LOCUS       YP_031994                418 aa            linear   BCT 21-DEC-2012
DEFINITION  aspartate kinase [Bartonella quintana str. Toulouse].
ACCESSION   YP_031994
VERSION     YP_031994.1  GI:49473952
DBLINK      Project: 57635
            BioProject: PRJNA57635
DBSOURCE    REFSEQ: accession NC_005955.1
KEYWORDS    .
SOURCE      Bartonella quintana str. Toulouse
  ORGANISM  Bartonella quintana str. Toulouse
            Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
            Bartonellaceae; Bartonella.
REFERENCE   1  (residues 1 to 418)
  AUTHORS   Alsmark,C.M., Frank,A.C., Karlberg,E.O., Legault,B.A., Ardell,D.H.,
            Canback,B., Eriksson,A.S., Naslund,A.K., Handley,S.A., Huvet,M., La
            Scola,B., Holmberg,M. and Andersson,S.G.
  TITLE     The louse-borne human pathogen Bartonella quintana is a genomic
            derivative of the zoonotic agent Bartonella henselae
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (26), 9716-9721 (2004)
   PUBMED   15210978
REFERENCE   2  (residues 1 to 418)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-SEP-2004) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 418)
  AUTHORS   Frank,A.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUN-2004) Dept. of Molecular Evolution, Evolutionary
            Biology Centre, Uppsala University, Sweden
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAF25806.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Bartonella quintana str. Toulouse"
                     /strain="Toulouse"
                     /db_xref="taxon:283165"
     Protein         1..418
                     /product="aspartate kinase"
                     /EC_number="2.7.2.4"
                     /calculated_mol_wt=45132
     Region          1..416
                     /region_name="PRK06635"
                     /note="aspartate kinase; Reviewed"
                     /db_xref="CDD:180641"
     Region          3..253
                     /region_name="AAK_AKii-LysC-BS"
                     /note="AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily
                     (AAK), AKii; this CD includes the N-terminal catalytic
                     aspartokinase (AK) domain of the lysine-sensitive
                     aspartokinase isoenzyme AKII of Bacillus subtilis 168, and
                     the lysine plus threonine-sensitive...; cd04261"
                     /db_xref="CDD:58627"
     Site            order(7,9..11,175..176,179..180)
                     /site_type="other"
                     /note="putative nucleotide binding site [chemical
                     binding]"
                     /db_xref="CDD:58627"
     Site            order(7,47,75)
                     /site_type="active"
                     /note="putative catalytic residues [active]"
                     /db_xref="CDD:58627"
     Site            order(41,47,155,183)
                     /site_type="other"
                     /note="putative Mg ion binding site [ion binding]"
                     /db_xref="CDD:58627"
     Site            order(41..42,47,75)
                     /site_type="other"
                     /note="putative aspartate binding site [chemical binding]"
                     /db_xref="CDD:58627"
     Region          273..344
                     /region_name="ACT_AKii-LysC-BS-like_1"
                     /note="ACT domains of the lysine-sensitive aspartokinase
                     isoenzyme AKII of Bacillus subtilis (BS) strain 168 and
                     related proteins; cd04913"
                     /db_xref="CDD:153185"
     Site            310..311
                     /site_type="other"
                     /note="putative allosteric regulatory site"
                     /db_xref="CDD:153185"
     Region          353..415
                     /region_name="ACT_AKii-LysC-BS-like_2"
                     /note="ACT domains of the lysine-sensitive, aspartokinase
                     (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168
                     and related domains; cd04936"
                     /db_xref="CDD:153208"
     Site            353
                     /site_type="other"
                     /note="putative allosteric regulatory residue"
                     /db_xref="CDD:153208"
     CDS             1..418
                     /gene="lysC"
                     /locus_tag="BQ03060"
                     /coded_by="NC_005955.1:379084..380340"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="catalyzes the formation of 4-phospho-L-aspartate
                     from L-aspartate and ATP, in Bacillus, lysine sensitive;
                     regulated by response to starvation."
                     /transl_table=11
                     /db_xref="GeneID:2867224"
ORIGIN      
        1 marivmkfgg tsvanierih nvarhikrev dagnevavvv samagktnel vqwtrdaspm
       61 hkdadeydvv vasgeqitag llalklqamg vnarswlgwq ipihtdnvhg saritdings
      121 fliqrfqegq vaviagfqgl apdnristlg rggsdtsava iaaavqadrc diytdvdgvy
      181 ttdpriepka rllpkvafee mlemaslgak vlqvrsvela mvhkvrtfvr ssfedpdalg
      241 mddpinssgt licdedeile qqnvtgiafa kdeaqislrr ladrpgisaa ifgplaeeri
      301 nvdmivqnis edgsktdmtf tvpsvdveka vtlleknrke igfdvlqfer nlakvsvigi
      361 gmrshagvaa tafkalsekg iniqaittse ikisilidha ytelavrtlh alygldkg
//