KEGG   REACTION: R08517Help
Entry
R08517                      Reaction                               

Name
17alpha-hydroxypregnenolone,hydrogen-donor:oxygen oxidoreductase (side-chain-cleaving, acetate-formig)
Definition
17alpha-Hydroxypregnenolone + Reduced acceptor + Oxygen <=> Dehydroepiandrosterone + Acetate + Acceptor + H2O
Equation
Comment
17alpha-hydroxylase/17,20-lyase
P-450 reductase is acceptor and re-reduced by NADPH
RPair
C00001_C00007 cofac
C00033_C05138 main
C01227_C05138 main
C00007_C00033 leave
Enzyme
Pathway
Steroid hormone biosynthesis
Metabolic pathways
Orthology
K00512  
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone aldolase [EC:1.14.99.9 4.1.2.30]

DBGET integrated database retrieval system