KEGG   REACTION: R00352Help
Entry
R00352                      Reaction                               

Name
acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]
Definition
ATP + Citrate + CoA <=> ADP + Orthophosphate + Acetyl-CoA + Oxaloacetate
Equation
Comment
multi-step reaction (see R01322+R00354)
RPair
C00002_C00008 ligase
C00010_C00024 main
C00002_C00009 ligase
C00036_C00158 main
C00024_C00158 trans
Enzyme
Pathway
Citrate cycle (TCA cycle)
Carbon fixation pathways in prokaryotes
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Carbon metabolism
Orthology
K01648  
ATP citrate (pro-S)-lyase [EC:2.3.3.8]
K15230  
ATP-citrate lyase alpha-subunit [EC:2.3.3.8]
K15231  
ATP-citrate lyase beta-subunit [EC:2.3.3.8]

KEGG   REACTION: R01322Help
Entry
R01322                      Reaction                               

Name
Citrate:CoA ligase (ADP-forming)
Definition
ATP + Citrate + CoA <=> ADP + Orthophosphate + (3S)-Citryl-CoA
Equation
Comment
a part of multi-step reaction (see R00352, R01322+R00354)
RPair
C00002_C00008 ligase
C00002_C00009 ligase
C00158_C00566 main
C00010_C00566 main
Enzyme
Pathway
Carbon fixation pathways in prokaryotes
Metabolic pathways
Microbial metabolism in diverse environments
Carbon metabolism
Orthology
K15232  
citryl-CoA synthetase large subunit [EC:6.2.1.18]
K15233  
citryl-CoA synthetase small subunit

KEGG   REACTION: R00354Help
Entry
R00354                      Reaction                               

Name
(3S)-citryl-CoA oxaloacetate-lyase (acetyl-CoA-forming)
Definition
(3S)-Citryl-CoA <=> Acetyl-CoA + Oxaloacetate
Equation
Comment
a part of multi-step reaction (see R00352, R01322+R00354)
RPair
C00024_C00566 main
C00036_C00566 main
Enzyme
Pathway
Carbon fixation pathways in prokaryotes
Metabolic pathways
Microbial metabolism in diverse environments
Carbon metabolism
Orthology
K15234  
citryl-CoA lyase [EC:4.1.3.34]

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