GenomeNet

Database: RefSeq
Entry: WP_005238605
LinkDB: WP_005238605
Original site: WP_005238605 
LOCUS       WP_005238605             446 aa            linear   BCT 12-SEP-2023
DEFINITION  MULTISPECIES: 4-aminobutyrate--2-oxoglutarate transaminase
            [Rhodococcus].
ACCESSION   WP_005238605
VERSION     WP_005238605.1
KEYWORDS    RefSeq.
SOURCE      Rhodococcus
  ORGANISM  Rhodococcus
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae.
REFERENCE   1  (residues 1 to 446)
  AUTHORS   Bruce,H., Nguyen Tuan,A., Mangas Sanchez,J., Leese,C., Hopwood,J.,
            Hyde,R., Hart,S., Turkenburg,J.P. and Grogan,G.
  TITLE     Structures of a gamma-aminobutyrate (GABA) transaminase from the
            s-triazine-degrading organism Arthrobacter aurescens TC1 in complex
            with PLP and with its external aldimine PLP-GABA adduct
  JOURNAL   Acta Crystallogr Sect F Struct Biol Cryst Commun 68 (Pt 10),
            1175-1180 (2012)
   PUBMED   23027742
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00700.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Rhodococcus"
                     /db_xref="taxon:1827"
     gene            1..446
                     /gene="gabT"
     Protein         1..446
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /EC_number="2.6.1.19"
                     /GO_function="GO:0003867 - 4-aminobutyrate transaminase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009450 - gamma-aminobutyric acid
                     catabolic process [Evidence IEA]"
                     /calculated_mol_wt=46770
     Region          5..445
                     /region_name="PRK06058"
                     /note="4-aminobutyrate--2-oxoglutarate transaminase"
                     /db_xref="CDD:235685"
     Site            order(129..131,157..158,160,228,261,263..264,290)
                     /site_type="active"
                     /note="inhibitor-cofactor binding pocket [active]"
                     /db_xref="CDD:99735"
     Site            order(130..131,157..158,228,261,264,290)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99735"
     Site            290
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
ORIGIN      
        1 mndiqyrlpq kralvtelpg pksaaltarr ratvaagvgs svpvyaadad ggvvvdvdgn
       61 slidlgsgia vtsvgasdpa vaeavreqvg hfthtcfmvt pyegyvrvae elaaltpgdh
      121 ekrtvlfnsg aeavenaikv arlatgrdav vafdhayhgr tnltmaltak smpykahfgp
      181 fapevyrlpm sypyrdqdgl tgeqaaqrai sqmekqigad slaaiiiepi qgeggfivpa
      241 egflptlvnw arangvvfia devqtgfsrt gawfacehee ivpdiitmak gmaggmplsa
      301 itgraelldk vhpgglggty ggnpvacaaa laaidsmrkf dlparaqhig dlalprlkal
      361 aadvgvigdv rgrgamlame fvkpgtdepd aeltkaiaah aleqgvillt cgtygnvirl
      421 lpplvisddl lddaltvieq ivrslv
//
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