRKGVFVSFGNASGLIPPFSITRLSPKNITLVRPQLYGY
IADPEEWKYYSDEFFGLVNSKKLNIKIYKTYPLRDYRTAAADIESRKTVGKLVLEIPQ
"
gene 331833..332360
/gene="FMP23"
/locus_tag="YBR047W"
/db_xref="GeneID:852336"
mRNA 331833..332360
/gene="FMP23"
/locus_tag="YBR047W"
/product="Fmp23p"
/transcript_id="NM_001178395.1"
/db_xref="GI:296142715"
/db_xref="GeneID:852336"
CDS 331833..332360
/gene="FMP23"
/locus_tag="YBR047W"
/note="hypothetical protein; proposed to be involved in
iron or copper homeostasis; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="Fmp23p"
/protein_id="NP_009603.1"
/db_xref="GI:6319521"
/db_xref="SGD:S000000251"
/db_xref="GeneID:852336"
/translation="MLINHLSKIRTVRHFSNIKPVLSKEVSRRVIVAPASHFKTSSPN
VKSNIPIHEYKQLPEDSNYIEKHYKELQVFLNEFLIKKLNKTYADFEGDPDELVFQLE
KFIELEVTPRYTNHSAPDGCEERFKSIGDRIVVDRYLDFVKDVRLTLLLNGGHSFIFD
VMLQAKEVFDKMQKE"
gene 332831..333812
/gene="RPS11B"
/locus_tag="YBR048W"
/db_xref="GeneID:852337"
mRNA join(332831..332875,333387..333812)
/gene="RPS11B"
/locus_tag="YBR048W"
/product="ribosomal 40S subunit protein S11B"
/transcript_id="NM_001178396.1"
/db_xref="GI:296142716"
/db_xref="GeneID:852337"
CDS join(332831..332875,333387..333812)
/gene="RPS11B"
/locus_tag="YBR048W"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S11 and
bacterial S17; RPS11B has a paralog, RPS11A, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S11B"
/protein_id="NP_009604.1"
/db_xref="GI:6319522"
/db_xref="SGD:S000000252"
/db_xref="GeneID:852337"
/translation="MSTELTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKT
PKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEK
RHKNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF"
gene complement(334386..336818)
/gene="REB1"
/locus_tag="YBR049C"
/gene_synonym="GRF2"
/db_xref="GeneID:852338"
mRNA complement(334386..336818)
/gene="REB1"
/locus_tag="YBR049C"
/gene_synonym="GRF2"
/product="Reb1p"
/transcript_id="NM_001178397.1"
/db_xref="GI:296142717"
/db_xref="GeneID:852338"
CDS complement(334386..336818)
/gene="REB1"
/locus_tag="YBR049C"
/gene_synonym="GRF2"
/note="RNA polymerase I enhancer binding protein; DNA
binding protein that binds to genes transcribed by both
RNA polymerase I and RNA polymerase II; required for
termination of RNA polymerase I transcription; REB1 has a
paralog, NSI1, that arose from the whole genome
duplication"
/codon_start=1
/product="Reb1p"
/protein_id="NP_009605.1"
/db_xref="GI:6319523"
/db_xref="SGD:S000000253"
/db_xref="GeneID:852338"
/translation="MPSGHNDKNANQESVEEAVLKYVGVGLDHQNHDPQLHTKDLENK
HSKKQNIVESSSDVDVNNNDDSNRNEDNNDDSENISALNANESSSNVDHANSNEQHNA
VMDWYLRQTAHNQQDDEDDENNNNTDNGNDSNNHFSQSDIVVDDDDDKNKKDAGVGVD
DDHQSMAMAAVAAAYTLSKNNNNNNSIANDSNSRKRQHDNGNNHENSQKKRKNNNDDD
DRQIGNVDPELTTLGDADDNDTNNDVIDRDQLVHKAIIDADSITQHPDFQQYLNTAAD
TDDNEKLKHIKDHLMRTHGLNHQNKNHNDDTDDLSNSTKQYSELQKDSMLDSSLNKSR
NYMEVLPKVISQDTQPHQQKSPSHDNEAGSVDNSEISQLLQSAATKASSLVSLSSSSA
TPSTSRSNNSKAFDKAEDAALERFINEYEAIERLTRQQVCERIWSSDRPKDNFWNNIY
KVLPYRSSSSIYKHMRRKYHIFEQRGKWTAEEEQELAKLCAEKEGQWAEIGKTLGRMP
EDCRDRWRNYVKCGTNRASNRWSVEEEELLKKVISDMLEEAQQQQSQLHPNLLEEEQH
LLQDDQNDHRNNDEDDDDTASAAAAAAAAIQEQQQLLQQKQQDDDDAIAAAAAAASSS
LGDNKDEDKPHDSLGIQLDDNSQNSMVPAPSATSTHSKSLSNTIRRHNNKLRKSLMGN
GKLDFKDIINWTIVSERMGGTRSRIQCRYKWNKLVKREAIAKIQTVKDDDMLWIFEKL
RDLGITEDSQVDWDELAALKPGMKLNGLELKLCYERMKKKVKGYKQKSINEISKELVD
YFSSNISMKTEN"
gene complement(337183..338199)
/gene="REG2"
/locus_tag="YBR050C"
/db_xref="GeneID:852340"
mRNA complement(337183..338199)
/gene="REG2"
/locus_tag="YBR050C"
/product="Reg2p"
/transcript_id="NM_001178398.1"
/db_xref="GI:296142718"
/db_xref="GeneID:852340"
CDS complement(337183..338199)
/gene="REG2"
/locus_tag="YBR050C"
/note="Regulatory subunit of the Glc7p type-1 protein
phosphatase; involved with Reg1p, Glc7p, and Snf1p in
regulation of glucose-repressible genes, also involved in
glucose-induced proteolysis of maltose permease"
/codon_start=1
/product="Reg2p"
/protein_id="NP_009606.1"
/db_xref="GI:6319525"
/db_xref="SGD:S000000254"
/db_xref="GeneID:852340"
/translation="MTLSNCDSLDNLFQDPPEEEESSKFVEAVRTLMNRNDMGYPPAA
ANGTYCLKKIKSLNAKQWKINKKRMCMLPAVKKKNFDFHEQRSLILNLNLWKFIKFIN
CSSKNNYNKNNKHVRSSNNTVKNENVLPLQKHKKVDNDQRLENLFWRSWFKARKRRDI
MGKPRERHIKFNDNVEQCIITDEHFIQRLPSTRLNSTDEQRPCSKSELDPCIGNAASK
RSFYDYNSVYVASDAIITTAAATAIISSNSGDYQRGHDVRDVPRNVLLQAGETDFSSV
LRVDSDLKLSNISHHSPVKPSSTSSHSTFIFESETDTDTDTDAETENDIDAYIDTSIP
NLLL"
gene complement(338720..339352)
/gene="RFS1"
/locus_tag="YBR052C"
/db_xref="GeneID:852341"
mRNA complement(338720..339352)
/gene="RFS1"
/locus_tag="YBR052C"
/product="Rfs1p"
/transcript_id="NM_001178400.1"
/db_xref="GI:296142719"
/db_xref="GeneID:852341"
CDS complement(338720..339352)
/gene="RFS1"
/locus_tag="YBR052C"
/note="hypothetical protein; member of a flavodoxin-like
fold protein family that includes Pst2p and Ycp4p; green
fluorescent protein (GFP)-fusion protein localizes to the
cytoplasm in a punctate pattern"
/codon_start=1
/product="Rfs1p"
/protein_id="NP_009608.1"
/db_xref="GI:6319526"
/db_xref="SGD:S000000256"
/db_xref="GeneID:852341"
/translation="MPKVAILIYSVDDIIATLAENEKKGIEIAGGEAEIFQVPDVSYK
TEYATEEGKEAAKVAKTNADFSYKILTRETLVEYDYYLFGIPTKFGNFPAEWKSFWDS
NTGGLWAKGSLHGKIAGLFVSGAISGKGDTEMCIMNAMSTLVHHGVIYVPLGYKNAYK
ELTDVEDVNGSCAWGAGCVSGIDGGRPPSLSELRVHQLQGKAFYDRIKDL"
gene complement(339675..340751)
/locus_tag="YBR053C"
/db_xref="GeneID:852342"
mRNA complement(339675..340751)
/locus_tag="YBR053C"
/product="hypothetical protein"
/transcript_id="NM_001178401.1"
/db_xref="GI:296142720"
/db_xref="GeneID:852342"
CDS complement(339675..340751)
/locus_tag="YBR053C"
/note="hypothetical protein; induced by cell wall
perturbation"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009609.1"
/db_xref="GI:6319527"
/db_xref="SGD:S000000257"
/db_xref="GeneID:852342"
/translation="MSSVGDFEEIILHDLKPYYHVPGAIHSEGITFVKETGTLLWVDI
FKGEVHKVEDIEQPESSHSFFSISRANYGKNASIEYPPNPDELKESVGCIFPILDGAS
QNEIKQVLFGSKFGIGKLDFSKSEWEYVILYSECPELSTDRAYKLRSNDGNVSPDGKY
IYVGLMSDFPFDLEPIGCLLRVDLLAHKIELVWNCLLIPNAIHWDESDQKTMYVTDSL
NFTIWKCPGGDLLKRDELIDVKNSNNQSFESPEPDGSAIWFSKDGKHSGFLFITVWST
SKVQMFDLTNGKLLKEFILPEQTPRVSCCCFVGKDLFVTTANAEINDAVRTNTDKNGG
CIYKIPNVLDGNVPLESTKRQPLH"
gene 343101..344135
/gene="YRO2"
/locus_tag="YBR054W"
/db_xref="GeneID:852343"
mRNA 343101..344135
/gene="YRO2"
/locus_tag="YBR054W"
/product="Yro2p"
/transcript_id="NM_001178402.1"
/db_xref="GI:296142721"
/db_xref="GeneID:852343"
CDS 343101..344135
/gene="YRO2"
/locus_tag="YBR054W"
/note="hypothetical protein with similarity to archaeal
rhodopsins; the authentic, non-tagged protein is detected
in a phosphorylated state in highly purified mitochondria
in high-throughput studies; transcriptionally regulated by
Haa1p"
/codon_start=1
/product="Yro2p"
/protein_id="NP_009610.1"
/db_xref="GI:6319528"
/db_xref="SGD:S000000258"
/db_xref="GeneID:852343"
/translation="MSDYVELLKRGGNEAIKINPPTGADFHITSRGSDWLFTVFCVNL
LFGVILVPLMFRKPVKDRFVYYTAIAPNLFMSIAYFTMASNLGWIPVRAKYNHVQTST
QKEHPGYRQIFYARYVGWFLAFPWPIIQMSLLGGTPLWQIAFNVGMTEIFTVCWLIAA
CVHSTYKWGYYTIGIGAAIVVCISLMTTTFNLVKARGKDVSNVFITFMSVIMFLWLIA
YPTCFGITDGGNVLQPDSATIFYGIIDLLILSILPVLFMPLANYLGIERLGLIFDEEP
AEHVGPVAEKKMPSPASFKSSDSDSSIKEKLKLKKKHKKDKKKAKKAKKAKKAKKAQE
EEEDVATDSE"
gene complement(344602..347301)
/gene="PRP6"
/locus_tag="YBR055C"
/gene_synonym="RNA6; TSM7269"
/db_xref="GeneID:852344"
mRNA complement(344602..347301)
/gene="PRP6"
/locus_tag="YBR055C"
/gene_synonym="RNA6; TSM7269"
/product="Prp6p"
/transcript_id="NM_001178403.1"
/db_xref="GI:296142722"
/db_xref="GeneID:852344"
CDS complement(344602..347301)
/gene="PRP6"
/locus_tag="YBR055C"
/gene_synonym="RNA6; TSM7269"
/note="Splicing factor, component of the U4/U6-U5 snRNP
complex"
/codon_start=1
/product="Prp6p"
/protein_id="NP_009611.1"
/db_xref="GI:6319529"
/db_xref="SGD:S000000259"
/db_xref="GeneID:852344"
/translation="MERPSFLDQEPPAGYVPGIGRGATGFSTKEKQVVSNDDKGRRIP
KRYRENLNNHLQSQPKDDEDDEAANVFKTLELKLAQKKKKRANEKDDDNSVDSSNVKR
QFADLKESLAAVTESEWMDIPDATDFTRRNKRNRIQEQLNRKTYAAPDSLIPGNVDLN
KLTEEREKLLQSQIDENLAQLTKNASNPIQVNKPNAATDALSYLKDLENDRVNSLSDA
TLEDLQKMRTILKSYRKADPTNPQGWIASARLEEKARKFSVAKKIIENGCQECPRSSD
IWLENIRLHESDVHYCKTLVATAINFNPTSPLLWFKAIDLESTTVNKYRVVRKALQEI
PRDEGLWKLAVSFEADKAQVIKMLEKATQFIPQSMDLLTAYTNLQSYHNAKMTLNSFR
KILPQEPEIWIISTLLEERNNPDIPVDKLVSLLKEGLLELSKNGYKATLSAWLKRAEA
LNDAPNSNLTCQAIVYAILEWLRESGEYESELNNVDQILEKMPHSKVQIAVLKKLIQW
DPCDTVLWSRLKMATESYHKIEELLAFFQELLFQTKNSDDIRANMREKSPGLLMMYVS
EYWKAQKGDTRQTLVLIDQIIDFAPHNLDLRFFKIKLLGRSLQLDELRDFFQQTFSSL
EDFKISGTERLYYKYVNFLRYQDLNEEAIKFLNERCLKSFPICHKFFLQLGQIYHSMG
NIEMSRETYLSGTRLVPNCPLLWVSLSKIDEIDLKNPVRARSILDRGLLKNPDDVLFY
IAKIQMEIRLGNLDQAELLVTQALQKFPSNALLWVEQIKLFKHGNKSSLKKTIFQDAL
RRTQNDHRVLLEIGVSFYAEAQYETSLKWLERALKKCSRYGDTWVWLFRTYARLGKDT
VDLYNMFDQCEPTYGPEWIAASKNVKMQYCTPREILLRLMNDK"
gene 347603..347686
/locus_tag="tL(UAA)B2"
/db_xref="GeneID:852345"
tRNA 347603..347686
/locus_tag="tL(UAA)B2"
/product="tRNA-Leu"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006648"
/db_xref="GeneID:852345"
gene 347879..349384
/locus_tag="YBR056W"
/db_xref="GeneID:852346"
mRNA 347879..349384
/locus_tag="YBR056W"
/product="17-beta-hydroxysteroid dehydrogenase-like
protein"
/transcript_id="NM_001178404.1"
/db_xref="GI:296142723"
/db_xref="GeneID:852346"
CDS 347879..349384
/locus_tag="YBR056W"
/EC_number="3.2.1.-"
/note="Putative glycoside hydrolase of the mitochondrial
intermembrane space"
/codon_start=1
/product="17-beta-hydroxysteroid dehydrogenase-like
protein"
/protein_id="NP_009612.1"
/db_xref="GI:6319530"
/db_xref="SGD:S000000260"
/db_xref="GeneID:852346"
/translation="MIGSLRNKFEHFKVSEKGGQNLSTTLPKLPPAKDLDRSTIYKYR
YNYGVNLGALFVLEPWIFSKETICTIDGKEYDSEFDAISQQLKKHSSEDVAKMLSDHY
KKYIDRIDWEWLSKDAHITALRIPIGYWHVEDGKHLDSLPFAPLRKVYELAKPWEKLG
ELINNAKKMSIGVLIDLHGLPGGANCDSHSGSKSGEAAFFHKEKYMTKVYKDILPAII
NTMTLGNENIIGIQVVNEACFDNNPKGQKFYYSEAINTVEKLQPGLPVIISDGWWPQQ
WADWVKEKHFSEIVVIDSHVYRCFSDSDKSKDANSIIKDLPNTVNFPHEDADYTVGEF
SGVLDGQTWNKTSGDRDAIVQKYVQTQADVFSHVASWGWFFWTLQFEYGDGGEWGLAP
MMQKGNLPKRPHGDDLQVDKKKIDSIIHEHEAYWNGKGKNFEHWRFEDGIKTAVDDII
AFRKFDNSLIGRWHSWKSQRRAEYVSAKKDSEFMWEWDQGYQRGLDEFNKY"
LTR 350459..350751
/note="Ty1 LTR"
/db_xref="SGD:S000006819"
gene 350827..350898
/locus_tag="tQ(UUG)B"
/db_xref="GeneID:852347"
tRNA 350827..350898
/locus_tag="tQ(UUG)B"
/product="tRNA-Gln"
/note="Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006691"
/db_xref="GeneID:852347"
gene 351255..351455
/locus_tag="YBR056W-A"
/db_xref="GeneID:1466443"
mRNA 351255..351455
/locus_tag="YBR056W-A"
/product="hypothetical protein"
/transcript_id="NM_001270739.1"
/db_xref="GI:398364542"
/db_xref="GeneID:1466443"
CDS 351255..351455
/locus_tag="YBR056W-A"
/note="hypothetical protein; mRNA identified as translated
by ribosome profiling data; partially overlaps the dubious
ORF YBR056C-B"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001257668.1"
/db_xref="GI:398364543"
/db_xref="SGD:S000028736"
/db_xref="GeneID:1466443"
/translation="MRHQYYQPQPMYYQPQPQPIYIQQGPPPPRNDCCCCCNCGDCCS
AIANVLCCLCLIDLCCSCAGGM"
gene complement(352193..353293)
/gene="MUM2"
/locus_tag="YBR057C"
/db_xref="GeneID:852348"
mRNA complement(352193..353293)
/gene="MUM2"
/locus_tag="YBR057C"
/product="Mum2p"
/transcript_id="NM_001178405.1"
/db_xref="GI:296142724"
/db_xref="GeneID:852348"
CDS complement(352193..353293)
/gene="MUM2"
/locus_tag="YBR057C"
/note="Cytoplasmic protein essential for meiotic DNA
replication and sporulation; interacts with Orc2p, which
is a component of the origin recognition complex"
/codon_start=1
/product="Mum2p"
/protein_id="NP_009613.1"
/db_xref="GI:6319531"
/db_xref="SGD:S000000261"
/db_xref="GeneID:852348"
/translation="MNYMAYDYDPQHSLETSFNNLAFHPHQQSQQQALYESGERNDAR
PGLMNTLGQASKMNNSMLPQGSSASPLTGQHSLNSTTNFNMPPSMNTYNYQNVPQASM
RNTLNHNNIMNGATANDYWLDPMNNMTNNKDTNGNPNDSMSSMSNMTAKTSINSTAFK
NSFVPFNHVTALSMNNVNSNEMNSNKDDRMEALEVELQIKESQIESLENEIQRLKKIF
NEGLNYKQNEHKYEKENCHIPQTFELPASLEVIFRKLSSSLHAKEKELAETKENLESI
LTALALNPTNSVTKYGRYDAESIAHKMVVRLENLTNENKEMAKMLAYGRSKETQIELQ
LAKKENLELREKIASLEAHLASKESSKEDVAN"
gene complement(353672..356017)
/gene="UBP14"
/locus_tag="YBR058C"
/gene_synonym="GID6"
/db_xref="GeneID:852349"
mRNA complement(353672..356017)
/gene="UBP14"
/locus_tag="YBR058C"
/gene_synonym="GID6"
/product="Ubp14p"
/transcript_id="NM_001178406.1"
/db_xref="GI:296142725"
/db_xref="GeneID:852349"
CDS complement(353672..356017)
/gene="UBP14"
/locus_tag="YBR058C"
/gene_synonym="GID6"
/EC_number="3.1.2.15"
/note="Ubiquitin-specific protease that specifically
disassembles unanchored ubiquitin chains; involved in
fructose-1,6-bisphosphatase (Fbp1p) degradation; similar
to human isopeptidase T"
/codon_start=1
/product="Ubp14p"
/protein_id="NP_009614.2"
/db_xref="GI:37362616"
/db_xref="SGD:S000000262"
/db_xref="GeneID:852349"
/translation="MAEAVLENVNVPAVVSKDECIYCFESPYNEPLALNASPKHSLNI
CLNCFQATCNRHVPLHIRVTEYACDTIHSNYLTIAKVEKPKQENVEENNNNKKIKLQV
IETSEDDTHNTIWSLQRFNGENVPRTVLSKSTDSDISSTALEKIEKILKAKSQDFEDK
KNSWVLEISTCPHTENFQIPSKPENTVNLNQCSSCDLTQNLWLCLHCGNIGCGREQIG
IDGHSHALDHYRSNNNHPLAIKLGSLSSSTYDLYCYACDDETRFPDNVNLGSALQIYG
INIQEKIADEKTLVQLQVEQNENWQFRMVDSSGKEFEKLSASKNYGCGLINLGNSCYL
NSVIQSLVNGGVPNWSLDFLGSKFPLDVVYPDNNLKCQWIKLLNAMKCEPELYPNGIK
PTTFKKCIGQNHQEFSSNRQQDAMEFLTFLLDLLDKKFFSSSSSGIPNPNDLVRFMME
DRLQCNICGKVKYSYEPTEAIQIPLEENDEPQDMLERIKAYFEGQTIEFKCANCKEKV
TANKKPGFKSLPQTLILNPIRIRLQNWIPVKTSNELSLPGLIDRDDMLDVSSYLSQGF
DPQTENLLPDEDENRSSFTPNQCSISQLIEMGFTQNASVRALFNTGNQDAESAMNWLF
QHMDDPDLNDPFVPPPNVPKKDKREVDEVSLTSMLSMGLNPNLCRKALILNNGDVNRS
VEWVFNNMDDDGTFPEPEVPNEEQQQKKDLGYSTAKPYALTAVICHKGNSVHSGHYVV
FIRKLVADKWKWVLYNDEKLVAADSIEDMKKNGYIYFYTRC"
gene complement(356324..356566)
/gene="TSC3"
/locus_tag="YBR058C-A"
/db_xref="GeneID:852350"
mRNA complement(356324..356566)
/gene="TSC3"
/locus_tag="YBR058C-A"
/product="Tsc3p"
/transcript_id="NM_001184442.3"
/db_xref="GI:398364554"
/db_xref="GeneID:852350"
CDS complement(356324..356566)
/gene="TSC3"
/locus_tag="YBR058C-A"
/note="Protein that stimulates the activity of serine
palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved
in sphingolipid biosynthesis"
/codon_start=1
/product="Tsc3p"
/protein_id="NP_116327.3"
/db_xref="GI:398364555"
/db_xref="SGD:S000007521"
/db_xref="GeneID:852350"
/translation="MTQHKSSMVYIPTTKEAKRRNGKSEGILNTIEEVVEKLYWTYYI
HLPFYLMASFDSFFLHVFFLTIFSLSFFGILKYCFL"
gene complement(356861..360187)
/gene="AKL1"
/locus_tag="YBR059C"
/db_xref="GeneID:852351"
mRNA complement(356861..360187)
/gene="AKL1"
/locus_tag="YBR059C"
/product="Akl1p"
/transcript_id="NM_001178407.1"
/db_xref="GI:296142727"
/db_xref="GeneID:852351"
CDS complement(356861..360187)
/gene="AKL1"
/locus_tag="YBR059C"
/EC_number="2.7.11.1"
/note="Ser-Thr protein kinase, member (with Ark1p and
Prk1p) of the Ark kinase family; involved in endocytosis
and actin cytoskeleton organization"
/codon_start=1
/product="Akl1p"
/protein_id="NP_009615.1"
/db_xref="GI:6319533"
/db_xref="SGD:S000000263"
/db_xref="GeneID:852351"
/translation="MSITNGTSRSVSAMGHPAVERYTPGHIVCVGTHKVEVVNYLAEG
GFAQIYVVKFLEYLNEFDNTASVPLKIGDVACLKRVLVQDENGLNEMRNEVEVMKKLK
GAPNIVQYFDSNASRRRDGVQGFEVLLLMELCPNKSLLDYMNQRLSTKLTEAEIVKIM
YDVALSISQMHYLPVSLIHRDIKIENVLVDAKNNFKLADFGSTSTCFPIVTTHQDIAL
LTQNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLLFFTTPFEMTGQFAI
LHSKYEFPVNKYSSKLINLIIIMLAENPNLRPNIYQVLYHLCEILNVEVPIEDKYAEG
AYNFSKYTQFQNKLQNVQLQMYQLQQKKIMQNNKLSDSEENLLNDMFLSSFEISSKLP
MNASDGHAAVSRIPSQNVGQELEEEKESQSDQRKSTLSEDKSSRTTSNANSSGTANNP
QEINTIQSPGIEDKSIFENKTPGELYYPSVSELDTYLDKELVKQSSDPTISEQSPRLN
TQSLPQRQKSTSSYSSGGRSMKSTSYGAATIGSDEALANEKTAGINKMKQHKSNNPFP
KMNVAYHSTNELSNDASNFFLEEQQQGQRYQQAQNQTGTQGNTFPDESQYQSRVEQQQ
QQQDQPKGPANYSQRNFYTGRDRSNKPMQLGGTIAGDSGNRRVNFQNISQNYATNSQS
GYLPSQNSPAIPMVRPVISMNQQQAQQIQAQQLQAQQMQAKQQMQAKQQMQVQQQLQV
QQQMQIQNANNNGTYVSDRTNHTTEDMRNAQGGEPPILAGNSANEPMHSSSKNEALLI
ELSPLKEDAGKQSFQDTNEPQTGGIEDAGGSGTIKGSNNNRNGVLNLSLNEMDLSRDD
TGAAVSSFSSSSSSASIQQAKLSGRKGSSKRNNYSTDELGDSMVSSESIDIDLDDARR
GKTAERRPLHNERGHKDQARSSDASKSNQFKSKDFSSVSTRQPRQSLDLNFQEVNLSS
PTLTQEHRNKNDSPAPNSHHSYRVSPHASTAITENKRHSTGHELSTRSNGKHETHRTG
SKQRHDLERYRHSKDKDSNSSITISTSTPSEMRKSFARARQSLDLERVRREAMASSAS
SSGGSNGKRRSFFSVFRSEK"
gene complement(360652..362514)
/gene="ORC2"
/locus_tag="YBR060C"
/gene_synonym="RRR1; SIR5"
/db_xref="GeneID:852352"
mRNA complement(360652..362514)
/gene="ORC2"
/locus_tag="YBR060C"
/gene_synonym="RRR1; SIR5"
/product="origin recognition complex subunit 2"
/transcript_id="NM_001178408.1"
/db_xref="GI:296142728"
/db_xref="GeneID:852352"
CDS complement(360652..362514)
/gene="ORC2"
/locus_tag="YBR060C"
/gene_synonym="RRR1; SIR5"
/note="Subunit of the origin recognition complex, which
directs DNA replication by binding to replication origins
and is also involved in transcriptional silencing;
interacts with Spp1p and with trimethylated histone H3;
phosphorylated by Cdc28p"
/codon_start=1
/product="origin recognition complex subunit 2"
/protein_id="NP_009616.1"
/db_xref="GI:6319534"
/db_xref="SGD:S000000264"
/db_xref="GeneID:852352"
/translation="MLNGEDFVEHNDILSSPAKSRNVTPKRVDPHGERQLRRIHSSKK
NLLERISLVGNERKNTSPDPALKPKTPSKAPRKRGRPRKIQEELTDRIKKDEKDTISS
KKKRKLDKDTSGNVNEESKTSNNKQVMEKTGIKEKREREKIQVATTTYEDNVTPQTDD
NFVSNSPEPPEPATPSKKSLTTNHDFTSPLKQIIMNNLKEYKDSTSPGKLTLSRNFTP
TPVPKNKKLYQTSETKSASSFLDTFEGYFDQRKIVRTNAKSRHTMSMAPDVTREEFSL
VSNFFNENFQKRPRQKLFEIQKKMFPQYWFELTQGFSLLFYGVGSKRNFLEEFAIDYL
SPKIAYSQLAYENELQQNKPVNSIPCLILNGYNPSCNYRDVFKEITDLLVPAELTRSE
TKYWGNHVILQIQKMIDFYKNQPLDIKLILVVHNLDGPSIRKNTFQTMLSFLSVIRQI
AIVASTDHIYAPLLWDNMKAQNYNFVFHDISNFEPSTVESTFQDVMKMGKSDTSSGAE
GAKYVLQSLTVNSKKMYKLLIETQMQNMGNLSANTGPKRGTQRTGVELKLFNHLCAAD
FIASNEIALRSMLREFIEHKMANITKNNSGMEIIWVPYTYAELEKLLKTVLNTL"
gene complement(364787..365719)
/gene="TRM7"
/locus_tag="YBR061C"
/db_xref="GeneID:852353"
mRNA complement(364787..365719)
/gene="TRM7"
/locus_tag="YBR061C"
/product="Trm7p"
/transcript_id="NM_001178409.3"
/db_xref="GI:398364564"
/db_xref="GeneID:852353"
CDS complement(364787..365719)
/gene="TRM7"
/locus_tag="YBR061C"
/EC_number="2.1.1.-"
/note="2'-O-ribose methyltransferase; methylates the
2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at
positions C32 and N34 of the tRNA anticodon loop; crucial
biological role likely modification of tRNA-Phe; interacts
with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34
substrate tRNAs, respectively"
/codon_start=1
/product="Trm7p"
/protein_id="NP_009617.3"
/db_xref="GI:398364565"
/db_xref="SGD:S000000265"
/db_xref="GeneID:852353"
/translation="MGKSSKDKRDLYYRKAKEQGYRARSAFKLLQLNDQFHFLDDPNL
KRVVDLCAAPGSWSQVLSRKLFDESPSSDKEDRKIVSVDLQPMSPIPHVTTLQADITH
PKTLARILKLFGNEKADFVCSDGAPDVTGLHDLDEYVQQQLIMSALQLTACILKKGGT
FVAKIFRGRDIDMLYSQLGYLFDKIVCAKPRSSRGTSLEAFIVCLGYNPPSNWTPKLD
VNTSVDEFFQGCFLNKLCISDKLSHWNEEERNIAEFMACGSLQSFDSDATYHDLPSSV
AGTSSSLDPVQSPTNPPYKKALELKRSGKLTRSV"
gene complement(365976..366600)
/locus_tag="YBR062C"
/db_xref="GeneID:852354"
mRNA complement(join(365976..366502,366585..366600))
/locus_tag="YBR062C"
/product="hypothetical protein"
/transcript_id="NM_001178410.1"
/db_xref="GI:296142730"
/db_xref="GeneID:852354"
CDS complement(join(365976..366502,366585..366600))
/locus_tag="YBR062C"
/note="hypothetical protein that interacts with Msb2p; may
play a role in activation of the filamentous growth
pathway."
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009618.2"
/db_xref="GI:50593118"
/db_xref="SGD:S000000266"
/db_xref="GeneID:852354"
/translation="MSTYEEEHGIQQNSRDYQEVGGTSQEEQRRQVRSQLQGLFQNFG
NTSGEGDAHSDSTLLLRLLSQMLPESLQEEWLQEMDKGKSAGCPDTFAASLPRINKKK
LKATDNCSICYTNYLEDEYPLVVELPHCHHKFDLECLSVWLSRSTTCPLCRDNVMGHR
IINEIDTTEAELEEDWGMYG"
gene complement(366970..368184)
/locus_tag="YBR063C"
/db_xref="GeneID:852356"
mRNA complement(366970..368184)
/locus_tag="YBR063C"
/product="hypothetical protein"
/transcript_id="NM_001178411.1"
/db_xref="GI:296142731"
/db_xref="GeneID:852356"
CDS complement(366970..368184)
/locus_tag="YBR063C"
/note="hypothetical protein; YBR063C is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009619.1"
/db_xref="GI:6319538"
/db_xref="SGD:S000000267"
/db_xref="GeneID:852356"
/translation="MEELGLKSTFPYEYGSDFTMIRTEMLNTTKSETTILFSNIKSIL
AIIWKYSFTFLRSFSDSIKLIIDDVVTIGSRNFAERLQIEAKKNNDQEDIWASTIILG
VIIGYLISSIKRKNTFPIMPTSSPKIDDCRFKTGDTISIVINFNEDCLNNRSDVTEER
NYEESTVLHSKESVLSIGRQNMVTLNQSDENFTYGNFDEYDLLTKDYTTEVLTRSPGS
NPEFKAVVNNTLLDSANETPFKGIEKSINETMVKVPMGCDVSLSHYGRQYAPGNISIM
RSFTARDNTKSVSREIRDICKSFLIIKSQFGDELFLTMFMEKPVFFDNNIPIEITGAY
REKRERLDEVIHKDLIRYDEVQNLTRIRNLLRVKSQKICSRRHNSSVPTKKLLVNDKG
ATSILLWYSNYS"
gene complement(368584..369678)
/gene="ECM2"
/locus_tag="YBR065C"
/gene_synonym="SLT11"
/db_xref="GeneID:852357"
mRNA complement(368584..369678)
/gene="ECM2"
/locus_tag="YBR065C"
/gene_synonym="SLT11"
/product="Ecm2p"
/transcript_id="NM_001178413.3"
/db_xref="GI:398364586"
/db_xref="GeneID:852357"
CDS complement(368584..369678)
/gene="ECM2"
/locus_tag="YBR065C"
/gene_synonym="SLT11"
/note="Pre-mRNA splicing factor, facilitates the
cooperative formation of U2/U6 helix II in association
with stem II in the spliceosome, function may be regulated
by Slu7p"
/codon_start=1
/product="Ecm2p"
/protein_id="NP_009621.3"
/db_xref="GI:398364587"
/db_xref="SGD:S000000269"
/db_xref="GeneID:852357"
/translation="MNDEINEPPPNICEQCLGDEANIRMTKIPQGSECKICTLPFTLY
HFKTSKRSNNIIKTLICVRCATQRNICQCCMLDSRWHIPIQLRDHLISLVNEENVMTE
EAKNDMMKRFLSLKNVKLGGAQITSDPSEADNIVDKLKNILLRATSDGPSTPLIKNTT
ALYKNEKGANEVKNLEKYASVDISHILKKLPLNESFLKNPSTKSFFLYNIDASIPEWK
ITDTVSQLLGIKKWKDGNSLSLIVNHKAKCGGLRFQSSELGERFVSKISETLVTPKGL
KRGVLLIDRFRIFIIPWSSGFSAASFGTNTAENIKLSLSLNKLIQLELGLSFPTKSTD
NAKNDKKKTSKKVHKDRSKKSKPRANKLTI"
gene complement(370037..370699)
/gene="NRG2"
/locus_tag="YBR066C"
/db_xref="GeneID:852358"
mRNA complement(370037..370699)
/gene="NRG2"
/locus_tag="YBR066C"
/product="Nrg2p"
/transcript_id="NM_001178414.1"
/db_xref="GI:296142733"
/db_xref="GeneID:852358"
CDS complement(370037..370699)
/gene="NRG2"
/locus_tag="YBR066C"
/note="Transcriptional repressor; mediates glucose
repression and negatively regulates filamentous growth;
NRG2 has a paralog, NRG1, that arose from the whole genome
duplication"
/codon_start=1
/product="Nrg2p"
/protein_id="NP_009622.1"
/db_xref="GI:6319540"
/db_xref="SGD:S000000270"
/db_xref="GeneID:852358"
/translation="MSIGYKDNLMSTILAKDRKCEFPINFECSPSQITLMPEMFSFNN
ERKYQTLIPLMKTSHLIDDDLKDKLNKCAFDFFSGKQANRTSDGTISRLTASGKTSPI
LPLQNINIVKAENTGNGKSDPYSSIKISKPTKTVIKLKSTKTNTAGQRTRHFCKICST
GFTTSGHLSRHNRIHTGEKNHICPHEGCGQRFSRHDNCNQHYRTHANKKKRNWKRREA
SS"
gene complement(372103..372735)
/gene="TIP1"
/locus_tag="YBR067C"
/db_xref="GeneID:852359"
mRNA complement(372103..372735)
/gene="TIP1"
/locus_tag="YBR067C"
/product="Tip1p"
/transcript_id="NM_001178415.1"
/db_xref="GI:296142734"
/db_xref="GeneID:852359"
CDS complement(372103..372735)
/gene="TIP1"
/locus_tag="YBR067C"
/EC_number="3.1.1.-"
/note="Major cell wall mannoprotein with possible lipase
activity; transcription is induced by heat- and
cold-shock; member of the Srp1p/Tip1p family of
serine-alanine-rich proteins"
/codon_start=1
/product="Tip1p"
/protein_id="NP_009623.1"
/db_xref="GI:6319541"
/db_xref="SGD:S000000271"
/db_xref="GeneID:852359"
/translation="MSVSKIAFVLSAIASLAVADTSAAETAELQAIIGDINSHLSDYL
GLETGNSGFQIPSDVLSVYQQVMTYTDDAYTTLFSELDFDAITKTIVKLPWYTTRLSS
EIAAALASVSPASSEAASSSEAASSSKAASSSEATSSAAPSSSAAPSSSAAPSSSAES
SSKAVSSSVAPTTSSVSTSTVETASNAGQRVNAGAASFGAVVAGAAALLL"
gene complement(373861..375690)
/gene="BAP2"
/locus_tag="YBR068C"
/db_xref="GeneID:852360"
mRNA complement(373861..375690)
/gene="BAP2"
/locus_tag="YBR068C"
/product="Bap2p"
/transcript_id="NM_001178416.4"
/db_xref="GI:398364598"
/db_xref="GeneID:852360"
CDS complement(373861..375690)
/gene="BAP2"
/locus_tag="YBR068C"
/note="High-affinity leucine permease, functions as a
branched-chain amino acid permease involved in the uptake
of leucine, isoleucine and valine; contains 12 predicted
transmembrane domains"
/codon_start=1
/product="Bap2p"
/protein_id="NP_009624.4"
/db_xref="GI:398364599"
/db_xref="SGD:S000000272"
/db_xref="GeneID:852360"
/translation="MLSSEDFGSSGKKETSPDSISIRSFSAGNNFQSSSSEKTYSKQK
SGSDKLIHRFADSFKRAEGSTTRTKQINENTSDLEDGVESITSDSKLKKSMKSRHVVM
MSLGTGIGTGLLVANAKGLHYGGPAALIIGYILVSFVTYFMIQAAGEMAVTYPTLPAN
FNAYSSIFISKSFGFATVWLYCFQWLTVLPLELITASMTIQFWNDKINPDIYILIFYV
FLVFIHFFGVKAYGETEFIFNCCKILMIAGFIILSIVINCGGAGNDGYIGATYWHNPG
AFAGDTSIGRFKNVCYILVTAYFSFGGMELFALSVQEQSNPRKSTPVAAKRSIYRIVV
IYLLTMILIGFNVPYNDDQLMGAGGSATHASPYVLAASIHGVKIVPHIINAVILISVV
SVANSSLYAGPRLICSLAQQGYAPKFLDYVDREGRPLRALIVCCVFGVIAFVAASSKE
EIVFTWLAAIAGLSELFTWTSIMLSHLRFRQAMKVQGRSLDELGYKATTGIWGSIYGV
FFNILVFVAQFWVALAPLGNGGKCDAESFFQNYLAFPIWLAFYFGYMVYNRDFTLLNP
LDKIDLDFHRRIYDPELMRQEDEENKEKLRNMSLMRKAYHFWC"
gene complement(376574..378433)
/gene="TAT1"
/locus_tag="YBR069C"
/gene_synonym="TAP1; VAP1"
/db_xref="GeneID:852361"
mRNA complement(376574..378433)
/gene="TAT1"
/locus_tag="YBR069C"
/gene_synonym="TAP1; VAP1"
/product="Tat1p"
/transcript_id="NM_001178417.1"
/db_xref="GI:296142736"
/db_xref="GeneID:852361"
CDS complement(376574..378433)
/gene="TAT1"
/locus_tag="YBR069C"
/gene_synonym="TAP1; VAP1"
/note="Amino acid transporter for valine, leucine,
isoleucine, and tyrosine; low-affinity tryptophan and
histidine transporter; overexpression confers FK506 and
FTY720 resistance; protein abundance increases in response
to DNA replication stress"
/codon_start=1
/product="Tat1p"
/protein_id="NP_009625.1"
/db_xref="GI:6319543"
/db_xref="SGD:S000000273"
/db_xref="GeneID:852361"
/translation="MDDSVSFIAKEASPAQYSHSLHERTHSEKQKRDFTITEKQDEVS
GQTAEPRRTDSKSILQRKCKEFFDSFKRQLPPDRNSELESQEKNNLTKSIKSRHLVMI
SLGTGIGTGLLVGNGQVLGTAGPAGLVLGYGIASIMLYCIIQAAGELGLCYAGLTGNY
TRYPSILVDPSLGFAVSVVYTIQWLTVLPLQLVTAAMTVKYWTSVNADIFVAVVFVFV
IIINLFGSRGYAEAEFIFNSCKILMVIGFVILAIIINCGGAGDRRYIGAEYWHNPGPF
AHGFKGVCTVFCYAAFSYGGIEVLLLSAAEQENPTKSIPNACKKVVYRILLIYMLTTI
LVCFLVPYNSDELLGSSDSSGSHASPFVIAVASHGVKVVPHFINAVILISVISVANSS
LYSGPRLLLSLAEQGVLPKCLAYVDRNGRPLLCFFVSLVFGCIGFVATSDAEEQVFTW
LLAISSLSQLFIWMSMSLSHIRFRDAMAKQGRSMNEVGYKAQTGYWGSWLAVLIAIFF
LVCQFWVAIAPVNEHGKLNVKVFFQNYLAMPIVLFAYFGHKIYFKSWSFWIPAEKIDL
DSHRNIFVSPSLTEIDKVDDNDDLKEYENSESSENPNSSRSRKFFKRMTNFWC"
gene complement(379221..379934)
/gene="ALG14"
/locus_tag="YBR070C"
/db_xref="GeneID:852362"
mRNA complement(379221..379934)
/gene="ALG14"
/locus_tag="YBR070C"
/product="N-acetylglucosaminyldiphosphodolichol
N-acetylglucosaminyltransferase anchoring subunit ALG14"
/transcript_id="NM_001178418.1"
/db_xref="GI:296142737"
/db_xref="GeneID:852362"
CDS complement(379221..379934)
/gene="ALG14"
/locus_tag="YBR070C"
/note="Component of UDP-GlcNAc transferase required for
the second step of dolichyl-linked oligosaccharide
synthesis; anchors the catalytic subunit Alg13p to the ER
membrane; similar to bacterial and human
glycosyltransferases"
/codon_start=1
/product="N-acetylglucosaminyldiphosphodolichol
N-acetylglucosaminyltransferase anchoring subunit ALG14"
/protein_id="NP_009626.1"
/db_xref="GI:6319544"
/db_xref="SGD:S000000274"
/db_xref="GeneID:852362"
/translation="MKTAYLASLVLIVSTAYVIRLIAILPFFHTQAGTEKDTKDGVNL
LKIRKSSKKPLKIFVFLGSGGHTGEMIRLLENYQDLLLGKSIVYLGYSDEASRQRFAH
FIKKFGHCKVKYYEFMKAREVKATLLQSVKTIIGTLVQSFVHVVRIRFAMCGSPHLFL
LNGPGTCCIISFWLKIMELLLPLLGSSHIVYVESLARINTPSLTGKILYWVVDEFIVQ
WQELRDNYLPRSKWFGILV"
rep_origin 379221..379912
/note="ARS212;
Autonomously Replicating Sequence"
/db_xref="SGD:S000130151"
gene 380411..381046
/locus_tag="YBR071W"
/db_xref="GeneID:852363"
mRNA 380411..381046
/locus_tag="YBR071W"
/product="hypothetical protein"
/transcript_id="NM_001178419.3"
/db_xref="GI:398364614"
/db_xref="GeneID:852363"
CDS 380411..381046
/locus_tag="YBR071W"
/note="hypothetical protein found in the cytoplasm and bud
neck; mRNA expression may be regulated by the cell cycle
and/or cell wall stress; overexpression of YBR071W affects
endocytic protein trafficking"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009627.3"
/db_xref="GI:398364615"
/db_xref="SGD:S000000275"
/db_xref="GeneID:852363"
/translation="MLRRSKNSSTNTNADTKKRQSMHLGSKSSLISLTSEFGHGHSKT
KQKKEEGTAPSQFLSPTNKRSTSSQSKLKRSSLLLDETLLKDYHSAMRHMQTNAAKEE
KLRMAPSPTQSTRSESDASLSSTKSSISSIFSQDNDYSIHDLLYEDIEEMDKTDAFKI
NNTIAIDDSKALFVFCSNDSSSRTASIETLHESNLDNLDMGSSRRTSLDFF"
gene 382030..382674
/gene="HSP26"
/locus_tag="YBR072W"
/db_xref="GeneID:852364"
mRNA 382030..382674
/gene="HSP26"
/locus_tag="YBR072W"
/product="Hsp26p"
/transcript_id="NM_001178420.1"
/db_xref="GI:296142739"
/db_xref="GeneID:852364"
CDS 382030..382674
/gene="HSP26"
/locus_tag="YBR072W"
/note="Small heat shock protein (sHSP) with chaperone
activity; forms hollow, sphere-shaped oligomers that
suppress unfolded proteins aggregation; oligomer
activation requires heat-induced conformational change;
also has mRNA binding activity"
/codon_start=1
/product="Hsp26p"
/protein_id="NP_009628.1"
/db_xref="GI:6319546"
/db_xref="SGD:S000000276"
/db_xref="GeneID:852364"
/translation="MSFNSPFFDFFDNINNEVDAFNRLLGEGGLRGYAPRRQLANTPA
KDSTGKEVARPNNYAGALYDPRDETLDDWFDNDLSLFPSGFGFPRSVAVPVDILDHDN
NYELKVVVPGVKSKKDIDIEYHQNKNQILVSGEIPSTLNEESKDKVKVKESSSGKFKR
VITLPDYPGVDADNIKADYANGVLTLTVPKLKPQKDGKNHVKKIEVSSQESWGN"
gene complement(382860..383021)
/locus_tag="YBR072C-A"
/db_xref="GeneID:1466444"
mRNA complement(382860..383021)
/locus_tag="YBR072C-A"
/product="hypothetical protein"
/transcript_id="NM_001184540.1"
/db_xref="GI:296142740"
/db_xref="GeneID:1466444"
CDS complement(382860..383021)
/locus_tag="YBR072C-A"
/note="hypothetical protein; identified by fungal homology
and RT-PCR"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878048.1"
/db_xref="GI:33438766"
/db_xref="SGD:S000028532"
/db_xref="GeneID:1466444"
/translation="MHILTRSSKNAFPRSRSRQDIHISSHIHRDTSNSALLKILVITR
TRLDSFVKT"
gene 383112..385988
/gene="RDH54"
/locus_tag="YBR073W"
/gene_synonym="TID1"
/db_xref="GeneID:852365"
mRNA 383112..385988
/gene="RDH54"
/locus_tag="YBR073W"
/gene_synonym="TID1"
/product="DNA-dependent ATPase RDH54"
/transcript_id="NM_001178421.4"
/db_xref="GI:398364626"
/db_xref="GeneID:852365"
CDS 383112..385988
/gene="RDH54"
/locus_tag="YBR073W"
/gene_synonym="TID1"
/EC_number="5.99.-.-"
/EC_number="3.6.1.-"
/note="DNA-dependent ATPase; stimulates strand exchange by
modifying the topology of double-stranded DNA; involved in
recombinational repair of DNA double-strand breaks during
mitosis and meiosis; proposed to be involved in crossover
interference; interacts with Dmc1p; stimulates Dmc1p and
Rad51p"
/codon_start=1
/product="DNA-dependent ATPase RDH54"
/protein_id="NP_009629.6"
/db_xref="GI:398364627"
/db_xref="SGD:S000000277"
/db_xref="GeneID:852365"
/translation="MAVISVKPRRREKILQEVKNSSVYQTVFDSGTTQMQIPKYENKP
FKPPRRVGSNKYTQLKPTATAVTTAPISKAKVTVNLKRSISAGPTLNLAKKPNNLSSN
ENTRYFTIMYRKPTTKKHKTWSGDGYATLKASSDKLCFYNEAGKFLGSSMLPSDSDSL
FETLFKAGSNEVQLDYELKENAEIRSAKEALSQNMGNPSPPTTSTTETVPSTKNDGGK
YQMPLSQLFSLNTVKRFKSVTKQTNEHMTTVPKTSQNSKAKKYYPVFDVNKIDNPIVM
NKNAAAEVDVIVDPLLGKFLRPHQREGVKFMYDCLMGLARPTIENPDIDCTTKSLVLE
NDSDISGCLLADDMGLGKTLMSITLIWTLIRQTPFASKVSCSQSGIPLTGLCKKILVV
CPVTLIGNWKREFGKWLNLSRIGVLTLSSRNSPDMDKMAVRNFLKVQRTYQVLIIGYE
KLLSVSEELEKNKHLIDMLVCDEGHRLKNGASKILNTLKSLDIRRKLLLTGTPIQNDL
NEFFTIIDFINPGILGSFASFKRRFIIPITRARDTANRYNEELLEKGEERSKEMIEIT
KRFILRRTNAILEKYLPPKTDIILFCKPYSQQILAFKDILQGARLDFGQLTFSSSLGL
ITLLKKVCNSPGLVGSDPYYKSHIKDTQSQDSYSRSLNSGKLKVLMTLLEGIRKGTKE
KVVVVSNYTQTLDIIENLMNMAGMSHCRLDGSIPAKQRDSIVTSFNRNPAIFGFLLSA
KSGGVGLNLVGASRLILFDNDWNPSVDLQAMSRIHRDGQKKPCFIYRLVTTGCIDEKI
LQRQLMKNSLSQKFLGDSEMRNKESSNDDLFNKEDLKDLFSVHTDTKSNTHDLICSCD
GLGEEIEYPETNQQQNTVELRKRSTTTWTSALDLQKKMNEAATNDDAKKSQYIRQCLV
HYKHIDPARQDELFDEVITDSFTELKDSITFAFVKPGEICLREQ"
gene 386286..389216
/locus_tag="YBR074W"
/gene_synonym="YBR075W"
/db_xref="GeneID:852366"
mRNA 386286..389216
/locus_tag="YBR074W"
/gene_synonym="YBR075W"
/product="hypothetical protein"
/transcript_id="NM_001178422.2"
/db_xref="GI:330443434"
/db_xref="GeneID:852366"
CDS 386286..389216
/locus_tag="YBR074W"
/gene_synonym="YBR075W"
/note="Putative metalloprotease"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009630.3"
/db_xref="GI:330443435"
/db_xref="SGD:S000000278"
/db_xref="GeneID:852366"
/translation="MKLKSVFRSVLKYRKTNLSLLLLITYSIITLLYIFDHERYKLNL
PKEDEHPEFNDLLETAWGDLQIITASFHPYTSKENDKVHDYLLKRVLEITGNSSFASV
SDDKESERSILFQQQDPFNESSRFSRVTYFESSNILVKLEGKNPEEEGLLLSAHFDSV
PTGYGATDDGMGVVSLLANLKYHIKHRPNRTLIFNFNNNEEFGLLGASTYFDHSWSNL
TKYVINLEGTGAGGKAVLFRTSDTSTARIYQQSVKENPFGNSIYQQGFYSRYVRSETD
YKIYEENGMRGWDVAFYKPRNLYHTIKDSIQYTSKASLWHMLHTSLQLSAYVASNSLD
TADQTPACYFDFIGLKFFVISAKTLFYWNCIFLLVSPVVAIGLYLISRDRMTWKSYSW
LSWTRFPLSLAAGIIVQKLFSNDIIRSNPLTFSRNYFWPISAFFTQVIFTSYVLINCS
NFFFPCADMKSLSIIELFIILWTILLFTSKLLYSSDYRYTGLYPLSIFFLLSTIAAIL
RLLALALGMRTRKRLGRECRDHHSNYSSHSQIDMERDGQENLEQPQDQLTSSQDDQAS
IQDDNVSTTSAGPSHNVDEDHGMDSSSQQHDERVPLLKGSNSMEEGLSTRENSLKLEY
TDYAWIIQFLLIVPIPSFILFNSVDVIMDALNHTVQEGSKATFDVLRFGMVGSILIAL
PILPFFYKVNYITISLTALLFLISASKTLLVHPFTNSNPLKVRFSQNIDLSQGNAASV
HVLGREGNFLKPMLQDLPSIKYSSTHINCTSVTNGMELCMYDGMQPNLLSTNGNTNIS
SMVKVHVLHNNRNSTERSPYEPIVAELLLEVKENRACTLTFESRHQAKSPVREITVYQ
KKNSAPQKANITKTIKSASGINELQLHKLDFDQETYHIGVQWFPKLLTDGNVEDDKLG
TKDELSVSISCYWGEYDSESVVNGTAVRKIPAFDELINYAPLSFSFTNEQKGLVIVKD
AIIL"
rep_origin 389212..390371
/note="ARS213;
Autonomously Replicating Sequence"
/db_xref="SGD:S000130152"
gene 390227..391291
/gene="ECM8"
/locus_tag="YBR076W"
/db_xref="GeneID:852368"
mRNA 390227..391291
/gene="ECM8"
/locus_tag="YBR076W"
/product="Ecm8p"
/transcript_id="NM_001178424.2"
/db_xref="GI:330443436"
/db_xref="GeneID:852368"
CDS 390227..391291
/gene="ECM8"
/locus_tag="YBR076W"
/note="Non-essential hypothetical protein"
/codon_start=1
/product="Ecm8p"
/protein_id="NP_009632.2"
/db_xref="GI:330443437"
/db_xref="SGD:S000000280"
/db_xref="GeneID:852368"
/translation="MDYGYFFPAQRIEETNGVDFWIDSNAEFTQSKRPDSSTSTLSRV
LTDTTNVSNNSGSLKRKTIKNKIFPQRKIFNDSENFDFGKANTDCKHVFKSISKQLIF
LPRCFQHHSIRGWMKDRYSEFGYKIKRNQNCPPSACVQALYNTSRSNTEESNPNSLDS
LIMYKYMRYSEKKKELMCRFCQGNNWILAENYLKHLFFAHGILSEFKPHTLYHFESKL
LKIQGKLNFKIQVLKEPEFSKKILNSLTVSIIPSPLAYYTQTLNGGFRRIHVKCPHCE
NWIRLGWCEYDEIIRDSFQDFESLRNLNADYNGMSYIQTRNREDIEGIYENYFTHYIQ
CDLATFRTKCLYVQVITKSN"
gene complement(391805..392293)
/gene="SLM4"
/locus_tag="YBR077C"
/gene_synonym="EGO3; GSE1; NIR1"
/db_xref="GeneID:852369"
mRNA complement(391805..392293)
/gene="SLM4"
/locus_tag="YBR077C"
/gene_synonym="EGO3; GSE1; NIR1"
/product="Slm4p"
/transcript_id="NM_001178425.3"
/db_xref="GI:398364646"
/db_xref="GeneID:852369"
CDS complement(391805..392293)
/gene="SLM4"
/locus_tag="YBR077C"
/gene_synonym="EGO3; GSE1; NIR1"
/note="Component of the EGO complex, which is involved in
the regulation of microautophagy, and of the GSE complex,
which is required for proper sorting of amino acid
permease Gap1p; gene exhibits synthetic genetic
interaction with MSS4"
/codon_start=1
/product="Slm4p"
/protein_id="NP_009633.3"
/db_xref="GI:398364647"
/db_xref="SGD:S000000281"
/db_xref="GeneID:852369"
/translation="MVMLHSKNVKGFLENTLKPYDLHSVDFKTSSLQSSMIITATNGG
ILSYATSNNDVPKNSINEINSVNNLKMMSLLIKDKWSEDENDTEEQHSNSCYPVEIDS
FKTKIYTYEMEDLHTCVAQIPNSDLLLLFIAEGSFPYGLLVIKIERAMRELTDLFGYK
LG"
gene 393123..394742
/gene="ECM33"
/locus_tag="YBR078W"
/db_xref="GeneID:852370"
mRNA join(393123..393180,393511..394742)
/gene="ECM33"
/locus_tag="YBR078W"
/product="Ecm33p"
/transcript_id="NM_001178426.2"
/db_xref="GI:330443438"
/db_xref="GeneID:852370"
CDS join(393123..393180,393511..394742)
/gene="ECM33"
/locus_tag="YBR078W"
/note="GPI-anchored hypothetical protein, has a possible
role in apical bud growth; GPI-anchoring on the plasma
membrane crucial to function; phosphorylated in
mitochondria; similar to Sps2p and Pst1p"
/codon_start=1
/product="Ecm33p"
/protein_id="NP_009634.2"
/db_xref="GI:330443439"
/db_xref="SGD:S000000282"
/db_xref="GeneID:852370"
/translation="MQFKNALTATAILSASALAANSTTSIPSSCSIGTSATATAQADL
DKISGCSTIVGNLTITGDLGSAALASIQEIDGSLTIFNSSSLSSFSADSIKKITGDLN
MQELIILTSASFGSLQEVDSINMVTLPAISTFSTDLQNANNIIVSDTTLESVEGFSTL
KKVNVFNINNNRYLNSFQSSLESVSDSLQFSSNGDNTTLAFDNLVWANNITLRDVNSI
SFGSLQTVNASLGFINNTLPSLNLTQLSKVGQSLSIVSNDELSKAAFSNLTTVGGGFI
IANNTQLKVIDGFNKVQTVGGAIEVTGNFSTLDLSSLKSVRGGANFDSSSSNFSCNAL
KKLQSNGAIQGDSFVCKNGATSTSVKLSSTSTESSKSSATSSASSSGDASNAQANVSA
SASSSSSSSKKSKGAAPELVPATSFMGVVAAVGVALL"
gene complement(395383..398277)
/gene="RPG1"
/locus_tag="YBR079C"
/gene_synonym="TIF32"
/db_xref="GeneID:852371"
mRNA complement(395383..398277)
/gene="RPG1"
/locus_tag="YBR079C"
/gene_synonym="TIF32"
/product="Rpg1p"
/transcript_id="NM_001178427.1"
/db_xref="GI:296142746"
/db_xref="GeneID:852371"
CDS complement(395383..398277)
/gene="RPG1"
/locus_tag="YBR079C"
/gene_synonym="TIF32"
/note="eIF3a subunit of the core complex of translation
initiation factor 3 (eIF3), essential for translation;
part of a Prt1p-Rpg1p-Nip1p subcomplex that stimulates
binding of mRNA and tRNA(i)Met to ribosomes; involved in
translation reinitiation"
/codon_start=1
/product="Rpg1p"
/protein_id="NP_009635.1"
/db_xref="GI:6319553"
/db_xref="SGD:S000000283"
/db_xref="GeneID:852371"
/translation="MAPPPFRPENAIKRADELISVGEKQAALQSLHDFITARRIRWAT
PSTVEPVVFKFLEIGVELKKGKLLKDGLHQYKKLIQGSTEGLVSVGAVARKFIDLVES
KIASEQTRADELQKQEIDDDLEGGVTPENLLISVYESDQSVAGFNDEAITSWLRFTWE
SYRAVLDLLRNNALLEITYSGVVKKTMHFCLKYQRKNEFKRLAEMLRQHLDAANYQQS
KSGNNLVDLSDADTLQRYLDQRFQQVDVSVKLELWHEAYRSIEDVFHLMKISKRAPKP
STLANYYENLVKVFFVSGDPLLHTTAWKKFYKLYSTNPRATEEEFKTYSSTIFLSAIS
TQLDEIPSIGYDPHLRMYRLLNLDAKPTRKEMLQSIIEDESIYGKVDEELKELYDIIE
VNFDVDTVKQQLENLLVKLSSKTYFSQYIAPLRDVIMRRVFVAASQKFTTVSQSELYK
LATLPAPLDLSAWDIEKSLLQAAVEDYVSITIDHESAKVTFAKDPFDIFASTASKEVS
EEENTEPEVQEEKEETDEALGPQETEDGEEKEEESDPVIIRNSYIHNKLLELSNVLHD
VDSFNNASYMEKVRIARETLIKKNKDDLEKISKIVDERVKRSQEQKQKHMEHAALHAE
QDAEVRQQRILEEKAAIEAKLEEEAHRRLIEKKKREFEAIKEREITKMITEVNAKGHV
YIDPNEAKSLDLDTIKQVIIAEVSKNKSELESRMEYAMKKLDHTERALRKVELPLLQK
EVDKLQETDTANYEAMKKKIVDAAKAEYEARMADRKNLVMVYDDYLKFKEHVSGTKES
ELAAIRNQKKAELEAAKKARIEEVRKRRYEEAIARRKEEIANAERQKRAQELAEATRK
QREIEEAAAKKSTPYSFRAGNREPPSTPSTLPKATVSPDKAKLDMIAQKQREMEEAIE
QRLAGRTAGGSSPATPATPATPATPTPSSGPKKMTMAEKLRAKRLAKGGR"
gene complement(398614..400890)
/gene="SEC18"
/locus_tag="YBR080C"
/gene_synonym="ANU4"
/db_xref="GeneID:852372"
mRNA complement(398614..400890)
/gene="SEC18"
/locus_tag="YBR080C"
/gene_synonym="ANU4"
/product="Sec18p"
/transcript_id="NM_001178428.3"
/db_xref="GI:398364664"
/db_xref="GeneID:852372"
CDS complement(398614..400890)
/gene="SEC18"
/locus_tag="YBR080C"
/gene_synonym="ANU4"
/note="ATPase required for vesicular transport between ER
and Golgi, the 'priming' step in homotypic vacuole fusion,
autophagy, and protein secretion; releases Sec17p from
SNAP complexes; has similarity to mammalian NSF"
/codon_start=1
/product="Sec18p"
/protein_id="NP_009636.3"
/db_xref="GI:398364665"
/db_xref="SGD:S000000284"
/db_xref="GeneID:852372"
/translation="MFKIPGFGKAAANHTPPDMTNMDTRTRHLKVSNCPNNSYALANV
AAVSPNDFPNNIYIIIDNLFVFTTRHSNDIPPGTIGFNGNQRTWGGWSLNQDVQAKAF
DLFKYSGKQSYLGSIDIDISFRARGKAVSTVFDQDELAKQFVRCYESQIFSPTQYLIM
EFQGHFFDLKIRNVQAIDLGDIEPTSAVATGIETKGILTKQTQINFFKGRDGLVNLKS
SNSLRPRSNAVIRPDFKFEDLGVGGLDKEFTKIFRRAFASRIFPPSVIEKLGISHVKG
LLLYGPPGTGKTLIARKIGTMLNAKEPKIVNGPEILSKYVGSSEENIRNLFKDAEAEY
RAKGEESSLHIIIFDELDSVFKQRGSRGDGTGVGDNVVNQLLAKMDGVDQLNNILVIG
MTNRKDLIDSALLRPGRFEVQVEIHLPDEKGRLQIFDIQTKKMRENNMMSDDVNLAEL
AALTKNFSGAEIEGLVKSASSFAINKTVNIGKGATKLNTKDIAKLKVTREDFLNALND
VTPAFGISEEDLKTCVEGGMMLYSERVNSILKNGARYVRQVRESDKSRLVSLLIHGPA
GSGKTALAAEIALKSGFPFIRLISPNELSGMSESAKIAYIDNTFRDAYKSPLNILVID
SLETLVDWVPIGPRFSNNILQMLKVALKRKPPQDRRLLIMTTTSAYSVLQQMDILSCF
DNEIAVPNMTNLDELNNVMIESNFLDDAGRVKVINELSRSCPNFNVGIKKTLTNIETA
RHDEDPVNELVELMTQSA"
gene complement(401253..405251)
/gene="SPT7"
/locus_tag="YBR081C"
/gene_synonym="GIT2"
/db_xref="GeneID:852373"
mRNA complement(401253..405251)
/gene="SPT7"
/locus_tag="YBR081C"
/gene_synonym="GIT2"
/product="Spt7p"
/transcript_id="NM_001178429.1"
/db_xref="GI:296142748"
/db_xref="GeneID:852373"
CDS complement(401253..405251)
/gene="SPT7"
/locus_tag="YBR081C"
/gene_synonym="GIT2"
/note="Subunit of the SAGA transcriptional regulatory
complex, involved in proper assembly of the complex; also
present as a C-terminally truncated form in the SLIK/SALSA
transcriptional regulatory complex"
/codon_start=1
/product="Spt7p"
/protein_id="NP_009637.1"
/db_xref="GI:6319555"
/db_xref="SGD:S000000285"
/db_xref="GeneID:852373"
/translation="MTERIPIKNYQRTNAKALLKLTEKLFNKNFFDLYLTSQQLVVLE
YLLSISSEEDKLKAWDYFLKGNIALNVEKSFPLTQEEEHHGAVSPAVDTRSDDVSSQT
IKDNNNTNTNTSISNENHVENEIEDKGDNAIANEDNFVNNDESDNVEEDLFKLDLEDL
KQQISGTRFIGNLSLKIRYVLWQCAIDYIYCDRNEFGDENDTEYTLLDVEEKEEEEIG
KNEKPQNKEGISKFAEDEDYDDEDENYDEDSTDVKNVDDPPKNLDSISSSNIEIDDER
RLVLNISISKETLSKLKTNNVEEIMGNWNKIYHSFEYDKETMIKRLKLEESDKMIEKG
KKKRSRSDLEAATDEQDRENTNDEPDTNQKLPTPEGSTFSDTGNKRPKQSNLDLTVNL
GIENLSLKHLLSSIQQKKSQLGISDYELKHLIMDVRKNRSKWTSDERIGQEELYEACE
KVVLELRNYTEHSTPFLNKVSKREAPNYHQIIKKSMDLNTVLKKLKSFQYDSKQEFVD
DIMLIWKNCLTYNSDPSHFLRGHAIAMQKKSLQLIRMIPNITIRNRADLEKEIEDMEK
DKDYELDEEEEVAGSGRKGLNMGAHMLAKENGKVSEKDSSKTVKDEAPTNDDKLTSVI
PEGEKEKDKTASSTVTVHENVNKNEIKENGKNEEQDMVEESSKTEDSSKDADAAKKDT
EDGLQDKTAENKEAGENNEEEEDDDDEDEDEDMVDSQSYLLEKDDDRDDLEISVWKTV
TAKVRAEICLKRTEYFKNGKLNSDSEAFLKNPQRMKRFDQLFLEYKEQKALESYRQKI
EQNSIMKNGFGTVLKQEDDDQLQFHNDHSLNGNEAFEKQPNDIELDDTRFLQEYDISN
AIPDIVYEGVNTKTLDKMEDASVDRMLQNGINKQSRFLANKDLGLTPKMNQNITLIQQ
IRHICHKISLIRMLQSPLSAQNSRSNPNAFLNNHIYNYTIIDDSLDIDPVSQLPTHDY
KNNRELIWKFMHKNISKVAMANGFETAHPSAINMLTEIAGDYLSNLIKTLKLHHETNS
LNRGTNVEMLQTTLLENGINRPDDLFSYVESEFGKKTKKLQDIKQKLESFLRALLRPT
LQELSERNFEDESQSFFTGDFASELTGEDFFGFRELGLEKEFGVLSSSVPLQLLTTQF
QTVDGETKVQAKKIQPEESDSIVYKKITKGMLDAGSFWNTLLPLLQKDYERSKAYIAK
QSKSSANDKTSMTSTEDNSFALLEEDQFVSKKTATKARLPPTGKISTTYKKKPIASAF
ILPEEDLENDVKADPTTTVNAKVGAENDGDSSLFLRTPQPLDPLDMDDAFDDTNMGSN
SSFSLSLPRLNQ"
gene 405878..405949
/locus_tag="tR(UCU)B"
/db_xref="GeneID:852374"
tRNA 405878..405949
/locus_tag="tR(UCU)B"
/product="tRNA-Arg"
/note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon UCU (converted to mcm5-UCU in the mature
tRNA); decodes AGA codons into arginine; one of 19 nuclear
tRNAs for arginine; part of dicistronic transcript with
tD(GUC)B"
/db_xref="SGD:S000006708"
/db_xref="GeneID:852374"
gene 405960..406031
/locus_tag="tD(GUC)B"
/db_xref="GeneID:852375"
tRNA 405960..406031
/locus_tag="tD(GUC)B"
/product="tRNA-Asp"
/note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006530"
/db_xref="GeneID:852375"
gene complement(406628..407169)
/gene="UBC4"
/locus_tag="YBR082C"
/db_xref="GeneID:852376"
mRNA complement(join(406628..407027,407123..407169))
/gene="UBC4"
/locus_tag="YBR082C"
/product="E2 ubiquitin-conjugating protein UBC4"
/transcript_id="NM_001178430.1"
/db_xref="GI:296142749"
/db_xref="GeneID:852376"
CDS complement(join(406628..407027,407123..407169))
/gene="UBC4"
/locus_tag="YBR082C"
/EC_number="6.3.2.19"
/note="Ubiquitin-conjugating enzyme (E2), mediates
degradation of abnormal or excess proteins, including
calmodulin and histone H3; interacts with many SCF
ubiquitin protein ligases; component of the cellular
stress response"
/codon_start=1
/product="E2 ubiquitin-conjugating protein UBC4"
/protein_id="NP_009638.1"
/db_xref="GI:6319556"
/db_xref="SGD:S000000286"
/db_xref="GeneID:852376"
/translation="MSSSKRIAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADS
PYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNINANGNICLDILKDQWSPALTLSK
VLLSICSLLTDANPDDPLVPEIAHIYKTDRPKYEATAREWTKKYAV"
rep_origin 407876..408108
/note="ARS214;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118348"
gene 409169..410629
/gene="TEC1"
/locus_tag="YBR083W"
/gene_synonym="ROC1"
/db_xref="GeneID:852377"
mRNA 409169..410629
/gene="TEC1"
/locus_tag="YBR083W"
/gene_synonym="ROC1"
/product="Tec1p"
/transcript_id="NM_001178431.3"
/db_xref="GI:398364680"
/db_xref="GeneID:852377"
CDS 409169..410629
/gene="TEC1"
/locus_tag="YBR083W"
/gene_synonym="ROC1"
/note="Transcription factor targeting filamentation genes
and Ty1 expression; Ste12p activation of most
filamentation gene promoters depends on Tec1p and Tec1p
transcriptional activity is dependent on its association
with Ste12p; binds to TCS elements upstream of
filamentation genes, which are regulated by
Tec1p/Ste12p/Dig1p complex; competes with Dig2p for
binding to Ste12p/Dig1p; positive regulator of
chronological life span; TEA/ATTS DNA-binding domain
family member"
/codon_start=1
/product="Tec1p"
/protein_id="NP_009639.3"
/db_xref="GI:398364681"
/db_xref="SGD:S000000287"
/db_xref="GeneID:852377"
/translation="MSLKEDDFGKDNSRNIESYTGRIFDVYIQKDSYSQSALDDMFPE
AVVSTAACVKNEAEDNINLIDTHPQFELVNTGLGAKSDDLKSPSAKATFTDKQRKNEV
PNISVSNYFPGQSSETSSTTESWTIGCDKWSEKVEEAFLEALRLIMKNGTTKIKIRNA
NFGRNELISLYIKHKTNEFRTKKQISSHIQVWKKTIQNKIKDSLTLSSKEKELLHLIE
HGAEQTTENSNLFYDIFEEIIDSLPSVSDSGSLTPKNLYVSNNSSGLSVHSKLLTPIT
ASNEKKIENFIKTNAASQAKTPLIYAKHIYENIDGYKCVPSKRPLEQLSPTELHQGDR
PNKASFSNKKAILESAKKIEIEQRKIINKYQRISRIQEHESNPEFSSNSNSGSEYESE
EEVVPRSATVTQLQSRPVPYYKNNGMPYSLSKVRGRPMYPRPAEDAYNANYIQGLPQY
QTSYFSQLLLSSPQHYEHSPHQRNFTPSNQSHGNFY"
gene 411054..413981
/gene="MIS1"
/locus_tag="YBR084W"
/db_xref="GeneID:852378"
mRNA 411054..413981
/gene="MIS1"
/locus_tag="YBR084W"
/product="trifunctional formate-tetrahydrofolate
ligase/methenyltetrahydrofolate
cyclohydrolase/methylenetetrahydrofolate dehydrogenase
MIS1"
/transcript_id="NM_001178432.1"
/db_xref="GI:296142751"
/db_xref="GeneID:852378"
CDS 411054..413981
/gene="MIS1"
/locus_tag="YBR084W"
/EC_number="1.5.1.5"
/EC_number="3.5.4.9"
/EC_number="6.3.4.3"
/note="Mitochondrial C1-tetrahydrofolate synthase,
involved in interconversion between different oxidation
states of tetrahydrofolate (THF); provides activities of
formyl-THF synthetase, methenyl-THF cyclohydrolase, and
methylene-THF dehydrogenase"
/codon_start=1
/product="trifunctional formate-tetrahydrofolate
ligase/methenyltetrahydrofolate
cyclohydrolase/methylenetetrahydrofolate dehydrogenase
MIS1"
/protein_id="NP_009640.1"
/db_xref="GI:6319558"
/db_xref="SGD:S000000288"
/db_xref="GeneID:852378"
/translation="MLSRLSLLSNSRAFQQARWRIYRLKVSPTVHASQYHILSGRKLA
QSIREKANDEIQAIKLKHPNFKPTLKIIQVGARPDSSTYVRMKLKASKDSNVDCIIEK
LPAEITEVELLKKISDINDDDSIHGLLIQLPLPRHLDETTITNAVDFKKDVDGFHRYN
AGELAKKGGKPYFIPCTPYGCMKLLEEAHVKLDGKNAVVLGRSSIVGNPIASLLKNAN
ATVTVCHSHTRNIAEVVSQADIVIAACGIPQYVKSDWIKEGAVVIDVGINYVPDISKK
SGQKLVGDVDFDSVKEKTSYITPVPGGVGPMTVAMLVSNVLLAAKRQFVESEKLPVIK
PLPLHLESPVPSDIDISRAQSPKHIKQVAEELGIHSHELELYGHYKAKISPNIFKRLE
SRENGKYVLVAGITPTPLGEGKSTTTMGLVQALSAHLGKPSIANVRQPSLGPTLGVKG
GAAGGGYAQVIPMDEFNLHLTGDIHAISAANNLLAAAIDTRMFHEATQKNDSTFYKRL
VPRKKGIRKFTPSMQRRLKRLDIEKEDPDALTPEEVKRFARLNINPDTITIRRVVDIN
DRMLRQITIGEAATEKGFTRTTGFDITVASELMAILALSKSLHEMKERIGRMVIGADY
DNKPVTVEDIGCTGALTALLRDAIKPNLMQTLEGTPVMVHAGPFANISIGASSVIADL
MALKLVGSEKNPLNDKNIHEPGYVVTEAGFDFAMGGERFFDIKCRSSGLVPDAVVLVA
TVRALKSHGGAPNVKPGQSLPKEYTEENIDFVAKGVSNLVKQIENIKTFGIPVVVAIN
RFETDSQAEIEVIKKAALNAGASHAVTSNHWMEGGKGAVELAHAVVDATKEPKNFNFL
YDVNSSIEDKLTSIVQKMYGGAKIEVSPEAQKKIDTYKKQGFGNLPICIAKTQYSLSH
DPSLKGVPRGFTFPIRDVRASIGAGYLYALAAEIQTIPGLSTYAGYMAVEVDDDGEIE
GLF"
gene complement(414186..415261)
/gene="RPL19A"
/locus_tag="YBR084C-A"
/db_xref="GeneID:852379"
mRNA complement(join(414186..414753,415260..415261))
/gene="RPL19A"
/locus_tag="YBR084C-A"
/product="ribosomal 60S subunit protein L19A"
/transcript_id="NM_001180057.1"
/db_xref="GI:296142752"
/db_xref="GeneID:852379"
CDS complement(join(414186..414753,415260..415261))
/gene="RPL19A"
/locus_tag="YBR084C-A"
/note="Ribosomal 60S subunit protein L19A; rpl19a and
rpl19b single null mutations result in slow growth, while
the double null mutation is lethal; homologous to
mammalian ribosomal protein L19, no bacterial homolog;
RPL19A has a paralog, RPL19B, that arose from the whole
genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L19A"
/protein_id="NP_009641.1"
/db_xref="GI:6319559"
/db_xref="SGD:S000002156"
/db_xref="GeneID:852379"
/translation="MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKL
VKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVL
RRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAE
ARRLKNRAARDRRAQRVAEKRDALLKEDA"
gene 415983..416906
/gene="AAC3"
/locus_tag="YBR085W"
/gene_synonym="ANC3"
/db_xref="GeneID:852380"
mRNA 415983..416906
/gene="AAC3"
/locus_tag="YBR085W"
/gene_synonym="ANC3"
/product="Aac3p"
/transcript_id="NM_001178433.3"
/db_xref="GI:398364706"
/db_xref="GeneID:852380"
CDS 415983..416906
/gene="AAC3"
/locus_tag="YBR085W"
/gene_synonym="ANC3"
/note="Mitochondrial inner membrane ADP/ATP translocator;
exchanges cytosolic ADP for mitochondrially synthesized
ATP; expressed under anaerobic conditions; similar to
Aac1p; has roles in maintenance of viability and in
respiration; AAC3 has a paralog, PET9, that arose from the
whole genome duplication"
/codon_start=1
/product="Aac3p"
/protein_id="NP_009642.3"
/db_xref="GI:398364707"
/db_xref="SGD:S000000289"
/db_xref="GeneID:852380"
/translation="MSSDAKQQETNFAINFLMGGVSAAIAKTAASPIERVKILIQNQD
EMIKQGTLDKKYSGIVDCFKRTAKQEGLISFWRGNTANVIRYFPTQALNFAFKDKIKL
MFGFKKEEGYGKWFAGNLASGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGARQFN
GLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGSLDGSFLA
SFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYNGAIDCLKKIVASEGVGSLFKG
CGANILRSVAGAGVISMYDQLQMILFGKKFK"
rep_origin 417784..418079
/note="ARS215;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118349"
gene complement(418907..419164)
/locus_tag="YBR085C-A"
/db_xref="GeneID:852381"
mRNA complement(418907..419164)
/locus_tag="YBR085C-A"
/product="hypothetical protein"
/transcript_id="NM_001184443.1"
/db_xref="GI:296142754"
/db_xref="GeneID:852381"
CDS complement(418907..419164)
/locus_tag="YBR085C-A"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and to the
nucleus; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_061491.1"
/db_xref="GI:9755326"
/db_xref="SGD:S000007522"
/db_xref="GeneID:852381"
/translation="MSSALYKQSTNFTHSTGSFLQSAPVELTTVSGYQEFLKKQEKKN
YEIQTVLSEDKSHGYVLKDGEVIANIIGEAKDYLLDLAGQA"
gene complement(420201..423041)
/gene="IST2"
/locus_tag="YBR086C"
/db_xref="GeneID:852382"
mRNA complement(420201..423041)
/gene="IST2"
/locus_tag="YBR086C"
/product="Ist2p"
/transcript_id="NM_001178434.1"
/db_xref="GI:296142755"
/db_xref="GeneID:852382"
CDS complement(420201..423041)
/gene="IST2"
/locus_tag="YBR086C"
/note="Plasma membrane protein that may be involved in
osmotolerance, localizes to the mother cell in
small-budded cells and to the bud in medium- and
large-budded cells; mRNA is transported to the bud tip by
an actomyosin-driven process"
/codon_start=1
/product="Ist2p"
/protein_id="NP_009643.2"
/db_xref="GI:27808701"
/db_xref="SGD:S000000290"
/db_xref="GeneID:852382"
/translation="MSQTITSLDPNCVIVFNKTSSANEKSLNVEFKRLNIHSIIEPGH
DLQTSYAFIRIHQDNAKPLFSFLQNLDFIESIIPYHDTELSDDLHKLISISKSKILEA
PKQYELYNLSNLTNNPKQSLYFAFLQNYIKWLIPFSFFGLSIRFLSNFTYEFNSTYSL
FAILWTLSFTAFWLYKYEPFWSDRLSKYSSFSTIEFLQDKQKAQKKASSVIMLKKCCF
IPVALLFGAILLSFQLYCFALEIFIKQIYNGPMISILSFLPTILICTFTPVLTVIYNK
YFVEPMTKWENHSSVVNAKKSKEAKNFVIIFLSSYVPLLITLFLYLPMGHLLTAEIRT
KVFNAFSILARLPTHDSDFIIDTKRYEDQFFYFIVINQLIQFSMENFVPSLVSIAQQK
INGPNPNFVKAESEIGKAQLSSSDMKIWSKVKSYQTDPWGATFDLDANFKKLLLQFGY
LVMFSTIWPLAPFICLIVNLIVYQVDLRKAVLYSKPEYFPFPIYDKPSSVSNTQKLTV
GLWNSVLVMFSILGCVITATLTYMYQSCNIPGVGAHTSIHTNKAWYLANPINHSWINI
VLYAVFIEHVSVAIFFLFSSILKSSHDDVANGIVPKHVVNVQNPPKQEVFEKIPSPEF
NSNNEKELVQRKGSANEKLHQELGEKQPASSANGYEAHAATHANNDPSSLSSASSPSL
SSSSSSSKTGVVKAVDNDTAGSAGKKPLATESTEKRNSLVKVPTVGSYGVAGATLPET
IPTSKNYYLRFDEDGKSIRDAKSSAESSNATNNNTLGTESKLLPDGDAVDALSRKIDQ
IPKIAVTGGENNENTQAKDDAATKTPLIKDANIKPVVNAAVNDNQSKVSVATEQTKKT
EVSTKNGPSRSISTKETKDSARPSNNNTTTTTTTDATQPHHHHHHHRHRDAGVKNVTN
NSKTTESSSSSSAAKEKPKHKKGLLHKLKKKL"
gene 423765..424829
/gene="RFC5"
/locus_tag="YBR087W"
/db_xref="GeneID:852383"
mRNA 423765..424829
/gene="RFC5"
/locus_tag="YBR087W"
/product="replication factor C subunit 5"
/transcript_id="NM_001178435.3"
/db_xref="GI:398364718"
/db_xref="GeneID:852383"
CDS 423765..424829
/gene="RFC5"
/locus_tag="YBR087W"
/note="Subunit of heteropentameric Replication factor C
(RF-C), which is a DNA binding protein and ATPase that
acts as a clamp loader of the proliferating cell nuclear
antigen (PCNA) processivity factor for DNA polymerases
delta and epsilon"
/codon_start=1
/product="replication factor C subunit 5"
/protein_id="NP_009644.3"
/db_xref="GI:398364719"
/db_xref="SGD:S000000291"
/db_xref="GeneID:852383"
/translation="MSLWVDKYRPKSLNALSHNEELTNFLKSLSDQPRDLPHLLLYGP
NGTGKKTRCMALLESIFGPGVYRLKIDVRQFVTASNRKLELNVVSSPYHLEITPSDMG
NNDRIVIQELLKEVAQMEQVDFQDSKDGLAHRYKCVIINEANSLTKDAQAALRRTMEK
YSKNIRLIMVCDSMSPIIAPIKSRCLLIRCPAPSDSEISTILSDVVTNERIQLETKDI
LKRIAQASNGNLRVSLLMLESMALNNELALKSSSPIIKPDWIIVIHKLTRKIVKERSV
NSLIECRAVLYDLLAHCIPANIILKELTFSLLDVETLNTTNKSSIIEYSSVFDERLSL
GNKAIFHLEGFIAKVMCCLD"
gene complement(424990..425766)
/gene="POL30"
/locus_tag="YBR088C"
/db_xref="GeneID:852385"
mRNA complement(424990..425766)
/gene="POL30"
/locus_tag="YBR088C"
/product="Pol30p"
/transcript_id="NM_001178436.1"
/db_xref="GI:296142757"
/db_xref="GeneID:852385"
CDS complement(424990..425766)
/gene="POL30"
/locus_tag="YBR088C"
/note="Proliferating cell nuclear antigen (PCNA),
functions as the sliding clamp for DNA polymerase delta;
may function as a docking site for other proteins required
for mitotic and meiotic chromosomal DNA replication and
for DNA repair"
/codon_start=1
/product="Pol30p"
/protein_id="NP_009645.1"
/db_xref="GI:6319564"
/db_xref="SGD:S000000292"
/db_xref="GeneID:852385"
/translation="MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSR
VLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILL
FEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINI
MITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKG
SSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLAPKFNDEE"
gene complement(426190..426489)
/gene="NHP6B"
/locus_tag="YBR089C-A"
/gene_synonym="YBR090C-A"
/db_xref="GeneID:852386"
mRNA complement(426190..426489)
/gene="NHP6B"
/locus_tag="YBR089C-A"
/gene_synonym="YBR090C-A"
/product="Nhp6bp"
/transcript_id="NM_001180058.2"
/db_xref="GI:339046260"
/db_xref="GeneID:852386"
CDS complement(426190..426489)
/gene="NHP6B"
/locus_tag="YBR089C-A"
/gene_synonym="YBR090C-A"
/note="High-mobility group (HMG) protein, binds to and
remodels nucleosomes; involved in recruiting FACT and
other chromatin remodelling complexes to the chromosomes;
functionally redundant with Nhp6Ap; homologous to
mammalian HMGB1 and HMGB2; NHP6B has a paralog, NHP6A,
that arose from the whole genome duplication"
/codon_start=1
/product="Nhp6bp"
/protein_id="NP_009647.2"
/db_xref="GI:339046261"
/db_xref="SGD:S000002157"
/db_xref="GeneID:852386"
/translation="MAATKEAKQPKEPKKRTTRRKKDPNAPKRGLSAYMFFANENRDI
VRSENPDVTFGQVGRILGERWKALTAEEKQPYESKAQADKKRYESEKELYNATRA"
gene complement(426333..427058)
/locus_tag="YBR090C"
/db_xref="GeneID:852387"
mRNA complement(join(426333..426516,426874..427058))
/locus_tag="YBR090C"
/product="hypothetical protein"
/transcript_id="NM_001178438.4"
/db_xref="GI:398364746"
/db_xref="GeneID:852387"
CDS complement(join(426333..426516,426874..427058))
/locus_tag="YBR090C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and
nucleus"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009648.4"
/db_xref="GI:398364747"
/db_xref="SGD:S000000294"
/db_xref="GeneID:852387"
/translation="MVPAPGSRAFPSPVFLGGVFFVFFFRWRGNYKVQQVRLRQYWEF
TLWETAPNTKQKNDFFAKTLTYIKLALWPQLKKQSNQRNQRRGPPGERRILTPLRGAC
QLICSLLMKTETLSVPRILT"
gene complement(427155..427484)
/gene="TIM12"
/locus_tag="YBR091C"
/gene_synonym="MRS5"
/db_xref="GeneID:852388"
mRNA complement(427155..427484)
/gene="TIM12"
/locus_tag="YBR091C"
/gene_synonym="MRS5"
/product="Tim12p"
/transcript_id="NM_001178439.1"
/db_xref="GI:296142760"
/db_xref="GeneID:852388"
CDS complement(427155..427484)
/gene="TIM12"
/locus_tag="YBR091C"
/gene_synonym="MRS5"
/note="Essential protein of the inner mitochondrial
membrane, peripherally localized; component of the TIM22
complex, which is a twin-pore translocase that mediates
insertion of numerous multispanning inner membrane
proteins"
/codon_start=1
/product="Tim12p"
/protein_id="NP_009649.1"
/db_xref="GI:6319567"
/db_xref="SGD:S000000295"
/db_xref="GeneID:852388"
/translation="MSFFLNSLRGNQEVSQEKLDVAGVQFDAMCSTFNNILSTCLEKC
IPHEGFGEPDLTKGEQCCIDRCVAKMHYSNRLIGGFVQTRGFGPENQLRHYSRFVAKE
IADDSKK"
gene complement(427698..429101)
/gene="PHO3"
/locus_tag="YBR092C"
/db_xref="GeneID:852389"
mRNA complement(427698..429101)
/gene="PHO3"
/locus_tag="YBR092C"
/product="Pho3p"
/transcript_id="NM_001178440.1"
/db_xref="GI:296142761"
/db_xref="GeneID:852389"
CDS complement(427698..429101)
/gene="PHO3"
/locus_tag="YBR092C"
/EC_number="3.1.3.2"
/note="Constitutively expressed acid phosphatase similar
to Pho5p; brought to the cell surface by transport
vesicles; hydrolyzes thiamin phosphates in the periplasmic
space, increasing cellular thiamin uptake; expression is
repressed by thiamin"
/codon_start=1
/product="Pho3p"
/protein_id="NP_009650.1"
/db_xref="GI:6319568"
/db_xref="SGD:S000000296"
/db_xref="GeneID:852389"
/translation="MFKSVVYSVLAAALVNAGTIPLGELADVAKIGTQEDIFPFLGGA
GPYFSFPGDYGISRDLPEGCEMKQLQMLARHGERYPTYSKGATIMKTWYKLSNYTRQF
NGSLSFLNDDYEFFIRDDDDLEMETTFANSDNVLNPYTGEMDAKRHAREFLAQYGYMF
ENQTSFPIFAASSERVHDTAQYFIDGLGDQFNISLQTVSEAMSAGANTLSAGNACPGW
DEDANDDILDKYDTTYLDDIAKRLNKENKGLNLTSKDANTLFAWCAYELNARGYSDVC
DIFTEDELVRYSYGQDLVSFYQDGPGYDMIRSVGANLFNATLKLLKQSETQDLKVWLS
FTHDTDILNYLTTAGIIDDKNNLTAEYVPFMGNTFHKSWYVPQGARVYTEKFQCSNDT
YVRYVINDAVVPIETCSTGPGFSCEINDFYDYAEKRVAGTDFLKVCNVSSVSNVTELT
FYWDWNTTHYNDTLLKQ"
gene complement(429548..430951)
/gene="PHO5"
/locus_tag="YBR093C"
/db_xref="GeneID:852390"
mRNA complement(429548..430951)
/gene="PHO5"
/locus_tag="YBR093C"
/product="Pho5p"
/transcript_id="NM_001178441.3"
/db_xref="GI:398364756"
/db_xref="GeneID:852390"
CDS complement(429548..430951)
/gene="PHO5"
/locus_tag="YBR093C"
/EC_number="3.1.3.2"
/note="Repressible acid phosphatase (1 of 3) that also
mediates extracellular nucleotide-derived phosphate
hydrolysis; secretory pathway derived cell surface
glycoprotein; induced by phosphate starvation and
coordinately regulated by PHO4 and PHO2"
/codon_start=1
/product="Pho5p"
/protein_id="NP_009651.3"
/db_xref="GI:398364757"
/db_xref="SGD:S000000297"
/db_xref="GeneID:852390"
/translation="MFKSVVYSILAASLANAGTIPLGKLADVDKIGTQKDIFPFLGGA
GPYYSFPGDYGISRDLPEGCEMKQLQMVGRHGERYPTVSLAKTIKSTWYKLSNYTRQF
NGSLSFLNDDYEFFIRDDDDLEMETTFANSDDVLNPYTGEMNAKRHARDFLAQYGYMV
ENQTSFAVFTSNSKRCHDTAQYFIDGLGDQFNITLQTVSEAESAGANTLSACNSCPAW
DYDANDDIVNEYDTTYLDDIAKRLNKENKGLNLTSTDASTLFSWCAFEVNAKGYSDVC
DIFTKDELVHYSYYQDLHTYYHEGPGYDIIKSVGSNLFNASVKLLKQSEIQDQKVWLS
FTHDTDILNFLTTAGIIDDKNNLTAEYVPFMGNTFHRSWYVPQGARVYTEKFQCSNDT
YVRYVINDAVVPIETCSTGPGFSCEINDFYDYAEKRVAGTDFLKVCNVSSVSNSTELT
FYWDWNTTHYNASLLRQ"
gene 432036..434297
/gene="PBY1"
/locus_tag="YBR094W"
/db_xref="GeneID:852391"
mRNA 432036..434297
/gene="PBY1"
/locus_tag="YBR094W"
/product="Pby1p"
/transcript_id="NM_001178442.2"
/db_xref="GI:330443444"
/db_xref="GeneID:852391"
CDS 432036..434297
/gene="PBY1"
/locus_tag="YBR094W"
/note="Putative tubulin tyrosine ligase associated with
P-bodies; forms cytoplasmic foci upon DNA replication
stress"
/codon_start=1
/product="Pby1p"
/protein_id="NP_009652.2"
/db_xref="GI:330443445"
/db_xref="SGD:S000000298"
/db_xref="GeneID:852391"
/translation="MRVLITNDDGPLSDQFSPYIRPFIQHIKRNYPEWKITVCVPHVQ
KSWVGKAHLAGKNLTAQFIYSKVDAEDNTFWGPFIQPQIRSENSKLPYVLNAEIPKDT
IEWILIDGTPASCANIGLHLLSNEPFDLVLSGPNVGRNTSAAYITSSGTVGGAMESVI
TGNTKAIAISWAYFNGLKNVSPLLMEKASKRSLDVIKHLVKNWDPKTDLYSINIPLVE
SLSDDTKVYYAPIWENRWIPIFNGPHINLENSFAEIEDGNESSSISFNWAPKFGAHKD
SIHYMDEYKDRTVLTDAEVIESEMISVTPMKATFKGVNHLLGELKLTEEENNLSKTNN
LIVVSIDPMEYIYKPLTHALKKYLPQVEIVSNLPEFDNGGCEKEMKVFHYGDYEQLDM
DKLMELPNNYFTNSYIYRKALIRKHFLSHTIQTYTAKNPESILKKAYLESFTIDLDYA
EFLDDALDENWELRQELENESQDKWWIVKPSMSDKGQGIRVFKTIEDLQAIFDSFDDE
DSEAEESGNDDDADDVNGEFMDNNKVNISQLRHFIIQEYLTNPLLLASMDNRKFHIRC
YVVCRGDLQVFVYDRMLALFAAKPFVPLDPYAYSVTDLKDLECHLTNTCLQSKKKDKD
SSVLEFDSIEEIPNERKSNIKEQIHSITNDVFLAAVNVNRLNFQPLPNAFETYGVDFL
IDSNYEVKLLEINAFPDFKQTGKDLKNLIDELFDDTVKYCVTPIFNENRNKTDDETDP
NFVKVIDYTSNGW"
gene complement(434406..435698)
/gene="RXT2"
/locus_tag="YBR095C"
/gene_synonym="RAF60"
/db_xref="GeneID:852392"
mRNA complement(434406..435698)
/gene="RXT2"
/locus_tag="YBR095C"
/gene_synonym="RAF60"
/product="Rxt2p"
/transcript_id="NM_001178443.1"
/db_xref="GI:296142764"
/db_xref="GeneID:852392"
CDS complement(434406..435698)
/gene="RXT2"
/locus_tag="YBR095C"
/gene_synonym="RAF60"
/note="Subunit of the histone deacetylase Rpd3L complex;
possibly involved in cell fusion and invasive growth"
/codon_start=1
/product="Rxt2p"
/protein_id="NP_009653.2"
/db_xref="GI:37362619"
/db_xref="SGD:S000000299"
/db_xref="GeneID:852392"
/translation="MTIRSSMKNNAELESKSVLANESNIISTFTRRIIKEKSGNYQVL
KRSLDGKLIYPEATGISSNRGNKLLQRSEVVTRRDLNNSKPMIEQTVFYNGSEHRLLQ
TNIVTDSRRKRIKFTPDINVEPVLVGDENDIDGSEKEDENITDEYYGEEDDDDLSKLV
NVKEILTPILSLGDIINHKTISRTFSSPILKNLALQIILMIEKEQMSVVRYSQFLEVF
LGDHPEPIYESNLNLPSYNHNLTLPEDRGASDEDDINNKNNINEVNSNSLSTEAGHIN
NGMEEFGEEDPFFALPRLEQSNALLSLLPSSSGSASISTLTAAEQQQLNEEIESARQL
SQIALQRNKEFIRNLQKIRKSVIKANRIRGRILNWSREYLGISDDDITIPVALRVVKR
GLISATTNKTTNFEEEIENTMEDGVVDDNEPDEEANRA"
gene 436021..436713
/locus_tag="YBR096W"
/db_xref="GeneID:852393"
mRNA 436021..436713
/locus_tag="YBR096W"
/product="hypothetical protein"
/transcript_id="NM_001178444.3"
/db_xref="GI:398364770"
/db_xref="GeneID:852393"
CDS 436021..436713
/locus_tag="YBR096W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the ER"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009654.3"
/db_xref="GI:398364771"
/db_xref="SGD:S000000300"
/db_xref="GeneID:852393"
/translation="MGVCTIFRWLFAAYLLSSYKSLPGAYFVRFYYYVIQNLFLPMFT
GFETENIKKLEKNEYGCFSYTSLDTYASPFECDFYFHKSNSTYFAELDISRGNLMCKI
FQKLMLNSKHYPYIPVANVFTNFLKEIKPFQKYSVSSRIICWDEKWIYVMSRFTIKKG
TVLCSLSLTKYVLKDGRKTIKPKDALEYCGLYNEKVAKISEDNLKLLTERCGFHETVP
LENLSQEYCSEI"
gene 436951..441315
/gene="VPS15"
/locus_tag="YBR097W"
/gene_synonym="GRD8; VAC4; VPL19; VPS40"
/db_xref="GeneID:852394"
mRNA 436951..441315
/gene="VPS15"
/locus_tag="YBR097W"
/gene_synonym="GRD8; VAC4; VPL19; VPS40"
/product="Vps15p"
/transcript_id="NM_001178445.2"
/db_xref="GI:330443446"
/db_xref="GeneID:852394"
CDS 436951..441315
/gene="VPS15"
/locus_tag="YBR097W"
/gene_synonym="GRD8; VAC4; VPL19; VPS40"
/EC_number="2.7.11.1"
/note="Myristoylated serine/threonine protein kinase
involved in vacuolar protein sorting; functions as a
membrane-associated complex with Vps34p; active form
recruits Vps34p to the Golgi membrane; interacts with the
GDP-bound form of Gpa1p"
/codon_start=1
/product="Vps15p"
/protein_id="NP_009655.2"
/db_xref="GI:330443447"
/db_xref="SGD:S000000301"
/db_xref="GeneID:852394"
/translation="MGAQLSLVVQASPSIAIFSYIDVLEEVHYVSQLNSSRFLKTCKA
LDPNGEIVIKVFIKPKDQYSLRPFLQRIRAQSFKLGQLPHVLNYSKLIETNRAGYMIR
QHLKNNLYDRLSLRPYLQDIELKFIAFQLLNALKDIHNLNIVHGDIKTENILVTSWNW
CILTDFAAFIKPVYLPEDNPGEFLFYFDTSKRRTCYLAPERFNSKLYQDGKSNNGRLT
KEMDIFSLGCVIAEIFAEGRPIFNLSQLFKYKSNSYDVNREFLMEEMNSTDLRNLVLD
MIQLDPSKRLSCDELLNKYRGIFFPDYFYTFIYDYFRNLVTMTTSTPISDNTCTNSTL
EDNVKLLDETTEKIYRDFSQICHCLDFPLIKDGGEIGSDPPILESYKIEIEISRFLNT
NLYFPQNYHLVLQQFTKVSEKIKSVKEECALLFISYLSHSIRSIVSTATKLKNLELLA
VFAQFVSDENKIDRVVPYFVCCFEDSDQDVQALSLLTLIQVLTSVRKLNQLNENIFVD
YLLPRLKRLLISNRQNTNYLRIVFANCLSDLAIIINRFQEFTFAQHCNDNSMDNNTEI
MESSTKYSAKLIQSVEDLTVSFLTDNDTYVKMALLQNILPLCKFFGRERTNDIILSHL
ITYLNDKDPALRVSLIQTISGISILLGTVTLEQYILPLLIQTITDSEELVVISVLQSL
KSLFKTGLIRKKYYIDISKTTSPLLLHPNNWIRQFTLMIIIEIINKLSKAEVYCILYP
IIRPFFEFDVEFNFKSMISCCKQPVSRSVYNLLCSWSVRASKSLFWKKIITNHVDSFG
NNRIEFITKNYSSKNYGFNKRDTKSSSSLKGIKTSSTVYSHDNKEIPLTAEDRNWIDK
FHIIGLTEKDIWKIVALRGYVIRTARVMAANPDFPYNNSNYRPLVQNSPPNLNLTNIM
PRNIFFDVEFAEESTSEGQDSNLENQQIYKYDESEKDSNKLNINGSKQLSTVMDINGS
LIFKNKSIATTTSNLKNVFVQLEPTSYHMHSPNHGLKDNANVKPERKVVVSNSYEGDV
ESIEKFLSTFKILPPLRDYKEFGPIQEIVRSPNMGNLRGKLIATLMENEPNSITSSAV
SPGETPYLITGSDQGVIKIWNLKEIIVGEVYSSSLTYDCSSTVTQITMIPNFDAFAVS
SKDGQIIVLKVNHYQQESEVKFLNCECIRKINLKNFGKNEYAVRMRAFVNEEKSLLVA
LTNLSRVIIFDIRTLERLQIIENSPRHGAVSSICIDEECCVLILGTTRGIIDIWDIRF
NVLIRSWSFGDHAPITHVEVCQFYGKNSVIVVGGSSKTFLTIWNFVKGHCQYAFINSD
EQPSMEHFLPIEKGLEELNFCGIRSLNALSTISVSNDKILLTDEATSSIVMFSLNELS
SSKAVISPSRFSDVFIPTQVTANLTMLLRKMKRTSTHSVDDSLYHHDIINSISTCEVD
ETPLLVACDNSGLIGIFQ"
gene 441515..443590
/gene="MMS4"
/locus_tag="YBR098W"
/gene_synonym="SLX2; YBR100W"
/db_xref="GeneID:852395"
mRNA 441515..443590
/gene="MMS4"
/locus_tag="YBR098W"
/gene_synonym="SLX2; YBR100W"
/product="Mms4p"
/transcript_id="NM_001178446.1"
/db_xref="GI:296142767"
/db_xref="GeneID:852395"
CDS 441515..443590
/gene="MMS4"
/locus_tag="YBR098W"
/gene_synonym="SLX2; YBR100W"
/note="Subunit of the structure-specific Mms4p-Mus81p
endonuclease that cleaves branched DNA; involved in
recombination, DNA repair, and joint molecule
formation/resolution during meiotic recombination;
phosphorylation of the non-catalytic subunit Mms4p by
Cdc28p and Cdcp during mitotic cell cycle activates the
function of Mms4p-Mus81p"
/codon_start=1
/product="Mms4p"
/protein_id="NP_009656.2"
/db_xref="GI:27808702"
/db_xref="SGD:S000000302"
/db_xref="GeneID:852395"
/translation="MSQIVDFVEDKDSRNDASIQIIDGPSNVEIIALSESMDQDECKR
AHVSSAEMIPSSPQRKSVSNDVENVDLNKSIELSAPFFQDISISKLDDFSTTVNSIID
SSLRNENNAKGNAKKLLDDLISDEWSADLESSGKKHNKSQYNLRDIAEKWGVQSLKNP
EPIAVDCEYKTQGIGKTNSDISDSPKSQIGAADILFDFPLSPVKHENPTEEKHNSIAN
ENSSPDNSLKPAGKQNHGEDGTSMAKRVYNKGEDEQEHLPKGKKRTIALSRTLINSTK
LPDTVELNLSKFLDSSDSITTDVLSTPAKGSNIVRTGSQPIFSNANCFQEAKRSKTLT
AEDPKCTKNTAREVSQLENYIAYGQYYTREDSKNKIRHLLKENKNAFKRVNQIYRDNI
KARSQMIIEFSPSLLQLFKKGDSDLQQQLAPAVVQSSYNDSMPLLRFLRKCDSIYDFS
NDFYYPCDPKIVEENVLILYYDAQEFFEQYTSQKKELYRKIRFFSKNGKHVILILSDI
NKLKRAIFQLENEKYKARVEQRLSGTEEALRPRSKKSSQVGKLGIKKFDLEQRLRFID
REWHVKIHTVNSHMEFINSLPNLVSLIGKQRMDPAIRYMKYAHLNVKSAQDSTETLKK
TFHQIGRMPEMKANNVVSLYPSFQSLLEDIEKGRLQSDNEGKYLMTEAVEKRLYKLFT
CTDPNDTIE"
gene complement(443821..444693)
/gene="FES1"
/locus_tag="YBR101C"
/db_xref="GeneID:852397"
mRNA complement(443821..444693)
/gene="FES1"
/locus_tag="YBR101C"
/product="Fes1p"
/transcript_id="NM_001178449.3"
/db_xref="GI:398364782"
/db_xref="GeneID:852397"
CDS complement(443821..444693)
/gene="FES1"
/locus_tag="YBR101C"
/note="Hsp70 (Ssa1p) nucleotide exchange factor; cytosolic
homolog of Sil1p, which is the nucleotide exchange factor
for BiP (Kar2p) in the endoplasmic reticulum; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="Fes1p"
/protein_id="NP_009659.3"
/db_xref="GI:398364783"
/db_xref="SGD:S000000305"
/db_xref="GeneID:852397"
/translation="MEKLLQWSIANSQGDKEAMARAGQPDPKLLQQLFGGGGPDDPTL
MKESMAVIMNPEVDLETKLVAFDNFEMLIENLDNANNIENLKLWEPLLDVLVQTKDEE
LRAAALSIIGTAVQNNLDSQNNFMKYDNGLRSLIEIASDKTKPLDVRTKAFYALSNLI
RNHKDISEKFFKLNGLDCIAPVLSDNTAKPKLKMRAIALLTAYLSSVKIDENIISVLR
KDGVIESTIECLSDESNLNIIDRVLSFLSHLISSGIKFNEQELHKLNEGYKHIEPLKD
RLNEDDYLAVKYVL"
gene complement(445062..447323)
/gene="EXO84"
/locus_tag="YBR102C"
/gene_synonym="USA3"
/db_xref="GeneID:852398"
mRNA complement(445062..447323)
/gene="EXO84"
/locus_tag="YBR102C"
/gene_synonym="USA3"
/product="Exo84p"
/transcript_id="NM_001178450.1"
/db_xref="GI:296142769"
/db_xref="GeneID:852398"
CDS complement(445062..447323)
/gene="EXO84"
/locus_tag="YBR102C"
/gene_synonym="USA3"
/note="Essential protein with dual roles in spliceosome
assembly and exocytosis; the exocyst complex (Sec3p,
Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p)
mediates polarized targeting of secretory vesicles to
active sites of exocytosis"
/codon_start=1
/product="Exo84p"
/protein_id="NP_009660.1"
/db_xref="GI:6319578"
/db_xref="SGD:S000000306"
/db_xref="GeneID:852398"
/translation="MVEFSLKKARNNWKHVKKSASSPAKQKTPPSPAKPKQKTKKNPY
SDLKDPATSYTLPTINARERSRVATSMQRRLSIHNTNYAPPTLDYSMPLPDMPNMIVP
NDNVDSSHNNSSFTTENESVSSKGPSNSLNLSTADLSLNDSSYNKVPARSAMRNTVNP
SGSNDPFNNSTSLRKMLANPHFNAKDFVHDKLGNASAITIDKFTSNLTDLSIQVQEEV
KLNINKSYNEIMTVNNDLNVAMLELKRVRANINDLNEVLDQCTKIAEKRLQLQDQIDQ
ERQGNFNNVESHSNSPALLPPLKAGQNGNLMRRDRSSVLILEKFWDTELDQLFKNVEG
AQKFINSTKGRHILMNSANWMELNTTTGKPLQMVQIFILNDLVLIADKSRDKQNDFIV
SQCYPLKDVTVTQEEFSTKRLLFKFSNSNSSLYECRDADECSRLLDVIRKAKDDLCDI
FHVEEENSKRIRESFRYLQSTQQTPGRENNRSPNKNKRRSMGGSITPGRNVTGAMDQY
LLQNLTLSMHSRPRSRDMSSTAQRLKFLDEGVEEIDIELARLRFESAVETLLDIESQL
EDLSERISDEELMLLNLISLKIEQRREAISSKLSQSILSSNEIVHLKSGTENMIKLGL
PEQALDLFLQNRSNFIQDLILQIGSVDNPTNYLTQLAVIRFQTIKKTVEDFQDIFKEL
GAKISSILVDWCSDEVDNHFKLIDKQLLNDEMLSPGSIKSSRKQIDGLKAVGLDFVYK
LDEFIKKNSDKIR"
gene 447709..449316
/gene="SIF2"
/locus_tag="YBR103W"
/gene_synonym="EMB1"
/db_xref="GeneID:852399"
mRNA 447709..449316
/gene="SIF2"
/locus_tag="YBR103W"
/gene_synonym="EMB1"
/product="Sif2p"
/transcript_id="NM_001178451.1"
/db_xref="GI:296142770"
/db_xref="GeneID:852399"
CDS 447709..449316
/gene="SIF2"
/locus_tag="YBR103W"
/gene_synonym="EMB1"
/note="WD40 repeat-containing subunit of the Set3C histone
deacetylase complex, which represses early/middle
sporulation genes; antagonizes telomeric silencing; binds
specifically to the Sir4p N-terminus"
/codon_start=1
/product="Sif2p"
/protein_id="NP_009661.1"
/db_xref="GI:6319579"
/db_xref="SGD:S000000307"
/db_xref="GeneID:852399"
/translation="MSITSEELNYLIWRYCQEMGHEVSALALQDETRVLEFDEKYKEH
IPLGTLVNLVQRGILYTESELMVDSKGDISALNEHHLSEDFNLVQALQIDKEKFPEIS
SEGRFTLETNSESNKAGEDGASTVERETQEDDTNSIDSSDDLDGFVKILKEIVKLDNI
VSSTWNPLDESILAYGEKNSVARLARIVETDQEGKKYWKLTIIAELRHPFALSASSGK
TTNQVTCLAWSHDGNSIVTGVENGELRLWNKTGALLNVLNFHRAPIVSVKWNKDGTHI
ISMDVENVTILWNVISGTVMQHFELKETGGSSINAENHSGDGSLGVDVEWVDDDKFVI
PGPKGAIFVYQITEKTPTGKLIGHHGPISVLEFNDTNKLLLSASDDGTLRIWHGGNGN
SQNCFYGHSQSIVSASWVGDDKVISCSMDGSVRLWSLKQNTLLALSIVDGVPIFAGRI
SQDGQKYAVAFMDGQVNVYDLKKLNSKSRSLYGNRDGILNPLPIPLYASYQSSQDNDY
IFDLSWNCAGNKISVAYSLQEGSVVAI"
gene 449667..450656
/gene="YMC2"
/locus_tag="YBR104W"
/db_xref="GeneID:852401"
mRNA 449667..450656
/gene="YMC2"
/locus_tag="YBR104W"
/product="Ymc2p"
/transcript_id="NM_001178452.3"
/db_xref="GI:398364796"
/db_xref="GeneID:852401"
CDS 449667..450656
/gene="YMC2"
/locus_tag="YBR104W"
/note="Mitochondrial protein, putative inner membrane
transporter with a role in oleate metabolism and glutamate
biosynthesis; member of the mitochondrial carrier (MCF)
family; has similarity with Ymc1p"
/codon_start=1
/product="Ymc2p"
/protein_id="NP_009662.3"
/db_xref="GI:398364797"
/db_xref="SGD:S000000308"
/db_xref="GeneID:852401"
/translation="MSEEFPTPQLLDELEDQQKVTTPNEKRELSSNRVLKDIFAGTIG
GIAQVLVGQPFDTTKVRLQTATTRTTTLEVLRNLVKNEGVFAFYKGALTPLLGVGICV
SVQFGVNEAMKRFFQNYNASKNPNMSSQDVDLSRSNTLPLSQYYVCGLTGGVVNSFLA
SPIEQIRIRLQTQTSNGGDREFKGPWDCIKKLKAQGGLMRGLFPTMIRAGHGLGTYFL
VYEALVAREIGTGLTRNEIPPWKLCLFGAFSGTMLWLTVYPLDVVKSIIQNDDLRKPK
YKNSISYVAKTIYAKEGIRAFFKGFGPTMVRSAPVNGATFLTFELVMRFLGEE"
gene complement(450881..451969)
/gene="VID24"
/locus_tag="YBR105C"
/gene_synonym="GID4"
/db_xref="GeneID:852402"
mRNA complement(450881..451969)
/gene="VID24"
/locus_tag="YBR105C"
/gene_synonym="GID4"
/product="glucose-induced degradation complex subunit
VID24"
/transcript_id="NM_001178453.1"
/db_xref="GI:296142772"
/db_xref="GeneID:852402"
CDS complement(450881..451969)
/gene="VID24"
/locus_tag="YBR105C"
/gene_synonym="GID4"
/note="GID Complex regulatory subunit; binds GID Complex
in response to glucose through interactions with complex
member Vid28p; regulates fructose-1,6-bisphosphatase
(FBPase) targeting to the vacuole; promotes
proteasome-dependent catabolite degradation of FBPase;
peripheral membrane protein located at Vid (vacuole import
and degradation) vesicles"
/codon_start=1
/product="glucose-induced degradation complex subunit
VID24"
/protein_id="NP_009663.1"
/db_xref="GI:6319581"
/db_xref="SGD:S000000309"
/db_xref="GeneID:852402"
/translation="MINNPKVDSVAEKPKAVTSKQSEQAASPEPTPAPPVSRNQYPIT
FNLTSTAPFHLHDRHRYLQEQDLYKCASRDSLSSLQQLAHTPNGSTRKKYIVEDQSPY
SSENPVIVTSSYNHTVCTNYLRPRMQFTGYQISGYKRYQVTVNLKTVDLPKKDCTSLS
PHLSGFLSIRGLTNQHPEISTYFEAYAVNHKELGFLSSSWKDEPVLNEFKATDQTDLE
HWINFPSFRQLFLMSQKNGLNSTDDNGTTNAAKKLPPQQLPTTPSADAGNISRIFSQE
KQFDNYLNERFIFMKWKEKFLVPDALLMEGVDGASYDGFYYIVHDQVTGNIQGFYYHQ
DAEKFQQLELVPSLKNKVESSDCSFEFA"
gene 452658..453224
/gene="PHO88"
/locus_tag="YBR106W"
/db_xref="GeneID:852403"
mRNA 452658..453224
/gene="PHO88"
/locus_tag="YBR106W"
/product="Pho88p"
/transcript_id="NM_001178454.1"
/db_xref="GI:296142773"
/db_xref="GeneID:852403"
CDS 452658..453224
/gene="PHO88"
/locus_tag="YBR106W"
/note="Probable membrane protein, involved in phosphate
transport; pho88 pho86 double null mutant exhibits
enhanced synthesis of repressible acid phosphatase at high
inorganic phosphate concentrations"
/codon_start=1
/product="Pho88p"
/protein_id="NP_009664.1"
/db_xref="GI:6319582"
/db_xref="SGD:S000000310"
/db_xref="GeneID:852403"
/translation="MNPQVSNIIIMLVMMQLSRRIDMEDPTIIMYIRILYCSSIGISW
IIYQMARKRIVAKNDMTTMKYVEPGNAMSGEGEKLQVTTVRDYDLKEIDSAIKSIYTG
MAMMGFMHLYLKYTNPLFMQSISPVKSALEHNEVKIHLFGKPATGDLKRPFKAPSLFG
GMGQTGPKTDKKSIEEAERAGNAGVKAE"
gene complement(453793..454530)
/gene="IML3"
/locus_tag="YBR107C"
/gene_synonym="MCM19"
/db_xref="GeneID:852404"
mRNA complement(453793..454530)
/gene="IML3"
/locus_tag="YBR107C"
/gene_synonym="MCM19"
/product="Iml3p"
/transcript_id="NM_001178455.3"
/db_xref="GI:398364814"
/db_xref="GeneID:852404"
CDS complement(453793..454530)
/gene="IML3"
/locus_tag="YBR107C"
/gene_synonym="MCM19"
/note="Outer kinetochore protein and component of the
Ctf19 complex; involved in the establishment of
pericentromeric cohesion during mitosis; prevents
non-disjunction of sister chromatids during meiosis II;
required for localization of Sgo1p to pericentric sites
during meiosis I; orthologous to human centromere
constitutive-associated network (CCAN) subunit CENP-L and
fission yeast fta1"
/codon_start=1
/product="Iml3p"
/protein_id="NP_009665.3"
/db_xref="GI:398364815"
/db_xref="SGD:S000000311"
/db_xref="GeneID:852404"
/translation="MPYTWKFLGISKQLSLENGIAKLNQLLNLEVDLDIQTIRVPSDP
DGGTAADEYIRYEMRLDISNLDEGTYSKFIFLGNSKMEVPMFLCYCGTDNRNEVVLQW
LKAEYGVIMWPIKFEQKTMIKLADASIVHVTKENIEQITWFSSKLYFEPETQDKNLRQ
FSIEIPRESCEGLALGYGNTMHPYNDAIVPYIYNETGMAVERLPLTSVILAGHTKIMR
ESIVTSTRSLRNRVLAVVLQSIQFTSE"
gene 454822..457665
/gene="AIM3"
/locus_tag="YBR108W"
/db_xref="GeneID:852405"
mRNA 454822..457665
/gene="AIM3"
/locus_tag="YBR108W"
/product="Aim3p"
/transcript_id="NM_001178456.2"
/db_xref="GI:330443448"
/db_xref="GeneID:852405"
CDS 454822..457665
/gene="AIM3"
/locus_tag="YBR108W"
/note="Protein interacting with Rvs167p; null mutant is
viable and displays elevated frequency of mitochondrial
genome loss"
/codon_start=1
/product="Aim3p"
/protein_id="NP_009666.3"
/db_xref="GI:330443449"
/db_xref="SGD:S000000312"
/db_xref="GeneID:852405"
/translation="MGFWENNKDSITSGLKSAGKYGYQGTKYVAKTGYKASKKHYNNS
KARRERKSGKKNSSDEEYDSEDEMEYERKPTDIRSLKDPKSFPPPPLKPGQKTYTGQQ
QQQMPNGQASYAFQGAYQGQPGAGSTEQSQYAQPQYNQYPQQQLQQGVMPQQQQLQQG
VVPQQPPIYGEQVPPYGSNSNATSYQSLPQQNQPQNAIPSQVSLNSASQQSTGFVSQN
LQYGTQSSNPAPSPSFQNGLQCHQQPQYVSHGSTNLGQSQFPSGQQQQPTTQFGQQVL
PSPAQPQQQQQGQPLPPPRGQVILPAPGEPLSNGFGQQQQQQQQQQQPLNQNNALLPQ
MNVEGVSGMAAVQPVYGQAMSSTTNMQDSNPSYGASPMQGQPPVGGQPPVPVRMQPQP
PQPMQQGNIYPIEPSLDSTGSTPHFEVTPFDPDAPAPKPKIDIPTVDVSSLPPPPTHR
DRGAVVHQEPAPSGKIQPNTTSSAASLPAKHSRTTTADNERNSGNKENDESTSKSSIL
GHYDVDVNIMPPPKPFRHGLDSVPSEHTTKNAPERAVPILPPRNNVEPPPPPSRGNFE
RTESVLSTNAANVQEDPISNFLPPPKPFRHTETKQNQNSKASPVEMKGEVLPGHPSEE
DRNVEPSLVPQSKPQSQSQFRRAHMETQPIQNFQPPPKPFRRSQSSNSSDSSYTIDGP
EANHGRGRGRIAKHHDGDEYNPKSENSTENGRLGDAPNSFIRKRAPTPPAPSRSEKLH
EGTITSEVDSSKDANKYEKSIPPVTSSIQAQQSTKKAPPPVVKPKPRNFSLKANEYPK
ELTREATGQDEVLNSITNELSHIKLRKTNVNLEKLGGSKKVKDSSPVPSDLDEKYVSA
SGSITPPRPPPSRSSPKKVPPVVPKKNDNLKKKPPVVPKKKPLLKSLEPRPIEMERAY
SGDISAADDNLNPFERYKRNVVPQEDDRLHKLK"
gene complement(457919..458362)
/gene="CMD1"
/locus_tag="YBR109C"
/db_xref="GeneID:852406"
mRNA complement(457919..458362)
/gene="CMD1"
/locus_tag="YBR109C"
/product="Cmd1p"
/transcript_id="NM_001178457.1"
/db_xref="GI:296142776"
/db_xref="GeneID:852406"
CDS complement(457919..458362)
/gene="CMD1"
/locus_tag="YBR109C"
/note="Calmodulin; Ca++ binding protein that regulates
Ca++ independent processes (mitosis, bud growth, actin
organization, endocytosis, etc.) and Ca++ dependent
processes (stress-activated pathways), targets include
Nuf1p, Myo2p and calcineurin"
/codon_start=1
/product="Cmd1p"
/protein_id="NP_009667.1"
/db_xref="GI:6319585"
/db_xref="SGD:S000000313"
/db_xref="GeneID:852406"
/translation="MSSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSP
SEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLIS
AAELKHVLTSIGEKLTDAEVDDMLREVSDGSGEINIQQFAALLSK"
gene 458872..460221
/gene="ALG1"
/locus_tag="YBR110W"
/db_xref="GeneID:852407"
mRNA 458872..460221
/gene="ALG1"
/locus_tag="YBR110W"
/product="chitobiosyldiphosphodolichol beta-1,4
mannosyltransferase"
/transcript_id="NM_001178458.3"
/db_xref="GI:398364840"
/db_xref="GeneID:852407"
CDS 458872..460221
/gene="ALG1"
/locus_tag="YBR110W"
/EC_number="2.4.1.142"
/note="Mannosyltransferase, involved in asparagine-linked
glycosylation in the endoplasmic reticulum (ER); essential
for viability, mutation is functionally complemented by
human ortholog"
/codon_start=1
/product="chitobiosyldiphosphodolichol beta-1,4
mannosyltransferase"
/protein_id="NP_009668.3"
/db_xref="GI:398364841"
/db_xref="SGD:S000000314"
/db_xref="GeneID:852407"
/translation="MFLEIPRWLLALIILYLSIPLVVYYVIPYLFYGNKSTKKRIIIF
VLGDVGHSPRICYHAISFSKLGWQVELCGYVEDTLPKIISSDPNITVHHMSNLKRKGG
GTSVIFMVKKVLFQVLSIFKLLWELRGSDYILVQNPPSIPILPIAVLYKLTGCKLIID
WHNLAYSILQLKFKGNFYHPLVLISYMVEMIFSKFADYNLTVTEAMRKYLIQSFHLNP
KRCAVLYDRPASQFQPLAGDISRQKALTTKAFIKNYIRDDFDTEKGDKIIVTSTSFTP
DEDIGILLGALKIYENSYVKFDSSLPKILCFITGKGPLKEKYMKQVEEYDWKRCQIEF
VWLSAEDYPKLLQLCDYGVSLHTSSSGLDLPMKILDMFGSGLPVIAMNYPVLDELVQH
NVNGLKFVDRRELHESLIFAMKDADLYQKLKKNVTQEAENRWQSNWERTMRDLKLIH"
gene complement(461178..461873)
/gene="YSA1"
/locus_tag="YBR111C"
/gene_synonym="RMA2"
/db_xref="GeneID:852408"
mRNA complement(461178..461873)
/gene="YSA1"
/locus_tag="YBR111C"
/gene_synonym="RMA2"
/product="Ysa1p"
/transcript_id="NM_001178459.1"
/db_xref="GI:296142778"
/db_xref="GeneID:852408"
CDS complement(461178..461873)
/gene="YSA1"
/locus_tag="YBR111C"
/gene_synonym="RMA2"
/EC_number="3.6.1.13"
/note="Nudix hydrolase family member with ADP-ribose
pyrophosphatase activity; shown to metabolize
O-acetyl-ADP-ribose to AMP and acetylated ribose
5'-phosphate"
/codon_start=1
/product="Ysa1p"
/protein_id="NP_009669.1"
/db_xref="GI:6319587"
/db_xref="SGD:S000000315"
/db_xref="GeneID:852408"
/translation="MFLRNVRVISLNSRRLFRTMSTVKGKPEDAKIIEARHVKETSDC
KWIGLQKIIYKDPNGKEREWDSAVRTTRSSGGVDGIGILTILKYKDGKPDEILLQKQF
RPPVEGVCIEMPAGLIDAGEDIDTAALRELKEETGYSGKIISKSPTVFNDPGFTNTNL
CLVTVEVDMSLPENQKPVTQLEDNEFIECFSVELHKFPDEMVKLDQQGYKLDARVQNV
AQGILMAKQYHIK"
gene 462139..462579
/gene="SUS1"
/locus_tag="YBR111W-A"
/db_xref="GeneID:1466445"
mRNA join(462139..462209,462290..462429,462500..462579)
/gene="SUS1"
/locus_tag="YBR111W-A"
/product="Sus1p"
/transcript_id="NM_001184520.1"
/db_xref="GI:296142779"
/db_xref="GeneID:1466445"
CDS join(462139..462209,462290..462429,462500..462579)
/gene="SUS1"
/locus_tag="YBR111W-A"
/note="Component of both the SAGA histone acetylase and
TREX-2 complexes; interacts with RNA polymerase II;
involved in mRNA export coupled transcription activation
and elongation; involved in post-transcriptional tethering
of active genes to the nuclear periphery and to
non-nascent mRNP"
/codon_start=1
/product="Sus1p"
/protein_id="NP_878049.2"
/db_xref="GI:41629677"
/db_xref="SGD:S000028510"
/db_xref="GeneID:1466445"
/translation="MTMDTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKD
LTKSEMNINESTNFTQILSTVEPKALEMVSDSTRETVLKQIREFLEEIVDTQ"
gene complement(462870..465770)
/gene="CYC8"
/locus_tag="YBR112C"
/gene_synonym="CRT8; SSN6"
/db_xref="GeneID:852410"
mRNA complement(462870..465770)
/gene="CYC8"
/locus_tag="YBR112C"
/gene_synonym="CRT8; SSN6"
/product="Cyc8p"
/transcript_id="NM_001178460.3"
/db_xref="GI:398364854"
/db_xref="GeneID:852410"
CDS complement(462870..465770)
/gene="CYC8"
/locus_tag="YBR112C"
/gene_synonym="CRT8; SSN6"
/note="General transcriptional co-repressor, acts together
with Tup1p; also acts as part of a transcriptional
co-activator complex that recruits the SWI/SNF and SAGA
complexes to promoters; can form the prion [OCT+]"
/codon_start=1
/product="Cyc8p"
/protein_id="NP_009670.3"
/db_xref="GI:398364855"
/db_xref="SGD:S000000316"
/db_xref="GeneID:852410"
/translation="MNPGGEQTIMEQPAQQQQQQQQQQQQQQQQAAVPQQPLDPLTQS
TAETWLSIASLAETLGDGDRAAMAYDATLQFNPSSAKALTSLAHLYRSRDMFQRAAEL
YERALLVNPELSDVWATLGHCYLMLDDLQRAYNAYQQALYHLSNPNVPKLWHGIGILY
DRYGSLDYAEEAFAKVLELDPHFEKANEIYFRLGIIYKHQGKWSQALECFRYILPQPP
APLQEWDIWFQLGSVLESMGEWQGAKEAYEHVLAQNQHHAKVLQQLGCLYGMSNVQFY
DPQKALDYLLKSLEADPSDATTWYHLGRVHMIRTDYTAAYDAFQQAVNRDSRNPIFWC
SIGVLYYQISQYRDALDAYTRAIRLNPYISEVWYDLGTLYETCNNQLSDALDAYKQAA
RLDVNNVHIRERLEALTKQLENPGNINKSNGAPTNASPAPPPVILQPTLQPNDQGNPL
NTRISAQSANATASMVQQQHPAQQTPINSSATMYSNGASPQLQAQAQAQAQAQAQAQA
QAQAQAQAQAQAQAQAQAQAQAQAQAQAHAQAQAQAQAQAQAQAQAQAQQQQQQQQQQ
QQQQQQQQQQQQQQQQQQQQQLQPLPRQQLQQKGVSVQMLNPQQGQPYITQPTVIQAH
QLQPFSTQAMEHPQSSQLPPQQQQLQSVQHPQQLQGQPQAQAPQPLIQHNVEQNVLPQ
KRYMEGAIHTLVDAAVSSSTHTENNTKSPRQPTHAIPTQAPATGITNAEPQVKKQKLN
SPNSNINKLVNTATSIEENAKSEVSNQSPAVVESNTNNTSQEEKPVKANSIPSVIGAQ
EPPQEASPAEEATKAASVSPSTKPLNTEPESSSVQPTVSSESSTTKANDQSTAETIEL
STATVPAEASPVEDEVRQHSKEENGTTEASAPSTEEAEPAASRDAEKQQDETAATTIT
VIKPTLETMETVKEEAKMREEEQTSQEKSPQENTLPRENVVRQVEEDENYDD"
gene 467248..469620
/gene="RAD16"
/locus_tag="YBR114W"
/gene_synonym="PSO5"
/db_xref="GeneID:852411"
mRNA 467248..469620
/gene="RAD16"
/locus_tag="YBR114W"
/gene_synonym="PSO5"
/product="Rad16p"
/transcript_id="NM_001178462.1"
/db_xref="GI:296142781"
/db_xref="GeneID:852411"
CDS 467248..469620
/gene="RAD16"
/locus_tag="YBR114W"
/gene_synonym="PSO5"
/EC_number="3.6.1.-"
/note="Protein that recognizes and binds damaged DNA in an
ATP-dependent manner (with Rad7p) during nucleotide
excision repair; subunit of Nucleotide Excision Repair
Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase
complex"
/codon_start=1
/product="Rad16p"
/protein_id="NP_009672.1"
/db_xref="GI:6319590"
/db_xref="SGD:S000000318"
/db_xref="GeneID:852411"
/translation="MQEGGFIRRRRTRSTKKSVNYNELSDDDTAVKNSKTLQLKGNSE
NVNDSQDEEYRDDATLVKSPDDDDKDFIIDLTGSDKERTATDENTHAIKNDNDEIIEI
KEERDVSDDDEPLTKKRKTTARKKKKKTSTKKKSPKVTPYERNTLRLYEHHPELRNVF
TDLKNAPPYVPQRSKQPDGMTIKLLPFQLEGLHWLISQEESIYAGGVLADEMGMGKTI
QTIALLMNDLTKSPSLVVAPTVALMQWKNEIEQHTKGQLKIYIYHGASRTTDIKDLQG
YDVVLTTYAVLESVFRKQNYGFRRKNGLFKQPSVLHNIDFYRVILDEAHNIKDRQSNT
ARAVNNLKTQKRWCLSGTPLQNRIGEMYSLIRFLNINPFTKYFCTKCDCASKDWKFTD
RMHCDHCSHVIMQHTNFFNHFMLKNIQKFGVEGPGLESFNNIQTLLKNIMLRRTKVER
ADDLGLPPRIVTVRRDFFNEEEKDLYRSLYTDSKRKYNSFVEEGVVLNNYANIFTLIT
RMRQLADHPDLVLKRLNNFPGDDIGVVICQLCNDEAEEPIESKCHHKFCRLCIKEYVE
SFMENNNKLTCPVCHIGLSIDLSQPALEVDLDSFKKQSIVSRLNMSGKWQSSTKIEAL
VEELYKLRSNKRTIKSIVFSQFTSMLDLVEWRLKRAGFQTVKLQGSMSPTQRDETIKY
FMNNIQCEVFLVSLKAGGVALNLCEASQVFILDPWWNPSVEWQSGDRVHRIGQYRPVK
ITRFCIEDSIEARIIELQEKKANMIHATINQDEAAISRLTPADLQFLFNN"
gene complement(469748..473926)
/gene="LYS2"
/locus_tag="YBR115C"
/db_xref="GeneID:852412"
mRNA complement(469748..473926)
/gene="LYS2"
/locus_tag="YBR115C"
/product="L-aminoadipate-semialdehyde dehydrogenase"
/transcript_id="NM_001178463.1"
/db_xref="GI:296142782"
/db_xref="GeneID:852412"
CDS complement(469748..473926)
/gene="LYS2"
/locus_tag="YBR115C"
/EC_number="1.2.1.31"
/note="Alpha aminoadipate reductase, catalyzes the
reduction of alpha-aminoadipate to alpha-aminoadipate
6-semialdehyde, which is the fifth step in biosynthesis of
lysine; activation requires posttranslational
phosphopantetheinylation by Lys5p"
/codon_start=1
/product="L-aminoadipate-semialdehyde dehydrogenase"
/protein_id="NP_009673.1"
/db_xref="GI:6319591"
/db_xref="SGD:S000000319"
/db_xref="GeneID:852412"
/translation="MTNEKVWIEKLDNPTLSVLPHDFLRPQQEPYTKQATYSLQLPQL
DVPHDSFSNKYAVALSVWAALIYRVTGDDDIVLYIANNKILRFNIQPTWSFNELYSTI
NNELNKLNSIEANFSFDELAEKIQSCQDLERTPQLFRLAFLENQDFKLDEFKHHLVDF
ALNLDTSNNAHVLNLIYNSLLYSNERVTIVADQFTQYLTAALSDPSNCITKISLITAS
SKDSLPDPTKNLGWCDFVGCIHDIFQDNAEAFPERTCVVETPTLNSDKSRSFTYRDIN
RTSNIVAHYLIKTGIKRGDVVMIYSSRGVDLMVCVMGVLKAGATFSVIDPAYPPARQT
IYLGVAKPRGLIVIRAAGQLDQLVEDYINDELEIVSRINSIAIQENGTIEGGKLDNGE
DVLAPYDHYKDTRTGVVVGPDSNPTLSFTSGSEGIPKGVLGRHFSLAYYFNWMSKRFN
LTENDKFTMLSGIAHDPIQRDMFTPLFLGAQLYVPTQDDIGTPGRLAEWMSKYGCTVT
HLTPAMGQLLTAQATTPFPKLHHAFFVGDILTKRDCLRLQTLAENCRIVNMYGTTETQ
RAVSYFEVKSKNDDPNFLKKLKDVMPAGKGMLNVQLLVVNRNDRTQICGIGEIGEIYV
RAGGLAEGYRGLPELNKEKFVNNWFVEKDHWNYLDKDNGEPWRQFWLGPRDRLYRTGD
LGRYLPNGDCECCGRADDQVKIRGFRIELGEIDTHISQHPLVRENITLVRKNADNEPT
LITFMVPRFDKPDDLSKFQSDVPKEVETDPIVKGLIGYHLLSKDIRTFLKKRLASYAM
PSLIVVMDKLPLNPNGKVDKPKLQFPTPKQLNLVAENTVSETDDSQFTNVEREVRDLW
LSILPTKPASVSPDDSFFDLGGHSILATKMIFTLKKKLQVDLPLGTIFKYPTIKAFAA
EIDRIKSSGGSSQGEVVENVTANYAEDAKKLVETLPSSYPSREYFVEPNSAEGKTTIN
VFVTGVTGFLGSYILADLLGRSPKNYSFKVFAHVRAKDEEAAFARLQKAGITYGTWNE
KFASNIKVVLGDLSKSQFGLSDEKWMDLANTVDIIIHNGALVHWVYPYAKLRDPNVIS
TINVMSLAAVGKPKFFDFVSSTSTLDTEYYFNLSDKLVSEGKPGILESDDLMNSASGL
TGGYGQSKWAAEYIIRRAGERGLRGCIVRPGYVTGASANGSSNTDDFLLRFLKGSVQL
GKIPDIENSVNMVPVDHVARVVVATSLNPPKENELAVAQVTGHPRILFKDYLYTLHDY
GYDVEIESYSKWKKSLEASVIDRNEENALYPLLHMVLDNLPESTKAPELDDRNAVASL
KKDTAWTGVDWSNGIGVTPEEVGIYIAFLNKVGFLPPPTHNDKLPLPSIELTQAQISL
VASGAGARGSSAAA"
gene complement(474392..476437)
/gene="TKL2"
/locus_tag="YBR117C"
/db_xref="GeneID:852414"
mRNA complement(474392..476437)
/gene="TKL2"
/locus_tag="YBR117C"
/product="transketolase TKL2"
/transcript_id="NM_001178465.3"
/db_xref="GI:398364878"
/db_xref="GeneID:852414"
CDS complement(474392..476437)
/gene="TKL2"
/locus_tag="YBR117C"
/EC_number="2.2.1.1"
/note="Transketolase; catalyzes conversion of
xylulose-5-phosphate and ribose-5-phosphate to
sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate
in the pentose phosphate pathway; needed for synthesis of
aromatic amino acids; TKL2 has a paralog, TKL1, that arose
from the whole genome duplication"
/codon_start=1
/product="transketolase TKL2"
/protein_id="NP_009675.3"
/db_xref="GI:398364879"
/db_xref="SGD:S000000321"
/db_xref="GeneID:852414"
/translation="MAQFSDIDKLAVSTLRLLSVDQVESAQSGHPGAPLGLAPVAHVI
FKQLRCNPNNEHWINRDRFVLSNGHSCALLYSMLHLLGYDYSIEDLRQFRQVNSRTPG
HPEFHSAGVEITSGPLGQGISNAVGMAIAQANFAATYNEDGFPISDSYTFAIVGDGCL
QEGVSSETSSLAGHLQLGNLITFYDSNSISIDGKTSYSFDEDVLKRYEAYGWEVMEVD
KGDDDMESISSALEKAKLSKDKPTIIKVTTTIGFGSLQQGTAGVHGSALKADDVKQLK
KRWGFDPNKSFVVPQEVYDYYKKTVVEPGQKLNEEWDRMFEEYKTKFPEKGKELQRRL
NGELPEGWEKHLPKFTPDDDALATRKTSQQVLTNMVQVLPELIGGSADLTPSNLTRWE
GAVDFQPPITQLGNYAGRYIRYGVREHGMGAIMNGISAFGANYKPYGGTFLNFVSYAA
GAVRLAALSGNPVIWVATHDSIGLGEDGPTHQPIETLAHLRAIPNMHVWRPADGNETS
AAYYSAIKSGRTPSVVALSRQNLPQLEHSSFEKALKGGYVIHDVENPDIILVSTGSEV
SISIDAAKKLYDTKKIKARVVSLPDFYTFDRQSEEYRFSVLPDGVPIMSFEVLATSSW
GKYAHQSFGLDEFGRSGKGPEIYKLFDFTADGVASRAEKTINYYKGKQLLSPMGRAF"
gene 477671..479047
/gene="TEF2"
/locus_tag="YBR118W"
/db_xref="GeneID:852415"
mRNA 477671..479047
/gene="TEF2"
/locus_tag="YBR118W"
/product="Tef2p"
/transcript_id="NM_001178466.1"
/db_xref="GI:296142784"
/db_xref="GeneID:852415"
CDS 477671..479047
/gene="TEF2"
/locus_tag="YBR118W"
/note="Translational elongation factor EF-1 alpha; also
encoded by TEF1; functions in the binding reaction of
aminoacyl-tRNA (AA-tRNA) to ribosomes; may also have a
role in tRNA re-export from the nucleus"
/codon_start=1
/product="Tef2p"
/protein_id="NP_009676.1"
/db_xref="GI:6319594"
/db_xref="SGD:S000000322"
/db_xref="GeneID:852415"
/translation="MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEK
EAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNM
ITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKW
DESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKA
GVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVV
TFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKG
CASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFL
KSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVDKTEKAAKVTK
AAQKAAKK"
gene 479338..480323
/gene="MUD1"
/locus_tag="YBR119W"
/db_xref="GeneID:852416"
mRNA join(479338..479345,479435..480323)
/gene="MUD1"
/locus_tag="YBR119W"
/product="Mud1p"
/transcript_id="NM_001178467.1"
/db_xref="GI:296142785"
/db_xref="GeneID:852416"
CDS join(479338..479345,479435..480323)
/gene="MUD1"
/locus_tag="YBR119W"
/note="U1 snRNP A protein, homolog of human U1-A; involved
in nuclear mRNA splicing"
/codon_start=1
/product="Mud1p"
/protein_id="NP_009677.1"
/db_xref="GI:6319595"
/db_xref="SGD:S000000323"
/db_xref="GeneID:852416"
/translation="MSALYFQNLPSRPANKENYTRLLLKHINPNNKYAINPSLPLPHN
KLQISSQPLMLLDDQMGLLEVSISRSSKMTNQAFLTFVTQEEADRFLEKYTTTALKVQ
GRKVRMGKARTNSLLGLSIEMQKKKGNDETYNLDIKKVLKARKLKRKLRSDDICAKKF
RLKRQIRRLKHKLRSRKVEEAEIDRIVKEFETRRLENMKSQQENLKQSQKPLKRAKVS
NTMENPPNKVLLIQNLPSGTTEQLLSQILGNEALVEIRLVSVRNLAFVEYETVADATK
IKNQLGSTYKLQNNDVTIGFAK"
gene complement(480435..480923)
/gene="CBP6"
/locus_tag="YBR120C"
/db_xref="GeneID:852417"
mRNA complement(480435..480923)
/gene="CBP6"
/locus_tag="YBR120C"
/product="Cbp6p"
/transcript_id="NM_001178468.3"
/db_xref="GI:398364896"
/db_xref="GeneID:852417"
CDS complement(480435..480923)
/gene="CBP6"
/locus_tag="YBR120C"
/note="Mitochondrial protein required for translation of
the COB mRNA; forms a complex with Cbp3p that binds to mt
ribosomes near the polypeptide tunnel exit and promotes
efficient translation of the COB mRNA; Cbp3p-Cbp6p complex
also interacts with newly synthesized cytochrome b (Cobp)
and Cbp4p to promote assembly of Cobp into the cytochrome
bc1 complex"
/codon_start=1
/product="Cbp6p"
/protein_id="NP_009678.3"
/db_xref="GI:398364897"
/db_xref="SGD:S000000324"
/db_xref="GeneID:852417"
/translation="MSSSQVVRDSAKKLVNLLEKYPKDRIHHLVSFRDVQIARFRRVA
GLPNVDDKGKSIKEKKPSLDEIKSIINRTSGPLGLNKEMLTKIQNKMVDEKFTEESIN
EQIRALSTIMNNKFRNYYDIGDKLYKPAGNPQYYQRLINAVDGKKKESLFTAMRTVLF
GK"
gene complement(481364..483367)
/gene="GRS1"
/locus_tag="YBR121C"
/db_xref="GeneID:852418"
mRNA complement(481364..483367)
/gene="GRS1"
/locus_tag="YBR121C"
/product="glycine--tRNA ligase"
/transcript_id="NM_001178469.2"
/db_xref="GI:330443450"
/db_xref="GeneID:852418"
CDS complement(481364..483367)
/gene="GRS1"
/locus_tag="YBR121C"
/EC_number="6.1.1.14"
/note="Cytoplasmic and mitochondrial glycyl-tRNA synthase
that ligates glycine to the cognate anticodon bearing
tRNA; transcription termination factor that may interact
with the 3'-end of pre-mRNA to promote 3'-end formation"
/codon_start=1
/product="glycine--tRNA ligase"
/protein_id="NP_009679.2"
/db_xref="GI:330443451"
/db_xref="SGD:S000000325"
/db_xref="GeneID:852418"
/translation="MSVEDIKKARAAVPFNREQLESVLRGRFFYAPAFDLYGGVSGLY
DYGPPGCAFQNNIIDAWRKHFILEEDMLEVDCTMLTPYEVLKTSGHVDKFSDWMCRDL
KTGEIFRADHLVEEVLEARLKGDQEARGLVEDANAAAKDDAEKKKRKKKVKQIKAVKL
DDDVVKEYEEILAKIDGYSGPELGELMEKYDIGNPVTGETLESPRAFNLMFETAIGPS
GQLKGYLRPETAQGQFLNFNKLLEFNNSKTPFASASIGKSFRNEISPRAGLLRVREFL
MAEIEHFVDPLDKSHPKFNEIKDIKLSFLPRDVQEAGSTEPIVKTVGEAVASRMVDNE
TLGYFIARIYQFLMKIGVDESKLRFRQHMANEMAHYAADCWDGELKTSYGWIECVGCA
DRSAYDLTVHSKKTKEKLVVRQKLDNPIEVTKWEIDLTKKLFGPKFRKDAPKVESHLL
NMSQDDLASKAELLKANGKFTIKVDGVDGEVELDDKLVKIEQRTKVEHVREYVPSVIE
PSFGIGRIIYSVFEHSFWNRPEDNARSVLSFPPLVAPTKVLLVPLSNHKDLVPVTTEV
AKILRKSQIPFKIDDSGVSIGKRYARNDELGTPFGVTIDFESAKDHSVTLRERDSTKQ
VRGSVENVIKAIRDITYNGASWEEGTKDLTPFIAQAEAEAETD"
gene complement(483970..484503)
/gene="MRPL36"
/locus_tag="YBR122C"
/db_xref="GeneID:852419"
mRNA complement(483970..484503)
/gene="MRPL36"
/locus_tag="YBR122C"
/product="mitochondrial 54S ribosomal protein YmL36"
/transcript_id="NM_001178470.1"
/db_xref="GI:296142788"
/db_xref="GeneID:852419"
CDS complement(483970..484503)
/gene="MRPL36"
/locus_tag="YBR122C"
/note="Mitochondrial ribosomal protein of the large
subunit; overproduction suppresses mutations in the COX2
leader peptide-encoding region"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL36"
/protein_id="NP_009680.2"
/db_xref="GI:37362620"
/db_xref="SGD:S000000326"
/db_xref="GeneID:852419"
/translation="MLKSIFAKRFASTGSYPGSTRITLPRRPAKKIQLGKSRPAIYHQ
FNVKMELSDGSVVIRRSQYPKGEIRLIQDQRNNPLWNPSRDDLVVVDANSGGSLDRFN
KRYSSLFSVDSTTPNSSSETVELSEENKKKTQIKKEEKEDVSEKAFGMDDYLSLLDDS
EQQIKSGKLASKKRDKK"
gene complement(484742..486691)
/gene="TFC1"
/locus_tag="YBR123C"
/db_xref="GeneID:852421"
mRNA complement(484742..486691)
/gene="TFC1"
/locus_tag="YBR123C"
/product="Tfc1p"
/transcript_id="NM_001178471.3"
/db_xref="GI:398364920"
/db_xref="GeneID:852421"
CDS complement(484742..486691)
/gene="TFC1"
/locus_tag="YBR123C"
/note="One of six subunits of the RNA polymerase III
transcription initiation factor complex (TFIIIC); part of
the TauA globular domain of TFIIIC that binds DNA at the
BoxA promoter sites of tRNA and similar genes; human
homolog is TFIIIC-63"
/codon_start=1
/product="Tfc1p"
/protein_id="NP_009681.3"
/db_xref="GI:398364921"
/db_xref="SGD:S000000327"
/db_xref="GeneID:852421"
/translation="MPVEEPLATLSSIPDSSADQAPPLIADEFTLDLPRIPSLELPLN
VSTKHSSIQKAIKMCGGIEKVKEAFKEHGPIESQHGLQLYLNDDTDSDGSKSYFNEHP
VIGKRVPFRDESVILKVTMPKGTLSKNNNSVKDSIKSLKDSNKLRVTPVSIVDNTIKF
REMSDFQIKLDNVPSAREFKSSFGSLEWNNFKSFVNSVPDNDSQPQENIGNLILDRSV
KIPSTDFQLPPPPKLSMVGFPLLYKYKANPFAKKKKNGVTEVKGTYIKNYQLFVHDLS
DKTVIPSQAHEQVLYDFEVAKKTKVYPGTKSDSKFYESLEECLKILRELFARRPIWVK
RHLDGIVPKKIHHTMKIALALISYRFTMGPWRNTYIKFGIDPRSSVEYAQYQTEYFKI
ERKLLSSPIVKKNVPKPPPLVFESDTPGGIDSRFKFDGKRIPWYLMLQIDLLIGEPNI
AEVFHNVEYLDKANELTGWFKELDLVKIRRIVKYELGCMVQGNYEYNKYKLKYFKTML
FVKESMVPENKNSEEGMGVNTNKDADGDINMDAGSQMSSNAIEEDKGIAAGDDFDDNG
AITEEPDDAALENEEMDTDQNLKVPASIDDDVDDVDADEEEQESFDVKTASFQDIINK
IAKLDPKTAETMKSELKGFVDEVDL"
rep_origin 486707..486954
/note="ARS216;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118350"
gene complement(487199..488380)
/gene="PTC4"
/locus_tag="YBR125C"
/gene_synonym="GCT1"
/db_xref="GeneID:852422"
mRNA complement(487199..488380)
/gene="PTC4"
/locus_tag="YBR125C"
/gene_synonym="GCT1"
/product="Ptc4p"
/transcript_id="NM_001178473.1"
/db_xref="GI:296142790"
/db_xref="GeneID:852422"
CDS complement(487199..488380)
/gene="PTC4"
/locus_tag="YBR125C"
/gene_synonym="GCT1"
/EC_number="3.1.3.16"
/note="Cytoplasmic type 2C protein phosphatase (PP2C);
identified as a high-copy number suppressor of cnb1 mpk1
synthetic lethality; overexpression decreases
high-osmolarity induced Hog1p phosphorylation and kinase
activity"
/codon_start=1
/product="Ptc4p"
/protein_id="NP_009683.1"
/db_xref="GI:6319601"
/db_xref="SGD:S000000329"
/db_xref="GeneID:852422"
/translation="MGQLLSHPLTEKTIEYNEYKNNQASTGIVPRFYNCVGSMQGYRL
TQEDAHLIRNENSVVYVRFFNPFIDKYETLSLNVFAVFDGHGGDDCSKFLSGGRHHRD
GNGSSNGNGEPNAGLIKWIAYSFENHHYTSTTNNDSSKFKRSFNTLEGLVSQIFKDAF
ILQDEELYRHFANSSCGSTAVVACIINEESLYVANCGDSRCILSSKSNGIKTMSFDHK
PQHIGELIRINDNGGTVSLGRVGGVLALSRAFSDFQFKRGVTYPHRRTKLTNITQNLT
YGTPPQEAQVTVEPDVLMHKIDYSKDEFLVLACDGIWDIYNNKQLIHFIKYHLVSGTK
LDTIITKLLDHGIAQANSNTGVGFDNMTAIIVVLNRKGETLQDWFNKMKTRLERERGL
V"
gene complement(488905..490392)
/gene="TPS1"
/locus_tag="YBR126C"
/gene_synonym="BYP1; CIF1; FDP1; GGS1; GLC6; TSS1"
/db_xref="GeneID:852423"
mRNA complement(488905..490392)
/gene="TPS1"
/locus_tag="YBR126C"
/gene_synonym="BYP1; CIF1; FDP1; GGS1; GLC6; TSS1"
/product="alpha,alpha-trehalose-phosphate synthase
(UDP-forming) TPS1"
/transcript_id="NM_001178474.1"
/db_xref="GI:296142791"
/db_xref="GeneID:852423"
CDS complement(488905..490392)
/gene="TPS1"
/locus_tag="YBR126C"
/gene_synonym="BYP1; CIF1; FDP1; GGS1; GLC6; TSS1"
/EC_number="2.4.1.15"
/note="Synthase subunit of trehalose-6-P
synthase/phosphatase complex; synthesizes the storage
carbohydrate trehalose; also found in a monomeric form;
expression is induced by the stress response and repressed
by the Ras-cAMP pathway; protein abundance increases in
response to DNA replication stress and in response to
prolonged exposure to boric acid"
/codon_start=1
/product="alpha,alpha-trehalose-phosphate synthase
(UDP-forming) TPS1"
/protein_id="NP_009684.1"
/db_xref="GI:6319602"
/db_xref="SGD:S000000330"
/db_xref="GeneID:852423"
/translation="MTTDNAKAQLTSSSGGNIIVVSNRLPVTITKNSSTGQYEYAMSS
GGLVTALEGLKKTYTFKWFGWPGLEIPDDEKDQVRKDLLEKFNAVPIFLSDEIADLHY
NGFSNSILWPLFHYHPGEINFDENAWLAYNEANQTFTNEIAKTMNHNDLIWVHDYHLM
LVPEMLRVKIHEKQLQNVKVGWFLHTPFPSSEIYRILPVRQEILKGVLSCDLVGFHTY
DYARHFLSSVQRVLNVNTLPNGVEYQGRFVNVGAFPIGIDVDKFTDGLKKESVQKRIQ
QLKETFKGCKIIVGVDRLDYIKGVPQKLHAMEVFLNEHPEWRGKVVLVQVAVPSRGDV
EEYQYLRSVVNELVGRINGQFGTVEFVPIHFMHKSIPFEELISLYAVSDVCLVSSTRD
GMNLVSYEYIACQEEKKGSLILSEFTGAAQSLNGAIIVNPWNTDDLSDAINEALTLPD
VKKEVNWEKLYKYISKYTSAFWGENFVHELYSTSSSSTSSSATKN"
gene 490850..491056
/locus_tag="YBR126W-A"
/db_xref="GeneID:13393614"
mRNA 490850..491056
/locus_tag="YBR126W-A"
/product="hypothetical protein"
/transcript_id="NM_001270740.1"
/db_xref="GI:398364944"
/db_xref="GeneID:13393614"
CDS 490850..491056
/locus_tag="YBR126W-A"
/note="hypothetical protein; identified by gene-trapping,
microarray analysis, and genome-wide homology searches;
mRNA identified as translated by ribosome profiling data;
partially overlaps the dubious ORF YBR126W-B"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001257669.1"
/db_xref="GI:398364945"
/db_xref="SGD:S000028600"
/db_xref="GeneID:13393614"
/translation="MAITPDKQKKEQQHQPQNGPLDYAHICKCIAMFFVVAGVVLMFF
ETGLDPEQKEQIKRLHQLDGIPHA"
gene complement(491269..492822)
/gene="VMA2"
/locus_tag="YBR127C"
/gene_synonym="VAT2"
/db_xref="GeneID:852424"
mRNA complement(491269..492822)
/gene="VMA2"
/locus_tag="YBR127C"
/gene_synonym="VAT2"
/product="Vma2p"
/transcript_id="NM_001178475.3"
/db_xref="GI:398364950"
/db_xref="GeneID:852424"
CDS complement(491269..492822)
/gene="VMA2"
/locus_tag="YBR127C"
/gene_synonym="VAT2"
/EC_number="3.6.3.14"
/note="Subunit B of the eight-subunit V1 peripheral
membrane domain of the vacuolar H+-ATPase (V-ATPase), an
electrogenic proton pump found throughout the endomembrane
system; contains nucleotide binding sites; also detected
in the cytoplasm; protein abundance increases in response
to DNA replication stress"
/codon_start=1
/product="Vma2p"
/protein_id="NP_009685.3"
/db_xref="GI:398364951"
/db_xref="SGD:S000000331"
/db_xref="GeneID:852424"
/translation="MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKV
KFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRI
PVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDT
MNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVN
LETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLT
ILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPI
LTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMT
RKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYE
DRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDRARDDADEDEEDPDTRSSGKKK
DASQEESLI"
gene complement(493081..494115)
/gene="ATG14"
/locus_tag="YBR128C"
/gene_synonym="APG14; CVT12"
/db_xref="GeneID:852425"
mRNA complement(493081..494115)
/gene="ATG14"
/locus_tag="YBR128C"
/gene_synonym="APG14; CVT12"
/product="Atg14p"
/transcript_id="NM_001178476.1"
/db_xref="GI:296142793"
/db_xref="GeneID:852425"
CDS complement(493081..494115)
/gene="ATG14"
/locus_tag="YBR128C"
/gene_synonym="APG14; CVT12"
/note="Autophagy-specific subunit of phosphatidylinositol
3-kinase complex I (with Vps34/15/30p); Atg14p targets
complex I to the phagophore assembly site (PAS); required
for localizing additional ATG proteins to the PAS; homolog
of human Barkor"
/codon_start=1
/product="Atg14p"
/protein_id="NP_009686.1"
/db_xref="GI:6319604"
/db_xref="SGD:S000000332"
/db_xref="GeneID:852425"
/translation="MHCPICHHRAHVVYCAHCINTSPSLLLKLKLDLILLKDENKELN
GKVEQILNEAMNYDQLDIKRMEKKKDPLMNSLMKLDVLRMKKNNNLIRHRIEQLNERI
YSKRNHISELKVEIDNYKCYKVGTGTDKLREQVEISDAKNKLAQVSKICESARDYKLN
LLNNWFVIQKLQDNFQIPFAIAFQPLISLKNFRILPLAITNDSINIMWKYISFFSDIL
MIKLPYTNKICEQPMFEFSDSIQTVVQRLIKLIINILQICRHLKLVPSTPMDIPWLLD
QYDVDGLFYNMVKRNKMKCRSVSLYWTFGMLYSMVLDNMNNPQRGHPARRTAPPPTVT
GPHDRWYVVG"
gene complement(494353..495339)
/gene="OPY1"
/locus_tag="YBR129C"
/db_xref="GeneID:852426"
mRNA complement(494353..495339)
/gene="OPY1"
/locus_tag="YBR129C"
/product="Opy1p"
/transcript_id="NM_001178477.1"
/db_xref="GI:296142794"
/db_xref="GeneID:852426"
CDS complement(494353..495339)
/gene="OPY1"
/locus_tag="YBR129C"
/note="hypothetical protein, overproduction blocks cell
cycle arrest in the presence of mating pheromone; the
authentic, non-tagged protein is detected in highly
purified mitochondria in high-throughput studies"
/codon_start=1
/product="Opy1p"
/protein_id="NP_009687.1"
/db_xref="GI:6319605"
/db_xref="SGD:S000000333"
/db_xref="GeneID:852426"
/translation="MIAGATAPSSQHEILIASNLIKKPSTSQNKTPTAQSSSGNNGAA
DGAPQGYHHHHHHHRHLWWPRTTDHQYWCVLRKNQFAYYKTRDEREAISVIPRFDILN
FKISELDGILTVYTPSKDLIFKFPRGQNEKVGMELMHNWKIALEKFLSSPSGNESVTT
GSDYDEEEDDDDLIVVDEKAGPSSSKHSCSLTMDEQLSREDKEFYRMFDPRNAEHQVC
SGILYTKVKKKKLFNRAKWQKFNVELTNTSFNLYSFKTGKLKKSIKLDKIIDCIELDN
NSKMKNDDTNFALITFDERLSFKAANDQDMVDWIINFKSGILIRKKLKAENI"
gene complement(495592..496869)
/gene="SHE3"
/locus_tag="YBR130C"
/db_xref="GeneID:852427"
mRNA complement(495592..496869)
/gene="SHE3"
/locus_tag="YBR130C"
/product="She3p"
/transcript_id="NM_001178478.3"
/db_xref="GI:398364974"
/db_xref="GeneID:852427"
CDS complement(495592..496869)
/gene="SHE3"
/locus_tag="YBR130C"
/note="Protein that acts as an adaptor between Myo4p and
the She2p-mRNA complex; part of the mRNA localization
machinery that restricts accumulation of certain proteins
to the bud; also required for cortical ER inheritance"
/codon_start=1
/product="She3p"
/protein_id="NP_009688.3"
/db_xref="GI:398364975"
/db_xref="SGD:S000000334"
/db_xref="GeneID:852427"
/translation="MSDQDNTQTSSSKLAPHHNIFMANLESSPTKDRNTSSQNASSSR
VIESLHDQIDMLTKTNLQLTTQSQNLLSKLELAQSKESKLLENLNLLKNENENLNSIF
ERKNKKLKELEKDYSELSNRYNEQKEKMDQLSKLAKNSSAIEQSCSEKLQNMEVNYNS
LLESQNLYRDHYSDEISKLNEKIGLLELELSNQNLNYGSDTSSNSDIELNLNKFNDSV
KDLKSLETEKDSKLSKIITHSLDELNLQSWLNLYQTNENLISTFAEKMDLKDVLKRND
EKISNKGAVVQTLKKNVQTQVESNNADALSSNNAQDMLPIKMVKLRKTPNTNDSSSNG
NSSNNKRRSFYTASPLLSSGSIPKSASPVLPGVKRTASVRKPSSSSSKTNVTHNNDPS
TSPTISVPPGVTRTVSSTHKKKGNSMVVHGAQS"
gene 497163..499277
/gene="CCZ1"
/locus_tag="YBR131W"
/gene_synonym="CVT16"
/db_xref="GeneID:852428"
mRNA 497163..499277
/gene="CCZ1"
/locus_tag="YBR131W"
/gene_synonym="CVT16"
/product="Ccz1p"
/transcript_id="NM_001178479.3"
/db_xref="GI:398364978"
/db_xref="GeneID:852428"
CDS 497163..499277
/gene="CCZ1"
/locus_tag="YBR131W"
/gene_synonym="CVT16"
/note="Protein involved in vacuolar assembly, essential
for autophagy and the cytoplasm-to-vacuole pathway"
/codon_start=1
/product="Ccz1p"
/protein_id="NP_009689.3"
/db_xref="GI:398364979"
/db_xref="SGD:S000000335"
/db_xref="GeneID:852428"
/translation="MRLHYITVFDPSRSTNENDTFKQLLLFHYFGTTDSIPSLNEKLS
IIGVIQGIWSLTSSCVNKDGEDLEKIIELNNDIIFCIKVESRFFISLAISNISDDQSA
IPLQYLSAYLWLSYRFFKLLNGSFSGFNKDFRKLTDLLNEFVIPFWNDIYLNLETVTN
RSFTVMWPGFYKRANFQHSSYNPGEKNNVEESWDAIILQNILLDKKSYLGLKDILVYH
LPKRTKAANRESMGTKTYGLVRNFTSDLNTLPDISNWLYHLHCTYGEISSHILTGNVH
FKEELQVEEEQERSRDTNGRDEEESQEQQRREHQETTQNNTSELSLSERVIHNVTLPI
SFAYDAIHEVSTTTGVSGSLSMIMDYVPKPHWPFISSSNKSADKNNYSNSNDNANSNA
PLMAQSEAVGGTIGNSRFGFLISPLNSDLLPSSYQALKLNLNFENSKDKEDFYNCLFW
YFDDFLIVIVCDPDFNKICERDYLKDLSFQLCQSMECLNNEILNSQNCDNVESFAYVI
RDNVTKEIDSSVPFGSPKFTSDESISTLQLAINGIDQFINDNSNSLSLANWNPITIMG
GSNAISKKNTTEGFGNGVNDKTQKFKRKYLNFLNLMSAEKLWDLQVDVLQFLTSLQNS
KRDPDYFQEERLLKLNNGVLCYIKENNSNLIIIIKNWFQNNGTSKAAKQRNRFSSDSS
KGSSLFQSLGRDVTDWWESREI"
gene complement(499652..501442)
/gene="AGP2"
/locus_tag="YBR132C"
/db_xref="GeneID:852429"
mRNA complement(499652..501442)
/gene="AGP2"
/locus_tag="YBR132C"
/product="Agp2p"
/transcript_id="NM_001178480.1"
/db_xref="GI:296142797"
/db_xref="GeneID:852429"
CDS complement(499652..501442)
/gene="AGP2"
/locus_tag="YBR132C"
/note="High affinity polyamine permease, preferentially
uses spermidine over putrescine; expression is
down-regulated by osmotic stress; plasma membrane
carnitine transporter, also functions as a low-affinity
amino acid permease"
/codon_start=1
/product="Agp2p"
/protein_id="NP_009690.1"
/db_xref="GI:6319608"
/db_xref="SGD:S000000336"
/db_xref="GeneID:852429"
/translation="MTKERMTIDYENDGDFEYDKNKYKTITTRIKSIEPSEGWLEPSG
SVGHINTIPEAGDVHVDEHEDRGSSIDDDSRTYLLYFTETRRKLENRHVQLIAISGVI
GTALFVAIGKALYRGGPASLLLAFALWCVPILCITVSTAEMVCFFPVSSPFLRLATKC
VDDSLAVMASWNFWFLECVQIPFEIVSVNTIIHYWRDDYSAGIPLAVQVVLYLLISIC
AVKYYGEMEFWLASFKIILALGLFTFTFITMLGGNPEHDRYGFRNYGESPFKKYFPDG
NDVGKSSGYFQGFLACLIQASFTIAGGEYISMLAGEVKRPRKVLPKAFKQVFVRLTFL
FLGSCLCVGIVCSPNDPDLTAAINEARPGAGSSPYVIAMNNLKIRILPDIVNIALITA
AFSAGNAYTYCSSRTFYGMALDGYAPKIFTRCNRHGVPIYSVAISLVWALVSLLQLNS
NSAVVLNWLINLITASQLINFVVLCIVYLFFRRAYHVQQDSLPKLPFRSWGQPYTAII
GLVSCSAMILIQGYTVFFPKLWNTQDFLFSYLMVFINIGIYVGYKFIWKRGKDHFKNP
HEIDFSKELTEIENHEIESSFEKFQYYSKA"
gene complement(501804..504287)
/gene="HSL7"
/locus_tag="YBR133C"
/db_xref="GeneID:852431"
mRNA complement(501804..504287)
/gene="HSL7"
/locus_tag="YBR133C"
/product="Hsl7p"
/transcript_id="NM_001178481.1"
/db_xref="GI:296142798"
/db_xref="GeneID:852431"
CDS complement(501804..504287)
/gene="HSL7"
/locus_tag="YBR133C"
/EC_number="2.1.1.125"
/note="Protein arginine N-methyltransferase; exhibits
septin and Hsl1p-dependent bud neck localization and
periodic Hsl1p-dependent phosphorylation; required along
with Hsl1p for bud neck recruitment, phosphorylation, and
degradation of Swe1p; relocalizes away from bud neck upon
DNA replication stress"
/codon_start=1
/product="Hsl7p"
/protein_id="NP_009691.1"
/db_xref="GI:6319610"
/db_xref="SGD:S000000337"
/db_xref="GeneID:852431"
/translation="MHSNVFVGVKPGFNHKQHSKKSRFLENVSSHSPELPSNYDYVLL
PITTPRYKEIVGQVFKDFQRQSIQNWKPLQIPEPQLQDICIPPFNVKKLDNDDTPSYI
GLLSSWLELESRDPNVRDLGLKVLLNECKYARFVGINKLILAPPRDLSNLQLYGQMIY
RLLQNRIVFAAPALTISISLPLYEDSDPLATWELWNTVRKQCEYHPSLTISLALPRTR
TPSYVLNRWLAEPVSCLLVSSSIFASNQYDYPVLHKFNQNLILKFQKVNGDSQILGNE
LCVILHGMEKYANNVKGGESAYLEYINYLLKKGDKVLNSNSNHQFLLQEDSRIMPPLK
PHSDNLLNSTYLTFEKDLVKYDLYESAILEALQDLAPRASAKRPLVILVAGAGRGPLV
DRTFKIISMLFMDSKVSIIAIEKNPQAYLYLQKRNFDCWDNRVKLIKEDMTKWQINEP
SEKRIQIDLCISELLGSFGCNELSPECLWSIEKYHSHNDTIFIPRSYSSYIAPISSPL
FYQKLSQTNRSLEAPWIVHRVPYCILSSRVNEVWRFEHPMAQKDTVQDEDDFTVEFSQ
SSLNEFKIKHRGEIHGFIGFFSANLYNNIFLSTLPNDSTVRLKFSEETLMNTRREENL
IKKCDHTPNMTSWSPIIFPLKQPISFIDDSELSVLMSRIHSDTEQKVWYEWSLESFIY
LMLSNYTSAVTAASMTIPRSIVTDDTKTLAHNRHYSATTNQKLDNQIDLDQDIENEEE
QGFLSNLETGWQSVQDIHGLSETAKPDHLDSINKPMFDLKSTKALEPSNELPRHEDLE
EDVPEVHVRVKTSVSTLHNVCGRAFSLPL"
gene 504854..505306
/gene="CKS1"
/locus_tag="YBR135W"
/db_xref="GeneID:852432"
mRNA 504854..505306
/gene="CKS1"
/locus_tag="YBR135W"
/product="Cks1p"
/transcript_id="NM_001178483.3"
/db_xref="GI:398364998"
/db_xref="GeneID:852432"
CDS 504854..505306
/gene="CKS1"
/locus_tag="YBR135W"
/note="Cyclin-dependent protein kinase regulatory subunit
and adaptor; modulates proteolysis of M-phase targets
through interactions with the proteasome; role in
transcriptional regulation, recruiting proteasomal
subunits to target gene promoters"
/codon_start=1
/product="Cks1p"
/protein_id="NP_009693.3"
/db_xref="GI:398364999"
/db_xref="SGD:S000000339"
/db_xref="GeneID:852432"
/translation="MYHHYHAFQGRKLTDQERARVLEFQDSIHYSPRYSDDNYEYRHV
MLPKAMLKVIPSDYFNSEVGTLRILTEDEWRGLGITQSLGWEHYECHAPEPHILLFKR
PLNYEAELRAATAAAQQQQQQQQQQQQQQQQHQTQSISNDMQVPPQIS"
gene 505668..512774
/gene="MEC1"
/locus_tag="YBR136W"
/gene_synonym="ESR1; RAD31; SAD3"
/db_xref="GeneID:852433"
mRNA 505668..512774
/gene="MEC1"
/locus_tag="YBR136W"
/gene_synonym="ESR1; RAD31; SAD3"
/product="Mec1p"
/transcript_id="NM_001178484.3"
/db_xref="GI:398365008"
/db_xref="GeneID:852433"
CDS 505668..512774
/gene="MEC1"
/locus_tag="YBR136W"
/gene_synonym="ESR1; RAD31; SAD3"
/EC_number="2.7.11.1"
/note="Genome integrity checkpoint protein and PI kinase
superfamily member; signal transducer required for cell
cycle arrest and transcriptional responses prompted by
damaged or unreplicated DNA; regulates P-body formation
induced by replication stress; monitors and participates
in meiotic recombination; associates with shortened,
dysfunctional telomeres"
/codon_start=1
/product="Mec1p"
/protein_id="NP_009694.3"
/db_xref="GI:398365009"
/db_xref="SGD:S000000340"
/db_xref="GeneID:852433"
/translation="MESHVKYLDELILAIKDLNSGVDSKVQIKKVPTDPSSSQEYAKS
LKILNTLIRNLKDQRRNNIMKNDTIFSKTVSALALLLEYNPFLLVMKDSNGNFEIQRL
IDDFLNISVLNYDNYHRIWFMRRKLGSWCKACVEFYGKPAKFQLTAHFENTMNLYEQA
LTEVLLGKTELLKFYDTLKGLYILLYWFTSEYSTFGNSIAFLDSSLGFTKFDFNFQRL
IRIVLYVFDSCELAALEYAEIQLKYISLVVDYVCNRTISTALDAPALVCCEQLKFVLT
TMHHFLDNKYGLLDNDPTMAKGILRLYSLCISNDFSKCFVDHFPIDQWADFSQSEHFP
FTQLTNKALSIVYFDLKRRSLPVEALKYDNKFNIWVYQSEPDSSLKNVTSPFDDRYKQ
LEKLRLLVLKKFNKTERGTLLKYRVNQLSPGFFQRAGNDFKLILNEASVSIQTCFKTN
NITRLTSWTVILGRLACLESEKFSGTLPNSTKDMDNWYVCHLCDIEKTGNPFVRINPN
RPEAAGKSEIFRILHSNFLSHPNIDEFSESLLSGILFSLHRIFSHFQPPKLTDGNGQI
NKSFKLVQKCFMNSNRYLRLLSTRIIPLFNISDSHNSEDEHTATLIKFLQSQKLPVVK
ENLVIAWTQLTLTTSNDVFDTLLLKLIDIFNSDDYSLRIMMTLQIKNMAKILKKTPYQ
LLSPILPVLLRQLGKNLVERKVGFQNLIELLGYSSKTILDIFQRYIIPYAIIQYKSDV
LSEIAKIMCDGDTSLINQMKVNLLKKNSRQIFAVALVKHGLFSLDILETLFLNRAPTF
DKGYITAYLPDYKTLAEITKLYKNSVTKDASDSENANMILCSLRFLITNFEKDKRHGS
KYKNINNWTDDQEQAFQKKLQDNILGIFQVFSSDIHDVEGRTTYYEKLRVINGISFLI
IYAPKKSIISALAQISICLQTGLGLKEVRYEAFRCWHLLVRHLNDEELSTVIDSLIAF
ILQKWSEFNGKLRNIVYSILDTLIKEKSDLILKLKPYTTLALVGKPELGILARDGQFA
RMVNKIRSTTDLIPIFANNLKSSNKYVINQNLDDIEVYLRRKQTERSIDFTPKKVGQT
SDITLVLGALLDTSHKFRNLDKDLCEKCAKCISMIGVLDVTKHEFKRTTYSENEVYDL
NDSVQTIKFLIWVINDILVPAFWQSENPSKQLFVALVIQESLKYCGLSSESWDMNHKE
LYPNEAKLWEKFNSVSKTTIYPLLSSLYLAQSWKEYVPLKYPSNNFKEGYKIWVKRFT
LDLLKTGTTENHPLHVFSSLIREDDGSLSNFLLPYISLDIIIKAEKGTPYADILNGII
IEFDSIFTCNLEGMNNLQVDSLRMCYESIFRVFEYCKKWATEFKQNYSKLHGTFIIKD
TKTTNMLLRIDEFLRTTPSDLLAQRSLETDSFERSALYLEQCYRQNPHDKNQNGQLLK
NLQITYEEIGDIDSLDGVLRTFATGNLVSKIEELQYSENWKLAQDCFNVLGKFSDDPK
TTTRMLKSMYDHQLYSQIISNSSFHSSDGKISLSPDVKEWYSIGLEAANLEGNVQTLK
NWVEQIESLRNIDDREVLLQYNIAKALIAISNEDPLRTQKYIHNSFRLIGTNFITSSK
ETTLLKKQNLLMKLHSLYDLSFLSSAKDKFEYKSNTTILDYRMERIGADFVPNHYILS
MRKSFDQLKMNEQADADLGKTFFTLAQLARNNARLDIASESLMHCLERRLPQAELEFA
EILWKQGENDRALKIVQEIHEKYQENSSVNARDRAAVLLKFTEWLDLSNNSASEQIIK
QYQDIFQIDSKWDKPYYSIGLYYSRLLERKKAEGYITNGRFEYRAISYFLLAFEKNTA
KVRENLPKVITFWLDIAAASISEAPGNRKEMLSKATEDICSHVEEALQHCPTYIWYFV
LTQLLSRLLHSHQSSAQIIMHILLSLAVEYPSHILWYITALVNSNSSKRVLRGKHILE
KYRQHSQNPHDLVSSALDLTKALTRVCLQDVKSITSRSGKSLEKDFKFDMNVAPSAMV
VPVRKNLDIISPLESNSMRGYQPFRPVVSIIRFGSSYKVFSSLKKPKQLNIIGSDGNI
YGIMCKKEDVRQDNQYMQFATTMDFLLSKDIASRKRSLGINIYSVLSLREDCGILEMV
PNVVTLRSILSTKYESLKIKYSLKSLHDRWQHTAVDGKLEFYMEQVDKFPPILYQWFL
ENFPDPINWFNARNTYARSYAVMAMVGHILGLGDRHCENILLDIQTGKVLHVDFDCLF
EKGKRLPVPEIVPFRLTPNLLDALGIIGTEGTFKKSSEVTLALMRKNEVALMNVIETI
MYDRNMDHSIQKALKVLRNKIRGIDPQDGLVLSVAGQTETLIQEATSEDNLSKMYIGW
LPFW"
gene 513044..513583
/locus_tag="YBR137W"
/db_xref="GeneID:852434"
mRNA 513044..513583
/locus_tag="YBR137W"
/product="hypothetical protein"
/transcript_id="NM_001178485.2"
/db_xref="GI:330443452"
/db_xref="GeneID:852434"
CDS 513044..513583
/locus_tag="YBR137W"
/note="hypothetical protein; localized to the cytoplasm;
binds to Replication Protein A (RPA); also interacts with
Sgt2p; YBR137W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009695.2"
/db_xref="GI:330443453"
/db_xref="SGD:S000000341"
/db_xref="GeneID:852434"
/translation="MVVLDKKLLERLTSRKVPLEELEDMEKRCFLSTFTYQDAFDLGT
YIRNAVKENFPEKPVAIDISLPNGHCLFRTVTYGGSALDNDFWIQRKKKTALRFGHSS
FYMGCKKGDKTPEEKFFVDSKEYAFHGGAVLIQSERSDYPYACLTISGLKQEEDHLMA
VSSLIAFANESLEEDLNLD"
gene complement(513762..515336)
/locus_tag="YBR138C"
/db_xref="GeneID:852435"
mRNA complement(513762..515336)
/locus_tag="YBR138C"
/product="hypothetical protein"
/transcript_id="NM_001178486.2"
/db_xref="GI:330443454"
/db_xref="GeneID:852435"
CDS complement(513762..515336)
/locus_tag="YBR138C"
/note="Cytoplasmic hypothetical protein, potentially
phosphorylated by Cdc28p; YBR138C is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009696.2"
/db_xref="GI:330443455"
/db_xref="SGD:S000000342"
/db_xref="GeneID:852435"
/translation="MEKDQIQPRVLESVDTNSLSLLSSNTSSNMNSNTNNKLSIIASD
ISTGSVLSRPLTPPVVQDIENNSMLQWQFEKKEFIFDSNSTPSKQAKPLQRNSPYQGN
SQSENQNQQLLNVRKRRSQLIGAKPKIPSKLYQSVSKLDLIDDKSFTSLPIAPPCNIE
TNEDDSGNNEYNNNKKRPRLNPVNELRVHNNKRNRYVSYGPSLDTKNYELTENTSQDI
PPLVLVEDYIPYTQSKSTKKMVSISDLKSKLSKRRDNHIPLRVKNSYSEINKETNRNS
FEPNSLTLIPHILRNTEENRDESNNPLDFIKEEIEISDISIPNSIENMVVNLVNIPSS
NKSYDDLYLSELNVHSQLRKCVICEKALYEISSRLLNSGYYKEIVCEQCTVRYEEAAK
IFENCEFESSMDESNLSSGTFSDLENSAEPFHLSTDVPKKINRHIEDNKIDLKKEISK
KKDSFSKELIERLQLQLLENDKSIKHHFNKDAMGSKSMNWFLEARRKLKWKWRINGLL
PHFLRNQNSDRLNFQP"
gene 515664..517190
/locus_tag="YBR139W"
/db_xref="GeneID:852436"
mRNA 515664..517190
/locus_tag="YBR139W"
/product="carboxypeptidase C"
/transcript_id="NM_001178487.3"
/db_xref="GI:398365030"
/db_xref="GeneID:852436"
CDS 515664..517190
/locus_tag="YBR139W"
/EC_number="3.4.16.-"
/note="Putative serine type carboxypeptidase with a role
in phytochelatin synthesis; green fluorescent protein
(GFP)-fusion protein localizes to the vacuole; expression
induced by nitrogen limitation in a GLN3, GAT1-independent
manner"
/codon_start=1
/product="carboxypeptidase C"
/protein_id="NP_009697.3"
/db_xref="GI:398365031"
/db_xref="SGD:S000000343"
/db_xref="GeneID:852436"
/translation="MKYLNLVFVLQLLISIKYASFGRAFSLFEDDTTFANLDKQLKLP
QNTQQTLKLDRLNHDDPLFTTFISSVDTDYSLRLRTVDPSKLGIDTVKQWSGYMDYKD
SKHFFYWFFESRNDPANDPIILWLNGGPGCSSFTGLLFELGPSSIGADMKPIHNPYSW
NNNASMIFLEQPLGVGFSYGDEKVSSTKLAGKDAYIFLELFFEAFPHLRSNDFHIAGE
SYAGHYIPQIAHEIVVKNPERTFNLTSVMIGNGITDPLIQADYYEPMACGKGGYHPVL
SSEECEKMSKAAGRCRRLNKLCYASKSSLPCIVATAYCDSALLEPYINTGLNVYDIRG
PCEDNSTDGMCYTGLRYVDQYMNFPEVQETLGSDVHNYSGCDNDVFTGFLFTGDGSKP
FQQYIAELLNHNIPVLIYAGDKDYICNWLGNHAWSNELEWINKRRYQRRMLRPWVSKE
TGEELGQVKNYGPFTFLRIYDAGHMVPYDQPEASLEMVNSWISGNRAFSDLSTLENAS
"
gene complement(517350..526628)
/gene="IRA1"
/locus_tag="YBR140C"
/gene_synonym="GLC1; PPD1"
/db_xref="GeneID:852437"
mRNA complement(517350..526628)
/gene="IRA1"
/locus_tag="YBR140C"
/gene_synonym="GLC1; PPD1"
/product="Ira1p"
/transcript_id="NM_001178488.3"
/db_xref="GI:398365032"
/db_xref="GeneID:852437"
CDS complement(517350..526628)
/gene="IRA1"
/locus_tag="YBR140C"
/gene_synonym="GLC1; PPD1"
/note="GTPase-activating protein that negatively regulates
RAS by converting it from the GTP- to the GDP-bound
inactive form, required for reducing cAMP levels under
nutrient limiting conditions, mediates membrane
association of adenylate cyclase"
/codon_start=1
/product="Ira1p"
/protein_id="NP_009698.3"
/db_xref="GI:398365033"
/db_xref="SGD:S000000344"
/db_xref="GeneID:852437"
/translation="MNQSDPQDKKNFPMEYSLTKHLFFDRLLLVLPIESNLKTYADVE
ADSVFNSCRSIILNIAITKDLNPIIENTLGLIDLIVQDEEITSDNITDDIAHSILVLL
RLLSDVFEYYWDQNNDFKKIRNDNYKPGFSSHRPNFHTSRPKHTRINPALATMLLCKI
SKLKFNTRTLKVLQNMSHHLSGSATISKSSILPDSQEFLQKRNYPAYTEKIDLTIDYI
QRFISASNHVEFTKCVKTKVVAPLLISHTSTELGVVNHLDLFGCEYLTDKNLLAYLDI
LQHLSSYMKRTIFHSLLLYYASKAFLFWIMARPKEYVKIYNNLISSDYNSPSSSSDNG
GSNNSDKTSISQLVSLLFDDVYSTFSVSSLLTNVNNDHHYHLHHSSSSSKTTNTNSPN
SISKTSIKQSSVNASGNVSPSQFSTGNDASPTSPMASLSSPLNTNILGYPLSPITSTL
GQANTSTSTTAATTKTDADTPSTMNTNNNNNNNNSANLNNIPQRIFSLDDISSFNSSR
KSLNLDDSNSLFLWDTSQHSNASMTNTNMHAGVNNSQSQNDQSSLNYMENIMELYSNY
TGSELSSHTAILRFLVVLTLLDSEVYDEMNSNSYRKISEPIMNINPKDSNTSSWGSAS
KNPSIRHLTHGLKKLTLQQGRKRNVKFLTYLIRNLNGGQFVSDVSLIDSIRSILFLMT
MTSSISQIDSNIASVIFSKRFYNLLGQNLEVGTNWNSATANTFISHCVERNPLTHRRL
QLEFFASGLQLDSDLFLRHLQLEKELNHIDLPKISLYTEGFRVFFHLVSTKKLHEDIA
EKTSSVLKRLFCIIADILLKATPYFDDNVTKIIASILDGHILDQFDAARTLSNDDHVS
FDAATSVYTEPTEIIHNSSDASLVSSLSQSPLSINSGSNITNTRTWDIQSILPTLSNR
SSASDLSLSNILTNPLEAQQNNNANLLAHRLSGVPTTKRYASPNDSERSRQSPYSSPP
QLQQSDLPSPLSVLSSSAGFSSNHSITATPTILKNIKSPKPNKTKKIADDKQLKQPSY
SRVILSDNDEARKIMMNIFSIFKRMTNWFIRPDANTEFPKTFTDIIKPLFVSILDSNQ
RLQVTARAFIEIPLSYIATFEDIDNDLDPRVLNDHYLLCTYAVTLFASSLFDLKLENA
KREMLLDIIVKFQRVRSYLSNLAEKHNLVQAIITTERLTLPLLVGAVGSGIFISLYCS
RGNTPRLIKISCCEFLRSLRFYQKYVGALDQYSIYNIDFIDAMAQDNFTASGSVALQR
RLRNNILTYIKGSDSILLDSMDVIYKKWFYFSCSKSVTQEELVDFRSLAGILASMSGI
LSDMQELEKSKSAPDNEGDSLSFESRNPAYEVHKSLKLELTKKMNFFISKQCQWLNNP
NLLTRENSRDILSIELHPLSFNLLFNNLGLKIDELMSIDLSKSHEDSSFVLLEQIIII
IRTILKRDDDEKIMLLFSTDLLDAVDKLIEIVEKISIKSSKYYKGIIQMSKMFRAFEH
SEKNLGISNHFHLKNKWLKLVIGWFKLSINKDYDFENLSRPLREMDLQKRDEDFLYID
TSIESAKALAYLTHNVPLEIPPSSSKEDWNRSSTVSFGNHFTILLKGLEKSADLNQFP
VSLRHKISILNENVIIALTNLSNANVNVSLKFTLPMGYSPNKDIRIAFLRVFIDIVTN
YPVNPEKHEMDKMLAIDDFLKYIIKNPILAFFGSLACSPADVDLYAGGFLNAFDTRNA
SHILVTELLKQEIKRAARSDDILRRNSCATRALSLYTRSRGNKYLIKTLRPVLQGIVD
NKESFEIDKMKPGSENSEKMLDLFEKYMTRLIDAITSSIDDFPIELVDICKTIYNAAS
VNFPEYAYIAVGSFVFLRFIGPALVSPDSENIIIVTHAHDRKPFITLAKVIQSLANGR
ENIFKKDILVSKEEFLKTCSDKIFNFLSELCKIPTNNFTVNVREDPTPISFDYSFLHK
FFYLNEFTIRKEIINESKLPGEFSFLKNTVMLNDKILGVLGQPSMEIKNEIPPFVVEN
REKYPSLYEFMSRYAFKKVDMKEEEEDNAPFVHEAMTLDGIQIIVVTFTNCEYNNFVM
DSLVYKVLQIYARMWCSKHYVVIDCTTFYGGKANFQKLTTLFFSLIPEQASSNCMGCY
YFNVNKSFMDQWASSYTVENPYLVTTIPRCFINSNTDQSLIKSLGLSGRSLEVLKDVR
VTLHDITLYDKEKKKFCPVSLKIGNKYFQVLHEIPQLYKVTVSNRTFSIKFNNVYKIS
NLISVDVSNTTGVSSEFTLSLDNEEKLVFCSPKYLEIVKMFYYAQLKMEEDFGTDFSN
DISFSTSSSAVNASYCNVKEVGEIISHLSLVILVGLFNEDDLVKNISYNLLVATQEAF
NLDFGTRLHKSPETYVPDDTTTFLALIFKAFSESSTELTPYIWKYMLDGLENDVIPQE
HIPTVVCSLSYWVPNLYEHVYLANDEEGPEAISRIIYSLIRLTVKEPNFTTAYLQQIW
FLLALDGRLTNVIVEEIVSHALDRDSENRDWMKAVSILTSFPTTEIACQVIEKLINMI
KSFLPSLAVEASAHSWSELTILSKISVSIFFESPLLSQMYLPEILFAVSLLIDVGPSE
IRVSLYELLMNVCHSLTNNESLPERNRKNLDIVCATFARQKLNFISGFSQEKGRVLPN
FAASSFSSKFGTLDLFTKNIMLLMEYGSISEGAQWEAKYKKYLMDAIFGHRSFFSARA
MMILGIMSKSHTSLFLCKELLVETMKVFAEPVVDDEQMFIIIAHVFTYSKIVEGLDPS
SELMKELFWLATICVESPHPLLFEGGLLFMVNCLKRLYTVHLQLGFDGKSLAKKLMES
RNFAATLLAKLESYNGCIWNEDNFPHIILGFIANGLSIPVVKGAALDCLQALFKNTYY
ERKSNPKSSDYLCYLFLLHLVLSPEQLSTLLLEVGFEDELVPLNNTLKVPLTLINWLS
SDSDKSNIVLYQGALLFSCVMSDEPCKFRFALLMRYLLKVNPICVFRFYTLTRKEFRR
LSTLEQSSEAVAVSFELIGMLVTHSEFNYLEEFNDEMVELLKKRGLSVVKPLDIFDQE
HIEKLKGEGEHQVAIYERKRLATMILARMSCS"
gene complement(527025..528038)
/locus_tag="YBR141C"
/db_xref="GeneID:852438"
mRNA complement(527025..528038)
/locus_tag="YBR141C"
/product="hypothetical protein"
/transcript_id="NM_001178489.2"
/db_xref="GI:330443456"
/db_xref="GeneID:852438"
CDS complement(527025..528038)
/locus_tag="YBR141C"
/note="Putative S-adenosylmethionine-dependent
methyltransferase; green fluorescent protein (GFP)-fusion
protein localizes to the nucleolus; YBR141C is not an
essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009699.2"
/db_xref="GI:330443457"
/db_xref="SGD:S000000345"
/db_xref="GeneID:852438"
/translation="MHSRKSKSITGKRKQVGSNVTRVIKPQKTRRIIRRFHHLINKRQ
SICKFLCLKENLDDSNEEKNDKIIRLSIKGNVRLGKYYEDGKSQSFNDAMESQLLRLH
SLIKNESKSKDTSDLAVMYTLLGYIMNQINKLGGLETYQIASQNGQLKERGGDTSKLL
EKWIRSSFENCPGAVALEIGSLSSGNRISRCALFRNVVRIDLEEHEGVIKQDFMERPL
PRNENDKFDLISCSLVLNFVKNHRDRGAMCHRMVKFLKPQGYIFIVLPQACVTHSRYC
DKTLLQNLLGSIGLIMLNSHQSNKLYYCLYQLQVVPPQPSSFSKRIKVNDGPGLNNFG
ITL"
gene 528317..530638
/gene="MAK5"
/locus_tag="YBR142W"
/db_xref="GeneID:852439"
mRNA 528317..530638
/gene="MAK5"
/locus_tag="YBR142W"
/product="Mak5p"
/transcript_id="NM_001178490.1"
/db_xref="GI:296142806"
/db_xref="GeneID:852439"
CDS 528317..530638
/gene="MAK5"
/locus_tag="YBR142W"
/EC_number="3.6.1.-"
/note="Essential nucleolar protein, putative DEAD-box RNA
helicase required for maintenance of M1 dsRNA virus;
involved in biogenesis of large (60S) ribosomal subunits"
/codon_start=1
/product="Mak5p"
/protein_id="NP_009700.1"
/db_xref="GI:6319618"
/db_xref="SGD:S000000346"
/db_xref="GeneID:852439"
/translation="MGKKRAPQKGKTVTKPQEIIVDESKLNWKPVDIPDTLDDFGGFY
GLEEIDGVDVKVVDGKVTFVTKKDSKVLKDSNKEKVGDDQESVENESGSDSESELLEF
KNLDDIKEGELSAASYSSSDEDEQGNIESSKLTDPSEDVDEDVDEDVLKENVFNKDIN
IDDISPVNLPEWTNLAPLSMTILQSLQNLNFLRPTEIQKKSIPVIMQGVDVMGKASTG
SGKTLAYGIPIVEKLISNFSQKNKKPISLIFTPTRELAHQVTDHLKKICEPVLAKSQY
SILSLTGGLSIQKQQRLLKYDNSGQIVIATPGRFLELLEKDNTLIKRFSKVNTLILDE
ADRLLQDGHFDEFEKIIKHLLVERRKNRENSEGSSKIWQTLIFSATFSIDLFDKLSSS
RQVKDRRFKNNEDELNAVIQHLMSKIHFNSKPVIIDTNPESKVSSQIKESLIECPPLE
RDLYCYYFLTMFPGTTLIFCNAIDSVKKLTVYLNNLGIPAFQIHSSMTQKNRLKSLER
FKQQSAKQKTINHSNPDSVQLSTVLIASDVAARGLDIPGVQHVIHYHLPRSTDIYIHR
SGRTARAGSEGVSAMICSPQESMGPLRKLRKTLATKNSVSTDLNSRSTNRKPIKWQNT
VPLLPIETDILSQLRERSRLAGELADHEIASNSLRKDDNWLKKAADELGIDVDSDEDD
ISKSNSDTFLLKNKNKKMQKTINKDKVKAMRATLNELLSVPIRKDRRQKYLTGGLVNL
ADNLVKKRGHNSIIGHEKTNALETLKKKKKRNN"
gene complement(530869..532182)
/gene="SUP45"
/locus_tag="YBR143C"
/gene_synonym="SAL4; SUP1; SUP47"
/db_xref="GeneID:852440"
mRNA complement(530869..532182)
/gene="SUP45"
/locus_tag="YBR143C"
/gene_synonym="SAL4; SUP1; SUP47"
/product="Sup45p"
/transcript_id="NM_001178491.3"
/db_xref="GI:398365060"
/db_xref="GeneID:852440"
CDS complement(530869..532182)
/gene="SUP45"
/locus_tag="YBR143C"
/gene_synonym="SAL4; SUP1; SUP47"
/note="Polypeptide release factor (eRF1) in translation
termination; mutant form acts as a recessive omnipotent
suppressor; methylated by Mtq2p-Trm112p in ternary complex
eRF1-eRF3-GTP; mutation of methylation site confers
resistance to zymocin; has a role in cytokinesis through
interaction with Mlc1p"
/codon_start=1
/product="Sup45p"
/protein_id="NP_009701.3"
/db_xref="GI:398365061"
/db_xref="SGD:S000000347"
/db_xref="GeneID:852440"
/translation="MDNEVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPL
YQKMLTDEYGTASNIKSRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDG
KEKKVTFDIEPYKPINTSLYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSG
NTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNV
KGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGENGFNQAIELSAEALANVK
YVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENLETIRYTFKDAE
DNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKNFGATLEFITDKSS
EGAQFVTGFGGIGAMLRYKVNFEQLVDESEDEYYDEDEGSDYDFI"
gene 533762..534817
/gene="ADH5"
/locus_tag="YBR145W"
/db_xref="GeneID:852442"
mRNA 533762..534817
/gene="ADH5"
/locus_tag="YBR145W"
/product="alcohol dehydrogenase ADH5"
/transcript_id="NM_001178493.3"
/db_xref="GI:398365068"
/db_xref="GeneID:852442"
CDS 533762..534817
/gene="ADH5"
/locus_tag="YBR145W"
/EC_number="1.1.1.190"
/EC_number="1.1.1.1"
/note="Alcohol dehydrogenase isoenzyme V; involved in
ethanol production; ADH5 has a paralog, ADH1, that arose
from the whole genome duplication"
/codon_start=1
/product="alcohol dehydrogenase ADH5"
/protein_id="NP_009703.3"
/db_xref="GI:398365069"
/db_xref="SGD:S000000349"
/db_xref="GeneID:852442"
/translation="MPSQVIPEKQKAIVFYETDGKLEYKDVTVPEPKPNEILVHVKYS
GVCHSDLHAWHGDWPFQLKFPLIGGHEGAGVVVKLGSNVKGWKVGDFAGIKWLNGTCM
SCEYCEVGNESQCPYLDGTGFTHDGTFQEYATADAVQAAHIPPNVNLAEVAPILCAGI
TVYKALKRANVIPGQWVTISGACGGLGSLAIQYALAMGYRVIGIDGGNAKRKLFEQLG
GEIFIDFTEEKDIVGAIIKATNGGSHGVINVSVSEAAIEASTRYCRPNGTVVLVGMPA
HAYCNSDVFNQVVKSISIVGSCVGNRADTREALDFFARGLIKSPIHLAGLSDVPEIFA
KMEKGEIVGRYVVETSK"
gene 535260..536096
/gene="MRPS9"
/locus_tag="YBR146W"
/db_xref="GeneID:852443"
mRNA 535260..536096
/gene="MRPS9"
/locus_tag="YBR146W"
/product="mitochondrial 37S ribosomal protein MRPS9"
/transcript_id="NM_001178494.1"
/db_xref="GI:296142809"
/db_xref="GeneID:852443"
CDS 535260..536096
/gene="MRPS9"
/locus_tag="YBR146W"
/note="Mitochondrial ribosomal protein of the small
subunit"
/codon_start=1
/product="mitochondrial 37S ribosomal protein MRPS9"
/protein_id="NP_009704.1"
/db_xref="GI:6319622"
/db_xref="SGD:S000000350"
/db_xref="GeneID:852443"
/translation="MFSRLSLFRRAALAPAPMRMSFRTIYQKTEDELPRRIVPKLATF
YSANPNHEDRINRLERLLRKYIKLPSQNNNEAQQTKAPWISFDEYALIGGGTKLKPTQ
YTQLLYMLNKLHNIDPQLTNDEITSELSQYYKKSSMLSNNIKIKTLDEFGRSIAVGKR
KSSTAKVFVVRGTGEILVNGRQLNDYFLKMKDRESIMYPLQVIESVGKYNIFATTSGG
GPTGQAESIMHAIAKALVVFNPLLKSRLHKAGVLTRDYRHVERKKPGKKKARKMPTWV
KR"
gene 536575..537465
/gene="RTC2"
/locus_tag="YBR147W"
/gene_synonym="RRT11; YPQ3"
/db_xref="GeneID:852444"
mRNA 536575..537465
/gene="RTC2"
/locus_tag="YBR147W"
/gene_synonym="RRT11; YPQ3"
/product="Rtc2p"
/transcript_id="NM_001178495.1"
/db_xref="GI:296142810"
/db_xref="GeneID:852444"
CDS 536575..537465
/gene="RTC2"
/locus_tag="YBR147W"
/gene_synonym="RRT11; YPQ3"
/note="Putative vacuolar membrane transporter for cationic
amino acids; likely contributes to amino acid homeostasis
by exporting cationic amino acids from the vacuole;
positive regulation by Lys14p suggests that lysine may be
the primary substrate; member of the PQ-loop family, with
seven transmembrane domains; similar to mammalian PQLC2
vacuolar transporter"
/codon_start=1
/product="Rtc2p"
/protein_id="NP_009705.1"
/db_xref="GI:6319623"
/db_xref="SGD:S000000351"
/db_xref="GeneID:852444"
/translation="MKLIPIILNAKNLSGMAGSISICCWIVVFVPQIYENFRRQSAEG
LSLLFIVLWLLGDIFNVMGAMMQNLLPTMIILAAYYTLADLILLIQCMWYDKEKKSIL
QEVKKNVDPVHLPPANPINETVLQDVFNEYEPLLPRIEEEDSQSYSSLELGRTIVVKE
RENFFNDFLIVSGVLIAGILSWYISYCSGLDNGIPKKKPAFEQINLPAQILGYLSAIL
YLGSRIPQIVLNFKRKSCEGVSFLFFLFACLGNTSFIISVLSASWLIGSAGTLLMDFT
VFIQFFLYAKPKYEKILIDN"
gene 537876..539705
/gene="YSW1"
/locus_tag="YBR148W"
/db_xref="GeneID:852445"
mRNA 537876..539705
/gene="YSW1"
/locus_tag="YBR148W"
/product="Ysw1p"
/transcript_id="NM_001178496.3"
/db_xref="GI:398365084"
/db_xref="GeneID:852445"
CDS 537876..539705
/gene="YSW1"
/locus_tag="YBR148W"
/note="Protein required for normal prospore membrane
formation; interacts with Gip1p, which is the
meiosis-specific regulatory subunit of the Glc7p protein
phosphatase; expressed specifically in spores and
localizes to the prospore membrane"
/codon_start=1
/product="Ysw1p"
/protein_id="NP_009706.3"
/db_xref="GI:398365085"
/db_xref="SGD:S000000352"
/db_xref="GeneID:852445"
/translation="MSSLADTVEGSEAKRGRFSNNALTSDTGILQKNSTLRNWFLKPT
ADLKNSCEDRVEDDVNDVYLNDKNSQKSVEERKLGRKVRSFFKQTNSNKDESVLEDED
DALVWKKTSNKCAKKENSHDIQKGSFTKKIRNSIFKSANDVKEFRNENNLLLPVELSS
DDENESHFTDANSHVMQSKSPEKIPSKDQCLTKGAKNKGLKKEYEKSFEEYSDDSDDE
FSPATPPENVLEGPYKFVFQTPNTFTSQPNITVENDFHKGGRHVIDYLNKKLATMNID
IDLTSGGKQNVSWEEELDQLSDHVIESITNHISKGRMHAQEKQDELEKLKLENLNLST
LKQENLQHKQEINSLKDNLESISKKNNDLILEMNKLKKKSTNNKTNEYISTDENENEE
ITKSNMGPGILELNVNETSKKLQQSTFKPSKYLPRETRNNENRLKHLEKRIFGLEKSL
EKKKKQVRADSVRLDLNRYTIDQFLTLLKSLSEVLQFHNVYGNDLKENDDNIIKIETC
CSALNMKNCFEDSSFRLQENSFKRQLGPLFANINFSLIDQLTMNFRFYERSANFQKET
IGGLRMMLQDKDNYIKTLMQHLKKKESTKLIKDSKNGASTLTS"
gene 539987..541021
/gene="ARA1"
/locus_tag="YBR149W"
/db_xref="GeneID:852446"
mRNA 539987..541021
/gene="ARA1"
/locus_tag="YBR149W"
/product="D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA1"
/transcript_id="NM_001178497.3"
/db_xref="GI:398365090"
/db_xref="GeneID:852446"
CDS 539987..541021
/gene="ARA1"
/locus_tag="YBR149W"
/EC_number="1.1.1.117"
/note="NADP+ dependent arabinose dehydrogenase, involved
in carbohydrate metabolism; purified as homodimer;
naturally occurs with a N-terminus degradation product"
/codon_start=1
/product="D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA1"
/protein_id="NP_009707.3"
/db_xref="GI:398365091"
/db_xref="SGD:S000000353"
/db_xref="GeneID:852446"
/translation="MSSSVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPH
EKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVW
PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTM
YAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETH
PHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAEKYNVTGNDLLISYHI
RQGTIVIPRSLNPVRISSSIEFASLTKDELQELNDFGEKYPVRFIDEPFAAILPEFTG
NGPNLDNLKY"
gene complement(541209..544493)
/gene="TBS1"
/locus_tag="YBR150C"
/db_xref="GeneID:852447"
mRNA complement(541209..544493)
/gene="TBS1"
/locus_tag="YBR150C"
/product="Tbs1p"
/transcript_id="NM_001178498.1"
/db_xref="GI:296142813"
/db_xref="GeneID:852447"
CDS complement(541209..544493)
/gene="TBS1"
/locus_tag="YBR150C"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies; TBS1 has a paralog, HAL9, that
arose from the whole genome duplication"
/codon_start=1
/product="Tbs1p"
/protein_id="NP_009708.1"
/db_xref="GI:6319626"
/db_xref="SGD:S000000354"
/db_xref="GeneID:852447"
/translation="MNMDSGITSSHGSMDKTQKQSSEWAANQKHNQRVENTRVLMGPA
VPAMPPVPSNFPPVPTGTIMSPQLSPFPDHRLRHHPLAHMMPADKNFLAYNMESFKSR
VTKACDYCRKRKIRCTEIEPISGKCRNCIKYNKDCTFHFHEELKRRREEALNNKGNGK
SVKKPRLDKENKFKDENFDIAVRSRNTSSTDSSPKLHTNLSQEYIGVSAGKSASDKED
TWPDFVPIDRTVLEKIELNHTKVAGKVFVLEEICKNMKGTIEKLAEKSKIDVIDKEYM
KRPKRKQYSKALLTKQKMFHFRQNVLSHLTDEEFLSPINEMFTTTFKYSILQTKLVLD
FSFRSASSPSSDNILYPLPRLAIAKRLLKNIKCPSLASLLHIVDVDQCLQFADVHFDP
AKGRLTSSQAFLLNICLCLGATVTNFEEKQELVDEDNHETYYFEKFELWRLRSFTFLN
SVYYYHKLSVARADMTALKALLLLAKFAQQKISASSAVKVLSVAIKVALDLRLNLHST
YEDLELDEIIKRRRLWCYCFSTDKFFSVVLSRPPFLKEENTDVLTDESYVELFRDKIL
PNLSIKYDDSKLEGVKDIVSVVNLLANHLEYVPYIQSYFLSRLSLIESQIYYSCFSIR
TTLDDTLDEIIENVLENQKALDRMRDDLPTILSLENYKENMRILSLDSSKLDFEVSCC
TTILLHLRWYHQKITLSLFVISIIGDNLDQRESSRHDIAEIIRRSRLDFKRNCIEVLN
ILKDFEYYPTVQNEFLYFSLTTVFSMFLYLSEIMVNDEHAMETGYIIGLLRDTHTRML
GSEERCLSVHNLKWQTSLFFYTFFLRSTMEKFNLTSKYAKFYAFDSNYYEGVLNRLVK
HTRESKDDMVELLKTSFINKEKMAAFGSFVTEDQEKMEVSFNIFNEITIQDLNFLQFS
SIPKLWENKTLEPGEEYHHSNGTNTDNNETTGADDTDDNNNNNNNNNKNGNNSSSTIN
NNNNNYSNSNNNDNDNNINDDDDDDDDDDDDDDDDDDDDDNDDDYSNNGADDDEEDDD
YDRSLFPTGLASLLDASYPERTANDYRDENEQSNKLFEKIEGHLEHGVFFYDRDFFFK
NVCVKM"
gene 545028..545978
/gene="APD1"
/locus_tag="YBR151W"
/db_xref="GeneID:852448"
mRNA 545028..545978
/gene="APD1"
/locus_tag="YBR151W"
/product="Apd1p"
/transcript_id="NM_001178499.1"
/db_xref="GI:296142814"
/db_xref="GeneID:852448"
CDS 545028..545978
/gene="APD1"
/locus_tag="YBR151W"
/note="hypothetical protein, required for normal
localization of actin patches and for normal tolerance of
sodium ions and hydrogen peroxide; localizes to both
cytoplasm and nucleus"
/codon_start=1
/product="Apd1p"
/protein_id="NP_009709.1"
/db_xref="GI:6319627"
/db_xref="SGD:S000000355"
/db_xref="GeneID:852448"
/translation="MAFLNIFKQKRGDEASQLSAKGREEISQSIKICKSDDAANEHSC
SGDCKTEIEEGEQAFAKLKIEHETPLLNSSKTPKIHFVVPTSQIDWQHDACLEDPKSV
QYKISQWCDKNSAKFSNVGTGKTLNCAVSSLPKDIMDIDVMRGTKNNVLILPYFIWLN
DLRSDDVEATLDGLVPDLLDENISREKLLETRPNVAVARERAFVFICSHTTRDKRCGI
TAPYLKKVFDSKLQEHGLYRDNSDYRAEGVKIAFVNHVGGHKFAANVQIYLRNPNTLI
WLGRVTPTIVPSIVEHLIVPEEPTLPFPEKVRCIKKYQSW"
gene 546376..547251
/gene="SPP381"
/locus_tag="YBR152W"
/db_xref="GeneID:852449"
mRNA 546376..547251
/gene="SPP381"
/locus_tag="YBR152W"
/product="Spp381p"
/transcript_id="NM_001178500.3"
/db_xref="GI:398365112"
/db_xref="GeneID:852449"
CDS 546376..547251
/gene="SPP381"
/locus_tag="YBR152W"
/note="mRNA splicing factor, component of U4/U6.U5
tri-snRNP; interacts genetically and physically with
Prp38p"
/codon_start=1
/product="Spp381p"
/protein_id="NP_009710.3"
/db_xref="GI:398365113"
/db_xref="SGD:S000000356"
/db_xref="GeneID:852449"
/translation="MSFRHFKRRLDTSSADESSSADEEHPDQNVSLTEKSASLSHSDL
GGEILNGTGKNRTPNDGQESNESDGSPESDESPESEESSDNSDSSDSDDMRPLPRPLF
MKKKANNLQKATKIDQPWNAQDDARVLQTKKENMIKNIDKANQVAKNYETMKLRLNTN
YSTNEELIKQCLLLDDNDEVDSEKERQKWFERQNERKQKHRRIQLAKQRESEEYEAKR
FEAMQKGKDGNTKYDVILDKEKEKLDHKKQRSAEKVEKSHNNNRYKITRTKNVEFGDL
GKNSRDYEETEYSVI"
gene 547460..548194
/gene="RIB7"
/locus_tag="YBR153W"
/db_xref="GeneID:852450"
mRNA 547460..548194
/gene="RIB7"
/locus_tag="YBR153W"
/product="Rib7p"
/transcript_id="NM_001178501.3"
/db_xref="GI:398365116"
/db_xref="GeneID:852450"
CDS 547460..548194
/gene="RIB7"
/locus_tag="YBR153W"
/EC_number="1.1.1.193"
/note="Diaminohydroxyphoshoribosylaminopyrimidine
deaminase; catalyzes the second step of the riboflavin
biosynthesis pathway"
/codon_start=1
/product="Rib7p"
/protein_id="NP_009711.3"
/db_xref="GI:398365117"
/db_xref="SGD:S000000357"
/db_xref="GeneID:852450"
/translation="MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARV
SRGPGVRTTISHPETKTMTHYLRHHHDGILVGSGTVLADNPGLNCKWGPDPAANSPRP
IIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQHVDYAICPINDTTKLVD
WKKLFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSLIITIGSTFLGSSGTEVSPP
QTVNLKDMSWWKGITDVVLCARLADD"
gene complement(548362..549009)
/gene="RPB5"
/locus_tag="YBR154C"
/db_xref="GeneID:852451"
mRNA complement(548362..549009)
/gene="RPB5"
/locus_tag="YBR154C"
/product="Rpb5p"
/transcript_id="NM_001178502.1"
/db_xref="GI:296142817"
/db_xref="GeneID:852451"
CDS complement(548362..549009)
/gene="RPB5"
/locus_tag="YBR154C"
/note="RNA polymerase subunit ABC27, common to RNA
polymerases I, II, and III; contacts DNA and affects
transactivation"
/codon_start=1
/product="Rpb5p"
/protein_id="NP_009712.1"
/db_xref="GI:6319630"
/db_xref="SGD:S000000358"
/db_xref="GeneID:852451"
/translation="MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKA
KYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQE
KNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDE
KRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM"
gene 549771..550928
/gene="CNS1"
/locus_tag="YBR155W"
/db_xref="GeneID:852452"
mRNA 549771..550928
/gene="CNS1"
/locus_tag="YBR155W"
/product="Cns1p"
/transcript_id="NM_001178503.1"
/db_xref="GI:296142818"
/db_xref="GeneID:852452"
CDS 549771..550928
/gene="CNS1"
/locus_tag="YBR155W"
/note="TPR-containing co-chaperone; binds both Hsp82p
(Hsp90) and Ssa1p (Hsp70) and stimulates the ATPase
activity of SSA1, ts mutants reduce Hsp82p function while
over expression suppresses the phenotypes of an HSP82 ts
allele and a cpr7 deletion"
/codon_start=1
/product="Cns1p"
/protein_id="NP_009713.1"
/db_xref="GI:6319631"
/db_xref="SGD:S000000359"
/db_xref="GeneID:852452"
/translation="MSSVNANGGYTKPQKYVPGPGDPELPPQLSEFKDKTSDEILKEM
NRMPFFMTKLDETDGAGGENVELEALKALAYEGEPHEIAENFKKQGNELYKAKRFKDA
RELYSKGLAVECEDKSINESLYANRAACELELKNYRRCIEDCSKALTINPKNVKCYYR
TSKAFFQLNKLEEAKSAATFANQRIDPENKSILNMLSVIDRKEQELKAKEEKQQREAQ
ERENKKIMLESAMTLRNITNIKTHSPVELLNEGKIRLEDPMDFESQLIYPALIMYPTQ
DEFDFVGEVSELTTVQELVDLVLEGPQERFKKEGKENFTPKKVLVFMETKAGGLIKAG
KKLTFHDILKKESPDVPLFDNALKIYIVPKVESEGWISKWDKQKALERRSV"
gene complement(551104..553200)
/gene="SLI15"
/locus_tag="YBR156C"
/db_xref="GeneID:852453"
mRNA complement(551104..553200)
/gene="SLI15"
/locus_tag="YBR156C"
/product="Sli15p"
/transcript_id="NM_001178504.3"
/db_xref="GI:398365136"
/db_xref="GeneID:852453"
CDS complement(551104..553200)
/gene="SLI15"
/locus_tag="YBR156C"
/note="Subunit of the conserved chromosomal passenger
complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates
kinetochore-microtubule attachments, activation of the
spindle tension checkpoint, and mitotic spindle
disassembly"
/codon_start=1
/product="Sli15p"
/protein_id="NP_009714.3"
/db_xref="GI:398365137"
/db_xref="SGD:S000000360"
/db_xref="GeneID:852453"
/translation="MDWAIKAARKKTQRKPGSTRSIIETLDDLNNLTTDAHSEINQRL
YESSEWLRNNVYMNTLKYEDKKMEESLISPENTHNKMDVEFPKMKGEYELSNSQNDAA
KDVTKTPRNGLHNDKSITPKSLRRKEVTEGMNRFSIHDTNKSPVEPLNSVKVDANESE
KSSPWSPYKVEKVLRESSKTSESPINTKRFDNQTWAAKEEMENEPILQALKKAESVKV
KPPPNSGIARSQRRSNMFVPLPNKDPLIIQHIPPTKSSGSIPKVRTVKESPIAFKKKS
TINSPAIRAVENSDTAGSTKASSVFDRLSSIPTKSFENKISRGNVGHKYSSSSIDLTG
SPMKKVSQKFKSINSTDTDMQEALRDIFSVKNKITKNNSPKGKNSRKSSIPRFDKTSL
KLTTHKKLAIIAEQKKKSKHSSDVHKTGSRPHSISPTKISVDSSSPSKEVKNYYQSPV
RGYLRPTKASISPNKNKNLTTSQTPHRLKIKEKTLRKLSPNIADISKPESRKSKNYRL
TNLQLLPPAEAERDDLKKKFDKRLSGIMRSQQEHHRRKQEKQKRMSHLEQDLKKQTSF
SNDYKDIRLKESLAPFDNHVRDTINKNTAFSTDNILATINTVDHREIIGNVTPKIASV
NDSLPEINTDSEDEASVTLAAWAKSPYLQEQLIRQQDINPQTIFGPIPPLHTDEIFPN
PRLNRLKPRQIVPKRS"
gene complement(553543..554310)
/gene="ICS2"
/locus_tag="YBR157C"
/db_xref="GeneID:852454"
mRNA complement(553543..554310)
/gene="ICS2"
/locus_tag="YBR157C"
/product="Ics2p"
/transcript_id="NM_001178505.3"
/db_xref="GI:398365148"
/db_xref="GeneID:852454"
CDS complement(553543..554310)
/gene="ICS2"
/locus_tag="YBR157C"
/note="hypothetical protein; null mutation does not confer
any obvious defects in growth, spore germination,
viability, or carbohydrate utilization"
/codon_start=1
/product="Ics2p"
/protein_id="NP_009715.4"
/db_xref="GI:398365149"
/db_xref="SGD:S000000361"
/db_xref="GeneID:852454"
/translation="MGKFEQKERERISTFSFPTTGSQSSTSIKSLGSPLYGRFSSLSS
TESQFDSSKQPHEYEKSFYFEESQGEALFNKLKTYSFPGDKDGVKTRRNSSICPRKPN
AVSPLRVESNELSSHSHSRSLSHELTKPSGRRKSYHRKSHAISFSRSCKPNFIDGYDS
NSSIGVNSRKTSLASSFLDKEYHSSPDTSYTHQMSPKNTIMNTNEQLRRNASGRFGSL
KEFAEKNQINIEGKIFAHKVETGDILQPLIDLDIDNK"
gene 556549..558198
/gene="AMN1"
/locus_tag="YBR158W"
/gene_synonym="CST13; ICS4"
/db_xref="GeneID:852455"
mRNA 556549..558198
/gene="AMN1"
/locus_tag="YBR158W"
/gene_synonym="CST13; ICS4"
/product="Amn1p"
/transcript_id="NM_001178506.1"
/db_xref="GI:296142821"
/db_xref="GeneID:852455"
CDS 556549..558198
/gene="AMN1"
/locus_tag="YBR158W"
/gene_synonym="CST13; ICS4"
/note="Protein required for daughter cell separation,
multiple mitotic checkpoints, and chromosome stability;
contains 12 degenerate leucine-rich repeat motifs;
expression is induced by the Mitotic Exit Network (MEN)"
/codon_start=1
/product="Amn1p"
/protein_id="NP_009716.1"
/db_xref="GI:6319634"
/db_xref="SGD:S000000362"
/db_xref="GeneID:852455"
/translation="MKLERVSSNGSFKRGRDIQSLESPCTRPLKKMSPSPSFTSLKME
KPFKDIVRKYGGHLHQSSYNPGSSKVELVRPDLSLKTDQSFLQSSVQTTPNKKSCNEY
LSTPEATPLKNTATENAWATSRVVSASSLSIVTPTEIKNILVDEFSELKLGQPLTAQH
QRSHAVFEIPEIVENIIKMIVSLESANIPKERPCLRRNPQSYEHSLLMYKDEERAKKA
WSAAQQLRDPPLVGHKEKKQGALFSCMMVNRLWLNVTRPFLFKSLHFKSVHNFKEFLR
TSQETTQVMRPSHFILHKLHQVTQPDIERLSRMECQNLKWLEFYVCPRITPPLSWFDN
LHKLEKLIIPGNKNIDDNFLLRLSQSIPNLKHLVLRACDNVSDSGVVCIALNCPKLKT
FNIGRHRRGNLITSVSLVALGKYTQVETVGFAGCDVDDAGIWEFARLNGKNVERLSLN
SCRLLTDYSLPILFALNSFPNLAVLEIRNLDKITDVRHFVKYNLWKKSLDAPILIEAC
ERITKLIDQEENRVKRINSLVALKDMTAWVNADDEIENNVD"
gene 558685..559728
/gene="IFA38"
/locus_tag="YBR159W"
/db_xref="GeneID:852456"
mRNA 558685..559728
/gene="IFA38"
/locus_tag="YBR159W"
/product="ketoreductase"
/transcript_id="NM_001178507.1"
/db_xref="GI:296142822"
/db_xref="GeneID:852456"
CDS 558685..559728
/gene="IFA38"
/locus_tag="YBR159W"
/EC_number="1.-.-.-"
/note="Microsomal beta-keto-reductase; contains oleate
response element (ORE) sequence in the promoter region;
mutants exhibit reduced VLCFA synthesis, accumulate high
levels of dihydrosphingosine, phytosphingosine and
medium-chain ceramides"
/codon_start=1
/product="ketoreductase"
/protein_id="NP_009717.1"
/db_xref="GI:6319635"
/db_xref="SGD:S000000363"
/db_xref="GeneID:852456"
/translation="MTFMQQLQEAGERFRCINGLLWVVFGLGVLKCTTLSLRFLALIF
DLFLLPAVNFDKYGAKTGKYCAITGASDGIGKEFARQMAKRGFNLVLISRTQSKLEAL
QKELEDQHHVVVKILAIDIAEDKESNYESIKELCAQLPITVLVNNVGQSHSIPVPFLE
TEEKELRNIITINNTATLLITQIIAPKIVETVKAENKKSGTRGLILTMGSFGGLIPTP
LLATYSGSKSFLQGWSNSLAGELSKDAIDVELIISYLVTSSMSKIRRSSLMIPNPQQF
VKSTLRSVGRRCGSQERYATMTPYWAHAVYQFVITETFGVYSKIVNSINYSFHKSIRI
RALKKAARQVKKE"
gene 560078..560974
/gene="CDC28"
/locus_tag="YBR160W"
/gene_synonym="CDK1; HSL5; SRM5"
/db_xref="GeneID:852457"
mRNA 560078..560974
/gene="CDC28"
/locus_tag="YBR160W"
/gene_synonym="CDK1; HSL5; SRM5"
/product="Cdc28p"
/transcript_id="NM_001178508.3"
/db_xref="GI:398365174"
/db_xref="GeneID:852457"
CDS 560078..560974
/gene="CDC28"
/locus_tag="YBR160W"
/gene_synonym="CDK1; HSL5; SRM5"
/EC_number="2.7.11.22"
/note="Catalytic subunit of the main cell cycle
cyclin-dependent kinase (CDK); alternately associates with
G1 cyclins (CLNs) and G2/M cyclins (CLBs) which direct the
CDK to specific substrates; involved in modulating
membrane trafficking dynamics; protein abundance increases
in response to DNA replication stress"
/codon_start=1
/product="Cdc28p"
/protein_id="NP_009718.3"
/db_xref="GI:398365175"
/db_xref="SGD:S000000364"
/db_xref="GeneID:852457"
/translation="MSGELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRL
ESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGI
PKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARA
FGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEI
DQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLL
AYDPINRISARRAAIHPYFQES"
gene 561634..562764
/gene="CSH1"
/locus_tag="YBR161W"
/db_xref="GeneID:852458"
mRNA 561634..562764
/gene="CSH1"
/locus_tag="YBR161W"
/product="mannosylinositol phosphorylceramide synthase
catalytic subunit CSH1"
/transcript_id="NM_001178509.3"
/db_xref="GI:398365182"
/db_xref="GeneID:852458"
CDS 561634..562764
/gene="CSH1"
/locus_tag="YBR161W"
/EC_number="2.-.-.-"
/note="Mannosylinositol phosphorylceramide (MIPC) synthase
catalytic subunit; forms a complex with regulatory subunit
Csg2p; function in sphingolipid biosynthesis is
overlapping with that of Sur1p; CSH1 has a paralog, SUR1,
that arose from the whole genome duplication"
/codon_start=1
/product="mannosylinositol phosphorylceramide synthase
catalytic subunit CSH1"
/protein_id="NP_009719.3"
/db_xref="GI:398365183"
/db_xref="SGD:S000000365"
/db_xref="GeneID:852458"
/translation="MKKELKILIIANIALLISIIHYTFDLLTLCIDDTSKDALTDEQL
NPPNGFNSTFYESPPQLIPKIIHQTYKTNDIPEQWVKGRQKCIDLHPDYTYILWTDEM
SDTFIKQEYPWFLDTFRSYEYPIERADAIRYFILSHYGGIYIDLDDGCERRLDPLLKV
PAFLRKTSPTGVSNDVMGSVPRHPFFLKVIKSLKHYKKNWYIPYMTIMGSTGPLFISV
VWKQYKRWSNTAENGAVRILQPADYKMHNNSFFSISKGSSWHTGDANFMKTLENHILS
CVVTGFIFGFFILYGEFTFYTWLCSGPFNNKRYYIQWLSDKFKLHKWKLTSSYKNKEK
RRNPTRHEYNSRGKRLRKDSNIPYDSVFLDIEKNHAKFTDLT"
gene complement(563203..564570)
/gene="TOS1"
/locus_tag="YBR162C"
/db_xref="GeneID:852459"
mRNA complement(563203..564570)
/gene="TOS1"
/locus_tag="YBR162C"
/product="Tos1p"
/transcript_id="NM_001178510.1"
/db_xref="GI:296142825"
/db_xref="GeneID:852459"
CDS complement(563203..564570)
/gene="TOS1"
/locus_tag="YBR162C"
/note="Covalently-bound cell wall hypothetical protein;
identified as a cell cycle regulated SBF target gene;
deletion mutants are highly resistant to treatment with
beta-1,3-glucanase; has sequence similarity to YJL171C"
/codon_start=1
/product="Tos1p"
/protein_id="NP_009720.1"
/db_xref="GI:6319638"
/db_xref="SGD:S000000366"
/db_xref="GeneID:852459"
/translation="MLQKLSMTALVGLFSSVVSLVNADCTYSGGNYYCAQTDAIIYSN
VGLSATYQDVTNMDESSCACTQADFTASGSLAPFNEELSVHFRGPIELLQFGVYYPNG
ESNALKKRSEKQSIESCKEGEAVVSRHKHQHKRDVAVEYVQVTSTVYVDSNGQTVTAD
STNTVVGPAVPSSYTKDSTVLSSSAQAVETSESQSSISSSKTTSSAAAASSSSSSSSN
TNGDWSRGSYFVPGSTSNCTFMNNQGGTAGSGVWSSCFGNSISFAASDGVSGAASAQA
LGDVTIKSGNEFMIFSGEECSGNNGDCGYYREGIPAYHGFGGADKIFVFEFSMPSDTS
GSAYNQDMPAIWLLNAKIPRTLQYGDASCSCWKTGCGEMDLFEILTAGSDKLISHIHD
GQDGGTQDYFERPTDGTLKAAVIFNSSDKTIHIIEVDESFDATLSDDVVDQWLSKSGS
SAALP"
gene 565231..565428
/gene="YSY6"
/locus_tag="YBR162W-A"
/db_xref="GeneID:852460"
mRNA 565231..565428
/gene="YSY6"
/locus_tag="YBR162W-A"
/product="Ysy6p"
/transcript_id="NM_001180059.1"
/db_xref="GI:296142826"
/db_xref="GeneID:852460"
CDS 565231..565428
/gene="YSY6"
/locus_tag="YBR162W-A"
/note="Protein whose expression suppresses a secretory
pathway mutation in E. coli; has similarity to the
mammalian RAMP4 protein involved in secretion"
/codon_start=1
/product="Ysy6p"
/protein_id="NP_009721.1"
/db_xref="GI:6319639"
/db_xref="SGD:S000002158"
/db_xref="GeneID:852460"
/translation="MAVQTPRQRLANAKFNKNNEKYRKYGKKKEGKTEKTAPVISKTW
LGILLFLLVGGGVLQLISYIL"
gene 565723..567480
/gene="EXO5"
/locus_tag="YBR163W"
/gene_synonym="DEM1"
/db_xref="GeneID:852461"
mRNA 565723..567480
/gene="EXO5"
/locus_tag="YBR163W"
/gene_synonym="DEM1"
/product="Exo5p"
/transcript_id="NM_001178511.3"
/db_xref="GI:398365198"
/db_xref="GeneID:852461"
CDS 565723..567480
/gene="EXO5"
/locus_tag="YBR163W"
/gene_synonym="DEM1"
/note="Mitochondrial 5'-3' exonuclease and sliding
exonuclease, required for mitochondrial genome
maintenance; distantly related to the RecB nuclease domain
of bacterial RecBCD recombinases; may be regulated by the
transcription factor Ace2"
/codon_start=1
/product="Exo5p"
/protein_id="NP_009722.3"
/db_xref="GI:398365199"
/db_xref="SGD:S000000367"
/db_xref="GeneID:852461"
/translation="MLGRALINKYGFLIHPRRFVHLNDKSLDGTFILPSKKNHMYDVP
TNDPSGILNASDIDRINNLPFFDNTSPTKETNTKEGALLSEKLASVKELFGEDPENPS
FINYRFPRGLENPYFDIQVNQLKKKRLSVTQLCTTQNWCELRNFYDFYSQNLSNQLLN
LKFQVQKGKKIHKSLEDETHPELNQYKSFTHNFLALTKLSMDIDNDMDALLDNWFNSI
NRLVSLFTKGDGHAREIVCHGFINLEDGKLVEHLLNSDSKTKENVIISGVIDHLTLRN
RHNHQVQKGAAHLDTEYQSWGNILTNLLSNLKELKSNNEIVISDIKTRSVPKIPSIES
VIESSKLQTMYYKFFFSHLSQDMTQTYHSFLINAQRRGLDVDAPINPTKILTFILTNP
LFANDVKNLLYGLPINHSAFDNDAKGSNTFDMTAFNDLLDRGPTSFNVPIEQDEDSSE
STKCVSLRDYGHFYTKWKTPLTLKYFAARLSQIYFIVGNLVSNDLMIEYYYHNDNFHN
IIFPYDPLKLGTHAHDSAMVWFGGRDMHPIEPTQKNFNTYCKFCDYRHVCSWKNKNEL
KLIDLGKELKKIILESSMK"
gene complement(567875..568426)
/gene="ARL1"
/locus_tag="YBR164C"
/gene_synonym="DLP2"
/db_xref="GeneID:852462"
mRNA complement(567875..568426)
/gene="ARL1"
/locus_tag="YBR164C"
/gene_synonym="DLP2"
/product="Arl1p"
/transcript_id="NM_001178512.3"
/db_xref="GI:398365212"
/db_xref="GeneID:852462"
CDS complement(567875..568426)
/gene="ARL1"
/locus_tag="YBR164C"
/gene_synonym="DLP2"
/note="Soluble GTPase with a role in regulation of
membrane traffic; regulates potassium influx; G protein of
the Ras superfamily, similar to ADP-ribosylation factor"
/codon_start=1
/product="Arl1p"
/protein_id="NP_009723.3"
/db_xref="GI:398365213"
/db_xref="SGD:S000000368"
/db_xref="GeneID:852462"
/translation="MGNIFSSMFDKLWGSNKELRILILGLDGAGKTTILYRLQIGEVV
TTKPTIGFNVETLSYKNLKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTDKDRMS
TASKELHLMLQEEELQDAALLVFANKQDQPGALSASEVSKELNLVELKDRSWSIVASS
AIKGEGITEGLDWLIDVIKEEQL"
gene 568852..569685
/gene="UBS1"
/locus_tag="YBR165W"
/db_xref="GeneID:852463"
mRNA 568852..569685
/gene="UBS1"
/locus_tag="YBR165W"
/product="Ubs1p"
/transcript_id="NM_001178513.1"
/db_xref="GI:296142829"
/db_xref="GeneID:852463"
CDS 568852..569685
/gene="UBS1"
/locus_tag="YBR165W"
/note="Ubiquitin-conjugating enzyme suppressor that
functions as a general positive regulator of Cdc34p
activity; nuclear protein that may represent a link
between nucleocytoplasmic transport and ubiquitin ligase
activity"
/codon_start=1
/product="Ubs1p"
/protein_id="NP_009724.1"
/db_xref="GI:6319642"
/db_xref="SGD:S000000369"
/db_xref="GeneID:852463"
/translation="MAYSLTRKLLKDWKYFMRHPEKTQGLFHVRPHDSDLHLWHVVMY
EPRTSLEVYLLLYIGGNDQDPYIIMKCLSPNCCFPINRTVSMTHLNYLLLKDLGLQDL
LFHIWQPLFHIQATEDLQYSPSTVKFNRAWNRIIYKDFKSYFPELIGTLQPGDYSIVK
SYSKNHNISNSNGGSVNEFMSSYNAQSHTFHAQDNSKNPYTNSSIGKSSMLSTLNNNN
VNKRTHDYNAIDFMTKNLLACDDDSIHPVVSSKRSRTLACPDETNDNRGSEHYTKRKK
I"
gene complement(569842..571200)
/gene="TYR1"
/locus_tag="YBR166C"
/db_xref="GeneID:852464"
mRNA complement(569842..571200)
/gene="TYR1"
/locus_tag="YBR166C"
/product="pprephenate dehydrogenase (NADP(+))"
/transcript_id="NM_001178514.1"
/db_xref="GI:296142830"
/db_xref="GeneID:852464"
CDS complement(569842..571200)
/gene="TYR1"
/locus_tag="YBR166C"
/EC_number="1.3.1.13"
/note="Prephenate dehydrogenase involved in tyrosine
biosynthesis, expression is dependent on phenylalanine
levels"
/codon_start=1
/product="pprephenate dehydrogenase (NADP(+))"
/protein_id="NP_009725.1"
/db_xref="GI:6319643"
/db_xref="SGD:S000000370"
/db_xref="GeneID:852464"
/translation="MVSEDKIEQWKATKVIGIIGLGDMGLLYANKFTDAGWGVICCDR
EEYYDELKEKYASAKFELVKNGHLVSRQSDYIIYSVEASNISKIVATYGPSSKVGTIV
GGQTSCKLPEIEAFEKYLPKDCDIITVHSLHGPKVNTEGQPLVIINHRSQYPESFEFV
NSVMACLKSKQVYLTYEEHDKITADTQAVTHAAFLSMGSAWAKIKIYPWTLGVNKWYG
GLENVKVNISLRIYSNKWHVYAGLAITNPSAHQQILQYATSATELFSLMIDNKEQELT
DRLLKAKQFVFGKHTGLLLLDDTILEKYSLSKSSIGNSNNCKPVPNSHLSLLAIVDSW
FQLGIDPYDHMICSTPLFRIFLGVSEYLFLKPGLLEQTIDAAIHDKSFIKDDLEFVIS
AREWSSVVSFANFDIYKKQFQSVQKFFEPMLPEANLIGNEMIKTILSHSSDRSAAEKR
NT"
gene complement(571468..571890)
/gene="POP7"
/locus_tag="YBR167C"
/gene_synonym="RPP2"
/db_xref="GeneID:852465"
mRNA complement(571468..571890)
/gene="POP7"
/locus_tag="YBR167C"
/gene_synonym="RPP2"
/product="Pop7p"
/transcript_id="NM_001178515.3"
/db_xref="GI:398365234"
/db_xref="GeneID:852465"
CDS complement(571468..571890)
/gene="POP7"
/locus_tag="YBR167C"
/gene_synonym="RPP2"
/EC_number="3.1.26.5"
/note="Subunit of both RNase MRP and nuclear RNase P;
RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves
tRNA precursors to generate mature 5' ends and facilitates
turnover of nuclear RNAs"
/codon_start=1
/product="Pop7p"
/protein_id="NP_009726.3"
/db_xref="GI:398365235"
/db_xref="SGD:S000000371"
/db_xref="GeneID:852465"
/translation="MALKKNTHNKSTKRVTKHPSLKTLTHKQIHTTIFVKSTTPYVSA
LKRINKFLDSVHKQGSSYVAVLGMGKAVEKTLALGCHFQDQKNKKIEVYTKTIEVLDE
VITEGQADIDMESDVEDDDKETQLKKRAVSGVELRIYV"
gene 572371..573612
/gene="PEX32"
/locus_tag="YBR168W"
/db_xref="GeneID:852466"
mRNA 572371..573612
/gene="PEX32"
/locus_tag="YBR168W"
/product="Pex32p"
/transcript_id="NM_001178516.3"
/db_xref="GI:398365240"
/db_xref="GeneID:852466"
CDS 572371..573612
/gene="PEX32"
/locus_tag="YBR168W"
/note="Peroxisomal integral membrane protein, involved in
negative regulation of peroxisome size; partially
functionally redundant with Pex31p; genetic interactions
suggest action at a step downstream of steps mediated by
Pex28p and Pex29p"
/codon_start=1
/product="Pex32p"
/protein_id="NP_009727.3"
/db_xref="GI:398365241"
/db_xref="SGD:S000000372"
/db_xref="GeneID:852466"
/translation="MDTNSKTKVQTENKKIKAKFIHNHGQKPSLIQITPPMISSTLFH
AYPLLLIFDNALANIMWLSDDKCLTFIYLTSIWLTISFFIPVETEASHFLPFTKILRL
WLGIISGAFLFLSFMYYIVSLIASLRDTEPPTLDEIVVLLESVLDKLEVLRNELNVWK
KLKLSFDGVNKECSGKRLFCRLFLFGTIFQIIIMRYISPGTYTRFFIITGLIYNTSSF
QATLRLLWRFTAVRNFYYLGIESFKISSFLPKHLKMEQIIPLSQGRAITVPLVEVLPK
LLRDKKGDDHIHILQLLLNEQKDNFGNEDLKILEIEVYENQRRWYQNKNWSTKLLPYE
RQNYCIEIKNTDGTLTMRSCLPPDGLGEEELPNNWHWINDNWDGTDWIYSDSAWKEIG
QYSSLESFTRSRKWKRRLFHL"
gene complement(573915..575996)
/gene="SSE2"
/locus_tag="YBR169C"
/db_xref="GeneID:852467"
mRNA complement(573915..575996)
/gene="SSE2"
/locus_tag="YBR169C"
/product="Sse2p"
/transcript_id="NM_001178517.1"
/db_xref="GI:296142833"
/db_xref="GeneID:852467"
CDS complement(573915..575996)
/gene="SSE2"
/locus_tag="YBR169C"
/note="Member of the heat shock protein 70 (HSP70) family;
may be involved in protein folding; localized to the
cytoplasm; highly homologous to the heat shock protein
Sse1p"
/codon_start=1
/product="Sse2p"
/protein_id="NP_009728.1"
/db_xref="GI:6319646"
/db_xref="SGD:S000000373"
/db_xref="GeneID:852467"
/translation="MSTPFGLDLGNNNSVLAVARNRGIDVVVNEVSNRSTPSLVGFGP
RNRYLGESGKTKQTSNVKNTVENLKRIIGLKFKDPEFDIENKFFTSKLVQLKNGKVGV
EVEFGGKTHVFSATQLTAMFIDKVKHTVQEETKSSITDVCLAVPVWYSEEQRYNIADA
ARIAGLNPVRIVNDVTAAAVSYGVFKNDLPGPEEKPRIIGLVDIGHSTYTCSIMAFRK
GEMKVLGTAYDKHFGGRDFDRAITEHFADQFKDKYKIDIRKNPKAYNRILIAAEKLKK
VLSANTTAPFSVESVMDDIDVSSQLSREELEELVEPLLKRVTYPITNALAQAKLTVND
IDFVEIIGGTTRIPVLKKSISDVFGKPLSSTLNQDEAVAKGAAFICAIHSPTLRVRPF
KFEDIDPYSVSYTWDKQVDDEDRLEVFPANSSYPSTKLITLHRTGDFSMKAVYTHPSK
LPKGTSTTIAKWSFTGVKVPKDQDFIPVKVKLRCDPSGLHIIENAYTTEDITVQEPVP
LPEDAPEDAEPQFKEVTKTIKKDVLGMTAKTFALNPVELNDLIEKENELRNQDKLVAE
TEDRKNALEEYIYTLRAKLDDEYSDFASDAEKEKLKNMLATTENWLYGDGDDSTKAKY
IAKYEELASLGNIIRGRYLAKEEEKRQALRANQETSKMNDIAEKLAEQRRARAASDDS
DDNNDENMDLD"
gene complement(576344..578086)
/gene="NPL4"
/locus_tag="YBR170C"
/gene_synonym="HRD4"
/db_xref="GeneID:852468"
mRNA complement(576344..578086)
/gene="NPL4"
/locus_tag="YBR170C"
/gene_synonym="HRD4"
/product="Npl4p"
/transcript_id="NM_001178518.1"
/db_xref="GI:296142834"
/db_xref="GeneID:852468"
CDS complement(576344..578086)
/gene="NPL4"
/locus_tag="YBR170C"
/gene_synonym="HRD4"
/note="Substrate-recruiting cofactor of the
Cdc48p-Npl4p-Ufd1p segregase; assists Cdc48p in the
dislocation of misfolded, polyubiquitinated ERAD
substrates that are subsequently delivered to the
proteasome for degradation; also involved in the regulated
destruction of resident ER membrane proteins, such as
HMG-CoA reductase (Hmg1/2p) and cytoplasmic proteins
(Fbp1p); role in mobilizing membrane bound transcription
factors by regulated ubiquitin/proteasome-dependent
processing (RUP)"
/codon_start=1
/product="Npl4p"
/protein_id="NP_009729.1"
/db_xref="GI:6319647"
/db_xref="SGD:S000000374"
/db_xref="GeneID:852468"
/translation="MLIRFRSKNGTHRVSCQENDLFGTVIEKLVGNLDPNADVDTFTV
CEKPGQGIHAVSELADRTVMDLGLKHGDMLILNYSDKPANEKDGVNVEIGSVGIDSKG
IRQHRYGPLRIKELAVDEELEKEDGLIPRQKSKLCKHGDRGMCEYCSPLPPWDKEYHE
KNKIKHISFHSYLKKLNENANKKENGSSYISPLSEPDFRINKRCHNGHEPWPRGICSK
CQPSAITLQQQEFRMVDHVEFQKSEIINEFIQAWRYTGMQRFGYMYGSYSKYDNTPLG
IKAVVEAIYEPPQHDEQDGLTMDVEQVKNEMLQIDRQAQEMGLSRIGLIFTDLSDAGA
GDGSVFCKRHKDSFFLSSLEVIMAARHQTRHPNVSKYSEQGFFSSKFVTCVISGNLEG
EIDISSYQVSTEAEALVTADMISGSTFPSMAYINDTTDERYVPEIFYMKSNEYGITVK
ENAKPAFPVDYLLVTLTHGFPNTDTETNSKFVSSTGFPWSNRQAMGQSQDYQELKKYL
FNVASSGDFNLLHEKISNFHLLLYINSLQILSPDEWKLLIESAVKNEWEESLLKLVSS
AGWQTLVMILQESG"
gene 578364..578984
/gene="SEC66"
/locus_tag="YBR171W"
/gene_synonym="HSS1; SEC71"
/db_xref="GeneID:852469"
mRNA 578364..578984
/gene="SEC66"
/locus_tag="YBR171W"
/gene_synonym="HSS1; SEC71"
/product="Sec66p"
/transcript_id="NM_001178519.3"
/db_xref="GI:398365264"
/db_xref="GeneID:852469"
CDS 578364..578984
/gene="SEC66"
/locus_tag="YBR171W"
/gene_synonym="HSS1; SEC71"
/note="Non-essential subunit of Sec63 complex (Sec63p,
Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP
and Lhs1p forms a channel competent for SRP-dependent and
post-translational SRP-independent protein targeting and
import into the ER"
/codon_start=1
/product="Sec66p"
/protein_id="NP_009730.3"
/db_xref="GI:398365265"
/db_xref="SGD:S000000375"
/db_xref="GeneID:852469"
/translation="MSEFNETKFSNNGTFFETEEPIVETKSISVYTPLIYVFILVVSL
VMFASSYRKKQAKKISEQPSIFDENDAHDLYFQIKEMSENEKIHEKVLKAALLNRGAE
SVRRSLKLKELAPQINLLYKNGSIGEDYWKRFETEVKLIELEFKDTLQEAERLQPGWV
QLFVMVCKEICFNQALSRRYQSILKRKEVCIKEWELKINNDGRLVN"
gene complement(579150..581372)
/gene="SMY2"
/locus_tag="YBR172C"
/db_xref="GeneID:852470"
mRNA complement(579150..581372)
/gene="SMY2"
/locus_tag="YBR172C"
/product="Smy2p"
/transcript_id="NM_001178520.3"
/db_xref="GI:398365268"
/db_xref="GeneID:852470"
CDS complement(579150..581372)
/gene="SMY2"
/locus_tag="YBR172C"
/note="hypothetical protein involved in COPII vesicle
formation; interacts with the Sec23p/Sec24p subcomplex;
overexpression suppresses the temperature sensitivity of a
myo2 mutant; has similarity to S. pombe Mpd2"
/codon_start=1
/product="Smy2p"
/protein_id="NP_009731.4"
/db_xref="GI:398365269"
/db_xref="SGD:S000000376"
/db_xref="GeneID:852470"
/translation="MIAPDSQRLFGSFDEQFKDLKLDSVDTENNNTHGVSTILDSSPA
SVNNNTNGAVAASVNTVPGSTFRSNTPLLGGRHPLSRTSSLIDSIGIQRAASPFSSMK
EPFIPQSSGVMSSSFWHGDHPESRVSTPVQQHPLLQRNESSSSFSYAANLGVNLSTHS
LAVDITPLSTPTAAQSHVNLFPSSDIPPNMSMNGMSQLPAPVSVESSWRYIDTQGQIH
GPFTTQMMSQWYIGGYFASTLQISRLGSTPETLGINDIFITLGELMTKLEKYDTDPFT
TFDKLHVQTTSSDSINLNLAPYASGVAATGTIKATENDIFKPLTHDNIWDMDGGTTSK
GVDIKLASATTISQTDESHKQEYKSTTMLEKGKKEKSESVAKALLDEQEKRNRELKRK
EEARLSKKQKQKEDDLLKKQKEQKEQKEKEALEAEKQKKSEKTKKDTQTQTEGFKTSK
DLPSLNSSSANPAPWASKVKVNNAIETSIKNGVSSTGKKKGEPLGLQQRNSKEEKQKE
ELKSVLNWANKSSLPSNQTIDIKSQFQKSPKGMKESSPLKELEDPNFIEEQKKLWEKV
QSSSKQVKSTSSASTTTSSWTTVTSKGKAPIGTVVSPYSKTNTSLNSSLTAKTSTTST
TTTFASMNNVSPRQEFIKWCKSQMKLNSGITNNNVLELLLSLPTGPESKELIQETIYA
NSDVMDGRRFATEFIKRRVACEKQGDDPLSWNEALALSGNDDDGWEFQVVSKKKGRKH
"
gene complement(581726..582172)
/gene="UMP1"
/locus_tag="YBR173C"
/gene_synonym="RNS2"
/db_xref="GeneID:852471"
mRNA complement(581726..582172)
/gene="UMP1"
/locus_tag="YBR173C"
/gene_synonym="RNS2"
/product="Ump1p"
/transcript_id="NM_001178521.1"
/db_xref="GI:296142837"
/db_xref="GeneID:852471"
CDS complement(581726..582172)
/gene="UMP1"
/locus_tag="YBR173C"
/gene_synonym="RNS2"
/note="Short-lived chaperone required for correct
maturation of the 20S proteasome; may inhibit premature
dimerization of proteasome half-mers; degraded by
proteasome upon completion of its assembly"
/codon_start=1
/product="Ump1p"
/protein_id="NP_009732.1"
/db_xref="GI:6319650"
/db_xref="SGD:S000000377"
/db_xref="GeneID:852471"
/translation="MNIVPQDTFKSQVSTDQDKSVLSSAVPSLPDTLRQQEGGAVPLS
TQLNDRHPLESTLKNWETTQRQRQMEQYRQIFGIAEPMKRTMEMEIVNRTDFNPLSTN
GSIHRDILLNKECSIDWEDVYPGTGLQASTMVGDDVHSKIEKQLGI"
gene 582408..583355
/gene="SWD3"
/locus_tag="YBR175W"
/gene_synonym="CPS30; SAF35"
/db_xref="GeneID:852472"
mRNA 582408..583355
/gene="SWD3"
/locus_tag="YBR175W"
/gene_synonym="CPS30; SAF35"
/product="Swd3p"
/transcript_id="NM_001178523.1"
/db_xref="GI:296142838"
/db_xref="GeneID:852472"
CDS 582408..583355
/gene="SWD3"
/locus_tag="YBR175W"
/gene_synonym="CPS30; SAF35"
/note="Essential subunit of the COMPASS (Set1C) complex,
which methylates histone H3 on lysine 4 and is required in
transcriptional silencing near telomeres; WD40 beta
propeller superfamily member and ortholog of mammalian
WDR5"
/codon_start=1
/product="Swd3p"
/protein_id="NP_009734.1"
/db_xref="GI:6319651"
/db_xref="SGD:S000000379"
/db_xref="GeneID:852472"
/translation="MFQFVTPVGTQNGLKATCAKISPDGQFLAITQGLNILIYDINRR
TVSQTLVTSHARPFSELCWSPDGQCIATASDDFSVEIIHLSYGLLHTFIGHTAPVISL
TFNRKGNLLFTSSMDESIKIWDTLNGSLMKTISAHSEAVVSVDVPMNDSSILSSGSYD
GLIRIFDAETGHCLKTLTYDKDWKRENGVVPISQVKFSENARYLLVKSLDGVVKIWDC
IGGCVVRTFQVQPLEKGVLHHSCGMDFLNPEDGSTPLVISGYENGDIYCWNSDTKSLL
QLLDGSLYHHSSPVMSIHCFGNIMCSLALNGDCCLWRWV"
gene 583720..584658
/gene="ECM31"
/locus_tag="YBR176W"
/db_xref="GeneID:852474"
mRNA 583720..584658
/gene="ECM31"
/locus_tag="YBR176W"
/product="3-methyl-2-oxobutanoate
hydroxymethyltransferase"
/transcript_id="NM_001178524.3"
/db_xref="GI:398365288"
/db_xref="GeneID:852474"
CDS 583720..584658
/gene="ECM31"
/locus_tag="YBR176W"
/EC_number="2.1.2.11"
/note="Ketopantoate hydroxymethyltransferase, required for
pantothenic acid biosynthesis, converts 2-oxoisovalerate
into 2-dehydropantoate"
/codon_start=1
/product="3-methyl-2-oxobutanoate
hydroxymethyltransferase"
/protein_id="NP_009735.3"
/db_xref="GI:398365289"
/db_xref="SGD:S000000380"
/db_xref="GeneID:852474"
/translation="MNIMKRQLCTSSKRFFSTAKNVVKYNTIQDIRNKYFTGTPLSMC
TAYDFITATWVNKANCDLLLVGDSLAMTSLGYDSTITLSLNEFKYHVASVCRAEGSSM
VVVDMPFGTFESGISDGLKNAIDIMKLDSKVTSVKVEVGSYTKDKYAMKFIEELCSRG
IPVMAHIGLTPQKVHSLGGYKVQGSKSLLQMQELYETAMQLQKIGCWSILIECVPHKM
AQFITSKLSVPTIGIGAGNGTSGQVLVISDLLGMQGDSVPKFVKQAVNMTDIATQGLK
EYIASVEDRTFPERGTHTFKVKEDLWNEFLSSINEK"
gene complement(584807..586162)
/gene="EHT1"
/locus_tag="YBR177C"
/db_xref="GeneID:852476"
mRNA complement(584807..586162)
/gene="EHT1"
/locus_tag="YBR177C"
/product="Eht1p"
/transcript_id="NM_001178525.3"
/db_xref="GI:398365306"
/db_xref="GeneID:852476"
CDS complement(584807..586162)
/gene="EHT1"
/locus_tag="YBR177C"
/EC_number="2.3.1.84"
/EC_number="3.1.1.-"
/note="Acyl-coenzymeA:ethanol O-acyltransferase that plays
a minor role in medium-chain fatty acid ethyl ester
biosynthesis; possesses short-chain esterase activity;
localizes to lipid particles and the mitochondrial outer
membrane"
/codon_start=1
/product="Eht1p"
/protein_id="NP_009736.3"
/db_xref="GI:398365307"
/db_xref="SGD:S000000381"
/db_xref="GeneID:852476"
/translation="MSEVSKWPAINPFHWGYNGTVSHIVGENGSIKLHLKDNKEQVDF
DEFANKYVPTLKNGAQFKLSPYLFTGILQTLYLGAADFSKKFPVFYGREIVKFSDGGV
CTADWLIDSWKKDYEFDQSTTSFDKKKFDKDEKATHPEGWPRLQPRTRYLKDNELEEL
REVDLPLVVILHGLAGGSHEPIIRSLAENLSRSGRFQVVVLNTRGCARSKITTRNLFT
AYHTMDIREFLQREKQRHPDRKLYAVGCSFGATMLANYLGEEGDKSPLSAAATLCNPW
DLLLSAIRMSQDWWSRTLFSKNIAQFLTRTVQVNMGELGVPNGSLPDHPPTVKNPSFY
MFTPENLIKAKSFKSTREFDEVYTAPALGFPNAMEYYKAASSINRVDTIRVPTLVINS
RDDPVVGPDQPYSIVEKNPRILYCRTDLGGHLAYLDKDNNSWATKAIAEFFTKFDELV
V"
gene complement(586547..589114)
/gene="FZO1"
/locus_tag="YBR179C"
/db_xref="GeneID:852477"
mRNA complement(586547..589114)
/gene="FZO1"
/locus_tag="YBR179C"
/product="Fzo1p"
/transcript_id="NM_001178527.1"
/db_xref="GI:296142841"
/db_xref="GeneID:852477"
CDS complement(586547..589114)
/gene="FZO1"
/locus_tag="YBR179C"
/EC_number="3.6.5.-"
/note="Mitofusin; integral membrane protein involved in
mitochondrial outer membrane tethering and fusion; role in
mitochondrial genome maintenance; efficient tethering and
degradation of Fzo1p requires an intact N-terminal GTPase
domain; targeted for destruction by the ubiquitin ligase
SCF-Mdm30p and the cytosolic ubiquitin-proteasome system"
/codon_start=1
/product="Fzo1p"
/protein_id="NP_009738.1"
/db_xref="GI:6319656"
/db_xref="SGD:S000000383"
/db_xref="GeneID:852477"
/translation="MSEGKQQFKDSNKPHKDSTDQDDDAATIVPQTLTYSRNEGHFLG
SNFHGVTDDRTTLFDGEEGRREDDLLPSLRSSNSKAHLISSQLSQWNYNNNRVLLKRS
ILKTQAFMDQLQEENNIRPIFIAANDEREKLHVLQLNIKLDGQYNTKEKNGFNIEKKA
LSKLFHSQIVSVTNHLNALKKRVDDVSSKVFITGDVNTGKSALCNSLLKQRLLPEDQL
PCTNVFSEILEARENDGIEEVHAIPLNIAPTLKEAIDMYSIQNPKTYEIHTLKELPDL
VPQNGKYALLKIYIKDDKRPASTSLLRNGTVDISLIDSPGLNMDSLQTAEVMSRQEEI
DLVIFVVNAENQLTLSAKEFISLASREKKLMFFVVKKFDKIRDKQRCKELILKQIRDL
SPETYKRAADFVHFVSKNGDELPHYHNENDNEDHGDRKPDDDPYSSSDPDPDFDSLED
SLRNFVLKKRSLSKLLPAKTYLSKLLSDIIMISKSNMKMYSEEEIKINEQLETLRPEI
LSARAKCNDLTTSVDQMAEQTITMTYNNTKEALLNALDVPLHEYPKYQGLGQIYDFIF
STEAFIANQIDESIGSSELFAKQKTDLLVKKIYEIGKNELGDDFMCERVFRSELMFRK
RKHLIGKRLKVSLSITDLFAPTWKGFLSYLSWQKPVTAPLPDIEGQTNEGQIGLMKYL
GLKNYPLTQYWSRPSLLFTSKIPTLTLYFLGSTKVVGNIILNGIKLSSWSSLKKLSVP
VIVVGSLLGLTYLIHDLPRALPMNLSIKYKRKLQELDYIHLNAQRTSNEVRDVLRVPT
REILRSCEIIMDKKQITKKELENKKESNLLSIKFFQSLYEGTVAQKLMVEEINLDID"
gene 589741..591459
/gene="DTR1"
/locus_tag="YBR180W"
/db_xref="GeneID:852478"
mRNA 589741..591459
/gene="DTR1"
/locus_tag="YBR180W"
/product="Dtr1p"
/transcript_id="NM_001178528.1"
/db_xref="GI:296142842"
/db_xref="GeneID:852478"
CDS 589741..591459
/gene="DTR1"
/locus_tag="YBR180W"
/note="Putative dityrosine transporter of the major
facilitator superfamily; member of the 12-spanner
drug:H(+) antiporter DHA1 family; required for spore wall
synthesis; expressed during sporulation"
/codon_start=1
/product="Dtr1p"
/protein_id="NP_009739.1"
/db_xref="GI:6319657"
/db_xref="SGD:S000000384"
/db_xref="GeneID:852478"
/translation="MGSEPFQKKNLGLQINSQESGTTRSTFHSLEDLGDDVINESWDQ
VNQKRANIDHDVFHEHPDSSPSLSAQKAKTKEEEVAVKSSNSQSRDPSPDTQAHIPYT
YFSKDQRLIIFGIIIFIGFLGPMSGNIYIPALPLLQREYDVSATTINATVSVFMAVFS
VGPLFWGALADFGGRKFLYMVSLSLMLIVNILLAAVPVNIAALFVLRIFQAFASSSVI
SLGAGTVTDVVPPKHRGKAIAYFMMGPNMGPIIAPIVAGLILMKGNYWRWLFGFTSIM
TGIALILVTALLPETLRCIVGNGDPKWGDKKDERENNESPFFEGNKISHRRLFPDIGI
RKPVNNDAFFQENFPKPPKAGLTLYWKMIKCPPIIITSVSTALLFSSYYAFSVTFSYY
LEHDYRFTMLEIGAAYVCPGVAMLLGSQSGGHLSDYLRSRWIKSHPKKKFPAEFRLLL
NLIGILLTICGTIGYGWAIFFHYHFVVLLVFSALTAFGMTWCSNTSMTYLTELFPKRA
AGTVAVSSFFRNVGAAISSAIILQLCNAMGIGWCFTGLGLCSSISLIGILYLLIFQRK
YTAKEF"
gene complement(591712..592774)
/gene="RPS6B"
/locus_tag="YBR181C"
/gene_synonym="LPG18; RPS101; RPS102"
/db_xref="GeneID:852479"
mRNA complement(join(591712..592416,592769..592774))
/gene="RPS6B"
/locus_tag="YBR181C"
/gene_synonym="LPG18; RPS101; RPS102"
/product="ribosomal 40S subunit protein S6B"
/transcript_id="NM_001178529.3"
/db_xref="GI:398365320"
/db_xref="GeneID:852479"
CDS complement(join(591712..592416,592769..592774))
/gene="RPS6B"
/locus_tag="YBR181C"
/gene_synonym="LPG18; RPS101; RPS102"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S6, no
bacterial homolog; RPS6B has a paralog, RPS6A, that arose
from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S6B"
/protein_id="NP_009740.3"
/db_xref="GI:398365321"
/db_xref="SGD:S000000385"
/db_xref="GeneID:852479"
/translation="MKLNISYPVNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDE
FKGYVFKISGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGAIV
GPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKEDDVRDFVIRR
EVTKGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQAQREAAAEYAQLLAKRLSE
RKAEKAEIRKRRASSLKA"
gene complement(593506..594864)
/gene="SMP1"
/locus_tag="YBR182C"
/db_xref="GeneID:852480"
mRNA complement(593506..594864)
/gene="SMP1"
/locus_tag="YBR182C"
/product="Smp1p"
/transcript_id="NM_001178530.3"
/db_xref="GI:398365330"
/db_xref="GeneID:852480"
CDS complement(593506..594864)
/gene="SMP1"
/locus_tag="YBR182C"
/note="Putative transcription factor of the MADS-box
family; involved in regulating the response to osmotic
stress; SMP1 has a paralog, RLM1, that arose from the
whole genome duplication"
/codon_start=1
/product="Smp1p"
/protein_id="NP_009741.3"
/db_xref="GI:398365331"
/db_xref="SGD:S000000386"
/db_xref="GeneID:852480"
/translation="MGRRKIEIEPIKDDRNRTVTFIKRKAGLFKKAHELSVLCQVDIA
VIILGSNNTFYEYSSVDMSNLLNVHQNNTDLPHNIIEPSDYGDYVKKPRVVLNERKRR
RRRATVLQPASHSGSCTVSSQDSSSVQNNGNLSAPLASNDAGNAGVSTPLVHCHGAIS
RSGSNHSDCARNSADYQMLQGGLNSGGSFHANDYKESVDQQHVANEAIHRNFMNKRIR
PDTHLLLSESNHSNYHNFYPSPYENLPKPSLPASLVGNIPSFQSQFVQVIPANSNPMG
KGFNGTGDSESFEAKQKIHPTVAISNTLEGPAPVQAMVHHLHQLNSNRGKLSGKPYLK
LNIPKATNDACQRSPAMYSGTASPKTDVQATPNQMLASNMSSPLSRSKFLGFKNNDMD
DLYHNGRCGSTYVNNKTFFLKPPIGRPPKFPKSPSSSIVVFPSSVASSTLKSTSSTNS
PD"
gene complement(595361..595555)
/locus_tag="YBR182C-A"
/db_xref="GeneID:1466446"
mRNA complement(595361..595555)
/locus_tag="YBR182C-A"
/product="hypothetical protein"
/transcript_id="NM_001184586.1"
/db_xref="GI:296142845"
/db_xref="GeneID:1466446"
CDS complement(595361..595555)
/locus_tag="YBR182C-A"
/note="hypothetical protein; identified by gene-trapping,
microarray-based expression analysis, and genome-wide
homology searching"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878050.1"
/db_xref="GI:33438768"
/db_xref="SGD:S000028603"
/db_xref="GeneID:1466446"
/translation="MKIFTLYTMIQQYFFDNGGVYSIKNFYSAVPKEKMNIILVSLDC
ELQKLALKLSKKTSGTHTTH"
gene 596115..597065
/gene="YPC1"
/locus_tag="YBR183W"
/db_xref="GeneID:852481"
mRNA 596115..597065
/gene="YPC1"
/locus_tag="YBR183W"
/product="phytoceramidase"
/transcript_id="NM_001178531.1"
/db_xref="GI:296142846"
/db_xref="GeneID:852481"
CDS 596115..597065
/gene="YPC1"
/locus_tag="YBR183W"
/EC_number="3.5.1.-"
/note="Alkaline ceramidase that also has reverse
(CoA-independent) ceramide synthase activity, catalyzes
both breakdown and synthesis of phytoceramide;
overexpression confers fumonisin B1 resistance"
/codon_start=1
/product="phytoceramidase"
/protein_id="NP_009742.1"
/db_xref="GI:6319660"
/db_xref="SGD:S000000387"
/db_xref="GeneID:852481"
/translation="MGIFRWNYPESSVPGVWGETTSTIDWCEENYVVSPYIAEWSNTL
TNSVFILSAIYTTYSAYKNKLEKRFLLIGFGYGLVGVGSWLFHMTLKYRFQLLDELPM
IYAMCIPTWSLVCEAKEALLNGDNHKKVPLFEQIFIGVIIGLAVTTASILYVIYKNVD
IHQILFGVQIVVVAATAGSLTYRYVHDPLAKRNLKASMALGAILFLSGYISWLLDIHY
CSFWVHVRRSILALPLGVLLEPHGWWHILTGMGIYFYIVSLEHLRVITLNVSCNYQFI
WRWKVFPELIWKGRKPSTRYSLELFGPYVEDQSIEVKKEK"
gene 597363..598934
/locus_tag="YBR184W"
/db_xref="GeneID:852482"
mRNA 597363..598934
/locus_tag="YBR184W"
/product="hypothetical protein"
/transcript_id="NM_001178532.3"
/db_xref="GI:398365348"
/db_xref="GeneID:852482"
CDS 597363..598934
/locus_tag="YBR184W"
/note="hypothetical protein; YBR184W is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009743.3"
/db_xref="GI:398365349"
/db_xref="SGD:S000000388"
/db_xref="GeneID:852482"
/translation="MYQNNVLNAILASEKSNFQYDSGTILRNHKRPIITFNNNIEHTV
SEPNNFTGYEEKEDLDIMDICPYYPKARMLADAIQHAKTSASENKMELSMKTIPCLKK
ENVHVEKGHDWSQLSTSRICKILEDIADKKNKTRRQSAPLQKTKYFPTNENQNTDIEN
QNWSQIPNEDICALIEKIASRRNKNRKRKNLSCSKVQEIQGNIDLPKKDVQEGDISDS
SLFAAVRGTKKVSGYDYNSEDKIPNAIRLPYCKQILRLFSLLQMKRNDLIVTSENCNS
GVFFSNFNYQLQVKSNCIANISSTLSFLPHHEITVYTSFILYPNVVDNIWECTRYAIQ
LLKSEAAQFTLLRDIYSGFTIILSNHRYHPKGFSADYCYSANELTLFLFVIRTGQKKV
LYRSIPHNTAAIEKDSSFDTENRKRRSEEEVVLKCRKCSNNSLALKEISTYRLDSAEG
FEKSQPLKDEAKLSDMNYVQGSISYNRTILTGLWKLFHRLCCKDRYRKTNLSETLFYD
DSTERWVRMGELMHY"
gene complement(599123..599959)
/gene="MBA1"
/locus_tag="YBR185C"
/db_xref="GeneID:852483"
mRNA complement(599123..599959)
/gene="MBA1"
/locus_tag="YBR185C"
/product="Mba1p"
/transcript_id="NM_001178533.3"
/db_xref="GI:398365354"
/db_xref="GeneID:852483"
CDS complement(599123..599959)
/gene="MBA1"
/locus_tag="YBR185C"
/note="Membrane-associated mitochondrial ribosome
receptor; forms a complex with Mdm38p that may facilitate
recruitment of mRNA-specific translational activators to
ribosomes; possible role in protein export from the matrix
to inner membrane"
/codon_start=1
/product="Mba1p"
/protein_id="NP_009744.3"
/db_xref="GI:398365355"
/db_xref="SGD:S000000389"
/db_xref="GeneID:852483"
/translation="MSVLRSTCLFFPPRSLLISFNKRRLFSTSRLILNKESETTKKKD
KSKQQDFNPRHLGVAAEIFIPSAYKNLPNVFAHPLIVANALIRRLYTFGLNSVQVALF
RFQSGIKPSFLLWKNKAIETYINVNTSFAHKNLSDIKGLVSLWVQEALEARSRQLPGN
ATLDWQLIKFNAVPKLVSVQPIMIPGMPLEHLQLVYKFDTKQRLIKVNQQTKKTETLD
RDVVDYIAFLCDATTNDMILMGSLFESKPNDKLPKSYEDDAKVAIHRMKVNGDIYRLP
PS"
gene 600553..602360
/gene="PCH2"
/locus_tag="YBR186W"
/db_xref="GeneID:852484"
mRNA join(600553..602103,602217..602360)
/gene="PCH2"
/locus_tag="YBR186W"
/product="Pch2p"
/transcript_id="NM_001178534.1"
/db_xref="GI:296142849"
/db_xref="GeneID:852484"
CDS join(600553..602103,602217..602360)
/gene="PCH2"
/locus_tag="YBR186W"
/note="Nucleolar component of the pachytene checkpoint,
which prevents chromosome segregation when recombination
and chromosome synapsis are defective; also represses
meiotic interhomolog recombination in the rDNA; required
for meiotic double-stranded break formation"
/codon_start=1
/product="Pch2p"
/protein_id="NP_009745.2"
/db_xref="GI:9755327"
/db_xref="SGD:S000000390"
/db_xref="GeneID:852484"
/translation="MSYIVDLQVRGSSLRVIKCMFREDEQISSLHSGSDSKQNSNKKL
GEFLNLLKAVVKRKLESFPKDRLKTSIITGQELMREGQGSIEIKDPPTEAQQHLIRSL
AKVLLHQFSSINGKVNTVNEGQDNLFLSLFVKKISIEQQSTSHVSIKLNFHEKINLGQ
HIDSILDSEETNESDTYHMGSVDEFIIYPFCCLEEQDELKNGSILSTEFDKIDLELDE
DDGFEGETLNNCINSVGNFDIPLSKQTLNLVNISYLPGTTFEGQWESLYFGNNIKERL
YSYATISLKIARFKQTGDSNQEDITTLITNNKLLLVHGPPGTGKTTLCKALCQKLSVR
REFSDGSDTIDTNYKGIIIELSCARIFSKWFGESSKNISIVFKDIEELLKVNEGRGIF
ICLLIDEVEAIASSRTNLSSRNESTDGIRVVNTLLTQLDRLKKYHNFLALATSNLLDS
LDDAFVDRADGVFYVGNPTAEGILHILKVCIEEMITSGIILFHARSTGVKFFNKYQDI
LRKIAIKCSTVDISGRTIRKLPLMCLSEYFRTFPVDDDEFVLALAMSARKLSAARK"
gene 602634..603476
/gene="GDT1"
/locus_tag="YBR187W"
/db_xref="GeneID:852485"
mRNA 602634..603476
/gene="GDT1"
/locus_tag="YBR187W"
/product="Gdt1p"
/transcript_id="NM_001178535.1"
/db_xref="GI:296142850"
/db_xref="GeneID:852485"
CDS 602634..603476
/gene="GDT1"
/locus_tag="YBR187W"
/note="hypothetical protein; expression is reduced in a
gcr1 null mutant; GFP-fusion protein localizes to the
vacuole; expression pattern and physical interactions
suggest a possible role in ribosome biogenesis"
/codon_start=1
/product="Gdt1p"
/protein_id="NP_009746.1"
/db_xref="GI:6319664"
/db_xref="SGD:S000000391"
/db_xref="GeneID:852485"
/translation="MGNMIKKASLIALLPLFTAAAAAATDAETSMESGSSSHLKSFLM
SVSMIGLSEIGDKTFLIAALMAMRHKRVLVFSAAATSLAIMTILSGVVGHSAVAFLSE
RYTAFFAGILFLVFGYKLTMEGLEMSKDAGVEEEMAEVEEEIAIKDMNQDMDDVEKGG
DTAYDKQLKNASIGKKIVHRIRELASFMFSPVWVQIFLMVFLGELGDRSQISIIAMAT
DSDYWYVIAGAVIGHAICSGLAVVGGKLLATRISIRTITLASSLLFFIFALMYIYQAF
TTQD"
gene complement(603685..604107)
/gene="NTC20"
/locus_tag="YBR188C"
/db_xref="GeneID:852486"
mRNA complement(603685..604107)
/gene="NTC20"
/locus_tag="YBR188C"
/product="Ntc20p"
/transcript_id="NM_001178536.3"
/db_xref="GI:398365370"
/db_xref="GeneID:852486"
CDS complement(603685..604107)
/gene="NTC20"
/locus_tag="YBR188C"
/note="Member of the NineTeen Complex (NTC) that contains
Prp19p and stabilizes U6 snRNA in catalytic forms of the
spliceosome containing U2, U5, and U6 snRNAs"
/codon_start=1
/product="Ntc20p"
/protein_id="NP_009747.3"
/db_xref="GI:398365371"
/db_xref="SGD:S000000392"
/db_xref="GeneID:852486"
/translation="MPSLRDLSLERDQELNQLRARINQLGKTGKEEANDFVGLNISNE
PVYDTVIQTGQSSNATNSFVQETIQKTKQKESGQPYIIPQKNEHQRYIDKVCETSDLK
AKLAPIMEVLEKKTNEKIKGIIRKRVLQEPDRDNDDSG"
gene 604508..605508
/gene="RPS9B"
/locus_tag="YBR189W"
/gene_synonym="RPS13A; SUP46"
/db_xref="GeneID:852487"
mRNA join(604508..604514,604928..605508)
/gene="RPS9B"
/locus_tag="YBR189W"
/gene_synonym="RPS13A; SUP46"
/product="ribosomal 40S subunit protein S9B"
/transcript_id="NM_001178537.3"
/db_xref="GI:398365376"
/db_xref="GeneID:852487"
CDS join(604508..604514,604928..605508)
/gene="RPS9B"
/locus_tag="YBR189W"
/gene_synonym="RPS13A; SUP46"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S9 and
bacterial S4; RPS9B has a paralog, RPS9A, that arose from
the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S9B"
/protein_id="NP_009748.3"
/db_xref="GI:398365377"
/db_xref="SGD:S000000393"
/db_xref="GeneID:852487"
/translation="MPRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKREIYR
ISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVE
DFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAP
TSPFGGARPGRVARRNAARKAEASGEAAEEAEDEE"
gene 606270..607140
/gene="RPL21A"
/locus_tag="YBR191W"
/gene_synonym="URP1"
/db_xref="GeneID:852489"
mRNA join(606270..606280,606669..607140)
/gene="RPL21A"
/locus_tag="YBR191W"
/gene_synonym="URP1"
/product="ribosomal 60S subunit protein L21A"
/transcript_id="NM_001178539.1"
/db_xref="GI:296142853"
/db_xref="GeneID:852489"
CDS join(606270..606280,606669..607140)
/gene="RPL21A"
/locus_tag="YBR191W"
/gene_synonym="URP1"
/note="Ribosomal 60S subunit protein L21A; homologous to
mammalian ribosomal protein L21, no bacterial homolog;
RPL21A has a paralog, RPL21B, that arose from the whole
genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L21A"
/protein_id="NP_009750.1"
/db_xref="GI:6319668"
/db_xref="SGD:S000000395"
/db_xref="GeneID:852489"
/translation="MGKSHGYRSRTRYMFQRDFRKHGAVHLSTYLKVYKVGDIVDIKA
NGSIQKGMPHKFYQGKTGVVYNVTKSSVGVIINKMVGNRYLEKRLNLRVEHIKHSKCR
QEFLERVKANAAKRAEAKAQGVAVQLKRQPAQPRESRIVSTEGNVPQTLAPVPYETFI
"
gene 607652..608785
/gene="RIM2"
/locus_tag="YBR192W"
/gene_synonym="PYT1"
/db_xref="GeneID:852491"
mRNA 607652..608785
/gene="RIM2"
/locus_tag="YBR192W"
/gene_synonym="PYT1"
/product="Rim2p"
/transcript_id="NM_001178540.1"
/db_xref="GI:296142854"
/db_xref="GeneID:852491"
CDS 607652..608785
/gene="RIM2"
/locus_tag="YBR192W"
/gene_synonym="PYT1"
/note="Mitochondrial pyrimidine nucleotide transporter;
imports pyrimidine nucleoside triphosphates and exports
pyrimidine nucleoside monophosphates; member of the
mitochondrial carrier family"
/codon_start=1
/product="Rim2p"
/protein_id="NP_009751.1"
/db_xref="GI:6319669"
/db_xref="SGD:S000000396"
/db_xref="GeneID:852491"
/translation="MPKKSIEEWEEDAIESVPYLASDEKGSNYKEATQIPLNLKQSEI
ENHPTVKPWVHFVAGGIGGMAGAVVTCPFDLVKTRLQSDIFLKAYKSQAVNISKGSTR
PKSINYVIQAGTHFKETLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSINFFTYGTT
KDMYAKAFNNGQETPMIHLMAAATAGWATATATNPIWLIKTRVQLDKAGKTSVRQYKN
SWDCLKSVIRNEGFTGLYKGLSASYLGSVEGILQWLLYEQMKRLIKERSIEKFGYQAE
GTKSTSEKVKEWCQRSGSAGLAKFVASIATYPHEVVRTRLRQTPKENGKRKYTGLVQS
FKVIIKEEGLFSMYSGLTPHLMRTVPNSIIMFGTWEIVIRLLS"
gene complement(609082..609753)
/gene="MED8"
/locus_tag="YBR193C"
/db_xref="GeneID:852492"
mRNA complement(609082..609753)
/gene="MED8"
/locus_tag="YBR193C"
/product="Med8p"
/transcript_id="NM_001178541.3"
/db_xref="GI:398365394"
/db_xref="GeneID:852492"
CDS complement(609082..609753)
/gene="MED8"
/locus_tag="YBR193C"
/note="Subunit of the RNA polymerase II mediator complex;
associates with core polymerase subunits to form the RNA
polymerase II holoenzyme; essential for transcriptional
regulation"
/codon_start=1
/product="Med8p"
/protein_id="NP_009752.3"
/db_xref="GI:398365395"
/db_xref="SGD:S000000397"
/db_xref="GeneID:852492"
/translation="MSQSTASLVPEGNQGSLQEDVSFDFNGVPGQALDAVRMRLAQLT
HSLRRIRDEMSKAELPQWYTLQSQLNVTLSQLVSVTSTLQHFQETLDSTVVYPLPKFP
TTSHESLVTTLLRKKNIPEVDEWMKYVRETSGVTTALLKDEEIEKLLQQDREITNWAR
TTFRNEYGKHDFKNEESLSEEHASLLVRDSKPSKPFNVDDVLKFTFTGEKPIITGSTS
TSSSN"
gene 610038..610409
/gene="AIM4"
/locus_tag="YBR194W"
/gene_synonym="SOY1"
/db_xref="GeneID:852493"
mRNA 610038..610409
/gene="AIM4"
/locus_tag="YBR194W"
/gene_synonym="SOY1"
/product="Aim4p"
/transcript_id="NM_001178542.3"
/db_xref="GI:398365398"
/db_xref="GeneID:852493"
CDS 610038..610409
/gene="AIM4"
/locus_tag="YBR194W"
/gene_synonym="SOY1"
/note="Protein proposed to be associated with the nuclear
pore complex; null mutant is viable, displays elevated
frequency of mitochondrial genome loss and is sensitive to
freeze-thaw stress"
/codon_start=1
/product="Aim4p"
/protein_id="NP_009753.3"
/db_xref="GI:398365399"
/db_xref="SGD:S000000398"
/db_xref="GeneID:852493"
/translation="MDQKKDPSNNLTERRVSKVQRPNKKKVRNQVESLSRNLERNKEG
QLLQTVSKGHLEADSGHSLGREKENGELGIRSIFYDKDWNPRGTAPSHYRNIPYNPAT
FKRRTEVQARLGNLENIKIPK"
gene complement(610614..611882)
/gene="MSI1"
/locus_tag="YBR195C"
/gene_synonym="CAC3"
/db_xref="GeneID:852494"
mRNA complement(610614..611882)
/gene="MSI1"
/locus_tag="YBR195C"
/gene_synonym="CAC3"
/product="Msi1p"
/transcript_id="NM_001178543.1"
/db_xref="GI:296142857"
/db_xref="GeneID:852494"
CDS complement(610614..611882)
/gene="MSI1"
/locus_tag="YBR195C"
/gene_synonym="CAC3"
/note="Subunit of chromatin assembly factor I (CAF-1);
chromatin assembly by CAF-1 is important for multiple
processes including silencing at telomeres, mating type
loci, and rDNA; maintenance of kinetochore structure;
deactivation of the DNA damage checkpoint after DNA
repair; and chromatin dynamics during transcription; Msi1p
localizes to both nucleus and cytoplasm and has an
independent role as a negative regulator of the RAS/cAMP
pathway via sequestration of Npr1p kinase"
/codon_start=1
/product="Msi1p"
/protein_id="NP_009754.1"
/db_xref="GI:6319672"
/db_xref="SGD:S000000399"
/db_xref="GeneID:852494"
/translation="MNQCAKDITHEASSIPIDLQERYSHWKKNTKLLYDYLNTNSTKW
PSLTCQFFPDLDTTSDEHRILLSSFTSSQKPEDETIYISKISTLGHIKWSSLNNFDMD
EMEFKPENSTRFPSKHLVNDISIFFPNGECNRARYLPQNPDIIAGASSDGAIYIFDRT
KHGSTRIRQSKISHPFETKLFGSHGVIQDVEAMDTSSADINEATSLAWNLQQEALLLS
SHSNGQVQVWDIKQYSHENPIIDLPLVSINSDGTAVNDVTWMPTHDSLFAACTEGNAV
SLLDLRTKKEKLQSNREKHDGGVNSCRFNYKNSLILASADSNGRLNLWDIRNMNKSPI
ATMEHGTSVSTLEWSPNFDTVLATAGQEDGLVKLWDTSCEETIFTHGGHMLGVNDISW
DAHDPWLMCSVANDNSVHIWKPAGNLVGHS"
gene complement(612236..613900)
/gene="PGI1"
/locus_tag="YBR196C"
/gene_synonym="CDC30"
/db_xref="GeneID:852495"
mRNA complement(612236..613900)
/gene="PGI1"
/locus_tag="YBR196C"
/gene_synonym="CDC30"
/product="glucose-6-phosphate isomerase"
/transcript_id="NM_001178544.1"
/db_xref="GI:296142858"
/db_xref="GeneID:852495"
CDS complement(612236..613900)
/gene="PGI1"
/locus_tag="YBR196C"
/gene_synonym="CDC30"
/EC_number="5.3.1.9"
/note="Glycolytic enzyme phosphoglucose isomerase,
catalyzes the interconversion of glucose-6-phosphate and
fructose-6-phosphate; required for cell cycle progression
and completion of the gluconeogenic events of sporulation"
/codon_start=1
/product="glucose-6-phosphate isomerase"
/protein_id="NP_009755.1"
/db_xref="GI:6319673"
/db_xref="SGD:S000000400"
/db_xref="GeneID:852495"
/translation="MSNNSFTNFKLATELPAWSKLQKIYESQGKTLSVKQEFQKDAKR
FEKLNKTFTNYDGSKILFDYSKNLVNDEIIAALIELAKEANVTGLRDAMFKGEHINST
EDRAVYHVALRNRANKPMYVDGVNVAPEVDSVLKHMKEFSEQVRSGEWKGYTGKKITD
VVNIGIGGSDLGPVMVTEALKHYAGVLDVHFVSNIDGTHIAETLKVVDPETTLFLIAS
KTFTTAETITNANTAKNWFLSKTGNDPSHIAKHFAALSTNETEVAKFGIDTKNMFGFE
SWVGGRYSVWSAIGLSVALYIGYDNFEAFLKGAEAVDNHFTQTPLEDNIPLLGGLLSV
WYNNFFGAQTHLVAPFDQYLHRFPAYLQQLSMESNGKSVTRGNVFTDYSTGSILFGEP
ATNAQHSFFQLVHQGTKLIPSDFILAAQSHNPIENKLHQKMLASNFFAQAEALMVGKD
EEQVKAEGATGGLVPHKVFSGNRPTTSILAQKITPATLGALIAYYEHVTFTEGAIWNI
NSFDQWGVELGKVLAKVIGKELDNSSTISTHDASTNGLINQFKEWM"
gene complement(614024..614173)
/locus_tag="YBR196C-A"
/db_xref="GeneID:1466447"
mRNA complement(614024..614173)
/locus_tag="YBR196C-A"
/product="hypothetical protein"
/transcript_id="NM_001184541.3"
/db_xref="GI:398365410"
/db_xref="GeneID:1466447"
CDS complement(614024..614173)
/locus_tag="YBR196C-A"
/note="hypothetical protein; identified by fungal homology
and RT-PCR"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878051.3"
/db_xref="GI:398365411"
/db_xref="SGD:S000028534"
/db_xref="GeneID:1466447"
/translation="MSRVYIYPLTVFYFFAIEMSVFCYYNWFYRRNFPYLFRPIFPFL
IVLIS"
gene complement(614526..614630)
/locus_tag="YBR196C-B"
/db_xref="GeneID:1466448"
mRNA complement(614526..614630)
/locus_tag="YBR196C-B"
/product="hypothetical protein"
/transcript_id="NM_001184643.3"
/db_xref="GI:398365422"
/db_xref="GeneID:1466448"
CDS complement(614526..614630)
/locus_tag="YBR196C-B"
/note="hypothetical protein; identified by expression
profiling and mass spectrometry"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878052.3"
/db_xref="GI:398365423"
/db_xref="SGD:S000028816"
/db_xref="GeneID:1466448"
/translation="MWVVLSKEKILLKKAYYAKTILFSALVLRGVRGE"
gene complement(615203..615856)
/locus_tag="YBR197C"
/db_xref="GeneID:852496"
mRNA complement(615203..615856)
/locus_tag="YBR197C"
/product="hypothetical protein"
/transcript_id="NM_001178545.1"
/db_xref="GI:296142861"
/db_xref="GeneID:852496"
CDS complement(615203..615856)
/locus_tag="YBR197C"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and
nucleus; YBR197C is not an essential gene; relative
distribution to the nucleus increases upon DNA replication
stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009756.1"
/db_xref="GI:6319674"
/db_xref="SGD:S000000401"
/db_xref="GeneID:852496"
/translation="MGVKQTPPVQVKVSDADSTNRRKSSSQEGNPQLVQLKAKSDKDK
RKGSSDSTASIMGSSNALPTKNLTTPPALNPLTTSISRGNTAYERSVNGSRITMHSNL
APTETQDVSWSEIDTLDDVKKMAKEPIVNDGFPRDFESNLTQMRKSHAQLLRLMRERN
QRLKYAKLRSPPHKDQHNSATNKDQEPDEVLHDPEIALDGEKYVSQVVDTIKDVHRC"
gene complement(616127..618523)
/gene="TAF5"
/locus_tag="YBR198C"
/gene_synonym="TAF90"
/db_xref="GeneID:852497"
mRNA complement(616127..618523)
/gene="TAF5"
/locus_tag="YBR198C"
/gene_synonym="TAF90"
/product="Taf5p"
/transcript_id="NM_001178546.1"
/db_xref="GI:296142862"
/db_xref="GeneID:852497"
CDS complement(616127..618523)
/gene="TAF5"
/locus_tag="YBR198C"
/gene_synonym="TAF90"
/note="Subunit (90 kDa) of TFIID and SAGA complexes,
involved in RNA polymerase II transcription initiation and
in chromatin modification"
/codon_start=1
/product="Taf5p"
/protein_id="NP_009757.1"
/db_xref="GI:6319675"
/db_xref="SGD:S000000402"
/db_xref="GeneID:852497"
/translation="MSQKQSTNQNQNGTHQPQPVKNQRTNNAAGANSGQQPQQQSQGQ
SQQQGRSNGPFSASDLNRIVLEYLNKKGYHRTEAMLRAESGRTLTPQNKQSPANTKTG
KFPEQSSIPPNPGKTAKPISNPTNLSSKRDAEGGIVSSGRLEGLNAPENYIRAYSMLK
NWVDSSLEIYKPELSYIMYPIFIYLFLNLVAKNPVYARRFFDRFSPDFKDFHGSEINR
LFSVNSIDHIKENEVASAFQSHKYRITMSKTTLNLLLYFLNENESIGGSLIISVINQH
LDPNIVESVTAREKLADGIKVLSDSENGNGKQNLEMNSVPVKLGPFPKDEEFVKEIET
ELKIKDDQEKQLNQQTAGDNYSGANNRTLLQEYKAMNNEKFKDNTGDDDKDKIKDKIA
KDEEKKESELKVDGEKKDSNLSSPARDILPLPPKTALDLKLEIQKVKESRDAIKLDNL
QLALPSVCMYTFQNTNKDMSCLDFSDDCRIAAAGFQDSYIKIWSLDGSSLNNPNIALN
NNDKDEDPTCKTLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGH
NHPVWDVSFSPLGHYFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYV
FTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGT
GKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWDLKKATTEPSAEPDEPFIG
YLGDVTASINQDIKEYGRRRTVIPTSDLVASFYTKKTPVFKVKFSRSNLALAGGAFRP
"
gene 618909..620303
/gene="KTR4"
/locus_tag="YBR199W"
/db_xref="GeneID:852498"
mRNA 618909..620303
/gene="KTR4"
/locus_tag="YBR199W"
/product="Ktr4p"
/transcript_id="NM_001178547.3"
/db_xref="GI:398365436"
/db_xref="GeneID:852498"
CDS 618909..620303
/gene="KTR4"
/locus_tag="YBR199W"
/EC_number="2.4.1.131"
/note="Putative mannosyltransferase involved in protein
glycosylation; member of the KRE2/MNT1 mannosyltransferase
family"
/codon_start=1
/product="Ktr4p"
/protein_id="NP_009758.3"
/db_xref="GI:398365437"
/db_xref="SGD:S000000403"
/db_xref="GeneID:852498"
/translation="MRFLSKRILKPVLSVIILISIAVTVVLYFLTANENYLQAVKDSA
KSQYASLRESYKSITGKTESADELPDHDAEVLDSIMDRLHEPLYEKDTFDPNEVLAEN
KQLYEEFLLQEISEPKVDNLVRSGDPLAGKAKGTILSLVRNSDLEDIISSIQQLEEEY
NKNFGYPYTFLNDEEFTDEFKDGIKSILPKDRVVEFGTIGPDNWNMPDSIDRERYDQE
MDKMSKENIQYAEVESYHNMCRFYSKEFYHHPLLSKYKYVWRLEPNVNFYCKINYDVF
QFMNKNDKIYGFVLNLYDSPQTIETLWTSTMDFVEEHPNYLNVNGAFAWLKDNSQNPK
NYDYTQGYSTCHFWTNFEIVDLDFLRSEPYEKYMQYLEEKGGFYYERWGDAPVRSLAL
ALFADKSSIHWFRDIGYHHTPYTNCPTCPADSDRCNGNCVPGKFTPWSDLDNQNCQAT
WIRHSMSEEELEMY"
gene 620872..622527
/gene="BEM1"
/locus_tag="YBR200W"
/gene_synonym="SRO1"
/db_xref="GeneID:852499"
mRNA 620872..622527
/gene="BEM1"
/locus_tag="YBR200W"
/gene_synonym="SRO1"
/product="Bem1p"
/transcript_id="NM_001178548.3"
/db_xref="GI:398365444"
/db_xref="GeneID:852499"
CDS 620872..622527
/gene="BEM1"
/locus_tag="YBR200W"
/gene_synonym="SRO1"
/note="Protein containing SH3-domains, involved in
establishing cell polarity and morphogenesis; functions as
a scaffold protein for complexes that include Cdc24p,
Ste5p, Ste20p, and Rsr1p"
/codon_start=1
/product="Bem1p"
/protein_id="NP_009759.3"
/db_xref="GI:398365445"
/db_xref="SGD:S000000404"
/db_xref="GeneID:852499"
/translation="MLKNFKLSKRDSNGSKGRITSADISTPSHDNGSVIKHIKTVPVR
YLSSSSTPVKSQRDSSPKNRHNSKDITSPEKVIKAKYSYQAQTSKELSFMEGEFFYVS
GDEKDWYKASNPSTGKEGVVPKTYFEVFDRTKPSSVNGSNSSSRKVTNDSLNMGSLYA
IVLYDFKAEKADELTTYVGENLFICAHHNCEWFIAKPIGRLGGPGLVPVGFVSIIDIA
TGYATGNDVIEDIKSVNLPTVQEWKSNIARYKASNISLGSVEQQQQQSITKPQNKSAK
LVDGELLVKASVESFGLEDEKYWFLVCCELSNGKTRQLKRYYQDFYDLQVQLLDAFPA
EAGKLRDAGGQWSKRIMPYIPGPVPYVTNSITKKRKEDLNIYVADLVNLPDYISRSEM
VHSLFVVLNNGFDREFERDENQNNIKTLQENDTATFATASQTSNFASTNQDNTLTGED
LKLNKKLSDLSLSGSKQAPAQSTSGLKTTKIKFYYKDDIFALMLKGDTTYKELRSKIA
PRIDTDNFKLQTKLFDGSGEEIKTDSQVSNIIQAKLKISVHDI"
rep_origin 622671..622939
/note="ARS220;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118351"
gene 622983..623147
/locus_tag="YBR200W-A"
/db_xref="GeneID:1466449"
mRNA 622983..623147
/locus_tag="YBR200W-A"
/product="hypothetical protein"
/transcript_id="NM_001184542.1"
/db_xref="GI:296142865"
/db_xref="GeneID:1466449"
CDS 622983..623147
/locus_tag="YBR200W-A"
/note="hypothetical protein; identified by fungal homology
and RT-PCR"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878053.1"
/db_xref="GI:33438771"
/db_xref="SGD:S000028535"
/db_xref="GeneID:1466449"
/translation="MLLCFHMCQRIMWLPFDLMKWRRFHCGAVLVGTLSLRNRSPKIL
SLYFISDRTG"
gene 623576..624211
/gene="DER1"
/locus_tag="YBR201W"
/db_xref="GeneID:852500"
mRNA 623576..624211
/gene="DER1"
/locus_tag="YBR201W"
/product="Der1p"
/transcript_id="NM_001178549.1"
/db_xref="GI:296142866"
/db_xref="GeneID:852500"
CDS 623576..624211
/gene="DER1"
/locus_tag="YBR201W"
/note="Endoplasmic reticulum membrane protein, required
for ER-associated protein degradation of misfolded or
unassembled proteins; N- and C- termini protrude into the
cytoplasm, has similarity to Dfm1p"
/codon_start=1
/product="Der1p"
/protein_id="NP_009760.1"
/db_xref="GI:6319678"
/db_xref="SGD:S000000405"
/db_xref="GeneID:852500"
/translation="MDAVILNLLGDIPLVTRLWTIGCLVLSGLTSLRIVDPGKVVYSY
DLVFKKGQYGRLLYSIFDYGAFNWISMINIFVSANHLSTLENSFNLRRKFCWIIFLLL
VILVKMTSIEQPAASLGVLLHENLVYYELKKNGNQMNVRFFGAIDVSPSIFPIYMNAV
MYFVYKRSWLEIAMNFMPGHVIYYMDDIIGKIYGIDLCKSPYDWFRNTETP"
gene complement(624493..624696)
/locus_tag="YBR201C-A"
/db_xref="GeneID:3799967"
mRNA complement(624493..624696)
/locus_tag="YBR201C-A"
/product="hypothetical protein"
/transcript_id="NM_001184676.3"
/db_xref="GI:398365462"
/db_xref="GeneID:3799967"
CDS complement(624493..624696)
/locus_tag="YBR201C-A"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001032571.3"
/db_xref="GI:398365463"
/db_xref="SGD:S000087085"
/db_xref="GeneID:3799967"
/translation="MLAMKSFSQVSKSYKASAPSKKLTTLFYVAYITLGLTTPFLLPA
RMASKDTHYYKDEFCSQRSYTRF"
gene 625772..628309
/gene="MCM7"
/locus_tag="YBR202W"
/gene_synonym="CDC47"
/db_xref="GeneID:852501"
mRNA 625772..628309
/gene="MCM7"
/locus_tag="YBR202W"
/gene_synonym="CDC47"
/product="Mcm7p"
/transcript_id="NM_001178550.4"
/db_xref="GI:398365470"
/db_xref="GeneID:852501"
CDS 625772..628309
/gene="MCM7"
/locus_tag="YBR202W"
/gene_synonym="CDC47"
/note="Component of the heterohexameric MCM2-7 complex,
which primes origins of DNA replication in G1 and becomes
an active ATP-dependent helicase that promotes DNA melting
and elongation in S-phase; forms an Mcm4p-6p-7p
subcomplex"
/codon_start=1
/product="Mcm7p"
/protein_id="NP_009761.4"
/db_xref="GI:398365471"
/db_xref="SGD:S000000406"
/db_xref="GeneID:852501"
/translation="MSAALPSIQLPVDYNNLFNEITDFLVTFKQDTLSSDATRNENED
ENLDAENIEQHLLEKGPKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDL
VSAIQQNANHFTELFCRAIDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNE
IRSENLMDTTMDPPSSMNDALREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKK
AISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSR
TFTPLSECTSEECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIH
VNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAGLLTETYLEAQFVRQHKKKFASFS
LTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKI
RGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMIL
EGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAA
ANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNK
QPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFG
QATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESP
TTKIFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLSNCIQEYSYLNVWHLINEG
NTLKFVDDGTMDTDQEDSLVSTPKLAPQTTASANVSAQDSDIDLQDA"
gene 629168..631942
/gene="COS111"
/locus_tag="YBR203W"
/db_xref="GeneID:852502"
mRNA 629168..631942
/gene="COS111"
/locus_tag="YBR203W"
/product="Cos111p"
/transcript_id="NM_001178551.2"
/db_xref="GI:330443460"
/db_xref="GeneID:852502"
CDS 629168..631942
/gene="COS111"
/locus_tag="YBR203W"
/note="Protein required for resistance to the antifungal
drug ciclopirox olamine; not related to the
subtelomerically-encoded COS family; the authentic,
non-tagged protein is detected in highly purified
mitochondria in high-throughput studies"
/codon_start=1
/product="Cos111p"
/protein_id="NP_009762.2"
/db_xref="GI:330443461"
/db_xref="SGD:S000000407"
/db_xref="GeneID:852502"
/translation="MSSASRLQNVNIVSNNYSRYGTSVYDKLYHSNGSGSNNAGKNST
TVGKLSSISQKSRSKQRHGSNCSRSMSQSPLSTFKSPLSNQNQSSAPDDLASIGQRRS
DDVTSLDNETIITMNSRKSRIKKKYKSLISTSSKKFMNKLYDHGASSDSFSIFSLKTS
HSGKHENSRFEKLRKRKYHAWGKFADINDLPVEIIAKILSEFELGRDQKTLVRCLYVS
KKFYKATKIVLYRLPYFTSTYRVAQFVTSLRLHPDNGAYVKVLDLSHLKPGIIGQDSK
DSQGLDDDGHSRRHRRRRRRSTNTSLNLPPATPTSTISNEDDANSGLIKDDASNGSEV
EDLALAGWRDWRYRNEPLYSSPLLNSFKLKKVVSRSSSITSTSSGNSTGVHSTRRQRS
NSSVASITTSIMSSIYNTSHVSLSSTTSNTSNGNISSGSNLSRVSTAGSLKKASAKST
RSSPQKAKPISDITSSSWFRMRLSSRNRKARTANTINLKNSKDKSDDDFKVLKHDSGH
PSNYRSSTLKFSIEQPFSTHHPYANKFLLKYAPYKDLPLGYILHMLNLCPNLVELNLS
NLVICTDFKLINQRSERRRMTSSLLPAVQESSVSAGPEKDLEIVYMTDSGKGYEYYEG
LSKKHSRSSSLGTNPSSWIGGQANWTDYPPPIDAQTKTREEHRRNNTLNNKNVVLKKL
NPFEIFEMICNRNEEKGGYCSLTKVKMNDIVWCRQYMVKYFVMRTFRQHLDYKSMENN
SYERHLFSFRDSGLDRNFSWACNAKLHEFVALMVMDHLSNLDDLGLEELFNIKSEKLY
IKNYCCRDPDILEISNLFDIRYGAGSEADATSDSNLEAESLQFRLTILKTEKPTSFWL
TKVSKDYVSLVVKLCVDDDIDMDKMKVGKPTLRIDSITHNLISRLKELRRVDLRRNVG
ENNYYAESII"
rep_origin 631939..632251
/note="ARS221;
Autonomously Replicating Sequence"
/db_xref="SGD:S000130153"
gene complement(632254..633381)
/gene="LDH1"
/locus_tag="YBR204C"
/db_xref="GeneID:852503"
mRNA complement(632254..633381)
/gene="LDH1"
/locus_tag="YBR204C"
/product="Ldh1p"
/transcript_id="NM_001178552.2"
/db_xref="GI:330443462"
/db_xref="GeneID:852503"
CDS complement(632254..633381)
/gene="LDH1"
/locus_tag="YBR204C"
/EC_number="3.1.1.-"
/note="Serine hydrolase; exhibits active esterase plus
weak triacylglycerol lipase activities; proposed role in
lipid homeostasis, regulating phospholipid and non-polar
lipid levels and required for mobilization of LD-stored
lipids; localizes to the lipid droplet (LD) surface;
contains a classical serine containing catalytic triad
(GxSxG motif)"
/codon_start=1
/product="Ldh1p"
/protein_id="NP_009763.2"
/db_xref="GI:330443463"
/db_xref="SGD:S000000408"
/db_xref="GeneID:852503"
/translation="MNMAERAEATKSWSCEPLSGKTLEEIVQNAENAADLVAYIRKPE
VDLDFRLKFIAEHEEFFNVQLSDRNSRIRTCHNLSDKGIRGDTVFVFVPGLAGNLEQF
EPLLELVDSDQKAFLTLDLPGFGHSSEWSDYPMLKVVELIFVLVCDVLRKWSTAVPNN
DNVNPFNGHKIVLVGHSMGCFLACHLYEQHMADTKAVQTLVLLTPPKAHIEQLSKDKH
IIQWALYGVFKLPWLFDVYRNKFDQVKGLQSSGIKQYFYQQGDDVKLKYRKFWQFKNN
ISNKSRTIIGYLLGWETVDWVKFNGVLTQTDMKQKIIIFGAEKDPIAPIENLEFYKQT
INKECLRKVIILPDCSHNLCFDRPELVCENFQREVIDNSKL"
gene 633622..634836
/gene="KTR3"
/locus_tag="YBR205W"
/db_xref="GeneID:852504"
mRNA 633622..634836
/gene="KTR3"
/locus_tag="YBR205W"
/product="Ktr3p"
/transcript_id="NM_001178553.3"
/db_xref="GI:398365496"
/db_xref="GeneID:852504"
CDS 633622..634836
/gene="KTR3"
/locus_tag="YBR205W"
/EC_number="2.4.1.131"
/note="Putative alpha-1,2-mannosyltransferase; involved in
O- and N-linked protein glycosylation; member of the
KRE2/MNT1 mannosyltransferase family; Svp26p mediates
uptake of Ktr3p into COPII vesicles; relocalizes from
nucleus to vacuole upon DNA replication stress"
/codon_start=1
/product="Ktr3p"
/protein_id="NP_009764.3"
/db_xref="GI:398365497"
/db_xref="SGD:S000000409"
/db_xref="GeneID:852504"
/translation="MSVHHKKKLMPKSALLIRKYQKGIRSSFIGLIIVLSFLFFMSGS
RSPEVPIAQGTSVSRVASKDYLMPFTDKSQGVIHPVDDGKKEKGVMVTLARNSDLWNL
VKSIRHVEDRFNNRYHYDWVFLNDQPFSDEFKRVTSALVSGKAKYGTIPKDHWSIPSW
IDTEKFDEKRLAMGKLDIPYGSSVPYRHMCRFQSGFIWRHPLLEEYEWFWRVDTDITL
FCDIQYDIFKFLKVNNKKYGFILSVSEYERTIPTLWETTKKFIKKNPKFLHKNNLMKF
ISNDDGDTYNMCHFWTNFEIGSLDFFRSDAYREYFDYLDSSGGFFYERWGDAPVHSIA
ASLFLDKSEIHFFDGLGFHHPDFTSCPIEQKIRLQNKCICEPSKDVTWTPDYFCTRKY
FSAGNYKLPPGI"
gene 635146..636543
/gene="FTH1"
/locus_tag="YBR207W"
/db_xref="GeneID:852506"
mRNA 635146..636543
/gene="FTH1"
/locus_tag="YBR207W"
/product="Fth1p"
/transcript_id="NM_001178555.4"
/db_xref="GI:398365500"
/db_xref="GeneID:852506"
CDS 635146..636543
/gene="FTH1"
/locus_tag="YBR207W"
/note="Putative high affinity iron transporter; involved
in transport of intravacuolar stores of iron; forms
complex with Fet5p; expression is regulated by iron;
proposed to play indirect role in endocytosis; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="Fth1p"
/protein_id="NP_009766.4"
/db_xref="GI:398365501"
/db_xref="SGD:S000000411"
/db_xref="GeneID:852506"
/translation="MAFEDYFSFQIFFIFLRESLEIVVIVSILLTIVKQGLSVEDDSP
FEGSSSSAGLPSPNTNTNADSTTAFLQAGPSDGNAIGTSATAANNKSRPLNVEEEEEI
YEYSNELRDQDRESDEHTADNVKLYQKLKIQILAGGAFGLLLCMLIGGAFVSIFYHIG
TDLWTLSEHYYEGVLSLVASVIISVMGLFFLRMGKLREKFRVKLASIIYSKDNNLLGN
KTQKGVKFSEKYSFFILPFITTLREGLEAVVFIGGIGIDQPLSSIPLSMVLATAISTV
FGIFFFRYSSSLSLKICLVVATCFLYLIAAGLFSKGVWQLELQDYVNKCNGQDMSEVG
NGPGSYDISRSVWHVNCCNGEKDGGWMIFTAIFGWTNSATVGSVISYNAYWLVLICAL
KLLMIEEKYGYIPYLPISWQKKRIMKRLSIAKASLDLKHHTSELNSSTSEPDSQRRSK
DSSVPLIIDSSGSAN"
gene complement(636703..642210)
/gene="DUR1,2"
/locus_tag="YBR208C"
/gene_synonym="DUR80"
/db_xref="GeneID:852507"
mRNA complement(636703..642210)
/gene="DUR1,2"
/locus_tag="YBR208C"
/gene_synonym="DUR80"
/product="bifunctional urea carboxylase/allophanate
hydrolase"
/transcript_id="NM_001178556.1"
/db_xref="GI:296142873"
/db_xref="GeneID:852507"
CDS complement(636703..642210)
/gene="DUR1,2"
/locus_tag="YBR208C"
/gene_synonym="DUR80"
/EC_number="6.3.4.6"
/EC_number="3.5.1.54"
/note="Urea amidolyase; contains both urea carboxylase and
allophanate hydrolase activities, degrades urea to CO2 and
NH3; expression sensitive to nitrogen catabolite
repression and induced by allophanate, an intermediate in
allantoin degradation; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="bifunctional urea carboxylase/allophanate
hydrolase"
/protein_id="NP_009767.1"
/db_xref="GI:6319685"
/db_xref="SGD:S000000412"
/db_xref="GeneID:852507"
/translation="MTVSSDTTAEISLGWSIQDWIDFHKSSSSQASLRLLESLLDSQN
VAPVDNAWISLISKENLLHQFQILKSRENKETLPLYGVPIAVKDNIDVRGLPTTAACP
SFAYEPSKDSKVVELLRNAGAIIVGKTNLDQFATGLVGTRSPYGKTPCAFSKEHVSGG
SSAGSASVVARGIVPIALGTDTAGSGRVPAALNNLIGLKPTKGVFSCQGVVPACKSLD
CVSIFALNLSDAERCFRIMCQPDPDNDEYSRPYVSNPLKKFSSNVTIAIPKNIPWYGE
TKNPVLFSNAVENLSRTGANVIEIDFEPLLELARCLYEGTWVAERYQAIQSFLDSKPP
KESLDPTVISIIEGAKKYSAVDCFSFEYKRQGILQKVRRLLESVDVLCVPTCPLNPTM
QQVADEPVLVNSRQGTWTNFVNLADLAALAVPAGFRDDGLPNGITLIGKKFTDYALLE
LANRYFQNIFPNGSRTYGTFTSSSVKPANDQLVGPDYDPSTSIKLAVVGAHLKGLPLH
WQLEKVNATYLCTTKTSKAYQLFALPKNGPVLKPGLRRVQDSNGSQIELEVYSVPKEL
FGAFISMVPEPLGIGSVELESGEWIKSFICEESGYKAKGTVDITKYGGFRAYFEMLKK
KESQKKKLFDTVLIANRGEIAVRIIKTLKKLGIRSVAVYSDPDKYSQHVTDADVSVPL
HGTTAAQTYLDMNKIIDAAKQTNAQAIIPGYGFLSENADFSDACTSAGITFVGPSGDI
IRGLGLKHSARQIAQKAGVPLVPGSLLITSVEEAKKVAAELEYPVMVKSTAGGGGIGL
QKVDSEEDIEHIFETVKHQGETFFGDAGVFLERFIENARHVEVQLMGDGFGKAIALGE
RDCSLQRRNQKVIEETPAPNLPEKTRLALRKAAESLGSLLNYKCAGTVEFIYDEKKDE
FYFLEVNTRLQVEHPITEMVTGLDLVEWMIRIAANDAPDFDSTKVEVNGVSMEARLYA
ENPLKNFRPSPGLLVDVKFPDWARVDTWVKKGTNISPEYDPTLAKIIVHGKDRDDAIS
KLNQALEETKVYGCITNIDYLKSIITSDFFAKAKVSTNILNSYQYEPTAIEITLPGAH
TSIQDYPGRVGYWRIGVPPSGPMDAYSFRLANRIVGNDYRTPAIEVTLTGPSIVFHCE
TVIAITGGTALCTLDGQEIPQHKPVEVKRGSTLSIGKLTSGCRAYLGIRGGIDVPKYL
GSYSTFTLGNVGGYNGRVLKLGDVLFLPSNEENKSVECLPQNIPQSLIPQISETKEWR
IGVTCGPHGSPDFFKPESIEEFFSEKWKVHYNSNRFGVRLIGPKPKWARSNGGEGGMH
PSNTHDYVYSLGAINFTGDEPVIITCDGPSLGGFVCQAVVPEAELWKVGQVKPGDSIQ
FVPLSYESSRSLKESQDVAIKSLDGTKLRRLDSVSILPSFETPILAQMEKVNELSPKV
VYRQAGDRYVLVEYGDNEMNFNISYRIECLISLVKKNKTIGIVEMSQGVRSVLIEFDG
YKVTQKELLKVLVAYETEIQFDENWKITSNIIRLPMAFEDSKTLACVQRYQETIRSSA
PWLPNNVDFIANVNGISRNEVYDMLYSARFMVLGLGDVFLGSPCAVPLDPRHRFLGSK
YNPSRTYTERGAVGIGGMYMCIYAANSPGGYQLVGRTIPIWDKLCLAASSEVPWLMNP
FDQVEFYPVSEEDLDKMTEDCDNGVYKVNIEKSVFDHQEYLRWINANKDSITAFQEGQ
LGERAEEFAKLIQNANSELKESVTVKPDEEEDFPEGAEIVYSEYSGRFWKSIASVGDV
IEAGQGLLIIEAMKAEMIISAPKSGKIIKICHGNGDMVDSGDIVAVIETLA"
gene complement(643007..643078)
/locus_tag="tC(GCA)B"
/db_xref="GeneID:852509"
tRNA complement(643007..643078)
/locus_tag="tC(GCA)B"
/product="tRNA-Cys"
/note="Cysteine tRNA (tRNA-Cys), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006526"
/db_xref="GeneID:852509"
LTR complement(643488..643858)
/note="Ty4 LTR"
/db_xref="SGD:S000006820"
LTR 643859..644002
/note="Ty1 LTR"
/db_xref="SGD:S000006812"
LTR complement(644362..644603)
/note="Ty1 LTR"
/db_xref="SGD:S000006813"
gene 645167..645238
/locus_tag="tE(UUC)B"
/db_xref="GeneID:852510"
tRNA 645167..645238
/locus_tag="tE(UUC)B"
/product="tRNA-Glu"
/note="Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006548"
/db_xref="GeneID:852510"
gene 645550..645978
/gene="ERV15"
/locus_tag="YBR210W"
/db_xref="GeneID:852511"
mRNA 645550..645978
/gene="ERV15"
/locus_tag="YBR210W"
/product="Erv15p"
/transcript_id="NM_001178558.1"
/db_xref="GI:296142874"
/db_xref="GeneID:852511"
CDS 645550..645978
/gene="ERV15"
/locus_tag="YBR210W"
/note="Protein involved in export of proteins from the
endoplasmic reticulum, has similarity to Erv14p"
/codon_start=1
/product="Erv15p"
/protein_id="NP_009769.1"
/db_xref="GI:6319687"
/db_xref="SGD:S000000414"
/db_xref="GeneID:852511"
/translation="MSGTGLSLFVTGLILNCLNSICQIYFTILYGDLEADYINSIELC
KRVNRLSVPEAILQAFISALFLFNGYWFVFLLNVPVLAYNASKVYKKTHLLDATDIFR
KLGRCKIECFLKLGFYLLIFFFYFYRMVTALLENDANLIS"
gene complement(646158..647132)
/gene="AME1"
/locus_tag="YBR211C"
/gene_synonym="ARP100"
/db_xref="GeneID:852512"
mRNA complement(646158..647132)
/gene="AME1"
/locus_tag="YBR211C"
/gene_synonym="ARP100"
/product="Ame1p"
/transcript_id="NM_001178559.3"
/db_xref="GI:398365516"
/db_xref="GeneID:852512"
CDS complement(646158..647132)
/gene="AME1"
/locus_tag="YBR211C"
/gene_synonym="ARP100"
/note="Essential kinetochore protein associated with
microtubules and SPBs; component of the kinetochore
sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p); involved
in spindle checkpoint maintenance; orthologous to human
centromere constitutive-associated network (CCAN) subunit
CENP-U and fission yeast Mis17; relative distribution to
the nucleus increases upon DNA replication stress"
/codon_start=1
/product="Ame1p"
/protein_id="NP_009770.3"
/db_xref="GI:398365517"
/db_xref="SGD:S000000415"
/db_xref="GeneID:852512"
/translation="MDRDTKLAFRLRGSHSRRTDDIDDDVIVFKTPNAVYREENSPIQ
SPVQPILSSPKLANSFEFPITTNNVNAQDRHEHGYQPLDAEDYPMIDSENKSLISESP
QNVRNDEDLTTRYNFDDIPIRQLSSSITSVTTIDVLSSLFINLFENDLIPQALKDFNK
SDDDQFRKLLYKLDLRLFQTISDQMTRDLKDILDINVSNNELCYQLKQVLARKEDLNQ
QIISVRNEIQELKAGKDWHDLQNEQAKLNDKVKLNKRLNDLTSTLLGKYEGDRKIMSQ
DSEDDSIRDDSNILDIAHFVDLMDPYNGLLKKINKINENLSNELQPSL"
gene 647886..649904
/gene="NGR1"
/locus_tag="YBR212W"
/gene_synonym="RBP1"
/db_xref="GeneID:852513"
mRNA 647886..649904
/gene="NGR1"
/locus_tag="YBR212W"
/gene_synonym="RBP1"
/product="Ngr1p"
/transcript_id="NM_001178560.3"
/db_xref="GI:398365522"
/db_xref="GeneID:852513"
CDS 647886..649904
/gene="NGR1"
/locus_tag="YBR212W"
/gene_synonym="RBP1"
/note="RNA binding protein that negatively regulates
growth rate; interacts with the 3' UTR of the
mitochondrial porin (POR1) mRNA and enhances its
degradation; overexpression impairs mitochondrial
function; interacts with Dhh1p to mediate POR1 mRNA decay;
expressed in stationary phase"
/codon_start=1
/product="Ngr1p"
/protein_id="NP_009771.3"
/db_xref="GI:398365523"
/db_xref="SGD:S000000416"
/db_xref="GeneID:852513"
/translation="MMSNVANASQRQENPYIIPLPPSSTVETSTEPPRTLWMGDLDPS
FDEATIEEIWSKLDKKVIVKLIRAKKNLLIPCSSTSSSNNNTSEENAENQQSASNSTD
QLDNSQMININGISFIDPSTTQLHHAGYCFVEFETQKDAKFALSLNATPLPNFYSPTT
NSQTNPTFKRTFRLNWASGATLQSSIPSTPEFSLFVGDLSPTATEADLLSLFQTRFKS
VKTVRVMTDPLTGSSRCFGFVRFGDEDERRRALIEMSGKWFQGRALRVAYATPRNNMM
LQLQEQQQQQQQLQQQHQQLDQEDNNGPLLIKTANNLIQNNSNMLPLNALHNAPPMHL
NEGGISNMRVNDSLPSNTYNTDPTNTTVFVGGLVPKTTEFQLRSLFKPFGPILNVRIP
NGKNCGFVKFEKRIDAEASIQGLQGFIVGGSPIRLSWGRPSSSNAKTNSTIMGASQYM
SSNGLRAPSAASSVDNSKQILEQYAEDKRRLFLHQQQQQQQQQQQDGNFSMEQMAHNN
YYNYNNYDYHRNKNGSHSDLVNLQRSNVPYMQEDGALYPHQYSSPSYSLHPTGNQFSN
ATNNLPQFGNAMSISMQLPNGNSNKTASSMNTNPNTNMIMNSNMNMNMNVNPVPYGMG
NGANMYDVSRMMTPPLNIAPNSNNSKSSIMNKHPNRNNVPPIHPSLLH"
gene 650368..651192
/gene="MET8"
/locus_tag="YBR213W"
/db_xref="GeneID:852514"
mRNA 650368..651192
/gene="MET8"
/locus_tag="YBR213W"
/product="bifunctional precorrin-2
dehydrogenase/sirohydrochlorin ferrochelatase MET8"
/transcript_id="NM_001178561.1"
/db_xref="GI:296142877"
/db_xref="GeneID:852514"
CDS 650368..651192
/gene="MET8"
/locus_tag="YBR213W"
/EC_number="4.99.1.4"
/EC_number="1.3.1.76"
/note="Bifunctional dehydrogenase and ferrochelatase,
involved in the biosynthesis of siroheme, a prosthetic
group used by sulfite reductase; required for sulfate
assimilation and methionine biosynthesis"
/codon_start=1
/product="bifunctional precorrin-2
dehydrogenase/sirohydrochlorin ferrochelatase MET8"
/protein_id="NP_009772.1"
/db_xref="GI:6319690"
/db_xref="SGD:S000000417"
/db_xref="GeneID:852514"
/translation="MVKSLQLAHQLKDKKILLIGGGEVGLTRLYKLIPTGCKLTLVSP
DLHKSIIPKFGKFIQNEDQPDYREDAKRFINPNWDPTKNEIYEYIRSDFKDEYLDLED
ENDAWYIIMTCIPDHPESARIYHLCKERFGKQQLVNVADKPDLCDFYFGANLEIGDRL
QILISTNGLSPRFGALVRDEIRNLFTQMGDLALEDAVVKLGELRRGIRLLAPDDKDVK
YRMDWARRCTDLFGIQHCHNIDVKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS"
gene 651415..652998
/gene="SDS24"
/locus_tag="YBR214W"
/db_xref="GeneID:852515"
mRNA 651415..652998
/gene="SDS24"
/locus_tag="YBR214W"
/product="Sds24p"
/transcript_id="NM_001178562.1"
/db_xref="GI:296142878"
/db_xref="GeneID:852515"
CDS 651415..652998
/gene="SDS24"
/locus_tag="YBR214W"
/note="Protein involved in cell separation during budding;
one of two S. cerevisiae homologs (Sds23p and Sds24p) of
the S. pombe Sds23 protein, which is implicated in
APC/cyclosome regulation; may play an indirect role in
fluid-phase endocytosis; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Sds24p"
/protein_id="NP_009773.1"
/db_xref="GI:6319691"
/db_xref="SGD:S000000418"
/db_xref="GeneID:852515"
/translation="MASTSNTFPPSQSNSSNNLPTSRHASIVEMLSTPPLLPHVQVND
TDDKEQPEESTPPTATAAAPGPGCAATPAPLRDEKPQFKLSAVPMTQTPSQCLSCVHA
QKWQHIPLSQLIEQNKLIFVPGSISVEEAFNTLIKYHLNSIPVESFPGDMNCFTFDYN
DLNSYLLLVLNKITVSNKQLTADCQNGKPVPVGEMVKLTPKNPFYKLPENESLSTVMG
ILGSGVHRVAITNEEMTKVKGILSQRRLIKYLWDNARSFTSLEPLLNSSLQDLHIGVL
NIQSKPTSRQSRVISIQGEEPLIMGLYKMHVERISSIAVIDKQGNLLGNISVTDVKHV
TRTSQYPLLHKTCRHFISVILNSRGLETGKDSFPIFHVYPSSSLARTLAKLVATKSHR
LWIVQPPESSTSASSTNLTAANTAANAVSATAQSSANGATPMSKSSSSTSLNSHSPLM
TAMEDPPSPRSSAIAIPPPSPASSTNTPNLFEKEYRTGKLIGVVSLTDIINLLARKQT
GNKEVDPQSARRQRGSIAM"
gene 653356..655317
/gene="HPC2"
/locus_tag="YBR215W"
/db_xref="GeneID:852516"
mRNA join(653356..653368,653453..655317)
/gene="HPC2"
/locus_tag="YBR215W"
/product="Hpc2p"
/transcript_id="NM_001178563.3"
/db_xref="GI:398365542"
/db_xref="GeneID:852516"
CDS join(653356..653368,653453..655317)
/gene="HPC2"
/locus_tag="YBR215W"
/note="Subunit of the HIR complex, a nucleosome assembly
complex involved in regulation of histone gene
transcription; mutants display synthetic defects with
subunits of FACT, a complex that allows passage of RNA Pol
II through nucleosomes"
/codon_start=1
/product="Hpc2p"
/protein_id="NP_009774.4"
/db_xref="GI:398365543"
/db_xref="SGD:S000000419"
/db_xref="GeneID:852516"
/translation="MDQKAIVLDNSKSGSKQTKSSGKMQTQTDTNAEVLNTDNSIKKE
TGSDSEDLFNKFSNKKTNRKIPNIAEELAKNRNYVKGASPSPIIISGSSSTSPSGPSS
SSTNPMGIPTNRFNKNTVELYQHSPSPVMTTNKTDTEEKRQNNRNMDNKNTPERGSSS
FAAKQLKISSLLTISSNEDSKTLHINDTNGNKNSNAASNNIPSAYAELHTEGNSIESL
IKPPSSPRNKSLTPKVILPTQNMDGTIAKDPHLGDNTPGILIAKTSSPVNLDVESTAQ
SLGKFNKSTNSLKAALTKAPAEKVSLKRSISSVTNSDSNISSSKKPTSEKAKKSSSAS
AILPKPTTTKTSKKAASNSSDSTRKKNASNKTTSAIKKESNAGSKLNTVKKENSSLSS
IKATEKEKDKGGNSTEAKNSTSNVRKEPTAKSPKRLVAAPTVSPPKILQTAETKAKEP
SILIDVPLYQADTNDYLDENGQVIFNLSTLIKEKYHPKSKELAQLKDSKRNLLMQLSD
HSNGSLEKEKDEEGDVIELDDDEDMEEDEGEIDTETNTVTTTISPKKKSHPMKGKNLI
GKYDVEDPFIDDSELLWEEQRAATKDGFFVYFGPLIEKGHYASLERANGTMKRGGVKN
K"
gene complement(655576..657600)
/gene="YBP1"
/locus_tag="YBR216C"
/db_xref="GeneID:852517"
mRNA complement(655576..657600)
/gene="YBP1"
/locus_tag="YBR216C"
/product="Ybp1p"
/transcript_id="NM_001178564.3"
/db_xref="GI:398365552"
/db_xref="GeneID:852517"
CDS complement(655576..657600)
/gene="YBP1"
/locus_tag="YBR216C"
/note="Protein required for oxidation of specific cysteine
residues of the transcription factor Yap1p, resulting in
the nuclear localization of Yap1p in response to stress"
/codon_start=1
/product="Ybp1p"
/protein_id="NP_009775.3"
/db_xref="GI:398365553"
/db_xref="SGD:S000000420"
/db_xref="GeneID:852517"
/translation="MEPIDDILFEVTDAFKTQKEDLLELVTLIDIYGEQVNQEGSYEE
KTRFIETLNTLLEDNPSTTGEIGWDLPKGLLKFLSKDNVDVNGRLGTNMIVQGVMKCF
YAISIQGEPKKCLITGLELLSSLCSKDFSKSDQQNKEDFVDKKANTLPPEGVIENSSN
RKDFPSYGESKSSNEFFLKLKSYILFEFIGASLKRISTLFPSKYLGAAVSTIEKFVYS
HADTFEDALFLLRRVYTFCRNYIPPDPPKDIQLNEDFTREMFDKVVEEESELQVRLLR
RLCTFGISTPIKTVTTNADVKYYCALNQQKFELSAYYTEYLELFCRYYQMAFSLDVDI
EGEFQNVIKECRIIYKSVPQEISAVNDEAKLVLERMVYKLAYTFEVQKAAKEKNVGLD
YNGVILFSGIHYLETNQHLVKEMNITDAIYLYLRFTTPSLYSKVYYNVAVESVSRYWL
WYAITTEPLEDVKKELKNLSVFVTKTLLHVLLQKNCIQVNQQLRMITFTLLTRLLCLI
PEKVAFEFILDVLKTSPLPLAKTSVLCVFKDLSRRRISTKDNDSETDLIVEKLSKLKV
NDSNKAQQSNIRHYIQLDSSKMKAVHDCCLQTIQDSFTADAKKSDILLLLTYLNIFIV
LKKTWDEDLLKIVCSKIDSNLKSVEPDKLPKYKEIVDKNESLNDYFTGIK"
gene 657832..658392
/gene="ATG12"
/locus_tag="YBR217W"
/gene_synonym="APG12"
/db_xref="GeneID:852518"
mRNA 657832..658392
/gene="ATG12"
/locus_tag="YBR217W"
/gene_synonym="APG12"
/product="Atg12p"
/transcript_id="NM_001178565.1"
/db_xref="GI:296142881"
/db_xref="GeneID:852518"
CDS 657832..658392
/gene="ATG12"
/locus_tag="YBR217W"
/gene_synonym="APG12"
/note="Conserved ubiquitin-like modifier involved in
autophagy and the Cvt pathway; conjugated to Atg5p to form
a complex involved in Atg8p lipidation; Atg12p-Atg5p also
forms a complex with Atg16p that is required for
autophagosome formation"
/codon_start=1
/product="Atg12p"
/protein_id="NP_009776.1"
/db_xref="GI:6319694"
/db_xref="SGD:S000000421"
/db_xref="GeneID:852518"
/translation="MSRILESENETESDESSIISTNNGTAMERSRNNQELRSSPHTVQ
NRLELFSRRLSQLGLASDISVDQQVEDSSSGTYEQEETIKTNAQTSKQKSHKDEKNIQ
KIQIKFQPIGSIGQLKPSVCKISMSQSFAMVILFLKRRLKMDHVYCYINNSFAPSPQQ
NIGELWMQFKTNDELIVSYCASVAFG"
gene complement(658707..662249)
/gene="PYC2"
/locus_tag="YBR218C"
/db_xref="GeneID:852519"
mRNA complement(658707..662249)
/gene="PYC2"
/locus_tag="YBR218C"
/product="pyruvate carboxylase 2"
/transcript_id="NM_001178566.1"
/db_xref="GI:296142882"
/db_xref="GeneID:852519"
CDS complement(658707..662249)
/gene="PYC2"
/locus_tag="YBR218C"
/EC_number="6.4.1.1"
/note="Pyruvate carboxylase isoform, cytoplasmic enzyme
that converts pyruvate to oxaloacetate; highly similar to
isoform Pyc1p but differentially regulated; mutations in
the human homolog are associated with lactic acidosis"
/codon_start=1
/product="pyruvate carboxylase 2"
/protein_id="NP_009777.1"
/db_xref="GI:6319695"
/db_xref="SGD:S000000422"
/db_xref="GeneID:852519"
/translation="MSSSKKLAGLRDNFSLLGEKNKILVANRGEIPIRIFRSAHELSM
RTIAIYSHEDRLSMHRLKADEAYVIGEEGQYTPVGAYLAMDEIIEIAKKHKVDFIHPG
YGFLSENSEFADKVVKAGITWIGPPAEVIDSVGDKVSARHLAARANVPTVPGTPGPIE
TVQEALDFVNEYGYPVIIKAAFGGGGRGMRVVREGDDVADAFQRATSEARTAFGNGTC
FVERFLDKPKHIEVQLLADNHGNVVHLFERDCSVQRRHQKVVEVAPAKTLPREVRDAI
LTDAVKLAKVCGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTITEEITGIDIVSAQI
QIAAGATLTQLGLLQDKITTRGFSIQCRITTEDPSKNFQPDTGRLEVYRSAGGNGVRL
DGGNAYAGATISPHYDSMLVKCSCSGSTYEIVRRKMIRALIEFRIRGVKTNIPFLLTL
LTNPVFIEGTYWTTFIDDTPQLFQMVSSQNRAQKLLHYLADLAVNGSSIKGQIGLPKL
KSNPSVPHLHDAQGNVINVTKSAPPSGWRQVLLEKGPSEFAKQVRQFNGTLLMDTTWR
DAHQSLLATRVRTHDLATIAPTTAHALAGAFALECWGGATFDVAMRFLHEDPWERLRK
LRSLVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKDNGVDIFRVFDALNDLEQLK
VGVNAVKKAGGVVEATVCYSGDMLQPGKKYNLDYYLEVVEKIVQMGTHILGIKDMAGT
MKPAAAKLLIGSLRTRYPDLPIHVHSHDSAGTAVASMTACALAGADVVDVAINSMSGL
TSQPSINALLASLEGNIDTGINVEHVRELDAYWAEMRLLYSCFEADLKGPDPEVYQHE
IPGGQLTNLLFQAQQLGLGEQWAETKRAYREANYLLGDIVKVTPTSKVVGDLAQFMVS
NKLTSDDIRRLANSLDFPDSVMDFFEGLIGQPYGGFPEPLRSDVLRNKRRKLTCRPGL
ELEPFDLEKIREDLQNRFGDIDECDVASYNMYPRVYEDFQKIRETYGDLSVLPTKNFL
APAEPDEEIEVTIEQGKTLIIKLQAVGDLNKKTGQREVYFELNGELRKIRVADKSQNI
QSVAKPKADVHDTHQIGAPMAGVIIEVKVHKGSLVKKGESIAVLSAMKMEMVVSSPAD
GQVKDVFIKDGESVDASDLLVVLEEETLPPSQKK"
gene complement(662499..663303)
/locus_tag="YBR219C"
/db_xref="GeneID:852520"
mRNA complement(join(662499..662581,663003..663303))
/locus_tag="YBR219C"
/product="hypothetical protein"
/transcript_id="NM_001178567.3"
/db_xref="GI:398365570"
/db_xref="GeneID:852520"
CDS complement(join(662499..662581,663003..663303))
/locus_tag="YBR219C"
/note="hypothetical protein; YBR219C is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009778.3"
/db_xref="GI:398365571"
/db_xref="SGD:S000000423"
/db_xref="GeneID:852520"
/translation="MTLLNTLSNFGGTWPRLIIMSMINYFTVYQCTIPGTNKVYVTHG
GSMQACTELLNGTVTILRDGYYITNLICIVVGLFLYFGYLKRKILHLQSLPISSWRFF
HFFFTILAVTSRAIYYKSQNWRREC"
gene complement(662995..664677)
/locus_tag="YBR220C"
/db_xref="GeneID:852521"
mRNA complement(662995..664677)
/locus_tag="YBR220C"
/product="hypothetical protein"
/transcript_id="NM_001178568.3"
/db_xref="GI:398365576"
/db_xref="GeneID:852521"
CDS complement(662995..664677)
/locus_tag="YBR220C"
/note="hypothetical protein; YBR220C is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009779.3"
/db_xref="GI:398365577"
/db_xref="SGD:S000000424"
/db_xref="GeneID:852521"
/translation="MEPKRKSGSLAKHDLPQFYLLIMLYLAQGIPVGLAFGTVPFLLK
SLAKETSFTSLGIFSMATYPYSLKIIWSPIVDSLYNKRIGRRRSWIIPVQFVSGFVLW
ALGWCISQGIIFDGVDDAFHNRGNGTLHSVSIKNLTWWFGLLVFLCATQDIAVDGWAL
TILSKESLSYASTAQTIGLNIGYFMSFTIFLSLNSSDFANKYFRNIPLDHGFISLGGY
MKFSGMLYIVITIYIIFCTKEKPYVEYLPKVEPINTSDGGSKPISIEYDDGDVVSTQN
TSSIKYIYRCFIKVLKLKSVRSLAFIHMISKFAFQCNEAATNLKLLEQGFKREDLAVT
VLIDLPFEIIFGYYVVKWSSDKDPMIRDNRRLRNSTGTNKVIKFLVGDAGVLTPWLWG
FLGRLAAAVLGSYVVKQFPKDGEISTGYFCLVIFQHLLGSFMNTVQFIGISAFHTRVA
DPVLGGTYMTLLNTLSNFGGTWPRLIIMSMINYFTVYQCTIPGTNKVYVTHGGSMQAC
TELLNGTVTILRDGYYITNLICIVVGLFLYFGYLKRKILHLQSLPISSWRCT"
gene complement(665153..666253)
/gene="PDB1"
/locus_tag="YBR221C"
/db_xref="GeneID:852522"
mRNA complement(665153..666253)
/gene="PDB1"
/locus_tag="YBR221C"
/product="pyruvate dehydrogenase (acetyl-transferring)
subunit E1 beta"
/transcript_id="NM_001178569.1"
/db_xref="GI:296142885"
/db_xref="GeneID:852522"
CDS complement(665153..666253)
/gene="PDB1"
/locus_tag="YBR221C"
/EC_number="1.2.4.1"
/note="E1 beta subunit of the pyruvate dehydrogenase (PDH)
complex, which is an evolutionarily-conserved
multi-protein complex found in mitochondria"
/codon_start=1
/product="pyruvate dehydrogenase (acetyl-transferring)
subunit E1 beta"
/protein_id="NP_009780.1"
/db_xref="GI:6319698"
/db_xref="SGD:S000000425"
/db_xref="GeneID:852522"
/translation="MFSRLPTSLARNVARRAPTSFVRPSAAAAALRFSSTKTMTVREA
LNSAMAEELDRDDDVFLIGEEVAQYNGAYKVSKGLLDRFGERRVVDTPITEYGFTGLA
VGAALKGLKPIVEFMSFNFSMQAIDHVVNSAAKTHYMSGGTQKCQMVFRGPNGAAVGV
GAQHSQDFSPWYGSIPGLKVLVPYSAEDARGLLKAAIRDPNPVVFLENELLYGESFEI
SEEALSPEFTLPYKAKIEREGTDISIVTYTRNVQFSLEAAEILQKKYGVSAEVINLRS
IRPLDTEAIIKTVKKTNHLITVESTFPSFGVGAEIVAQVMESEAFDYLDAPIQRVTGA
DVPTPYAKELEDFAFPDTPTIVKAVKEVLSIE"
gene 666538..666642
/locus_tag="YBR221W-A"
/db_xref="GeneID:1466450"
mRNA 666538..666642
/locus_tag="YBR221W-A"
/product="hypothetical protein"
/transcript_id="NM_001184644.1"
/db_xref="GI:296142886"
/db_xref="GeneID:1466450"
CDS 666538..666642
/locus_tag="YBR221W-A"
/note="hypothetical protein; identified by expression
profiling and mass spectrometry"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878054.1"
/db_xref="GI:33438772"
/db_xref="SGD:S000028817"
/db_xref="GeneID:1466450"
/translation="MFSHFEVSENRPRKQPRRKRISLGMINTVVSLDR"
gene complement(666720..668351)
/gene="PCS60"
/locus_tag="YBR222C"
/gene_synonym="FAT2"
/db_xref="GeneID:852523"
mRNA complement(666720..668351)
/gene="PCS60"
/locus_tag="YBR222C"
/gene_synonym="FAT2"
/product="Pcs60p"
/transcript_id="NM_001178570.3"
/db_xref="GI:398365584"
/db_xref="GeneID:852523"
CDS complement(666720..668351)
/gene="PCS60"
/locus_tag="YBR222C"
/gene_synonym="FAT2"
/EC_number="6.-.-.-"
/note="Peroxisomal protein that binds AMP and mRNA,
localizes to both the peroxisomal peripheral membrane and
matrix, expression is highly inducible by oleic acid,
similar to E. coli long chain acyl-CoA synthetase"
/codon_start=1
/product="Pcs60p"
/protein_id="NP_009781.3"
/db_xref="GI:398365585"
/db_xref="SGD:S000000426"
/db_xref="GeneID:852523"
/translation="MTSAATVTASFNDTFSVSDNVAVIVPETDTQVTYRDLSHMVGHF
QTMFTNPNSPLYGAVFRQDTVAISMRNGLEFIVAFLGATMDAKIGAPLNPNYKEKEFN
FYLNDLKSKAICVPKGTTKLQSSEILKSASTFGCFIVELAFDATRFRVEYDIYSPEDN
YKRVIYRSLNNAKFVNTNPVKFPGFARSSDVALILHTSGTTSTPKTVPLLHLNIVRST
LNIANTYKLTPLDRSYVVMPLFHVHGLIGVLLSTFRTQGSVVVPDGFHPKLFWDQFVK
YNCNWFSCVPTISMIMLNMPKPNPFPHIRFIRSCSSALAPATFHKLEKEFNAPVLEAY
AMTEASHQMTSNNLPPGKRKPGTVGQPQGVTVVILDDNDNVLPPGKVGEVSIRGENVT
LGYANNPKANKENFTKRENYFRTGDQGYFDPEGFLVLTGRIKELINRGGEKISPIELD
GIMLSHPKIDEAVAFGVPDDMYGQVVQAAIVLKKGEKMTYEELVNFLKKHLASFKIPT
KVYFVDKLPKTATGKIQRRVIAETFAKSSRNKSKL"
gene complement(668663..670297)
/gene="TDP1"
/locus_tag="YBR223C"
/db_xref="GeneID:852525"
mRNA complement(668663..670297)
/gene="TDP1"
/locus_tag="YBR223C"
/product="tyrosyl-DNA phosphodiesterase 1"
/transcript_id="NM_001178571.3"
/db_xref="GI:398365590"
/db_xref="GeneID:852525"
CDS complement(668663..670297)
/gene="TDP1"
/locus_tag="YBR223C"
/EC_number="3.1.4.-"
/note="Tyrosyl-DNA phosphodiesterase I; hydrolyzes 3' and
5'-phosphotyrosyl bonds; involved in the repair of DNA
lesions created by topoisomerase I and topoisomerase II;
mutations in human homolog result in the neurodegenerative
disease SCANI"
/codon_start=1
/product="tyrosyl-DNA phosphodiesterase 1"
/protein_id="NP_009782.3"
/db_xref="GI:398365591"
/db_xref="SGD:S000000427"
/db_xref="GeneID:852525"
/translation="MSRETNFNGTKRKRSDVAEKVAQRWKSVRYSAEMENMAPVNSNN
DSDDCVIVSESKIIDLTNQEQDLSERIETNDTAKGAVFKLMKSDFYEREDFMGEVEDM
ITLKDIFGTETLKRSILFSFQYELDFLLRQFHQNVENITIVGQKGTIMPIEARAMDAT
LAVILKKVKLIEITMPPFASHHTKLIINFYDNGECKIFLPSNNFTSMETNLPQQVCWC
SPLLKIGKEGLPVPFKRSLIEYLNSYHLKDIDELITKSVEEVNFAPLSELEFVYSTPS
KFQSSGLLSFYNKLEKLSAGTSASDTAKHYLCQTSSIGTSLSRARDENLWTHLMIPLF
TGIMSPPAKDTAGRKKAEILPTNSLINEYSQRKIKPYIIFPTEQEFVTSPLKWSSSGW
FHFQYLQKKSYYEMLRNKFKVFYKQDPAMVTRRRGTTPAHSKFYMHCATNSAGPCDAS
QVFKELEWCLYTSANLSQTAWGTVSRKPRNYEAGVLYHSRRLANTRKVTCRTFTRDRR
GCAGNPTHVAVPFTLPVIPYDLAEDECFCLARHEND"
gene 670627..673329
/locus_tag="YBR225W"
/db_xref="GeneID:852526"
mRNA 670627..673329
/locus_tag="YBR225W"
/product="hypothetical protein"
/transcript_id="NM_001178573.1"
/db_xref="GI:296142889"
/db_xref="GeneID:852526"
CDS 670627..673329
/locus_tag="YBR225W"
/note="hypothetical protein; non-essential gene identified
in a screen for mutants affected in mannosylphophorylation
of cell wall components"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009784.1"
/db_xref="GI:6319702"
/db_xref="SGD:S000000429"
/db_xref="GeneID:852526"
/translation="MGSNKEAKNIDSKNDRGLTSITSNKISNLKAHDNHTSSMITEHK
NADKEKGKQEKESRNGTTQSSSSVESHSPQVSHHSDKLSSFDSPLHLPNFRLADDLFS
NSSRRSSDSAASSSVSKLKSAQLSKIGLHHHHTSNNKHSHRSGTPTSEVKANYSPDPS
APRFIVSNMVGNGRGGGGLHGATSNVVKKLHSRKKWDWNTLPASDSSLLIKTVSGNHN
LINICIDGEFKQIMYDPNHNELFNRMDLFLSFNMDSSPEDSLIFAKKRLRSYIDFLTK
YLESRKYAFECYPFNIENIINIETEVKCFPSFDPLKDYSEIESLIQLWLAQSQKFLLQ
SNSFFFSSEVVEELIKRKPTTRQHSNPTISTTSNKISDPTLYIQQLDIEANSPRPVIS
DPLDEIDILLIRPLHKTLGGWQLAYDEPSLNIADFALDLSPWMIDSSDNDAQNKNASE
IAPEYLTNLQNYLPRKGSRAKIVSDEQEVIELNSSNASEYMYDCMNRKFFTDDAKERI
SRNNFNQGVEEDPLNDQFASSRSLSLPSSGADAVKRKKSPTKATKKSGFVNFFKRKHS
QLASTSHTTSPSVSPSISSSSSPKIQPQSHISSPPRTEKAPHVKSANQAHQNEWLENF
FCRTLNNYKEIDLPTQFILPKEVKRSSNAQLQPEDEPPLSSPISSNSDNSFPNEGLDR
AKSAAIYGKEYLKLRLPFASDTIPAVICPWVWTSLSYYKWKALLREIYRSIIPGGYAL
AIVPDLRISNTYYTGILGNADAEKANNSSEEFLTTKERDKTFDAMAIDAINKGLHIHP
TKHLTRTFKDVGFTGIKSSVLSLKTGDFKTDMGFLNEFNSLDMWDYMLRRQLPDSSCP
PKDTDPTTLFKRYVEEHIGKIDDNAGCFRTLYVVAQKPKLPYTK"
gene complement(673572..675134)
/gene="MCX1"
/locus_tag="YBR227C"
/db_xref="GeneID:852528"
mRNA complement(673572..675134)
/gene="MCX1"
/locus_tag="YBR227C"
/product="Mcx1p"
/transcript_id="NM_001178575.1"
/db_xref="GI:296142890"
/db_xref="GeneID:852528"
CDS complement(673572..675134)
/gene="MCX1"
/locus_tag="YBR227C"
/note="Mitochondrial matrix protein; putative ATP-binding
chaperone with non-proteolytic function; similar to
bacterial ClpX proteins"
/codon_start=1
/product="Mcx1p"
/protein_id="NP_009786.1"
/db_xref="GI:6319704"
/db_xref="SGD:S000000431"
/db_xref="GeneID:852528"
/translation="MLKSASQNFFRAYSSRIGRYAATASGKLAQSRLSNIPTPKALKK
FLDEYIVGQEIGKKVLSVAVYNHYLRINDKQKKGELQRQRELMEREKIADDRDEPIFS
GNSESKAGWRNLQRQFNLAGREVDEDLELSKSNVLVVGPSGSGKTLLATTLAKILNVP
IAITDCTQLTQAGYIGEDVEVCIERLLVNAEFDVARAEKGIIVLDEIDKLAKPAASIG
TKDVSGEGVQQSLLKIIEGHKVEITVKRPVKHDIDGQKNQTTTKKDEVFVVDTSNILF
MIMGAFVGLDKHIVKRIEDMKKIQKAGESVESSNSKEVEKERAKKFRFSNTLEQVELD
NGKKVCALDLTTPTDLVSFGLIPELIGRVPIITALQPLQRDDLFHILKEPKNALLDQY
EYIFKQFGVRLCVTQKALKKVAQFALKEGTGARGLRGIMERLLLNVNYDCPGSNIAYV
LIDEATVDSLQETEHSLASQVDVKYYSGDEKDSLIRDVSEEDKKLGVMLEKELGHSAN
IHTPTIPKRSLT"
gene 675313..676227
/gene="SLX1"
/locus_tag="YBR228W"
/db_xref="GeneID:852529"
mRNA 675313..676227
/gene="SLX1"
/locus_tag="YBR228W"
/product="Slx1p"
/transcript_id="NM_001178576.3"
/db_xref="GI:398365606"
/db_xref="GeneID:852529"
CDS 675313..676227
/gene="SLX1"
/locus_tag="YBR228W"
/EC_number="3.6.1.-"
/note="Subunit of a complex, with Slx4p, that hydrolyzes
5' branches from duplex DNA in response to stalled or
converging replication forks; function overlaps with that
of Sgs1p-Top3p"
/codon_start=1
/product="Slx1p"
/protein_id="NP_009787.3"
/db_xref="GI:398365607"
/db_xref="SGD:S000000432"
/db_xref="GeneID:852529"
/translation="MSQKIQQHQFPDFYCCYLLQSINKRQSFYVGSTPNPVRRLRQHN
GKLAVGGAYRTKRDGSRPWEMIMIVRGFPSKIAALQFEHAWQHGYQTHYIAEKDRVVK
HKAGGRTLHHKVALMKLLLKHEFFQRMNLIVEVFNIKAWEVWKQDKFFIERDRFPINI
QINENALEEPKEKTVDVLMDHSDENLKVVEAVYTKVIENERNIFETFEKKLTTGVVRC
EICEKEIDYTSEEQNLKPFVALCNNKDCGCVNHLKCLHRYFLDDEQLMVGRRNLIPRG
GKCPKCDMFCDWTTLVKFSTRMKLAHGK"
gene complement(676357..679221)
/gene="ROT2"
/locus_tag="YBR229C"
/gene_synonym="GLS2"
/db_xref="GeneID:852530"
mRNA complement(676357..679221)
/gene="ROT2"
/locus_tag="YBR229C"
/gene_synonym="GLS2"
/product="Rot2p"
/transcript_id="NM_001178577.3"
/db_xref="GI:398365610"
/db_xref="GeneID:852530"
CDS complement(676357..679221)
/gene="ROT2"
/locus_tag="YBR229C"
/gene_synonym="GLS2"
/EC_number="3.2.1.-"
/note="Glucosidase II catalytic subunit required for
normal cell wall synthesis; mutations in rot2 suppress
tor2 mutations, and are synthetically lethal with rot1
mutations"
/codon_start=1
/product="Rot2p"
/protein_id="NP_009788.3"
/db_xref="GI:398365611"
/db_xref="SGD:S000000433"
/db_xref="GeneID:852530"
/translation="MVLLKWLVCQLVFFTAFSHAFTDYLLKKCAQSGFCHRNRVYAEN
IAKSHHCYYKVDAESIAHDPLENVLHATIIKTIPRLEGDDIAVQFPFSLSFLQDHSVR
FTINEKERMPTNSSGLLISSQRFNETWKYAFDKKFQEEANRTSIPQFHFLKQKQTVNS
FWSKISSFLSLSNSTADTFHLRNGDVSVEIFAEPFQLKVYWQNALKLIVNEQNFLNIE
HHRTKQENFAHVLPEETTFNMFKDNFLYSKHDSMPLGPESVALDFSFMGSTNVYGIPE
HATSLRLMDTSGGKEPYRLFNVDVFEYNIGTSQPMYGSIPFMFSSSSTSIFWVNAADT
WVDIKYDTSKNKTMTHWISENGVIDVVMSLGPDIPTIIDKFTDLTGRPFLPPISSIGY
HQCRWNYNDEMDVLTVDSQMDAHMIPYDFIWLDLEYTNDKKYFTWKQHSFPNPKRLLS
KLKKLGRNLVVLIDPHLKKDYEISDRVINENVAVKDHNGNDYVGHCWPGNSIWIDTIS
KYGQKIWKSFFERFMDLPADLTNLFIWNDMNEPSIFDGPETTAPKDLIHDNYIEERSV
HNIYGLSVHEATYDAIKSIYSPSDKRPFLLTRAFFAGSQRTAATWTGDNVANWDYLKI
SIPMVLSNNIAGMPFIGADIAGFAEDPTPELIARWYQAGLWYPFFRAHAHIDTKRREP
YLFNEPLKSIVRDIIQLRYFLLPTLYTMFHKSSVTGFPIMNPMFIEHPEFAELYHIDN
QFYWSNSGLLVKPVTEPGQSETEMVFPPGIFYEFASLHSFINNGTDLIEKNISAPLDK
IPLFIEGGHIITMKDKYRRSSMLMKNDPYVIVIAPDTEGRAVGDLYVDDGETFGYQRG
EYVETQFIFENNTLKNVRSHIPENLTGIHHNTLRNTNIEKIIIAKNNLQHNITLKDSI
KVKKNGEESSLPTRSSYENDNKITILNLSLDITEDWEVIF"
gene complement(679549..680050)
/gene="OM14"
/locus_tag="YBR230C"
/db_xref="GeneID:852531"
mRNA complement(join(679549..679942,680040..680050))
/gene="OM14"
/locus_tag="YBR230C"
/product="Om14p"
/transcript_id="NM_001178578.1"
/db_xref="GI:296142893"
/db_xref="GeneID:852531"
CDS complement(join(679549..679942,680040..680050))
/gene="OM14"
/locus_tag="YBR230C"
/note="Integral mitochondrial outer membrane protein;
abundance is decreased in cells grown in glucose relative
to other carbon sources; appears to contain 3
alpha-helical transmembrane segments; ORF encodes a
97-basepair intron"
/codon_start=1
/product="Om14p"
/protein_id="NP_009789.1"
/db_xref="GI:6319707"
/db_xref="SGD:S000000434"
/db_xref="GeneID:852531"
/translation="MSATAKHDSNASPNSDSEDGHHHNNKKECAIEYLKARLNSASAV
ACGYLQAFVSKTQDFAKVCFLELQNPVVLVNLLLHSSVVCYLCNGYANHNARFLKGKP
NSTVLATTAGALGLLTLDGIISKKYYSRYDKK"
gene 680362..680562
/locus_tag="YBR230W-A"
/db_xref="GeneID:2777172"
mRNA 680362..680562
/locus_tag="YBR230W-A"
/product="hypothetical protein"
/transcript_id="NM_001184673.1"
/db_xref="GI:296142894"
/db_xref="GeneID:2777172"
CDS 680362..680562
/locus_tag="YBR230W-A"
/note="hypothetical protein; YBR230W-A has a paralog,
COQ8, that arose from the whole genome duplication"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_001018029.1"
/db_xref="GI:63148619"
/db_xref="SGD:S000029722"
/db_xref="GeneID:2777172"
/translation="MRNELYQLWCVASAARGVAKSSFVRANSAMCEYVRTSNVLSRWT
RDRQWEAAKALSQRVKKEYAAN"
gene complement(680688..681862)
/locus_tag="LSR1"
/db_xref="GeneID:9164871"
ncRNA complement(680688..681862)
/locus_tag="LSR1"
/ncRNA_class="snRNA"
/product="LSR1"
/note="U2 spliceosomal RNA (U2 snRNA), component of the
spliceosome; pairs with the branchpoint sequence;
functionally equivalent to mammalian U2 snRNA;
stress-induced pseudouridylations at positions 56 and 93
may contribute to regulation of splicing"
/db_xref="SGD:S000006478"
/db_xref="GeneID:9164871"
gene complement(682179..683090)
/gene="SWC5"
/locus_tag="YBR231C"
/gene_synonym="AOR1"
/db_xref="GeneID:852532"
mRNA complement(682179..683090)
/gene="SWC5"
/locus_tag="YBR231C"
/gene_synonym="AOR1"
/product="Swc5p"
/transcript_id="NM_001178579.3"
/db_xref="GI:398365630"
/db_xref="GeneID:852532"
CDS complement(682179..683090)
/gene="SWC5"
/locus_tag="YBR231C"
/gene_synonym="AOR1"
/note="Component of the SWR1 complex; complex exchanges
histone variant H2AZ (Htz1p) for chromatin-bound histone
H2A; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="Swc5p"
/protein_id="NP_009790.3"
/db_xref="GI:398365631"
/db_xref="SGD:S000000435"
/db_xref="GeneID:852532"
/translation="MPEVETKIIPNEKEDEDEDGYIEEEDEDFQPEKDKLGGGSDDSD
ASDGGDDYDDGVNRDKGRNKVDYSRIESESGGLIKTRRARQAEEEYAKTHKYESLTVE
SIPAKVNSIWEELQEASKNRLLSSSGKVGSVLDGSKEARSTTAAQQEDKILIERNYKF
AGETVHEKKWVSRSSAEGQEYLNSLKFKQQAPAAPVQLEKAVRTKSNESRQHLRRPLK
RPPLLEQIISGGLRPKLTTLEKSQLDWASYVDRAGLNDELVLHNKDGFLARQEFLQRV
GSAEDERYKELRRQQLAQQLQQDSEAS"
gene 683428..684669
/gene="PBP2"
/locus_tag="YBR233W"
/gene_synonym="HEK1"
/db_xref="GeneID:852533"
mRNA 683428..684669
/gene="PBP2"
/locus_tag="YBR233W"
/gene_synonym="HEK1"
/product="Pbp2p"
/transcript_id="NM_001178581.3"
/db_xref="GI:398365638"
/db_xref="GeneID:852533"
CDS 683428..684669
/gene="PBP2"
/locus_tag="YBR233W"
/gene_synonym="HEK1"
/note="RNA binding protein; has similarity to mammalian
heterogeneous nuclear RNP K protein, involved in the
regulation of telomere position effect and telomere
length; relative distribution to the nucleus increases
upon DNA replication stress"
/codon_start=1
/product="Pbp2p"
/protein_id="NP_009792.3"
/db_xref="GI:398365639"
/db_xref="SGD:S000000437"
/db_xref="GeneID:852533"
/translation="MSTETTKPSITTTPTTVLVSPNTLKRKKGEDTSEEQLEAEIKRV
ALKDADSHSDNDHDSPDNVPSDVHLRMLCLVKHASLIVGHKGATISRIKSETSARINI
SNNIRGVPERIVYVRGTCDDVAKAYGMIVRALLEEHGNEDNGEDIEISINLLIPHHLM
GCIIGKRGSRLREIEDLSAAKLFASPNQLLLSNDRILTINGVPDAIHIATFYISQTLL
NFQMESPQKNVKRSIYYQPTQFNSVLIDHSQPNTIFHQRNHQYHPSDKLLSYKPNKNL
PISSTLLSMATPQYTTASVANATAFQPNFVIPNVTVLDGPVISPAPGNHLLMNFVQQE
IFIDEKFVGNVIGKDGKHINSVKESTGCSIIIQDPVEGSSERRLTIRGTFMASQAAIM
LISNKIEIDRSNAERKRRSPL"
gene 684977..685261
/gene="DAD3"
/locus_tag="YBR233W-A"
/db_xref="GeneID:852535"
mRNA 684977..685261
/gene="DAD3"
/locus_tag="YBR233W-A"
/product="Dad3p"
/transcript_id="NM_001184461.1"
/db_xref="GI:296142897"
/db_xref="GeneID:852535"
CDS 684977..685261
/gene="DAD3"
/locus_tag="YBR233W-A"
/note="Essential subunit of the Dam1 complex (aka DASH
complex), couples kinetochores to the force produced by MT
depolymerization thereby aiding in chromosome segregation;
is transferred to the kinetochore prior to mitosis"
/codon_start=1
/product="Dad3p"
/protein_id="NP_631876.1"
/db_xref="GI:21450619"
/db_xref="SGD:S000007595"
/db_xref="GeneID:852535"
/translation="MEHNLSPLQQEVLDKYKQLSLDLKALDETIKELNYSQHRQQHSQ
QETVSPDEILQEMRDIEVKIGLVGTLLKGSVYSLILQRKQEQESLGSNSK"
gene complement(685438..686592)
/gene="ARC40"
/locus_tag="YBR234C"
/db_xref="GeneID:852536"
mRNA complement(685438..686592)
/gene="ARC40"
/locus_tag="YBR234C"
/product="Arc40p"
/transcript_id="NM_001178582.1"
/db_xref="GI:296142898"
/db_xref="GeneID:852536"
CDS complement(685438..686592)
/gene="ARC40"
/locus_tag="YBR234C"
/note="Subunit of the ARP2/3 complex, which is required
for the motility and integrity of cortical actin patches"
/codon_start=1
/product="Arc40p"
/protein_id="NP_009793.1"
/db_xref="GI:6319711"
/db_xref="SGD:S000000438"
/db_xref="GeneID:852536"
/translation="MSFSNSKDKSVVAVYKLVKAPIYSHCFSQDKSILAVTCETDCLV
YRVSNNTPPVLFATLKDHDKTITAVDISIHGRIVTCSQDRNAYVWEPLSDGTYKPTLV
LLRINRAATSVTWAPNGYKFAVGSSARIIAVCYYEHENNWWVSKHIKKPIKSTINCLS
WHANGVLLAAGGTDGFMRVFSGFIKGLDSKESVAGSPWGQKFPFGCLIREWYQGSYIH
DVEWRSQMERIAYVAHDGTLNVVDYQSPVQSVNAPEGLPYRSLVWINDHEIVCGGYSC
HPVLFSEASEGWKFAKNLDKSDNNKSSALTASGNTDELSGNNDESSTFGISALRKFKE
LDLKGKVSTDVQESAHENAIVELRPFAESNGQITQVSSCGLDGKIVIYTI"
gene 686901..690263
/gene="VHC1"
/locus_tag="YBR235W"
/db_xref="GeneID:852537"
mRNA 686901..690263
/gene="VHC1"
/locus_tag="YBR235W"
/product="Vhc1p"
/transcript_id="NM_001178583.3"
/db_xref="GI:398365652"
/db_xref="GeneID:852537"
CDS 686901..690263
/gene="VHC1"
/locus_tag="YBR235W"
/note="Vacuolar membrane cation-chloride cotransporter
(CCC); likely mediates K+ and Cl- cotransport into the
vacuole; has a role in potassium homeostasis and salt
tolerance; similar to mammalian electroneutral
Na(+)-(K+)-C1- cotransporter family"
/codon_start=1
/product="Vhc1p"
/protein_id="NP_009794.3"
/db_xref="GI:398365653"
/db_xref="SGD:S000000439"
/db_xref="GeneID:852537"
/translation="MVSRFYQIPGTHRPSSAISSSNESSSLLSARRISQTYFNYQATP
ECQKVSSKYDPDNPNKDKLGTYDGVFVPTALNVLSILMFLRFGFILGQLGIICTIGLL
LLSYTINLLTTLSISAISTNGTVRGGGAYYMISRSLGPEFGGSIGLVFFLGQVFNAGM
NAVGIIEPLLYNLGYSAQGEPPAALGELLPRGHWHEFTYATVILFLCFSVAFVGSQTV
SRAGNILFLVLAASIFSIPLSALIRSPFTEGGISYTGPSWQTFHDNLLPHLTKGAAGS
LLKGKETFNDLFGVFFPATAGIFAGAGMSSELRKPSKSIPKGTLWGLLFTFICYAVVV
FSMGCSIPRRSLYDEVQIIQTISSVQWVIFMGEMATSLFSIIVGMLGAAYVLEAIAKD
NIIPGLEIFAHSPLYSLIFTWILTQLCLFSDVNKIATFITMTFLMTFVVMNLACFLLG
ISSAPNFRPSFKYFNRYTTAIGALLSVVAMLIVDGISASVLFLAMILLFLFIHYFSPP
KSWGDVSQSLIYHQVRKYLLRLRQDNIKYWRPQILLFVDNPRTSWNLIRFCNHLKKGG
LYILGHVAVTADFPKQLNELKTQQKAWMKIRDMAAIKAFVQVGTGPSLIWGIRNVFIG
SGLGGMKPNITVVGFFDLESYRKHIPQSRSQNNLQKQVEIKATVPRSTCSDVKINVPL
PTDECKNETKVNVQQWVQIVEDLSLMQSNIAIAHGFKNLEIPNKRDSCFPKKTIDLYP
IQMCGKVEAKGDQPAAITTNFDTYTLILQLAAILVTVPEWKRTHSLRVILFVEQEYHR
TNETQRMKKLLQVLRIDAEVLVVSLDQFRVYNTIVKGDPIVFDYVNSKLADNEWWKDL
VEARDTLKPKRRFSTIEPQTIAKQFTQSRKYTSGVQKLGVSFTMNTRMPTNRIDTPCE
SEDSDLDTDLTSIRDAFSASTNISVGKDLTTKSKTGSDRTNLLVKNLQSDVSTQSLRP
VFSSNTLPRTRVVEDGTGEQPTLIPIAEPDLSNGNGTGSGIGNGNKLKKPVLPELSPC
CSKDSLVTAMQNLGFNDLPSTAQHLVLNDVMTQMSKSSDLIFSTLPVPALGTHEDHDA
SLQYVEDLDIWLEGLPPCMLINSQTMTVTTAL"
gene complement(690383..691693)
/gene="ABD1"
/locus_tag="YBR236C"
/db_xref="GeneID:852538"
mRNA complement(690383..691693)
/gene="ABD1"
/locus_tag="YBR236C"
/product="Abd1p"
/transcript_id="NM_001178584.3"
/db_xref="GI:398365662"
/db_xref="GeneID:852538"
CDS complement(690383..691693)
/gene="ABD1"
/locus_tag="YBR236C"
/EC_number="2.1.1.56"
/note="Methyltransferase, catalyzes the transfer of a
methyl group from S-adenosylmethionine to the GpppN
terminus of capped mRNA"
/codon_start=1
/product="Abd1p"
/protein_id="NP_009795.3"
/db_xref="GI:398365663"
/db_xref="SGD:S000000440"
/db_xref="GeneID:852538"
/translation="MSTKPEKPIWMSQEDYDRQYGSITGDESSTVSKKDSKVTANAPG
DGNGSLPVLQSSSILTSKVSDLPIEAESGFKIQKRRHERYDQEERLRKQRAQKLREEQ
LKRHEIEMTANRSINVDQIVREHYNERTIIANRAKRNLSPIIKLRNFNNAIKYMLIDK
YTKPGDVVLELGCGKGGDLRKYGAAGISQFIGIDISNASIQEAHKRYRSMRNLDYQVV
LITGDCFGESLGVAVEPFPDCRFPCDIVSTQFCLHYAFETEEKARRALLNVAKSLKIG
GHFFGTIPDSEFIRYKLNKFPKEVEKPSWGNSIYKVTFENNSYQKNDYEFTSPYGQMY
TYWLEDAIDNVPEYVVPFETLRSLADEYGLELVSQMPFNKFFVQEIPKWIERFSPKMR
EGLQRSDGRYGVEGDEKEAASYFYTMFAFRKVKQYIEPESVKPN"
gene 691969..694518
/gene="PRP5"
/locus_tag="YBR237W"
/gene_synonym="RNA5"
/db_xref="GeneID:852539"
mRNA 691969..694518
/gene="PRP5"
/locus_tag="YBR237W"
/gene_synonym="RNA5"
/product="Prp5p"
/transcript_id="NM_001178585.1"
/db_xref="GI:296142901"
/db_xref="GeneID:852539"
CDS 691969..694518
/gene="PRP5"
/locus_tag="YBR237W"
/gene_synonym="RNA5"
/EC_number="3.6.1.-"
/note="RNA helicase in the DEAD-box family, necessary for
prespliceosome formation, bridges U1 and U2 snRNPs and
enables stable U2 snRNP association with intron RNA"
/codon_start=1
/product="DEAD-box RNA helicase PRP5"
/protein_id="NP_009796.1"
/db_xref="GI:6319714"
/db_xref="SGD:S000000441"
/db_xref="GeneID:852539"
/translation="METIDSKQNINRESLLEERRKKLAKWKQKKAQFDAQKEHQTSRN
DIVTNSLEGKQTTEKFTERQERVKEELRKRKNEFRKSDEPVSVKPSKKKSKRSKVKKK
ISFDFSDDDDSEIGVSFRSKEHIQKAPEHDNEKDPLDEFMTSLKEEKMSNSKGMYDRG
DILDVEDQLFELGGTDDEDVEDNTDNSNIAKIAKLKAKKRVKQIYYSPEELEPFQKNF
YIESETVSSMSEMEVEELRLSLDNIKIKGTGCPKPVTKWSQLGLSTDTMVLITEKLHF
GSLTPIQSQALPAIMSGRDVIGISKTGSGKTISYLLPLLRQVKAQRPLSKHETGPMGL
ILAPTRELALQIHEEVTKFTEADTSIRSVCCTGGSEMKKQITDLKRGTEIVVATPGRF
IDILTLNDGKLLSTKRITFVVMDEADRLFDLGFEPQITQIMKTVRPDKQCVLFSATFP
NKLRSFAVRVLHSPISITINSKGMVNENVKQKFRICHSEDEKFDNLVQLIHERSEFFD
EVQSENDGQSSDVEEVDAKAIIFVSSQNICDFISKKLLNAGIVTCAIHAGKPYQERLM
NLEKFKREKNSILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQYVHTTGRTARGSRSGT
AITLLLHDELSGAYILSKAMRDEEIKALDPLQAKELQEMSAKFESGMKKGKFRLSKGF
GGKGLENIKSKREEAQNKDLELKKNDKRSDDLEKKISNPREGHDSVSESSALIPRLNY
ELFKESTDGSIIFYAKVYINDLPQIVRWEATKNTTLLFIKHETGCSITNKGKFYPEGK
EPKNENDEPKLYLLIEGQDEKDIQLSIELLEQKVKEGVVKAASLSLKSTKY"
gene complement(695107..697302)
/locus_tag="YBR238C"
/db_xref="GeneID:852540"
mRNA complement(695107..697302)
/locus_tag="YBR238C"
/product="hypothetical protein"
/transcript_id="NM_001178586.1"
/db_xref="GI:296142902"
/db_xref="GeneID:852540"
CDS complement(695107..697302)
/locus_tag="YBR238C"
/note="Mitochondrial membrane protein with similarity to
Rmd9p; not required for respiratory growth but causes a
synthetic respiratory defect in combination with rmd9
mutations; transcriptionally up-regulated by TOR; deletion
increases life span"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009797.1"
/db_xref="GI:6319715"
/db_xref="SGD:S000000442"
/db_xref="GeneID:852540"
/translation="MIRLAQQTQVLKGKPPNQFVPHPTKNSLTHPMKFNGTIAMEHHE
HNYAIPYTPATFNNPALATYQVSPANHFVPHFGGNIGANNNNHLAQNNSNNSNNHHNN
NRNHHHNNNRNHHQNNHNHSKYNNSNQGNSISPDSPWFHKVCAFEDCVSQTLYMSQTP
RRQNMKHHSEHPNSNANPLFWDSIGRAMGLYHDLLTTPELNSDRVSKLVHLLHNGLRA
NRNQLTRMNKKPDYDSQSFHKEMTNYLCKSLREISEDVLNGKVELNEYGAMHLITAFK
ELLLFEEAVDIWKAAINGQNTYTSNIFLNPRVVGVILPILYDNGVSYPEIQALYEKSS
SMINYFHPNLSVGMIRASLSASENDMALKLFQKLCQESTEMKYGYLIETHLSFIGECK
DLNVAQTFFDKALNDEMPYKIDLQVSYVKSFLRNIWSQTRDFNHIYQIWYKSSLHYGR
NVNHGISSSLNDTFFDIFFENYAVDKMQGFQTLQNIIQTYNNIKHIDEPFFNIILAKC
TVWHDRSILEYIDKSYEAYHIPKTIVAYRILLKSMGSVDDASNAEILQRWMDLIRKSD
EIGQRFIANADWAALRDATVTWTQNDRDSKKSNMNSTQISRTATPSPSLTPMDTPAPE
HLFNNPQNPMDFYSHPALQAATASGAFDEFAAEAASSSIPVDGRMVLYLKIVKRYSPY
CRDSRQLARLTTGTAVKYSVLQEVLNQFQTLIVNDIPIPELHNLKPTCV"
gene complement(698354..699943)
/gene="ERT1"
/locus_tag="YBR239C"
/db_xref="GeneID:852541"
mRNA complement(698354..699943)
/gene="ERT1"
/locus_tag="YBR239C"
/product="Ert1p"
/transcript_id="NM_001178587.3"
/db_xref="GI:398365676"
/db_xref="GeneID:852541"
CDS complement(698354..699943)
/gene="ERT1"
/locus_tag="YBR239C"
/note="Transcriptional regulator of nonfermentable carbon
utilization; GFP-fusion protein localizes to cytoplasm,
nucleus; null mutation affects periodicity of
transcriptional and metabolic oscillation; plays role in
restricting Ty1 transposition"
/codon_start=1
/product="Ert1p"
/protein_id="NP_009798.3"
/db_xref="GI:398365677"
/db_xref="SGD:S000000443"
/db_xref="GeneID:852541"
/translation="MCTPDENDYKTSTDPDTSANTNHTLEKKKRKKRKNTNVACVNCS
RLHVSCEAKRPCLRCISKGLTATCVDAPRKKSKYLAGIPNRELPMNIQPDLPPRKIMI
PIYNNSSNSSLNVNNMGEQQKFTSPQHIVHKAKFLSNAADSEYSILSNIIYQDTLSNK
IPIDILYSNTNSTSNSTIGNSSNNSPTGTNTSPEETEMEKIRQLYSEQRANIPPHPYP
SSNQNVYSILLGPNSAKIVASQVNLFANHFPLVPVDSADNSLNFKRLLPRDPSEKSSQ
INWDSSINQYYLNSETVTFPELAIPLKRRKNHLVSVSLESCSPDAANIKSNVEWEHSL
RYSTPMEIYTSINAPFSHTPGFHHLLVYLKHRFNQQDLVKMCRSIAEFRPIFIACSVT
LTEEDMIFMEQCYQRTLLEYVKFIAQIGTPTCIWRRNGQISYVNEEFEILCGWTREEL
LNKMTFIVEIMDDESVRDYFKTLSKVAYRDFRGSEKMKVCRLLSPIKGKIIHCCCMWT
LKRDVSGLPLMILGNFMPILN"
gene complement(700490..701842)
/gene="THI2"
/locus_tag="YBR240C"
/gene_synonym="PHO6"
/db_xref="GeneID:852542"
mRNA complement(700490..701842)
/gene="THI2"
/locus_tag="YBR240C"
/gene_synonym="PHO6"
/product="Thi2p"
/transcript_id="NM_001178588.3"
/db_xref="GI:398365684"
/db_xref="GeneID:852542"
CDS complement(700490..701842)
/gene="THI2"
/locus_tag="YBR240C"
/gene_synonym="PHO6"
/note="Transcriptional activator of thiamine biosynthetic
genes; interacts with regulatory factor Thi3p to control
expression of thiamine biosynthetic genes with respect to
thiamine availability; acts together with Pdc2p to respond
to thiaminediphosphate demand, possibly as related to
carbon source availability; zinc finger protein of the
Zn(II)2Cys6 type"
/codon_start=1
/product="Thi2p"
/protein_id="NP_009799.3"
/db_xref="GI:398365685"
/db_xref="SGD:S000000444"
/db_xref="GeneID:852542"
/translation="MVNSKRQQRSKKVASSSKVPPTKGRTFTGCWACRFKKRRCDENR
PICSLCAKHGDNCSYDIRLMWLEENIYKVRKHSLISSLQARKSKSKPLCQKISKSRFK
QMTHFRQLSPPTSDCEDSVHEASKETTLPNDNTFTISVRRLKIYNNAVASVFGSMTNR
DYTQKRIDKKLDELLNMVENDISVVNLNCSKHGPYSVFRANPAAVTSALTDQLPSPGH
SMSSAEETTTAALSSPPEDSTSLIDIIQGKIFGILWFNCYGNMILNRQEYTTWFINKM
RNSLTTEFIRFLGKIIDDPDINMASCLFKECIARWSCVDWQSIAITMLVIIHGYTCPN
LTKLLRVWFLQQKLLRFSMYPLVNFIINNTQDLDVLYHCNGLLGNADLFEDPYQDELT
SELHVLVTERLVNSWKDTILQQLCSCQDTTLSCSQLRYWQLQLKCNQQFYKDVYAMQD
"
gene complement(702589..704055)
/locus_tag="YBR241C"
/db_xref="GeneID:852543"
mRNA complement(702589..704055)
/locus_tag="YBR241C"
/product="hypothetical protein"
/transcript_id="NM_001178589.1"
/db_xref="GI:296142905"
/db_xref="GeneID:852543"
CDS complement(702589..704055)
/locus_tag="YBR241C"
/note="Putative transporter, member of the sugar porter
family; green fluorescent protein (GFP)-fusion protein
localizes to the vacuolar membrane; YBR241C is not an
essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009800.1"
/db_xref="GI:6319718"
/db_xref="SGD:S000000445"
/db_xref="GeneID:852543"
/translation="MAETERLMPNGGSRETKPLITGHLILGTIVACLGSIQYGYHIAE
LNAPQEFLSCSRFEAPDENISYDDTWVGQHGLKQCIALTDSQYGAITSIFSIGGLFGS
YYAGNWANRYGRKYVSMGASAMCMVSSLLLFFSNSYLQLLFGRFLVGMSCGTAIVITP
LFINEIAPVEWRGAMGSMNQVSINLGILLTQTLALKYADSYNWRWLLFSGSVIAVANI
LAWLKVDESPRWLVSHGFVSEAETALFKLRPGTYQQAKQEIQDWQRSHGHNRDPESSE
ETHSGPTLWQYVTDPSYKKPRTVILAILSCQQFCGINSIIFYGVKVIGKILPDYSIQV
NFAISILNVVVTLAASAIIDHVGRRPLLLASTTVMTAMSLLISVGLTLSVSFLLVTAT
FVYIAAFAIGLGPIPFLIIGELSYPQDAATAQSFGTVCNWLATFIVGYLFPIGHGLMG
GYVFAIFAAIAAMFATYVYKRVPETKGKTTYSEVWAGY"
rep_origin 704296..704566
/note="ARS222;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118352"
gene 704670..705386
/locus_tag="YBR242W"
/db_xref="GeneID:852544"
mRNA 704670..705386
/locus_tag="YBR242W"
/product="hypothetical protein"
/transcript_id="NM_001178590.1"
/db_xref="GI:296142906"
/db_xref="GeneID:852544"
CDS 704670..705386
/locus_tag="YBR242W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and
nucleus; YBR242W is not an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009801.1"
/db_xref="GI:6319719"
/db_xref="SGD:S000000446"
/db_xref="GeneID:852544"
/translation="MTATITNKKSCSGSVEAGKTRLTTEWKPESQVPQYVKNELSKPH
PNYILAFLNVVQQLKIQRRTGYLDLGIKECESISDHMYRLSIITMLIKDSRVNRDKCV
RIALVHDIAESLVGDITPVDPIGKEEKHRREWETIKYLCNALIKPYNEIAAKEIMDDW
LAYENVTSLEARYVKDIDKYEMLVQCFEYEREYKGTKNFDDFFGAVASIKTDEVKGWT
SDLVVQRQKYFADLTQSITK"
gene complement(705447..706793)
/gene="ALG7"
/locus_tag="YBR243C"
/gene_synonym="TUR1"
/db_xref="GeneID:852545"
mRNA complement(705447..706793)
/gene="ALG7"
/locus_tag="YBR243C"
/gene_synonym="TUR1"
/product="UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase"
/transcript_id="NM_001178591.3"
/db_xref="GI:398365702"
/db_xref="GeneID:852545"
CDS complement(705447..706793)
/gene="ALG7"
/locus_tag="YBR243C"
/gene_synonym="TUR1"
/EC_number="2.7.8.15"
/note="UDP-N-acetyl-glucosamine-1-P transferase, transfers
Glc-Nac-P from UDP-GlcNac to Dol-P in the ER in the first
step of the dolichol pathway of protein asparagine-linked
glycosylation; inhibited by tunicamycin"
/codon_start=1
/product="UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase"
/protein_id="NP_009802.3"
/db_xref="GI:398365703"
/db_xref="SGD:S000000447"
/db_xref="GeneID:852545"
/translation="MLRLFSLALITCLIYYSKNQGPSALVAAVGFGIAGYLATDMLIP
RVGKSFIKIGLFGKDLSKPGRPVLPETIGAIPAAVYLFVMFIYIPFIFYKYMVITTSG
GGHRDVSVVEDNGMNSNIFPHDKLSEYLSAILCLESTVLLGIADDLFDLRWRHKFFLP
AIAAIPLLMVYYVDFGVTHVLIPGFMERWLKKTSVDLGLWYYVYMASMAIFCPNSINI
LAGVNGLEVGQCIVLAILALLNDLLYFSMGPLATRDSHRFSAVLIIPFLGVSLALWKW
NRWPATVFVGDTYCYFAGMVFAVVGILGHFSKTMLLLFIPQIVNFIYSCPQLFKLVPC
PRHRLPKFNEKDGLMYPSRANLKEEPPKSIFKPILKLLYCLHLIDLEFDENNEIISTS
NMTLINLTLVWFGPMREDKLCNTILKLQFCIGILALLGRHAIGAIIFGHDNLWTVR"
gene 707528..708016
/gene="GPX2"
/locus_tag="YBR244W"
/gene_synonym="AMI1"
/db_xref="GeneID:852546"
mRNA 707528..708016
/gene="GPX2"
/locus_tag="YBR244W"
/gene_synonym="AMI1"
/product="glutathione peroxidase GPX2"
/transcript_id="NM_001178592.3"
/db_xref="GI:398365706"
/db_xref="GeneID:852546"
CDS 707528..708016
/gene="GPX2"
/locus_tag="YBR244W"
/gene_synonym="AMI1"
/EC_number="1.11.1.9"
/note="Phospholipid hydroperoxide glutathione peroxidase;
protects cells from phospholipid hydroperoxides and
nonphospholipid peroxides during oxidative stress; induced
by glucose starvation; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="glutathione peroxidase GPX2"
/protein_id="NP_009803.3"
/db_xref="GI:398365707"
/db_xref="SGD:S000000448"
/db_xref="GeneID:852546"
/translation="MTTSFYDLECKDKKGESFKFDQLKGKVVLIVNVASKCGFTPQYK
ELEELYKKYQDKGFVILGFPCNQFGKQEPGSDEQITEFCQLNYGVTFPIMKKIDVNGS
NADSVYNYLKSQKAGLLGFKGIKWNFEKFLVDSNGKVVQRFSSLTKPSSLDQEIQSLL
SK"
gene complement(708150..711539)
/gene="ISW1"
/locus_tag="YBR245C"
/gene_synonym="SGN2"
/db_xref="GeneID:852547"
mRNA complement(708150..711539)
/gene="ISW1"
/locus_tag="YBR245C"
/gene_synonym="SGN2"
/product="chromatin-remodeling ATPase ISW1"
/transcript_id="NM_001178593.1"
/db_xref="GI:296142909"
/db_xref="GeneID:852547"
CDS complement(708150..711539)
/gene="ISW1"
/locus_tag="YBR245C"
/gene_synonym="SGN2"
/EC_number="3.6.1.-"
/note="ATPase subunit of imitation-switch (ISWI) class
chromatin remodelers; ATPase; forms a complex with Ioc3p
(Isw1a), and a complex with Ioc2p and Ioc4p (Isw1b); Isw1a
and Isw1b have partially overlapping and distinct roles,
Isw1a involved in repression of transcription initiation
and Isw1b involved in regulation of transcription
elongation; Isw1b recruited to open reading frames by
H3K36 methylation and acts with Chd1p to prevent
trans-histone exchange over coding regions"
/codon_start=1
/product="chromatin-remodeling ATPase ISW1"
/protein_id="NP_009804.1"
/db_xref="GI:6319722"
/db_xref="SGD:S000000449"
/db_xref="GeneID:852547"
/translation="MAYMLAIANFHFFKFYTRMRKKHENNSCNEKDKDENLFKIILAI
FLQEKKKYDCISSGSIMTASEEYLENLKPFQVGLPPHDPESNKKRYLLKDANGKKFDL
EGTTKRFEHLLSLSGLFKHFIESKAAKDPKFRQVLDVLEENKANGKGKGKHQDVRRRK
TEHEEDAELLKEEDSDDDESIEFQFRESPAYVNGQLRPYQIQGVNWLVSLHKNKIAGI
LADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFIL
QGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEES
MLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEE
DQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDLD
AVNGSNGSKESKTRLLNIMMQLRKCCNHPYLFDGAEPGPPYTTDEHLVYNAAKLQVLD
KLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAHEDRIQAIDDYNA
PDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVF
RLVTDNSVEEKILERATQKLRLDQLVIQQNRTSLKKKENKADSKDALLSMIQHGAADV
FKSGTSTGSAGTPEPGSGEKGDDIDLDELLLKSENKTKSLNAKYETLGLDDLQKFNQD
SAYEWNGQDFKKKIQRDIISPLLLNPTKRERKENYSIDNYYKDVLNTGRSSTPSHPRM
PKPHVFHSHQLQPPQLKVLYEKERMWTAKKTGYVPTMDDVKAAYGDISDEEEKKQKLE
LLKLSVNNSQPLTEEEEKMKADWESEGFTNWNKLEFRKFITVSGKYGRNSIQAIAREL
APGKTLEEVRAYAKAFWSNIERIEDYEKYLKIIENEEEKIKRVKMQQEALRRKLSEYK
NPFFDLKLKHPPSSNNKRTYSEEEDRFILLMLFKYGLDRDDVYELVRDEIRDCPLFEL
DFYFRSRTPVELARRGNTLLQCLEKEFNAGIVLDDATKDRMKKEDENGKRIREEFADQ
TANEKENVDGVESKKAKIEDTSNVGTEQLVAEKIPENETTH"
gene 711591..712754
/gene="RRT2"
/locus_tag="YBR246W"
/gene_synonym="DPH7; ERE1"
/db_xref="GeneID:852548"
mRNA 711591..712754
/gene="RRT2"
/locus_tag="YBR246W"
/gene_synonym="DPH7; ERE1"
/product="diphthamide synthase"
/transcript_id="NM_001178594.1"
/db_xref="GI:296142910"
/db_xref="GeneID:852548"
CDS 711591..712754
/gene="RRT2"
/locus_tag="YBR246W"
/gene_synonym="DPH7; ERE1"
/note="Protein required for last step of diphthamide
biosynthesis; deletion leads to accumulation of diphthine,
which is the enzymatic product of the second step of the
biosynthesis; WD40 domain-containing protein involved in
endosomal recycling; forms a complex with Rtt10p that
functions in the retromer-mediated pathway for recycling
internalized cell-surface proteins; non-essential gene
identified in a screen for mutants with increased levels
of rDNA transcription"
/codon_start=1
/product="diphthamide synthase"
/protein_id="NP_009805.1"
/db_xref="GI:6319723"
/db_xref="SGD:S000000450"
/db_xref="GeneID:852548"
/translation="MDSIQESDVLNAVKTKLPPCCLRIFRNKIILVGTYDLDKSTGYR
SGSLDVFTMDLKLLCSNNTYGAILDLKLSPFDDTLICTAHSTGNIMLWRIRCTDKDDF
QSNELDIHAIANLQLFEKDVLIASCHFSPLDCKKLLVTNTAGEAATIDIRTLSVQFTA
SAIAQAYSKLDKIDYEVQGATEKVIHVESGQFLKPHELECWTAEFGSLQPFQDVVFTG
GDDSRIMAHDLRSKEFIWSNNRIHDAGVVSIKCSQPNFRNNKPTSIITGSYDDNIRSL
DLRMMGESIFPGANVPTVNKLACDLGGGVWRFVESPIDQEQSHHNGSDRLLVCCMYNG
AKVVTMNDNSDEYFQIQHYLKKGHDSMCYGGDWSNSLIATCSFYDNSLQTWIV"
gene complement(713004..714455)
/gene="ENP1"
/locus_tag="YBR247C"
/gene_synonym="MEG1"
/db_xref="GeneID:852549"
mRNA complement(713004..714455)
/gene="ENP1"
/locus_tag="YBR247C"
/gene_synonym="MEG1"
/product="Enp1p"
/transcript_id="NM_001178595.3"
/db_xref="GI:398365714"
/db_xref="GeneID:852549"
CDS complement(713004..714455)
/gene="ENP1"
/locus_tag="YBR247C"
/gene_synonym="MEG1"
/note="Protein associated with U3 and U14 snoRNAs,
required for pre-rRNA processing and 40S ribosomal subunit
synthesis; localized in the nucleus and concentrated in
the nucleolus"
/codon_start=1
/product="Enp1p"
/protein_id="NP_009806.3"
/db_xref="GI:398365715"
/db_xref="SGD:S000000451"
/db_xref="GeneID:852549"
/translation="MARASSTKARKQRHDPLLKDLDAAQGTLKKINKKKLAQNDAANH
DAANEEDGYIDSKASRKILQLAKEQQDEIEGEELAESERNKQFEARFTTMSYDDEDED
EDEDEEAFGEDISDFEPEGDYKEEEEIVEIDEEDAAMFEQYFKKSDDFNSLSGSYNLA
DKIMASIREKESQVEDMQDDEPLANEQNTSRGNISSGLKSGEGVALPEKVIKAYTTVG
SILKTWTHGKLPKLFKVIPSLRNWQDVIYVTNPEEWSPHVVYEATKLFVSNLTAKESQ
KFINLILLERFRDNIETSEDHSLNYHIYRAVKKSLYKPSAFFKGFLFPLVETGCNVRE
ATIAGSVLAKVSVPALHSSAALSYLLRLPFSPPTTVFIKILLDKKYALPYQTVDDCVY
YFMRFRILDDGSNGEDATRVLPVIWHKAFLTFAQRYKNDITQDQRDFLLETVRQRGHK
DIGPEIRRELLAGASREFVDPQEANDDLMIDVN"
gene complement(714807..716465)
/gene="HIS7"
/locus_tag="YBR248C"
/db_xref="GeneID:852550"
mRNA complement(714807..716465)
/gene="HIS7"
/locus_tag="YBR248C"
/product="imidazoleglycerol-phosphate synthase"
/transcript_id="NM_001178596.3"
/db_xref="GI:398365720"
/db_xref="GeneID:852550"
CDS complement(714807..716465)
/gene="HIS7"
/locus_tag="YBR248C"
/EC_number="4.1.3.-"
/EC_number="2.4.2.-"
/note="Imidazole glycerol phosphate synthase (glutamine
amidotransferase:cyclase), catalyzes the fifth step of
histidine biosynthesis and also produces
5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine
precursor"
/codon_start=1
/product="imidazoleglycerol-phosphate synthase"
/protein_id="NP_009807.3"
/db_xref="GI:398365721"
/db_xref="SGD:S000000452"
/db_xref="GeneID:852550"
/translation="MPVVHVIDVESGNLQSLTNAIEHLGYEVQLVKSPKDFNISGTSR
LILPGVGNYGHFVDNLFNRGFEKPIREYIESGKPIMGICVGLQALFAGSVESPKSTGL
NYIDFKLSRFDDSEKPVPEIGWNSCIPSENLFFGLDPYKRYYFVHSFAAILNSEKKKN
LENDGWKIAKAKYGSEEFIAAVNKNNIFATQFHPEKSGKAGLNVIENFLKQQSPPIPN
YSAEEKELLMNDYSNYGLTRRIIACLDVRTNDQGDLVVTKGDQYDVREKSDGKGVRNL
GKPVQLAQKYYQQGADEVTFLNITSFRDCPLKDTPMLEVLKQAAKTVFVPLTVGGGIK
DIVDVDGTKIPALEVASLYFRSGADKVSIGTDAVYAAEKYYELGNRGDGTSPIETISK
AYGAQAVVISVDPKRVYVNSQADTKNKVFETEYPGPNGEKYCWYQCTIKGGRESRDLG
VWELTRACEALGAGEILLNCIDKDGSNSGYDLELIEHVKDAVKIPVIASSGAGVPEHF
EEAFLKTRADACLGAGMFHRGEFTVNDVKEYLLEHGLKVRMDEE"
gene complement(716882..717994)
/gene="ARO4"
/locus_tag="YBR249C"
/db_xref="GeneID:852551"
mRNA complement(716882..717994)
/gene="ARO4"
/locus_tag="YBR249C"
/product="3-deoxy-7-phosphoheptulonate synthase ARO4"
/transcript_id="NM_001178597.1"
/db_xref="GI:296142913"
/db_xref="GeneID:852551"
CDS complement(716882..717994)
/gene="ARO4"
/locus_tag="YBR249C"
/EC_number="2.5.1.54"
/note="3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP)
synthase; catalyzes the first step in aromatic amino acid
biosynthesis and is feedback-inhibited by tyrosine or high
concentrations of phenylalanine or tryptophan; relative
distribution to the nucleus increases upon DNA replication
stress"
/codon_start=1
/product="3-deoxy-7-phosphoheptulonate synthase ARO4"
/protein_id="NP_009808.1"
/db_xref="GI:6319726"
/db_xref="SGD:S000000453"
/db_xref="GeneID:852551"
/translation="MSESPMFAANGMPKVNQGAEEDVRILGYDPLASPALLQVQIPAT
PTSLETAKRGRREAIDIITGKDDRVLVIVGPCSIHDLEAAQEYALRLKKLSDELKGDL
SIIMRAYLEKPRTTVGWKGLINDPDVNNTFNINKGLQSARQLFVNLTNIGLPIGSEML
DTISPQYLADLVSFGAIGARTTESQLHRELASGLSFPVGFKNGTDGTLNVAVDACQAA
AHSHHFMGVTKHGVAAITTTKGNEHCFVILRGGKKGTNYDAKSVAEAKAQLPAGSNGL
MIDYSHGNSNKDFRNQPKVNDVVCEQIANGENAITGVMIESNINEGNQGIPAEGKAGL
KYGVSITDACIGWETTEDVLRKLAAAVRQRREVNKK"
gene 719033..720604
/gene="SPO23"
/locus_tag="YBR250W"
/db_xref="GeneID:852552"
mRNA 719033..720604
/gene="SPO23"
/locus_tag="YBR250W"
/product="Spo23p"
/transcript_id="NM_001178598.1"
/db_xref="GI:296142914"
/db_xref="GeneID:852552"
CDS 719033..720604
/gene="SPO23"
/locus_tag="YBR250W"
/note="hypothetical protein; associates with
meiosis-specific protein Spo1p"
/codon_start=1
/product="Spo23p"
/protein_id="NP_009809.1"
/db_xref="GI:6319727"
/db_xref="SGD:S000000454"
/db_xref="GeneID:852552"
/translation="MLFSSSSSSLNSEVSQVFSENISSRSTTLTESSTQSEIRQHFGN
EDFSGELPKKLIQLKKLKNGGTTIKKAKEDLEYCYDSLRLYENPYVTSSVDKKCGYSI
ELYLDNKYKTLMFSDLQLNADYPLYYDSSLDNISTNVERERATPLQIKGKIRINIDRE
DQALLITSHSISLKCFTKEYACFVNSETSKNSYSDKIIKELNHTEFFESSTYPKQQLR
VIHHSLNDKKILLTKGTYDYPFTFTLQANTFPASFSSFFGKTHFRIESLTTIMRIPSK
PKNLLKFLKNESFTDKIILTEEIKVKRVLPSTSMLKFETFQLRSYNTASEIVVSVIGN
SKLIEIGMPFQMILSITKTDSSIELQEASLAVAQRMAIPSIDLKTKKILREPYIKKSE
YLLRTVESQSFDSDKTIFGFCFDDVVIPTYADGLPSWFKTFYCEPSSFYPNHAALKVT
HLLLFRITYSRNELVEGLEMKKNYRITVNFPILVGDSDISTSSLLPKYEKFENISDLQ
DEPPLYSMVAGENSL"
gene 721390..722313
/gene="MRPS5"
/locus_tag="YBR251W"
/db_xref="GeneID:852553"
mRNA 721390..722313
/gene="MRPS5"
/locus_tag="YBR251W"
/product="mitochondrial 37S ribosomal protein MRPS5"
/transcript_id="NM_001178599.3"
/db_xref="GI:398365730"
/db_xref="GeneID:852553"
CDS 721390..722313
/gene="MRPS5"
/locus_tag="YBR251W"
/note="Mitochondrial ribosomal protein of the small
subunit"
/codon_start=1
/product="mitochondrial 37S ribosomal protein MRPS5"
/protein_id="NP_009810.3"
/db_xref="GI:398365731"
/db_xref="SGD:S000000455"
/db_xref="GeneID:852553"
/translation="MFKRQLSTSVRYLQHYDESLLSRYYPESLLKSIKLAQQTIPEDT
KFRVSRNVEFAPPYLDDFTKIHPFWDYKPGMPHLHAQEENNNFSIFRWDQVQQPLPGE
GNILPPGVSLPNDGGRKSKSADVAAGLHKQTGVDPDYITRKLTMKPLVMKRVSNQTGK
GKIASFYALVVVGDKNGMVGLGEGKSREEMSKAIFKAHWDAVRNLKEIPRYENRTIYG
DIDFRYHGVKLHLRSAKPGFGLRVNHVIFEICECAGIKDLSGKVYKSRNDMNIAKGTI
EAFTKAQKTLDEVALGRGKKLVDVRKVYYSS"
gene 722611..723054
/gene="DUT1"
/locus_tag="YBR252W"
/db_xref="GeneID:852554"
mRNA 722611..723054
/gene="DUT1"
/locus_tag="YBR252W"
/product="bifunctional dITP/dUTP diphosphatase"
/transcript_id="NM_001178600.3"
/db_xref="GI:398365736"
/db_xref="GeneID:852554"
CDS 722611..723054
/gene="DUT1"
/locus_tag="YBR252W"
/EC_number="3.6.1.23"
/note="deoxyuridine triphosphate diphosphatase (dUTPase);
catalyzes hydrolysis of dUTP to dUMP and PPi, thereby
preventing incorporation of uracil into DNA during
replication; critical for the maintenance of genetic
stability; also has diphosphatase activity on deoxyinosine
triphosphate"
/codon_start=1
/product="bifunctional dITP/dUTP diphosphatase"
/protein_id="NP_009811.3"
/db_xref="GI:398365737"
/db_xref="SGD:S000000456"
/db_xref="GeneID:852554"
/translation="MTATSDKVLKIQLRSASATVPTKGSATAAGYDIYASQDITIPAM
GQGMVSTDISFTVPVGTYGRIAPRSGLAVKNGIQTGAGVVDRDYTGEVKVVLFNHSQR
DFAIKKGDRVAQLILEKIVDDAQIVVVDSLEESARGAGGFGSTGN"
gene 723270..723635
/gene="SRB6"
/locus_tag="YBR253W"
/gene_synonym="MED22"
/db_xref="GeneID:852555"
mRNA 723270..723635
/gene="SRB6"
/locus_tag="YBR253W"
/gene_synonym="MED22"
/product="Srb6p"
/transcript_id="NM_001178601.1"
/db_xref="GI:296142917"
/db_xref="GeneID:852555"
CDS 723270..723635
/gene="SRB6"
/locus_tag="YBR253W"
/gene_synonym="MED22"
/note="Subunit of the RNA polymerase II mediator complex;
associates with core polymerase subunits to form the RNA
polymerase II holoenzyme; essential for transcriptional
regulation"
/codon_start=1
/product="Srb6p"
/protein_id="NP_009812.1"
/db_xref="GI:6319730"
/db_xref="SGD:S000000457"
/db_xref="GeneID:852555"
/translation="MSNQALYEKLEQTRTILSVKLAELINMTTIADRNDDDEGSFAQE
NSELAVATTSVMMVNNQTMQLIKNVQDLLILTRSIKEKWLLNQIPVTEHSKVTRFDEK
QIEELLDNCIETFVAEKTT"
gene complement(723736..724263)
/gene="TRS20"
/locus_tag="YBR254C"
/db_xref="GeneID:852556"
mRNA complement(723736..724263)
/gene="TRS20"
/locus_tag="YBR254C"
/product="Trs20p"
/transcript_id="NM_001178602.1"
/db_xref="GI:296142918"
/db_xref="GeneID:852556"
CDS complement(723736..724263)
/gene="TRS20"
/locus_tag="YBR254C"
/note="One of 10 subunits of the transport protein
particle (TRAPP) complex of the cis-Golgi which mediates
vesicle docking and fusion; mutations in the human homolog
cause the spondyloepiphyseal dysplasia tarda (SEDL)
disorder"
/codon_start=1
/product="Trs20p"
/protein_id="NP_009813.1"
/db_xref="GI:6319731"
/db_xref="SGD:S000000458"
/db_xref="GeneID:852556"
/translation="MPQYFAIIGKKDNPVYEIEFTNAENPQGFPQDLKELNPFILHAS
LDIVEDLQWQINPTSQLNGNGGNGSNGGGGFLRSRAVNNTDNCYLGKVDHFYGLAITA
YISYSGMKFVMIHGNSANSSVVIDDNNMRSFYQEVHELYVKTLMNPFYKITDPIRSPA
FDSRVRTLARKHLSK"
gene 724456..726540
/gene="MTC4"
/locus_tag="YBR255W"
/db_xref="GeneID:852557"
mRNA 724456..726540
/gene="MTC4"
/locus_tag="YBR255W"
/product="Mtc4p"
/transcript_id="NM_001178603.3"
/db_xref="GI:398365744"
/db_xref="GeneID:852557"
CDS 724456..726540
/gene="MTC4"
/locus_tag="YBR255W"
/note="hypothetical protein, required for normal growth
rate at 15 degrees C; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm in a
punctate pattern; mtc4 is synthetically sick with cdc13-1"
/codon_start=1
/product="Mtc4p"
/protein_id="NP_009814.3"
/db_xref="GI:398365745"
/db_xref="SGD:S000000459"
/db_xref="GeneID:852557"
/translation="MTHTNEHDHKAEQQQNGRGDTTTETVNPQKMKLVTKLLIDNKFG
LMDDLNFSIPLTASSEGVPISAKTSELGTEYLKNQQENSVSPILPISRSTRIKADRVR
IYLDYYYNILERCISIDSSQNHHEGVEGVYNPLQVIRNRKLKKKHHELPTREFYTTKH
PIIAIKQFSKKPNKKMPWFVDINEKYMDLTWRTSHWEELVDPQGKLWFQSYSPSNESS
GSSSSRRHHGHHIHPRRHLQHHSRVRTANSVHSNTQSLTPKRVMTNEEDNNNHNNNNM
ITKIATTPEAQISRNKKSDLNLSHIHLEVPITNTVTNTSSDQGSLIIEAKGSSYGGDR
RGSSNTSGSGGKRNSKHYRSKSAGPPENEKSRMNGLEKIISKTSKGWSRSPKKNTPGL
EKQVLLNPTISNGGTSRRSSNNGESISTNSSKSSMGITFGNTETYKTPVDNGKDAIIR
QSLLSEVPVHTLRGKTSNRSLRAEGEQALESDKELPNGAGSIYEGAPREKTTSQGSEP
VGLVSDSLQVDEQLQRYWHDTRYIMSTVAMMQHRRETHDIVKRREIARRNEIEITQDA
DTNIRKTADALTQYDNELNKVLKLGNDWTSKLLNDYSIRVETLISSSDRILSDINTTL
TLKLKMFQENTERYVTVKVMRAQKMTKTIYRLLEFGIVLVLWTIWFLFSVLRSIRFTI
FLVLKIIKALLW"
gene complement(726618..727074)
/locus_tag="YBR255C-A"
/db_xref="GeneID:852558"
mRNA complement(join(726618..726917,727012..727074))
/locus_tag="YBR255C-A"
/product="hypothetical protein"
/transcript_id="NM_001184510.3"
/db_xref="GI:398365750"
/db_xref="GeneID:852558"
CDS complement(join(726618..726917,727012..727074))
/locus_tag="YBR255C-A"
/note="hypothetical protein; may interact with respiratory
chain complexes III (ubiquinol-cytochrome c reductase) or
IV (cytochrome c oxidase); identified by sequence
comparison with hemiascomycetous yeast species"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_116328.4"
/db_xref="GI:398365751"
/db_xref="SGD:S000007649"
/db_xref="GeneID:852558"
/translation="MGGNVLPIHYDPKTVKQLTKEITVASCIGAAQGALFSIASALLL
RRFSSVYRNVRTQVRVFYHCSWISMGAVFRADKQLLKFQTNYYREEQKRREKIMDEAA
ERGLFLEDESLNSSRSTT"
gene complement(727386..728102)
/gene="RIB5"
/locus_tag="YBR256C"
/db_xref="GeneID:852559"
mRNA complement(727386..728102)
/gene="RIB5"
/locus_tag="YBR256C"
/product="riboflavin synthase"
/transcript_id="NM_001178604.1"
/db_xref="GI:296142921"
/db_xref="GeneID:852559"
CDS complement(727386..728102)
/gene="RIB5"
/locus_tag="YBR256C"
/EC_number="2.5.1.9"
/note="Riboflavin synthase; catalyzes the last step of the
riboflavin biosynthesis pathway"
/codon_start=1
/product="riboflavin synthase"
/protein_id="NP_009815.1"
/db_xref="GI:6319733"
/db_xref="SGD:S000000460"
/db_xref="GeneID:852559"
/translation="MFTGIVECMGTVLENNPYDDSESGGQGVSITIGNAGSILTDCHV
GDSIAVNGVCLTVTEFNNDSFKVGISPETIKRSNVASWIQGTQVNLERAVSQDVRFGG
HYVQGHVDTVANIVSRRPEGNSIIFGFQLRDQEYFKYIVEKGFICIDGTSLTIIKVDP
LSQGGAFYISMIKHTQDNVIMPLKKIGDEVNIEVDLTGKIIEKQILLTLENQISKKDS
TLNTMISNIIEEKVRNYLNK"
gene 728885..729724
/gene="POP4"
/locus_tag="YBR257W"
/db_xref="GeneID:852560"
mRNA 728885..729724
/gene="POP4"
/locus_tag="YBR257W"
/product="Pop4p"
/transcript_id="NM_001178605.1"
/db_xref="GI:296142922"
/db_xref="GeneID:852560"
CDS 728885..729724
/gene="POP4"
/locus_tag="YBR257W"
/note="Subunit of both RNase MRP and nuclear RNase P;
RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves
tRNA precursors to generate mature 5' ends and facilitates
turnover of nuclear RNAs; binds to the RPR1 RNA subunit in
RNase P"
/codon_start=1
/product="Pop4p"
/protein_id="NP_009816.1"
/db_xref="GI:6319734"
/db_xref="SGD:S000000461"
/db_xref="GeneID:852560"
/translation="MDRTQTFIKDCLFTKCLEDPEKPFNENRFQDTLLLLPTDGGLTS
RLQRQQRKSKLNLDNLQKVSQLESADKQLEKRDYQRINKNSKIALREYINNCKKNTKK
CLKLAYENKITDKEDLLHYIEEKHPTIYESLPQYVDFVPMYKELWINYIKELLNITKN
LKTFNGSLALLKLSMADYNGALLRVTKSKNKTLIGLQGIVIWDSQKFFIMIVKGNIID
EIKCIPKKGTVFQFEIPISDDDDSALRYSILGDRFKYRSVDRAGRKFKSRRCDDMLYY
IQN"
gene complement(729734..730162)
/gene="SHG1"
/locus_tag="YBR258C"
/gene_synonym="CPS15"
/db_xref="GeneID:852561"
mRNA complement(729734..730162)
/gene="SHG1"
/locus_tag="YBR258C"
/gene_synonym="CPS15"
/product="Shg1p"
/transcript_id="NM_001178606.3"
/db_xref="GI:398365768"
/db_xref="GeneID:852561"
CDS complement(729734..730162)
/gene="SHG1"
/locus_tag="YBR258C"
/gene_synonym="CPS15"
/note="Subunit of the COMPASS (Set1C) complex, which
methylates histone H3 on lysine 4 and is required in
transcriptional silencing near telomeres"
/codon_start=1
/product="Shg1p"
/protein_id="NP_009817.3"
/db_xref="GI:398365769"
/db_xref="SGD:S000000462"
/db_xref="GeneID:852561"
/translation="MAYNQEDSKRLSDKYKKEGHFDKLKREILSNPWNNTEENSESFE
QALRKRVASTVKEMVNEDEELIFKNRGLTSALIESQLVKDNYLKLGSKMEGDNGDGEK
KFDLDVYVRSKLQDPKLLEMIKGQLQETLNSYEEEANGST"
gene 730387..732453
/locus_tag="YBR259W"
/db_xref="GeneID:852562"
mRNA 730387..732453
/locus_tag="YBR259W"
/product="hypothetical protein"
/transcript_id="NM_001178607.3"
/db_xref="GI:398365772"
/db_xref="GeneID:852562"
CDS 730387..732453
/locus_tag="YBR259W"
/note="hypothetical protein; YBR259W is not an essential
gene; forms cytoplasmic foci upon DNA replication stress"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009818.3"
/db_xref="GI:398365773"
/db_xref="SGD:S000000463"
/db_xref="GeneID:852562"
/translation="MSIDEAVARYRDVIGNLATGNLRRIVIQSEKLAQIIASSKGTVR
FHHKTRSGKTVIYKCIKKALLSSVASLSSEFSSETDVQQFLHLNYIYQSHFQALSGQI
NKYCGMKKYYELKFAAIDYLETEVQTTGLTLSRFWVASLDEFIKKERWPDNGSNFQIF
YKLMAEYSSWKWDSDDKRQLQFMYEFRMKLKECLVKFYENFDLQKSSDPLKELIIPWE
KIVYVANCIDAFTGEQVRIDGAELIWTSKNLVFSSISSAVLRLNDLQNMFSAFRPYGE
EALVQDFAHIRSLKWDSNDKVESLIRALIFNDMFPYFNKEQVDTKADGIFFLRLLRKN
FKEHINDVKDFHIQVIKYLNSQFKNNYSTLMTSSKTQDRRKSHNMPSSILDDGNKIGM
HVSPIDEYSHFIDNDEPLWRDKVYPKIYTNEQTPTPDASAIFDSHKIYAIISLLRYYL
PEKRKFFRIYYLPSIFKRILYYGAKFAQLYFMEGCLERLVIESLQILEPSLVHAINNL
IKSSIESLKNVTVTSDDKTSSGVIILSYKEFKSLSEVNKDFNEPFWPNQSIANSWPDF
ANKQLKRGQILQDAFAFHLFEIELPIIIDTTRNTHLKLVSNMCTTSILYLYNEVDSLS
LTSIQEKLAVLPTSKRNEILLYNLNRLTKLKLLLLKENEKGQKFYAFNFKYKRDGQKT
SLIRLI"
gene complement(732639..734639)
/gene="RGD1"
/locus_tag="YBR260C"
/db_xref="GeneID:852563"
mRNA complement(732639..734639)
/gene="RGD1"
/locus_tag="YBR260C"
/product="Rgd1p"
/transcript_id="NM_001178608.1"
/db_xref="GI:296142925"
/db_xref="GeneID:852563"
CDS complement(732639..734639)
/gene="RGD1"
/locus_tag="YBR260C"
/note="GTPase-activating protein (RhoGAP) for Rho3p and
Rho4p, possibly involved in control of actin cytoskeleton
organization"
/codon_start=1
/product="Rgd1p"
/protein_id="NP_009819.1"
/db_xref="GI:6319737"
/db_xref="SGD:S000000464"
/db_xref="GeneID:852563"
/translation="MEETAKKPASATVSAKSSHDGGTDDLAHLFSTPEIKKVLNSDVA
INALLSRLKQSLLTCEEFMKFIRKKYAFEEEHVQELSKQYKHFFNIQGSTNSSLKKMI
HEVLGFDGKMAQVKQSYITALQKMYSEISSLLLTMTKLRKSVKENSKRLEKDVSDAIH
SAEKAQSRYNSLCQDWDKLRMTDPTKTKLTLRGSKTTKEQEEELLRKIDNADLEYKQK
VDHSNSLRNTFITKERPRIVQELKDLILEIDTAMTIQLQKYTIWTENLVLNTGVTISP
LDSTKSMKSFAGSVSNERDLYSFLNKYNQTGKHSLLINKNLIPVSYKKHPSMNHGQKN
KSPPKFAVDPSRNSIPKRMISTHNESPFLSSSSNTAAVPNANLNSATPSLNTNKQLPP
TMASSISSTSNAAGAMSPSSSIVTSDTTSSITKTLDPGNNSPQIPEELINSLDSDRPI
SHIQTNNNMPPGVQKNFKTFGVPLESLIEFEQDMVPAIVRQCIYVIDKFGLDQEGIYR
KSANVLDVSKLKEEIDKDPANISMILPSKPHSDSDIYLVGSLLKTFFASLPDSVLPKA
LSSEIKVCLQIEDPTTRKNFMHGLIYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLR
ALCIIWGPTIAPANPDDANDVNFQIMAMEVLLEVSDQAFEPE"
gene complement(734832..735530)
/gene="TAE1"
/locus_tag="YBR261C"
/gene_synonym="NTM1"
/db_xref="GeneID:852564"
mRNA complement(734832..735530)
/gene="TAE1"
/locus_tag="YBR261C"
/gene_synonym="NTM1"
/product="Tae1p"
/transcript_id="NM_001178609.1"
/db_xref="GI:296142926"
/db_xref="GeneID:852564"
CDS complement(734832..735530)
/gene="TAE1"
/locus_tag="YBR261C"
/gene_synonym="NTM1"
/note="AdoMet-dependent proline methyltransferase;
catalyzes the dimethylation of ribosomal proteins Rpl12
and Rps25 at N-terminal proline residues; has a role in
protein synthesis; fusion protein localizes to the
cytoplasm"
/codon_start=1
/product="Tae1p"
/protein_id="NP_009820.1"
/db_xref="GI:6319738"
/db_xref="SGD:S000000465"
/db_xref="GeneID:852564"
/translation="MDVPADSHIKYEDAIDYWTDVDATVDGVLGGYGEGTVVPTMDVL
GSNNFLRKLKSRMLPQENNVKYAVDIGAGIGRVSKTMLHKHAAKIDLVEPVKPFIEQM
HVELAELKDKGQIGQIYEVGMQDWTPDAGKYWLIWCQWCVGHLPDAELVAFLKRCIVG
LQPNGTIVVKENNTPTDTDDFDETDSSVTRSDAKFRQIFEEAGLKLIASERQRGLPRE
LYPVRMYALKPMPN"
gene complement(735720..736040)
/gene="AIM5"
/locus_tag="YBR262C"
/gene_synonym="FMP51; MCS12"
/db_xref="GeneID:852566"
mRNA complement(735720..736040)
/gene="AIM5"
/locus_tag="YBR262C"
/gene_synonym="FMP51; MCS12"
/product="Aim5p"
/transcript_id="NM_001178610.3"
/db_xref="GI:398365786"
/db_xref="GeneID:852566"
CDS complement(735720..736040)
/gene="AIM5"
/locus_tag="YBR262C"
/gene_synonym="FMP51; MCS12"
/note="Mitochondrial inner membrane protein; subunit of
the mitochondrial inner membrane organizing system (MitOS,
MICOS, or MINOS), a scaffold-like structure on the
intermembrane space side of the inner membrane which has a
role in the maintenance of crista junctions and inner
membrane architecture"
/codon_start=1
/product="Aim5p"
/protein_id="NP_009821.3"
/db_xref="GI:398365787"
/db_xref="SGD:S000000466"
/db_xref="GeneID:852566"
/translation="MSKLGPLARSVKWTLSVGVIGSVFYLYRYSNNGYFYDHDATWLK
QDHQVQDLVDRKEVVPGETRNRKLVVTDDGTAWSRTMGESIKDIWNEQIRNSVDWIYS
WGKN"
gene 736264..737736
/gene="SHM1"
/locus_tag="YBR263W"
/gene_synonym="SHMT1; TMP3"
/db_xref="GeneID:852565"
mRNA 736264..737736
/gene="SHM1"
/locus_tag="YBR263W"
/gene_synonym="SHMT1; TMP3"
/product="glycine hydroxymethyltransferase SHM1"
/transcript_id="NM_001178611.3"
/db_xref="GI:398365792"
/db_xref="GeneID:852565"
CDS 736264..737736
/gene="SHM1"
/locus_tag="YBR263W"
/gene_synonym="SHMT1; TMP3"
/EC_number="2.1.2.1"
/note="Mitochondrial serine hydroxymethyltransferase,
converts serine to glycine plus 5,10
methylenetetrahydrofolate; involved in generating
precursors for purine, pyrimidine, amino acid, and lipid
biosynthesis; reverse reaction generates serine"
/codon_start=1
/product="glycine hydroxymethyltransferase SHM1"
/protein_id="NP_009822.4"
/db_xref="GI:398365793"
/db_xref="SGD:S000000467"
/db_xref="GeneID:852565"
/translation="MFPRASALAKCMATVHRRGLLTSGAQSLVSKPVSEGDPEMFDIL
QQERHRQKHSITLIPSENFTSKAVMDLLGSELQNKYSEGYPGERYYGGNEIIDKSESL
CQARALELYGLDPAKWGVNVQPLSGAPANLYVYSAIMNVGERLMGLDLPDGGHLSHGY
QLKSGTPISFISKYFQSMPYHVDHTTGLIDYDNLQVLAKAFRPKVIVAGTSAYSRLID
YARFKEISQGCGAYLMSDMAHISGLVAANVVPSPFEHSDIVTTTTHKSLRGPRGAMIF
FRKGIKSVTKKGKEIPYELEKKINFSVFPGHQGGPHNHTIGAMAVALKQAMSPEFKEY
QQKIVDNSKWFAQELTKMGYKLVSGGTDNHLIVIDLSGTQVDGARVETILSALNIAAN
KNTIPGDKSALFPSGLRIGTPAMTTRGFGREEFSQVAKYIDSAVKLAENLKTLEPTTK
LDARSRLNEFKKLCNESSEVAALSGEISKWVGQYPVPGDI"
gene complement(737770..738369)
/gene="YPT10"
/locus_tag="YBR264C"
/db_xref="GeneID:852567"
mRNA complement(737770..738369)
/gene="YPT10"
/locus_tag="YBR264C"
/product="Ypt10p"
/transcript_id="NM_001178612.1"
/db_xref="GI:296142929"
/db_xref="GeneID:852567"
CDS complement(737770..738369)
/gene="YPT10"
/locus_tag="YBR264C"
/note="Rab family GTP-binding protein that contains the
PEST signal sequence specific for proteolytic enzymes; may
be involved in vesicular transport; overexpression leads
to accumulation of Golgi-like cisternae with budding
vesicles"
/codon_start=1
/product="Ypt10p"
/protein_id="NP_009823.2"
/db_xref="GI:37362623"
/db_xref="SGD:S000000468"
/db_xref="GeneID:852567"
/translation="MEATIKVVLLGDSSVGKTSIVTRLKSGKFLAKHAATIGAAFITK
TIEVPSNDSSTEKRIHMEIWDTAGQERYKSLVPMYYRDANIALIVFELGDVSSLQCAK
TWFQDLQDRAQGTQVIIVGNKYDLVCEEHSGEVTIPAELQGLPYVAVSAKTGYNFDTL
NKIIISLVPESQFKTLSKNNEQGNILEINKKKSGSGCIC"
gene 738582..739544
/gene="TSC10"
/locus_tag="YBR265W"
/db_xref="GeneID:852568"
mRNA 738582..739544
/gene="TSC10"
/locus_tag="YBR265W"
/product="3-dehydrosphinganine reductase"
/transcript_id="NM_001178613.2"
/db_xref="GI:330443466"
/db_xref="GeneID:852568"
CDS 738582..739544
/gene="TSC10"
/locus_tag="YBR265W"
/EC_number="1.1.1.102"
/note="3-ketosphinganine reductase, catalyzes the second
step in phytosphingosine synthesis, essential for growth
in the absence of exogenous dihydrosphingosine or
phytosphingosine, member of short chain
dehydrogenase/reductase protein family"
/codon_start=1
/product="3-dehydrosphinganine reductase"
/protein_id="NP_009824.2"
/db_xref="GI:330443467"
/db_xref="SGD:S000000469"
/db_xref="GeneID:852568"
/translation="MKFTLEDQVVLITGGSQGLGKEFAKKYYNEAENTKIIIVSRSEA
RLLDTCNEIRIEAHLRRETTDEGQVQHKLAAPLDLEQRLFYYPCDLSCYESVECLFNA
LRDLDLLPTQTLCCAGGAVPKLFRGLSGHELNLGMDINYKTTLNVAHQIALAEQTKEH
HLIIFSSATALYPFVGYSQYAPAKAAIKSLVAILRQELTNFRISCVYPGNFESEGFTV
EQLTKPEITKLIEGPSDAIPCKQACDIIAKSLARGDDDVFTDFVGWMIMGMDLGLTAK
KSRFVPLQWIFGVLSNILVVPFYMVGCSWYIRKWFRENDGKKAN"
gene 739841..741022
/gene="REI1"
/locus_tag="YBR267W"
/db_xref="GeneID:852569"
mRNA 739841..741022
/gene="REI1"
/locus_tag="YBR267W"
/product="Rei1p"
/transcript_id="NM_001178615.4"
/db_xref="GI:398365806"
/db_xref="GeneID:852569"
CDS 739841..741022
/gene="REI1"
/locus_tag="YBR267W"
/note="Cytoplasmic pre-60S factor; required for the
correct recycling of shuttling factors Alb1, Arx1 and Tif6
at the end of the ribosomal large subunit biogenesis;
involved in bud growth in the mitotic signaling network"
/codon_start=1
/product="Rei1p"
/protein_id="NP_009825.4"
/db_xref="GI:398365807"
/db_xref="SGD:S000000471"
/db_xref="GeneID:852569"
/translation="MSSSGVYTCNSCVLTFDSSDEQRAHMKSDWHRYNLKRRVAQLPP
ISFETFDSKVSAAAASTSKSAEKEKPVTKKELKRREKQALLEKKKKLLEIARANMLEN
MQKSQEGNTPDLSKLSLQENEENKEKEEPKKEEPEQLTEEEMAERVMQEKLRNRVDIP
LEQCLFCEHNKHFKDVEENLEHMFRTHGFYIPEQKYLVDKIGLVKYMSEKIGLGNICI
VCNYQGRTLTAVRQHMLAKRHCKIPYESEDERLEISEFYDFTSSYANFNSNTTPDNED
DWEDVGSDEAGSDDEDLPQEYLYNDGIELHLPTGIKVGHRSLQRYYKQDLKPEVILTE
GQGTLVAAETRSFLPAFDKKGVQTQQRVWQTERFDKKRLDKRSAKFVNNQPHYRDQLL
Q"
gene 741299..741616
/gene="MRPL37"
/locus_tag="YBR268W"
/db_xref="GeneID:852571"
mRNA 741299..741616
/gene="MRPL37"
/locus_tag="YBR268W"
/product="mitochondrial 54S ribosomal protein YmL37"
/transcript_id="NM_001178616.3"
/db_xref="GI:398365810"
/db_xref="GeneID:852571"
CDS 741299..741616
/gene="MRPL37"
/locus_tag="YBR268W"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL37"
/protein_id="NP_009827.3"
/db_xref="GI:398365811"
/db_xref="SGD:S000000472"
/db_xref="GeneID:852571"
/translation="MLARSLGYRLISTSRILYNKPTVKSVVSSCPAGTSLNLNIWKSG
KDAVALEDKEYPNWLWSVLDSDHVVEHAAEDPEGQALLKRRKNIRKANRQRIKQNNFL
SQL"
rep_origin 741558..741847
/note="ARS224;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118353"
gene complement(742160..742576)
/gene="FMP21"
/locus_tag="YBR269C"
/db_xref="GeneID:852572"
mRNA complement(742160..742576)
/gene="FMP21"
/locus_tag="YBR269C"
/product="Fmp21p"
/transcript_id="NM_001178617.1"
/db_xref="GI:296142933"
/db_xref="GeneID:852572"
CDS complement(742160..742576)
/gene="FMP21"
/locus_tag="YBR269C"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="Fmp21p"
/protein_id="NP_009828.2"
/db_xref="GI:41629680"
/db_xref="SGD:S000000473"
/db_xref="GeneID:852572"
/translation="MLCAIKSTGYRYPRTGALNLLRGRPFNMATRKITTERIPGPPKL
PREEQEEFERLQRIATSQEAIDQYNAQATGDRTKESLNSPLLTKNDIGSFSPEFSKTI
PEFEGDVNPKTGEVGGPKQDPLRHGDYSFNGRVTDF"
gene complement(742761..744398)
/gene="BIT2"
/locus_tag="YBR270C"
/db_xref="GeneID:852573"
mRNA complement(742761..744398)
/gene="BIT2"
/locus_tag="YBR270C"
/product="Bit2p"
/transcript_id="NM_001178618.2"
/db_xref="GI:330443470"
/db_xref="GeneID:852573"
CDS complement(742761..744398)
/gene="BIT2"
/locus_tag="YBR270C"
/note="Subunit of TORC2, a membrane-associated complex
that regulates actin cytoskeletal dynamics during
polarized growth and cell wall integrity; interacts with
Slm1p and Slm2p, homologous PH domain-containing TORC2
substrates; similar to Bit61p"
/codon_start=1
/product="Bit2p"
/protein_id="NP_009829.2"
/db_xref="GI:330443471"
/db_xref="SGD:S000000474"
/db_xref="GeneID:852573"
/translation="MATDLNRKRSATSGSLSVTNPNIKATNRKPARVYSVSSDIVPQA
LTHPDEDVHLKTSKSPHDAAPRWSQVGFQSIFHDGSNARRSTDSIEEEYSQGTENNDG
HSEIGSSSSNRMEGNTTSNDSLFSSNSRGNKRRLSIFTNSKDNMRNRSRSGSKNYGTV
ITGTSSNNISRSGSKLFHTKSNMSVNSLQSSLSTGHSHSNKGSNVFSKMAKKLLPYKP
HNSIGKDDVEPVVPSPFSKFLHSSYGKHRSPVQFIHTSTGGLIDSGKSVYSFNPSINN
NPNDTALSLIQDDAFDATNVSLLHDLLKNLPSLIANYKSFTVQELFVLEGNIWGIYCS
IVVELFKNKRVWQLPAKIEDIDRLLEFYITLKTQTKAAVTHSRFLAEIEEFITTSLYI
LENQIVFNYANEDTVNTALKRVGIIWKVFYQQVYYDMMAVLLPFEKSFQKNSNYWLDG
YLSEPSRYAPSIDVLLLKCFRDSIILPYYESFLHTNDGASKSFQRYIFSEEEQNGVTE
EDKLTLLQCFGILNTIKGNSRNQRIIGELLEGIRMSI"
gene 744852..746111
/gene="EFM2"
/locus_tag="YBR271W"
/db_xref="GeneID:852574"
mRNA 744852..746111
/gene="EFM2"
/locus_tag="YBR271W"
/product="Efm2p"
/transcript_id="NM_001178619.3"
/db_xref="GI:398365820"
/db_xref="GeneID:852574"
CDS 744852..746111
/gene="EFM2"
/locus_tag="YBR271W"
/note="S-adenosylmethionine-dependent methyltransferase;
methylates translation elongation factors EF2 (Eft1p and
Eft2p) and EF3A (Yef3p); belongs to the seven beta-strand
family; green fluorescent protein (GFP)-fusion protein
localizes to the cytoplasm; predicted to be involved in
ribosome biogenesis"
/codon_start=1
/product="Efm2p"
/protein_id="NP_009830.3"
/db_xref="GI:398365821"
/db_xref="SGD:S000000475"
/db_xref="GeneID:852574"
/translation="MFDPLDLYTPDDIQVEALQFNLAEREPKDPCSPQRDEILTAVDE
EESDDDDTIIDNLDLPSVKYAPPEVILCILILLKPDRQVNFNQETGKNKSVLEVCKSH
GLEPDLLKRLLTWYTEEWPNKRLNSLEKICNKIPMLRFTVSKELLLGYYTSVLKKYNN
SCGLNEEIIQELLKELSSRISENCGRTAQPSIVRYFELRNLSTSIPLHEPSLTADNLG
WKTWGSSLILSQLVVDHLDYLHTTNVNMLANSDIKQIKVLELGAGTGLVGLSWALKWK
ELYGTENIEIFVTDLPEIVTNLKKNVSLNNLGDFVQAEILDWTNPHDFIDKFGHENEF
DVILIADPIYSPQHPEWVVNMISKFLAASGTCHLEIPLRAKYAKEREVLKLLLKESDL
KVVEERHSEGVDDWGAVKYLYRQIVRN"
gene complement(746361..747803)
/gene="HSM3"
/locus_tag="YBR272C"
/db_xref="GeneID:852575"
mRNA complement(746361..747803)
/gene="HSM3"
/locus_tag="YBR272C"
/product="Hsm3p"
/transcript_id="NM_001178620.3"
/db_xref="GI:398365824"
/db_xref="GeneID:852575"
CDS complement(746361..747803)
/gene="HSM3"
/locus_tag="YBR272C"
/note="Proteasome-interacting protein involved in the
assembly of the base subcomplex of the 19S proteasomal
regulatory particle (RP); involved in DNA mismatch repair
during slow growth; weak similarity to Msh1p; related to
human 19S subunit S5b; structural study suggests Hsm3p is
a scaffold protein for Rpt1p-Rpt2p complex formation"
/codon_start=1
/product="Hsm3p"
/protein_id="NP_009831.3"
/db_xref="GI:398365825"
/db_xref="SGD:S000000476"
/db_xref="GeneID:852575"
/translation="MSEKETNYVENLLTQLENELNEDNLPEDINTLLRKCSLNLVTVV
SLPDMDVKPLLATIKRFLTSNVSYDSLNYDYLLDVVDKLVPMADFDDVLEVYSAEDLV
KALRSEIDPLKVAACRVIENSQPKGLFATSNIIDILLDILFDEKVENDKLITAIEKAL
ERLSTDELIRRRLFDNNLPYLVSVKGRMETVSFVRLIDFLTIEFQFISGPEFKDIIFC
FTKEEILKSVEDILVFIELVNYYTKFLLEIRNQDKYWALRHVKKILPVFAQLFEDTEN
YPDVRAFSTNCLLQLFAEVSRIEEDEYSLFKTMDKDSLKIGSEAKLITEWLELINPQY
LVKYHKDVVENYFHVSGYSIGMLRNLSADEECFNAIRNKFSAEIVLRLPYLEQMQVVE
TLTRYEYTSKFLLNEMPKVMGSLIGDGSAGAIIDLETVHYRNSALRNLLDKGEEKLSV
WYEPLLREYSKAVNGKNYSTGSETKIADCR"
gene complement(748061..749371)
/gene="UBX7"
/locus_tag="YBR273C"
/gene_synonym="CUI3"
/db_xref="GeneID:852576"
mRNA complement(748061..749371)
/gene="UBX7"
/locus_tag="YBR273C"
/gene_synonym="CUI3"
/product="Ubx7p"
/transcript_id="NM_001178621.1"
/db_xref="GI:296142937"
/db_xref="GeneID:852576"
CDS complement(748061..749371)
/gene="UBX7"
/locus_tag="YBR273C"
/gene_synonym="CUI3"
/note="UBX (ubiquitin regulatory X) domain-containing
protein that interacts with Cdc48p"
/codon_start=1
/product="Ubx7p"
/protein_id="NP_009832.1"
/db_xref="GI:6319750"
/db_xref="SGD:S000000477"
/db_xref="GeneID:852576"
/translation="MLEALFRDSVEEAINDSIKEGVVLAVYNTARDDQWLKSWFKGDD
VSLDTLAEHSIWLRLVKDTEQFQLFEQVFPNVVVPSIYLIRAGKIELIIQGEDDRHWE
KLLACIGIKDKKAGESSSRETNPGLAREEKSSRDVHRKNARERIAETTLEIQRREQLK
QRKLAEEERERIIRLVRADRAERKALDETHHRTLDDDKPLDVHDYIKDAQKLHSSKCV
LQIRMTDGKTLKHEFNSSETLNDVRKWVDVNRTDGDCPYSFHRGIPRVTFKDSDELKT
LETLELTPRSALLLKPLETQNSGLSVTGMEGPSLLGRLYKGFSTWWHNDKDPEVTSQR
EETSKPNRHEVRSSTPLSGAASSSCFQYNNVREPVQSSAHASPMLTPSGTRYPSETNL
TTSRSVSPNVFQFVNNDHQEDPEDPTTFNGNNVHLEKKKDEDKK"
gene 749594..751177
/gene="CHK1"
/locus_tag="YBR274W"
/db_xref="GeneID:852577"
mRNA 749594..751177
/gene="CHK1"
/locus_tag="YBR274W"
/product="Chk1p"
/transcript_id="NM_001178622.1"
/db_xref="GI:296142938"
/db_xref="GeneID:852577"
CDS 749594..751177
/gene="CHK1"
/locus_tag="YBR274W"
/EC_number="2.7.11.1"
/note="Serine/threonine kinase and DNA damage checkpoint
effector, mediates cell cycle arrest via phosphorylation
of Pds1p; phosphorylated by checkpoint signal transducer
Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint
kinase"
/codon_start=1
/product="Chk1p"
/protein_id="NP_009833.1"
/db_xref="GI:6319751"
/db_xref="SGD:S000000478"
/db_xref="GeneID:852577"
/translation="MSLSQVSPLPHIKDVVLGDTVGQGAFACVKNAHLQMDPSIILAV
KFIHVPTCKKMGLSDKDITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGD
LFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLAD
FGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTG
QTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKRVTLKALK
LHPWVLRRASFSGDDGLCNDPELLAKKLFSHLKVSLSNENYLKFTQDTNSNNRYISTQ
PIGNELAELEHDSMHFQTVSNTQRAFTSYDSNTNYNSGTGMTQEAKWTQFISYDIAAL
QFHSDENDCNELVKRHLQFNPNKLTKFYTLQPMDVLLPILEKALNLSQIRVKPDLFAN
FERLCELLGYDNVFPLIINIKTKSNGGYQLCGSISIIKIEEELKSVGFERKTGDPLEW
RRLFKKISTICRDIILIPN"
gene complement(751356..757106)
/gene="RIF1"
/locus_tag="YBR275C"
/db_xref="GeneID:852578"
mRNA complement(751356..757106)
/gene="RIF1"
/locus_tag="YBR275C"
/product="Rif1p"
/transcript_id="NM_001178623.4"
/db_xref="GI:398365840"
/db_xref="GeneID:852578"
CDS complement(751356..757106)
/gene="RIF1"
/locus_tag="YBR275C"
/note="Protein that binds to the Rap1p C-terminus and acts
synergistically with Rif2p to help control telomere length
and establish telomeric silencing; deletion results in
telomere elongation"
/codon_start=1
/product="Rif1p"
/protein_id="NP_009834.4"
/db_xref="GI:398365841"
/db_xref="SGD:S000000479"
/db_xref="GeneID:852578"
/translation="MSKDFSDKKKHTIDRIDQHILRRSQHDNYSNGSSPWMKTNLPPP
SPQAHMHIQSDLSPTPKRRKLASSSDCENKQFDLSAINKNLYPEDTGSRLMQSLPELS
ASNSDNVSPVTKSVAFSDRIESSPIYRIPGSSPKPSPSSKPGKSILRNRLPSVRTVSD
LSYNKLQYTQHKLHNGNIFTSPYKETRVNPRALEYWVSGEIHGLVDNESVSEFKEIIE
GGLGILRQESEDYVARRFEVYATFNNIIPILTTKNVNEVDQKFNILIVNIESIIEICI
PHLQIAQDTLLSSSEKKNPFVIRLYVQIVRFFSAIMSNFKIVKWLTKRPDLVNKLKVI
YRWTTGALRNENSNKIIITAQVSFLRDEKFGTFFLSNEEIKPIISTFTEIMEINSHNL
IYEKLLLIRGFLSKYPKLMIETVTSWLPGEVLPRIIIGDEIYSMKILITSIVVLLELL
KKCLDFVDEHERIYQCIMLSPVCETIPEKFLSKLPLNSYDSANLDKVTIGHLLTQQIK
NYIVVKNDNKIAMDLWLSMTGLLYDSGKRVYDLTSESNKVWFDLNNLCFINNHPKTRL
MSIKVWRIITYCICTKISQKNQEGNKSLLSLLRTPFQMTLPYVNDPSAREGIIYHLLG
VVYTAFTSNKNLSTDMFELFWDHLITPIYEDYVFKYDSIHLQNVLFTVLHLLIGGKNA
DVALERKYKKHIHPMSVIASEGVKLKDISSLPPQIIKREYDKIMKVVFQAVEVAISNV
NLAHDLILTSLKHLPEDRKDQTHLESFSSLILKVTQNNKDTPIFRDFFGAVTSSFVYT
FLDLFLRKNDSSLVNFNIQISKVGISQGNMTLDLLKDVIRKARNETSEFLIIEKFLEL
DDKKTEVYAQNWVGSTLLPPNISFREFQSLANIVNKVPNENSIENFLDLCLKLSFPVN
LFTLLHVSMWSNNNFIYFIQSYVSKNENKLNVDLITLLKTSLPGNPELFSGLLPFLRR
NKFMDILEYCIHSNPNLLNSIPDLNSDLLLKLLPRSRASYFAANIKLFKCSEQLTLVR
WLLKGQQLEQLNQNFSEIENVLQNASDSELEKSEIIRELLHLAMANPIEPLFSGLLNF
CIKNNMADHLDEFCGNMTSEVLFKISPELLLKLLTYKEKPNGKLLAAVIEKIENGDDD
YILELLEKIIIQKEIQILEKLKEPLLVFFLNPVSSNMQKHKKSTNMLRELVLLYLTKP
LSRSAAKKFFSMLISILPPNPNYQTIDMVNLLIDLIKSHNRKFKDKRTYNATLKTIGK
WIQESGVVHQGDSSKEIEAIPDTKSMYIPCEGSENKLSNLQRKVDSQDIQVPATQGMK
EPPSSIQISSQISAKDSDSISLKNTAIMNSSQQESHANRSRSIDDETLEEVDNESIRE
IDQQMKSTQLDKNVANHSNICSTKSDEVDVTELHESIDTQSSEVNAYQPIEVLTSELK
AVTNRSIKTNPDHNVVNSDNPLKRPSKETPTSENKRSKGHETMVDVLVSEEQAVSPSS
DVICTNIKSIANEESSLALRNSIKVETNCNENSLNVTLDLDQQTITKEDGKGQVEHVQ
RQENQESMNKINSKSFTQDNIAQYKSVKKARPNNEGENNDYACNVEQASPVRNEVPGD
GIQIPSGTILLNSSKQTEKSKVDDLRSDEDEHGTVAQEKHQVGAINSRNKNNDRMDST
PIQGTEEESREVVMTEEGINVRLEDSGTCELNKNLKGPLKGDKDANINDDFVPVEENV
RDEGFLKSMEHAVSKETGLEEQPEVADISVLPEIRIPIFNSLKMQGSKSQIKEKLKKR
LQRNELMPPDSPPRMTENTNINAQNGLDTVPKTIGGKEKHHEIQLGQAHTEADGEPLL
GGDGNEDATSREATPSLKVHFFSKKSRRLVARLRGFTPGDLNGISVEERRNLRIELLD
FMMRLEYYSNRDNDMN"
rep_origin 757437..757667
/note="ARS225;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118354"
gene complement(757620..760043)
/gene="PPS1"
/locus_tag="YBR276C"
/db_xref="GeneID:852579"
mRNA complement(757620..760043)
/gene="PPS1"
/locus_tag="YBR276C"
/product="Pps1p"
/transcript_id="NM_001178624.3"
/db_xref="GI:398365844"
/db_xref="GeneID:852579"
CDS complement(757620..760043)
/gene="PPS1"
/locus_tag="YBR276C"
/EC_number="3.1.3.16"
/EC_number="3.1.3.48"
/note="Protein phosphatase with specificity for serine,
threonine, and tyrosine residues; has a role in the DNA
synthesis phase of the cell cycle"
/codon_start=1
/product="Pps1p"
/protein_id="NP_009835.3"
/db_xref="GI:398365845"
/db_xref="SGD:S000000480"
/db_xref="GeneID:852579"
/translation="MVLEVPSITPGELHDLMRLHQDAEWPECKKMFPWAHDISFGQPP
DFPHSLAIVKSQSDANNSALLRNSLEVNDIFQSWKVRTSFHREGDTCETGNDSNGFQY
PNNTKELLNLLKFQIRQLELQVDDVALENAATYCHNHSILPFLKVDPRGLSLELKRYS
RNKVGSNTTLKRSGQDVWGRRGLFRRFDLQCAKMIEMVDNIVIYCSRTGGSTDMQTES
APACSHEGNCPNCTTLALLLQICLMFVQKGYVGSGGSLYKTNLFICTYQNFNTDIPQT
LIGTPLLDNEFFKNNTPLNLCSSPSEIVCFNNVDKNMVLCEKLELNKLTSATRLEETG
LICGNTTDWHNYQIIKKNNISLTHRFEENTSIVNLKSLNYDTDNPTTSISQLYNIPNT
KEVWKLIIKCTSNSQMPSLTKIRTYLDLLLDDDASKSQEHLHLTFPASGSIGLGNLNI
QSVEILLNVCYLIFQVSQVQELLTFMYCEDGYTETSLLLTAYIIFHFNIPLQDALLRI
HPRPFFLFPSDLQILGHLQPVLREFSPQNGSNLKLYANALKFRDKSFQLHISSELFSS
IFFMKIPLESNFVNLKGPLPSRILRHLYLGSLDHAQNPALLKSLGITHIVSVGEVVSW
TLNKDKIAHPVRPHRAITMTNTNEVAGNTTCNKSRNRADTVVSDKQENGSNVVISENS
GFQICQIENLDDNGKDPLFHQIDKVLDFISNSEATGGKVLVHCMVGVSRSATVCIAEC
MRYLQCDLASAYLFVRVRRLNVIIQPNLFFVYELFKWWKKHYNREKDKTMDWHIICRG
IAEVNMKYT"
gene 760294..760899
/gene="DPB3"
/locus_tag="YBR278W"
/db_xref="GeneID:852580"
mRNA 760294..760899
/gene="DPB3"
/locus_tag="YBR278W"
/product="Dpb3p"
/transcript_id="NM_001178626.1"
/db_xref="GI:296142941"
/db_xref="GeneID:852580"
CDS 760294..760899
/gene="DPB3"
/locus_tag="YBR278W"
/EC_number="2.7.7.7"
/note="Third-largest subunit of DNA polymerase II (DNA
polymerase epsilon); required to maintain fidelity of
chromosomal replication and also for inheritance of
telomeric silencing; stabilizes the interaction of Pol
epsilon with primer-template DNA, positively affecting the
processivity of the polymerase and exonuclease activities
of Pol epsilon; mRNA abundance peaks at the G1/S boundary
of the cell cycle"
/codon_start=1
/product="Dpb3p"
/protein_id="NP_009837.1"
/db_xref="GI:6319754"
/db_xref="SGD:S000000482"
/db_xref="GeneID:852580"
/translation="MSNLVKEKAPVFPISKVKKIAKCDPEYVITSNVAISATAFAAEL
FVQNLVEESLVLAQLNSKGKTSLRLSLNSIEECVEKRDNFRFLEDAIKQLKKNSALDK
KRELNMQPGRSDQEVVIEEPELHEDDGVEEEEEEDEVSEEEEPVHNEELLDDSKDQQN
DKSTRSVASLLSRFQYKSALDVGEHSDSSDIEVDHTKSTDP"
gene 761257..762594
/gene="PAF1"
/locus_tag="YBR279W"
/db_xref="GeneID:852582"
mRNA 761257..762594
/gene="PAF1"
/locus_tag="YBR279W"
/product="Paf1p"
/transcript_id="NM_001178627.1"
/db_xref="GI:296142942"
/db_xref="GeneID:852582"
CDS 761257..762594
/gene="PAF1"
/locus_tag="YBR279W"
/note="Component of the Paf1p complex involved in
transcription elongation; binds to and modulates the
activity of RNA polymerases I and II; required for
expression of a subset of genes, including cell
cycle-regulated genes; involved in SER3 repression by
helping to maintain SRG1 transcription-dependent
nucleosome occupancy; homolog of human PD2/hPAF1"
/codon_start=1
/product="Paf1p"
/protein_id="NP_009838.1"
/db_xref="GI:6319756"
/db_xref="SGD:S000000483"
/db_xref="GeneID:852582"
/translation="MSKKQEYIAPIKYQNSLPVPQLPPKLLVYPESPETNADSSQLIN
SLYIKTNVTNLIQQDEDLGMPVDLMKFPGLLNKLDSKLLYGFDNVKLDKDDRILLRDP
RIDRLTKTDISKVTFLRRTEYVSNTIAAHDNTSLKRKRRLDDGDSDDENLDVNHIISR
VEGTFNKTDKWQHPVKKGVKMVKKWDLLPDTASMDQVYFILKFMGSASLDTKEKKSLN
TGIFRPVELEEDEWISMYATDHKDSAILENELEKGMDEMDDDSHEGKIYKFKRIRDYD
MKQVAEKPMTELAIRLNDKDGIAYYKPLRSKIELRRRRVNDIIKPLVKEHDIDQLNVT
LRNPSTKEANIRDKLRMKFDPINFATVDEEDDEDEEQPEDVKKESEGDSKTEGSEQEG
ENEKDEEIKQEKENEQDEENKQDENRAADTPETSDAVHTEQKPEEEKETLQEE"
gene complement(762784..764697)
/gene="SAF1"
/locus_tag="YBR280C"
/db_xref="GeneID:852583"
mRNA complement(762784..764697)
/gene="SAF1"
/locus_tag="YBR280C"
/product="SCF ubiquitin ligase complex subunit SAF1"
/transcript_id="NM_001178628.3"
/db_xref="GI:398365858"
/db_xref="GeneID:852583"
CDS complement(762784..764697)
/gene="SAF1"
/locus_tag="YBR280C"
/note="F-Box protein involved in proteasome-dependent
degradation of Aah1p during entry of cells into
quiescence; interacts with Skp1"
/codon_start=1
/product="SCF ubiquitin ligase complex subunit SAF1"
/protein_id="NP_009839.4"
/db_xref="GI:398365859"
/db_xref="SGD:S000000484"
/db_xref="GeneID:852583"
/translation="MSEVESREKEPDAGLSPDIVQATLPFLSSDDIKNLSQTNKYYNT
LLDFDHSKILWHELFHKAFGTLKTNDEPFQGRNSAEFKTCTETILREAFPTLSWQEVY
QLRAYDAKFYSWGYLKHGRLGYTASSNNELVATSLNGPSPRFKYGVNTPTEVPWFNSR
TTSRTSNFTPSEDPLSAIKKDGDEIIAQVSSGGFSFQILTESGNLYSSGSTFSGGLKG
PGPSGSQHDYNPFREMIHNMERSYPRITSRSNGSTVNTTGTFSGRRMSGSHPSTAYEP
GNATTAQHITIDSGGAPAASPGGSHSGVPRTTMPSMGPHENIYSQIEMLERSANKAVP
GNNHIRRMFARNSFPLYSGRDENLGSFNDIQFVAVSSGRSHFLAMDTDNNIYSWDSTE
SDQGVKIEFANLPSRATNPILKIASGWNFNCCYIYKVGLVAWKERDAIQKGESFAFAK
YEIVPNTNDVNGDSRIVDFACLQDNCVFFINNNGDKLWKYHNGLNQIVDLNIVGKLCK
INACFASLVLFTDTHCYTLKVTNGDVDKDSLTELDINENVISVASGDYHTVALTERGH
LYSWGIESQDCGCLGLGPSEKIVNELHIGNWEGQRNIRVVKPTKIELPEDYICVSVTA
GGWQTGALIIKKH"
gene complement(764970..767606)
/gene="DUG2"
/locus_tag="YBR281C"
/db_xref="GeneID:852584"
mRNA complement(764970..767606)
/gene="DUG2"
/locus_tag="YBR281C"
/product="glutamine amidotransferase subunit DUG2"
/transcript_id="NM_001178629.3"
/db_xref="GI:398365862"
/db_xref="GeneID:852584"
CDS complement(764970..767606)
/gene="DUG2"
/locus_tag="YBR281C"
/note="Component of glutamine amidotransferase (GATase
II); forms a complex with Dug3p to degrade glutathione
(GSH) and other peptides containing a gamma-glu-X bond in
an alternative pathway to GSH degradation by
gamma-glutamyl transpeptidase (Ecm38p)"
/codon_start=1
/product="glutamine amidotransferase subunit DUG2"
/protein_id="NP_009840.3"
/db_xref="GI:398365863"
/db_xref="SGD:S000000485"
/db_xref="GeneID:852584"
/translation="MYDSRGVALHSELIHRWNHAFSILSIVAFPKKRLLFAGSQDSKI
LVFDLPTYNLIHTIRLGESQEETHTRSSVLCLTGSEDENFLFSGGADSLVRIWSIGEK
TIRDDFLPVTEIATVYSVTDIGDIFSLAYLDSLETIVFGCQNASLLYVENLIQKIEKK
SSDGVENINKLPHRRYDKFFDSLGPTGYSSNSLSQTSLTSLQENCGAAIIEVPSENII
KYAHYGFIYSINKLCPRFNQLLEKSSRTSGAEHIISSAGDGISKLWEFSKDKGQNTVK
ISLINDKIDNEDSVISQTIEFPFLYCGLTDGIIKIWDLNTQQIISTLKTKHESDVISI
SVYMDHVFAIDESGITHFYQNQVNHWNPQQGKILSSEIFSKSNAGSVSLLTGGSDGSL
TLWDITSLLSAVPLSSNSPINASSTLQTTNLWAAYQSASLNNEEMLNTLRELISFQTV
SQSKDTTNTLSLRRCAIYLQQLFLKFGATNSQLFPLPDGGNPVVFAYFQGNGKVSQVK
GAKKKRILWYGHYDVISSGNTFNWNTDPFTLTCENGYLKGRGVSDNKGPLVSAIHSVA
YLFQQGELVNDVVFLVEGSEEIGSASLKQVCEKYHDIIGKDIDWILLSNSTWVDQEHP
CLNYGLRGVINAQIKVWSDKPDGHSGLNGGVYDEPMVNLVKIVSKLQNEQNEIMIPNF
YSPLKDLTEEEYQRFQKITELANIDENTTVQDLITNWTKPSLSMTTVKFSGPGNITVI
PKSVTMGISIRLVPEQSVEQVKRDLKAYLEESFKQLKSQNHLEIKVLNEAEGWLGDPT
NHAYQILKDEITTAWDVEPLLVREGGSISCLRMLERIFDAPAVQIPCGQSTDNGHLAN
ENLRIKNWSNLTEILSKVFNRL"
gene 768240..768680
/gene="MRPL27"
/locus_tag="YBR282W"
/db_xref="GeneID:852585"
mRNA 768240..768680
/gene="MRPL27"
/locus_tag="YBR282W"
/product="mitochondrial 54S ribosomal protein YmL27"
/transcript_id="NM_001178630.1"
/db_xref="GI:296142945"
/db_xref="GeneID:852585"
CDS 768240..768680
/gene="MRPL27"
/locus_tag="YBR282W"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL27"
/protein_id="NP_009841.1"
/db_xref="GI:6319759"
/db_xref="SGD:S000000486"
/db_xref="GeneID:852585"
/translation="MKGSPISQFSKTSINALTRPWKKYRDGELFYGLSKVGNKRVPLT
TKQGNKTMYKGTRASGIGRHTKFGGYVINWKKVRTYVTPDMVNFELKPYVNANVPPLK
HEFKGFSGGPLDPRLQLLKIKEYIVNGRVQSEGATDTSCYKERG"
gene complement(768943..770415)
/gene="SSH1"
/locus_tag="YBR283C"
/db_xref="GeneID:852586"
mRNA complement(768943..770415)
/gene="SSH1"
/locus_tag="YBR283C"
/product="Ssh1p"
/transcript_id="NM_001178631.1"
/db_xref="GI:296142946"
/db_xref="GeneID:852586"
CDS complement(768943..770415)
/gene="SSH1"
/locus_tag="YBR283C"
/note="Subunit of the Ssh1 translocon complex; Sec61p
homolog involved in co-translational pathway of protein
translocation; not essential"
/codon_start=1
/product="Ssh1p"
/protein_id="NP_009842.1"
/db_xref="GI:6319760"
/db_xref="SGD:S000000487"
/db_xref="GeneID:852586"
/translation="MSGFRLIDIVKPILPILPEVELPFEKLPFDDKIVYTIFAGLIYL
FAQFPLVGLPKATTPNVNDPIYFLRGVFGCEPRTLLEFGLFPNISSGLILQLLAGLKV
IKVNFKIQSDRELFQSLTKVFAIVQYVILTNIFIFAGYFGDDLSVVQIGLINFQLVGA
GIFTTLLAEVIDKGFGFSSGAMIINTVVIATNLVADTFGVSQIKVGEDDQTEAQGALI
NLIQGLRSKHKTFIGGIISAFNRDYLPNLTTTIIVLAIAIIVCYLQSVRVELPIRSTR
ARGTNNVYPIKLLYTGCLSVLFSYTILFYIHIFAFVLIQLVAKNEPTHIICKIMGHYE
NANNLLAVPTFPLSLLAPPTSFFKGVTQQPLTFITYSAFILVTGIWFADKWQAISGSS
ARDVALEFKDQGITLMGRREQNVAKELNKVIPIAAVTGASVLSLITVIGESLGLKGKA
AGIVVGIAGGFSLLEVITIEYQQSGGQSALNQVLGVPGAM"
gene 771239..773632
/locus_tag="YBR284W"
/db_xref="GeneID:852587"
mRNA 771239..773632
/locus_tag="YBR284W"
/product="metallo-dependent hydrolase superfamily protein"
/transcript_id="NM_001178632.3"
/db_xref="GI:398365878"
/db_xref="GeneID:852587"
CDS 771239..773632
/locus_tag="YBR284W"
/EC_number="3.5.4.-"
/note="Putative metallo-dependent hydrolase superfamily
protein; similar to AMP deaminases but lacks key catalytic
residues and does not rescue purine nucleotide metabolic
defect of quadruple aah1 ade8 amd1 his1 mutant; null
mutant exhibits longer telomeres, altered Ty mobility,
decreased resistance to rapamycin and wortmannin; induced
in response to hydrostatic pressure; not an essential
gene; YBR284W has a paralog, YJL070C, that arose from the
whole genome duplication"
/codon_start=1
/product="metallo-dependent hydrolase superfamily protein"
/protein_id="NP_009843.3"
/db_xref="GI:398365879"
/db_xref="SGD:S000000488"
/db_xref="GeneID:852587"
/translation="MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFD
GDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAET
PPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSC
PQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKE
FREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNC
RKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQ
FFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYI
NGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNI
FSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLS
QVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQ
ALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAP
PSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMG
FKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKN
KWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA"
gene 773922..774356
/locus_tag="YBR285W"
/db_xref="GeneID:852588"
mRNA 773922..774356
/locus_tag="YBR285W"
/product="hypothetical protein"
/transcript_id="NM_001178633.4"
/db_xref="GI:398365884"
/db_xref="GeneID:852588"
CDS 773922..774356
/locus_tag="YBR285W"
/note="hypothetical protein; YBR285W is not an essential
gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009844.4"
/db_xref="GI:398365885"
/db_xref="SGD:S000000489"
/db_xref="GeneID:852588"
/translation="MTIFSRFSYFDSLFSFKKQEPSPIEIIYCNENNGFINIKSLESP
TDDSMEADISDREMATILTRNRNNLGKVAIDKKGVNNHCIDLNELKKGLVANEHKLDN
DNSTRHQNTYSPEDSVEFDRFDDKQSRILKCSTRRSYLRYKK"
gene 774700..776313
/gene="APE3"
/locus_tag="YBR286W"
/gene_synonym="APY1"
/db_xref="GeneID:852589"
mRNA 774700..776313
/gene="APE3"
/locus_tag="YBR286W"
/gene_synonym="APY1"
/product="Ape3p"
/transcript_id="NM_001178634.1"
/db_xref="GI:296142949"
/db_xref="GeneID:852589"
CDS 774700..776313
/gene="APE3"
/locus_tag="YBR286W"
/gene_synonym="APY1"
/EC_number="3.4.11.15"
/note="Vacuolar aminopeptidase Y, processed to mature form
by Prb1p"
/codon_start=1
/product="Ape3p"
/protein_id="NP_009845.2"
/db_xref="GI:82795241"
/db_xref="SGD:S000000490"
/db_xref="GeneID:852589"
/translation="MHFSLKQLAVAAFYATNLGSAYVIPQFFQEAFQQEEPIENYLPQ
LNDDDSSAVAANIPKPHIPYFMKPHVESEKLQDKIKVDDLNATAWDLYRLANYSTPDY
GHPTRVIGSKGHNKTMEYILNVFDDMQDYYDVSLQEFEALSGKIISFNLSDAETGKSF
ANTTAFALSPPVDGFVGKLVEIPNLGCEEKDYASVVPPRHNEKQIALIERGKCPFGDK
SNLAGKFGFTAVVIYDNEPKSKEGLHGTLGEPTKHTVATVGVPYKVGKKLIANIALNI
DYSLYFAMDSYVEFIKTQNIIADTKHGDPDNIVALGAHSDSVEEGPGINDDGSGTISL
LNVAKQLTHFKINNKVRFAWWAAEEEGLLGSNFYAYNLTKEENSKIRVFMDYDMMASP
NYEYEIYDANNKENPKGSEELKNLYVDYYKAHHLNYTLVPFDGRSDYVGFINNGIPAG
GIATGAEKNNVNNGKVLDRCYHQLCDDVSNLSWDAFITNTKLIAHSVATYADSFEGFP
KRETQKHKEVDILNAQQPQFKYRADFLII"
gene 776571..777854
/locus_tag="YBR287W"
/db_xref="GeneID:852590"
mRNA 776571..777854
/locus_tag="YBR287W"
/product="hypothetical protein"
/transcript_id="NM_001178635.1"
/db_xref="GI:296142950"
/db_xref="GeneID:852590"
CDS 776571..777854
/locus_tag="YBR287W"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the ER; YBR287W is not
an essential gene"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_009846.1"
/db_xref="GI:6319764"
/db_xref="SGD:S000000491"
/db_xref="GeneID:852590"
/translation="MVETFSFAHLAYLVFESVLQVVIIALAGFWSASSGLLPKQSQKI
ISLLNVDLFTPCLIFSKLAKSLSMAKIFEIAIIPIFFGLTTGISFISGKIMSRILDLD
KDETNFVVANSVFGNSNSLPVSLTLSLAYTLPNLTWDQIPNDNRDNVASRGILYLLIF
QQIGQMLRWSWGYNKLMKWSGENTQHMPPSQVQSLLERTPNIDNEELVNEEQEEQELL
EEENNRMNSSFLSSSSIGDKIWQKSCTVFERIRANLNPPLYSMIFAVVVAAIGPLQRE
LFMEDGFINNTFAEAVTQLGSVSIPLILVVLGSNLYPSAEVFPKTVHHSKLLIGSIIG
RMILPSCFLLPIIAIAVKYINVSILDDPIFLVVGFLLTVSPPAIQLTQITQLNEFFEA
EMADILFWGYAVLSLPVSIIVVSGAIYVLQWANPT"
gene complement(778012..779463)
/gene="APM3"
/locus_tag="YBR288C"
/gene_synonym="YKS6"
/db_xref="GeneID:852591"
mRNA complement(778012..779463)
/gene="APM3"
/locus_tag="YBR288C"
/gene_synonym="YKS6"
/product="Apm3p"
/transcript_id="NM_001178636.4"
/db_xref="GI:398365906"
/db_xref="GeneID:852591"
CDS complement(778012..779463)
/gene="APM3"
/locus_tag="YBR288C"
/gene_synonym="YKS6"
/note="Mu3-like subunit of the clathrin associated protein
complex (AP-3); functions in transport of alkaline
phosphatase to the vacuole via the alternate pathway"
/codon_start=1
/product="Apm3p"
/protein_id="NP_009847.4"
/db_xref="GI:398365907"
/db_xref="SGD:S000000492"
/db_xref="GeneID:852591"
/translation="MYLSFYITDTKNKLIFQYLLGATAPSFKHLWTRVQSTCPQLLED
SSSDDYLDHSMVGRDLEVYKYFSVINKLNYWCLASTSKSKGPLDCFTFLETIDRILLE
YFDKDKLSIKKIVNNYDRISLIFNCCVEAGEPNVSDMLYVNKIKEAVPERSDLSKFIS
STAHNLQQAVQLPQQRQQQLQQNQISRGSNSLIENEEIVPWRTSRASKHENNELYVDL
LETFHVVFEKKKSHLRLLTGSIHGIVDVRSYLNDNPLVAVKLNTMGNDIGIPSLHDCV
EINDGVFSPSNITFIPPDGKFRLLEYSVDLSSQVKQSGVRMNSIGLMSLHFQNGLGKD
SDEFELSLNIENFKKVSQVDDLKIDLQFNVENADPNEIAYKIKILRNTHGRFENSIIM
GQGQWIFDKSTATGTVPVLRGCIEYENTGPNFTKKVDLQTVSLEYSYIGQSASGIYVE
AIDIVSGLTIGKNTKLYKGAKYKTQTGNFQVRL"
gene 779667..782384
/gene="SNF5"
/locus_tag="YBR289W"
/gene_synonym="HAF4; SWI10; TYE4"
/db_xref="GeneID:852592"
mRNA 779667..782384
/gene="SNF5"
/locus_tag="YBR289W"
/gene_synonym="HAF4; SWI10; TYE4"
/product="Snf5p"
/transcript_id="NM_001178637.4"
/db_xref="GI:398365912"
/db_xref="GeneID:852592"
CDS 779667..782384
/gene="SNF5"
/locus_tag="YBR289W"
/gene_synonym="HAF4; SWI10; TYE4"
/note="Subunit of the SWI/SNF chromatin remodeling
complex; involved in transcriptional regulation; functions
interdependently in transcriptional activation with Snf2p
and Snf6p; relocates to the cytosol under hypoxic
conditions"
/codon_start=1
/product="Snf5p"
/protein_id="NP_009848.4"
/db_xref="GI:398365913"
/db_xref="SGD:S000000493"
/db_xref="GeneID:852592"
/translation="MNNQPQGTNSVPNSIGNIFSNIGTPSFNMAQIPQQLYQSLTPQQ
LQMIQQRHQQLLRSRLQQQQQQQQQTSPPPQTHQSPPPPPQQSQPIANQSATSTPPPP
PAPHNLHPQIGQVPLAPAPINLPPQIAQLPLATQQQVLNKLRQQAIAKNNPQVVNAIT
VAQQQVQRQIEQQKGQQTAQTQLEQQRQLLVQQQQQQQLRNQIQRQQQQQFRHHVQIQ
QQQQKQQQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGQIPQSQQ
VPQVRSMSGQPPTNVQPTIGQLPQLPKLNLPKYQTIQYDPPETKLPYPTYWSDKKADT
DTLLYEQIIQRDKINKYSLIRETNGYDPFSIYGFSNKEYISRLWHTLKYYQDLKNTRM
KSITSTSQKIPSASIWGNGYSGYGNGITNTTTRVIPQVEVGNRKHYLEDKLKVYKQAM
NETSEQLVPIRLEFDQDRDRFFLRDTLLWNKNDKLIKIEDFVDDMLRDYRFEDATREQ
HIDTICQSIQEQIQEFQGNPYIELNQDRLGGDDLRIRIKLDIVVGQNQLIDQFEWDIS
NSDNCPEEFAESMCQELELPGEFVTAIAHSIREQVHMYHKSLALLGYNFDGSAIEDDD
IRSRMLPTITLDDVYRPAAESKIFTPNLLQISAAELERLDKDKDRDTRRKRRQGRSNR
RGMLALSGTSASNTSMNGVHNTVAAGNASSLPPGEILLPDIADIPRTFRTPVPSTLMP
GGVDVGPSVESYELRNTTTYKSRPDRPKPVSPPCYIIDHIPGHSLLLSIKLPGKVNTK
EEFAAAPNDTSSGTNAMLPSPESLKTKLNSNIRAGVTIPSIPNPIANHTVTNSPNPTL
QPVIPGGAASKSVPTPSLPIAPPVAPHDSEATLLTNSNNGSSNNNTQNT"
gene 782591..783556
/gene="BSD2"
/locus_tag="YBR290W"
/db_xref="GeneID:852593"
mRNA 782591..783556
/gene="BSD2"
/locus_tag="YBR290W"
/product="Bsd2p"
/transcript_id="NM_001178638.1"
/db_xref="GI:296142953"
/db_xref="GeneID:852593"
CDS 782591..783556
/gene="BSD2"
/locus_tag="YBR290W"
/note="Heavy metal ion homeostasis protein, facilitates
trafficking of Smf1p and Smf2p metal transporters to the
vacuole where they are degraded, controls metal ion
transport, prevents metal hyperaccumulation, functions in
copper detoxification"
/codon_start=1
/product="Bsd2p"
/protein_id="NP_009849.1"
/db_xref="GI:6319767"
/db_xref="SGD:S000000494"
/db_xref="GeneID:852593"
/translation="MPEQELLIGQEMNTLHAGSSTDGINVGNAGRTRDTQTGVEGETE
IGSDEEDSIEDEGSSSGGNSTTERLVPHQLREQAARHIGKIGRHFNILDRLFKKRTQQ
SSDIQQGAMFDGVFSNLSAKPDTTETEGNNEQDIPPTYDEAAADMAPSYYGMDLNNSD
IYYDEICIEGLPVGNIANLLWNIIVSTSFQFIGFLITYILHTSHAAKQGSRFGLGLTF
IGYGYSMIPNDVTSKVGKNKSLNRMELEDPNEFDDVRLNSQSTTQDKFESHLNHGLDE
EKQNIPWLAVFVAFLGLFITLKSIYDYIQVKKLEKKYLNQSQNQA"
gene complement(783673..784572)
/gene="CTP1"
/locus_tag="YBR291C"
/db_xref="GeneID:852594"
mRNA complement(783673..784572)
/gene="CTP1"
/locus_tag="YBR291C"
/product="Ctp1p"
/transcript_id="NM_001178639.1"
/db_xref="GI:296142954"
/db_xref="GeneID:852594"
CDS complement(783673..784572)
/gene="CTP1"
/locus_tag="YBR291C"
/note="Mitochondrial inner membrane citrate transporter,
member of the mitochondrial carrier family"
/codon_start=1
/product="Ctp1p"
/protein_id="NP_009850.1"
/db_xref="GI:6319768"
/db_xref="SGD:S000000495"
/db_xref="GeneID:852594"
/translation="MSSKATKSDVDPLHSFLAGSLAGAAEACITYPFEFAKTRLQLID
KASKASRNPLVLIYKTAKTQGIGSIYVGCPAFIIGNTAKAGIRFLGFDTIKDMLRDSE
TGELSGTRGVIAGLGAGLLESVAAVTPFEAIKTALIDDKQSATPKYHNNGRGVVRNYS
SLVRDKGFSGLYRGVLPVSMRQAANQAVRLGCYNKIKTLIQDYTDSPKDKPLSSGLTF
LVGAFSGIVTVYSTMPLDTVKTRMQSLDSTKYSSTMNCFATIFKEEGLKTFWKGATPR
LGRLVLSGGIVFTIYEKVLVMLA"
gene 787006..788430
/gene="VBA2"
/locus_tag="YBR293W"
/db_xref="GeneID:852596"
mRNA 787006..788430
/gene="VBA2"
/locus_tag="YBR293W"
/product="Vba2p"
/transcript_id="NM_001178641.3"
/db_xref="GI:398365922"
/db_xref="GeneID:852596"
CDS 787006..788430
/gene="VBA2"
/locus_tag="YBR293W"
/note="Permease of basic amino acids in the vacuolar
membrane"
/codon_start=1
/product="Vba2p"
/protein_id="NP_009852.3"
/db_xref="GI:398365923"
/db_xref="SGD:S000000497"
/db_xref="GeneID:852596"
/translation="MSISNWITTAYLITSTSFQPLYGSFSDALGRRNCLFFANGAFTI
GCLACGFSKNIYMLSFMRALTGIGGGGLITLSTIVNSDVIPSSKRGIFQAFQNLLLGF
GAICGASFGGTIASSIGWRWCFLIQVPISVISSILMNYYVPNQKEYNRQNSSIFQNPG
KILRDIDVMGSILIITGLTLQLLYLSLGCSTSKLSWTSPSVLLLLVGSVIILLLFILH
ERKTSARAIIPMELVNSSYSVVVLSISILVGFASYAYLFTLPLFFQIVLGDSTAKAGL
RLTIPSLFTPVGSLITGFSMSKYNCLRLLLYIGISLMFLGNFLFLFIEKTSPNWLIGL
FLIPANLGQGITFPTTLFTFIFMFSKSDQATATSTLYLFRSIGSVWGVAISAGVIQLS
FAGLLRSNLKGLLDENKIKKLIVQLSANSSYIGSLHGEVKNTVIKSFDEATKRAHLMS
TLLSSLALILCILKDNLAKPKTRR"
gene 789235..791814
/gene="SUL1"
/locus_tag="YBR294W"
/gene_synonym="SFP2"
/db_xref="GeneID:852597"
mRNA 789235..791814
/gene="SUL1"
/locus_tag="YBR294W"
/gene_synonym="SFP2"
/product="Sul1p"
/transcript_id="NM_001178642.3"
/db_xref="GI:398365928"
/db_xref="GeneID:852597"
CDS 789235..791814
/gene="SUL1"
/locus_tag="YBR294W"
/gene_synonym="SFP2"
/note="High affinity sulfate permease of the SulP anion
transporter family; sulfate uptake is mediated by specific
sulfate transporters Sul1p and Sul2p, which control the
concentration of endogenous activated sulfate
intermediates"
/codon_start=1
/product="Sul1p"
/protein_id="NP_009853.3"
/db_xref="GI:398365929"
/db_xref="SGD:S000000498"
/db_xref="GeneID:852597"
/translation="MSRKSSTEYVHNQEDADIEVFESEYRTYRESEAAENRDGLHNGD
EENWKVNSSKQKFGVTKNELSDVLYDSIPAYEESTVTLKEYYDHSIKNNLTAKSAGSY
LVSLFPIIKWFPHYNFTWGYADLVAGITVGCVLVPQSMSYAQIASLSPEYGLYSSFIG
AFIYSLFATSKDVCIGPVAVMSLQTAKVIAEVLKKYPEDQTEVTAPIIATTLCLLCGI
VATGLGILRLGFLVELISLNAVAGFMTGSAFNIIWGQIPALMGYNSLVNTREATYKVV
INTLKHLPNTKLDAVFGLIPLVILYVWKWWCGTFGITLADRYYRNQPKVANRLKSFYF
YAQAMRNAVVIVVFTAISWSITRNKSSKDRPISILGTVPSGLNEVGVMKIPDGLLSNM
SSEIPASIIVLVLEHIAISKSFGRINDYKVVPDQELIAIGVTNLIGTFFHSYPATGSF
SRSALKAKCNVRTPFSGVFTGGCVLLALYCLTDAFFFIPKATLSAVIIHAVSDLLTSY
KTTWTFWKTNPLDCISFIVTVFITVFSSIENGIYFAMCWSCAMLLLKQAFPAGKFLGR
VEVAEVLNPTVQEDIDAVISSNELPNELNKQVKSTVEVLPAPEYKFSVKWVPFDHGYS
RELNINTTVRPPPPGVIVYRLGDSFTYVNCSRHYDIIFDRIKEETRRGQLITLRKKSD
RPWNDPGEWKMPDSLKSLFKFKRHSATTNSDLPISNGSSNGETYEKPLLKVVCLDFSQ
VAQVDSTAVQSLVDLRKAVNRYADRQVEFHFAGIISPWIKRSLLSVKFGTTNEEYSDD
SIIAGHSSFHVAKVLKDDVDYTDEDSRISTSYSNYETLCAATGTNLPFFHIDIPDFSK
WDV"
rep_origin 792164..792388
/note="ARS228;
Autonomously Replicating Sequence"
/db_xref="SGD:S000118355"
gene 792849..796499
/gene="PCA1"
/locus_tag="YBR295W"
/gene_synonym="CAD2; PAY2"
/db_xref="GeneID:852598"
mRNA 792849..796499
/gene="PCA1"
/locus_tag="YBR295W"
/gene_synonym="CAD2; PAY2"
/product="cation-transporting P-type ATPase PCA1"
/transcript_id="NM_001178643.2"
/db_xref="GI:330443480"
/db_xref="GeneID:852598"
CDS 792849..796499
/gene="PCA1"
/locus_tag="YBR295W"
/gene_synonym="CAD2; PAY2"
/EC_number="3.6.3.3"
/note="Cadmium transporting P-type ATPase; may also have a
role in copper and iron homeostasis; stabilized by Cd
binding, which prevents ubiquitination; S288C and other
lab strains contain a G970R mutation which eliminates Cd
transport function"
/codon_start=1
/product="cation-transporting P-type ATPase PCA1"
/protein_id="NP_009854.2"
/db_xref="GI:330443481"
/db_xref="SGD:S000000499"
/db_xref="GeneID:852598"
/translation="MKPEKLFSGLGTSDGEYGVVNSENISIDAMQDNRGECHRRSIEM
HANDNLGLVSQRDCTNRPKITPQECLSETEQICHHGENRTKAGLDVDDAETGGDHTNE
SRVDECCAEKVNDTETGLDVDSCCGDAQTGGDHTNESCVDGCCVRDSSVMVEEVTGSC
EAVSSKEQLLTSFEVVPSKSEGLQSIHDIRETTRCNTNSNQHTGKGRLCIESSDSTLK
KRSCKVSRQKIEVSSKPECCNISCVERIASRSCEKRTFKGSTNVGISGSSSTDSLSEK
FFSEQYSRMYNRYSSILKNLGCICNYLRTLGKESCCLPKVRFCSGEGASKKTKYSYRN
SSGCLTKKKTHGDKERLSNDNGHADFVCSKSCCTKMKDCAVTSTISGHSSSEISRIVS
MEPIENHLNLEAGSTGTEHIVLSVSGMSCTGCESKLKKSFGALKCVHGLKTSLILSQA
EFNLDLAQGSVKDVIKHLSKTTEFKYEQISNHGSTIDVVVPYAAKDFINEEWPQGVTE
LKIVERNIIRIYFDPKVIGARDLVNEGWSVPVSIAPFSCHPTIEVGRKHLVRVGCTTA
LSIILTIPILVMAWAPQLREKISTISASMVLATIIQFVIAGPFYLNALKSLIFSRLIE
MDLLIVLSTSAAYIFSIVSFGYFVVGRPLSTEQFFETSSLLVTLIMVGRFVSELARHR
AVKSISVRSLQASSAILVDKTGKETEINIRLLQYGDIFKVLPDSRIPTDGTVISGSSE
VDEALITGESMPVPKKCQSIVVAGSVNGTGTLFVKLSKLPGNNTISTIATMVDEAKLT
KPKIQNIADKIASYFVPTIIGITVVTFCVWIAVGIRVEKQSRSDAVIQAIIYAITVLI
VSCPCVIGLAVPIVFVIASGVAAKRGVIFKSAESIEVAHNTSHVVFDKTGTLTEGKLT
VVHETVRGDRHNSQSLLLGLTEGIKHPVSMAIASYLKEKGVSAQNVSNTKAVTGKRVE
GTSYSGLKLQGGNCRWLGHNNDPDVRKALEQGYSVFCFSVNGSVTAVYALEDSLRADA
VSTINLLRQRGISLHILSGDDDGAVRSMAARLGIESSNIRSHATPAEKSEYIKDIVEG
RNCDSSSQSKRPVVVFCGDGTNDAIGLTQATIGVHINEGSEVAKLAADVVMLKPKLNN
ILTMITVSQKAMFRVKLNFLWSFTYNLFAILLAAGAFVDFHIPPEYAGLGELVSILPV
IFVAILLRYAKI"
gene complement(796798..798522)
/gene="PHO89"
/locus_tag="YBR296C"
/gene_synonym="ITN1"
/db_xref="GeneID:852599"
mRNA complement(796798..798522)
/gene="PHO89"
/locus_tag="YBR296C"
/gene_synonym="ITN1"
/product="Pho89p"
/transcript_id="NM_001178644.1"
/db_xref="GI:296142958"
/db_xref="GeneID:852599"
CDS complement(796798..798522)
/gene="PHO89"
/locus_tag="YBR296C"
/gene_synonym="ITN1"
/note="Na+/Pi cotransporter, active in early growth phase;
similar to phosphate transporters of Neurospora crassa;
transcription regulated by inorganic phosphate
concentrations and Pho4p; mutations in related human
transporter genes hPit1 and hPit2 are associated with
hyperphosphatemia-induced calcification of vascular tissue
and familial idiopathic basal ganglia calcification"
/codon_start=1
/product="Pho89p"
/protein_id="NP_009855.1"
/db_xref="GI:6319773"
/db_xref="SGD:S000000500"
/db_xref="GeneID:852599"
/translation="MALHQFDYIFAIAMLFAFLDAFNIGANDVANSFASSISSRSLKY
WQAMVLAGLCEFLGAVLAGARVSGTIKNNIIDSSIFTNDPAVLMLTMTSALIGSSCWL
TFATAIGMPVSTTHSIVGGTIGAGIAAGGANGVVWGWSGVSQIIASWFIAPILAGAIA
AIVFSISRFSVLEVKSLERSIKNALLLVGVLVFATFSILTMLIVWKGSPNLHLDDLSE
TETAVSIVLTGAIASIVYFIFFYPFYRRKVLDQDWTLKLIDIFRGPSFYFKSTDDIPP
MPEGHQLTIDYYEGRRNLGTTVSVEDEENKAASNSNDSVKNKEDIQEVDLVRTETEPE
TKLSTKQYWWSLLKQGPKKWPLLFWLVISHGWTQDVIHAQVNDRDMLSGDLKGMYERS
KFYDNRVEYIYSVLQAITAATMSFAHGANDVANATGPLSAVYVIWKTNTIGAKSEVPV
WVLAYGGVALVIGCWTYGYNIIKNLGNKMILQSPSRGFSIELAVAITTVMATQLGIPT
STTQIAVGGIVAVGLCNKDLKSVNWRMVAWCYSGWFLTLPIAGLIAGIINGIILNAPR
FGVEYQMT"
gene complement(800123..800242)
/locus_tag="YBR296C-A"
/db_xref="GeneID:1466451"
mRNA complement(800123..800242)
/locus_tag="YBR296C-A"
/product="hypothetical protein"
/transcript_id="NM_001184587.3"
/db_xref="GI:398365950"
/db_xref="GeneID:1466451"
CDS complement(800123..800242)
/locus_tag="YBR296C-A"
/note="hypothetical protein; identified by gene-trapping,
microarray-based expression analysis, and genome-wide
homology searching"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878055.3"
/db_xref="GI:398365951"
/db_xref="SGD:S000028605"
/db_xref="GeneID:1466451"
/translation="MKVLDDWFSRKFSKAVHGNNHGTISLSTLSYIRVHKLVK"
gene 800523..801929
/gene="MAL33"
/locus_tag="YBR297W"
/db_xref="GeneID:852600"
mRNA 800523..801929
/gene="MAL33"
/locus_tag="YBR297W"
/product="Mal33p"
/transcript_id="NM_001178645.3"
/db_xref="GI:398365954"
/db_xref="GeneID:852600"
CDS 800523..801929
/gene="MAL33"
/locus_tag="YBR297W"
/note="MAL-activator protein, part of complex locus MAL3;
nonfunctional in genomic reference strain S288C"
/codon_start=1
/product="Mal33p"
/protein_id="NP_009856.3"
/db_xref="GI:398365955"
/db_xref="SGD:S000000501"
/db_xref="GeneID:852600"
/translation="MTLVKYACDYCRVRRVKCDGKKPCSRCIEHNFDCTYQQPLKKRG
SKPIGTRSLKYIPKAKMFIDNKSCTAAAEILMKVPKKVIDQCLRLYHDNLYVIWPLLS
YDDLHKLLDEEYNDHYVYWFLVALSAANLSDLQSELESEGGFSFTGKQLAVLCMSSRQ
QFDDLSGRDIFRIMTYYCLLRCFSQSSDVRNSYRLCREAIGLVIVAGLHREKAYESLS
FREQQLLRKVYYLLLLTERYYSVYVHCVTSLDTTIAPPQPEFVTDPRLSLDSFFEMIR
VFTVPGKCFFDALATESTSGSCTEDSLKKIWKELHTASLEIEPWSYGYVDISFSRHWI
RALAWKLVFQMNGTKFFSNANNAHILVEIAKDMLDDIFLTPNNLYDVHGPGIPMKSLE
VANALVDIVNKYDHNMKLEAWNILCDVSKFVFSLKHCNHKMFQRFSTKCQSALIDLPI
SRPLRLNDDSKDEDDIIP"
gene complement(802631..804475)
/gene="MAL31"
/locus_tag="YBR298C"
/db_xref="GeneID:852601"
mRNA complement(802631..804475)
/gene="MAL31"
/locus_tag="YBR298C"
/product="Mal31p"
/transcript_id="NM_001178646.1"
/db_xref="GI:296142961"
/db_xref="GeneID:852601"
CDS complement(802631..804475)
/gene="MAL31"
/locus_tag="YBR298C"
/note="Maltose permease, high-affinity maltose transporter
(alpha-glucoside transporter); encoded in the MAL3 complex
locus; member of the 12 transmembrane domain superfamily
of sugar transporters; functional in genomic reference
strain S288C"
/codon_start=1
/product="Mal31p"
/protein_id="NP_009857.1"
/db_xref="GI:6319775"
/db_xref="SGD:S000000502"
/db_xref="GeneID:852601"
/translation="MKGLSSLINRKKDRNDSHLDEIENGVNATEFNSIEMEEQGKKSD
FDLSHLEYGPGSLIPNDNNEEVPDLLDEAMQDAKEADESERGMPLMTALKTYPKAAAW
SLLVSTTLIQEGYDTAILGAFYALPVFQKKYGSLNSNTGDYEISVSWQIGLCLCYMAG
EIVGLQMTGPSVDYMGNRYTLIMALFFLAAFIFILYFCKSLGMIAVGQALCGMPWGCF
QCLTVSYASEICPLALRYYLTTYSNLCWAFGQLFAAGIMKNSQNKYANSELGYKLPFA
LQWIWPLPLAVGIFFAPESPWWLVKKGRIDQARRSLERTLSGKGPEKELLVSMELDKI
KTTIEKEQKMSDEGTYWDCVKDGINRRRTRIACLCWIGQCSCGASLIGYSTYFYEKAG
VSTDTAFTFSIIQYCLGIAATFISWWASKYCGRFDLYAFGLAFQAIMFFIIGGLGCSD
THGAKMGSGALLMVVAFFYNLGIAPVVFCLVSEIPSSRLRTKTIILARNAYNVIQVVV
TVLIMYQLNSEKWNWGAKSGFFWGGFCLATLAWAVVDLPETAGRTFIEINELFRLGVP
ARKFKSTKVDPFAAAKAAAAEINVKDPKEDLETSVVDEGRNTSSVVNK"
gene complement(805035..805256)
/locus_tag="YBR298C-A"
/db_xref="GeneID:1466452"
mRNA complement(805035..805256)
/locus_tag="YBR298C-A"
/product="hypothetical protein"
/transcript_id="NM_001184588.1"
/db_xref="GI:296142962"
/db_xref="GeneID:1466452"
CDS complement(805035..805256)
/locus_tag="YBR298C-A"
/note="hypothetical protein; identified by gene-trapping,
microarray-based expression analysis, and genome-wide
homology searching"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_878056.1"
/db_xref="GI:33438774"
/db_xref="SGD:S000028606"
/db_xref="GeneID:1466452"
/translation="MELFIPCPERLKKMMLKEELRKELLILRCLYHPTIQIMLPTLGT
LGTEKRKEKYALSLFEPILNCVGSAKTSG"
gene 805351..807105
/gene="MAL32"
/locus_tag="YBR299W"
/db_xref="GeneID:852602"
mRNA 805351..807105
/gene="MAL32"
/locus_tag="YBR299W"
/product="Mal32p"
/transcript_id="NM_001178647.3"
/db_xref="GI:398365966"
/db_xref="GeneID:852602"
CDS 805351..807105
/gene="MAL32"
/locus_tag="YBR299W"
/EC_number="3.2.1.20"
/note="Maltase (alpha-D-glucosidase), inducible protein
involved in maltose catabolism; encoded in the MAL3
complex locus; functional in genomic reference strain
S288C; hydrolyzes the disaccharides maltose, turanose,
maltotriose, and sucrose"
/codon_start=1
/product="Mal32p"
/protein_id="NP_009858.3"
/db_xref="GI:398365967"
/db_xref="SGD:S000000503"
/db_xref="GeneID:852602"
/translation="MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSK
LQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMK
FITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGG
SAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGL
YSKRPGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGE
VAHGSDNALYTSAARYEVSEVFSFTHVELGTSPFFRYNIVPFTLKQWKEAIASNFLFI
NGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIG
QINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTK
DKPNAGFTGPDVKPWFFLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIY
GYDFQFIDLDSDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNYDDT
DVSSRVLKPWEGRIYLVK"
gene 809057..809419
/gene="PAU24"
/locus_tag="YBR301W"
/gene_synonym="DAN3"
/db_xref="GeneID:852603"
mRNA 809057..809419
/gene="PAU24"
/locus_tag="YBR301W"
/gene_synonym="DAN3"
/product="Pau24p"
/transcript_id="NM_001178649.3"
/db_xref="GI:398365970"
/db_xref="GeneID:852603"
CDS 809057..809419
/gene="PAU24"
/locus_tag="YBR301W"
/gene_synonym="DAN3"
/note="Cell wall mannoprotein with similarity to Tir1p,
Tir2p, Tir3p, and Tir4p; member of the seripauperin
multigene family encoded mainly in subtelomeric regions;
expressed under anaerobic conditions, completely repressed
during aerobic growth"
/codon_start=1
/product="Pau24p"
/protein_id="NP_009860.3"
/db_xref="GI:398365971"
/db_xref="SGD:S000000505"
/db_xref="GeneID:852603"
/translation="MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIR
AHLAQYYSFQVAHPTETYPVEIAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSSRL
KPAISSALSKDGIYTIAN"
gene complement(810340..811479)
/gene="COS2"
/locus_tag="YBR302C"
/db_xref="GeneID:852605"
mRNA complement(810340..811479)
/gene="COS2"
/locus_tag="YBR302C"
/product="Cos2p"
/transcript_id="NM_001178650.1"
/db_xref="GI:296142965"
/db_xref="GeneID:852605"
CDS complement(810340..811479)
/gene="COS2"
/locus_tag="YBR302C"
/note="hypothetical protein, member of the DUP380
subfamily of conserved, often subtelomerically-encoded
proteins"
/codon_start=1
/product="Cos2p"
/protein_id="NP_009861.1"
/db_xref="GI:6319779"
/db_xref="SGD:S000000506"
/db_xref="GeneID:852605"
/translation="MKENELKNEKSVDVLSFKQLESQKIVLPQDLFRSSFTWFCYEIY
KSLAFRIWMLLWLPLSVWWKLSNNCIYPLIVSLLVLFLGPIFVLVICGLSRKRSLSKQ
LIQFCKEITENTPSSDPHDWEVVAANLNSYLYENNVWNTKYFFFNAMVCQEAFRTTLL
EPFSLKKDKAAKVKSFKDSVPYIEEALGVYFTEVEKQWKLFNTEKSWSPVGLEDAKLP
KEAYRFKLTWFLKRISNIFMLIPFLNFLCCIYVSRGMCLLLRTLYLGWILFMLVQGFQ
NIRVLIMSMEHKMQFLSTIINEQESGANGWDEIARKMNRYLFEKKAWKNEEFFFDGID
CEWFFNHFFYRVLSAKKSMWPLPLNVELWPYIKEAQLSRSEVLLV"
telomere 812379..813184
/note="TEL02R; Telomeric region on the right arm of
Chromosome II; composed of an X element core sequence, X
element combinatorial repeats, and a short terminal
stretch of telomeric repeats"
/db_xref="SGD:S000028940"
repeat_region 812379..812848
/note="TEL02R-XC; Telomeric X element Core sequence on the
right arm of Chromosome II, contains an ARS consensus
sequence and an Abf1p binding site consensus sequence"
/rpt_family="X element Core sequence"
/db_xref="SGD:S000028942"
repeat_region 812849..813137
/note="TEL02R-XR; Telomeric X element combinatorial Repeat
region on the right arm of Chromosome II; contains repeats
of the D, C, B and A types, as well as Tbf1p binding
sites; formerly called SubTelomeric Repeats"
/rpt_family="X element Combinatorial Repeats"
/db_xref="SGD:S000028943"
repeat_region 813138..813184
/note="TEL02R-TR; Terminal stretch of telomeric repeats on
the right arm of Chromosome II"
/rpt_family="Telomeric Repeat"
/db_xref="SGD:S000028941"
ORIGIN
1 aaatagccct catgtacgtc tcctccaagc cctgttgtct cttacccgga tgttcaacca
61 aaagctactt actaccttta ttttatgttt actttttata ggttgtcttt ttatcccact
121 tcttcgcact tgtctctcgc tactgccgtg caacaaacac taaatcaaaa caatgaaata
181 ctactacatc aaaacgcatt ttccctagaa aaaaaatttt cttacaatat actatactac
241 acaatacata atcactgact ttcgtaacaa caatttcctt cactctccaa cttctctgct
301 cgaatctcta catagtaata ttatatcaaa tctaccgtct ggaacatcat cgctatccag
361 ctctttgtga accgctacca tcagcatgta cagtggtacc ctcgtgttat ctgcagcgag
421 aacttcaacg tttgccaaat caagccaatg tggtaacaac cacatctccg aaatctgctc
481 caaaagatat tccagtttct gccgaaatgt tttattgtag aacagcccta tcagcatcga
541 caggaatgcc gtccaatgcg gcactttaga tggggtaact cccagcgcaa gctgatctcg
601 caagtgcatt cctagactta attcatatct gctcctcaac tgtcgatgat gcctgctaaa
661 ctgcagcttg acgtactgcg gaccctgcag tccagcgctc gtcatggaac gcaaacgctg
721 aaaaactcca actttctcga gcgcttccac aaagaccgta tcgtcttttg cctcccattc
781 ttcccggcac tttttttcgt cccagttcaa aaagtactgc agcacctctg tcttcgattc
841 acgcaagttg ctccatactt tataatacaa ctctttgatc tgccttccag acatgcggaa
901 aacttggctc ccttgcttgc ctcttgtcga atccaataca ctaattgttt ctcttcttct
961 agtaatggcc aggtaccaag cataatttct ctgtatctga gagtagatct ctctcctttt
1021 tacgctaaaa tatttcaaat atcctacagg gtccccatga tatggctcga tgtcttccaa
1081 gtattctttg tattcctcat catttcgcag cattctctcc acagctagtg cttcccaagc
1141 tatcctccga tacgatactt tctggccagc ccaacagaca cagagcccga acatcttttg
1201 acagcccttg cataatccgt attgtgtgaa tactccctct gggcagaagt atatgtcaat
1261 accatagagg aaaagatgtt taatttcgtc agaccgaaat ccaagaaact gtaagacatt
1321 catattctcg gaagtattgg gaaattgtgc tttcagtttc tttctctcta ggaaaaccat
1381 ttgactccct ttccgcttat acgactcttt gttaatgtcg gtgactggat ggaatctatt
1441 atcctcagca ttgccatctt tattggcgtc ctccttggca ctagcgttgg tactttcagt
1501 ggtagtggca ttagtgctgg agttggtgct agcagtggta gtggcattag tgctggagtt
1561 ggtgctagca gtggtagtag cactagtgtt ggagtcggta ctttcggtgg tagtagcact
1621 agtgttggag ttggtacttt cagtggtagt cgcactagtc ctgacgttga tgctagcagt
1681 ggtagtagca ttagtgttgg agtcggtact ttcggtggta gtagcactag tgttggagtt
1741 ggtactttca gtggtagtag cattagtgct agagttgata ctttcagtgg tagtagcact
1801 agtcctgacg ttgatgctgg cagtggtagt agcactagtc ctgacgttgg tgctggcagt
1861 ggtagtagca ctagtcctga cgttggtgct ggcagtggta gtagcattag tgctggagtt
1921 ggtagtcgca ttggtagtag cactagtcct gacgttggtg ctggcagtgg tagtagcatt
1981 agtgctggag ttggtagtcg cattggtact ggcattagtg ttggagttgg tactttcagt
2041 ggtagtcgca ctagtcctga cgttgatgct ggcagtggta gtagcattag tgctggagtt
2101 ggtactttca gtggtagtcg cactagtcct gacgttgatg ctggcagtgg tagtagcatt
2161 agtgctggag ttggtacttt cagtggtagt cgcactagtc ctgacgttga tgctggcagt
2221 ggtagtagca ttagtgctgg agttggtact ttcagtggta gtagcattag tgttggagtt
2281 ggtactttca gtggtagtcg cactagtcct gacgttgatg ctggcagtgg tagtcgcact
2341 agtcctgacg ttgatgctgg cagtggtagt agcattagtg ctggagttgg tagtcgcatt
2401 ggtactggca ttagcactac catgaatgca cgtgtcgctg tcctcatcac tgctgcaata
2461 ctttctgcac ctgtcactgc tattgctctc ctggaagcta gacggtaacg caacgatcga
2521 catggaagct gtcgcctgat tttcagccaa tctgtccatt ctttctatca gttccactgt
2581 gtcagcagac aggtctgtcc tggagccaca gcatccaaca tgctggccct ttttttcctt
2641 tctttgattc aagtccatag aactcgcgta cctgttcggt tatacagcct tccttaatcg
2701 gtggtaattc acccttacga ttccttgccg cccaactgtt ttttctagat aatagataac
2761 agaggccccc atctcttagt ctccctacgc cttgaatgag ctcaataata ttaagtctat
2821 tatcaagcat gatcaccatc atcaattgct taatgtcaat tccttcagtc actaatttcg
2881 ttccgatgag aacttgcatg ctaccgtcag tgacaaactc ctttgtgcga gacacctttt
2941 ctgcagcacc caagcttccc gtgtatccat accaccctaa aatactttct ccaagagcag
3001 gccaattctt ccacttcgtt ggttgtgctt gcaactacaa tggccttcga ctctggttca
3061 atttcaaaga gggctaaaag aagcttcagt gcttcttcgg gctgtgattc cactttcttc
3121 caaattttat gaacatgccc taaaggcacc tcggatttct ccttgattag attaaacatc
3181 cgtgttggat agctggatag acctctgctg agatcttccg accgtttgag ctcgttgatg
3241 tccatcgact tcttggccag tcccgtaagc ccaatacgct gcaacgcagc atcagcaaca
3301 gcctcagggg ctgtgccgct caaaaagatt gctttctcaa aagcgtcaaa atcaaggtta
3361 gttatgcccc caaattgcga ctgccggtag acctccgttt caaagttgtg aaactcatct
3421 acaatgaggt aacccaattt tacgttgttg gtcctaaagg tgcactcaac aatattctcc
3481 cacgcagcta tcctgtctgt gaaattagtg ctagcaagat catcgtagat ccccacgtat
3541 aaatcagtaa cgccatcgca accttcttca ataaagtttc ttacaggggc cacattcaag
3601 caaccgcgtc ggcccaacct gatcatgcaa ttagcaagca acactgtgta cggtacaaac
3661 agaaacgaca catatttcac gtcgccctta gatgccagtg ctatcaaggg gagatgaaat
3721 aactccgtct taccatagcc cggtggggcc tgtactgcca cagagggtgt gtctgccatg
3781 tatatttcat gacataagcg caactgatgc aagtccctga attcaaagga gctgccaaag
3841 agtttccggc ctgcgacgag gatatcgttt gtactcttgg gctctcgggg cctttttcgc
3901 gttactcttg aaattttttg atcatgatct gaactcgccg cctcacctgc cactacgtct
3961 tccgcattcc gagtactaga gaatgaacaa tggtagtcgc tttcaaggcc taaccattga
4021 atccagcgct cggaagtgag tccgtcaagc gtctttagtc gaggctccga tgaaccgttc
4081 ttgttgtatc gtcgacgtat acgttgcgct gtagctctgg ataacggtaa gcgtatcacc
4141 gtaagctcgt caattatttt tgagagccgc ggtcattttg ttagtatctc ttctcaactt
4201 gggcagcaca catgcaaaac atcacccaat cggtcctttt tgttcatcat atcgttacat
4261 atctgtgaaa agtactttat ctcagtgggt ttacgtgggc atagatcacg cttcagccgc
4321 tctgtgtcga ctttcttttc gccaggtaaa cttgcttggt atgcagaaaa aatcgatagc
4381 tcatctacgt gtagtaacaa gaacatgtag ggtgccaaat tgtatccata tttccttatg
4441 gtgcttttct gaagactcct tacaataggt gtgccagaaa caaagtcagt gaaagtacgc
4501 atcgtagagc tgtcgttcgg cctggcactc gctatttcgt aacaacgttc caggacacgg
4561 aaactcaact cattatagta tcctctgttg aggtaaaaaa gagaaagggt atcgtaatcc
4621 tttctattga atttcaaagt atgcacttga aacaacgtgt agaccatcaa gttgattttc
4681 ttgggaataa gatactttga agggattggt ccgccctgga aatctggttc gtcttcaaca
4741 aacgtcagga acttttgtac atttttcccg accatgacgg aaacgacaat tttttcaaaa
4801 gaccttttcc tatccattgc accagttctg aattttacca ctttgattag accagacttt
4861 tcgtcttcgt agaatgaccg cacttccgtg gggatcgatt caaataaagt tattgaggga
4921 caatgtacca agtcgttttt gttatttaga gccgactcaa actcgtcaaa gtttgctttt
4981 tcaaacttac gcctatcgga aactttcatt ttatttttgt aagtttcgaa attaacaata
5041 gtatgttgat tgctatgctt tttgacaaga aatccatcaa tataaacaaa agattgtcca
5101 gtttccgtct tatcatcatc taagaatgta ataattaagc tactctattg agaagaagca
5161 gaatctgcgc tatgcaggtg caaatctcca gcagcagcaa agaaaattca gttaataaga
5221 aatctcacta agataagcga ctgtctgtcc ccttcaagca caacatagaa aacagaagga
5281 tgtctcattc atcgcttgat ttccggcctg caaaaataaa gtagtcggta cgtactttcg
5341 ttttcaattt ccatggtgca cagtatctta actatctgct tagtcgagga gaaccaggat
5401 tctgttcgtt gctcagccgc ttcgtggata ttctcttgga tactttaaac atggacctac
5461 gttccgctct cgaaaagacc aatataataa aaagttataa attacatttc cttattaggt
5521 atacgacctc gcgcttcgaa gtagaggagc cctttttggc gtacctacat atggcgcgtc
5581 agacagacaa acttccccca aaaatgtatt accccgccga ataagaaaac agacccattc
5641 acccacgacg tatcaagtta cttccttggt gcaatgtccc actataaaaa aattccttga
5701 cgctagatcg ttggactaaa atctgcgtca caatcgccta aacaggaaat attgcctatt
5761 ttcgtacaag gttacttcct agatgctata tgtccctacg gccttgtcta acaccatcca
5821 gcatgcaata cagtgacata tatatatacc ctaacactac cctaacccta ccctatttca
5881 acccttccaa cctgtctctc aacttaccct cacattaccc tacctctcca cttgttaccc
5941 tgtcccattc aaccatacca ctcccaacca ccatccatcc ctctacttac taccaccaat
6001 caaccgtcca ccataaccgt taccctccaa ttagccatat tcaacttcac taccacttac
6061 cctgccatta ctctaccatc caccatctgc tactcaccat actgttgttc taccctccat
6121 attgaaacgt taacaaatga tcgtaaataa tacacatata cttaccctac cactttatac
6181 caccacacat cacatgccat actcaccttc acttgtatac tgatatgcca tacgcacacg
6241 gatgctacag tatataccac tctcaaactt accctactct cacattctac tccactccat
6301 gacccatctc tcactaaatc agtactaaat gcacccacat cattatgcac ggcacttgcc
6361 tcagcggtct ataccctgag ccatttaccc ataactccca cgattatcca cattttaata
6421 tctatatctc attcggcggg cccaaatatt gtataactgc tcttaataca tacgttatac
6481 cacttttgca ccatatacta accactcaaa ttatatacac ttatgccaat ataaccaaaa
6541 aattaccact aaaatcacct aaacataaaa attatttatc tttcaacttt acgaaataaa
6601 cacactcaat tgcgtatcta taccaccatg acgtcattaa cgtaaaagtt ccttaatatt
6661 accatttgct tgaacggata ccatttcaga atatttctaa ctttcacaga ccatacatta
6721 gaataatatg ccacctcact gtcgtaacac tctatattca ccgagaaaca atacggtagt
6781 ggctcaaact catgccggtg ctatgataca attgtatcct atttccattc tcatatgcta
6841 tccgcaatat cctaaaagca taactgatgc atctttaatc ttgtatgtga cactactcat
6901 acgaagagac tatatctaaa gaagacgata cagtgatatg tacgttgttt ttgtagaatt
6961 ataatgaaac gtcaaataac cctactatat tataacttat cagcgccgta tactaaaacg
7021 gacgttacga tattgtctca cttcatctta ccaccctcta tcttattgtt gataaaacac
7081 taacccctca gctttatttc tagttacagt tacaacaaac tatcccaaac cataaatctt
7141 aatattttag gtgtcaaaaa atgaggatct ccaaatgaga gtttggtacc atgacttgta
7201 actccactac cctgatctgc aatcttgttc ttagaagtga cgcatactct atatggcccg
7261 acgcgacgcg ccaaaaaatg aaaaaagaag cagcgactca tttttatgga aggacaaagt
7321 gctgcgaagt catacgcttc caatttcatt attgtttatt ggacatactc tgttagcttt
7381 attaccgtcc acgctttttc tacaatagtg taaaagtttc tttcttatgt tcatcgtatt
7441 cataaaatgc ttcacgaaca ccgtcattga tcaaataggt ttataatatt aatatacatt
7501 tatataatcg gcggtattta tatcatcaaa aaaagtagtt ttttatttta ttttttcatt
7561 acttttcact gtctatggat tttcattcgt aaaggcatca ctccctagtt tgcgatagtg
7621 tagataccgt ccttggatag agcactggag atggctggct ttaatctgct ggagtaccat
7681 ggaacaccgg tgatcattct ggtcacttgg tctggggcaa taccagtcaa catggtggtg
7741 aagtcaccgt agttgaaaac ggcttcagca acttcgactg ggtaggtttc agttgggtgg
7801 gcggcttgga acatgtagta ttgggccaag tgagctctga tatcagagac gtagacaccc
7861 aattccacca agttgactct ttcgtcagat tgagctagag tggtggttgc agaaagcagt
7921 agcagcgatg gcagcgacac cagcagcgat tgaagttaat ttgaccattg tatttgtttt
7981 gtttgttagt gctgatgtaa tcttaacaag aaatagtgaa atgaaagcgc atacctcaaa
8041 ggcatatagt tgaagcagct ctatttatac ccgttcctcc atctgtcatc actacttaaa
8101 cgattcgtta acagacgctc atttagcacc tcacatattc tccatatctc atctttcaca
8161 caatctcatt atctctatgg agatgctctt gtttctgaac gaatcataca tctttcatag
8221 gtttcgtatg tggagtattg ttttatggca ctcatgtgta ttcgtatgcg cagaatgtgg
8281 gaatgcctat tataggggtg ccggggggtg ccttgaaaaa cccttttgcg cgcctgttaa
8341 gtttccgttt tcagtcaaaa agaatatccg aattttagat ttggaccctc gttcagaagc
8401 ttactgtcta agccatcatt tggtgtgtcc taaacggttt ccatgcaaag caacatcttt
8461 gttactcatt cctgaaggtt gaataaaaaa tagcaaccat gtgcagggag tcgtatattg
8521 ttagattcta gagacttgta cgcatcatca aagctgtaaa tagaataaac atacgcaagg
8581 cgtcaaaagt gcatagttaa gaaaattcct gacatgtgaa aatatgtgtt tatgaaatgt
8641 gtcaaggccc gtctatagcg tagttaaccc ctctgcagga gtaagtgact ttttttacgc
8701 tcaaaaggca acgagggcac atacttaaaa gtcattttca aacacatctg cagtttgcaa
8761 cgacagataa caatattatg ataggatggt atgatgttat tagctgccac atatttttta
8821 acatagcatt agtcacgtct cttcaattgt tgggatgaaa ctctaaaata tcattccttt
8881 agtagtattc cagttaccag tatattatca catgccgaaa aagaagatga cataaagatc
8941 gacaaacagt cttcaaatat aatggaagct ggaatgcaag gattgataat gtaacaggat
9001 actgaatgac aaagtataaa tgaaaaaaaa aaaaaaaaaa aagtagtaat actattatgt
9061 ggaaataccg attccatttt gaggattcca attgttggaa taaaaatcaa ctatcatcta
9121 ctaactagta tttacgttac tagtatatta tcatatacgg tgttagaaga tgacgcaaat
9181 gatgagaaat agtcatctaa attagtggaa gctgaaacgc aaggattgat aatgtaatag
9241 gatcaatgaa tattaacata taaaacgatg ataataatat ttatagaatt gtgtagaatt
9301 gcagattccc ttttatggat tcctaaatcc tggaggagaa cttctagtat atctacatac
9361 ctaatattat agccttaatc acaatggaat cccaacaatt acatcaaaat ccacattctc
9421 tacaccaata ccatcgacga gagcttctag taaattgtat acataacagt ataaccctta
9481 ccaacaatgg aatctcaaag attattaaat tattcacaga ctctgaggat tcgggtaaaa
9541 tagggtattt aactggttac cggaaaggtt tagaaaattc gtggagggtt ggccgagtgg
9601 tctaaggcgg cagacttaag atctgttgga cggttgtccg cgcgagttcg aacctcgcat
9661 ccttcagtat tttttttgat gatttaacgt actattaact agaataatag ggaaatgcaa
9721 ttgcagtttg agaagaagaa ttattaataa gccaaaaagc ggctcactaa gtaagttttt
9781 cttcatggcg tcctttgcat ccagcaataa tggttttagc aaaaaaatct ctttcactac
9841 acaagttgga gcatattttt taacaaatac agataaacga aaggcgataa taagtatact
9901 tcctatgtac aagaatcttt aagtgatata atctttcagc ggactagaag aatagggcgt
9961 tcaactgttg tccttgcaga attgcgtaaa ctccttcaag tagtcattat tttgctcgca
10021 gttttgcctt aaaatgccct ctgttgtaga agttaaaatt tgttctattt ttctattatt
10081 tgccacccac tctgtcacct tcgtccaatc cttatattga gcttcctgtt tctccgctct
10141 ttctcttgca gcgtaaggat caattcttgc gtctataagt ggttccgcag tagtcttttt
10201 attattaccg cactgctgat cggtctcgtt cttcatctct gctgcctctt tttcgcaaaa
10261 tgaaattata ttattccgta tttgccagtt cggatatagt tcttgcttca aaaattcctt
10321 acacttattt tttccattaa tagagccttt cctatagttg tttaattttt gtcttattat
10381 atcatcactt ccatgcctta gaaacctcaa aaatgaatct atcaagcttg gatcaacaca
10441 tctttctcgc gtaactgtga ttgtagtaag tgacggttca tcattcggaa aagtaagatt
10501 tgtttcaagt aagctttggg gtgccgtaaa cgtacgccta ttatcaacca taccgtcttt
10561 ttgtctacgt gtataaatga gaagtttttt ttctaactat atccaagttt ttcaaactac
10621 ccaaaggata tttaacttgg cggacaaaat taccgtcacg ttcaaaagtg aatatatagg
10681 cgattctggg taacaagcaa aagtaaacta caatatggaa tagtgtaaaa cttcacttat
10741 caacaacaaa atcgcttcaa gcctcctatc ttagagtcta gagcctgata aaattcttat
10801 gcgagcaagg gcaacctgat cgaattttat aaaaactatt tatggactaa aaacctacag
10861 cgctcttcat catatccctt cccgtttctt ccattgcgtc attcatggtt tgtcccattg
10921 tggttgcata gtcattaata gtggtttcta ccgtgtctaa acgagtttca attgccctag
10981 aaacactttt aaggacacca tatccattac ttcttccaga gcttcttaca ggtctggcat
11041 acctgtgatc ttccgtaccg ggaggtaact ttctggctgc attactacta ctggaagata
11101 tgcatcctcg agcaattgcg ctttcctcat acttcgattc gggcctttct ataccgccca
11161 gtagctcatc aagttgatat ggtgtgcaat aaatagttcc tctagcccat tgtaaggaat
11221 tcacttgagg cctataacca atctttaaat caggattgta caaggtatca ataggagtat
11281 gttgtgatat gtcagcagta tgattcgttc cggtggcact ttcattaagt actgaaatca
11341 aagaggcttg gaatttccct gtgcgaatga caatgtcacc attttctaat atagatgaat
11401 tttcaacgta ttgagcgctt agagggaccg ggcagcgtag atttttgact tccttaagct
11461 caggtactgt caaaacttta atatctccat taattagcaa aacgatcata atagttgaaa
11521 gctttctttc tcctttaccg tcaataatgg gaataaatga taatccacta gtggcaattg
11581 gatacttgaa aagcgcatga gtgtccttag atttacctgg tgatactaaa cgaatgtcat
11641 ttgcgccact gatagtaaca aatccaggta ttgcgatacc cttgcttaaa ccctgcatct
11701 ttgatatagt agcagaacaa ctgtagccag tatctttggc aaaagaattt attcctagaa
11761 tttttccttg attgttggtc tttgttgcat cagtgaattt aacctcaaat cttccattag
11821 ttgcaggcag tattttgaaa gtcatcaatt ccccgatatc cgttccacat agcatcaaaa
11881 tactagagaa cccatcatct ccatattcca tgacgcaaaa gtgaacggtt gaaacgtaag
11941 agctaccagc tttagaaatg accctaatat tttcattgaa gattatagcc gggcctcttc
12001 tgtccaatat tattaaggtt ccttcaatga aaccaacggc aacgaacccg atattactat
12061 tcatgattgc ggacaccgca ccttttttag catgtattac cgtacttggt ataaagcctt
12121 gtttaacgtt cgtaggccct ctatccgaaa catcaactaa aatagttttt gaatcatcca
12181 atgaaaatct gctaaacttc aattgcagtg catcgctttt gggaagttgt ccgtaaaact
12241 tgtttgtttc gaatttgaaa agaataacat ccccaacctc agatgatacc gccaattcca
12301 atgtttccga tgcaaaggag atatttttta tggccaggtt agtagctctg ttaagtactt
12361 tagcagtatt cacttcaaat acagcgttgt cagttacttc actgtgtgaa gcatcccata
12421 ttctgactga accattacta tgcccagtta gtaaagcaga tctggtctca tgccttctaa
12481 tatttctggt ggcaggaata ccacctttta aaaacgattc actttgagcg attgtcatca
12541 tccccagcca aagatttttt tgaactgatt gcgctataca agtagtaacc gttggtcgaa
12601 cccatgctaa gctccgaggg aaaatggagg ccttggaact aaaagagcct gctgggtata
12661 tcaatgtttc aagttcgcca tcttctaaaa gtaataaaat gaggtttgtg tcatggcatc
12721 caccaaaata tggagaagcc ttcggcaagg gtagaaaatt tattagtgga gctttgccaa
12781 tcaacgaaaa tagtttttgt tgaaccggtt tagcatagta cttgctcatt gcgtcaaatg
12841 atgtcacaga atacattggt gtgccgccta agtcaatcat ggttatttcc tgaggtaaac
12901 agggattttc tgtagctttt gttgcaatca acaacgatgt atactcagga ttacgctggc
12961 aaagccagct tactttaaag atagcgggtg tttctgtaaa ggaacagtct ttcaaggcag
13021 gatttggaaa attcacatgt gtttcaaata tacttctagc gtgaatcagt ttaccgctat
13081 tgacatccca aaataccaag gaattatctt catggacagt taatatatgt aaggaatttg
13141 ggtgataaag tgactgaatg acctttggag tgcgtttctt ttctatgttt gtggatagat
13201 caccgcccgg agcatacggt tctaattggt aaaaaaaatg ttgcttgact ttgtagtcaa
13261 tgaaagaata tatgactgta atatgctcat atgatataag tatcgttcct atgtctctag
13321 gattccattg gatagaaata accggtgata gcctctcttt tggcaaaaac acacttttct
13381 ggaagttttc aattttcaat ttggacattt gatttctatc cacatcatag atcaatatgg
13441 atccactctc gaggccaatc agcatccaat ccaaggacgg atcagtctca atacaagtga
13501 tgctgtttgg acagaaaaca gtagttagaa tctgtttcga gtgtactgaa agaactatta
13561 tgttgctctt ctcatctaca gctatcagat aaattccttt aataaaccgc atgtgtttaa
13621 tttgaggtcg attttttaac gtaaatacga cctctatttg cttttgccca taaacatgta
13681 tctccccagc agtagttgca actgccaaaa ggctttgagt atagtcgaat gtggtaacag
13741 tgattcgtcc atttatgccg tatgtgcata ttttcttagt atcgaaaaat ttggagttaa
13801 taccatttga gacgtcatga actctcgcgg atttgatagc atttgacaca ttcttcaaat
13861 gcctgctttt cttaaacatt tataaaattt ttgtatctgt tcaattgaca attttgtaac
13921 ttttataatc tgtcaacttt agaaatatgt tagtagtaat ataatactga gctgtttctt
13981 aaatgcttcc ttaataatgt aaacagaatg cgcattgttg aacatacggc ttcgcatcgc
14041 atcgcttaaa cgaggttttt catatgcatg ctccaagata ggtacgaaca aaaaagaggc
14101 attgcatcaa aatggatagt ttcagtttat gtaacaaaat ctcattaaaa aaaccctctc
14161 ctcctatgaa gcggaacagt tcaacttttc cgcttagatg ttttatataa aattaaataa
14221 atcatggcat gaccttttct tcataaatcc aaatcatctg gcataaagga aaatcctcta
14281 aactcttctt gctggctcgt tgtcaaaaca gagggcagag gtgtaagtgt gggtggcgca
14341 gaggtgaatt cttgctcgaa atatgatgta tcttccggag atttaatttc tgggatgtag
14401 ggtggtttca cgcgaaggtt taagatatcg tcaaagttga tgttacggaa gaaaggttct
14461 tccataactt cgtctgcgtc cctgggacca gcacccaacc tcttttcagg atcttttgtt
14521 aataggcctt ggaatatttg tacaatctca cctgccatat ctattgggta taagggttca
14581 tcggtaagga tagcgttaaa aacttcatct tcgtcatctc ctgagaatgg agattggcac
14641 agtagcattt gatatagcag caccccaaat gcccaccaat cgacagcttt ggtatattct
14701 tgctctttta aaatttctgg agccataaat tctggtgtgc cacaaaatgt agaagttcta
14761 ttaccatacc acatttcatc tttacacaaa ccataatcgg caatttttat atgaccttct
14821 ggagttaata gaatgttttc caacttcaaa tcacggtata ttacaccatt atcatgaaaa
14881 tatttcagag ccagtaagac ctcggcggca taaaatttgg cccttcttac agatagtctt
14941 tggttttgaa catgccacat taagtcaccg cccccaataa actccatagc aaaatatata
15001 cggttttcag tttgaaaaga gcagtataga ttggttaaga atgggtgttt agtttttgtg
15061 gctaacaaaa atactttctt ttctgctctt gcactctcga tgtcatgatt ttgaataata
15121 ttatctttct tcagaacttt tatggcacaa agcctgtcag tattctttga tttagataaa
15181 ataactttac caaaattacc tttaccaaga actttgagta atacgaaatt atctaatgaa
15241 accttacgac gtttagccgc tctcttttta tgctttgcgc ttgtgctggt ttgtgatttc
15301 tgcggagatt gttgatcagt ggttctggag gcatgagtac ttgtaggagc caaggacact
15361 gtttcttgta gtacttcctt tgaagcatgg tcttgttcaa tttgaaaggt ttcactattc
15421 atatcgcgga atggatttgt gtgtgtggaa tctattgtca aatcagcttc acggaaatca
15481 tttttgttct cccagtctag tttctgtttg gtctctaaat caatgtgatc aacttctaga
15541 tcctcttgga tttccccact atcttgtttt atttcaagtt ccatttcctc acgttgtgct
15601 ttccacagtt caagttcatc tctcattaaa tcatctttag attcccaagt ttgactatgc
15661 tcaatagata aatcagtgag tcccaaggaa cgtctattcg acgttggatc cagtgttttc
15721 tctggtgatg aaaattcggc ggtttgttgt gcaccttctg taaaatttaa ataggcctca
15781 ttttcatcga taaatttatt tagtttctca cgcccgtgcg tttgtagtga aattctttta
15841 tcaataatag gatcatgctg cttagttgga gaatctcttc ctaccttctg aggcgaagga
15901 gttttatcat gttttcttgg ctgaggaggc aaaggagcgt ttgccctttc agctaatttg
15961 gatggggaaa gatcactacc attggcagta ccaatagatg accccaactg tgccgacgga
16021 actgtcctct tctttttctc ttgattacgt tttgtgtctt gaatcgtttt cagaatttta
16081 ttagccattt ccatcgacat gccacagaaa tcgggaacca aatgagcaca ttgagcatga
16141 cacattatac cacattcaga acatttgcgt actttatgtc taccccatgg taaaatataa
16201 ccacagtgac agcaccattt agtaccacgg tttgaagtag gcaggaatct atgaggaata
16261 cggtggttca actttgcctc gtccggatcc gtatcagtag aagttttagc aatacactta
16321 gtaacaacat tggtgtaaca ttttttgtga cataaaaatt tacaatcttg acattggaac
16381 ccagtatacc gaaggaaatc accacaatat gcacagcaca taatgttgta aaatgatttt
16441 tgtacaaagt ggtggccatg ctgttcgaat atctcttctt tcctattgat aatagcacca
16501 tgacgatgta gtccacccat caactgcttc ctttctattt gagaagactt gtggaatcct
16561 agtgttaaca aaatctgccc ggatggttct aagacaaacc atgaattcgt actgatttga
16621 ctagttgatg tattttcgcc ttgcacattc tttgctgaag tagactgaat ggctgagttt
16681 gagtatgtag aagtcaatgt gcttccctct tcgctagcga gagaagaacc accattaatg
16741 tttgaagcgt tgacccatcc ttgttgttca tttgtttgtc cggctttctt cttacgaatt
16801 tcttcagcga tatcggaaag cagtaaccac attatagcca ctggaatgag cgagtcgttc
16861 accttatcat atacagtaat ctcgatttca ttcccttttt caactggaat ttgaaaatct
16921 tcactccacc tgtcatttct agaaggcttc gttctggctt tgatcgtatc atcgattttt
16981 atagtaacgt agctctctgg cttcctggca aacatcggtg attgtatatg gtcaacatct
17041 ctagcagcag ttattccaat tgttagaacg ccagtcagtt gttttcttcg gaatttcggt
17101 tgttgattat ccattatgtc attgggttgg tgtttaaatt gatcaaagtc aacgttaata
17161 gcttggtatt tcttcaaagc tttgttaagc atttgaatcc tgtatttgga ttccatagca
17221 cccccttctg ccgcagaact actacgttga tcaccgtcaa tttgatacaa tttagtcaat
17281 ttagtattgg cttcttggta ttgcttttcc acctgtaatt tgaattctaa ttgttgcaac
17341 atgtattgga ttctttgcgc caaagaaggg caatcatatt ttactaaatc caaacgagaa
17401 aatatgtgtt catttggcga tttggtagaa agaaacccgt attccttcga attgcatcgc
17461 tcattatctt cgctgccatt ttcaccctga ctttgttgag cggtcttcaa ccgtaatttt
17521 tttaagctat cctccaagta ctcaagattt tgacgtgcct ctctaatatt cgtattacat
17581 ttctgaatga ccataacatt gctagtcttt ttcttgaggg cagaagctcc ccgaataata
17641 ttttcttcga cggctatctt ttttttaatg ttctgctcca attgtgaaaa actcatgact
17701 gtaaactgct ccctatatgt gtgatactat acttactttt cctcgctaga gcttctctcc
17761 gcagctactg ttctaggttt tattcctatt gattatctaa tatagtttta aaaatctata
17821 ctgaaagggg atcgacgctg aatacctcta acgtaagtgt ggacgagtgg tggcagagac
17881 ttttacaatg gttaataatc agtctctact cagccaaatt gaatagcagt gaaatcgtag
17941 ctcttttact gctcctgaac ctgtcgtatt actttcgata gagtagatca actttattat
18001 ccacgcttgt taactctttt cgtcggtttt tttcgccttt aaaactaggc gggctgggta
18061 atgaagatag caatgcctca taaatacaat gttatactaa ttacgttttt tctttggtta
18121 tgtatatata ttgtgagaat aaagagaagt tgcaagattt ggtttattgt acaatactac
18181 ttattacact ggcaggtgca acctggagtg ggacaaacat tatgtctgtc aaaccattct
18241 tcagcgtgac cggcatgcat accatggttg caactcaaac agaagctgaa ccactcgttc
18301 aacttcagtt ttctacttac gagttcgcga tttgcaccat cttgagagtc ttctgtctgc
18361 attggatcgc gtgattgcgt cccatttatt acaaaaggta agtttgacgt tcctagaggc
18421 atgagacata tggcacatct tggaaatgaa gacccacagt gtgggcaaca atacttatgt
18481 cttggctttt catcagctgc ttgtgcttca gaacttccag tattaaattt cttgtagtca
18541 gcgttatttc ttctataggc ttcaccattt ttgtaatttc cagcactagt agagacggcg
18601 ctagaaggtg aggatgtgcg cggagtgttg atgttttgtt tacagttttg acattggata
18661 tatatttgcc ggggctttat gtctgcagtt aatacaccag ttttagttct cgataatttt
18721 gatcttaaaa catcgaacct ggctcgcatg gagaataatt cccacgattt aagcatatct
18781 ctataagttt gtatccattc atctactcgt tggtcgcgga aatatctagg ggagccgaaa
18841 attgatatca gtgcggcact ctgaacatcg ctggttttat taacgtatga ttgcagtaga
18901 tcgataccat taggtgttat tccggtgaga attaaacctt ctaattcgcc gttttcaata
18961 actgtagatg aagttctatc taagaaagtg gttaggtctg tatcattcaa aaaccttaga
19021 gctaccccta atcgttctct caaagatatg gcaggttcat aaagaatatc ccaccaatca
19081 ttgtctgcga taaaggcgaa aataactctc aagtaaggat catctaattc ggaggacatt
19141 tttctgcatt gctgcctcca tgcattgtta cctggcagat ccttatacgc caagtaacct
19201 gcaatagcgg tggcaattag tctcaatctt tccttttttg cagatcccaa tatttctaca
19261 gcctttggga tatcaccaaa aaataccgcc caagcggcag ctttttcata atggccgttt
19321 ttcataatta tgttgtactt gtcttcataa tcagatctgg aaaggtccca tcctgagata
19381 attaaacaga gtcttctctg aacgtacttt ggtgaaccag cggcattggc aataggactg
19441 ttccgatccc tatttttcct tcttagtttg atgatttttt ccatttcttt atttagttgt
19501 ttatcagaaa gaattgtctc ttgtctatat ctgtcttggt tcgatattcc gtttatacca
19561 ttccaaatac ctatcacacc ttcgtaacct aagtcaagat caccagaaac catcgtacca
19621 tcgtcaacag aagcctttgc aatcgcgatc cacctccatg tgttccttat ataagcattg
19681 ttttgtagat ttttagaaga atcaatcatc tctaccgtgt tcattggatc caaaccatat
19741 cccaatgaag ctcgcgtcct cattattaca cttatatctt tttccagaag tttttctggc
19801 ttccagaaca gttcaaatcc acgcttactg tcaaggacat cattactccc ttcattttcc
19861 tcttcactca actcggagta ctcaatttca ttattaggtt catcatgtcc agacggaaag
19921 taatcttcgc taacatctaa atcctcaaac gatagattct ttaggattgt ttttacattc
19981 tctaagttgg acttttcatg ctcattgttg actctaattt catctatctc agtattttca
20041 aaatttgaca ataagagaga gttcctatta ttgagtatag ccttggagca tacctctgaa
20101 attggcattc tgtatattgt tcccgattgt ctcatacaga ttagacttgt tccattatta
20161 cttcttggaa tataatcaaa tgtagcaact ctatcgtaca tcgtatttgt gtcatgcacg
20221 gaagaaacaa acaaattctc aatattcatc tcgttatcgt catctgccgc aatatcacga
20281 ttgctatcgc agtaatagcc taacctccat cttttgatgg tatcacctct atgtaaggtg
20341 gcaaattcat tgttcctcac acatgaccac ctaaagcaag agttcatgta tttccttgac
20401 gctgcaccgg atccaaccaa tttttcaaaa gttaataaag gggaagctac atttaaatca
20461 ccaagtgaag cttggtcaga taattttctc ctatcccaaa tagctaaggt cccatcatcc
20521 ccataagtac taaattgcca atcgttaaac gggttcagtt tgatatcata cgtcaatcgt
20581 gtcggatgtt gataaattgg gttgggggat ctgacgtcaa tttctttcaa aaatttcgta
20641 cttgcagcca atacactggt atcgttgagg aactttaggg atactatgct ttcatttgtg
20701 caataactaa acattgggtt gatagtttca tgcgaatcat catgataatt catgtcccaa
20761 atttgtaaag atgaatcatg cttatttctg tcaagaccca ttgctataag accattcgta
20821 tttattccca gagagtttat acaccgctgc ttctttgctc gtacacgtat atcataattg
20881 gtttctgaaa cagggtaccc ttgggtatcc tttaaatttg agacagatcc aactatattt
20941 tccgcctgag ctgccttacc accgctggca tttgtcatag aagtctcgtt attggcattt
21001 aagcccactg gcgcatggct cgctggcgat gaggaatttt gtccagagat attaaaaatc
21061 cttaaatatc cattcttttc accaactcca atcataccaa tttctgattc tgaatagtct
21121 aagcaggtga tactgccgaa gtctttcaca gtgtgtaatt taataattga ttcatcagat
21181 tcattttccg gatccacttt atagtgggtc acttcatctc ttgtagggtt cactgaaaga
21241 taatcaatca aattatcata tgaccaatgg gtcacttttt tgatgagacc catgtttatt
21301 cttctatacg ttcgtgatac tgcacttacg actaccagta acatcagaat aaccatagag
21361 cttatgctat cttgaaatat atcatcgccg taaagtatga tgtgtagcgc attagtcttc
21421 tgcattcata ttatcagtgg tataccgttt ggtatatgct ttccaatcat gaagtgttgg
21481 ctctactcta tataaattcg acatccattg attttctcaa taaatgagtt acccaagtaa
21541 gctttccatt gatacaagtg atctacattc ttgcgacgcc aaattataaa gcactaaaaa
21601 tcatatcata cccaattgcg ggcagcacat gtatatatta tacactactt ataactaacc
21661 ttcttcatat ataacaatat gcctgataat actaatgcat ttaaatcata tcatgaaaga
21721 aaattacatg ggttttattg acataattgc atttagaata cataaaattc taaagaatta
21781 atatatccaa agtattagac ataaccaaga ataatagtga ataattttag attttgttac
21841 atataattct gcttgcctat ctcttccact cttttcaaaa cgttgcatgt aagcgttact
21901 aatattccgc tttattttgt tgcaattcct aattttttca ttacattatc ttgcgagtac
21961 ggaagcgatt aacgttctcc caatagaagg aacaaacata gatattgaag ttttactgct
22021 tttgcttacc tgaccttttt caaatttaat tttttcccgc taataagacc ataaactacc
22081 ccgaaccaaa ttctaaaaga tagtcagctg gattagagtt gtcatctcca aacattaatt
22141 ttgcattatc ttcggcttca atcaaatcgc ctgataagaa ctcctttaat tcttcatgaa
22201 tgtttgtatg tggatgactc tccatagtgc cagcatgatt gtggttaccg accgaatcat
22261 ataacggtgg ctcccaattg tgcaattcag ccttactatt ttgttcattc atcaaagcat
22321 ttgggacaga tctaatatct ataattcttt cctcactatt ctcgctatta ttttgccccg
22381 aactggcatg gtggttattg gtaaaaggag ataatgctgc gacagaactt ttcttctctt
22441 ccaattcttt tatcttcgcc aataacgcct tcttttttcg tgcttgtatt tctaaaattt
22501 cggccaggta ttgtaaatat tcgaccgttc tatccaaaat gataccctta tttggtttga
22561 tttgtttacc taggtcatcg taattcaata aagatggtgg aaccaactgg ccgagttctt
22621 ttatcttttg ctttattaat tctcttcttc tcctttcgac ggcattatga aactctcttt
22681 tgcgcctcag tttctcatca gaagttaacc cgcctaaaat ctttggaaca cttccaggtc
22741 ctatattttc agtcatattg ctacttattg aagtgtgtct tgttctgggt gtgtttatgc
22801 taccatgcct aaaagaagat gaaaggaaac ttcctgcacg aaatgacgat gatggtgatc
22861 ttacctttgg ggaatatgtg gaagatacgg atgctgggcc caagctttgt ggattataag
22921 aaaatgatga tgaatatgtg tttggtgtca tcatatcaga attgatgcta gaagataaag
22981 aggagctcaa atcatcagtt aagttataca ttgtgtcatc ggtgccatgc tgaaataaaa
23041 agtcatgtgg taactcagct tttaagcctt cttgttgctg taatggagta ttcattgctc
23101 tatccacagg tgagtcgtaa gccatagaat aagatgatct caagggaccc tgccctatgg
23161 aagatatgga attttgagtg acaggtctac cgccttggct tgttctaaac atatcatcca
23221 ggtaagacga ttgcgattct gcttcctcat atatggtcga agctgtagga gtttgtgaat
23281 tggacctcgc ttgactgccc attaagttat tattatcgtt agagttgtgc gtattgatgt
23341 atgagagttt ttcatgctgt tgggcaggag tctcaccacc tgggtaggca cttccgtgta
23401 tcttgtaatc atcattgtgg tgtggagtgg gtgtcactaa cgaaaaatct aaagtttcct
23461 ggaggacttt tgtctggttc attaattcgt ccagtagacg ttggttctca gcctcacttt
23521 cgttattgtt catcattctt cacttattta agaagtaggt tcgcctgaca aaaaataaga
23581 gtattctatt aaaggatact tgtcaactaa gtaatgtgaa tgcagtaatg tcgtttttgt
23641 tatcttatat atgctcacgt aagacagaaa ttcggattgt gaaaaattcc ttgatgattc
23701 cgtgcagcct ctagccaaaa tagcaactgc gagtaaaaaa taatgtacta acctgcagta
23761 atattggaga tcctactgtc cggaccgagt agtacaattg ttagtttctg ttgctcataa
23821 gaaggctttt ctaatcacca tggctttatt atttcaaaag taacttgcga agagtcacat
23881 cccgcggaac ggcccgcaat cgtgacccgg caaaaggcga ttgtaatgaa gagggagtat
23941 tggtcaagac ttgtactata ctgaaatagg aagaagattg aataaatttg cattctaatt
24001 gcgttcggta gtttagagta ggacttagat tacctgtatt gtctgcagtt gcgttttttt
24061 tttttgctgg taaaaaaaaa gaacaagtgt ggagaatatg agcgaggaac caccttctga
24121 ccaggtcaat agtctccgtg actcattgaa tcgatggaat caaacaagac agcagaactc
24181 gcagggtttt aatgaatctg cgaagacatt gttctcaagc tgggcggatt ctctcaatac
24241 cagggcccag gatatatatc agacgttgcc tgtatctaga caggacttgg tgcaagacca
24301 ggagccgtcg tggttccaat tgtcaagaac ggaaagaatg gtactttttg tctgttttct
24361 tttgggtgca acagcctgtt tcactctttg tactttcctt ttccccgttc tagccgctaa
24421 accaagaaag tttggtttac tatggacaat ggggtcccta ctatttgttc ttgcgtttgg
24481 ggtacttatg ggaccactcg cgtacttaaa acatttgact gcaagggaaa ggctgccttt
24541 ttcgatgttc tttttcgcca catgcttcat gacgatttat ttcgcagcct tttccaagaa
24601 cacggtgctg actattacat gtgctcttct tgaattagtt gccgtcattt attatgctat
24661 ttcatatttc ccattcggtg caacaggttt gaggatgtta agctctgctg gtgtcaattc
24721 ggcaagaggt gttctgcgca tctgaattat cattcatagt gcatattgaa ttgattagtt
24781 gaagaagaaa aataatgttt atgttataag aaacaataat aaagagattt ataacctaac
24841 ctaattaaat agcatgtagt caacaaaaag ggagtaaaac atgcagtggc tctatatata
24901 taattatcgt agaataattc aaaaaaaaat aaaaaacgaa aaaattcatt cttcatcact
24961 catcaaaggc actatttcgt cataacgcgg aggctcgtta ccatgagaga gtagcgaatc
25021 tgcggagctc gaacttacta ttccttcttg ttcttcatca tcttttacat tcgctaaagt
25081 gtaacccttt ttgaaaaatt cgttctgttt gtccttagag ttttcagtgg tagcgtttgg
25141 aatcctcaca gtaccatttg cttgtgataa gccatttgtt ggtgatgaat tgtgagatct
25201 attgacgggc gatggagtgc tcaataattt atcgagatta ttgaatcttg acctgtcatt
25261 cactgacgtt gctcttgctc tagcaacacc ttggccacta ttgcccgaaa caaatgcgga
25321 attcgaaata ctgccgttca tggcattggc atttgaaata ctgttccgat taacatttgg
25381 cacaccggca tcatcgctgt atccggatgg cccactaact gacgtagttc ttgataagtt
25441 caattgttga atagatagta aatcagggtc atacgaggcc atgatattag gtgatcccat
25501 cggtgagaca atgggagaag ctggaacgga tatggcttct tcaaaagttg gcggaggtgg
25561 acatgtgtta ccaaaaaagt cgctgttcat acttagagga acctggttgc ctttgccttc
25621 cattgtggcc atatcataag tgggtaactc catattacca ctgttgcact gttcagacac
25681 caggaatatg ggcgtatcga ttagaacctc ataatgtctt aatttggacg gacactcagg
25741 atcaggttta ctgattcgta gcataatttc cagcttatgt ctacagtaaa cattactgaa
25801 gtgtaaacta tccaagtaca agcctctttt cggtgtgttt aatctggtat gtgttttcac
25861 gggcaaacca gaattggatt tgattattgt ttgatggaat tttggatcat aaacaggttt
25921 ttcattttct tcatgacttt tcgagccttt atgaccggat aaaaagccta ttacactggg
25981 acgacggtgt gagggtccat tggctacggc atgttcggga ttggggatgc tcgtgtatgc
26041 atcgatacca taaggtggta ttatctttgc ggttctttta tccaaatctt cgtatttggg
26101 gaacttcaat tttgtttcaa taattattgg ttccgttata ccgagccttt ctttcggatt
26161 gccttttgaa tcgctgtcgt catcaaaagg actataagat aagagattgt cattgaatga
26221 attttcaaca atttcctccc ttagagctct cgtgcccttc tccttagttc tgatttcaaa
26281 taatgataca cttctttcct ttcttctctt ggaggcgaaa tctaaataat acggattata
26341 agggtcttta gcaacgggat ctgtttgatc atactcatat tcataacctt tactaacaaa
26401 tgtgactctt tcagtaatac tgacatgaat acgtttaaca caaacgtttt tgcatatcgg
26461 tgccaatttt atcttgattg ggacttcact gtttagtgaa acgtatttct gagcaaagga
26521 aatctcgtat gacaaagaat ctgtccaaac cctattaata tagattggtt tattcgcagt
26581 ggatacggca acgggcggtg gagttctaat aacttttatt ggatactctg cgaaaatgtc
26641 ctcttctcct gattcttcat ttttcagttg atgtgagctc atgtgtagat gatttttaac
26701 tttactaaac aaagtgttgc ttatcctcct atgggcctga gcggattctg tttcggtaag
26761 ttttaatgaa gatgtagtgg agcttagtga tgaagaagag tctggcgaca caataggttg
26821 cggagagttt gaatcttgac gatagaaacc ctttctattg attgcctttg ttgcaagcct
26881 tagtctgtaa ctaacacgtg cagagggtaa atagatagtc tccggaatat gattagagaa
26941 aaccactggt actaagaata catagtctcc aggttggtaa agatgagtct tatttacgtc
27001 tatggcgttt aaaaggctgg cttttgtttt agtcttgtcc aaatacagtc tctcctctgt
27061 aggaatattc ttgaacaacc tcatttgacg atcgttggag ttgttttcaa tcatttgatc
27121 atctggggat atgcttaatg gtacaaacaa atcgaagttt tcatcattca aattccattt
27181 cattgatgca gcattataaa attcttcatt aaacgtcttt gtaggaggaa cacctgtatt
27241 ccaaaacact ttaacccttg aacataattc caattgcatg tccgtaaatc gggttggttt
27301 tttaacggat actataactg ctatgctgta agagaccatg gaactgtcga tttcaacaga
27361 ccttgtatta agttccgagc cggagcctgg atggtctcct gaattatttt ctctcaggag
27421 tgtgtctcta ttttcattta tgctgccacc actttcggta gccgctgccg ttgtagcgag
27481 agatggagtg ttaccttctt gctggtctat accatccata aaaaaatccg cctcagcatc
27541 gtccgtacca tcattgagtc cgtttagtct ggacaggtac tcatcgtcat tcgaggatat
27601 cgttggtaag aaaacgcttt caccgcttgt agaaatagaa atcttcaagt actcattgga
27661 tagaacggtt tttgggccca ggagacctct agcggttaaa tattctatga gaaattgctc
27721 gttaaacttt ttcgagtttg ccaaccttgt tagagaagtt gatgataaat cgcttgacac
27781 tacagctgat gagttatggt catcatcaaa atctagtact gtgctatcct cctcaatctg
27841 tgaatagcgt cccccagaga ttctgggctc ttggtctacc gacaatcttc ccgaagtgcg
27901 acggttggtg tcggaagtcg aggatctcgg agtcgtagta gcactatcgc tgatagagcc
27961 ctgtatggca gtggtactgt gtcgccttgc gtttggcggc ggctgtttgt tctgtttttt
28021 gccaaggagt tgggcgtctg tattgctgct tctgatgttg ccgttattat tgccgccttt
28081 cgttgtgttg ttcaagacgg caggtgagtg aacattagcg ccaccaagta aagatgatag
28141 cgcgtgccta atggtggagg atcttcttcg ttgttgcatg gaccctaatt tcttggtggg
28201 agagggttga aacggctgtc ctttagactg gtttaaatct gtttctgata aagagtggga
28261 tgaatttttc gccaccggtc ttgatgttat aaacggcatg cccaataggg gtagggaaaa
28321 atcttgcttg ttcttctcta tttaaaagag tcacctttcc gatggacctt caaaaatata
28381 aacgtggctt atctcagagc taagacagac cttccgagca ataataatga gtcgttctat
28441 tttttttttc tcgtcccttt ttttgtcccc tcttaacaaa attagaaata taggcgggaa
28501 agtggagaac ccttggaaga gtcagatcag agattggaaa aattaagacc aatggatatc
28561 tacagatcct gtgaatcgag tgtgagtgat ataccgcaag atcggtagaa aactgtatat
28621 aaagcaaaga actgatgtgg tgtaaacgat gtagcgatgt aacaagagat actcggtaat
28681 gtaatcaaga tgctcttttt ttttttttgc ggcaatatgg tgtacgtaaa attaaggttc
28741 cgtggagtct gtgcttgcga aaatgatatt gacgcatgga ctgtcgaaat aataaattta
28801 caattaaaca cttggtgatt tgaatgtaat ttgaacgttt aaaaaattcc aagggaatat
28861 tactgtttcg ggaatataac gtttgatatc gctagcgcac ccagatgaga aatccgcatg
28921 gatgggttgt tagtatttct attgtgaaac cgctttgttc tggagggcga gaaaaagtta
28981 cggtcactct atctttttta taatttggtc taacaaactt gatatcagaa ccacgtagaa
29041 gaaaaagaga ctaatagtaa aaatatcaag aaagttgacc aatttttgtt atatatgtcc
29101 gtaaaagtta tgacttggca ctggtcttgg tttactcatc aatcagctag gatcagcgct
29161 gagtgactgc ttgcggctgg gcggctaaga aatgggaata tgtacagtac aaattccgaa
29221 ctttgcgagc ctgcctcgat ggttttttaa ggtgttcttt tcttgcatac caaagcgtac
29281 acttgatgcg ccgcttgacg ttatcttgtt ctggatgagg ccttattttt ggtcttcatt
29341 gttaaaacac cctattgtca tttagcagcc gatgcgatga acgaaactgc gaggtaaaag
29401 cgctcaaatc aaaagtgtag tatgaatgat atataaacaa cttcaataaa gtcacgcgta
29461 gttaaaatat tgttagggta atatcctgtg tccttcgaat atctgttgga ataagaagca
29521 acatcatcta ctgactagta ttcgtgatac tagtattcaa tcacgtaagg tggaagagaa
29581 tgacatgaag attgagaaac agtgatcaaa ctcaataaag agctgaatac aagcacatat
29641 aattgttgga ataaaaatca actatcatct actaactagt atttacgtta ctagtatatt
29701 atcatatacg gtgttagaag atgacacaaa tgatgagaaa tagtcatcta aattagtgga
29761 agctgaaacg caaggattga taatgtaata ggatcaatga atattaacat ataaaatgat
29821 gataataata tttatagaat tgtgtagaat tgcagattcc ctttcatgga ttcctaaatc
29881 cttgaggaga acttctagta tatctacata cctaatatta tagccttaat cacaatggaa
29941 tcccaacaat tacatcaaaa tccacattct ctacatggta gcgcctatgc ttcggttact
30001 tctaaggaag tctcatcaaa tcaagatccg ttagccgttt cagcttccaa tttaccggaa
30061 tttgatagag attccactaa ggttaattct caacaagaga caacacctgg gacatcagct
30121 gttccagaga accatcatca tgtctctcct caacctgctt cagtaccacc tccacagaat
30181 ggacagtacc aacagcacgg catgatgact ccaaacaaag ctatggcttc taactgggca
30241 cattaccaac aaccatctat gatgacgtgt tcacattatc aaacgtcacc tgcgtattat
30301 caaccggacc cacactatcc gctgccacag tatatcccac cgctgagtac ttcctcacct
30361 gatccaatcg attcacagga tcaacactct gaagtacctc aagctaagac aaaggtgaga
30421 aataatgtct taccaccaca cactttaaca tcagaagaaa acttttatac atgggttaaa
30481 ttttacatca gatttttgaa gaactctaat ctcggtgaca tcattccaaa tgatcagggt
30541 gaaatcaaaa gacaaatgac ttatgaagaa catgcgtata tatacaatac cttccaagca
30601 tttgccccat ttcatttatt gccaacatgg gtaaaacaaa ttttagaaat taattatgct
30661 gacatcctta cagtcctttg taaaagtgtg tccaaaatgc aaactaacaa tcaagaatta
30721 aaggattgga tagctcttgc caaccttgag tacgacggaa gtacatctgc tgatacattt
30781 gaaattacgg tcagcacgat cattcaaagg ctaaaagaaa acaatatcaa tgttagcgac
30841 agattggcct gtcaactaat acttaaaggt ctatccggtg acttcaaata cctacgtaat
30901 caatatcgta ccaaaacgaa catgaaactt tcccaattat tcgctgaaat tcaattaata
30961 tatgacgaaa ataaaatcat gaatctaaat aaaccgtccc aatacaaaca acacagcgaa
31021 tacaaaaatg tttctcgcac atctccaaac acgactaaca caaaggttac aactcgtaat
31081 tatcatagaa caaatagttc aaaaccaaga gcagcaaaag ctcacaatat tgctacatct
31141 agtaaattct caagggtgaa caatgatcac attaatgaat caaccgtttc atcacaatac
31201 ttaagcgatg acaacgaact tagtcttagg ccagcaacag aaagaatcta agccaacaca
31261 cacaatagac tcgaatgacg aactacctga tcaccttctt attgattcag gagcttcgca
31321 aacgcttgtc agatcagccc attatttaca ccatgcaaca cccaattctg aaataaacat
31381 agtcgatgct caaaaacaag acattcctat aaatgccatt ggtaatcttc acttcaactt
31441 tcagaacggc accaaaacat caataaaagc actgcacaca ccaaacatag cctatgatct
31501 attaagtttg agtgagctgg ctaatcaaaa tattactgcc tgctttacca gaaacacttt
31561 agaaagatcg gatggtacag tactagctcc catagtcaaa catggagact tttactggtt
31621 atctaaaaaa tacctaattc cttcgcacat ttcaaagcta acaataaaca acgtcaacaa
31681 aagcaaaagc gtaaataaat atccatatcc gttaatacat cgaatgcttg gacatgctaa
31741 cttccgaagt attcagaagt ctcttaagaa gaatgcagtt acatatttga aagaatcgga
31801 tattgaatgg tctaacgcta gcacatatca atgtcctgac tgtctaatcg gcaaaagcac
31861 gaaacatagg catgtcaaag gatcacgact aaagtaccaa gaatcatatg agccttttca
31921 gtacttgcat accgatatat ttggtcctgt acatcactta ccgaaaagtg caccttctta
31981 ctttatatcg tttacagatg agaaaaccag attccaatgg gtctacccat tacacgaccg
32041 tcgtgaagaa tctatactca atgtttttac atcgatatta gcatttatta agaaccaatt
32101 caatgctcgc gttctagtta tccagatgga tcgtggctcc gagtacacta acaaaactct
32161 tcataagttc tttacgaaca gaggtattac tgcatgctat acaaccacgg cagattctag
32221 agcacacggt gtcgctgaac gattaaatcg tactttatta aacgattgtc gcacactgct
32281 tcattgcagt ggtctaccaa atcatctatg gttctcagca gtcgaatttt ctactataat
32341 cagaaattca ttagtctcac caaaaaacga taaatctgca agacaacatg caggtttagc
32401 tggactggac attactacta tactaccttt cggtcaaccg gttatagtta acaaccataa
32461 tcccgactcg aaaatacatc ctcgtggcat tccaggttac gccttacatc cgtcacgaaa
32521 ctcttatggc tatattatct atcttccatc attaaaaaag acagtagata ctaccaatta
32581 cgttatatta caagacaacc aatccaaatt ggaccaattc aattatgata cactcacctt
32641 tgatgatgat ctcaatcgtt taacagccca taaccaatct tttattgaac aaaatgaaac
32701 agagcagtca tatgatcaaa atacagaatc tgatcatgac tatcaatcgg agattgaaat
32761 aaactctgat cctctagtga acgacttctc gtcccaatca atgaaccctt tacaattaga
32821 ccacgaacca gtccaaaaag tacgtgcact aaaagaagtt gatgccgaca tatctgaata
32881 caatattctt ccatctcctg tacgatctcg tacaccccat atcattaata aagagagtac
32941 cgaaatgggt ggtaccattg aatcagatac tacttcacct agacactcgt ctaccttcac
33001 tgcacgaaac caaaagcgac ctggtagtcc caatgatatg attgatttga cctcacagga
33061 tagagttaat tatgaacttg aaaacatcaa aactacccgt ttgggtggta cggaggaacc
33121 atatattcaa cgaaatagtg atacaaatat caaatacagg actacaaata gtacgccctc
33181 aatagatgac cgttcgcccg acagtgactc tactactccc atcatctcca tagaaacaaa
33241 ggctgcatgc gataatacac cctccattga tacggatccg ccagaatatc gatcttctga
33301 ccatgcgact cctaatataa tgcctgacaa atcctcaaaa aatgttacgg ctgattctat
33361 tcttgacgac ctcccacttc ctgacttaac taataaatct cctacggaca cttctgatgt
33421 ttcaaaagat attccacaca tacactctcg tcagactaat tccagtttgg gtggtatgga
33481 tgattctaat gttctgacta ctaccaaaag taagaaaaga tcattagaag ataatgaaac
33541 tgaaattgag gtatcccgag acacatggaa taataagaat atgagaagtc tggaaccacc
33601 aagatcgaag aaacgtataa atctaattgc agcaataaaa ggagtaaaat caatcaaacc
33661 agttcgaacg accttaagat atgatgaagc aattacatat aatgaagaca acaaagaaaa
33721 agacagatat attgaagctt atcataaaga aattaaccaa ctattgagaa tgaacacttg
33781 ggatacaaac aaatattatg atagaaatga catagatcct aagaaagtaa taaactcaat
33841 gtttatattt aacaaaaaac gtgatggtac acacaaagcc agatttgttg caagaggcga
33901 cattcaacac cccgatacat atgattctga tatgcaatcc aataccgtac atcactatgc
33961 actgatgacg tcattgtcaa tcgcattaga caatgactat tatatcacac agctggacat
34021 atcctctgct tacttatatg ctgatatcaa agaagaatta tacataagac ctccaccaca
34081 tttaggtttg aatgataagt tactacgttt gagaaaatca ctctatggtt tgaaacaaag
34141 tggtgcaaac tggtatgaaa ccattaaatc atatttaata aattgttgcg acatgcaaga
34201 agttcgcgga tggtcatgcg tatttaagaa tagtcaagta acaatttgct tattcgttga
34261 tgatatgata ttgttcagca aagacttaaa tgcaaatgag aaaatcataa caacactcaa
34321 gaaacaatac gatacaaaga taataaatct gggtgaaagt gataacgaaa ttcagtacga
34381 catacttgga ttagagatca aatatcaaag aagcaagtac atgaaattag gtatggaaaa
34441 atccttgaca gaaaaattac ccaaactaaa cgtacctttg aacccaaaag gaaagaaact
34501 tagcgctcca ggtcaaccag gtcattatat agaccaggat gaactagaaa tagatgaaga
34561 tgaatacaaa gagaaagtac atgaaatgca aaagttgatt ggtctagctt cttatgttgg
34621 atataaattt agatttgact tactatacta catcaacaca cttgctcaac atatactatt
34681 cccctctagg caagttttag acatgacata tgagttaata caattcatgt gggacactag
34741 agataaacaa ttaatatggc acaaaaacaa acctaccaag ccagataata aactagtcgc
34801 aataagcgat gcttcatatg gtaaccaacc atattacaag tcacaaattg gtaacatttt
34861 cctactcaac ggaaaagtga ttggaggaaa gtcgacaaag gcttcgttaa catgcacttc
34921 aactacagaa gcagaaatac acgcagtcag tgaagctata ccgctattga ataacctcag
34981 tcaccttgtg caagaactta acaagaaacc aattattaaa ggcttactta ctgatagtag
35041 atcaacgatc agtataatta agtctacaaa tgaagagaaa tttagaaaca gattttttgg
35101 cacgaaggca atgagactta gagatgaagt atcaggtaat aatttatacg tatactacat
35161 cgagaccaag aagaacattg ctgatgtgat gacaaaacct cttccgataa aaacatttaa
35221 actattaaca aacaaatgga ttcattagat ctattacatt atgggtggta tgttggaata
35281 aaaatcaact atcatctact aactagtatt tacgttacta gtatattatc atatacggtg
35341 ttagaagatg acacaaatga tgagaaatag tcatctaaat tagtggaagc tgaaacgcaa
35401 ggattgataa tgtaatagga tcaatgaata ttaacatata aaatgatgat aataatattt
35461 atagaattgt gtagaattgc agatcccctt tcatggattc ctaaatcctt gaggagaact
35521 tctagtatat ctacatacct aatattatag ccttaatcac aatggaatcc caacaattac
35581 atcaaaatcc acattctcta caataataga ataatgaacg ataacacaca ctatgaaaga
35641 agaataataa taataacact gtatagaaat agcggctccc tcttgtttat tctcacatcc
35701 tcgagcaaaa cttctagcaa atcctgtgta tttaatatta tggcctctat cagcaatgga
35761 ctcccaataa ttatccaatt actcaccaat ttttcaatat tagtgtagat aggaaaggat
35821 cctcgatgaa atcgttatgg ttagtgtctc tgttgataat tagaggttaa aaattagtat
35881 taatgaagaa gtgagtactg atcttcttat actaaataag agaggtatat aaaacacacg
35941 ccgattggtc atattaatta tgaccaatat aatagtgatt ccggtagtta ctatacattg
36001 atgtgacgac tcatattcct catatatgta cctaccataa catgttcaac taataggtct
36061 ttaacacagc ttcagtattg tctgagcttc tcgtttaaca ttccttctgc aataggcgca
36121 atcacactta aacgtatacg agttgtacat taatatacga tgtaagcatt agattgttac
36181 catagcaact catgtcacta ttaattactc tcgttccaac agtctcgatc cactgtgtgt
36241 attcttggaa aatgaacaaa tcagtgtaga gaagtcgtct tcgtttccat catgagaatg
36301 tgcttcagta ttacattttt tgccttcaac gccttgattg ttctattttt gctaataata
36361 aatctatttc atcggactaa aagtccatta gttgtaagcg gatttagctc agttgggaga
36421 gcgccagact gaagaaaaac ttcggtcaag tcatctggag gtcctgtgtt cgatccacag
36481 aattcgcatt cctttttgct agcattcttt tttttttcat ttctaggcct gtttctccgc
36541 gctgattggt cgcccgggtg atgcagttgc ggccggccct ggccaatcag atccctttaa
36601 aaatgggccc ggtgcgcttc taccccttca cgccttttac gcctttttcg aatcttgtat
36661 ttattgtaat tattatacat tggtcatatc aaattcacat cagacttcaa tttttcaatt
36721 cactttctga ataagagccc ttcccttcat acaagtagag atattatact gtcatagctc
36781 tttcaattgg tcttattaga ttgtctccat ctttcccatt gacgttgtta ctccctctct
36841 tttttcgttt ttaactgatt tctcatatat tcccaaacag gcatatatac tcgacgtcaa
36901 gaaagaaaag aaaagaaaac cctcataaaa aatataatcg agaagttttt ttcctcatcg
36961 cgaaccatta gtataacaga ttgatcgttc agctctcata actatcgcaa gaacagtaac
37021 aaaataaata aaaaaaacac gcacatataa taatgttggc tcgtactgct gctattcgtt
37081 ctctatcgag aactctaatt aactctacca aggccgcaag acctgccgct gctgctttgg
37141 cttccaccag aagattggct tccaccaagg cacaacccac agaagtttcc tccatcttag
37201 aggaaagaat taagggtgtg tccgacgagg ccaatttgaa cgaaactggt agagttcttg
37261 cagtcggtga tggtattgct cgtgtttttg gtttgaacaa cattcaggct gaagaattgg
37321 tcgagttctc ctctggtgtt aaaggtatgg ctttgaactt ggagcctggt caagtcggta
37381 tcgttctttt cggttccgat agactggtta aagaaggtga attggtcaag agaaccggta
37441 atattgttga tgtcccagtc ggtccaggcc ttttgggtag agttgtcgac gctttaggta
37501 accctattga tggtaaaggt cctattgacg ctgccggtcg ttcaagagct caagtcaaag
37561 caccaggtat tttgccaaga agatctgtcc atgaaccagt tcaaaccggt ttgaaagccg
37621 ttgacgcctt ggtccctatc ggtagaggtc aaagagagtt gattattggt gatcgtcaaa
37681 caggtaagac tgctgtcgcc ttagacacca tcttgaatca aaagagatgg aataacggta
37741 gtgacgaatc caagaaactt tactgtgttt acgttgccgt tggacaaaaa agatctaccg
37801 ttgctcaatt ggtccaaact ttggaacaac atgacgccat gaagtactct attattgttg
37861 cagctactgc atctgaagcc gctcctctac aatacttggc tccatttact gccgcatcca
37921 ttggtgaatg gttcagagat aatggaaagc acgctttgat cgtctatgac gatttgtcca
37981 agcaagccgt ggcataccgt caattatctt tgttgttgag acgtcctcct ggtcgtgaag
38041 cctaccctgg tgatgtcttt tacttgcatt caagattgct agaaagagcc gctaagcttt
38101 ctgaaaagga aggttctggt tctttaactg ctttgcctgt tattgaaacc caaggtggtg
38161 atgtctccgc ttatattcca accaatgtta tttccattac cgatggtcaa attttcttgg
38221 aagctgaatt attctacaag ggtatcagac ctgccattaa cgttggtttg tccgtttctc
38281 gtgtcggttc cgctgctcaa gttaaggctt tgaagcaagt cgctggttcc ttgaaattgt
38341 ttttggctca atacagagaa gtcgctgctt ttgctcaatt cggttccgat ttagatgcct
38401 ccaccaagca aactttggtt agaggtgaaa gattgactca attgttgaag caaaaccaat
38461 attctccttt ggctacagaa gaacaggttc cattgattta tgccggtgtt aatggtcatt
38521 tggatggtat tgaactatca agaattggtg aatttgagtc ctcctttttg tcctatctaa
38581 aatccaatca caatgagctt ttgaccgaaa ttagagaaaa gggtgaattg tctaaagaat
38641 tgttggcatc tctaaagagt gctactgaat catttgttgc cactttttaa tgtgaactaa
38701 aaaaataaaa atgaatataa ggtacgtctc aaaaagaaat gtaaatatag aaattttaaa
38761 aaaaaaaacg aaaaaaaaca taactaaatt taaagtgcag ccaaacaata accctgaaaa
38821 atctaaatat cttagaattt ttttattttg attattatat attattatta ttcttatggt
38881 aaataatgcc cctacttttc ttctaaggaa atgagttact acaaaaataa ggaaatatcg
38941 cctgcaagcg gtttttattt tggagttgtt tttttttttc ccacaatagc ctctagttta
39001 ttccattctt agcactgact cttttttccg ccactatttc ttataaaagg cccgaatttc
39061 tggcacggac gttgttttta ataataaaat attgaatgac agttaaaaaa tcacgtagtc
39121 agttaatctg tttaacttga aaatatgtct gaatcagtgg ccattatagg tgcaggatta
39181 gtaggctgcc ttgcagcttt ggcattctcc aaagaaggct acaatgtcac actatatgat
39241 tttagacaag atcctcgatt ggacaccacc aaaaataaaa atttgaaatc cattaatttg
39301 gctatttctg ctcgtggcat tgatgctctg aaatcaatag atccggatgc ttgtgaacat
39361 attctgcaag atatgattcc catgaaaggc aggatgattc atgacttgaa aggcagacag
39421 gaatcacaat tgtatggctt gcatggagaa gctattaatt ctatcaatag atctgtatta
39481 aataatagcc ttttggacga attagaaaaa tctacaacag aactgaagtt cggtcacaaa
39541 ttagtcaaaa tcgaatggac agatgataaa caaatctgtc attttgccat tggggaagat
39601 ttgaaaaccc cacatactga aaagtatgat tttgtcatag gttgtgacgg agcatactct
39661 gcgacgagat cgcaaatgca acgtaaagtt gagatggatt tttcacaaga atatatgaat
39721 ttacgttaca ttgaacttta catcccgcct actgaggaat tcaagccaaa ctatggcgga
39781 aattttgcaa tagctcctga ccatttgcac atttggcctc gtcataaatt catgttaatt
39841 gcgctcgcca acagtgacgg ctcgttcact tcaacctttt tcggttctaa agatcaaata
39901 tcagatctga taacttccaa gtcacgtgtg agggaattct taatcgagaa ctttcccgat
39961 attattaata ttatggattt ggacgatgct gtcaaaaggt ttatcactta tccaaaggaa
40021 agtcttgtct gtgtaaactg taagccatac gatgtaccag gcggaaaggc catcctactc
40081 ggcgacgctg cccatgcaat ggttccattt tacggccaag gtatgaattg cggatttgaa
40141 gatgtgagaa ttcttatggc gctattgaaa aagcattcag gagatcgttc aagagccttt
40201 actgagtaca ctcaaacaag acataaggac ctagtttcta ttactgagct ggcaaaaagg
40261 aactataaag aaatgtcaca tgacgttaca tccaagcggt ttttattaag gaaaaagcta
40321 gatgctctct ttagtattat aatgaaggat aagtggatac ctttgtatac aatgatatct
40381 ttcagatccg atatctcgta ttctagagct ttagaaaggg ctggaaagca aacacgtatc
40441 ttgaaattct tagaatctct gacactcggt atgttatcta ttggcggtta caagcttttc
40501 aaatttttga caagagaacg ttcctgaagc cagtttattc ttgccatccg tgtacgctag
40561 gagaggatta ttaaaataag tgatatatac atatatatat atatatatat atatataata
40621 cactaattat tttatgtgat gttgatcacg cgaaacggta aacggctctg ttcgcgcttt
40681 ctttgtttac attttagtga agtattgtca agataatatc catatggttg aactttttat
40741 attggctagt taaatactct atttattgca ccaaaaaatc atcttagtgg actttttgga
40801 gcaaaaaaaa ccagcaggta gttatataag atgactacac aactaaggta tgaaaataac
40861 gatgacgatg aaagagtaga atataatctc tttaccaata gatccaccat gatggcaaat
40921 tttgaagaat ggatcaaaat ggctacagat aataaaatca attcccgaaa tagttggaat
40981 ttcgcattga tcgactattt ttatgacttg gacgttttga aagatggcga gaataacatc
41041 aattttcaga aagcatctgc aaccttggat gggtgtatta agatttactc ttcgagagtt
41101 gattcagtga caacggaaac aggtaagtta ttgagcgggt tggcacaaag aaagacgaat
41161 ggggcatcta acggagatga cagtaacggg ggaaatggtg aagggcttgg aggtgacagt
41221 gacgaagcaa atatagagat tgatccctta actggtatgc ctatatctaa tgatcctgat
41281 gtgaataaca ctaggcggag agtgtacaac agagttttag aaacaacatt ggtggagttc
41341 gaaacgatca agatgaaaga gctagaccag gaattaataa ttgatccatt attcaaaaag
41401 gccttggttg atttcgatga aggtggcgcc aagagtttat tgttgaacac attaaacata
41461 gacaacactg caagagtcat tttcgatgca tcaattaagg atacacaaaa cgtagggcaa
41521 ggtaaacttc aaaggaaaga agaagaatta attgaaagag atagtttagt agatgacgaa
41581 aatgaaccta gccagtcatt gataagtact cgtaatgact caaccgtaaa tgattccgtt
41641 attagtgcac cttccatgga agatgagatt ttatctcttg gtatggattt tataaaattt
41701 gatcaaattg cggtgtgtga aatttcagga tcgattgagc aactaaggaa cgttgtcgaa
41761 gatattaatc aagcgaaaga ctttatcgaa aatgttaaca acagatttga taacttctta
41821 actgaagaag aattgcaagc agctgtccca gataatgcag aagatgatag cgatggcttt
41881 gatatgggca tgcaacagga gctgtgctat ccagatgaaa atcatgacaa tacatcacat
41941 gatgaacaag atgatgataa tgtcaacagt accacaggaa gtatattcga aaaagatttg
42001 atggcatact ttgacgaaaa tctaaataga aactggagag ggagagaaca ttggaaagta
42061 cgaaatttta agaaagcaaa cttagtgaat aaagaatccg acctgttgga agaaacgcga
42121 actactatag gagatactac tgacaaaaac acaacggacg acaaatcgat ggatacgaag
42181 aagaagcata aacaaaaaaa ggttctggaa attgatttct tcaaaacgga tgatagtttt
42241 gaagacaaag tctttgcctc aaaaggaagg acaaagattg acatgccgat taagaacaga
42301 aagaacgaca cacattattt actgccggat gacttccatt tttccactga tagaataaca
42361 agattgttca ttaaaccggg gcagaaaatg agtctgttca gtcataggaa gcataccaga
42421 ggcgacgtta gttcggggct ttttgaaaaa agcacagttt ctgccaacca ttcaaataac
42481 gacattccta ctattgcaga tgagcacttt tgggcggata attacgaaag gaaagaacaa
42541 gaggaaaaag aaaaggagca gtctaaagag gttggtgatg tggtgggtgg agcgctcgat
42601 aatccgtttg aagatgacat ggacggtgtt gacttcaacc aagctttcga aggaacagat
42661 gataacgagg aggccagtgt gaaacttgat ttacaggatg acgaagatca taagttcccc
42721 attcgagaaa ataaagttac ttattcaaga gtttcgaaaa aagttgacgt aagaagatta
42781 aagaaaaacg tatggagatc gatcaacaat ttgatacaag aacatgacag taggaaaaat
42841 agagaacaaa gctctaatga cagtgaaacc cacacagaag atgaatcaac aaaggagctc
42901 aagttttctg atatcattca gggtataagt aaaatgtatt cggatgatac actaaaggac
42961 atttcaacaa gcttttgttt tatatgcctt ctacacttag ccaatgagca tgggttgcag
43021 ataactcata ccgaaaacta taatgacttg atagtgaatt atgaggatct agcgacaaca
43081 caggcagcgt catagttgat gatctttttt tttttttttt tttttttttt tgtgctgcaa
43141 agtttcttaa agccttcggg cttacgaaat cctttatcgc cgaaagggga ccgcttcgaa
43201 aagtggatat aaaacaaggt atttattttt atagacaatg accaaatgac aggatagatc
43261 gagggtgagt tccaatatgt ccagaactat tccatttcta tttaaattag tcaacagggc
43321 agtaattttg cctacggcag gttttacatt aggagttggt gcgtttgtaa aggcgtggcc
43381 cgatgatgcc ggtgttctat cattgaatga tccgcaaacg ccagcggagt tgattagtgc
43441 gaccaagagc cgccaaccta tggagctgca gagggttgac atcctcgctc aaatcgagaa
43501 aagcgaggtt tacaacaagt tggcccagga tgagaagatg caccatgtct tattcagtga
43561 gaaaatacca agcgggcata gggaatatca tgtaggacaa ggcctcttgt tcggcaaggg
43621 gaagcttgaa attgatcctt tggtgttcca tgatgtgaat cacggtgaat taaccgtgat
43681 ttatcactta ggtgctgagt tagggaatcg agacggtaac gtccataagg gcttgttgtc
43741 attgttgctg gatgaagcat tgtgctattg tggcttccct ttgttgccta gtaaaagagg
43801 tgtaactgca aggctgtcgc tagagttttt tgaggacatt cctgtagata ctacgattat
43861 actaaaagca aacgtcaaag agattaaagg cagaaagtgt atcattgagg gacacttgga
43921 acagtttccg ttggaagttt cttctcgaaa tggaactaga agttggaact taccacatat
43981 ttggggtttc aaccataagc aggagatggc aaaaaaattt gccaaggcca attgtattct
44041 cgttgagcct acttggttca aatattttaa atggcttgat atgttttgaa aaagcatgcc
44101 tgtctcaaaa tagcctattc cgtgttaatt aatattctat attcaaaaaa gttaaacata
44161 tatactgcat gtacttaccg ccgaagcaca aacgtgccac ttccatgaac acttgctctt
44221 tatttatagt ggggctgata tgcgatggcg taaagctact ccagcctcct tcttttcata
44281 tcctcatgac tgtcactatg tgttggtgta gccatcgaac ttccactaga tttgttcttc
44341 cttttcttac tattgttacc tgaatttgag ccggattggc tttttcctgt accgtctaga
44401 tcaaacgcca agtcgtctat atcaaacggc gcttgggctc ccccttggtt ctggtttgcg
44461 aactcgcttg gatatgacct ttcaaactgc gatagtaccg aagagcaaag gtcccaatcg
44521 aaatttggag gctgaaacaa tgctatgtct ctattgcgca gctgttcgcg ccattgttgc
44581 tctgacatgt tttgaccctg ctgaggtggt tgtatcatca tgtctgggtt attttggaaa
44641 agaatatgtg ctatttgacc acctttacca ttttctctgg tcggtatggt ggagaattta
44701 cctgaaagat ctgctatctg gttcttgtaa gattttctta gcttcacggc tttagtgccg
44761 tccaaatttg ttcttgccac ttgcctggag atgtcatcca agccatacac cgatatcaag
44821 tcctgtagag gatttggttg ttggtacgta tatgtagttt ccggatccac gtaatagtag
44881 tatgagggga ctgtagtttc gtccactcta gaagccatta ttatcgtatt cctttttcgt
44941 tcacttacta ttgctattcg cactcactac agatctatat tttatgttcc accctgttgt
45001 cagatcagga aaggaatgaa gaggctctat ttaaaccaaa tacacctctt cgtttctcaa
45061 tattgttggg ctttcctttt ttttttcctt ccacgtctat ctattgtctc tatcaaaatt
45121 aggaaaaaga aatgaagaac gatgagccaa acgaggctga gacaatcatg catccgtaca
45181 ttctatgtat gtttgggtgt atctttccag attcggttct tttttttttt cagtccaatt
45241 gaaaaaaaaa aggaacagga acaacgggtc gaaatttgcc gtcacattca gagcgaagag
45301 cgacagggga attggtgggc taaccacctg ttgagcccag ctagcagctg tcggtaaacc
45361 gtcgttgggc ggggcgcgac aatgcagcca gcggaggcat tgtatggttt ccgtctggag
45421 agtgggctta gccggcctgg cactccttct ctaagcagag tgagaaggga atctttttac
45481 tggagaagag tgtttgaatc cagcagaagg taatacgcac ctttctcatc tatttgcaga
45541 atcgttttat taaaatactt ttaaagaatt tagattttga taattagttc attctctttt
45601 acaaagataa tcaccaaaca gggacaatac actgaacgat aaaagtatgt gacatataga
45661 atgctagaat gaatagccta gactgcattg ttatgagagc aacgtttgat atttgtggcg
45721 attggaacaa acatagtaca tgccaaaatg agatgaaatg tccaatttga actgattaac
45781 atacacgcgc aagctcgtat ttgtttactg gtacacctag agttagccga tcaaagagac
45841 agtggcagat atatgggaaa attttctccg gaagattgca tgcgagagtc tcataaccag
45901 tcatttccca agatacaatt ctcggagctg ttatactaac aaacttttaa ttttcatttt
45961 tttttttttt tgattagatg gcctccttac ctcacccaaa gattgtcaag aagcacacca
46021 agaagttcaa gcgtcatcac tctgaccgtt accacagagt tgctgaaaac tggagaaagc
46081 aaaagggtat tgactctgtt gttagaagaa gattcagagg taacatctct caaccaaaga
46141 tcggttacgg ttctaacaag aagaccaagt ttttgtcacc atctggtcac aagactttct
46201 tagtcgctaa cgttaaggat ttggaaacct tgaccatgca caccaagact tacgccgctg
46261 aaattgctca caacatctcc gctaagaaca gagttgtcat tttggctaga gctaaggctt
46321 tgggtatcaa ggtcaccaac ccaaagggtc gtttggcttt ggaagcttaa attaaataaa
46381 gatttacaaa ataataacct tcatttaatt ttaaatttca ataaaaaaat atcaaatcaa
46441 acatgacttt taaatctacc attagataat tgtataaagt gatttattgt tttttaattt
46501 tgttttcatt atctatcaaa actagggcat tcttcctcac ttttagtgat aaacttttgt
46561 aaactcagta gtatatccag ccgacgagca atgcgataac ggtgatgata agcaatgctc
46621 tggaactcag actttgcccg ttacctgctg atggcgctct tgctgattct gcatcgtggt
46681 ttccagacgg ttttcttttc ggtaacacgg agtgaaatat tttgatcttc ttgaagacta
46741 tgtcatcttt gtactgctct tccagattag gccaatcgga caacagctcg ccatcctcca
46801 cgttttggta agctgccggg ataggaagtg taacgatcaa gaatttgtct cgtttttggt
46861 ccatttcatc gtcagcggtt gacttgggta atccaaggaa aacaatttgg acatttacac
46921 tttcatgagc acctatgatg gccacattgg gcctcacaca atactttgtg ggagcactag
46981 tcctcacttt aaatataact ctcttttcac catcgttctc gagctttata tactctgttg
47041 attgtttatt aaggggagct gaagtattac atattagtaa cctgttgcat cgcaccaaaa
47101 aaggtagcaa agtttcccgc acactagcaa ttctcgtcaa acataccctt gaacaccagc
47161 ttttctggca ctattctcat tgtttactcg tctgaactag tgcttatatt atctgtcgtc
47221 ataccactgt ttgagacccc cataggtctt atataaggta atgcatcatt ctaaacgggc
47281 ggcaagccat attaaactat ctatataact acaacagtat tcatatacct agtgaggagg
47341 ccatttgaaa gcgcatttta cctcagtagt catcaccttt cgaaacgact tcctttttgt
47401 gagcatgcaa caagatggtg tgttcgaatt gtgcagtgta ggatccgggg atatcgttca
47461 atggtggata atcctgtact aaaccgtgtc taaccaagtt attcaacgca aataagtatt
47521 tctcttggcc aagtctgtct aggtatcggc gacagaacgg taaagtccca aagttgcggt
47581 ctatcgtttt taacaagttc ttggcgctgt ctaacgtggg cattacctga tggtcttcag
47641 cagatctggc ataatgagaa acttccccac cggcagtaac ataacctcta ccagtagaac
47701 caaaagtttc aatggcaaag tgctcacctt cctccatttt tgtagtgtcc ccatttttga
47761 cgatgggaac ggatttaccg ccgtggatac gatatggtgc gatactgtgg ccacatagat
47821 tacgacaagg tttaacctgg taagtctcac cattgatttc cacttcgtag gattccataa
47881 cttcttggat ggcttcaccg atgtcggtta atctcacatc gatacccgct tctttaatac
47941 ccgtgtaagt agcgtccttt acagcggcta gcaggttatc gtattgtgga tcaaaggaaa
48001 cagtaaaggc agaatcaatg atgttaccgt ttacctgcac accataatct accttcatca
48061 cgtcttcgta tttcagaacg gttttgtcgc ctgcattggg tgtgaaatgt gcagcacaat
48121 ggttgagaga gagacccgtt ggaaacccaa taccttgaga tttgggatcc tccatcgcta
48181 ataaattttc ggcacctgta tactttcttg tagtattttc gatcatgtca gcgatatcca
48241 ttaacttcat cccaggaacg attctgtcct tgatggccct tctcacacga cgatgtatct
48301 cagcaccctt tctgacatca ttccaatgtt cggccctttc cagatccctt ttcaaataac
48361 gtgattcttc atccgtggtt ctttgcagat tgaaatcttg atgatagtcc atccacgcac
48421 cttctgggta ctttccatct ggaaacagta attcaatctt cttcacattg cttttcttct
48481 tcttcttttt cttgttcttc ttctttttgc tttctactgg gtctgactcg tcagcttttg
48541 cctggtcttg ctgttcaacg ccttcattct ccaaattcaa ttcttttaaa tcagaagcag
48601 gggaattttc tatttcagcg tctgtcattt ttcaatacgg tagagcttct acagtacttg
48661 ttgatgtaaa agcccactta ttagcttctt gctatggctt cctttctttt ttaagttcgc
48721 ttctttccca agattgaaaa taaaaaataa gtgagaccag gtcattaaag gtcccttgaa
48781 gagtaaaaaa tctgtcaaat atcacccata agagcataac cataatgttg aagagcacgc
48841 tgaggctttc aagaatctct ctcagaagag gtttcacaac gatcgactgt ttacgccaac
48901 aaaattcgga tatcgataaa atcatactaa atccaatcaa attagctcag ggaagcaaca
48961 gcgatcgtgg ccaaacctct aaaagcaaaa ctgataatgc agatatttta tcaatggaaa
49021 ttccagtaga tatgatgcaa tctgctggga gaataaacaa gagggagctt ctatccgagg
49081 cggaaattgc tagaagtagc gtggagaatg cacaaatgag attcaattct ggaaaatcta
49141 taatcgtgaa taagaacaac cctgcagaat catttaagag attaaacagg atcatgtttg
49201 agaacaatat tcccggagat aaaagaagtc aacggtttta catgaagccg gggaaagtgg
49261 ctgaattgaa gagatctcaa aggcatagga aggaattcat gatgggcttc aagaggttga
49321 ttgaaattgt taaagatgcc aagaggaaag gatactaatc gtaccatcaa ctcttgaata
49381 ttgtgaaatt ttcgccattg atttccgtct ttgtaaatag gtaatgcgta actatttagt
49441 taaatttttg tatatttttt attctatgac ttcacttatc cattatttcc atcgtcaaaa
49501 aaaggaaata aatactgttg ctcgaacgaa cagcaagata aagtggaaac gaaaagtaag
49561 cagcttcctc aatatgccgt caaacgtacg ttcgggagtc ttaactttgc tccatacagc
49621 atgtggagca ggcgtacttg caatgccgtt tgcattcaag ccatttgggt taatgcctgg
49681 tctgataacg ctaacatttt gcggaatatg ttccttatgt gggctgctat tacagactcg
49741 aatagcgaag tacgtaccta aatctgagaa cgcctcgttt gctaaactca cccaactaat
49801 caatccgtca ataagtgtag tgttcgattt tgccattgct gttaaatgtt ttggcgttgg
49861 tgtatcttac ttaattattg ttggtgactt agtgccacag atagtgcagt caatttttta
49921 tcgtaacgat gataacatga gtggttcgca agagcatcac atgttcttag acaggcgttt
49981 gtatataact ctgatcatag tgtttgttat ctccccttta tgctttaaaa gaagtttgaa
50041 ttctctacga tatgcttcta tgattgccat tgttagtgtc gcatatttat ctggtttgat
50101 tatttaccat tttgtaaatc ggcatcagct agagagaggg caagtatatt ttatggtacc
50161 tcacggagat tctcagtctc attctcccct gactacattg ccaatttttg tgtttgctta
50221 cacttgtcac cacaatatgt tcagtgtaat taatgagcaa gtggataaga gcttcaaggt
50281 aatcaggagg attccgattt ttgccatcgt gttggcctat tttttataca tcataattgg
50341 tggtacaggt tatatgacat ttggtgagaa tattgtagga aatatcctca ctttataccc
50401 gaattccatc tccaccacca tcgggaggtt agcaatgctg ctattagtta tgttagcatt
50461 tccattgcaa tgccatcctt gcagatcatc ggtaaaaaac ataattatat tcattgaaaa
50521 tttcagaaaa ggtaagttat acgataacag agctagcttt attccattag acaactttaa
50581 tagtgaagat ccgcaggagg cgccaaccca acaaaacaac gaagagccaa atctgcgtag
50641 tgagtcttta cggcatatca atattatcac cctttgtatc ttactgttct catatctact
50701 ggctatttca attacgtctc tagcaaaagt cctagcaata gttggtgcca cgggatctac
50761 gtcgatttct ttcattttgc caggcctttt tggttataaa ttaattggct cagaatttac
50821 gggcacgaat gaaagagtac cgacaagcat aaaaatattc aaatacttaa gtttatctct
50881 attcatctgg gggatagcag taatggtagc ttcactatca gcgattgtat ttttgggcac
50941 atcatcacat tgagtttgta cattactttt cgtatttcta taaacaaaaa aaagaagtat
51001 aaagcatctg catagcaatt aataaaaagg tgaccatccc atatatataa cactcaaatt
51061 tgatggatcc gtggcttgct gaatcaaatc ttgtacgcta gactctacac ttagtccatt
51121 acccataagc ttctcttcta cacctttaag ggccctataa gactcttggt tttcgttcct
51181 gtcgttgtta cttatgaact tgctgacgtt atcgaaattt gtaatttcat gttcttcttc
51241 aaataagtgt tcgtattttt taactggtga cattacccag gaataaaggg gatcccattt
51301 taagatattc aaaacacaca tcaccttgac ataatctttt cttaatactg cgtaaactct
51361 ttcacaactc cgcctgaata ggccatccac gcctgtgact ccaaatccat caacgatatc
51421 tctagttaat ctgaaaggga ccaactctgg aatggggagt aattttccct gatcaaacgc
51481 aattcccagg tctatatgaa taggctcccc tgttgagcag tcaagcagga tattgtttaa
51541 gtgcctatca ccgaggccta atatgtatcc aacgatagag ctagctgcga caccttttgt
51601 gtacgttttc ttagcttcaa accaatccaa cggatcggga aaggaatcaa aaaaaaagtt
51661 tcttaactgc ggttttattt cattagtgat ttttaaataa gctttcagcc tctcttcatt
51721 tgattttgtt tgaactgctt tcatgccttt tcttgcctga tcgaaggtta tcttatcgtt
51781 ggtatgtagc ttactcaaaa tttgatgtaa tgatgtagaa tttgcgacaa attcaatgat
51841 tcctgccttt ggtcctaatg gaaccacttt gtatgttcta atacccagat ctagatttct
51901 taatacttta tcattttgta gaactttatt aacttgttga aacacttgtt ccataattgc
51961 atcttgtctc aaatcgtcat tacttccttt catcaaagct ttctgcgttg taccatctga
52021 gatgttgaag gtgactattt tcggcaggga caatcctgtg gtagtaatgc ctactgtttc
52081 attgacggat acaatataag ggcgggcttt tcttccatca gcagaacttt tgactgtaaa
52141 attactggtc ggtaggggaa gcttctccat gtttagctgt ttcagccaat attggccaat
52201 cttcaaatta gctaagcgta acgtcttcgt attttgcaca aacttaagat tagctaactc
52261 tacagacatc tcgcaaaact cttgcacagg aagtaaatac tttttcgcaa aggcacccct
52321 gtcatatcct tgcaattcta aaagaatctt tttgacagct tgaatttttt gggata 