KEGG   REACTION: R01221Help
Entry
R01221                      Reaction                               

Name
glycine synthase;
glycine cleavage system
Definition
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
Equation
Comment
multienzyme system
multi-step reaction (see R03425+R04125+R03815)
RPair
C00003_C00004 cofac [RC:RC00001]
C00101_C00143 main [RC:RC00022]
C00014_C00037 main [RC:RC02834]
C00011_C00037 leave
Enzyme
1.4.4.2         1.8.1.4         2.1.2.10
Pathway
Glyoxylate and dicarboxylate metabolism
Biosynthesis of secondary metabolites
Carbon metabolism
Orthology
K00281  
glycine dehydrogenase [EC:1.4.4.2]
K00282  
glycine dehydrogenase subunit 1 [EC:1.4.4.2]
K00283  
glycine dehydrogenase subunit 2 [EC:1.4.4.2]
K00382  
dihydrolipoamide dehydrogenase [EC:1.8.1.4]
K00605  
aminomethyltransferase [EC:2.1.2.10]
K02437  
glycine cleavage system H protein

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