KEGG   REACTION: R04440Help
Entry
R04440                      Reaction                               

Name
(R)-2,3-Dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)
Definition
(R)-2,3-Dihydroxy-3-methylbutanoate + NADP+ <=> 3-Hydroxy-3-methyl-2-oxobutanoic acid + NADPH + H+
Equation
Reaction class
RC00001  C00005_C00006
RC00726  C04181_C04272
Enzyme
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01130  Biosynthesis of antibiotics
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
Orthology
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Other DBs
RHEA: 31142

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