KEGG   REACTION: R08569Help
Entry
R08569                      Reaction                               

Name
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate:NAD+ oxidoreductase (deaminating)
Definition
2-Amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid + H2O + NAD+ <=> 3-Dehydroquinate + Ammonia + NADH + H+
Equation
Comment
two-step reaction (oxidative deamination, cyclization)
possibly intermediate (3,7-dideoxy-D-threo-hept-2,6-diulosonic acid)
RPair
C00003_C00004 cofac
C00001_C00944 leave
C00944_C16850 main
C00014_C16850 leave
Enzyme
Pathway
Phenylalanine, tyrosine and tryptophan biosynthesis
Biosynthesis of secondary metabolites
Orthology
K11646  
3-dehydroquinate synthase II [EC:1.4.1.24]
Reference
1  [PMID:15182204]
White RH.
L-Aspartate semialdehyde and a 6-deoxy-5-ketohexose 1-phosphate are the precursors to the aromatic amino acids in Methanocaldococcus jannaschii.
Biochemistry. 43 (2004) 7618-27.

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