KEGG   REACTION: R02351Help
Entry
R02351                      Reaction                               

Name
19-oxoandrostenedione,NADPH---hemoprotein reductase:oxygen oxidoreductase (aromatizing, formate-forming)
Definition
19-Oxoandrost-4-ene-3,17-dione + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Estrone + Formate + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
aromatase, ARO
following after R04759
Reaction class
C00468_C05297
Enzyme
Pathway
Steroid hormone biosynthesis
Metabolic pathways
Module
M00110  
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Orthology
K07434  
aromatase [EC:1.14.14.14]

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