KEGG   REACTION: R00428Help
Entry
R00428                      Reaction                               

Name
GTP 8,9-hydrolase
Definition
GTP + H2O <=> Formamidopyrimidine nucleoside triphosphate
Equation
Comment
the first step of four-step reaction (see R00424, R00428+R05046+R05048+R04639)
subsequently R05046
RPair
C00044_C05922 main [RC:RC00294]
Enzyme
Pathway
Folate biosynthesis
Metabolic pathways
Module
M00126  
Tetrahydrofolate biosynthesis, GTP => THF
Orthology
K01495  
GTP cyclohydrolase I [EC:3.5.4.16]
K09007  
GTP cyclohydrolase I [EC:3.5.4.16]

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