KEGG REACTION: R08313

REACTION: R08313

Entry

R08313 Reaction

Definition

Carbamazepine + NADPH + H+ + Oxygen <=> 3-Hydroxycarbamazepine + NADP+ + H2O

Equation

C06868 + C00005 + C00080 + C00007 <=> C16602 + C00006 + C00001

Comment

CYP3A4, CYP2B6

RPair

RP00001	C00005_C00006 cofac
RP00013	C00001_C00007 cofac
RP12850	C00007_C16602 leave
RP13102	C06868_C16602 main

Enzyme

1.14.14.1

Pathway

rn00982

Drug metabolism - cytochrome P450

Orthology

K07412	cytochrome P450, family 2, subfamily B [EC:1.14.14.1]
K07424	cytochrome P450, family 3, subfamily A [EC:1.14.14.1]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG RPAIR (4)   
   KEGG RCLASS (1)   
Gene (129)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (127)   
All databases (145)   

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