LOCUS       YP_001273806             423 aa            linear   CON 10-JUN-2013
DEFINITION  glutamate-1-semialdehyde aminotransferase [Methanobrevibacter
            smithii ATCC 35061].
ACCESSION   YP_001273806
VERSION     YP_001273806.1  GI:148643293
DBLINK      Project: 58827
            BioProject: PRJNA58827
DBSOURCE    REFSEQ: accession NC_009515.1
KEYWORDS    .
SOURCE      Methanobrevibacter smithii ATCC 35061
  ORGANISM  Methanobrevibacter smithii ATCC 35061
            Archaea; Euryarchaeota; Methanobacteria; Methanobacteriales;
            Methanobacteriaceae; Methanobrevibacter.
REFERENCE   1  (residues 1 to 423)
  AUTHORS   Samuel,B.S., Hansen,E.E., Manchester,J.K., Coutinho,P.M.,
            Henrissat,B., Fulton,R., Latreille,P., Kim,K., Wilson,R.K. and
            Gordon,J.I.
  TITLE     Genomic and metabolic adaptations of Methanobrevibacter smithii to
            the human gut
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 104 (25), 10643-10648 (2007)
   PUBMED   17563350
REFERENCE   2  (residues 1 to 423)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUN-2007) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 423)
  AUTHORS   Samuel,B.S., Hansen,E.E., Manchester,J.K., Coutinho,P.M.,
            Henrissat,B., Fulton,R., Latreille,P., Kim,K., Wilson,R.K. and
            Gordon,J.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-APR-2007) Center for Genome Sciences, Washington
            University, 4444 Forest Park, Saint Louis, MO 63108, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from ABQ87438.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Methanobrevibacter smithii ATCC 35061"
                     /strain="ATCC 35061; PS; DSMZ 861"
                     /db_xref="ATCC:35061"
                     /db_xref="taxon:420247"
                     /note="type strain of Methanobrevibacter smithii"
     Protein         1..423
                     /product="glutamate-1-semialdehyde aminotransferase"
                     /EC_number="5.4.3.8"
                     /calculated_mol_wt=46244
     Region          3..418
                     /region_name="PRK00062"
                     /note="glutamate-1-semialdehyde aminotransferase;
                     Provisional"
                     /db_xref="CDD:234607"
     Region          6..415
                     /region_name="OAT_like"
                     /note="Acetyl ornithine aminotransferase family. This
                     family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). The major
                     groups in this CD correspond to ornithine
                     aminotransferase, acetylornithine aminotransferase;
                     cd00610"
                     /db_xref="CDD:99735"
     Site            order(110..112,138..139,141,198,231,233..234,259)
                     /site_type="inhibition"
                     /note="inhibitor-cofactor binding pocket"
                     /db_xref="CDD:99735"
     Site            order(111..112,138..139,198,231,234,259)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99735"
     Site            259
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
     CDS             1..423
                     /locus_tag="Msm_1233"
                     /coded_by="complement(NC_009515.1:1235225..1236496)"
                     /inference="protein motif:InterPro:IPR004639"
                     /inference="protein motif:InterPro:IPR005814"
                     /note="Converts (S)-4-amino-5-oxopentanoate to
                     5-aminolevulinate during the porphyrin biosynthesis
                     pathway"
                     /transl_table=11
                     /db_xref="InterPro:IPR004639"
                     /db_xref="InterPro:IPR005814"
                     /db_xref="GeneID:5216017"
CONTIG      join(WP_011954373.1:1..423)
ORIGIN      
        1 mfskdlfqes kkfipggvss pvrafepypf fvkkasgski ydvdgnkyid hclaygplil
       61 ghadpkvvre vsnqltigsa ygtpteneii lakevvdrip saemvrfvns ggeatmsair
      121 largftgkdk iikfdgayhg ahdytlvkge pgkscvpdtk gipldtaknt ysvpfndeea
      181 lsdliqkdgd niaclimevv mgnigciepk kgflefvrki teennillif devitgfrla
      241 rggaqeyygv tpdlttmgki vggglpmgaf agkkeimeli apngpvyqag tfsgnpisvq
      301 agistlkqld nqfykdlerk gnflrsniqs iideqgynit pvgcgsmfqi yfnpapvynn
      361 ddahnsdakr flryfrallk egvfippsqf ecnfissahs medltqtaea ievalevafk
      421 kkg
//