KEGG REACTION: R08325

REACTION: R08325

Entry

R08325 Reaction

Definition

Valproic acid + NADPH + H+ + Oxygen <=> 4-Hydroxyvalproic acid + NADP+ + H2O

Equation

C07185 + C00005 + C00080 + C00007 <=> C16649 + C00006 + C00001

Comment

CYP2C9, CYP2A6, CTP2B6

RPair

RP00001	C00005_C00006 cofac
RP00013	C00001_C00007 cofac
RP12851	C00007_C16649 leave
RP13121	C07185_C16649 main

Enzyme

1.14.14.1

Pathway

rn00982

Drug metabolism - cytochrome P450

Orthology

K07411	cytochrome P450, family 2, subfamily A [EC:1.14.14.1]
K07412	cytochrome P450, family 2, subfamily B [EC:1.14.14.1]
K07413	cytochrome P450, family 2, subfamily C [EC:1.14.14.1]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG RPAIR (4)   
   KEGG RCLASS (1)   
Gene (137)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (134)   
All databases (153)   

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