KEGG   REACTION: R05046Help
Entry
R05046                      Reaction                               

Name
formamidopyrimidine nucleoside triphosphate amidohydrolase
Definition
Formamidopyrimidine nucleoside triphosphate + H2O <=> 2,5-Diaminopyrimidine nucleoside triphosphate + Formate
Equation
Comment
the second step of four-step reaction (see R00424, R00428+R05046+R05048+R04639)
following after R00428
subsequently R05048
Reaction class
C05922_C05923
C00058_C05922
Enzyme
Pathway
Folate biosynthesis
Metabolic pathways
Module
M00126  
Tetrahydrofolate biosynthesis, GTP => THF
M00841  
Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF
M00842  
Tetrahydrobiopterin biosynthesis, GTP => BH4
M00843  
L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4
Orthology
K01495  
GTP cyclohydrolase IA [EC:3.5.4.16]
K09007  
GTP cyclohydrolase IB [EC:3.5.4.16]

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