KEGG   REACTION: R01814Help
Entry
R01814                      Reaction                               

Name
L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)
Definition
Tetrahydrobiopterin + L-Tryptophan + Oxygen <=> 5-Hydroxy-L-tryptophan + Dihydrobiopterin + H2O
Equation
Comment
two-step reaction (see R07213+R04734)
RPair
C00001_C00007 cofac
C00268_C00272 cofac [RC:RC00023]
C00078_C00643 main [RC:RC00490]
C00007_C00643 leave
Enzyme
Pathway
Tryptophan metabolism
Metabolic pathways
Module
M00037  
Melatonin biosynthesis, tryptophan => serotonin => melatonin
Orthology
K00502  
tryptophan 5-monooxygenase [EC:1.14.16.4]

DBGET integrated database retrieval system