KEGG   REACTION: R07599Help
Entry
R07599                      Reaction                               

Definition
3-Methyl-2-oxobutanoic acid + Thiamin diphosphate <=> 2-Methyl-1-hydroxypropyl-ThPP + CO2
Equation
Comment
Oxo-acid dehydrogenase complexes (see R01701), subsequently R07600
RPair
C00011_C00141 leave
C00068_C15976 main [RC:RC00027]
C00141_C15976 main [RC:RC02949]
Enzyme
Pathway
Valine, leucine and isoleucine degradation
Metabolic pathways
Orthology
K00166  
2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:1.2.4.4]
K00167  
2-oxoisovalerate dehydrogenase E1 component beta subunit [EC:1.2.4.4]
K11381  
2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]

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