LOCUS       WP_015824467             469 aa            linear   BCT 12-DEC-2023
DEFINITION  MULTISPECIES: 3-isopropylmalate dehydratase large subunit
            [Methylorubrum].
ACCESSION   WP_015824467
VERSION     WP_015824467.1
KEYWORDS    RefSeq.
SOURCE      Methylorubrum
  ORGANISM  Methylorubrum
            Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
            Methylobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00170.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Methylorubrum"
                     /db_xref="taxon:2282523"
     gene            1..469
                     /gene="leuC"
     Protein         1..469
                     /product="3-isopropylmalate dehydratase large subunit"
                     /EC_number="4.2.1.33"
                     /function="1.4 : Pyruvate family"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=50475
     Region          3..467
                     /region_name="PRK05478"
                     /note="3-isopropylmalate dehydratase large subunit"
                     /db_xref="CDD:235490"
     Site            order(35,38,130..131,413,432,437)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:153133"
     Site            order(132,349,409,412..413,431)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:153133"
ORIGIN      
        1 mtaprtlydk iwddhvvdve pdgsallyid rhlvhevtsp qafeglrvag rtvraphktl
       61 avvdhnvqts drskgiedpe srtqlealae nvrdfgiefy daldqrqgiv hiigpeqgft
      121 lpgqtivcgd shtsthgafg alahgigtse vehvlatqtl iqrkaknmrv tvdgtlprgv
      181 sakdivlaii geigtaggtg hvieyageai ralsmegrmt icnmsiegga ragmvapdet
      241 tyayvngrpk apkgaafdaa rryweslatd egahfdreir ldaanlpplv swgtspediv
      301 silgtvpdpa qiadenkrqs kekalaymgl tpgtrmtdvt ldrvfigsct ngriedlriv
      361 akmvegrkvh dsvsamvvpg sglvkaqaea egidrilkda gfdwrepgcs mclgmnpdkl
      421 rpgercasts nrnfegrqgp rgrthlvspa maaaaavagr fvdirewrg
//