KEGG   REACTION: R07085Help
Entry
R07085                      Reaction                               

Name
benzo[a]pyrene-7,8-diol, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Definition
Benzo[a]pyrene-7,8-diol + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide + NADP+ + H2O
Equation
Comment
CYP1A1, CYP1B1, CYP2C9, CYP3A4
Reaction class
RC00001  C00005_C00006
RC01727  C14852_C14853
Enzyme
1.14.13.-       1.14.14.1       1.14.14.-
Pathway
rn00980  Metabolism of xenobiotics by cytochrome P450
Orthology
K07408  cytochrome P450 family 1 subfamily A polypeptide 1 [EC:1.14.14.1]
K07410  cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]
K17689  cytochrome P450 family 3 subfamily A polypeptide 4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.13.-]
K17719  cytochrome P450 family 2 subfamily C polypeptide 9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]

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