KEGG   REACTION: R01218
Entry
R01218                      Reaction                               
Name
5,10-methylenetetrahydrofolate:NAD+ oxidoreductase
Definition
5,10-Methylenetetrahydrofolate + NAD+ <=> 5,10-Methenyltetrahydrofolate + NADH
Equation
Reaction class
RC00001  C00003_C00004
RC00202  C00143_C00445
Enzyme
Pathway
rn00670  One carbon pool by folate
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00141  C1-unit interconversion, eukaryotes
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.15
     R01218  5,10-Methylenetetrahydrofolate + NAD+ <=> 5,10-Methenyltetrahydrofolate + NADH
Orthology
K00295  methylenetetrahydrofolate dehydrogenase (NAD+) [EC:1.5.1.15]
K13403  methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
Other DBs
RHEA: 22895

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