KEGG   REACTION: R04037
Entry
R04037                      Reaction                               
Name
1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase
Definition
Phosphoribosyl-AMP + H2O <=> 5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide
Equation
C02741 + C00001 <=> C04896
Reaction class
RC01055  C02741_C04896
Enzyme
3.5.4.19
Pathway
rn00340  Histidine metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01230  Biosynthesis of amino acids
Module
M00026  Histidine biosynthesis, PRPP => histidine
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.19
     R04037  Phosphoribosyl-AMP + H2O <=> 5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide
Orthology
K01496  phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
K11755  phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]
K14152  phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
Other DBs
RHEA: 20052

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (7672)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (7669)   
All databases (7687)   

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