KEGG   REACTION: R00940Help
Entry
R00940                      Reaction                               

Name
5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase
Definition
Tetrahydrofolate + 2 NADP+ <=> Folate + 2 NADPH + 2 H+
Equation
C00101 + 2 C00006 <=> C00504 + 2 C00005 + 2 C00080
Comment
two-step reaction (see R00939+R02236)
NAD+ (see R00937)
RPair
C00005_C00006 cofac [RC:RC00001]
C00101_C00504 main [RC:RC00110]
Enzyme
Pathway
One carbon pool by folate
Folate biosynthesis
Metabolic pathways
Orthology
K00287  
dihydrofolate reductase [EC:1.5.1.3]
K13998  
dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]

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