LOCUS NP_415220 732 aa linear BCT 04-MAR-2013
DEFINITION ornithine decarboxylase isozyme, inducible [Escherichia coli str.
K-12 substr. MG1655].
ACCESSION NP_415220
VERSION NP_415220.1 GI:16128669
DBLINK Project: 57779
BioProject: PRJNA57779
DBSOURCE REFSEQ: accession NC_000913.2
KEYWORDS .
SOURCE Escherichia coli str. K-12 substr. MG1655
ORGANISM Escherichia coli str. K-12 substr. MG1655
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
Enterobacteriaceae; Escherichia.
REFERENCE 1 (residues 1 to 732)
AUTHORS Riley,M., Abe,T., Arnaud,M.B., Berlyn,M.K., Blattner,F.R.,
Chaudhuri,R.R., Glasner,J.D., Horiuchi,T., Keseler,I.M., Kosuge,T.,
Mori,H., Perna,N.T., Plunkett,G. III, Rudd,K.E., Serres,M.H.,
Thomas,G.H., Thomson,N.R., Wishart,D. and Wanner,B.L.
TITLE Escherichia coli K-12: a cooperatively developed annotation
snapshot--2005
JOURNAL Nucleic Acids Res. 34 (1), 1-9 (2006)
PUBMED 16397293
REMARK Publication Status: Online-Only
REFERENCE 2 (residues 1 to 732)
AUTHORS Blattner,F.R., Plunkett,G. III, Bloch,C.A., Perna,N.T., Burland,V.,
Riley,M., Collado-Vides,J., Glasner,J.D., Rode,C.K., Mayhew,G.F.,
Gregor,J., Davis,N.W., Kirkpatrick,H.A., Goeden,M.A., Rose,D.J.,
Mau,B. and Shao,Y.
TITLE The complete genome sequence of Escherichia coli K-12
JOURNAL Science 277 (5331), 1453-1474 (1997)
PUBMED 9278503
REFERENCE 3 (residues 1 to 732)
AUTHORS Arnaud,M., Berlyn,M.K.B., Blattner,F.R., Galperin,M.Y.,
Glasner,J.D., Horiuchi,T., Kosuge,T., Mori,H., Perna,N.T.,
Plunkett,G. III, Riley,M., Rudd,K.E., Serres,M.H., Thomas,G.H. and
Wanner,B.L.
TITLE Workshop on Annotation of Escherichia coli K-12
JOURNAL Unpublished
REMARK Woods Hole, Mass., on 14-18 November 2003 (sequence corrections)
REFERENCE 4 (residues 1 to 732)
AUTHORS Glasner,J.D., Perna,N.T., Plunkett,G. III, Anderson,B.D.,
Bockhorst,J., Hu,J.C., Riley,M., Rudd,K.E. and Serres,M.H.
TITLE ASAP: Escherichia coli K-12 strain MG1655 version m56
JOURNAL Unpublished
REMARK ASAP download 10 June 2004 (annotation updates)
REFERENCE 5 (residues 1 to 732)
AUTHORS Hayashi,K., Morooka,N., Mori,H. and Horiuchi,T.
TITLE A more accurate sequence comparison between genomes of Escherichia
coli K12 W3110 and MG1655 strains
JOURNAL Unpublished
REMARK GenBank accessions AG613214 to AG613378 (sequence corrections)
REFERENCE 6 (residues 1 to 732)
AUTHORS Perna,N.T.
TITLE Escherichia coli K-12 MG1655 yqiK-rfaE intergenic region, genomic
sequence correction
JOURNAL Unpublished
REMARK GenBank accession AY605712 (sequence corrections)
REFERENCE 7 (residues 1 to 732)
AUTHORS Rudd,K.E.
TITLE A manual approach to accurate translation start site annotation: an
E. coli K-12 case study
JOURNAL Unpublished
REFERENCE 8 (residues 1 to 732)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (04-MAR-2013) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 9 (residues 1 to 732)
AUTHORS Rudd,K.E.
TITLE Direct Submission
JOURNAL Submitted (06-FEB-2013) Department of Biochemistry and Molecular
Biology, University of Miami Miller School of Medicine, 118 Gautier
Bldg., Miami, FL 33136, USA
REMARK Sequence update by submitter
REFERENCE 10 (residues 1 to 732)
AUTHORS Rudd,K.E.
TITLE Direct Submission
JOURNAL Submitted (24-APR-2007) Department of Biochemistry and Molecular
Biology, University of Miami Miller School of Medicine, 118 Gautier
Bldg., Miami, FL 33136, USA
REMARK Annotation update from ecogene.org as a multi-database
collaboration
REFERENCE 11 (residues 1 to 732)
AUTHORS Plunkett,G. III.
TITLE Direct Submission
JOURNAL Submitted (07-FEB-2006) Laboratory of Genetics, University of
Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
REMARK Protein updates by submitter
REFERENCE 12 (residues 1 to 732)
AUTHORS Plunkett,G. III.
TITLE Direct Submission
JOURNAL Submitted (10-JUN-2004) Laboratory of Genetics, University of
Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
REMARK Sequence update by submitter
REFERENCE 13 (residues 1 to 732)
AUTHORS Plunkett,G. III.
TITLE Direct Submission
JOURNAL Submitted (13-OCT-1998) Laboratory of Genetics, University of
Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
REFERENCE 14 (residues 1 to 732)
AUTHORS Blattner,F.R. and Plunkett,G. III.
TITLE Direct Submission
JOURNAL Submitted (02-SEP-1997) Laboratory of Genetics, University of
Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
REFERENCE 15 (residues 1 to 732)
AUTHORS Blattner,F.R. and Plunkett,G. III.
TITLE Direct Submission
JOURNAL Submitted (16-JAN-1997) Laboratory of Genetics, University of
Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to AAC73787.
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..732
/organism="Escherichia coli str. K-12 substr. MG1655"
/strain="K-12"
/sub_strain="MG1655"
/db_xref="taxon:511145"
Protein 1..732
/product="ornithine decarboxylase isozyme, inducible"
/EC_number="4.1.1.17"
/function="enzyme; Central intermediary metabolism:
Polyamine biosynthesis"
/calculated_mol_wt=82285
Region 1..719
/region_name="PRK13578"
/note="ornithine decarboxylase; Provisional"
/db_xref="CDD:237434"
Region 4..103
/region_name="OKR_DC_1_N"
/note="Orn/Lys/Arg decarboxylase, N-terminal domain;
pfam03709"
/db_xref="CDD:217683"
Region 110..435
/region_name="Orn_deC_like"
/note="Ornithine decarboxylase family. This family belongs
to pyridoxal phosphate (PLP)-dependent aspartate
aminotransferase superfamily (fold I). The major groups in
this CD corresponds to ornithine decarboxylase (ODC),
arginine decarboxylase (ADC) and lysine...; cd00615"
/db_xref="CDD:99739"
Site order(158,163,171,196..198,200..201,204,208..210,212..213,
224..225,354..355,358..362,387..388,390..392,394,401,404,
407,420..421)
/site_type="other"
/note="homodimer interface [polypeptide binding]"
/db_xref="CDD:99739"
Site order(198..200,224,226,289,317,319..320,352,354..355)
/site_type="other"
/note="pyridoxal 5'-phosphate binding site [chemical
binding]"
/db_xref="CDD:99739"
Site 355
/site_type="active"
/note="catalytic residue [active]"
/db_xref="CDD:99739"
Region 576..709
/region_name="OKR_DC_1_C"
/note="Orn/Lys/Arg decarboxylase, C-terminal domain;
pfam03711"
/db_xref="CDD:112521"
CDS 1..732
/gene="speF"
/locus_tag="b0693"
/gene_synonym="ECK0681; JW0680"
/coded_by="complement(NC_000913.2:717485..719683)"
/GO_process="GO:0006596 - polyamine biosynthetic process"
/transl_table=11
/db_xref="ASAP:ABE-0002362"
/db_xref="UniProtKB/Swiss-Prot:P24169"
/db_xref="EcoGene:EG10964"
/db_xref="GeneID:945297"
ORIGIN
1 msklkiavsd scpdcfttqr eciyinesrn idvaaivlsl ndvtcgklde idatgygipv
61 fiatenqerv paeylprisg vfencesrre fygrqletaa shyetqlrpp ffralvdyvn
121 qgnsafdcpg hqggeffrrh pagnqfveyf gealfradlc nadvamgdll ihegapciaq
181 qhaakvfnad ktyfvlngts ssnkvvlnal ltpgdlvlfd rnnhksnhhg allqagatpv
241 yletarnpyg figgidahcf eesylrelia evapqrakea rpfrlaviql gtydgtiyna
301 rqvvdkighl cdyilfdsaw vgyeqfipmm adcspllldl nendpgilvt qsvhkqqagf
361 sqtsqihkkd shikgqqryv phkrmnnafm mhastspfyp lfaalninak mhegvsgrnm
421 wmdcvvngin arklildncq hirpfvpelv dgkpwqsyet aqiavdlrff qfvpgehwhs
481 fegyaenqyf vdpckllltt pgidarngey eafgvpatil anflrengvv pekcdlnsil
541 flltpaedma klqqlvallv rfekllesda plaevlpsiy kqheeryagy tlrqlcqemh
601 dlyarhnvkq lqkemfrkeh fprvsmnpqe anyaylrgev elvrlpdaeg riaaegalpy
661 ppgvlcvvpg eiwggavlry fsaleeginl lpgfapelqg vyieehdgrk qvwcyvikpr
721 daqstllkge kl
//
