LOCUS       XP_520565                927 aa            linear   PRI 11-APR-2023
DEFINITION  non-lysosomal glucosylceramidase isoform X4 [Pan troglodytes].
ACCESSION   XP_520565
VERSION     XP_520565.1
DBLINK      BioProject: PRJNA945513
DBSOURCE    REFSEQ: accession XM_520565.8
KEYWORDS    RefSeq.
SOURCE      Pan troglodytes (chimpanzee)
  ORGANISM  Pan troglodytes
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Pan.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_072407) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_028858775.1-RS_2023_04
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 04/06/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..927
                     /organism="Pan troglodytes"
                     /isolate="AG18354"
                     /db_xref="taxon:9598"
                     /chromosome="9"
                     /sex="male"
                     /cell_line="AG18354"
                     /cell_type="lymphoblastoid"
                     /tissue_type="blood"
     Protein         1..927
                     /product="non-lysosomal glucosylceramidase isoform X4"
                     /calculated_mol_wt=104580
     Region          166..455
                     /region_name="Glyco_hydr_116N"
                     /note="beta-glucosidase 2, glycosyl-hydrolase family 116
                     N-term; pfam12215"
                     /db_xref="CDD:432405"
     Region          521..884
                     /region_name="DUF608"
                     /note="Glycosyl-hydrolase family 116, catalytic region;
                     pfam04685"
                     /db_xref="CDD:428065"
     CDS             1..927
                     /gene="GBA2"
                     /coded_by="XM_520565.8:526..3309"
                     /db_xref="GeneID:104001058"
                     /db_xref="VGNC:VGNC:8825"
ORIGIN      
        1 mgtqdpgnmg tgvpaseqis cakedpqvyc peetggtkdv qvtdcksped srpqketdcc
       61 npedsgqlmv syegkamgyq vppfgwricl aheftekrkp fqannvslsn mikhigmglr
      121 ylqwwyrktq vekktpfidm insvplrqiy gcplggiggg titrgwrgqf crwqlnpgmy
      181 qhrtviadqf tvclrregqt vyqqvlsler psvlrswnwg lcgyfafyha lyprawtvyq
      241 lpgqnvtltc rqitpilphd yqdsslpvgv fvwdvenegd ealdvsimfs mrnglgggdd
      301 apgglwnepf clersgetvr glllhhptlp npytmavaar vtaattvthi tafdpdstgq
      361 qvwqdllqdg qldsptgqst pthkgvgiag avcvssklrp rgqcrlefsl awdmprimfg
      421 akgqvhyrry trffgqdgda apalshyalc ryteweeris awqspvlddr slpawyksal
      481 fnelyfladg gtvwlevled slpeelgrnm chlrptlrdy grfgylegqe yrmyntydvh
      541 fyasfaliml wpklelslqy dmalatlred ltrrrylmsg vmapvkrrnv iphdigdpdd
      601 epwlrvnayl ihdtadwkdl nlkfvlqvyr dyyltgdqnf lkdmwpvcla vmesemkfdk
      661 dhdgliengg yadqtydgwv ttgpsaycgg lwlaavavmv qmaalcgaqd iqdkfssils
      721 rgqeayerll wngryynyds ssrpqsrsvm sdqcagqwfl kacglgegdt evfptqhvvr
      781 alqtifelnv qafaggamga vngmqphgvp dkssvqsdev wvgvvyglaa tmiqegltwe
      841 gfqtaegcyr tvwerlglaf qtpeaycqqr vfrslaymrp lsiwamqlal qqqqhkkasw
      901 pkveqgtglr tgpmfgpkea manlspe
//