LOCUS XP_002105667 384 aa linear INV 05-AUG-2008
DEFINITION GD16217 [Drosophila simulans].
ACCESSION XP_002105667
VERSION XP_002105667.1 GI:195575400
DBSOURCE REFSEQ: accession XM_002105631.1
KEYWORDS .
SOURCE Drosophila simulans
ORGANISM Drosophila simulans
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
REFERENCE 1 (residues 1 to 384)
AUTHORS Clark,A.G., Eisen,M.B., Smith,D.R., Bergman,C.M., Oliver,B.,
Markow,T.A., Kaufman,T.C., Kellis,M., Gelbart,W., Iyer,V.N.,
Pollard,D.A., Sackton,T.B., Larracuente,A.M., Singh,N.D.,
Abad,J.P., Abt,D.N., Adryan,B., Aguade,M., Akashi,H.,
Anderson,W.W., Aquadro,C.F., Ardell,D.H., Arguello,R.,
Artieri,C.G., Barbash,D.A., Barker,D., Barsanti,P., Batterham,P.,
Batzoglou,S., Begun,D., Bhutkar,A., Blanco,E., Bosak,S.A.,
Bradley,R.K., Brand,A.D., Brent,M.R., Brooks,A.N., Brown,R.H.,
Butlin,R.K., Caggese,C., Calvi,B.R., Bernardo de Carvalho,A.,
Caspi,A., Castrezana,S., Celniker,S.E., Chang,J.L., Chapple,C.,
Chatterji,S., Chinwalla,A., Civetta,A., Clifton,S.W., Comeron,J.M.,
Costello,J.C., Coyne,J.A., Daub,J., David,R.G., Delcher,A.L.,
Delehaunty,K., Do,C.B., Ebling,H., Edwards,K., Eickbush,T.,
Evans,J.D., Filipski,A., Findeiss,S., Freyhult,E., Fulton,L.,
Fulton,R., Garcia,A.C., Gardiner,A., Garfield,D.A., Garvin,B.E.,
Gibson,G., Gilbert,D., Gnerre,S., Godfrey,J., Good,R., Gotea,V.,
Gravely,B., Greenberg,A.J., Griffiths-Jones,S., Gross,S., Guigo,R.,
Gustafson,E.A., Haerty,W., Hahn,M.W., Halligan,D.L., Halpern,A.L.,
Halter,G.M., Han,M.V., Heger,A., Hillier,L., Hinrichs,A.S.,
Holmes,I., Hoskins,R.A., Hubisz,M.J., Hultmark,D., Huntley,M.A.,
Jaffe,D.B., Jagadeeshan,S., Jeck,W.R., Johnson,J., Jones,C.D.,
Jordan,W.C., Karpen,G.H., Kataoka,E., Keightley,P.D.,
Kheradpour,P., Kirkness,E.F., Koerich,L.B., Kristiansen,K.,
Kudrna,D., Kulathinal,R.J., Kumar,S., Kwok,R., Lander,E.,
Langley,C.H., Lapoint,R., Lazzaro,B.P., Lee,S.J., Levesque,L.,
Li,R., Lin,C.F., Lin,M.F., Lindblad-Toh,K., Llopart,A., Long,M.,
Low,L., Lozovsky,E., Lu,J., Luo,M., Machado,C.A., Makalowski,W.,
Marzo,M., Matsuda,M., Matzkin,L., McAllister,B., McBride,C.S.,
McKernan,B., McKernan,K., Mendez-Lago,M., Minx,P.,
Mollenhauer,M.U., Montooth,K., Mount,S.M., Mu,X., Myers,E.,
Negre,B., Newfeld,S., Nielsen,R., Noor,M.A., O'Grady,P.,
Pachter,L., Papaceit,M., Parisi,M.J., Parisi,M., Parts,L.,
Pedersen,J.S., Pesole,G., Phillippy,A.M., Ponting,C.P., Pop,M.,
Porcelli,D., Powell,J.R., Prohaska,S., Pruitt,K., Puig,M.,
Quesneville,H., Ram,K.R., Rand,D., Rasmussen,M.D., Reed,L.K.,
Reenan,R., Reily,A., Remington,K.A., Rieger,T.T., Ritchie,M.G.,
Robin,C., Rogers,Y.H., Rohde,C., Rozas,J., Rubenfield,M.J.,
Ruiz,A., Russo,S., Salzberg,S.L., Sanchez-Gracia,A., Saranga,D.J.,
Sato,H., Schaeffer,S.W., Schatz,M.C., Schlenke,T., Schwartz,R.,
Segarra,C., Singh,R.S., Sirot,L., Sirota,M., Sisneros,N.B.,
Smith,C.D., Smith,T.F., Spieth,J., Stage,D.E., Stark,A.,
Stephan,W., Strausberg,R.L., Strempel,S., Sturgill,D., Sutton,G.,
Sutton,G.G., Tao,W., Teichmann,S., Tobari,Y.N., Tomimura,Y.,
Tsolas,J.M., Valente,V.L., Venter,E., Venter,J.C., Vicario,S.,
Vieira,F.G., Vilella,A.J., Villasante,A., Walenz,B., Wang,J.,
Wasserman,M., Watts,T., Wilson,D., Wilson,R.K., Wing,R.A.,
Wolfner,M.F., Wong,A., Wong,G.K., Wu,C.I., Wu,G., Yamamoto,D.,
Yang,H.P., Yang,S.P., Yorke,J.A., Yoshida,K., Zdobnov,E., Zhang,P.,
Zhang,Y., Zimin,A.V., Baldwin,J., Abdouelleil,A., Abdulkadir,J.,
Abebe,A., Abera,B., Abreu,J., Acer,S.C., Aftuck,L., Alexander,A.,
An,P., Anderson,E., Anderson,S., Arachi,H., Azer,M.,
Bachantsang,P., Barry,A., Bayul,T., Berlin,A., Bessette,D.,
Bloom,T., Blye,J., Boguslavskiy,L., Bonnet,C., Boukhgalter,B.,
Bourzgui,I., Brown,A., Cahill,P., Channer,S., Cheshatsang,Y.,
Chuda,L., Citroen,M., Collymore,A., Cooke,P., Costello,M.,
D'Aco,K., Daza,R., De Haan,G., DeGray,S., DeMaso,C., Dhargay,N.,
Dooley,K., Dooley,E., Doricent,M., Dorje,P., Dorjee,K., Dupes,A.,
Elong,R., Falk,J., Farina,A., Faro,S., Ferguson,D., Fisher,S.,
Foley,C.D., Franke,A., Friedrich,D., Gadbois,L., Gearin,G.,
Gearin,C.R., Giannoukos,G., Goode,T., Graham,J., Grandbois,E.,
Grewal,S., Gyaltsen,K., Hafez,N., Hagos,B., Hall,J., Henson,C.,
Hollinger,A., Honan,T., Huard,M.D., Hughes,L., Hurhula,B.,
Husby,M.E., Kamat,A., Kanga,B., Kashin,S., Khazanovich,D.,
Kisner,P., Lance,K., Lara,M., Lee,W., Lennon,N., Letendre,F.,
LeVine,R., Lipovsky,A., Liu,X., Liu,J., Liu,S., Lokyitsang,T.,
Lokyitsang,Y., Lubonja,R., Lui,A., MacDonald,P., Magnisalis,V.,
Maru,K., Matthews,C., McCusker,W., McDonough,S., Mehta,T.,
Meldrim,J., Meneus,L., Mihai,O., Mihalev,A., Mihova,T.,
Mittelman,R., Mlenga,V., Montmayeur,A., Mulrain,L., Navidi,A.,
Naylor,J., Negash,T., Nguyen,T., Nguyen,N., Nicol,R., Norbu,C.,
Norbu,N., Novod,N., O'Neill,B., Osman,S., Markiewicz,E.,
Oyono,O.L., Patti,C., Phunkhang,P., Pierre,F., Priest,M.,
Raghuraman,S., Rege,F., Reyes,R., Rise,C., Rogov,P., Ross,K.,
Ryan,E., Settipalli,S., Shea,T., Sherpa,N., Shi,L., Shih,D.,
Sparrow,T., Spaulding,J., Stalker,J., Stange-Thomann,N.,
Stavropoulos,S., Stone,C., Strader,C., Tesfaye,S., Thomson,T.,
Thoulutsang,Y., Thoulutsang,D., Topham,K., Topping,I., Tsamla,T.,
Vassiliev,H., Vo,A., Wangchuk,T., Wangdi,T., Weiand,M.,
Wilkinson,J., Wilson,A., Yadav,S., Young,G., Yu,Q., Zembek,L.,
Zhong,D., Zimmer,A., Zwirko,Z., Jaffe,D.B., Alvarez,P.,
Brockman,W., Butler,J., Chin,C., Gnerre,S., Grabherr,M., Kleber,M.,
Mauceli,E. and MacCallum,I.
CONSRTM Drosophila 12 Genomes Consortium
TITLE Evolution of genes and genomes on the Drosophila phylogeny
JOURNAL Nature 450 (7167), 203-218 (2007)
PUBMED 17994087
REFERENCE 2 (residues 1 to 384)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (09-JUN-2008) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave., Cambridge, MA 02138, USA
REFERENCE 3 (residues 1 to 384)
AUTHORS Wilson,R.K.
CONSRTM The Drosophila simulans Sequencing Consortium
TITLE Direct Submission
JOURNAL Submitted (16-AUG-2006) Genome Sequencing Center, Washington
University School of Medicine, 4444 Forest Park Parkway, St. Louis,
MO 63108, USA
COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation
provided by FlyBase. The reference sequence was derived from
EDX15170.
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..384
/organism="Drosophila simulans"
/strain="mixed"
/db_xref="taxon:7240"
/chromosome="3R"
Protein 1..384
/product="Dsim\GD16217-PA"
/name="GD16217 gene product from transcript GD16217-RA"
/note="GD16217; GD16217-PA"
/calculated_mol_wt=43412
Region 28..349
/region_name="Ferrochelatase"
/note="Ferrochelatase; pfam00762"
/db_xref="CDD:189707"
Region 29..190
/region_name="Ferrochelatase_N"
/note="Ferrochelatase, N-terminal domain: Ferrochelatase
(protoheme ferrolyase or HemH) is the terminal enzyme of
the heme biosynthetic pathway. It catalyzes the insertion
of ferrous iron into the protoporphyrin IX ring yielding
protoheme. This enzyme is...; cd03411"
/db_xref="CDD:48638"
Site order(35,82,86,95,99,150,153..156,186,188)
/site_type="other"
/note="C-terminal domain interface [polypeptide binding]"
/db_xref="CDD:48638"
Site order(36,48,52..54,157..158)
/site_type="active"
/db_xref="CDD:48638"
Region 195..332
/region_name="Ferrochelatase_C"
/note="Ferrochelatase, C-terminal domain: Ferrochelatase
(protoheme ferrolyase or HemH) is the terminal enzyme of
the heme biosynthetic pathway. It catalyzes the insertion
of ferrous iron into the protoporphyrin IX ring yielding
protoheme. This enzyme is...; cd00419"
/db_xref="CDD:73203"
Site order(223,228,270,303)
/site_type="active"
/db_xref="CDD:73203"
Site order(234..236,239,243,296,298..300,302,306,332)
/site_type="other"
/note="N-terminal domain interface [polypeptide binding]"
/db_xref="CDD:73203"
CDS 1..384
/gene="Dsim\GD16217"
/locus_tag="Dsim_GD16217"
/gene_synonym="dsim_GLEANR_1645; GD16217"
/coded_by="XM_002105631.1:1..1155"
/db_xref="FLYBASE:FBgn0187845"
/db_xref="GeneID:6730385"
ORIGIN
1 mflhntklcr lasglaggvr hlsgqkpkta ilmlnmggpt htdqvhdyll rimtdrdmiq
61 lpvqsrlgpw iaqrrtpevq kkykeigggs pilkwtelqg qlmceqldri spetaphkhy
121 vgfryvnplt entlaeiend kpervvlfsq ypqyscatsg ssfnsifthy rsndlpsdik
181 wsiidrwgth plliktfaqr irdelakfve tkrndvvilf tahslplkav nrgdaypsei
241 gasvhmvmqe lgqtnpysla wqskvgplpw lapatddaik gyvkqglknf ilvpiafvne
301 hietlheldi eycdelakev gveeirraaa pndhplfida ltnvvadhlk sqqavnpkfl
361 mrcpmcsnpk creskswyrq lcsn
//
