KEGG   REACTION: R01837Help
Entry
R01837                      Reaction                               

Name
3beta-Hydroxyandrost-5-en-17-one:NAD+ 3-oxidoreductase/delta5-delta-4 isomerase
Definition
Dehydroepiandrosterone + NAD+ <=> Androstenedione + NADH + H+
Equation
Comment
NADP+ (see R01839)
Reactant pair
C00003_C00004 cofac [RC:RC00001]
C00280_C01227 main [RC:RC00146]
Enzyme
1.1.1.145       5.3.3.1
Pathway
Steroid hormone biosynthesis
Metabolic pathways
Module
M00110  
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Orthology
K00070  
3beta-hydroxy-delta5-steroid dehydrogenase / steroid delta-isomerase [EC:1.1.1.145 5.3.3.1]
K01822  
steroid delta-isomerase [EC:5.3.3.1]

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