KEGG   REACTION: R00425Help
Entry
R00425                      Reaction                               

Name
GTP 7,8-8,9-dihydrolase (diphosphate-forming)
Definition
GTP + 3 H2O <=> Formate + 2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + Diphosphate
Equation
Comment
multi-step reaction
Reaction class
RC00293  C00044_C01304
RC02504  C00044_C00058
Enzyme
Pathway
rn00740  Riboflavin metabolism
rn00790  Folate biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00125  Riboflavin biosynthesis, GTP => riboflavin/FMN/FAD
M00840  Tetrahydrofolate biosynthesis, mediated by ribA and trpF, GTP => THF
Orthology
K01497  GTP cyclohydrolase II [EC:3.5.4.25]
K14652  3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
Other DBs
RHEA: 23707

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