KEGG   REACTION: R08257Help
Entry
R08257                      Reaction                               
Definition
Irinotecan + 2 Reduced flavoprotein + 2 Oxygen <=> NPC + Glutaral + 2 Oxidized flavoprotein + 2 H2O
Equation
C16641 + 2 C03024 + 2 C00007 <=> C16543 + C12518 + 2 C03161 + 2 C00001
Comment
CYP3A4
RPair
C00001_C00007 cofac
C16543_C16641 main
C12518_C16641 main
C00007_C12518 leave
Enzyme
Pathway
Drug metabolism - other enzymes
Orthology
K07424  
cytochrome P450, family 3, subfamily A [EC:1.14.14.1]
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