KEGG   REACTION: R04444Help
Entry
R04444                      Reaction                               

Name
L-1-pyrroline-3-hydroxy-5-carboxylate:NAD+ oxidoreductase
Definition
L-1-Pyrroline-3-hydroxy-5-carboxylate + NAD+ + 2 H2O <=> L-erythro-4-Hydroxyglutamate + NADH + H+
Equation
Comment
possibly two-step reaction (R04443+R05051)
NADPH (see R04445)
Reactant pair
C00003_C00004 cofac [RC:RC00001]
C04281_C05947 main [RC:RC00255]
Enzyme
Pathway
Arginine and proline metabolism
Metabolic pathways
Orthology
K00294  
1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
K13821  
RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]

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