KEGG   REACTION: R07602Help
Entry
R07602                      Reaction                               

Definition
3-Methyl-1-hydroxybutyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine + Thiamin diphosphate
Equation
Comment
Oxo-acid dehydrogenase complexes (see R01702), following after R07601
RPair
C00068_C15974 main [RC:RC00027]
C15972_C15975 main [RC:RC00627]
C15974_C15975 main [RC:RC02883]
Enzyme
Pathway
Valine, leucine and isoleucine degradation
Metabolic pathways
Module
M00036  
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Orthology
K00166  
2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:1.2.4.4]
K00167  
2-oxoisovalerate dehydrogenase E1 component beta subunit [EC:1.2.4.4]
K11381  
2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]

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