KEGG REACTION: R07251

REACTION: R07251

Entry

R07251 Reaction

Name

acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing)

Definition

Acetyl-CoA + 8 Malonyl-CoA + 11 NADPH + 11 H+ + S-Adenosyl-L-methionine <=> Dihydromonacolin L + 9 CoA + 8 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O

Equation

C00024 + 8 C00083 + 11 C00005 + 11 C00080 + C00019 <=> C15536 + 9 C00010 + 8 C00011 + 11 C00006 + C00021 + 6 C00001

Comment

multi-step reaction

RPair

RP00001	C00005_C00006 cofac
RP00004	C00019_C00021 main
RP00007	C00010_C00024 main
RP00051	C00010_C00083 main
RP05694	C00011_C00083 leave
RP08518	C00001_C00083 leave
RP10708	C00019_C15536 trans
RP10739	C00024_C15536 trans
RP10897	C00083_C15536 trans
RP13914	C00083_C15536 trans
RP13915	C00083_C15536 trans
RP13916	C00083_C15536 trans
RP13917	C00083_C15536 trans
RP13918	C00083_C15536 trans
RP13919	C00083_C15536 trans
RP13920	C00083_C15536 trans
RP13921	C00001_C00024 leave

Enzyme

2.3.1.161

All links

Ontology (1)   
   KEGG BRITE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (20)   
   KEGG ENZYME (1)   
   KEGG RPAIR (17)   
   KEGG RCLASS (2)   
All databases (32)   

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