KEGG   REACTION: R02351Help
Entry
R02351                      Reaction                               

Name
19-oxoandrostenedione,reduced-flavoprotein:oxygen oxidoreductase (aromatizing, formate-forming)
Definition
Estrone + Formate + Oxidized flavoprotein + H2O <=> 19-Oxoandrost-4-ene-3,17-dione + Oxygen + Reduced flavoprotein
Equation
Comment
aromatase, ARO
P-450 reductase (ec 1.6.2.4) is the flavoprotein and re-reduced by NADPH (see R08551)
following after R04759
RPair
C00001_C00007 cofac
C00468_C05297 main [RC:RC02649]
C00007_C00058 leave
C00058_C05297 main [RC:RC01535]
Enzyme
Pathway
Steroid hormone biosynthesis
Metabolic pathways
Module
M00110  
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Orthology
K07434  
aromatase [EC:1.14.14.14]

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