KEGG   REACTION: R07251Help
Entry
R07251                      Reaction                               

Name
acyl-CoA:malonyl-CoA C-acyltransferase (dihydromonacolin L-[acp]-forming)
Definition
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein <=> Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O
Equation
9 C00083 + 11 C00005 + 10 C00080 + C00019 + C00229 <=> C21108 + 9 C00010 + 9 C00011 + 11 C00006 + C00021 + 6 C00001
Comment
multi-step reaction
Acy-carrier protein is acp domain of LOVB [KO:K20981].
Reaction class
C00019_C00021
C00010_C00083
C00229_C21108
Enzyme
Orthology
K20981  
lovastatin nonaketide synthase [EC:2.3.1.161]
K20982  
lovastatin enoyl reductase [EC:2.3.1.161]

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