LOCUS YP_426761 384 aa linear BCT 22-DEC-2012
DEFINITION 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
[Rhodospirillum rubrum ATCC 11170].
ACCESSION YP_426761
VERSION YP_426761.1 GI:83593009
DBLINK Project: 57655
BioProject: PRJNA57655
DBSOURCE REFSEQ: accession NC_007643.1
KEYWORDS .
SOURCE Rhodospirillum rubrum ATCC 11170
ORGANISM Rhodospirillum rubrum ATCC 11170
Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
Rhodospirillaceae; Rhodospirillum.
REFERENCE 1 (residues 1 to 384)
AUTHORS Munk,A.C., Copeland,A., Lucas,S., Lapidus,A., Del Rio,T.G.,
Barry,K., Detter,J.C., Hammon,N., Israni,S., Pitluck,S.,
Brettin,T., Bruce,D., Han,C., Tapia,R., Gilna,P., Schmutz,J.,
Larimer,F., Land,M., Kyrpides,N.C., Mavromatis,K., Richardson,P.,
Rohde,M., Goker,M., Klenk,H.P., Zhang,Y., Roberts,G.P., Reslewic,S.
and Schwartz,D.C.
TITLE Complete genome sequence of Rhodospirillum rubrum type strain (S1)
JOURNAL Stand Genomic Sci 4 (3), 293-302 (2011)
PUBMED 21886856
REFERENCE 2 (residues 1 to 384)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2005) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (residues 1 to 384)
AUTHORS Copeland,A., Lucas,S., Lapidus,A., Barry,K., Detter,J.C.,
Glavina,T., Hammon,N., Israni,S., Pitluck,S., Munk,A.C.,
Brettin,T., Bruce,D., Han,C., Tapia,R., Gilna,P., Schmutz,J.,
Larimer,F., Land,M., Kyrpides,N., Mavrommatis,K. and Richardson,P.
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2005) US DOE Joint Genome Institute, 2800
Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from ABC22474.
URL -- http://www.jgi.doe.gov
Source DNA available from Gary Roberts (groberts@bact.wisc.edu)
Bacteria available from ATCC: ATCC 11170
Contacts: Gary Roberts (groberts@bact.wisc.edu)
Paul Richardson (microbes@cuba.jgi-psf.org)
Quality assurance done by JGI-Stanford
Annotation done by JGI-ORNL and JGI-PGF
Finishing done by JGI-LANL
Finished microbial genomes have been curated to close all gaps with
greater than 98% coverage of at least two independent clones. Each
base pair has a minimum q (quality) value of 30 and the total error
rate is less than one per 50000.
The JGI and collaborators endorse the principles for the
distribution and use of large scale sequencing data adopted by the
larger genome sequencing community and urge users of this data to
follow them. It is our intention to publish the work of this
project in a timely fashion and we welcome collaborative
interaction on the project and analysis.
(http://www.genome.gov/page.cfm?pageID=10506376).
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..384
/organism="Rhodospirillum rubrum ATCC 11170"
/strain="ATCC 11170"
/db_xref="ATCC:11170"
/db_xref="taxon:269796"
Protein 1..384
/product="2-C-methyl-D-erythritol 4-phosphate
cytidylyltransferase"
/EC_number="2.7.7.60"
/EC_number="4.6.1.12"
/calculated_mol_wt=40156
Region 1..383
/region_name="ispDF"
/note="bifunctional 2-C-methyl-D-erythritol 4-phosphate
cytidylyltransferase/2-C-methyl-D-erythritol
2,4-cyclodiphosphate synthase protein; Provisional;
PRK09382"
/db_xref="CDD:181813"
Region 4..217
/region_name="CDP-ME_synthetase"
/note="CDP-ME synthetase is involved in
mevalonate-independent isoprenoid production; cd02516"
/db_xref="CDD:133009"
Site order(9,11..16,23,79..82,85,105..107,207)
/site_type="other"
/note="substrate binding site"
/db_xref="CDD:133009"
Site order(108,127,135,137,154..159,183..184,186..187,190,
195..198,202..203)
/site_type="other"
/note="dimer interface"
/db_xref="CDD:133009"
Region 228..380
/region_name="MECDP_synthase"
/note="MECDP_synthase
(2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase),
encoded by the ispF gene, catalyzes the formation of
2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the
non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid
biosynthesis; cd00554"
/db_xref="CDD:100025"
Site order(228..229,231,233,235..237,241,276,278..279,281..282,
319,321,323,330,332,354,356..357,360..362,375,377,379)
/site_type="other"
/note="homotrimer interaction site [polypeptide binding]"
/db_xref="CDD:100025"
Site order(234,236,268)
/site_type="other"
/note="zinc binding site [ion binding]"
/db_xref="CDD:100025"
Site order(282,284,326..327,329..332,357..359)
/site_type="other"
/note="CDP-binding sites"
/db_xref="CDD:100025"
CDS 1..384
/locus_tag="Rru_A1674"
/coded_by="complement(NC_007643.1:1963245..1964399)"
/inference="non-experimental evidence, no additional
details recorded"
/transl_table=11
/db_xref="InterPro:IPR001228"
/db_xref="InterPro:IPR003526"
/db_xref="GeneID:3835094"
ORIGIN
1 makvaaliva agrgkrfggd lpkqyqtlgg rpilrhtlar faahpdvalv raiihpedrd
61 lygaaahgla tlldavegga erqdsvrlgl esltdvapdy vlihdgarpl vdgalidrvi
121 aaladhpgai palavadtlk rgaggmigqt vdraglwraq tpqgfrydai laahraqagt
181 mltddaavle aaggavalvd gaednakitt fadleraerl frgegeqrig sgfdvhrlgp
241 gdfvtlngir iphshglvgh sdadapmhal tdallgclna gdigrhfpps dmrwkgadsa
301 iflrhaaali talggrilnv ditilceqpk igphrarmsa rlaeileisa trvavkattt
361 eelgftgrge giaaqatali tlpf
//
