KEGG   REACTION: R08275Help
Entry
R08275                      Reaction                               

Definition
Cyclophosphamide + NADPH + H+ + Oxygen <=> 4-Hydroxycyclophosphamide + NADP+ + H2O
Equation
Comment
CYP2B6, CYP2C19, CYP3A4, CYP2C9
RPair
C00005_C00006 cofac
C00001_C00007 cofac
C00007_C07643 leave
C07643_C07888 main
Enzyme
1.14.13.-
Pathway
Drug metabolism - cytochrome P450
Orthology
K17689  
cytochrome P450, family 3, subfamily A, polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-]
K17709  
cytochrome P450, family 2, subfamily B, polypeptide 6 [EC:1.14.13.-]
K17719  
cytochrome P450, family 2, subfamily C, polypeptide 9 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]
K17721  
cytochrome P450, family 2, subfamily C, polypeptide 19 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]

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