KEGG   REACTION: R08390Help
Entry
R08390                      Reaction                               

Definition
Retinoate + NADPH + H+ + Oxygen <=> all-trans-18-Hydroxyretinoic acid + NADP+ + H2O
Equation
Comment
CYP1A1, CYP2A6, CYP2B6, CYP2C8/9/18, CYP3A4/5/7, CYP26, CYP4A11
Reaction class
RC00001  C00005_C00006
RC00724  C00777_C16679
Enzyme
1.14.13.-       1.14.14.1       1.14.14.-       1.14.15.3
Pathway
rn00830  Retinol metabolism
Orthology
K07408  cytochrome P450 family 1 subfamily A polypeptide 1 [EC:1.14.14.1]
K07411  cytochrome P450 family 2 subfamily A [EC:1.14.14.1]
K07412  cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07413  cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07424  cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07425  alkane 1-monooxygenase [EC:1.14.15.3]
K07437  cytochrome P450 family 26 subfamily A
K12664  cytochrome P450 family 26 subfamily B
K12665  cytochrome P450 family 26 subfamily C
K17683  cytochrome P450 family 2 subfamily A polypeptide 6 [EC:1.14.13.-]
K17687  alkane 1-monooxygenase [EC:1.14.15.3]
K17689  cytochrome P450 family 3 subfamily A polypeptide 4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.13.-]
K17690  cytochrome P450 family 3 subfamily A polypeptide 5 [EC:1.14.14.1]
K17691  cytochrome P450 family 3 subfamily A polypeptide 7 [EC:1.14.14.1]
K17709  cytochrome P450 family 2 subfamily B polypeptide 6 [EC:1.14.13.-]
K17718  cytochrome P450 family 2 subfamily C polypeptide 8 [EC:1.14.14.1]
K17719  cytochrome P450 family 2 subfamily C polypeptide 9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]
K17720  cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]

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