KEGG   REACTION: R04440Help
Entry
R04440                      Reaction                               

Name
(R)-2,3-Dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)
Definition
(R)-2,3-Dihydroxy-3-methylbutanoate + NADP+ <=> 3-Hydroxy-3-methyl-2-oxobutanoic acid + NADPH + H+
Equation
RPair
C00005_C00006 cofac [RC:RC00001]
C04181_C04272 main [RC:RC00726]
Enzyme
Pathway
Valine, leucine and isoleucine biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids
Module
M00019  
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
Orthology
K00053  
ketol-acid reductoisomerase [EC:1.1.1.86]

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