KEGG   REACTION: R01078Help
Entry
R01078                      Reaction                               

Name
dethiobiotin:sulfur sulfurtransferase
Definition
Dethiobiotin + Sulfur donor + 2 S-Adenosyl-L-methionine + 2 e- + 2 H+ <=> Biotin + 2 L-Methionine + 2 5'-Deoxyadenosine
Equation
C01909 + C17023 + 2 C00019 + 2 C05359 + 2 C00080 <=> C00120 + 2 C00073 + 2 C05198
Comment
the reactant sulfur is not elemental sulfur, but it may be from the enzyme itself ([2Fe-2S] iron-sulfur centre)
multi-step reaction
RPair
C00120_C01909 main [RC:RC00441]
C00019_C00073 cofac [RC:RC00021]
C00019_C05198 cofac
Enzyme
Pathway
Biotin metabolism
Metabolic pathways
Module
M00123  
Biotin biosynthesis, pimeloyl-ACP/CoA => biotin
M00573  
Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin
M00577  
Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin
Orthology
K01012  
biotin synthase [EC:2.8.1.6]

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