LOCUS WP_015880047 220 aa linear BCT 04-JUL-2022
DEFINITION carbonate dehydratase [Tolumonas auensis].
ACCESSION WP_015880047
VERSION WP_015880047.1
KEYWORDS RefSeq.
SOURCE Tolumonas auensis
ORGANISM Tolumonas auensis
Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
Aeromonadaceae; Tolumonas.
REFERENCE 1 (residues 1 to 220)
AUTHORS Langereis,J.D., Zomer,A., Stunnenberg,H.G., Burghout,P. and
Hermans,P.W.
TITLE Nontypeable Haemophilus influenzae carbonic anhydrase is important
for environmental and intracellular survival
JOURNAL J Bacteriol 195 (12), 2737-2746 (2013)
PUBMED 23564172
COMMENT REFSEQ: This record represents a single, non-redundant, protein
sequence which may be annotated on many different RefSeq genomes
from the same, or different, species.
##Evidence-For-Name-Assignment-START##
Evidence Category :: HMM
Evidence Accession :: NF007756.0
Evidence Source :: NCBI Protein Cluster (PRK)
Source Identifier :: PRK10437
##Evidence-For-Name-Assignment-END##
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..220
/organism="Tolumonas auensis"
/db_xref="taxon:43948"
gene 1..220
/gene="can"
Protein 1..220
/product="carbonate dehydratase"
/GO_function="GO:0004089 - carbonate dehydratase activity
[Evidence IEA]"
/GO_function="GO:0008270 - zinc ion binding [Evidence
IEA]"
/GO_process="GO:0015976 - carbon utilization [Evidence
IEA]"
/calculated_mol_wt=25201
Region 11..192
/region_name="beta_CA_cladeA"
/note="Carbonic anhydrases (CA) are zinc-containing
enzymes that catalyze the reversible hydration of carbon
dioxide in a two-step mechanism in which the nucleophilic
attack of a zinc-bound hydroxide ion on carbon dioxide is
followed by the regeneration of an...; cd00883"
/db_xref="CDD:238448"
Site order(33,35,42,44..46,58,61,83,88,98,101,182)
/site_type="active"
/note="active site clefts [active]"
/db_xref="CDD:238448"
Site order(42,44,98,101)
/site_type="other"
/note="zinc binding site [ion binding]"
/db_xref="CDD:238448"
Site order(43..46,48,50..51,53,58..60,62,64,78..79,82..83,119,
182,184..185,187,189)
/site_type="other"
/note="dimer interface [polypeptide binding]"
/db_xref="CDD:238448"
ORIGIN
1 mkllkqlftq nrlwaeqika edpkffekla sqqapeylwi gcsdsrvpan ellgllpgdv
61 fvhrnvanlv vhtdfnclsv iqyavevlkv khiivcghyh cggviaamgn keyglidnwl
121 rnikdihyky qaqmeeiede herqdylcel nvleqvanvc ytsivqnawr rgqplavhgw
181 iydvkdgllr dlditvnale qipevyrssc qkvsalhhsk
//