LOCUS       WP_044979082             433 aa            linear   BCT 10-OCT-2019
DEFINITION  phosphoenolpyruvate mutase [Treponema putidum].
ACCESSION   WP_044979082
VERSION     WP_044979082.1
KEYWORDS    RefSeq.
SOURCE      Treponema putidum
  ORGANISM  Treponema putidum
            Bacteria; Spirochaetota; Spirochaetia; Spirochaetales;
            Treponemataceae; Treponema.
REFERENCE   1  (residues 1 to 433)
  AUTHORS   Sarkar,M., Hamilton,C.J. and Fairlamb,A.H.
  TITLE     Properties of phosphoenolpyruvate mutase, the first enzyme in the
            aminoethylphosphonate biosynthetic pathway in Trypanosoma cruzi
  JOURNAL   J. Biol. Chem. 278 (25), 22703-22708 (2003)
   PUBMED   12672809
REFERENCE   2  (residues 1 to 433)
  AUTHORS   Coyne,M.J., Kalka-Moll,W., Tzianabos,A.O., Kasper,D.L. and
            Comstock,L.E.
  TITLE     Bacteroides fragilis NCTC9343 produces at least three distinct
            capsular polysaccharides: cloning, characterization, and
            reassignment of polysaccharide B and C biosynthesis loci
  JOURNAL   Infect. Immun. 68 (11), 6176-6181 (2000)
   PUBMED   11035722
REFERENCE   3  (residues 1 to 433)
  AUTHORS   Schwartz,D., Recktenwald,J., Pelzer,S. and Wohlleben,W.
  TITLE     Isolation and characterization of the PEP-phosphomutase and the
            phosphonopyruvate decarboxylase genes from the phosphinothricin
            tripeptide producer Streptomyces viridochromogenes Tu494
  JOURNAL   FEMS Microbiol. Lett. 163 (2), 149-157 (1998)
   PUBMED   9673017
REFERENCE   4  (residues 1 to 433)
  AUTHORS   Hidaka,T., Hidaka,M. and Seto,H.
  TITLE     Studies on the biosynthesis of bialaphos (SF-1293). 14. Nucleotide
            sequence of phosphoenolpyruvate phosphomutase gene isolated from a
            bialaphos producing organism, Streptomyces hygroscopicus, and its
            expression in Streptomyces lividans
  JOURNAL   J. Antibiot. 45 (12), 1977-1980 (1992)
   PUBMED   1337066
REFERENCE   5  (residues 1 to 433)
  AUTHORS   Seidel,H.M., Pompliano,D.L. and Knowles,J.R.
  TITLE     Phosphonate biosynthesis: molecular cloning of the gene for
            phosphoenolpyruvate mutase from Tetrahymena pyriformis and
            overexpression of the gene product in Escherichia coli
  JOURNAL   Biochemistry 31 (9), 2598-2608 (1992)
   PUBMED   1547241
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02320.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Treponema putidum"
                     /db_xref="taxon:221027"
     gene            1..433
                     /gene="aepX"
     Protein         1..433
                     /product="phosphoenolpyruvate mutase"
                     /EC_number="5.4.2.9"
                     /GO_function="GO:0050188 - phosphoenolpyruvate mutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /calculated_mol_wt=48348
     Region          3..138
                     /region_name="nt_trans"
                     /note="nucleotidyl transferase superfamily; cl00015"
                     /db_xref="CDD:444652"
     Site            order(15..18,127..130)
                     /site_type="active"
                     /db_xref="CDD:173912"
     Site            order(15,18,128)
                     /site_type="other"
                     /note="nucleotide binding site [chemical binding]"
                     /db_xref="CDD:173912"
     Site            15..18
                     /site_type="other"
                     /note="HIGH motif"
                     /db_xref="CDD:173912"
     Site            127..130
                     /site_type="other"
                     /note="KMSKS motif"
                     /db_xref="CDD:173912"
     Region          149..433
                     /region_name="PEP_mutase"
                     /note="phosphoenolpyruvate mutase; TIGR02320"
                     /db_xref="CDD:274077"
ORIGIN      
        1 mkkkvylglt gdiihpgiin iinegkkygh liiglltdta ivshkrlpyl syeqrkqvve
       61 nikgvsevip qedwsyipnl kklkpdfiih gddwksgsls kirdevievm kewggeviev
      121 pytkginssa lasnmhsigt tpevrmktlr rlieakpivr imeahsglsg liienlevqk
      181 ddgvhrydgm wsssltdsts kgkpdieavd lttrlqsltd ilecttkpii ydgdtggkte
      241 hfvftvrtle rngvsaiiie dkvglkknsl fgteakqela svedfchkis egkkaqvtkd
      301 fmiiarlesl iaghsvdeal erafayvkag adgvmihske khgndikefc erfrkeyekv
      361 pivlvpttyn qftekelaaw ganiiiyanh mlrasypaml kaaktileae rslevndmcl
      421 sikqilelip gtk
//