LOCUS WP_005238605 446 aa linear BCT 12-SEP-2023
DEFINITION MULTISPECIES: 4-aminobutyrate--2-oxoglutarate transaminase
[Rhodococcus].
ACCESSION WP_005238605
VERSION WP_005238605.1
KEYWORDS RefSeq.
SOURCE Rhodococcus
ORGANISM Rhodococcus
Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
Nocardiaceae.
REFERENCE 1 (residues 1 to 446)
AUTHORS Bruce,H., Nguyen Tuan,A., Mangas Sanchez,J., Leese,C., Hopwood,J.,
Hyde,R., Hart,S., Turkenburg,J.P. and Grogan,G.
TITLE Structures of a gamma-aminobutyrate (GABA) transaminase from the
s-triazine-degrading organism Arthrobacter aurescens TC1 in complex
with PLP and with its external aldimine PLP-GABA adduct
JOURNAL Acta Crystallogr Sect F Struct Biol Cryst Commun 68 (Pt 10),
1175-1180 (2012)
PUBMED 23027742
COMMENT REFSEQ: This record represents a single, non-redundant, protein
sequence which may be annotated on many different RefSeq genomes
from the same, or different, species.
##Evidence-For-Name-Assignment-START##
Evidence Category :: HMM
Evidence Accession :: TIGR00700.1
Evidence Source :: JCVI
##Evidence-For-Name-Assignment-END##
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..446
/organism="Rhodococcus"
/db_xref="taxon:1827"
gene 1..446
/gene="gabT"
Protein 1..446
/product="4-aminobutyrate--2-oxoglutarate transaminase"
/EC_number="2.6.1.19"
/GO_function="GO:0003867 - 4-aminobutyrate transaminase
activity [Evidence IEA]"
/GO_process="GO:0009450 - gamma-aminobutyric acid
catabolic process [Evidence IEA]"
/calculated_mol_wt=46770
Region 5..445
/region_name="PRK06058"
/note="4-aminobutyrate--2-oxoglutarate transaminase"
/db_xref="CDD:235685"
Site order(129..131,157..158,160,228,261,263..264,290)
/site_type="active"
/note="inhibitor-cofactor binding pocket [active]"
/db_xref="CDD:99735"
Site order(130..131,157..158,228,261,264,290)
/site_type="other"
/note="pyridoxal 5'-phosphate binding site [chemical
binding]"
/db_xref="CDD:99735"
Site 290
/site_type="active"
/note="catalytic residue [active]"
/db_xref="CDD:99735"
ORIGIN
1 mndiqyrlpq kralvtelpg pksaaltarr ratvaagvgs svpvyaadad ggvvvdvdgn
61 slidlgsgia vtsvgasdpa vaeavreqvg hfthtcfmvt pyegyvrvae elaaltpgdh
121 ekrtvlfnsg aeavenaikv arlatgrdav vafdhayhgr tnltmaltak smpykahfgp
181 fapevyrlpm sypyrdqdgl tgeqaaqrai sqmekqigad slaaiiiepi qgeggfivpa
241 egflptlvnw arangvvfia devqtgfsrt gawfacehee ivpdiitmak gmaggmplsa
301 itgraelldk vhpgglggty ggnpvacaaa laaidsmrkf dlparaqhig dlalprlkal
361 aadvgvigdv rgrgamlame fvkpgtdepd aeltkaiaah aleqgvillt cgtygnvirl
421 lpplvisddl lddaltvieq ivrslv
//