KEGG   REACTION: R08517Help
Entry
R08517                      Reaction                               

Name
17alpha-Hydroxypregnenolone,NADPH---hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating, acetate-releasing)
Definition
17alpha-Hydroxypregnenolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Dehydroepiandrosterone + Acetate + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
17alpha-hydroxylase/17,20-lyase
Reaction class
C01227_C05138
C00033_C05138
Enzyme
Pathway
Steroid hormone biosynthesis
Metabolic pathways
Module
M00110  
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Orthology
K00512  
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]

DBGET integrated database retrieval system