| Entry |
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| Name |
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate:NAD+ oxidoreductase (deaminating)
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| Definition |
2-Amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid + H2O + NAD+ <=> 3-Dehydroquinate + Ammonia + NADH + H+
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| Equation |
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| Comment |
two-step reaction (oxidative deamination, cyclization)
possibly intermediate (3,7-dideoxy-D-threo-hept-2,6-diulosonic acid)
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| RPair |
| C00003_C00004 cofac | | C00001_C00944 leave | | C00944_C16850 main | | C00014_C16850 leave |
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| Enzyme |
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| Pathway |
| Phenylalanine, tyrosine and tryptophan biosynthesis | | Biosynthesis of secondary metabolites |
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| Orthology |
| 3-dehydroquinate synthase II [EC: 1.4.1.24] |
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| Reference |
1 [PMID: 15182204]
White RH.
L-Aspartate semialdehyde and a 6-deoxy-5-ketohexose 1-phosphate are the precursors to the aromatic amino acids in Methanocaldococcus jannaschii.
Biochemistry. 43 (2004) 7618-27. |
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