LOCUS       NP_247585                422 aa            linear   BCT 21-DEC-2012
DEFINITION  glutamate-1-semialdehyde aminotransferase [Methanocaldococcus
            jannaschii DSM 2661].
ACCESSION   NP_247585
VERSION     NP_247585.2  GI:161579526
DBLINK      Project: 57713
            BioProject: PRJNA57713
DBSOURCE    REFSEQ: accession NC_000909.1
KEYWORDS    .
SOURCE      Methanocaldococcus jannaschii DSM 2661
  ORGANISM  Methanocaldococcus jannaschii DSM 2661
            Archaea; Euryarchaeota; Methanococci; Methanococcales;
            Methanocaldococcaceae; Methanocaldococcus.
REFERENCE   1  (residues 1 to 422)
  AUTHORS   Bult,C.J., White,O., Olsen,G.J., Zhou,L., Fleischmann,R.D.,
            Sutton,G.G., Blake,J.A., FitzGerald,L.M., Clayton,R.A.,
            Gocayne,J.D., Kerlavage,A.R., Dougherty,B.A., Tomb,J.-F.,
            Adams,M.D., Reich,C.I., Overbeek,R., Kirkness,E.F., Weinstock,K.G.,
            Merrick,J.M., Glodek,A., Scott,J.D., Geoghagen,N.S., Weidman,J.F.,
            Fuhrmann,J.L., Nguyen,D.T., Utterback,T., Kelley,J.M.,
            Peterson,J.D., Sadow,P.W., Hanna,M.C., Cotton,M.D., Hurst,M.A.,
            Roberts,K.M., Kaine,B.B., Borodovsky,M., Klenk,H.P., Fraser,C.M.,
            Smith,H.O., Woese,C.R. and Venter,J.C.
  TITLE     Complete genome sequence of the methanogenic archaeon,
            Methanococcus jannaschii
  JOURNAL   Science 273 (5278), 1058-1073 (1996)
   PUBMED   8688087
REFERENCE   2  (residues 1 to 422)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 422)
  AUTHORS   Bult,C.J., White,O., Olsen,G.J., Zhou,L., Fleischmann,R.D.,
            Sutton,G.G., Blake,J.A., FitzGerald,L.M., Clayton,R.A.,
            Gocayne,J.D., Kerlavage,A.R., Dougherty,B.A., Tomb,J.-F.,
            Adams,M.D., Reich,C.I., Overbeek,R., Kirkness,E.F., Weinstock,K.G.,
            Merrick,J.M., Glodek,A., Scott,J.D., Geoghagen,N.S., Weidman,J.F.,
            Fuhrmann,J.L., Nguyen,D.T., Utterback,T., Kelley,J.M.,
            Peterson,J.D., Sadow,P.W., Hanna,M.C., Cotton,M.D., Hurst,M.A.,
            Roberts,K.M., Kaine,B.B., Borodovsky,M., Klenk,H.P., Fraser,C.M.,
            Smith,H.O., Woese,C.R. and Venter,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-AUG-1996) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AAB98593.
            On Dec 3, 2007 this sequence version replaced gi:15668783.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Methanocaldococcus jannaschii DSM 2661"
                     /strain="DSM 2661"
                     /db_xref="taxon:243232"
     Protein         1..422
                     /product="glutamate-1-semialdehyde aminotransferase"
                     /EC_number="5.4.3.8"
                     /calculated_mol_wt=46876
     Region          1..421
                     /region_name="PRK00062"
                     /note="glutamate-1-semialdehyde aminotransferase;
                     Provisional"
                     /db_xref="CDD:178834"
     Region          7..418
                     /region_name="OAT_like"
                     /note="Acetyl ornithine aminotransferase family. This
                     family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). The major
                     groups in this CD correspond to ornithine
                     aminotransferase, acetylornithine aminotransferase;
                     cd00610"
                     /db_xref="CDD:99735"
     Site            order(111..113,139..140,142,201,234,236..237,262)
                     /site_type="inhibition"
                     /note="inhibitor-cofactor binding pocket"
                     /db_xref="CDD:99735"
     Site            order(112..113,139..140,201,234,237,262)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99735"
     Site            262
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
     CDS             1..422
                     /locus_tag="MJ_0603"
                     /old_locus_tag="MJ0603"
                     /coded_by="complement(NC_000909.1:533791..535059)"
                     /note="Converts (S)-4-amino-5-oxopentanoate to
                     5-aminolevulinate during the porphyrin biosynthesis
                     pathway"
                     /transl_table=11
                     /db_xref="GeneID:1451468"
ORIGIN      
        1 mdkskelfee akkylvggvn spvryfkpyp ffvekakdcy lfdvdgncyi dyclaygpmv
       61 lghandavik avkeqlelgs aygcptekei ilakevvkrv pcaemvrfvn sgteatmsai
      121 rlargvtgrk kiikfdgayh gahdyvlvks gsgalthghp nspgipeett kntilipfnd
      181 edavkkaine nkdeiaciiv epimgnvgci lpkegylefl reiteendil lifdevitgf
      241 rlakggaqey fgvvpdiatl gkilgggfpi gaivgrrelm eqfsplgaiy qagtfngnpi
      301 sitagiatlk qlddrfyket artakiladt lreladkhni kakvyniasm fqiyfndkev
      361 vnyeiakqsd tekfmkyfwr llekgvfvpp sqfeccftsi khddevvdkt ikamedvfeg
      421 le
//