KEGG   REACTION: R03408Help
Entry
R03408                      Reaction                               

Definition
Dehydroepiandrosterone + H+ + Oxygen + NADPH <=> 16alpha-Hydroxydehydroepiandrosterone + NADP+ + H2O
Equation
Comment
steroid 16alpha-hydroxylase
RPair
C00005_C00006 cofac [RC:RC00001]
C00001_C00007 cofac
C01227_C05139 main [RC:RC00704]
C00007_C05139 leave
Enzyme
1.14.13.-       1.14.14.1
Pathway
Steroid hormone biosynthesis
Orthology
K07408  
cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1]
K07409  
cytochrome P450, family 1, subfamily A, polypeptide 2 [EC:1.14.14.1]
K07412  
cytochrome P450, family 2, subfamily B [EC:1.14.14.1]
K07413  
cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
K07414  
cytochrome P450, family 2, subfamily D [EC:1.14.14.1]
K07415  
cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-]
K07424  
cytochrome P450, family 3, subfamily A [EC:1.14.14.1]
K17689  
cytochrome P450, family 3, subfamily A, polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-]
K17690  
cytochrome P450, family 3, subfamily A, polypeptide 5 [EC:1.14.14.1]
K17691  
cytochrome P450, family 3, subfamily A, polypeptide 7 [EC:1.14.14.1]

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