KEGG REACTION: R08294

REACTION: R08294

Entry

R08294 Reaction

Definition

Lidocaine + NADPH + Oxygen + H+ <=> 3-Hydroxylidocaine + NADP+ + H2O

Equation

C07073 + C00005 + C00007 + C00080 <=> C16560 + C00006 + C00001

Comment

CYP1A2, CYP3A4

RPair

RP00001	C00005_C00006 cofac
RP00013	C00001_C00007 leave
RP12847	C00007_C16560 leave
RP13113	C07073_C16560 main

Enzyme

1.14.14.1

Pathway

rn00982

Drug metabolism - cytochrome P450

Orthology

K07409	cytochrome P450, family 1, subfamily A, polypeptide 2 [EC:1.14.14.1]
K07424	cytochrome P450, family 3, subfamily A [EC:1.14.14.1]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG RPAIR (4)   
   KEGG RCLASS (1)   
Gene (115)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (113)   
All databases (131)   

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