KEGG   REACTION: R01928
Entry
R01928                      Reaction                               
Name
UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase
Definition
UDP-alpha-D-galactose + Sphingosine <=> UDP + Psychosine
Equation
Reaction class
RC00005  C00015_C00052
RC00059  C00319_C01747
Enzyme
2.4.1.23        2.4.1.47
Pathway
rn00600  Sphingolipid metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.23
     R01928  UDP-alpha-D-galactose + Sphingosine <=> UDP + Psychosine
    2.4.1.47
     R01928  UDP-alpha-D-galactose + Sphingosine <=> UDP + Psychosine
Glycosyltransferase reactions [BR:br08203]
 Galactosyltransferase reactions
  R01928  Gal b1- sphingosine
Orthology
K04628  ceramide galactosyltransferase [EC:2.4.1.47]
Reference
1  [PMID:27638608]
  Authors
Sands SA, LeVine SM.
  Title
Substrate reduction therapy for Krabbe's disease.
  Journal
J Neurosci Res 94:1261-72 (2016)
DOI:10.1002/jnr.23791
Reference
2  [PMID:2512514]
  Authors
Mitsuo K, Kobayashi T, Shinnoh N, Goto I.
  Title
Biosynthesis of galactosylsphingosine (psychosine) in the twitcher mouse.
  Journal
Neurochem Res 14:899-903 (1989)
Reference
3  [PMID:13810623]
  Authors
CLELAND WW, KENNEDY EP.
  Title
The enzymatic synthesis of psychosine.
  Journal
J Biol Chem 235:45-51 (1960)
Other DBs
RHEA: 19488

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