LOCUS       YP_188037                253 aa            linear   BCT 21-DEC-2012
DEFINITION  triosephosphate isomerase [Staphylococcus epidermidis RP62A].
ACCESSION   YP_188037
VERSION     YP_188037.1  GI:57866429
DBLINK      Project: 57663
            BioProject: PRJNA57663
DBSOURCE    REFSEQ: accession NC_002976.3
KEYWORDS    .
SOURCE      Staphylococcus epidermidis RP62A
  ORGANISM  Staphylococcus epidermidis RP62A
            Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcus.
REFERENCE   1  (residues 1 to 253)
  AUTHORS   Gill,S.R., Fouts,D.E., Archer,G.L., Mongodin,E.F., Deboy,R.T.,
            Ravel,J., Paulsen,I.T., Kolonay,J.F., Brinkac,L., Beanan,M.,
            Dodson,R.J., Daugherty,S.C., Madupu,R., Angiuoli,S.V., Durkin,A.S.,
            Haft,D.H., Vamathevan,J., Khouri,H., Utterback,T., Lee,C.,
            Dimitrov,G., Jiang,L., Qin,H., Weidman,J., Tran,K., Kang,K.,
            Hance,I.R., Nelson,K.E. and Fraser,C.M.
  TITLE     Insights on evolution of virulence and resistance from the complete
            genome analysis of an early methicillin-resistant Staphylococcus
            aureus strain and a biofilm-producing methicillin-resistant
            Staphylococcus epidermidis strain
  JOURNAL   J. Bacteriol. 187 (7), 2426-2438 (2005)
   PUBMED   15774886
REFERENCE   2  (residues 1 to 253)
  AUTHORS   Gill,S.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2004) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
REFERENCE   3  (residues 1 to 253)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-APR-2002) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AAW53875.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Staphylococcus epidermidis RP62A"
                     /strain="RP62A"
                     /db_xref="taxon:176279"
     Protein         1..253
                     /product="triosephosphate isomerase"
                     /EC_number="5.3.1.1"
                     /calculated_mol_wt=27237
     Region          4..250
                     /region_name="TIM"
                     /note="Triosephosphate isomerase (TIM) is a glycolytic
                     enzyme that catalyzes the interconversion of
                     dihydroxyacetone phosphate and
                     D-glyceraldehyde-3-phosphate. The reaction is very
                     efficient and requires neither cofactors nor metal ions.
                     TIM, usually...; cd00311"
                     /db_xref="CDD:238190"
     Region          5..252
                     /region_name="PRK14565"
                     /note="triosephosphate isomerase; Provisional"
                     /db_xref="CDD:237758"
     Site            order(9,11,97,169,175,215,234,236..237)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:238190"
     Site            order(9,12,43..45,47,50,66,84,87..88,99..100)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238190"
     Site            order(11,97,169)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238190"
     CDS             1..253
                     /gene="tpiA"
                     /locus_tag="SERP0444"
                     /coded_by="NC_002976.3:448998..449759"
                     /note="Reversibly isomerizes the ketone sugar
                     dihydroxyacetone phosphate to the aldehyde sugar
                     glyceraldehyde-3-phosphate"
                     /transl_table=11
                     /db_xref="GeneID:3242274"
ORIGIN      
        1 mrtpiiagnw kmnktvqeak dfvnelptlp dpkevesvic aptiqldalv tavkdgkakg
       61 lkigaqnayf eesgaytget spvalselgv kyvvighser rdyfhetdee vnkkahaifn
      121 hgmtpiicvg esdeereagk ankivgnqvk kaveglsddq lkevviayep iwaigtgkss
      181 tsedanemca hvrqtladls sqevadatri qyggsvkpnn ikeymaqsdi dgalvggasl
      241 kvedfvqlle gak
//