LOCUS       WP_008983784             297 aa            linear   BCT 10-OCT-2019
DEFINITION  3-hydroxyisobutyrate dehydrogenase [Alishewanella agri].
ACCESSION   WP_008983784
VERSION     WP_008983784.1
KEYWORDS    RefSeq.
SOURCE      Alishewanella agri
  ORGANISM  Alishewanella agri
            Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
            Alteromonadaceae; Alishewanella.
REFERENCE   1  (residues 1 to 297)
  AUTHORS   Hawes,J.W., Harper,E.T., Crabb,D.W. and Harris,R.A.
  TITLE     Structural and mechanistic similarities of 6-phosphogluconate and
            3-hydroxyisobutyrate dehydrogenases reveal a new enzyme family, the
            3-hydroxyacid dehydrogenases
  JOURNAL   FEBS Lett. 389 (3), 263-267 (1996)
   PUBMED   8766712
REFERENCE   2  (residues 1 to 297)
  AUTHORS   Steele,M.I., Lorenz,D., Hatter,K., Park,A. and Sokatch,J.R.
  TITLE     Characterization of the mmsAB operon of Pseudomonas aeruginosa PAO
            encoding methylmalonate-semialdehyde dehydrogenase and
            3-hydroxyisobutyrate dehydrogenase
  JOURNAL   J. Biol. Chem. 267 (19), 13585-13592 (1992)
   PUBMED   1339433
REFERENCE   3  (residues 1 to 297)
  AUTHORS   Rougraff,P.M., Zhang,B., Kuntz,M.J., Harris,R.A. and Crabb,D.W.
  TITLE     Cloning and sequence analysis of a cDNA for 3-hydroxyisobutyrate
            dehydrogenase. Evidence for its evolutionary relationship to other
            pyridine nucleotide-dependent dehydrogenases
  JOURNAL   J. Biol. Chem. 264 (10), 5899-5903 (1989)
   PUBMED   2647728
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01692.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Alishewanella agri"
                     /db_xref="taxon:553384"
     gene            1..297
                     /gene="mmsB"
     Protein         1..297
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /EC_number="1.1.1.31"
                     /GO_function="GO:0008442 - 3-hydroxyisobutyrate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0006574 - valine catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=30235
     Region          6..289
                     /region_name="garR"
                     /note="tartronate semialdehyde reductase; Provisional;
                     cl42929"
                     /db_xref="CDD:456274"
ORIGIN      
        1 makvafiglg nmggpmavnl vkaghqvaaf dlsanalaqv kaegaavass aadavagadf
       61 vismlpaakh vlslylgeqg iathidkkal vidcstidad sarklgaala eqdlafidap
      121 vsggvggaka gtltfivggs dadferaktv lgnmgknlfh agavgagqva kicnnmllsi
      181 lmvgtsealq mgidngldpk vlseimlkss grnwtlelyn pcpdvlpnvp ssngyqggfm
      241 vdlmvkdlgl aleaslqsgs stplgalars lyvahqragn gkldfssift afekvkn
//