KEGG   REACTION: R08312Help
Entry
R08312                      Reaction                               

Definition
Carbamazepine + NADPH + H+ + Oxygen <=> Carbamazepine-10,11-epoxide + NADP+ + H2O
Equation
Comment
CYP3A4, CYP2C8
RPair
C00005_C00006 cofac [RC:RC00001]
C00001_C00007 cofac
C00007_C07496 leave
C06868_C07496 main [RC:RC02228]
Enzyme
1.14.13.-       1.14.14.1
Pathway
Drug metabolism - cytochrome P450
Orthology
K17689  
cytochrome P450, family 3, subfamily A, polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-]
K17718  
cytochrome P450, family 2, subfamily C, polypeptide 8 [EC:1.14.14.1]

DBGET integrated database retrieval system