LOCUS NP_669265 341 aa linear BCT 25-FEB-2013
DEFINITION DNA-binding transcriptional repressor PurR [Yersinia pestis
KIM10+].
ACCESSION NP_669265
VERSION NP_669265.1 GI:22125842
DBLINK Project: 57875
BioProject: PRJNA57875
DBSOURCE REFSEQ: accession NC_004088.1
KEYWORDS .
SOURCE Yersinia pestis KIM10+
ORGANISM Yersinia pestis KIM10+
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
Enterobacteriaceae; Yersinia.
REFERENCE 1 (residues 1 to 341)
AUTHORS Deng,W., Burland,V., Plunkett,G. III, Boutin,A., Mayhew,G.F.,
Liss,P., Perna,N.T., Rose,D.J., Mau,B., Zhou,S., Schwartz,D.C.,
Fetherston,J.D., Lindler,L.E., Brubaker,R.R., Plana,G.V.,
Straley,S.C., McDonough,K.A., Nilles,M.L., Matson,J.S.,
Blattner,F.R. and Perry,R.D.
TITLE Genome Sequence of Yersinia pestis KIM
JOURNAL J. Bacteriol. 184 (16), 4601-4611 (2002)
PUBMED 12142430
REFERENCE 2 (residues 1 to 341)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (10-SEP-2004) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (residues 1 to 341)
AUTHORS Deng,W., Burland,V., Plunkett,G. III, Boutin,A., Mayhew,G.F.,
Liss,P., Perna,N.T., Rose,D.J., Mau,B., Zhou,S., Schwartz,D.C.,
Fetherston,J.D., Lindler,L.E., Brubaker,R.R., Plana,G.V.,
Straley,S.C., McDonough,K.A., Nilles,M.L., Matson,J.S.,
Blattner,F.R. and Perry,R.D.
TITLE Direct Submission
JOURNAL Submitted (21-FEB-2002) Genetics, University of Wisconsin, 445
Henry Mall, Madison, WI 53706, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to AAM85516.
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..341
/organism="Yersinia pestis KIM10+"
/strain="KIM"
/sub_strain="KIM10+"
/db_xref="taxon:187410"
Protein 1..341
/product="DNA-binding transcriptional repressor PurR"
/function="regulator; purine ribonucleotide biosynthesis"
/calculated_mol_wt=37708
Region 1..341
/region_name="PRK10703"
/note="DNA-binding transcriptional repressor PurR;
Provisional"
/db_xref="CDD:182662"
Region 5..55
/region_name="HTH_LacI"
/note="Helix-turn-helix (HTH) DNA binding domain of the
LacI family of transcriptional regulators; cd01392"
/db_xref="CDD:143331"
Site order(5,13..17,19..20,23,28..29,32,45,48,51..52,54..55)
/site_type="DNA binding"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:143331"
Site 45..54
/site_type="other"
/note="domain linker motif"
/db_xref="CDD:143331"
Region 61..330
/region_name="PBP1_PurR"
/note="Ligand-binding domain of purine repressor, PurR,
which functions as the master regulatory protein of de
novo purine nucleotide biosynthesis in Escherichia coli;
cd06275"
/db_xref="CDD:107270"
Site order(70,86,90,92..94,107,114,224,252,256,260,279,
281..282,329)
/site_type="other"
/note="dimerization interface [polypeptide binding]"
/db_xref="CDD:107270"
Site order(73,190,192,196,221,275)
/site_type="other"
/note="ligand binding site [chemical binding]"
/db_xref="CDD:107270"
CDS 1..341
/gene="purR"
/locus_tag="y1950"
/coded_by="complement(NC_004088.1:2152199..2153224)"
/note="binds to the purF operator and coregulates other
genes for de novo purine nucleotide synthesis; is involved
in regulation of purB, purC, purEK, purHD, purL, purMN and
guaBA expression; binds hypoxanthine and guanine as
inducers"
/transl_table=11
/db_xref="GeneID:1146897"
ORIGIN
1 matikdvakh agvstttvsh vinktrfvae ntkaavwaai kelhyspsav arslkvnhtk
61 sigllatsse apyfaeviea venscyskgy tlilcnshnn ldkqkaylam laqkrvdgll
121 vmcseypdql lgmledyrni pmvvmdwgta rgdftdsiid nafeggylag rylierghrd
181 igaipgqlar ntgggrhqgf lkaleeanip vreewivqgd fepesgykam hqiltqkhrp
241 tavfcggdim amgaicaade lglrvpqdis vigydnvrna ryfspaltti hqpkerlget
301 afamlldriv skredpqtie vhpklverrs vadgpfrdyr r
//
