KEGG   REACTION: R08255Help
Entry
R08255                      Reaction                               

Definition
Irinotecan + H2O <=> SN-38 + 1,4'-Bipiperidine-1'-carboxylic acid
Equation
Comment
carboxylesterase
RPair
C11173_C16641 main [RC:RC00476]
C16641_C16836 main [RC:RC00475]
C00001_C16836 leave
Enzyme
Pathway
Drug metabolism - other enzymes
Orthology
K01044  
carboxylesterase 1 [EC:3.1.1.1]
K03927  
carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56]

DBGET integrated database retrieval system