KEGG   REACTION: R03953Help
Entry
R03953                      Reaction                               

Definition
3-Iodo-L-tyrosine + 3,5-Diiodo-L-tyrosine + Hydrogen peroxide <=> Triiodothyronine + Dehydroalanine + 2 H2O
Equation
Comment
thyroid peroxidase, TPO
reaction on thyroglobulin [KO:K10809] (see R08522)
RPair
C00001_C00027 cofac
C01060_C02465 main [RC:RC00878]
C02218_C02515 main [RC:RC01037]
C02465_C02515 trans
Enzyme
Pathway
Tyrosine metabolism
Metabolic pathways
Module
M00043  
Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Orthology
K00431  
thyroid peroxidase [EC:1.11.1.8]

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