KEGG   REACTION: R06473
Entry
R06473                      Reaction                               
Definition
5-Oxoavermectin ''1a'' aglycone + NADPH + H+ <=> Avermectin B1a aglycone + NADP+
Equation
C11978 + C00005 + C00080 <=> C11979 + C00006
Comment
C-5 ketoreductase,AveF
Reaction class
RC00001  C00005_C00006
RC01528  C11978_C11979
Pathway
rn00522  Biosynthesis of 12-, 14- and 16-membered macrolides
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00777  Avermectin biosynthesis, 2-methylbutanoyl-CoA/isobutyryl-CoA => 6,8a-Seco-6,8a-deoxy-5-oxoavermectin 1a/1b aglycone => avermectin A1a/B1a/A1b/B1b
Orthology
K14373  C-5 ketoreductase

  All links  
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG RCLASS (2)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
All databases (16)   

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